[BiO BB] Reactome version 20 released
Reactome-Knowledgebase at reactome.org
Reactome-Knowledgebase at reactome.org
Thu Mar 1 14:32:54 EST 2007
Version 20 of the Reactome Knowledgebase has been released and is
accessible at http://www.reactome.org!
Reactome is a curated knowledgebase developed and maintained by the
Reactome Knowledgebase team (Lincoln Stein's group at CSHL and Ewan
Birney's group at European Bioinformatics Institute). Reactome
covers human biological processes ranging from basic pathways of
metabolism to complex events such as hormonal signaling and
apoptosis. The information in Reactome is provided by expert bench
biologists, and edited and managed as a relational database by the
Reactome staff. New material is peer-reviewed and revised as
necessary before publication to the web. Reactome entries are linked
to corresponding ones in NCBI, Entrez Gene, RefSeq, OMIM, Ensembl
genome annotations, HapMap, UCSC Genome Browser, KEGG, ChEBI and Gene
Ontology (GO).
New topics released in Version 20 are Fibroblast Growth Factor
Receptor (FGFR) signaling, Epidermal Growth Factor Receptor (EGFR)
signaling under signaling pathways, Gap junction trafficking under
cell biology, and Porphyrin metabolism, Digestion of dietary
carbohydrate and lipid under metabolic pathways. Additional events
for HIV REV protein interactions, and Influenza virus RNP assembly
have been added to corresponding infectious disease pathways.
The standard display feature allows the user to choose the focus
species annotations - curated (for human) and electronically inferred
(for 22 other species). Updated release statistics and the Editorial
Calendar are available. A SOAP based Web Services API is available
aong with other resources to access the Reactome data from Download
page. As before, Reactome data can be exported in SMBL, Protégé, and
BioPAX level 2 formats.
Like everything in Reactome, these downloaded and exported materials
can be reused and redistributed freely. For questions and comments
please reply to this message or write to help at reactome.org
-Gopal Gopinathrao
Reactome, CSHL
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