We have 2 gigs of RAM per Node. For our testing purposes we are willing to add as much RAM as necessary, up to 8 is permitted on the Xserves. The IBM actually has 8 gigs in it. I'd be willing to tweak the kernel, or anything else necessary to have memory allocation work a little more effectively for BLAST if possible. We've even considered simply dedicating a machine or two to performing at its best with BLAST. Thanks Juan