I apologise for mailing this query here - it appears that this subject is= =20 either discussed on mac advocacy groups (purely as a benchmark) or here=20 only. Experience has taught me to avoid the former assiduously. I have been unable to determine what precisely the licence conditions the= re=20 may be on the Apple/Genentech code. I know the original NCBI code is=20 unencumbered but there is nothing in the sources of the modified version=20 that clearly indicates whether I am entitled to change their source and=20 distribute the changes. Their site=20 (http://www.apple.com/downloads/macosx/math_science/applegenentechblast.h= tml)=20 states the licence is "freeware" but i don't know whether they mean the=20 beer or speech sense of it. I plan to make some changes that I would lik= e=20 to distribute later. Does anyone here have the links with Apple or Genentech to establish what= we=20 may do with the code? My apologies again if this is the wrong place to ask. Regards, David Huen, Dept. of Genetics, Univ. of Cambridge