I've constructed RPMs for various Open Source tools and just updated the NCBI rpm to incorporate the new version of BLAST 2.2.15. All RPMs are available for download from http://serine.umdnj.edu/~golharam/biorpms. If you have any questions, please feel free to email me. -- Ryan Golhar, PhD - golharam at umdnj.edu The Informatics Institute of UMDNJ