<FONT size=2> <div>Hi, All,</div> <div> </div> <div>Does any body know any free internet-based software that can give an analysis of internal thermodynamic stability profiles for siRNA/shRNA . I need to assess the stability of the <STRONG>First Four</STRONG> nucleotides on <STRONG>either end</STRONG> of some siRNA -- perfect matched and mismatched. S-fold won't give the profile of the end nucleotides and mismatched siRNAs. Thanks very much in advance.</div> <div> </div> <div>Hongyan Wang</div> <div> </div> <div> </div></FONT><BR><BR><p>
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