DNAstar and MacVector are two "competing" application suites for sequence analysis. They have some very nicely made GUIs. Take a look: http://www.dnastar.com/products/products.html http://www.oxmol.com/prods/macvector/work/ I wonder if DNA sequence analysis tools should be different programs from protein (or polypeptide) sequence analysis tools, or maybe a single program such as the sequence editor can switch between the two? Of course they present some very different problems...but then again...? What do you guys think? We should also consider different types of genetic maps, according to the system: chromosome vs. bacterial circular genome vs. plasmid vs. viral genome. Even proteins can be represented in several different ways: primary/sequence vs. secondary vs. tertiary vs. quarternary. I'm just thinking about whether we'll need one big tool to show these or many smaller tools. I tend to favor many small loci here. Jeff -- J.W. Bizzaro Phone: 617-552-3905 Boston College mailto:bizzaro at bc.edu Department of Chemistry http://www.uml.edu/Dept/Chem/Bizzaro/ --