Andrew, How long are the read windows that you are looking for? You might be able to use blast without the gaping functions and set a window size to the length of homologous bases your looking for. Just a thought. Mark -----Original Message----- From: biodevelopers-admin at bioinformatics.org [mailto:biodevelopers-admin at bioinformatics.org] On Behalf Of Andrew Bagshaw Sent: Saturday, September 07, 2002 1:28 AM To: biodevelopers at bioinformatics.org Subject: [Biodevelopers] request for help on bioinformatics problem Hello, I am trying to find homologous pairs from among thousands of 50 bp sequences as part of my bioinformatics research. Could someone please advise if there is any software available anywhere that will do this job? Andrew Bagshaw Doctoral student in genetics University of Canterbury New Zealand _______________________________________________ Biodevelopers mailing list Biodevelopers at bioinformatics.org http://bioinformatics.org/mailman/listinfo/biodevelopers