An enhanced version of FirstGlance in Jmol (version 0.99) is now available (http://firstglance.jmol.org). FirstGlance is free and open-source, as is the Jmol java applet upon which it is based. Major new features are: 1. There is a new Snapshot Gallery, which in effect provides a quick tour of what FirstGlance can do. http://firstglance.jmol.org/snaps/index.htm 2. "Contacts.." enables you to select any chain(s), residue(s), or atom(s) by clicking on them. It then shows you the probable non-covalent bonds to the selected moieties. The non-covalent bonds are divided into hydrogen bonds with water, water bridges, non-water hydrogen bonds, hydrophobic van der Waals interactions, cation-pi interactions, salt bridges and interactions with metals. These subsets can be shown one at a time, or in any combination. Distances and angles can be measured easily. See the Snapshot Gallery (above). 2. "Find.." lets you enter a sequence number (or range), or an amino acid name (such as PRO, CYS), or an element name. Whatever you enter is highlighted with yellow halos, making it easy to locate in the 3D structure. Gaps in protein chains (due to crystallographic disorder) can be located via a link to Wang & Dunbrack's Sequence-to-Coordinates (S2C) utility. 3. There is a new "one click" option to show all protein salt bridges and all protein cation-pi orbital interactions throughout the model (look under "More Views.."). A link to Gallivan and Dougherty's CaPTURE server provides a definitive list of energetically significant cation-pi interactions. Many other improvements were made (see list at http://firstglance.jmol.org/versions.htm). /* - - - - - - - - - - - - - - - - - - - - - - - - - - - Eric Martz, Professor Emeritus, Dept Microbiology U Mass, Amherst -- http://www.umass.edu/molvis/martz Biochem 3D Education Resources http://MolviZ.org See 3D Molecules, Install Nothing! - http://firstglance.jmol.org Protein Explorer - 3D Visualization: http://proteinexplorer.org Workshops: http://workshops.proteinexplorer.org World Index of Molecular Visualization Resources: http://molvisindex.org ConSurf - Find Conserved Patches in Proteins: http://consurf.tau.ac.il Atlas of Macromolecules: http://atlas.proteinexplorer.org PDB Lite Macromolecule Finder: http://pdblite.org Molecular Visualization EMail List (molvis-list): http://bioinformatics.org/mailman/listinfo/molvis-list - - - - - - - - - - - - - - - - - - - - - - - - - - - */