Hello biocluster, some time ago, for BioDec internal use, we packaged the most recent version of hmmer (2.3.2) for the i386 and amd64 sarge release of Debian. Since it is working without any problem on our machines, and the official HMMER package included in debian is now 5 years old (release 2.1.4), we are putting our unofficial package on our public repository so that other Debian HMMER users may take advantage of it. If you are interested in having a look to what we did, you can find everything at: http://www.biodec.com/opensource/debian otherwise, put the two following lines in your /etc/apt/sources.list deb http://www.biodec.com/opensource/debian sarge main deb-src http://www.biodec.com/opensource/debian sarge main Happy HMMERing, Ivan Rossi -- Ivan Rossi, Ph.D. - info at biodec dot com BioDec S.r.l., Via Calzavecchio 20/2, I-40033 Casalecchio di Reno (BO), Italy Phone: +39-051-0548263 - web: http://www.biodec.com/Members/ivan