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<P><FONT FACE="Arial">Dear Colleague,</FONT>
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<P><FONT FACE="Arial">I would like to draw your attention to the following two courses whose application deadlines will be closing on<B> </B></FONT><B><FONT COLOR="#FF0000" FACE="Arial">14th December 2008.</FONT></B></P>
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<P><B><FONT SIZE=5 FACE="Arial">Design and Analysis of Genetic-based Association Studies</FONT></B>
<BR><B><FONT SIZE=5 FACE="Arial">31 March - 4 April</FONT></B>
<BR><FONT FACE="Arial">The residential workshop will aim to give researchers involved in disease studies, a firm grounding in the use of the latest statistical methods and software used in the analysis of genetic association studies. The course will cover both theoretical and practical aspects of the design and analysis of such studies. Each topic will include a lecture followed by a practical session in which state-of-the-art statistical software will be applied to relevant datasets. The practical sessions will illustrate the ideas presented in the lectures. All the software used will be freely available so skills learnt can be applied to the datasets after the course. </FONT></P>
<P><FONT FACE="Arial">Topics covered:</FONT>
<BR><FONT FACE="Arial">Introduction to genetic association studies</FONT>
<BR><FONT FACE="Arial">Study design</FONT>
<BR><FONT FACE="Arial">Basic association analysis</FONT>
<BR><FONT FACE="Arial">Haplotype estimation</FONT>
<BR><FONT FACE="Arial">Haplotype analysis and fine mapping</FONT>
<BR><FONT FACE="Arial">Family-based association studies</FONT>
<BR><FONT FACE="Arial">Gene-gene interactions</FONT>
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<P><A HREF="http://www.wellcome.ac.uk/doc_WTX034447.html"><U><FONT COLOR="#0000FF" FACE="Arial">http://www.wellcome.ac.uk/doc_WTX034447.html</FONT></U></A>
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<P><B><FONT SIZE=5 FACE="Arial">Microarrays: Methods and Applications for Genome Analysis</FONT></B>
<BR><B><FONT SIZE=5 FACE="Arial">6 -15 April</FONT></B>
<BR><FONT FACE="Arial">The course will provide a comprehensive overview and practical experience of the production and uses of DNA microarrays for a broad range of applications. While complete details of microarray fabrication will be covered in theoretical sessions and demonstrations, the main theme of the course will be the applications of DNA microarrays for state-of-the-art transcriptome analysis as detailed below. </FONT></P>
<P><FONT FACE="Arial">Topics covered:</FONT>
<BR><FONT FACE="Arial">1, Expression analysis on whole genome oligonucleotide arrays.</FONT>
<BR><FONT FACE="Arial">2. MicroRNA Analysis</FONT>
<BR><FONT FACE="Arial">3. Array comparative genomics</FONT>
<BR><FONT FACE="Arial">4. DNA protein interactions of genomic microarrays</FONT>
<BR><FONT FACE="Arial">5. Bioinformatics and data mining</FONT>
<BR><A HREF="http://www.wellcome.ac.uk/doc_WTX026218.html"><U><FONT COLOR="#0000FF" FACE="Arial">http://www.wellcome.ac.uk/doc_WTX026218.html</FONT></U></A>
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<P><FONT FACE="Arial">Please pass this e mail onto any colleagues who maybe interested.</FONT>
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<P><FONT FACE="Arial">Best wishes,</FONT>
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<P><FONT COLOR="#000000" FACE="Arial">Dr Rebecca Twells</FONT>
<BR><FONT COLOR="#000000" FACE="Arial">Advanced Courses Programme Manager</FONT>
<BR><FONT COLOR="#000000" FACE="Arial">Wellcome Trust Advanced Courses</FONT>
<BR><FONT COLOR="#000000" FACE="Arial">Wellcome Trust Genome Campus</FONT>
<BR><FONT COLOR="#000000" FACE="Arial">Hinxton</FONT>
<BR><FONT COLOR="#000000" FACE="Arial">Cambridge</FONT>
<BR><FONT COLOR="#000000" FACE="Arial">CB10 1SA</FONT>
<BR><FONT COLOR="#000000" FACE="Arial">Tel: +44 (0)1223 496910</FONT>
<BR><FONT COLOR="#000000" FACE="Arial">Fax: +44 (0)1223 495130</FONT>
<BR><A HREF="mailto:advancedcourses@hinxton.wellcome.ac.uk"><U></U><U><FONT COLOR="#0000FF" FACE="Arial">mailto:advancedcourses@hinxton.wellcome.ac.uk</FONT></U></A>
<BR><A HREF="http://www.wellcome.ac.uk/advancedcourses"><U></U><U><FONT COLOR="#0000FF" FACE="Arial">http://www.wellcome.ac.uk/advancedcourses</FONT></U></A>
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<P><FONT FACE="Arial">If you do not wish to receive further information from Wellcome Trust Advanced Courses, please reply to this email with the word 'Unsubscribe' in the subject and the body of the text.</FONT></P>
<P><SPAN LANG="en-gb"><FONT SIZE=2 FACE="Arial">The Wellcome Trust is a charity registered in England, no. 210183. Its sole trustee is The Wellcome Trust Limited, a company registered in England, no. 2711000, whose registered office is at 215 Euston Road, London NW1 2BE, UK.</FONT></SPAN></P>
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