[Bioclusters] Re: Help on BLAST

[Lai Loong Fong]

On Tue, 27 Aug 2002, Wim Glassee wrote:

> Hi Chris,
>
> >
> >
> > Wim,
> >
> > If you assume that the two blast target sets are non-overlapping, the
> > only scores which need to be recalculated are the e- and p- values.
> > Score and Bit Score are based soley on the alignment, substitution
> > matrix, and gap costs, plus the K and lambda parameters.  Those don't
> > change with target set size.
> >
> >   e-value = { m n 2^(bit_score) }
>
> Shouldn't this be:
>
> 	e-value = { m n 2^(-bit_score) }
>
> I think you forgot a minus. This is the equation found in the blast
> tutorial.
>
Hi Wim,
May I know which blast tutorial are you referring to here?

Lai L F