Basic Information | |||
Gene ID | 100348778 | ||
Gene Name | STAT3 | ||
Full Name | Signal transducer and activator of transcription | ||
Organism | Oryctolagus cuniculus [9986] |
Cross Reference | |||
UniProt | G1T0H3 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSOCUP00000009494 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 467 | 588 | 3.80e-59 | EF-hand domain pair |
ENSOCUP00000009494 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 1 | 120 | 1.10e-45 | STAT transcription factor, protein interaction |
ENSOCUP00000009494 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 139 | 321 | 1.40e-72 | STAT transcription factor, all-alpha |
ENSOCUP00000009494 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 322 | 466 | 6.00e-66 | STAT transcription factor, DNA-binding, subdomain |
ENSOCUP00000009494 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 589 | 719 | 1.80e-51 | SH2 domain |
ENSOCUP00000009494 | PANTHER | PTHR11801 | IPR001217 | 2 | 771 | 0.00e-00 | Transcription factor STAT |
ENSOCUP00000009494 | Pfam | PF00017 | IPR000980 | 584 | 674 | 3.70e-13 | SH2 domain |
ENSOCUP00000009494 | Pfam | PF01017 | IPR013800 | 139 | 319 | 3.70e-59 | STAT transcription factor, all-alpha |
ENSOCUP00000009494 | Pfam | PF02864 | IPR013801 | 321 | 574 | 2.90e-127 | STAT transcription factor, DNA-binding |
ENSOCUP00000009494 | Pfam | PF02865 | IPR013799 | 2 | 121 | 8.50e-42 | STAT transcription factor, protein interaction |
ENSOCUP00000009494 | ProSiteProfiles | PS50001 | IPR000980 | 580 | 670 | 0.00e-00 | SH2 domain |
ENSOCUP00000009494 | SMART | SM00252 | IPR000980 | 582 | 663 | 1.50e-03 | SH2 domain |
ENSOCUP00000009494 | SMART | SM00964 | IPR013799 | 2 | 122 | 1.80e-64 | STAT transcription factor, protein interaction |
ENSOCUP00000009494 | SUPERFAMILY | SSF47655 | IPR015988 | 136 | 321 | 0.00e-00 | STAT transcription factor, coiled coil |
ENSOCUP00000009494 | SUPERFAMILY | SSF48092 | IPR013799 | 1 | 120 | 0.00e-00 | STAT transcription factor, protein interaction |
ENSOCUP00000009494 | SUPERFAMILY | SSF49417 | IPR008967 | 322 | 575 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSOCUP00000009494 | PF01017 | 0 | STAT_alpha | STAT protein, all-alpha domain |
ENSOCUP00000009494 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
ENSOCUP00000009494 | PF02865 | 8.50028e-42 | STAT_int | STAT protein, protein interaction domain |
ENSOCUP00000009494 | PF00017 | 1.4e-13 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSOCUP00000009494 | GO:0001659 | biological_process | temperature homeostasis |
ENSOCUP00000009494 | GO:0001754 | biological_process | eye photoreceptor cell differentiation |
ENSOCUP00000009494 | GO:0006357 | biological_process | regulation of transcription from RNA polymerase II promoter |
ENSOCUP00000009494 | GO:0019953 | biological_process | sexual reproduction |
ENSOCUP00000009494 | GO:0042593 | biological_process | glucose homeostasis |
ENSOCUP00000009494 | GO:0042755 | biological_process | eating behavior |
ENSOCUP00000009494 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
ENSOCUP00000009494 | GO:0060397 | biological_process | JAK-STAT cascade involved in growth hormone signaling pathway |
ENSOCUP00000009494 | GO:0005634 | cellular_component | nucleus |
ENSOCUP00000009494 | GO:0005737 | cellular_component | cytoplasm |
ENSOCUP00000009494 | GO:0005886 | cellular_component | plasma membrane |
ENSOCUP00000009494 | GO:0003677 | molecular_function | DNA binding |
ENSOCUP00000009494 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSOCUP00000009494 | GO:0004871 | molecular_function | signal transducer activity |
ENSOCUP00000009494 | GO:0005509 | molecular_function | calcium ion binding |
ENSOCUP00000009494 | GO:0019901 | molecular_function | protein kinase binding |
ENSOCUP00000009494 | GO:0043565 | molecular_function | sequence-specific DNA binding |
ENSOCUP00000009494 | GO:0046983 | molecular_function | protein dimerization activity |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
31033 | Takifugu rubripes | 101070968 | 10020 | Dipodomys ordii | ENSDORG00000000308 |
30608 | Microcebus murinus | ENSMICG00000012015 | 13735 | Pelodiscus sinensis | ENSPSIG00000015868 |
9739 | Tursiops truncatus | ENSTTRG00000007163 | 10029 | Cricetulus griseus | 100755865 |
9597 | Pan paniscus | 100987766 | 9555 | Papio anubis | 100998929 |
39432 | Saimiri boliviensis | 101049662 | 9685 | Felis catus | 101095698 |
8083 | Xiphophorus maculatus | 102226045 | 9615 | Canis familiaris | 490967 |
28377 | Anolis carolinensis | ENSACAG00000017940 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000006266 |
9358 | Choloepus hoffmanni | ENSCHOG00000009349 | 9483 | Callithrix jacchus | ENSCJAG00000000409 |
10141 | Cavia porcellus | ENSCPOG00000007939 | 9361 | Dasypus novemcinctus | ENSDNOG00000001471 |
9796 | Equus caballus | ENSECAG00000016439 | 69293 | Gasterosteus aculeatus | ENSGACG00000008607 |
9595 | Gorilla gorilla | ENSGGOG00000017110 | 8049 | Gadus morhua | ENSGMOG00000014955 |
7897 | Latimeria chalumnae | ENSLACG00000012019 | 9785 | Loxodonta africana | ENSLAFG00000014062 |
9315 | Macropus eugenii | ENSMEUG00000006663 | 9103 | Meleagris gallopavo | ENSMGAG00000003545 |
59463 | Myotis lucifugus | ENSMLUG00000017449 | 9544 | Macaca mulatta | ENSMMUG00000010707 |
13616 | Monodelphis domestica | ENSMODG00000028212 | 9669 | Mustela putorius furo | ENSMPUG00000010509 |
9258 | Ornithorhynchus anatinus | ENSOANG00000031491 | 30611 | Otolemur garnettii | ENSOGAG00000001517 |
8128 | Oreochromis niloticus | ENSONIG00000001148 | 9978 | Ochotona princeps | ENSOPRG00000008362 |
8090 | Oryzias latipes | ENSORLG00000004061 | 9813 | Procavia capensis | ENSPCAG00000010265 |
9601 | Pongo abelii | ENSPPYG00000008392 | 132908 | Pteropus vampyrus | ENSPVAG00000003885 |
42254 | Sorex araneus | ENSSARG00000014231 | 9305 | Sarcophilus harrisii | ENSSHAG00000014833 |
43179 | Ictidomys tridecemlineatus | ENSSTOG00000006741 | 59729 | Taeniopygia guttata | ENSTGUG00000002600 |
9478 | Tarsius syrichta | ENSTSYG00000012448 | 8364 | Xenopus tropicalis | ENSXETG00000007642 |