<DIV>Hi, </DIV> <DIV>I am looking for a tool to do protein clustering. My aim is, <BR>given a set</DIV> <DIV> of protein sequences, I want an output which is sorted according to <BR>their distance from each other. Basically, clustering as 1 whole cluster <BR>(not according to their families). The basic idea is by using pairwise <BR>alignment between all the sequences, sequences with minimum distance will be <BR>assigned first and then progressively aligning the sequences on either side <BR>depending upon the distance in the pairwise alignment score. This is basically <BR>using Taylor's method or some other hierarchical clustering strategy. So for a given <BR>set of input sequences, a matrix will be constructed initially with their <BR>pairwise alignment scores and then constructing sequences from minimum <BR>distance and adding the rest of the sequences progessively
. If
some one can <BR>suggest some tool to perform this sequence ordering, it would be more timely help <BR>for me.<BR> Thanks. <BR> Regards Lavi<BR><BR></DIV><p>
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