Le Lundi 1 D=E9cembre 2003 18:25, Josh Goodman a =E9crit : > The NCBI has a program called fmerge which lets you merge update files > into the blast databases instead of downloading the entire set each night. > However, it doesn't handle duplication so you will need to re-download the > complete set once a month or so to flush dups out. Take a look at > ftp://ftp.ncbi.nih.gov/blast/db/README for more information. I have already looked for this programme and never found it. I had asked th= e=20 people at NCBI where it is, they said it is no more supported and that they= =20 are still working on a new tool of this kind. =46abien