[ssml] secondary structure prediction

[Goel, Manisha]

Hi All,

 

I have recently started working on the secondary structure prediction of protein from the sequences and have a small query.

It is probably widely accepted that the center of the helix or stand is predicted more accurately than the boundaries of these elements (start and end positions). A number of studies focusing on improving the prediction of alpha-helical ends have been reported but I havn't come across any similar work for the prediction of Beta-strand ends. Is it because Beta-stand ends are already predicted with much higher accuracy than the helix ends? I havn't been able to find reference to any such comparison or observation either.  

 

Kindly point me to any such studies, if possible.

Thanks for any suggestions.

 

-Manisha