> I was amazed that I didn't think of this sooner. What does everybody here > use as a script and how do you prevent the database from being newly > formatted if a current BLAST search is running? We only update automatically, but not to the working blast db directory. Then we move the updated dbs manually to make sure it's done when it's ok to be done. (Also because we need to update it on all the nodes of the cluster). We obviously don't do it daily though, because it wouldn't be manageable that way... Elia