ecoli {lemma}R Documentation

The Escherichia coli data (Hung et al., 2002)

Description

The Leucine-responsive regulatory protein (Lrp) data analyzed by Hung et al. consists of 2,758 genes, with 4 replicates in each treatment group. The experimental design for the Affymetrix GeneChip experiments is as follows: four GeneChips were hybridized with biotin-labeled RNA pools 1-3, 4-6, 7-9, and 10-12 prepared from lrp+ cells, and four GeneChips were hybridized with biotin-labeled RNA pools 1-3, 4-6, 7-9, and 10-12 prepared from lrp- cells, respectively. One average difference measurement for each gene probe set on each GeneChip was obtained for subsequent data processing and analysis. The normalized data was downloaded from
http://www.jbc.org/cgi/content/full/277/43/40309/DC1 and was further transformed by taking the log2 of the responses.

Usage

ecoli

Format

A data frame containing 2,758 rows and 10 columns. The first column contains the gene IDs, the second column contains the gene names. Columns 3-6 contain the reponses for the 4 control samples, and columns 7-10 contain the reponses for the 4 treatment samples.

References

Hung, S. P., Baldi, P. & Hatfield, G. W. (2002). Global gene expression profiling in Escherichia coli K12. The effects of leucine-responsive regulatory protein. J Biol Chem 277, 40309-40323


[Package lemma version 1.2-1 Index]