Hi, We urgently need some information regarding the time/computational complexity of HMMsearch, PSI-Blast, PHI-Blast and Mast. Are there any results available? If not, what is the difficulty in estimating the time complexity of these methods? Best Wishes & Happy new year. Intikhab Alam/ Georg Fuellen PS. We apologize if any one of you received this message twice. --- Intikhab Alam PhD Scholar International NRW Graduate School in Bioinformatics and Genome Research Center for Biotechnology (CeBiTec), University of Bielefeld Universitaetsstr. 25, D-33615 Bielefeld, Germany P: +49 (0) 521 106-4915 , F: +49 (0) 521 106-6490 E: intikhab at cebitec.uni-bielefeld.de w: http://www.cebitec.uni-bielefeld.de/~intikhab ~-_-_~GS_BiG~_-_-~