[BiO BB] Question about selection in evolution
Daniel Amelang
danny at amelang.net
Tue Apr 19 17:22:31 EDT 2005
>Does anyone know what kinds of genes that underwent positive selection the
>most?
>Could you also refer me some related paper about gene evolution?
>
>
The other day I was playing around with some software that determines
the level of positive/negative selection at the amino acid level for a
given gene. Perhaps it would help. It's called TreeSAAP
http://inbio.byu.edu/faculty/dam83/cdm/
Here's the paper introducing it:
http://bioinformatics.oupjournals.org/cgi/content/abstract/19/5/671
Although it may be more fine-grained that what you need, you could
theoretically use it to determine if a gene underwent positive selection
or not. TreeSAAP will tell you where in the sequence the selection
occured and for what amino acid property. Sounds like more that you need
:) Hey, it was worth mentioning.
Dan
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