[ssml] Re: Sequence defined domains?

[Dan Bolser]

<quote who="Dan Bolser">
> Hi,
>
> When defining domains based on sequence searching, do you find the 'dom-in-dom'
> type situations which are seen with structural domains?
>
> For example at the chain level
>
> --/---A-part1---/----------B---------/----A-part2----/---
>
>
> which forms two globular domains at the structural level.
>
> I guess HMM can detect this, in addition to the situation
>
> --/----------A-alone-----------/---
>
>
> Is it a part of Pfam or any other sequence based domain definition?
>
> Cheers,
> Dan.