andy law (RI) wrote: > but if anyone out there is prepared to > pitch in with their observations, I'll be very grateful. Hi Andy, Local caching of blast databases to avoid NFS is fine but removing NFS totally from a GridEngine setup may be overkill unless you have some other serious internal requirements/drivers for a no-filesharing deployment. A non-NFS setup will complicate your test cluster, especially in the early stages as you find yourself making constant changes to queue configurations and various SGE settings. It will also prohibit you from using the SGE failover features. The path of least resistance in this case is to go ahead with NFS avoidance techniques for your data and blast work but leave a shared filesystem in place for the sole use of (a) grid engine and (b) (possibly) writing your blast results back to a common location. I'd recommend doing this if at all possible. If you are in an environment where the shared filesystem is impossible then you can follow the NFSreduction howto that has already been posted. Let us on the list know how it goes! -Chris