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<DIV><FONT color=#0000ff face="Comic Sans MS"><SPAN
class=120004211-14052002>Thanks Cat..that is a big help!!</SPAN></FONT></DIV>
<DIV><FONT color=#0000ff face="Comic Sans MS"><SPAN
class=120004211-14052002></SPAN></FONT> </DIV>
<DIV><FONT color=#0000ff face="Comic Sans MS"><SPAN
class=120004211-14052002>Jay</SPAN></FONT></DIV>
<BLOCKQUOTE>
<DIV align=left class=OutlookMessageHeader dir=ltr><FONT face=Tahoma
size=2>-----Original Message-----<BR><B>From:</B>
bio_bulletin_board-admin@bioinformatics.org
[mailto:bio_bulletin_board-admin@bioinformatics.org]<B>On Behalf Of
</B>Catherine Velazquez<BR><B>Sent:</B> Friday, May 10, 2002 7:05
PM<BR><B>To:</B> bio_bulletin_board@bioinformatics.org<BR><B>Subject:</B> RE:
[BiO BB] PhD post in plasmid bioinformatics, genomics and
ecology<BR><BR></DIV></FONT>
<DIV>
<DIV>
<P>Jay,</P>
<P>I know there are courses in both bioinformatics programming and use of
bioinformatic-esque databases at both San Jose State University <A
href="http://www.sjsu.edu">www.sjsu.edu</A> and Cal State Hayward. </P>
<P>The University of California, Santa Cruz has a B.S. degree in
Bioinformatics that started in Fall '00. <A
href="http://www.ucsc.edu">www.ucsc.edu</A></P>
<P>People can register as Open University students, Post-Bacc students or
enroll in the 2nd degree program. </P>
<P> </P>
<P>Toodles,</P>
<P>Cat<BR></P></DIV>
<DIV></DIV><BR><BR><BR>
<DIV></DIV>
<DIV align=center><A
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<DIV></DIV>
<DIV></DIV>
<DIV></DIV>
<DIV></DIV>
<DIV></DIV>>From: "Jay N Swamy" <JAY@CHARTERGLOBAL.COM>
<DIV></DIV>>Reply-To: bio_bulletin_board@bioinformatics.org
<DIV></DIV>>To: <BIO_BULLETIN_BOARD@BIOINFORMATICS.ORG>
<DIV></DIV>>Subject: RE: [BiO BB] PhD post in plasmid bioinformatics,
genomics and ecology
<DIV></DIV>>Date: Fri, 10 May 2002 10:10:19 -0400
<DIV></DIV>>
<DIV></DIV>>Hi Meredith, Dawn,
<DIV></DIV>>
<DIV></DIV>>I work with an IT Consulting firm with a specialized focus on
serving
<DIV></DIV>>pharmaceutical companies. A number of our employees are keen on
getting
<DIV></DIV>>trained and moving into the area of Bioinformatics. It would be
a great help
<DIV></DIV>>if you could let us know what sort of training these IT
professionals need
<DIV></DIV>>to undertake and also if you know of any Institutes, bodies or
Universities
<DIV></DIV>>offering programs towards this end.
<DIV></DIV>>
<DIV></DIV>>Thanks & Regards,
<DIV></DIV>>
<DIV></DIV>>Jay
<DIV></DIV>>
<DIV></DIV>>-----Original Message-----
<DIV></DIV>>From: bio_bulletin_board-admin@bioinformatics.org
<DIV></DIV>>[mailto:bio_bulletin_board-admin@bioinformatics.org]On Behalf
Of
<DIV></DIV>>Meredith Salisbury
<DIV></DIV>>Sent: Friday, May 10, 2002 11:34 AM
<DIV></DIV>>To: bio_bulletin_board@bioinformatics.org
<DIV></DIV>>Subject: RE: [BiO BB] PhD post in plasmid bioinformatics,
genomics and
<DIV></DIV>>ecology
<DIV></DIV>>
<DIV></DIV>>
<DIV></DIV>>Hi Dawn,
<DIV></DIV>>
<DIV></DIV>>I'm with Genome Technology magazine and saw your recent post.
I'm working
<DIV></DIV>>on an article about what kind of training people need for
bioinformatics and
<DIV></DIV>>what positions they should look for or expect, and was
wondering if I could
<DIV></DIV>>talk to you for some information about what the hiring side is
looking for.
<DIV></DIV>>
<DIV></DIV>>Thanks so much,
<DIV></DIV>>Meredith
<DIV></DIV>>
<DIV></DIV>>
<DIV></DIV>>___________________
<DIV></DIV>>Meredith Salisbury
<DIV></DIV>>Managing Editor, Genome Technology
<DIV></DIV>>+1.212.651.5635
<DIV></DIV>>
<DIV></DIV>>
<DIV></DIV>>
<DIV></DIV>> > -----Original Message-----
<DIV></DIV>> > From: bio_bulletin_board-admin@bioinformatics.org
<DIV></DIV>> > [mailto:bio_bulletin_board-admin@bioinformatics.org]On
Behalf Of Dawn
<DIV></DIV>> > Field
<DIV></DIV>> > Sent: Friday, May 10, 2002 9:50 AM
<DIV></DIV>> > To: bio_bulletin_board@bioinformatics.org
<DIV></DIV>> > Subject: [BiO BB] PhD post in plasmid bioinformatics,
genomics and
<DIV></DIV>> > ecology
<DIV></DIV>> >
<DIV></DIV>> >
<DIV></DIV>> > Dear List,
<DIV></DIV>> >
<DIV></DIV>> > We recently hired a superb research programmer following
a post
<DIV></DIV>> > he made to this list about wanting to move from staight
IT into
<DIV></DIV>> > bioinformatics - so we're making sure to post here for
this UK
<DIV></DIV>> > studentship. For more information about the
<DIV></DIV>> > bioinformatics/genomics aspects of the below studentship
please
<DIV></DIV>> > feel free to contact me.
<DIV></DIV>> >
<DIV></DIV>> >
<DIV></DIV>> > ANNOUNCEMENT
<DIV></DIV>> > A 3-year NERC funded studentship is available for
doctoral research,
<DIV></DIV>> > starting 1st October 2002, to work on the ecology and
functional
<DIV></DIV>> > genomics of plasmids,
<DIV></DIV>> > supervised by Professor Mark Bailey, Professor John Fry,
and Dr.
<DIV></DIV>> > Dawn Field.
<DIV></DIV>> >
<DIV></DIV>> > We are seeking a motivated student able to work at the
interface
<DIV></DIV>> > of genomics,
<DIV></DIV>> > bioinformatics, evolutionary and ecological genetics, and
<DIV></DIV>> > microbial adaptation to develop
<DIV></DIV>> > new approaches and methods of addressing key questions
about the
<DIV></DIV>> > role of plasmids
<DIV></DIV>> > in short and long-term ecological adaptation.
<DIV></DIV>> >
<DIV></DIV>> > To apply, please send a CV and details of two referees
(name,
<DIV></DIV>> > address, fax,
<DIV></DIV>> > and email) to Professor Mark Baily, Microbial Ecology
Section, CEH Oxford,
<DIV></DIV>> > Mansfield Rd, Oxford OX1 3SR. Applications are invited
from UK residents.
<DIV></DIV>> >
<DIV></DIV>> > The closing date for applications is the 31st May 2002.
<DIV></DIV>> >
<DIV></DIV>> >
<DIV></DIV>> > PROJECT BACKGROUND AND DESCRIPTION
<DIV></DIV>> > Ecological and functional genomic studies to determine
the
<DIV></DIV>> > evolutionary contribution
<DIV></DIV>> > of plasmids to the horizontal gene pool of bacteria
<DIV></DIV>> >
<DIV></DIV>> > The revolution in genomics has already produced 60 +
published
<DIV></DIV>> > bacterial genome
<DIV></DIV>> > sequences and over 230 plasmid sequences for comparison
and
<DIV></DIV>> > study. The study
<DIV></DIV>> > of bacterial genome sequences combined with the
introduction of
<DIV></DIV>> > large-scale population
<DIV></DIV>> > studies of DNA sequence-level variation has led to a
paradigm
<DIV></DIV>> > shift in our thinking about
<DIV></DIV>> > how fluid bacterial chromosomes are and the amounts of
<DIV></DIV>> > recombination they are able to
<DIV></DIV>> > undergo. An extremely important aspect of this fluid gene
pool
<DIV></DIV>> > that has received far
<DIV></DIV>> > less attention is the contribution of plasmids,
extrachromosomal
<DIV></DIV>> > genetic elements that
<DIV></DIV>> > persist and replicate independently of the host genome.
The
<DIV></DIV>> > significance of
<DIV></DIV>> > understanding this horizontal gene pool (HGP) lies in
attempting
<DIV></DIV>> > to understand how,
<DIV></DIV>> > when and why plasmids contribute to the evolution
fitness,
<DIV></DIV>> > persistence, and ecological
<DIV></DIV>> > role of a given host in a specific environment.
<DIV></DIV>> >
<DIV></DIV>> > For the last decade we have studied the microbial
genetics of
<DIV></DIV>> > plant associated
<DIV></DIV>> > pseudomonads and demonstrated the direct co-operation
between
<DIV></DIV>> > host and plasmid
<DIV></DIV>> > in local adaptation to the niche. Current questions we
are
<DIV></DIV>> > trying to address include:
<DIV></DIV>> > How does plasmid host-range evolve? What selective
pressures
<DIV></DIV>> > control plasmid
<DIV></DIV>> > persistence or extinction in populations? How
different/similar
<DIV></DIV>> > is the genome structure
<DIV></DIV>> > and gene content of plasmids taken from the same host?
Which
<DIV></DIV>> > plasmid genes/sequences
<DIV></DIV>> > are responsible for specific host phenotypes and
adaptation? Do
<DIV></DIV>> > rates of recombination
<DIV></DIV>> > differ within plasmids when compared to their host
chromosome?
<DIV></DIV>> > To answer these broad
<DIV></DIV>> > questions, we need to collect, analyse, and integrate
information
<DIV></DIV>> > obtained from a variety
<DIV></DIV>> > of experimental and computer-based approaches including:
1)
<DIV></DIV>> > population-level and
<DIV></DIV>> > phylogenetic studies of genetic variation found in
plasmid and
<DIV></DIV>> > host populations, 2) comparative
<DIV></DIV>> > genomics analysis of plasmids and their hosts, 3)
transcriptomic
<DIV></DIV>> > studies of plasmid genes
<DIV></DIV>> > expressed only in certain hosts/environments, and 4)
proteomic
<DIV></DIV>> > studies of host-specific
<DIV></DIV>> > and environment-specific protein profiles collected using
<DIV></DIV>> > state-of-the-art proteomic
<DIV></DIV>> > technologies.
<DIV></DIV>> >
<DIV></DIV>> > Students with undergraduate or MRes degrees (or
significant
<DIV></DIV>> > research experience) in
<DIV></DIV>> > the fields of Ecology, Evolution, Microbiology, or
Computational
<DIV></DIV>> > biology (Bioinformatics)
<DIV></DIV>> > are strongly encouraged to apply. Students with a
background in
<DIV></DIV>> > Computer Science,
<DIV></DIV>> > Maths, Statistics, or a related field with a strong
desire to
<DIV></DIV>> > learn biological principles will
<DIV></DIV>> > also be considered. The student will be located in the
<DIV></DIV>> > Laboratories of Mark Bailey
<DIV></DIV>> > (mbj@ceh.ac.uk) and Dawn Field (Dfield@ceh.ac.uk) at
CEH-Oxford
<DIV></DIV>> > and be registered
<DIV></DIV>> > for a NERC funded PhD with John Fry (fry@cardiff.ac.uk)
at the
<DIV></DIV>> > University of Cardiff.
<DIV></DIV>> >
<DIV></DIV>> >
<DIV></DIV>> >
<DIV></DIV>> >
<DIV></DIV>> >
<DIV></DIV>> > _______________________________________________
<DIV></DIV>> > BiO_Bulletin_Board maillist -
BiO_Bulletin_Board@bioinformatics.org
<DIV></DIV>> >
http://bioinformatics.org/mailman/listinfo/bio_bulletin_board
<DIV></DIV>> >
<DIV></DIV>>
<DIV></DIV>>
<DIV></DIV>>_______________________________________________
<DIV></DIV>>BiO_Bulletin_Board maillist -
BiO_Bulletin_Board@bioinformatics.org
<DIV></DIV>>http://bioinformatics.org/mailman/listinfo/bio_bulletin_board
<DIV></DIV>>
<DIV></DIV>>_______________________________________________
<DIV></DIV>>BiO_Bulletin_Board maillist -
BiO_Bulletin_Board@bioinformatics.org
<DIV></DIV>>http://bioinformatics.org/mailman/listinfo/bio_bulletin_board
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