[BiO BB] Post Doctoral Position in Macromolecular Crystallography

[oliviero.carugo at univie.ac.at]

*Postdoctoral Position in Macromolecular Crystallography*: *Radiation 
damage on metal centers and Soft X-rays Studies* 

*Commencing date:* As soon as possible, after closing date 

*Job description:* BIOXHIT (Biocrystallography on a Highly Integrated 
Technology Platform for European Structural Genomics) is an integrated 
project within the EU's 6th Framework Programme. It brings together 
scientists at all European synchrotrons and leading software developers 
to produce a highly effective technology platform for Structural 
Genomics. It aims to consolidate the process of bio-macromolecular 
structure solution from the bottom up. 

The successful applicant will work in a stimulating scientific 
environment at the Macromolecular crystallography group at the 
Department of Biomolecular Structural Chemistry, a member of Max F. 
Perutz Laboratories - University Departments at the Vienna Biocenter, 
University of Vienna. The Department is equipped to carry out all steps 
from gene cloning to structural analysis including recently installed 
Bruker X8 PROTEUM system. The Group has additionally access to the high 
throughput nano-drop crystallisation robotics operational at Institute 
of Molecular Pathology (IMP), based at Campus Vienna Biocenter as well 
as to major European synchrotron high brilliance X-ray sources. 

The selected candidate will focus on two related projects: one will be 
the investigation of radiation damage on the active centers of selected 
set of metallo-enzymes and the study effect of free-radical and electron 
scavengers with the aim to reduce such damage to these metal centers. 
The other will be the use of soft X-rays in macromolecular 
crystallography for phasing as well as functional characterization 
purposes, with the focus on the design of the diffraction experiment. 

*Qualifications and experience:* In addition to a PhD in a relevant 
area, experience in protein expression and purification and in 
macromolecular crystallography techniques including crystal growth, 
data-collection as well as familiarity with standard crystallographic 
software are required. 

*Contract:* A 2 year contract will be offered to the successful candidate. 

*Closing date:* 15 January 2006 

*Web pages:* 
www.bioxhit.org <http://www.bioxhit.org/>; 
http://www.mfpl.ac.at/content/index.php?cid=58 
http://www.univie.ac.at/biolchem 


Further information can be obtained from Kristina Djinovic Carugo 
kristina.djinovic at univie.ac.at <mailto:kristina.djinovic at univie.ac.at>. 

University of Vienna is an equal opportunity employer. 

*To apply for this position, please email a detailed CV with concise 
description of research experience and the names and addresses of at 
least two referees to: kristina.djinovic at univie.ac.at 
<mailto:kristina.djinovic at univie.ac.at>, ****AND**** register at the 
University of Vienna: 
http://gerda.univie.ac.at/personal/artikel.php?Sprach_ID=1&Art_ID=668