Greetings All, I am interested in setting up a bioinformatics machine to do in-house blast & clustering with 10's to 100,000's of ESTS. How much RAM is needed to make these tasks bearable? Any experiences welcome. Cheers, Tristan -- Tristan J. Fiedler, Ph.D. Postdoctoral Research Fellow - Walsh Laboratory NIEHS Marine & Freshwater Biomedical Sciences Center Rosenstiel School of Marine & Atmospheric Sciences University of Miami tfiedler at rsmas.miami.edu t.fiedler at umiami.edu (alias) 305-361-4626