npde-package {npde} | R Documentation |
Routines to compute normalised prediction distribution errors, a metric designed to evaluate non-linear mixed effect models such as those used in pharmacokinetics and pharmacodynamics
Package: | npde |
Type: | Package |
Version: | 1.0 |
Date: | 2007-01-20 |
License: | GPL version 2 or later |
See the documentation for npde or autonpde for details
Emmanuelle Comets, Karl Brendel and France Mentré
Maintainer: Emmanuelle Comets <emmanuelle.comets@bichat.inserm.fr>
K. Brendel, E. Comets, C. Laffont, C. Laveille, and F. MentrĂ©. Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide. Pharmaceutical Research, 23:2036–49, 2006.
data(theopp) data(simtheopp) # Calling autonpde with dataframes x<-autonpde(theopp,simtheopp,1,3,4,boolsave=FALSE) x$npde # Calling autonpde with names of files to be read from disk write.table(theopp,"theopp.tab",quote=FALSE,row.names=FALSE) write.table(simtheopp,"simtheopp.tab",quote=FALSE,row.names=FALSE) x<-autonpde(namobs="theopp.tab", namsim="simtheopp.tab", iid = 1, ix = 3, iy = 4, boolsave = FALSE) x$npde