Basic Information | |||
Gene ID | 31 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | ACACA; ACAC, ACC1, ACCA | ||
Full Name | Acetyl-CoA carboxylase 1 | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | Q13085 | UniGene | Hs.160556 |
PDB | 4ASI | OMIM | 613933 |
KEGG | hsa:31 | UCSC | uc002hno.3 |
Protein Interactions | |
DIP | DIP-36122N |
IntAct | Q13085 |
MINT | MINT-1415014 |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_942131 | Gene3D | G3DSA:3.30.1490.20 | IPR013815 | 328 | 388 | 9.10e-22 | ATP-grasp fold, subdomain 1 |
NP_942131 | Gene3D | G3DSA:3.30.470.20 | IPR013816 | 390 | 655 | 3.10e-102 | ATP-grasp fold, subdomain 2 |
NP_942131 | Gene3D | G3DSA:3.40.50.20 | IPR016185 | 155 | 294 | 4.00e-45 | Pre-ATP-grasp domain |
NP_942131 | Pfam | PF00289 | IPR005481 | 155 | 274 | 4.00e-27 | Carbamoyl-phosphate synthase, large subunit, N-terminal |
NP_942131 | Pfam | PF00364 | IPR000089 | 790 | 855 | 4.90e-16 | Biotin/lipoyl attachment |
NP_942131 | Pfam | PF01039 | IPR000022 | 1706 | 2259 | 5.00e-175 | Carboxyl transferase |
NP_942131 | Pfam | PF02785 | IPR005482 | 545 | 651 | 1.50e-21 | Biotin carboxylase, C-terminal |
NP_942131 | Pfam | PF02786 | IPR005479 | 325 | 508 | 5.70e-54 | Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain |
NP_942131 | Pfam | PF08326 | IPR013537 | 856 | 1606 | 2.90e-251 | Acetyl-CoA carboxylase, central domain |
NP_942131 | ProSitePatterns | PS00188 | IPR001882 | 813 | 830 | - | Biotin-binding site |
NP_942131 | ProSitePatterns | PS00866 | IPR005479 | 343 | 357 | - | Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain |
NP_942131 | ProSitePatterns | PS00867 | IPR005479 | 472 | 479 | - | Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain |
NP_942131 | ProSiteProfiles | PS50968 | IPR000089 | 789 | 855 | 0.00e-00 | Biotin/lipoyl attachment |
NP_942131 | ProSiteProfiles | PS50975 | IPR011761 | 312 | 503 | 0.00e-00 | ATP-grasp fold |
NP_942131 | ProSiteProfiles | PS50979 | IPR011764 | 154 | 655 | 0.00e-00 | Biotin carboxylation domain |
NP_942131 | ProSiteProfiles | PS50980 | IPR011762 | 1735 | 1915 | 0.00e-00 | Acetyl-coenzyme A carboxyltransferase, N-terminal |
NP_942131 | ProSiteProfiles | PS50989 | IPR011763 | 1916 | 2231 | 0.00e-00 | Acetyl-coenzyme A carboxyltransferase, C-terminal |
NP_942131 | SMART | SM00878 | IPR005482 | 544 | 651 | 1.10e-28 | Biotin carboxylase, C-terminal |
NP_942131 | SUPERFAMILY | SSF51230 | IPR011053 | 782 | 854 | 0.00e-00 | Single hybrid motif |
NP_942131 | SUPERFAMILY | SSF51246 | IPR011054 | 539 | 653 | 0.00e-00 | Rudiment single hybrid motif |
NP_942131 | SUPERFAMILY | SSF52440 | IPR016185 | 129 | 277 | 0.00e-00 | Pre-ATP-grasp domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_942131 | PF01039 | 0 | Carboxyl_trans | Carboxyl transferase domain |
NP_942131 | PF02786 | 0 | CPSase_L_D2 | Carbamoyl-phosphate synthase L chain, ATP binding domain |
NP_942131 | PF08326 | 0 | ACC_central | Acetyl-CoA carboxylase, central region |
NP_942131 | PF00289 | 1.8e-27 | CPSase_L_chain | Carbamoyl-phosphate synthase L chain, N-terminal domain |
NP_942131 | PF02785 | 3.1e-22 | Biotin_carb_C | Biotin carboxylase C-terminal domain |
NP_942131 | PF00364 | 1.5e-16 | Biotin_lipoyl | Biotin-requiring enzyme |
NP_942131 | PF13535 | 9.4e-15 | ATP-grasp_4 | ATP-grasp domain |
NP_942131 | PF15632 | 5.8e-10 | ATPgrasp_Ter | ATP-grasp in the biosynthetic pathway with Ter operon |
NP_942131 | PF07478 | 2.1e-06 | Dala_Dala_lig_C | D-ala D-ala ligase C-terminus |
NP_942131 | PF02222 | 1.4e-05 | ATP-grasp | ATP-grasp domain |
NP_942131 | PF02655 | 5.9e-05 | ATP-grasp_3 | ATP-grasp domain |
NP_942131 | PF08443 | 0.00079 | RimK | RimK-like ATP-grasp domain |