Locians, Gary sent me a link to this 'paper' from NetGenics titled "NetGenics White Papers - A CORBA-Java Framework for Drug Discovery": http://www.netgenics.com/white_paper.html If you haven't heard of this product, I suggest you read this paper. Actually, if you are at all interested in the CORBA-based framework for Loci, you REALLY need to read this thoroughly! Why? Because this is almost exactly what we had in mind for Loci's infrastructure, with the exception of some different wording. Here's a SYNERGY <-> Loci translation of terms: Client == GUI interface, such as a Viewer Locus Server == Processor Locus Project Manager == Loci Daemon Analysis Manager == Loci Hub This goes to show that the use of CORBA in bioinformatics is not new, and that it doesn't take much to derive a 'framework' for data-type and language-independent analyses. I didn't find any information on pricing for SYNERGY or even screenshots. Informax's VectorNTI is another commercial application that uses a similar (although I think not CORBA-based) framework: http://www.informaxinc.com/products/vntisuite/index.html The framework may not be unique, but Loci's Workflow Diagram, project management and graphical programming language in this environment could be. How else can we improve upon this now 'common' framework? Cheers. Jeff -- +----------------------------+ | J.W. Bizzaro | | jeff at bioinformatics.org | | | | THE OPEN LAB | | Open Source Bioinformatics | | | | http://bioinformatics.org/ | +----------------------------+