With our casual, increasingly paranoid discussions revolving around Palladium (see http://www.internetnews.com/ent-news/article.php/1378731 for only one article if you haven't heard of it), I was wondering what plans biocomputing folks are making in the event that this Microsoft-led plan becomes entrenched in all hardware. Quick summary of Palladium (at least, my understanding)... Palladium resides on the hardware level. Worst-case scenario has some chip detecting "signed" hardware before booting, a "signed" operating system during boot-up, and "signed" software applications. Otherwise, details of Palladium are not yet generally available. It does, however, also tie into the plans of the TCPA (Trusted Computing Platform Alliance) - HP/Compaq, Intel, Microsoft, and IBM (probably others now also). So, various x86 linux distributions may not hold the keys to the hardware. For those running open source biocomputing software on Microsoft operating systems, I doubt the software will be "signed". If the hurdle to getting a "signature" parallels the "ease" and cost of obtaining a signed certificate from Verisign for web security, free/open source biocomputing software may be s.o.l. Any thoughts? -jennifer