Basic Information
Gene ID 100348778
Gene Name STAT3
Full Name Signal transducer and activator of transcription
Organism Oryctolagus cuniculus [9986]

Cross Reference
UniProt G1T0H3 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOCUP00000009494 Gene3D G3DSA:1.10.238.10 IPR011992 467 588 3.80e-59 EF-hand domain pair
ENSOCUP00000009494 Gene3D G3DSA:1.10.532.10 IPR013799 1 120 1.10e-45 STAT transcription factor, protein interaction
ENSOCUP00000009494 Gene3D G3DSA:1.20.1050.20 IPR013800 139 321 1.40e-72 STAT transcription factor, all-alpha
ENSOCUP00000009494 Gene3D G3DSA:2.60.40.630 IPR012345 322 466 6.00e-66 STAT transcription factor, DNA-binding, subdomain
ENSOCUP00000009494 Gene3D G3DSA:3.30.505.10 IPR000980 589 719 1.80e-51 SH2 domain
ENSOCUP00000009494 PANTHER PTHR11801 IPR001217 2 771 0.00e-00 Transcription factor STAT
ENSOCUP00000009494 Pfam PF00017 IPR000980 584 674 3.70e-13 SH2 domain
ENSOCUP00000009494 Pfam PF01017 IPR013800 139 319 3.70e-59 STAT transcription factor, all-alpha
ENSOCUP00000009494 Pfam PF02864 IPR013801 321 574 2.90e-127 STAT transcription factor, DNA-binding
ENSOCUP00000009494 Pfam PF02865 IPR013799 2 121 8.50e-42 STAT transcription factor, protein interaction
ENSOCUP00000009494 ProSiteProfiles PS50001 IPR000980 580 670 0.00e-00 SH2 domain
ENSOCUP00000009494 SMART SM00252 IPR000980 582 663 1.50e-03 SH2 domain
ENSOCUP00000009494 SMART SM00964 IPR013799 2 122 1.80e-64 STAT transcription factor, protein interaction
ENSOCUP00000009494 SUPERFAMILY SSF47655 IPR015988 136 321 0.00e-00 STAT transcription factor, coiled coil
ENSOCUP00000009494 SUPERFAMILY SSF48092 IPR013799 1 120 0.00e-00 STAT transcription factor, protein interaction
ENSOCUP00000009494 SUPERFAMILY SSF49417 IPR008967 322 575 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOCUP00000009494 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSOCUP00000009494 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSOCUP00000009494 PF02865 8.50028e-42 STAT_int STAT protein, protein interaction domain
ENSOCUP00000009494 PF00017 1.4e-13 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOCUP00000009494 GO:0001659 biological_process temperature homeostasis
ENSOCUP00000009494 GO:0001754 biological_process eye photoreceptor cell differentiation
ENSOCUP00000009494 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSOCUP00000009494 GO:0019953 biological_process sexual reproduction
ENSOCUP00000009494 GO:0042593 biological_process glucose homeostasis
ENSOCUP00000009494 GO:0042755 biological_process eating behavior
ENSOCUP00000009494 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSOCUP00000009494 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSOCUP00000009494 GO:0005634 cellular_component nucleus
ENSOCUP00000009494 GO:0005737 cellular_component cytoplasm
ENSOCUP00000009494 GO:0005886 cellular_component plasma membrane
ENSOCUP00000009494 GO:0003677 molecular_function DNA binding
ENSOCUP00000009494 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOCUP00000009494 GO:0004871 molecular_function signal transducer activity
ENSOCUP00000009494 GO:0005509 molecular_function calcium ion binding
ENSOCUP00000009494 GO:0019901 molecular_function protein kinase binding
ENSOCUP00000009494 GO:0043565 molecular_function sequence-specific DNA binding
ENSOCUP00000009494 GO:0046983 molecular_function protein dimerization activity