>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 99.4 bits (247), Expect = 7e-27 Identities = 72/269 (26%), Positives = 120/269 (44%), Gaps = 21/269 (7%) Query: 13 LENKLIIITGAGGVLCSFLAKQLAYTKANIALLDLNFEAADKAAKEINQSGGKAKAYKTN 72 +E K+ ITGA + +A+ LA A+IA +D N E +K + A+A+ + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 73 VLELENIKEVRDQIAIDFGTCDILINGAGGNNPKATTDNEFHQFDLNETTRTFFDLDKSG 132 V + I E+ +I + G DIL+N AG P H L Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLI-----HS------------LSDEE 108 Query: 133 IEFVFNLNYLGSLLPTQVFSKDMLGKQGANIINISSMNAFTPLTKIPAYSGAKAAISNFT 192 E F++N G ++ SK M+ ++ +I+ + S A P T + AY+ +KAA FT Sbjct: 109 WEATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFT 168 Query: 193 QWLAVYFSKVGIRCNAIAPGFLVSNQNRTLLFDTEGKP---TDRANKILTNTPMGRFGES 249 + L + ++ IRCN ++PG ++ +L D G T P+ + + Sbjct: 169 KCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKP 228 Query: 250 EELLGALLFLIDENYSAFVNGVVLPVDGG 278 ++ A+LFL+ + + L VDGG Sbjct: 229 SDIADAVLFLVSGQ-AGHITMHNLCVDGG 256
>PF06580#Sensor histidine kinase Length = 349 Score = 27.1 bits (60), Expect = 0.039 Identities = 20/125 (16%), Positives = 37/125 (29%), Gaps = 8/125 (6%) Query: 39 SVLRYFFDSGIAFSEEFSRICFVYMIFFGIILVAKDKAHLTVEIIISALPEQYRKIVLIV 98 L F + + S + + F I +++ L +I+L V Sbjct: 23 YTLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMG--QIILRV 80 Query: 99 ANICVLIAMIFIAYGALQLMSLTYTQQMPATGISSSFL------YLAAVISAVSYFFIVM 152 CV+I M++ L + P L + + ++ YF Sbjct: 81 LPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHF 140 Query: 153 FSMIK 157 F K Sbjct: 141 FKNYK 145
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 31.3 bits (71), Expect = 0.006 Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 22/105 (20%) Query: 190 AIPILVDILEQRLEYAKSLGIEH--IVNPHKEDD----IK-RIK----EITSGRMAEVVM 238 + + D + +Y K L + I +KE + IK + + EI S M E V Sbjct: 196 VVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQFHQEIQSRNMRENVK 255 Query: 239 EASGANISIKNTLHYTSFAGRIALTGWPKTETPLPTNLITFKELN 283 +S + + N H I + + + ETPLP L+TFK + Sbjct: 256 RSS---VVVANPTHIA-----IGI-LYKRGETPLP--LVTFKYTD 289
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 396 bits (1018), Expect = e-142 Identities = 186/284 (65%), Positives = 228/284 (80%) Query: 3 IQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEE 62 +++ R+ +I A L V A P+ L ++K +E QL RVG IE+DL SG+ L ++R +E Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE 60 Query: 63 RFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS 122 RFPMMSTFKV+LCGAVL+RVDAG EQL R+IHY Q DLV+YSPV+EKHL DGMTV ELC+ Sbjct: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA 120 Query: 123 AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA 182 AAITMSDN+AANLLL T+GGP LTAFL +GD+VTRLDRWE ELNEA+P D RDTT PA Sbjct: 121 AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA 180 Query: 183 AMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG 242 +MA TLRKLLT + L+ S++QL+ WM D+VAGPL+RS LPAGWFIADK+GAGERG+RG Sbjct: 181 SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARG 240 Query: 243 IIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 286 I+A LGP+ K RIVVIY + A+M ERN+QIA IGA+LI+HW Sbjct: 241 IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHW 284
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 28.0 bits (62), Expect = 0.024 Identities = 12/35 (34%), Positives = 16/35 (45%), Gaps = 5/35 (14%) Query: 142 TYKAGAITEMGRKCYV-----YWDFVAYDDDGNEI 171 Y +G I + YV WD + YDD G E+ Sbjct: 462 EYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEV 496
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.4 bits (79), Expect = 7e-04 Identities = 12/44 (27%), Positives = 21/44 (47%), Gaps = 4/44 (9%) Query: 16 PAQVIHSGNAVNQVAILGEEYVGMRPSMKVREGDVVKKGQVLFE 59 ++ HSG + I + + V+EG+ V+KG VL + Sbjct: 87 NGKLTHSGRSKEIKPIEN----SIVKEIIVKEGESVRKGDVLLK 126
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 29.0 bits (65), Expect = 0.031 Identities = 10/38 (26%), Positives = 17/38 (44%), Gaps = 1/38 (2%) Query: 405 FVYFGAVRSGNVVWNFADTVMAVMAIINLIAILMLSPI 442 A RS + W A V +A ++A+ L+P+ Sbjct: 23 DKLAAAERSKKLAWVVA-GVAGALATAGVVAVAALTPL 59
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 170 bits (431), Expect = 1e-56 Identities = 71/171 (41%), Positives = 100/171 (58%), Gaps = 4/171 (2%) Query: 1 MFDIGFSELILLMVLGLVVLGPKRLPIAIRTVMDWVKTIRGLAANVQNELKQELKLQELQ 60 MFDIGFSEL+L+ ++GLVVLGP+RLP+A++TV W++ +R LA VQNEL QELKLQE Q Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQ 60 Query: 61 DSIKKAESLNLQALSPELSKTVEELKAQADKMK----AELEDKAAQAGTTVEDQIKEIKN 116 DS+KK E +L L+PEL +++EL+ A+ MK A +KA+ T+ + + + Sbjct: 61 DSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPEKASDEAHTIHNPVVKDNE 120 Query: 117 AAENAEKPQNAISVEEAAETLSEAEKTPTDLTALETHEKVELNTHLSSYYP 167 AA P A + + E E P A + K + SS P Sbjct: 121 AAHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKTAAPSPSSSDKP 171
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 176 bits (447), Expect = 1e-54 Identities = 82/350 (23%), Positives = 152/350 (43%), Gaps = 37/350 (10%) Query: 1 MAILVTGGAGYIGSHTVVELLNAGKEVVVLDNLCNSSPKSLE--RVKQITGKEAKFYEGD 58 M LVTG AG+IG H LL AG +VV +DNL + SL+ R++ + +F++ D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 59 ILDRALLQKIFAENEINSVIHFAGLKAVGESVQKPTEYYMNNVAGTLVLIQEMKKAGVWN 118 + DR + +FA V AV S++ P Y +N+ G L +++ + + + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 119 FVFSSSATVYGDPKIIPITEDCEVGGTTNPYGTSKYMVEQILCDTAKAEPKFSMTILRYF 178 +++SS++VYG + +P + D V + Y +K E ++ T T LR+F Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE-LMAHTYSHLYGLPATGLRFF 179 Query: 179 NPVGAHESGLIGEDPNGIPNNLLP-YISQVAIGKLAQLSVFGSDYDTHDGTGVRDYIHVV 237 G P G P+ L + + GK + V+ G RD+ ++ Sbjct: 180 TVYG----------PWGRPDMALFKFTKAMLEGK--SIDVYN------YGKMKRDFTYID 221 Query: 238 DLAVGHLKALQ---------------RHENDAGLHIYNLGTGHGYSVLDMVKAFEKANNI 282 D+A ++ + A +YN+G ++D ++A E A I Sbjct: 222 DIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI 281 Query: 283 TIAYKLVERRAGDIATCYSDPSLAAKELGWVAERGLEKMMQDTWNWQKNN 332 ++ + GD+ +D + +G+ E ++ +++ NW ++ Sbjct: 282 EAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 107 bits (269), Expect = 6e-31 Identities = 37/117 (31%), Positives = 54/117 (46%), Gaps = 8/117 (6%) Query: 42 ADLQQRYNT----VYFGFDKYDITGEYVQILDAHAAYLNAT--PAAKVLVEGNTDERGTP 95 ++Q ++ T V F F+K + E LD + L+ V+V G TD G+ Sbjct: 208 PEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSD 267 Query: 96 EYNIALGQRRADAVKGYLAGKGVDAGKLGTVSYGEEKPAVLGHDEAAYSKNRRAVLA 152 YN L +RRA +V YL KG+ A K+ GE P V G+ K R A++ Sbjct: 268 AYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNP-VTGN-TCDNVKQRAALID 322
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 64.7 bits (157), Expect = 4e-13 Identities = 31/190 (16%), Positives = 65/190 (34%), Gaps = 3/190 (1%) Query: 77 QKRPEPVVEEKPPEPNQEEIKHQQEVQRQEEIKHQQEVQRQEELKRQQEQQRQQEIKKQQ 136 +KR + V PN + EEI E + + + + Sbjct: 986 EKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK 1045 Query: 137 EQARQEALEKQKQAE-EARAKQAAEAAKLKADAEAKRLAAAAKQAEEEAKAKAAEIAAQK 195 ++++ +Q E A+ ++ A+ AK A + A+ E + + E + Sbjct: 1046 QESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT-NEVAQSGSETKETQTTE-TKET 1103 Query: 196 AKQEAETKAKLEAEAKAKAAAEAKAKAEAEAKAKAAAEAKAKAEAEAKAKAAAEAKAKAD 255 A E E KAK+E E + + + +++ A E +++ + Sbjct: 1104 ATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTN 1163 Query: 256 AEAKAKAAAE 265 A + A+ Sbjct: 1164 TTADTEQPAK 1173 Score = 52.4 bits (125), Expect = 2e-09 Identities = 30/239 (12%), Positives = 70/239 (29%), Gaps = 10/239 (4%) Query: 43 EGEGDVIGAVIVDTGTAAQEWGRIQQQKKGQADKQKRPEPVVEEKPPEPNQEEIKHQQEV 102 E + + T Q + + PV P P++ + Sbjct: 986 EKRNQTVDTTNITTPNNIQA-DVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENS 1044 Query: 103 QRQEEIKHQQEVQRQEELKRQQEQQRQQEIKKQQEQARQEALEKQKQAEEARAKQAAEAA 162 +++ + + E E + +E ++ + + E + + +E + + E A Sbjct: 1045 KQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETA 1104 Query: 163 KLKADAEAKRLAAAAKQAEEEAKAKAAEIAAQ-KAKQEAETKAKLEAEAKAKAAAEAKAK 221 ++ + +AK E E + ++ +Q KQE + +AE + K Sbjct: 1105 TVEKEEKAK--------VETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK 1156 Query: 222 AEAEAKAKAAAEAKAKAEAEAKAKAAAEAKAKADAEAKAKAAAEAKAAAEAKRKADQAS 280 A + E + + + E A + + S Sbjct: 1157 EPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSES 1215 Score = 52.0 bits (124), Expect = 4e-09 Identities = 29/183 (15%), Positives = 56/183 (30%), Gaps = 9/183 (4%) Query: 110 HQQEVQRQEELKRQQEQQRQQEIKKQQEQARQEALEKQKQAEEARAKQAAEAAKLKA-DA 168 + EV+++ + I+ E AR +A A + Sbjct: 981 YNPEVEKRNQTVDTTNITTPNNIQADVPS------VPSNNEEIARVDEAPVPPPAPATPS 1034 Query: 169 EAKRLAAAAKQAEEEAKAKAAEIAAQKAKQ--EAETKAKLEAEAKAKAAAEAKAKAEAEA 226 E A + E + K + A + Q E +AK +A + A++ +E + Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKE 1094 Query: 227 KAKAAAEAKAKAEAEAKAKAAAEAKAKADAEAKAKAAAEAKAAAEAKRKADQASLDDFFN 286 + A E E KAK E + + + ++ + D N Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVN 1154 Query: 287 GGD 289 + Sbjct: 1155 IKE 1157 Score = 49.7 bits (118), Expect = 2e-08 Identities = 35/234 (14%), Positives = 66/234 (28%), Gaps = 17/234 (7%) Query: 56 TGTAAQEWGRIQQQKKGQADKQKRPEPVVEEKPPE--PNQEEIKHQQEVQRQ-EEIKHQQ 112 T T A+ + + + E E N + EV + E K Q Sbjct: 1037 TETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQ 1096 Query: 113 EVQRQEELKRQQEQQRQQEIKKQQEQARQEALEK---------QKQAEEARAKQAAEAAK 163 + +E ++E++ + E +K QE + + Q QAE AR K Sbjct: 1097 TTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK 1156 Query: 164 LKADAEAKRLAAAAKQAEEEAKAKAAEIAAQ----KAKQEAETKAKLEAEAKAKAAAEAK 219 + ++ A + A+E + + E Sbjct: 1157 -EPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSES 1215 Query: 220 AKAEAEAKAKAAAEAKAKAEAEAKAKAAAEAKAKADAEAKAKAAAEAKAAAEAK 273 + ++ E + A D + A + A A+A+ Sbjct: 1216 SNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQ 1269 Score = 32.3 bits (73), Expect = 0.004 Identities = 25/188 (13%), Positives = 55/188 (29%), Gaps = 11/188 (5%) Query: 57 GTAAQEWGRIQQQKKGQAD---KQKRPEPVVEEKPPEPNQEEIKHQQEVQRQEEIKHQQE 113 A E + Q+ K + KQ++ E V + P + + +E Q Q E Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTE 1169 Query: 114 VQRQE-------ELKRQQEQQRQQEIKKQQEQARQEALEKQKQAEEARAKQAAEAAKLKA 166 +E + + + E + +E + + +++ Sbjct: 1170 QPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRS 1229 Query: 167 DAEAKRLAA-AAKQAEEEAKAKAAEIAAQKAKQEAETKAKLEAEAKAKAAAEAKAKAEAE 225 A ++ A +A KA+ A KA ++ ++ E Sbjct: 1230 VPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMN 1289 Query: 226 AKAKAAAE 233 + + Sbjct: 1290 NEGQYNVW 1297
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 280 bits (719), Expect = 9e-94 Identities = 99/338 (29%), Positives = 164/338 (48%), Gaps = 37/338 (10%) Query: 15 FIVQSEAMKSAVENAKRFAMFDVPLLIQGETGTGKDLLAKACHYQSLRRDKKFIAVNCAG 74 + +S AM+ R D+ L+I GE+GTGK+L+A+A H RR+ F+A+N A Sbjct: 139 LVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAA 198 Query: 75 LPDEDAESEMFGRKVG-----DSETIGFFEYANEGTVLLDGIAELSLGLQAKLLRFLTDG 129 +P + ESE+FG + G + + G FE A GT+ LD I ++ + Q +LLR L G Sbjct: 199 IPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQG 258 Query: 130 SFRRVGEEKEHYANVRVICTSQVPLHLLVEQGKVRADLFHRLNVLTLNVPPLRERMTDIE 189 + VG ++VR++ + L + QG R DL++RLNV+ L +PPLR+R DI Sbjct: 259 EYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIP 318 Query: 190 PLAQGFLQEISEELKIAKPTFDKDFLLYLQKYDWKGNVRELYNTLYRACSLVQDNHLTIE 249 L + F+Q+ +E K FD++ L ++ + W GNVREL N + R +L + +T E Sbjct: 319 DLVRHFVQQAEKEGLDVK-RFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITRE 377 Query: 250 -------------------------SLNLAPPQSAVISLDEFGN-----KTLDEIIGSYE 279 S++ A ++ FG+ D ++ E Sbjct: 378 IIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEME 437 Query: 280 AQVLKLFYAEYPSTR-KLAQRLGVSHTAIANKLKQYGI 316 ++ + K A LG++ + K+++ G+ Sbjct: 438 YPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.3 bits (63), Expect = 0.049 Identities = 20/128 (15%), Positives = 46/128 (35%), Gaps = 28/128 (21%) Query: 136 GVIEALRALRPEARFLELVHRLDRDTSGILLIAKKRSALRNLHEQLRVKTVQKDYLALVR 195 I L E +++E V+ L S + + S + + + + V + + + Sbjct: 247 QAIAKHAVLEQENKYVEAVNELRVYKSQL---EQIESEILSA--KEEYQLVTQLFKNEIL 301 Query: 196 GQWQSHIKVIQAPLLKNELSSGERIVRVSEQGKPSETRFSIEERYINATLVKASPVTGRT 255 + + Q L+ + + E+ + S R +PV+ + Sbjct: 302 DKLR------QTTDNIGLLT--LELAKNEERQQASVIR---------------APVSVKV 338 Query: 256 HQIRVHTQ 263 Q++VHT+ Sbjct: 339 QQLKVHTE 346
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 34.9 bits (80), Expect = 7e-06 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 5/72 (6%) Query: 4 GGDVKADQETSGSRSIKRIGFG--FIGGIGYDITPNITLDLDYRY-NDWGRLE--NVRFK 58 G +AD +++ G F GG+ Y ITP I L+Y++ N+ G R Sbjct: 120 GMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPD 179 Query: 59 THEASFGVRYRF 70 S GV YRF Sbjct: 180 NGMLSLGVSYRF 191
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.0 bits (80), Expect = 0.002 Identities = 21/102 (20%), Positives = 31/102 (30%), Gaps = 4/102 (3%) Query: 937 RDGVEKDKRALEIEEMQLREAKKDLTEELEILEAGLFARVRNLLISSGADAAQLDKVDRT 996 + +EK K L E L A A + L GA + Sbjct: 192 QAELEKALEGAMNFSTADSAKIKTLEAEKAALAARK-ADLEKAL--EGAMNFSTADSAKI 248 Query: 997 KWLEQTIAD-EEKQNQLEQLAEQYEELRKEFEHKLEVKRKKI 1037 K LE A E +Q +LE+ E K++ + Sbjct: 249 KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 290
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1045 bits (2703), Expect = 0.0 Identities = 362/575 (62%), Positives = 436/575 (75%), Gaps = 8/575 (1%) Query: 1 MALTISRAQYVATYGPTVGDKVRLGDTNLWATIEQDLLTKGDECKFGGGKSVRDGMAQSG 60 M+ +SRA Y +GPTVGDKVRL DT L+ +E+D T G+E KFGGGK +RDGM QS Sbjct: 1 MSYRMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQS- 59 Query: 61 TATRDNPNVLDFVITNVMIIDAKLGIIKADIGIRDGRIVGIGQAGNPDTMDNVTPNMIIG 120 TR+ +D VITN +I+D GI+KADIG++DGRI IG+AGNPD V +I+G Sbjct: 60 QVTREG-GAVDTVITNALILDH-WGIVKADIGLKDGRIAAIGKAGNPDMQPGV--TIIVG 115 Query: 121 ASTEVHNGAHLIATAGGIDTHIHFICPQQAQHAIESGVTTLIGGGTGPADGTHATTCTPG 180 TEV G I TAGG+D+HIHFICPQQ + A+ SG+T ++GGGTGPA GT ATTCTPG Sbjct: 116 PGTEVIAGEGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPG 175 Query: 181 AWYMERMFQAAEALPVNVGFFGKGNCSTLDPLREQIEAGALGLKIHEDWGATPAVIDSAL 240 W++ RM +AA+A P+N+ F GKGN S L E + GA LK+HEDWG TPA ID L Sbjct: 176 PWHIARMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCL 235 Query: 241 KVADEMDIQVAIHTDTLNESGFLEDTMKAIDGRVIHTFHTEGAGGGHAPDIIKAAMYSNV 300 VADE D+QV IHTDTLNESGF+EDT+ AI GR IH +HTEGAGGGHAPDII+ NV Sbjct: 236 SVADEYDVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNV 295 Query: 301 LPASTNPTRPFTKNTIDEHLDMLMVCHHLDKRVPEDVAFADSRIRPETIAAEDILHDMGV 360 +P+STNPTRP+T NT+ EHLDMLMVCHHL +PED+AFA+SRIR ETIAAEDILHD+G Sbjct: 296 IPSSTNPTRPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGA 355 Query: 361 FSIMSSDSQAMGRIGEVVIRTWQTADKMKMQRGELGNE--GNDNFRIKRYIAKYTINPAI 418 FSI+SSDSQAMGR+GEV IRTWQTADKMK QRG L E NDNFR+KRYIAKYTINPAI Sbjct: 356 FSIISSDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAI 415 Query: 419 AHGIAEHIGSLEVGKIADIVLWKPMFFGVKPEVVIKKGFISYAKMGDPNASIPTPQPVFY 478 AHG++ IGSLEVGK AD+VLW P FFGVKP++V+ G I+ A MGDPNASIPTPQPV Y Sbjct: 416 AHGLSHEIGSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHY 475 Query: 479 RPMYGAQGLATAQTAVFFVSQAAEKADIREKFGLHKETIAVKGCR-NVGKKDLVHNDVTP 537 RPM+GA G + ++V FVSQA+ A + + G+ KE +AV+ R +GK ++HN +TP Sbjct: 476 RPMFGAYGRSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTP 535 Query: 538 NITVDAERYEVRVDGELITCEPVDSVPLGQRYFLF 572 +I VD E YEVR DGEL+TCEP +P+ QRYFLF Sbjct: 536 HIEVDPETYEVRADGELLTCEPATVLPMAQRYFLF 570
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 121 bits (304), Expect = 7e-36 Identities = 74/230 (32%), Positives = 117/230 (50%), Gaps = 9/230 (3%) Query: 9 IAALMVSAVISGQVFAEDNTF---DEKAASYAVGTLMGSQMKDLVDSHKEVIKYDNARIL 65 + A ++ +S + A D T D+ SY++G +G K + I + + Sbjct: 6 VTAAIMGLAMSTAMAATDATSLTTDKDKLSYSIGADLGKNFK------NQGIDINPDVLA 59 Query: 66 DGLKDALEGKVDVRKDEKIQKTLESIEAKLVAASKAKAEAIAKQAKEEGDKFRAEFAKGK 125 G++D + G + +E+++ L + L+A A+ A++ K +GD F + Sbjct: 60 KGMQDGMSGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKP 119 Query: 126 DVKTTQSGLMYKIESAGKGDTIKSTDTVKVHYTGKLPNGKVFDSSVERGQPVEFQLDQVI 185 + SGL YKI AG G +DTV V YTG L +G VFDS+ + G+P FQ+ QVI Sbjct: 120 GIVVLPSGLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVI 179 Query: 186 KGWTEGLQLVKKGGKIQLVIAPELGYGEQGAGASIPPNSTLIFDVEVLDV 235 GWTE LQL+ G ++ + +L YG + G I PN TLIF + ++ V Sbjct: 180 PGWTEALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISV 229
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 83.4 bits (206), Expect = 2e-19 Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 25/194 (12%) Query: 13 VNVGTIGHVDHGKTTLT-------AAITTVLAKHYGGAARAFDQIDNAPEEKARGITINT 65 +N+G + HVD GKTTLT AIT + + G + DN E+ RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTT-----RTDNTLLERQRGITIQT 58 Query: 66 SHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQ 125 + +D PGH D++ + + +DGAIL+++A DG QTR R+ Sbjct: 59 GITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRK 118 Query: 126 VGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ--------YDFPGDDTPIVRGSALQ 177 +G+P I F+NK D + L V +++E LS +P + + + + Sbjct: 119 MGIP-TIFFINKIDQNGID--LSTVYQDIKEKLSAEIVIKQKVELYP--NMCVTNFTESE 173 Query: 178 ALNGVAEWEEKILE 191 + V E + +LE Sbjct: 174 QWDTVIEGNDDLLE 187
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 1706 bits (4420), Expect = 0.0 Identities = 1186/1798 (65%), Positives = 1309/1798 (72%), Gaps = 261/1798 (14%) Query: 1 MLNKKFKLNFIALTVAYALTPYTEAALVRNDVDYQIFRDFAENKGKFSVGATNVEVRDNK 60 MLNKKFKLNFIALTVAYALTPYTEAALVR+DVDYQIFRDFAENKGKFSVGATNV V+D Sbjct: 1 MLNKKFKLNFIALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKN 60 Query: 61 NNNLGSALPKDIPMIDFSAVDVDKRIATLVNPQYVVGVKHVGNGVGELHFGNLNGNWNPK 120 N +LG+ALP IPMIDFS VDVDKRIATL+NPQYVVGVKHV NGV ELHFGNLNGN N Sbjct: 61 NKDLGTALPNGIPMIDFSVVDVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMN-- 118 Query: 121 FGNSIQHRDVSWEENRYYTVEKNNFSSELNGKTQNNEKDKQYTSNKKDVPSELYGQALVK 180 GN+ HRDVS EENRY++VEKN + P++L G+ + Sbjct: 119 NGNAKAHRDVSSEENRYFSVEKNEY------------------------PTKLNGKTVTT 154 Query: 181 EQQNQKRREDYYMPRLDKFVTEVAPIEASTTSSDAGTYNDQNKYPAFVRLGSGSQFIYKK 240 E Q QKRREDYYMPRLDKFVTEVAPIEAST SSDAGTYNDQNKYPAFVRLGSGSQFIYKK Sbjct: 155 EDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDAGTYNDQNKYPAFVRLGSGSQFIYKK 214 Query: 241 GSHYELILEEKNEKKEIIHRWDVGGDNLKLVGNAYTYGIAGTPYKVNHTDDGLIGFGDST 300 G +Y LIL +VGG+NLKLVG+AYTYGIAGTPYKVNH ++GLIGFG+S Sbjct: 215 GDNYSLILNN----------HEVGGNNLKLVGDAYTYGIAGTPYKVNHENNGLIGFGNSK 264 Query: 301 EDHNDPKEILSRKPLTNYAVLGDSGSPLFVYDKSKEKWLFLGAYDFWGGYKKKSWQEWNI 360 E+H+DPK ILS+ PLTNYAVLGDSGSPLFVYD+ K KWLFLG+YDFW GY KKSWQEWNI Sbjct: 265 EEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYDFWAGYNKKSWQEWNI 324 Query: 361 YKPQFAENILKKDSAGLLKG-NTQYNWTSKGNTSLISGTSESLSVDLVDNK-NLNHGKNV 418 YK QF +++L KDSAG L G T Y+W+S G TS I+G +SL+VDL D K NHGK+V Sbjct: 325 YKSQFTKDVLNKDSAGSLIGSKTDYSWSSNGKTSTITGGEKSLNVDLADGKDKPNHGKSV 384 Query: 419 TFEGSGNLTLNNNIDQGAGGLFFEGDYEVKGTSENTTWKGAGISVAEGKTVKWKVHNPQF 478 TFEGSG LTLNNNIDQGAGGLFFEGDYEVKGTS+NTTWKGAG+SVAEGKTV WKVHNPQ+ Sbjct: 385 TFEGSGTLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWKGAGVSVAEGKTVTWKVHNPQY 444 Query: 479 DRLAKIGKGKLIVEGRGDNKGSLKVGDGTVVLKQQT-TTGQHAFASVGIVSGRSTVVLND 537 DRLAKIGKG LIVEG GDNKGSLKVGDGTV+LKQQT +GQHAFASVGIVSGRST+VLND Sbjct: 445 DRLAKIGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGSGQHAFASVGIVSGRSTLVLND 504 Query: 538 DNQVDPNSIYFGFRGGRLDANGNNLTFEHIRNIDDGARLVNHNMTNASNITITGAGLITN 597 D QVDPNSIYFGFRGGRLD NGN+LTF+HIRNIDDGARLVNHNMTNASNITITG LIT+ Sbjct: 505 DKQVDPNSIYFGFRGGRLDLNGNSLTFDHIRNIDDGARLVNHNMTNASNITITGESLITD 564 Query: 598 PSQVTIYTPAITADDDNYYYVPSIPRGKDLYFSNTCYKYYALKQGGSPTAEMPCYSSEKS 657 P+ +T Y D+DN Y I G LY + Y YYAL++G S +E+P +S +S Sbjct: 565 PNTITPYN-IDAPDEDNPYAFRRIKDGGQLYLNLENYTYYALRKGASTRSELP-KNSGES 622 Query: 658 DANWEFMGDNQNDAQKKAMVYINNRRMNGFNGYFGEEATKADQNGKLNVTFSGKSDQNRF 717 + NW +MG ++A++ M +INN RMNGFNGYFGEE K NG LNVTF GKS+QNRF Sbjct: 623 NENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGEEEGK--NNGNLNVTFKGKSEQNRF 680 Query: 718 LLTGGTNLNGELKVEKGTLFLSGRPTPHARDIANISSTEKDKHFAENNEVVVEDDWINRT 777 LLTGGTNLNG+L VEKGTLFLSGRPTPHARDIA ISST+KD HFAENNEVVVEDDWINR Sbjct: 681 LLTGGTNLNGDLTVEKGTLFLSGRPTPHARDIAGISSTKKDPHFAENNEVVVEDDWINRN 740 Query: 778 FKATNINVTNNATLYSGRNVESITSNITASNKAKVHIGYKAGDTVCVRSDYTGYVTCHND 837 FKAT +NVT NA+LYSGRNV +ITSNITASNKA+VHIGYK GDTVCVRSDYTGYVTC D Sbjct: 741 FKATTMNVTGNASLYSGRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTD 800 Query: 838 TLSTKALNSFNPTNLRGNVNLTESANFTLGKANLFGTINSTENSQVNLKENSHWYLTGNS 897 LS KALNSFNPTNLRGNVNLTESANF LGKANLFGTI S NSQV L ENSHW+LTGNS Sbjct: 801 KLSDKALNSFNPTNLRGNVNLTESANFVLGKANLFGTIQSRGNSQVRLTENSHWHLTGNS 860 Query: 898 DVHQLDLANGHIHLNNVSDATKETKYHTLNISNLSGNGSFYYWVDFTKNQGDKVVVTKSA 957 DVHQLDLANGHIHLN+ ++ TKY+TL +++LSGNGSFYY D + QGDKVVVTKSA Sbjct: 861 DVHQLDLANGHIHLNSADNSNNVTKYNTLTVNSLSGNGSFYYLTDLSNKQGDKVVVTKSA 920 Query: 958 KGTFTLQVANKTGEPNHNELTLFDASNATERSGLNVSLANGKVDRGAWSYTLKENSGRYY 1017 G FTLQVA+KTGEPNHNELTLFDAS A R LNVSL VD GAW Y L+ +GRY Sbjct: 921 TGNFTLQVADKTGEPNHNELTLFDASKAQ-RDHLNVSLVGNTVDLGAWKYKLRNVNGRYD 979 Query: 1018 LHNPEVERRNQTVDTPSIATANNMQADVPSVSNNHEETARV-EAPIPLPAPPAPATGSAM 1076 L+NPEVE+RNQTVDT +I T NN+QADVPSV +N+EE ARV EAP+P PPAPAT Sbjct: 980 LYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVP---PPAPAT---- 1032 Query: 1077 ANEQPETRPAETVQPTMEDTNTTHPSGSEPQADTTQADDPNSESVPSETIEKVAENSPQE 1136 PSET E VAENS QE Sbjct: 1033 ---------------------------------------------PSETTETVAENSKQE 1047 Query: 1137 SETVAKNEQKATETTAQNDEVAKEAKPTVEANTQTNELAQNGSETEETQEAETARQSEIN 1196 S+TV KNEQ ATETTAQN EVAKEAK V+ANTQTNE+AQ+GSET+ETQ ET + + Sbjct: 1048 SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE 1107 Query: 1197 STEETVVEDDPTISEPKSRPRRSISSSSNNINLAGTEDTAKVETEKTQEAPQVAFQASPK 1256 E+ AKVETEKTQE P+V Q SPK Sbjct: 1108 KEEK-----------------------------------AKVETEKTQEVPKVTSQVSPK 1132 Query: 1257 QEEPEMAKQQEQPKTVQSQAQPETTTQQAEPARENVSTVNNVKEAQPQAKPTTVAAKETT 1316 QE Q ET QAEPAREN TVN KE Sbjct: 1133 QE------------------QSETVQPQAEPARENDPTVN---------------IKEPQ 1159 Query: 1317 ASNSEQKETAQPVANPKTAENKAENPQSTETTDENIHQPEAHTAVASTEVVTPENATTPI 1376 + + +T QP Sbjct: 1160 SQTNTTADTEQPA----------------------------------------------- 1172 Query: 1377 KPVENKTTEAEQPVTETTTVSTENPVVKNPENTTPATTQSTVNSEAVQSETATTEAVVSQ 1436 + ++ EQPVTE+TTV+T N VV+NPENTTPATTQ TVNSE Sbjct: 1173 ---KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSE--------------- 1214 Query: 1437 SKVTSAEETTVASTQETTVDNSGSTPQPRSRRTRRSAQNSYEPVELHTENAENPQSGNDV 1496 S + P+ R RR+ RS ++ EP + + Sbjct: 1215 ---------------------SSNKPKNRHRRSVRSVPHNVEPATTSSNDRST------- 1246 Query: 1497 ATQLVLRDLTSTNTNAVISDAMAKAQFVALNVGKAVSQHISQLEMNNEGQYNVWVSNTSM 1556 + L DLTSTNTNAV+SDA AKAQFVALNVGKAVSQHISQLEMNNEGQYNVWVSNTSM Sbjct: 1247 ---VALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYNVWVSNTSM 1303 Query: 1557 KENYSSSQYRHFSSKSAQTQLGWDQTISSNVQLGGVFTYVRNSNNFDKASSKNTLAQANL 1616 +NYSSSQYR FSSKS QTQLGWDQTIS+NVQLGGVFTYVRNSNNFDKA+SKNTLAQ N Sbjct: 1304 NKNYSSSQYRRFSSKSTQTQLGWDQTISNNVQLGGVFTYVRNSNNFDKATSKNTLAQVNF 1363 Query: 1617 YSKYYMDNHWYLAVDLGYGNFQSNLQTNHNAKFARHTAQFGLTAGKAFNLGNFAVKPTVG 1676 YSKYY DNHWYL +DLGYG FQS LQTNHNAKFARHTAQFGLTAGKAFNLGNF + P VG Sbjct: 1364 YSKYYADNHWYLGIDLGYGKFQSKLQTNHNAKFARHTAQFGLTAGKAFNLGNFGITPIVG 1423 Query: 1677 VRYSYLSNANFALAKDRIKVNPISVKTAFAQVDLSYTYHLGEFSITPILSARYDANQGSG 1736 VRYSYLSNA+FAL + RIKVNPISVKTAFAQVDLSYTYHLGEFS+TPILSARYDANQGSG Sbjct: 1424 VRYSYLSNADFALDQARIKVNPISVKTAFAQVDLSYTYHLGEFSVTPILSARYDANQGSG 1483 Query: 1737 KINVDRYDFAYNVENQQQYNAGLKLKYHNVKLSLIGGLTKAKQAEKQKTAEVKLSFSF 1794 KINV+ YDFAYNVENQQQYNAGLKLKYHNVKLSLIGGLTKAKQAEKQKTAE+KLSFSF Sbjct: 1484 KINVNGYDFAYNVENQQQYNAGLKLKYHNVKLSLIGGLTKAKQAEKQKTAELKLSFSF 1541
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 779 bits (2013), Expect = 0.0 Identities = 304/551 (55%), Positives = 397/551 (72%), Gaps = 16/551 (2%) Query: 1 MDSRRSLLVLALIFISFLVYQQWQLDKNPPVQTEQTTSITATSDVPASSPSNSQAIADSQ 60 MDS+R+LLV+AL+F+SF+++Q W+ DKNP Q +QTT T T+ A S ++ A Q Sbjct: 1 MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTA---AGSAADQGVPASGQ 57 Query: 61 TRGRIITLENDVFRLKIDTLGGDVISSELLKYDAELDSKTPFELLKDTKEHIYIAQSGLI 120 G++I+++ DV L I+T GGDV + L Y EL+S PF+LL+ + + IY AQSGL Sbjct: 58 --GKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLT 115 Query: 121 GKNGIDTRSG--RAQYQIEGDNFKLAEGQESLSVPLLF-EKDGVTYQKIFVLKRGSYDLG 177 G++G D + R Y +E D + LAEGQ L VP+ + + G T+ K FVLKRG Y + Sbjct: 116 GRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVN 175 Query: 178 VDYKIDNQSGQAIEVEPYGQLKHSII------ESSGNVAMPTYTGGAYSSSETNYKKYSF 231 V+Y + N + +E+ +GQLK SI S N A+ T+ G AYS+ + Y+KY F Sbjct: 176 VNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKF 235 Query: 232 ADMQDN-NLSIDTKAGWVAVLQHYFVSAWIPNQDVNNQLYTITDSKNNVASIGYRGPVVT 290 + DN NL+I +K GWVA+LQ YF +AWIP+ D N YT + N +A+IGY+ V Sbjct: 236 DTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYT-ANLGNGIAAIGYKSQPVL 294 Query: 291 IPAGSQETITSSLWTGPKLQNQMATVANNLDLTVDYGWAWFIAKPLFWLLTFIQGIVSNW 350 + G + S+LW GP++Q++MA VA +LDLTVDYGW WFI++PLF LL +I V NW Sbjct: 295 VQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNW 354 Query: 351 GLAIICVTIVVKAILYPLTKAQYTSMAKMRILQPKMQEMRERFGDDRQRMSQEMMKLYKE 410 G +II +T +V+ I+YPLTKAQYTSMAKMR+LQPK+Q MRER GDD+QR+SQEMM LYK Sbjct: 355 GFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKA 414 Query: 411 EKVNPLGGCLPILLQMPIFIALYWTFLEAVELRHAPFFGWIQDLSAQDPYYILPILMGIS 470 EKVNPLGGC P+L+QMPIF+ALY+ + +VELR APF WI DLSAQDPYYILPILMG++ Sbjct: 415 EKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVT 474 Query: 471 MFLLQKMSPTPVTDPTQQKVMNFMPLVFMFFFLWFPSGLVLYWLVSNLITIAQQQLIYRG 530 MF +QKMSPT VTDP QQK+M FMP++F FFLWFPSGLVLY++VSNL+TI QQQLIYRG Sbjct: 475 MFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRG 534 Query: 531 LEKKGLHSRKK 541 LEK+GLHSR+K Sbjct: 535 LEKRGLHSREK 545
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 28.4 bits (63), Expect = 0.034 Identities = 9/51 (17%), Positives = 23/51 (45%), Gaps = 4/51 (7%) Query: 43 GLFWLFISQISSAIDWVMNFIPDWLSFLSVILLTLSILTILLLFYFTFTTF 93 G W + + W+ +F+ +W S+I++T + +++ T + Sbjct: 331 GWLWFISQPLFKLLKWIHSFVGNW--GFSIIIIT--FIVRGIMYPLTKAQY 377
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 97.9 bits (244), Expect = 1e-25 Identities = 78/348 (22%), Positives = 130/348 (37%), Gaps = 68/348 (19%) Query: 2 IIVTGGAGFIGSNIVKALNDLGRKDILVVDNLKD--------------GTKFANLVDLDI 47 +VTG AGFIG ++ K L + G ++ +DNL D +D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 48 ADYCDKEDFIASIIAGDEFGDIDAVFHEGACSATTEWDGKYIMHNNYEYSK-------EL 100 AD + + + A F + VF A +Y + N + Y+ + Sbjct: 62 ADR----EGMTDLFASGHF---ERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNI 109 Query: 101 LHYCLDREIP-FFYASSAATYGDTKV--FREEREFEGPLNVYGYSKFLFDQYVRNILPEA 157 L C +I YASS++ YG + F + + P+++Y +K + Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 158 KSPVCGFRYFNVYGPRENHKGSMASVAFHLNNQILKGENPKLFAGSEGFRRDFVYVGDVA 217 P G R+F VYGP + MA F +L+G++ ++ +RDF Y+ D+A Sbjct: 170 GLPATGLRFFTVYGPWG--RPDMA--LFKFTKAMLEGKSIDVY-NYGKMKRDFTYIDDIA 224 Query: 218 AVNI------------WCWQNGISG-------IYNLGTGNAESFRAVADAVVKFHG-KGE 257 I W + G +YN+G + A+ G + + Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 258 IETIPFPEHLKSRYQEYTQADLTKLRS-TGYDKPFKTVAEGVTEYMAW 304 +P T AD L G+ P TV +GV ++ W Sbjct: 285 KNMLPLQPG----DVLETSADTKALYEVIGF-TPETTVKDGVKNFVNW 327
>SECA#SecA protein signature. Length = 901 Score = 27.9 bits (62), Expect = 0.025 Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 11/37 (29%) Query: 75 TSPA-INSLANEGYQVVSVALRSGNEADVNDYLSKHD 110 T PA +N+L +G VV+V NDYL++ D Sbjct: 113 TLPAYLNALTGKGVHVVTV----------NDYLAQRD 139
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.1 bits (86), Expect = 2e-04 Identities = 39/178 (21%), Positives = 58/178 (32%), Gaps = 53/178 (29%) Query: 194 DLTDIIGQ----QHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTGILPEMTDLEAIE 249 D ++G+ Q R L L+ G GTGK ++A A+ Sbjct: 135 DGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA-------------RALH 181 Query: 250 TASVTSLVQNELNFHNWKQRPFRAPHHSASMP------ALVG-------GGTIPKPGEIS 296 + PF A + A++P L G G G Sbjct: 182 DYG------------KRRNGPFVAI-NMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFE 228 Query: 297 LATNGALFLDEL----PEFERKVLDALRQPLESGEIIISRANAKIQFPARFQLVAAMN 350 A G LFLDE+ + + ++L L+ GE I+ R +VAA N Sbjct: 229 QAEGGTLFLDEIGDMPMDAQTRLLRV----LQQGEYTTVGGRTPIRSDVR--IVAATN 280
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.0 bits (67), Expect = 0.003 Identities = 15/78 (19%), Positives = 29/78 (37%), Gaps = 3/78 (3%) Query: 20 ELTLEQAENALEKLQTAIEEKRANEAELIKAETERKERL-AKYKELMEKEGITPEELHEI 78 E T + E A E + NE +ET+ + K +EKE E + Sbjct: 1060 ETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKT 1119 Query: 79 FGTKTVSIRAKRAPRPAK 96 + + ++ +P+ + Sbjct: 1120 --QEVPKVTSQVSPKQEQ 1135
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 473 bits (1218), Expect = e-170 Identities = 148/358 (41%), Positives = 217/358 (60%), Gaps = 6/358 (1%) Query: 4 KPATAKISSHALKQNLEIIKQKAPNSKIIAVVKANAYGHGVVFVASTLEQNVDCFGVARL 63 +P A + ALKQNL I++Q A ++++ +VVKANAYGHG+ + S + D F + L Sbjct: 3 RPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGA-TDGFALLNL 61 Query: 64 EEALALRSNGITKPILLLEGFFNEQDLPILAVNNIETVVHNHEQLEALKRSNLPSPIKVW 123 EEA+ LR G PIL+LEGFF+ QDL I + + T VH++ QL+AL+ + L +P+ ++ Sbjct: 62 EEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIY 121 Query: 124 LKIDTGMHRLGVALDEVDYFYQELKKLPQIQPHLGFVSHFSRADELESDYTQLQINRFLS 183 LK+++GM+RLG D V +Q+L+ + + + +SHF+ A+ D + R Sbjct: 122 LKVNSGMNRLGFQPDRVLTVWQQLRAMANVG-EMTLMSHFAEAEH--PDGISGAMARIEQ 178 Query: 184 ATKDKQGERTIAASGGILFWPKSHLECIRPGIIMYGISPTDTIGK--EFGLTPVMNLTSS 241 A + + R+++ S L+ P++H + +RPGII+YG SP+ GL PVM L+S Sbjct: 179 AAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSE 238 Query: 242 LIAVRHHKQGDPVGYGGIWTSPRDTKIGVVAMGYGDGYPRDVPEGTPVYLNGRLVPIVGR 301 +I V+ K G+ VGYGG +T+ + +IG+VA GY DGYPR P GTPV ++G VG Sbjct: 239 IIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGT 298 Query: 302 VSMDMLTVDLGADSQDLVGDEVILWGKELPIETVAKFTGILSYELITKLTPRVITEYV 359 VSMDML VDL Q +G V LWGKE+ I+ VA G + YEL+ L RV V Sbjct: 299 VSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRVPVVTV 356
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 30.3 bits (68), Expect = 0.007 Identities = 19/85 (22%), Positives = 30/85 (35%), Gaps = 17/85 (20%) Query: 166 WFEWEKDNRKEIPKLHPT-------------QKPIAVLKRLIEIFTDEGDVVIDPVAG-- 210 W WE+D + T P + +LI + TD D+ I+ G Sbjct: 20 WQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDV 79 Query: 211 -SASTLRAARELNRPSYGFEIKKDS 234 A +ELN F++ + S Sbjct: 80 EQALLPAYPKELNSTQ-PFQLLETS 103
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 28.3 bits (63), Expect = 0.036 Identities = 11/71 (15%), Positives = 27/71 (38%), Gaps = 1/71 (1%) Query: 117 LPPLVNELNPEPSIEPSDNHHIKKTTQKSESEMLLEQF-GITGQLAKDFIAHRKAKKGVI 175 PP +LNP + K+ + + + + F G++ L+ + K + Sbjct: 164 YPPKSPKLNPFDFSYDMIENFTKENSLQLNDNIFSKIFTGVSKTLSSEICFRLKNNSIDL 223 Query: 176 NQTQLNRLQKQ 186 + + L + + Sbjct: 224 SLSNLKEIVEV 234
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 25.5 bits (55), Expect = 0.023 Identities = 13/45 (28%), Positives = 24/45 (53%) Query: 29 RLGNAKDAIKSAQMAYTNPNFVRQIKKDPDKLIYQGIQALIAKYG 73 +LGNA + + PN ++Q+ ++ KL QG+Q + + G Sbjct: 436 KLGNALSKMMGETIKKLVPNVLKQLAQNGSKLFTQGMQRITSGLG 480
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 26.8 bits (59), Expect = 0.046 Identities = 13/49 (26%), Positives = 22/49 (44%), Gaps = 2/49 (4%) Query: 27 DTPEQQFQQGLTAYEQSNYQTAFKL--WLPLAEQGDAQAQGGLGMMYER 73 DT EQ + Y+ Y+ A K+ L + + D++ GLG + Sbjct: 34 DTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQA 82
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 2e-22 Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 4/130 (3%) Query: 1 MTR-KILIVEDECAIREMIALFLSQKYYDVIEASDFKTAINKI-KENPKLILLDWMLPGR 58 MT IL+ +D+ AIR ++ LS+ YDV S+ T I + L++ D ++P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 59 SGIQFIQYIKKQESYAAIPIIMLTAKSTEEDCIACLNAGADDYITKPFSPQILLARIEAV 118 + + IKK +P+++++A++T I GA DY+ KPF L+ I Sbjct: 61 NAFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 119 WRRIYEQQSQ 128 + S+ Sbjct: 119 LAEPKRRPSK 128
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 41.6 bits (97), Expect = 2e-05 Identities = 26/267 (9%), Positives = 78/267 (29%), Gaps = 18/267 (6%) Query: 881 EINRERNEIDRELNQFNNGEQQLRIQLDNAKEKLQLLNKLIPQLNVLTDEDLIDRIEECR 940 +++ + ++ + +L + L I +L + + Sbjct: 75 DLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKAD----LEKALE 130 Query: 941 EQLDIAEQDEYFIRQYGVTLSQLEPIANSLQSDPENYDGLKNELTQAIERQKQVQQRVFA 1000 ++ + D I+ + L L+ E + I+ + + + A Sbjct: 131 GAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEA 190 Query: 1001 LADVVQRKHHFGYEDAGQAKTSELNEKLRQRLEQMQAQRDMQREQVRQKQSQFAEYNRVL 1060 +++ + +++ ++A++ + + Sbjct: 191 RQAELEKALE---------GAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFS 241 Query: 1061 IQLQSSYDSKYQLLNELISEISDLGVRADDGAEERARIRRDELHQQLSTSRQRRSYVEKQ 1120 + + L + ++L + A E A ++ T ++ +E + Sbjct: 242 TADSAKIKTLEAEKAALEARQAEL-----EKALEGAMNFSTADSAKIKTLEAEKAALEAE 296 Query: 1121 LTLIESEADNLNRLIRKTERDYKTQRE 1147 +E ++ LN + RD RE Sbjct: 297 KADLEHQSQVLNANRQSLRRDLDASRE 323 Score = 34.3 bits (78), Expect = 0.005 Identities = 50/358 (13%), Positives = 111/358 (31%), Gaps = 29/358 (8%) Query: 414 ANDALEESQAQFEQTEIEIDAVRAQLADYQQALDAQQTRALQYQQAITALEKAKTLCGLA 473 + E S ++ V+ + ++ + + + AL+ Sbjct: 34 VVNTNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKD-------- 85 Query: 474 DLSVKNVEDYHAEFEAHAESLTETVLELEHKMSISEAAKSQFDKAYQLVCKIAGEIPRSS 533 + + + + +++ E K+ EA K+ +KA + + Sbjct: 86 --HNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKI 143 Query: 534 AWESAKELLREYPSQKLQAQQTPQLRTKLHELEQRYAQQQSAVKLLNDFNQRANLSLQTA 593 E + + + ++ L +L+ A Sbjct: 144 K-TLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA 202 Query: 594 EELEDYHAEQEALIEDISARLSEQVENRSTLRQKRENLTALYDENARKAPAWLTAQAALE 653 A I+ + A + ++ L + E ++ K T +A Sbjct: 203 MNFST---ADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIK---TLEAEKA 256 Query: 654 RLEQQSGETFEHSQDVMNFMQSQLVKERELTMQRDQLEQKRLQLDE--QISRLSQPDGSE 711 LE + E + + MNF + K + L ++ LE ++ L+ Q+ ++ Sbjct: 257 ALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRR 316 Query: 712 DPRLNMLAERFGGVLLSELYDDVTIEDAPYFSALYGPARHAIVVRDLNAVREQLAQLE 769 D + A++ +L + I +A + + RDL+A RE QLE Sbjct: 317 DLDASREAKKQLEAEHQKLEEQNKISEA----SRQS------LRRDLDASREAKKQLE 364 Score = 32.0 bits (72), Expect = 0.019 Identities = 36/269 (13%), Positives = 76/269 (28%), Gaps = 22/269 (8%) Query: 1020 KTSELNEKLRQRLEQMQAQRDMQREQVRQKQSQFAEYNRVLIQLQSSYDSKYQLLNELIS 1079 K E +K ++ + + + E L + + L+E S Sbjct: 54 KVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKAS 113 Query: 1080 EISDLGVRADDG-----AEERARIRRDELHQQLSTSRQRRSYVEKQLTLIESEADNLNRL 1134 +I +L R D + L + + + L A N + Sbjct: 114 KIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTA 173 Query: 1135 IRKTERDYKTQRELVVAAKVSWCVVLRLSRNSDMEKRLNRRELAYLSADELRSMSDKALG 1194 + + ++ + A R +++EK L + + Sbjct: 174 DSAKIKTLEAEKAALEA------------RQAELEKALEGAMNFSTADSAKIKTLEAEKA 221 Query: 1195 ALRTAVADNEYLRDSLR-VSEDSRKPENKVRFFIAVYQH----LRERIRQDIIKTDDPID 1249 AL AD E + S + A + L + + + + Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 1250 AIEQMEIELSRLTAELTGREKKLAISSES 1278 I+ +E E + L AE E + + + + Sbjct: 282 KIKTLEAEKAALEAEKADLEHQSQVLNAN 310
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 69.9 bits (171), Expect = 2e-14 Identities = 59/278 (21%), Positives = 96/278 (34%), Gaps = 77/278 (27%) Query: 350 IMGHVDHGKTSLLDYIRKAKVAAGEAG------------------GITQHIGAYHVEMDD 391 ++ HVD GKT+L + + A E G GIT G + ++ Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 392 GKMITFLDTPGHAAFTSMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAAGAPLVVA 451 K + +DTPGH F + R D +L+++A DGV QT + G P + Sbjct: 68 TK-VNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFF 126 Query: 452 VNKIDKPEANP-----------------------------------DRVEQELLQHDVIS 476 +NKID+ + ++ + + +D + Sbjct: 127 INKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLL 186 Query: 477 EKFGGDVQ------------------FVPV---SAKKGTGVDDLLDAILLQSEVLELTAV 515 EK+ PV SAK G+D+L++ I ++ T Sbjct: 187 EKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHR 244 Query: 516 KDGMASGVVIESYLDKGRGPVATILVQSGTLRKGDIVL 553 G V + + R +A I + SG L D V Sbjct: 245 GQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVR 282
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 29.6 bits (66), Expect = 0.012 Identities = 27/201 (13%), Positives = 59/201 (29%), Gaps = 14/201 (6%) Query: 5 ELTVLLNAIDKISAPVRSASKSVHELSAKLKESKSIHRQLNQQNKQHQAAMKQYASAINP 64 L+ + I ++ A K++ + + L + A A+ Sbjct: 107 SLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEG 166 Query: 65 LKSKLDSL---NQELEQAKQKAASYAQYMKN-----------AQHPTAGFQKEVEKAKSA 110 + + + LE K + ++ + E + Sbjct: 167 AMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAAR 226 Query: 111 VKKLKQEQIDAANKLQQARQELAKSGISAEKLAQKQRELQKNTKSATDQIKNQEAALKKL 170 L++ A N ++ L +Q EL+K + A + A +K L Sbjct: 227 KADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTL 286 Query: 171 NAKQAAYNQYRGQVEKLKDIS 191 A++AA + +E + Sbjct: 287 EAEKAALEAEKADLEHQSQVL 307
>SECA#SecA protein signature. Length = 901 Score = 26.0 bits (57), Expect = 0.025 Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 52 DLSDEDLKKLAAELKKRCGCGGSVKNGIIEF 82 LSDE+LK AE + R G ++N I E Sbjct: 37 KLSDEELKGKTAEFRARLEKGEVLENLIPEA 67
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 107 bits (270), Expect = 2e-34 Identities = 34/89 (38%), Positives = 52/89 (58%), Gaps = 1/89 (1%) Query: 2 TKSELMEKLSAKQPTLSAKEIENMVKDILEFISQSLENGDRVEVRGFGSFSLHHRQPRLG 61 K +L+ K+ A+ L+ K+ V + +S L G++V++ GFG+F + R R G Sbjct: 3 NKQDLIAKV-AEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 62 RNPKTGDSVNLSAKSVPYFKAGKELKARV 90 RNP+TG+ + + A VP FKAGK LK V Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.2 bits (68), Expect = 0.028 Identities = 25/162 (15%), Positives = 51/162 (31%), Gaps = 22/162 (13%) Query: 318 PSKVVSLGDTVEVMVLEIDEERRRISLG-LKQCKANPWTQFADTHNKGDKVTGKIKSITD 376 + T ++ ++ + +I+ G L A P Q N + K+ + Sbjct: 190 ADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQL----NASIIAQTRFKNPEE 245 Query: 377 FGIFIGLEGGIDGLVHLSDISWSISGEEAVRQYKKGDEVSAVVLAV------------DA 424 FG +V L D++ G E + + A L + A Sbjct: 246 FGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKA 305 Query: 425 VKERISLGIKQLEED-----PFNNFVAINKKGAVVSATVVEA 461 +K +++ + P++ + V T+ EA Sbjct: 306 IKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEA 347
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 30.7 bits (69), Expect = 0.008 Identities = 18/74 (24%), Positives = 28/74 (37%), Gaps = 6/74 (8%) Query: 153 KIKKHYTVYPNYKNIVSNIEPISLWDNQIDCEIDG--EVSFFIGQPLLNTKEENISLIKK 210 I+K + + P + PIS+ D +I + QP LN ++ + I Sbjct: 127 PIRKPFKLTPPQPTMS----PISIADRDFGIDIPNIPQAQRQAAQPPLNDQKRAAARIAW 182 Query: 211 LKEQFSFDYYFPHP 224 LK DY P Sbjct: 183 LKNCAGIDYMVKDP 196
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 29.8 bits (67), Expect = 0.016 Identities = 11/57 (19%), Positives = 22/57 (38%), Gaps = 8/57 (14%) Query: 4 FALIVGIVALAIFSFLYIQLYRV--------QSAINEQLAQQNIAVQSINLSLFSPA 52 + +V + +L I SFL + ++R+ Q+ + V +L P Sbjct: 15 YFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEPPYNLMVPR 71
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 54.4 bits (131), Expect = 3e-10 Identities = 46/277 (16%), Positives = 96/277 (34%), Gaps = 12/277 (4%) Query: 46 QTADTGLMMTVYAWTVLIMSLPAMLATGNMERKSLLIKLFIIFIVGHILLVIAWNFWILL 105 TA G+++ +YA + + R+ +L+ V + ++ A W+L Sbjct: 41 VTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLY 100 Query: 106 LARMCIALAHSVFWSITASLVMRISPKHKKTQALGMLAIGTALATILGLPIGRIVGQLVG 165 + R+ + + ++ + + I+ ++ + G ++ + G +G ++G Sbjct: 101 IGRIVAGITGATG-AVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FS 158 Query: 166 WRVTFGIIAVLALSIMFLIIRLLP--------NLPSKNAGSIASLPLLAKRPLLLWLYVT 217 F A L LLP L + +AS ++ L Sbjct: 159 PHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAV 218 Query: 218 TAIVISAHFTAYTYIEPFMIDVGHLDPNFATAVLLVFGFSG-IAASLLFNRLY-RFAPTK 275 I+ F D H D L FG +A +++ + R + Sbjct: 219 FFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERR 278 Query: 276 FIVVSMSLLMFSLLLLLFSTEAIIAMFSLVFIWGIGI 312 +++ M +LL F+T +A +V + GI Sbjct: 279 ALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGI 315
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 32.0 bits (72), Expect = 0.006 Identities = 15/49 (30%), Positives = 24/49 (48%) Query: 166 EKMENADENDRTSEEEQDEWEQEFDFDSEEDTALIDDALDEELEEEQDK 214 K NA+ + +Q E+EFD+ +E AL++ EL E + K Sbjct: 388 SKKNNAEMKSKQMSTDQMTSEKEFDYYTETLKALLEKEDSAELNENEKK 436
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 44.8 bits (106), Expect = 3e-07 Identities = 60/346 (17%), Positives = 121/346 (34%), Gaps = 38/346 (10%) Query: 1 MKKTLAALIVGAFAASAANAAVVYNNEGTNVELGGRLSIIAEQSNSTIKDQKQQHGALRN 60 MKK+L AL + A +A +Y VE ++ Q+ S + + Sbjct: 1 MKKSLIALTLAALPVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTG-----IVD 55 Query: 61 QSSRFHIKATHNFGDGFYAQGYLETRLVSAQSGTESDNFGHIITKYAYVTLGNKALGEVK 120 S+ K + G+G A +E + A GT+S + +++ L G+++ Sbjct: 56 LGSKIGFKGQEDLGNGLKAIWQVEQKASIA--GTDSGWG----NRQSFIGLK-GGFGKLR 108 Query: 121 LGRAKTIADGITS--AEDKEYGVLNNSKYIPTNGNTVGYTFKGID--GLVLGANYLLAQE 176 +GR ++ D + L +K + + + GL Y L Sbjct: 109 VGRLNSVLKDTGDINPWDSKSDYLGVNKIAEPEARLISVRYDSPEFAGLSGSVQYALNDN 168 Query: 177 RHK---------YTTAAGTRAVTVAG---------EVYPQKISNGVQVGAKYDANNIIAG 218 + + G V G E + ++ + YD + + A Sbjct: 169 AGRHNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYAS 228 Query: 219 IAYGRTNYREDIVDPDLGKKQQVNGALSTLGYRFSDLGLLVSLDSGYAKTKNYKDKHEKS 278 + + +V+ + Q +TL YRF ++ VS G+ + + + + Sbjct: 229 V-AVQQ-QDAKLVEENYSHNSQ-TEVAATLAYRFGNVTPRVSYAHGFKGSFDATNYNNDY 285 Query: 279 YFVSPGFQYELMEDTNVYGNFKYERDSVDQGKKTREQAVLFGVDHK 324 V G +Y+ + T+ + + ++ + K A G+ HK Sbjct: 286 DQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFVST-AGGVGLRHK 330
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 33.9 bits (78), Expect = 0.001 Identities = 12/29 (41%), Positives = 19/29 (65%) Query: 339 PARAIGIDDRLGSVEKGKIANLAVFTPNY 367 PA A G+ +GS+E GK A+L ++ P + Sbjct: 413 PAIAHGLSHEIGSLEVGKRADLVLWNPAF 441
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 36.3 bits (84), Expect = 2e-04 Identities = 33/192 (17%), Positives = 67/192 (34%), Gaps = 53/192 (27%) Query: 51 LEESAVENEEKLPTPHEIRAHLDDYVIGQDYAKKVLSVAVYNHYKRLRTNYESNDVELGK 110 + A+ ++ P+ E + ++G+ A +Y R + Sbjct: 114 IIGRALAEPKRRPSKLEDDSQDGMPLVGRSAA----MQEIYRVLAR---------LMQTD 160 Query: 111 SNILLIGPTGSGKTLLAQTL---ARRLNVPFAMADATTLTEAGYVGEDVENVLQKLLQNC 167 +++ G +G+GK L+A+ L +R N PF + + ++++ L Sbjct: 161 LTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIP---------RDLIESELFGH 211 Query: 168 EYDT------------EKAEKGIIYIDEIDKISRKSEGASITRDVSGEGVQQALLKLIEG 215 E E+AE G +++DEI + Q LL++++ Sbjct: 212 EKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMP--------------MDAQTRLLRVLQQ 257 Query: 216 TIASIPPQGGRK 227 GGR Sbjct: 258 G--EYTTVGGRT 267
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 140 bits (353), Expect = 4e-46 Identities = 50/121 (41%), Positives = 73/121 (60%), Gaps = 1/121 (0%) Query: 18 EGKSKGLNTFLWVLVVIFFAAAAIGNIYFQQIYSLPIRVIGMAIALVIAFILAAITNQGT 77 +G +GL WV+VV A +GN ++ I LP+R + + I + A +A +T +G Sbjct: 8 QGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIM-LPLRALAVVILIAAAGGVALLTTKGK 66 Query: 78 KARAFFNDSRTEARKVVWPTRAEARQTTLIVIGVTMIASLFFWAVDSIIVTVINFLTDLR 137 AF ++RTE RKV+WPTR E TTLIV VT + SL W +D I+V +++F+T LR Sbjct: 67 ATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVSFITGLR 126 Query: 138 F 138 F Sbjct: 127 F 127
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 318 bits (817), Expect = e-113 Identities = 106/253 (41%), Positives = 156/253 (61%), Gaps = 11/253 (4%) Query: 4 KVILTAL-LSAIALTGCANHNATKQASERNDSLEDFNRTMWKFNYNVIDRYVLEPAAKGW 62 K+ L+AL L L GCA+ +Q R+D LE FNRTM+ FN+NV+D Y++ P A W Sbjct: 2 KLRLSALALGTTLLVGCASSGTDQQ--GRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAW 59 Query: 63 NNYVPKPISSGLAGIANNLDEPVSFINRLIEGEPKKAFVHFNRFWINTVFGLGGFIDFAS 122 +YVP+P +GL+ NL+EP +N ++G+P + VHF RF++NT+ G+GGFID A Sbjct: 60 RDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAG 119 Query: 123 -ASKELRIDNQRGFGETLGSYGVDAGTYIVLPIYNATTPRQLTGAVVDAAYMYPFWQWVG 181 A+ +L+ FG TLG YGV G Y+ LP Y + T R G + DA +YP W+ Sbjct: 120 MANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADA--LYPVLSWLT 177 Query: 182 GPWALVKYGVQAVDARAKNLNNAELLRQAQDPYITFREAYYQNLQFKVNDGKLVESK--- 238 P ++ K+ ++ ++ RA+ L++ LLRQ+ DPYI REAY+Q F N G+L + Sbjct: 178 WPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPN 237 Query: 239 -ESLPDDILKEID 250 +++ DD LK+ID Sbjct: 238 AQAIQDD-LKDID 249
>PF01206#SirA family protein Length = 76 Score = 90.2 bits (224), Expect = 5e-28 Identities = 24/71 (33%), Positives = 42/71 (59%) Query: 8 QTLNTLGLRCPEPVMLVRKNIRHLNDGEILLIIADDPATTRDIPSFCQFMDHTLLQSEVE 67 Q+L+ GL CP P++ +K + +N GE+L ++A DP + +D SF + H LL+ + E Sbjct: 6 QSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKEE 65 Query: 68 KPPFKYWVKRG 78 + + +KR Sbjct: 66 DGTYHFRLKRA 76
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.1 bits (234), Expect = 1e-24 Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 2/118 (1%) Query: 2 SKLLLVDDDIELTELLSTLLELEGFDVETANNGLEALQKL-NESYKLVLLDVMMPKLNGI 60 + +L+ DDD + +L+ L G+DV +N + + LV+ DV+MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 61 ETLKEIRKV-SNVPVMMLTARGEDIDRVLGLELGADDCLPKPFNDRELIARIKAILRR 117 + L I+K ++PV++++A+ + + E GA D LPKPF+ ELI I L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 28.1 bits (63), Expect = 0.014 Identities = 9/34 (26%), Positives = 15/34 (44%) Query: 216 DQGELNKEQTQAVKKQVFEYCKGQLSNGNNIELR 249 + EL K+ + A VF L+ G ++L Sbjct: 13 EATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLI 46
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 26.3 bits (58), Expect = 0.011 Identities = 8/30 (26%), Positives = 17/30 (56%) Query: 22 VLEKHKAPVDLSLIALGNMASNLLTTSVPQ 51 +L + P+ + +A + ++LLT S P+ Sbjct: 418 ILRNIQPPLVVVFVASNFINAHLLTDSFPR 447
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 29.0 bits (65), Expect = 0.027 Identities = 7/50 (14%), Positives = 18/50 (36%) Query: 39 KIGIYHSSNLQQKWDLVDEVKRTSSVDDYYARFCQSIELMISQGVTAFGT 88 K G+ S ++ V+ + + D ++ + + G+ A Sbjct: 28 KAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQEDLGNGLKAIWQ 77
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.5 bits (141), Expect = 5e-13 Identities = 19/76 (25%), Positives = 34/76 (44%) Query: 1 MRQAKTDLAEQIFLATDRLMAKEGLDRLSMHKIAKEANVAAGTIYLYFKNKDELLEQFAH 60 +Q + + I RL +++G+ S+ +IAK A V G IY +FK+K +L + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 RVFSMFMATLEKDFDE 76 S + + Sbjct: 65 LSESNIGELELEYQAK 80
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 52.5 bits (126), Expect = 1e-09 Identities = 16/55 (29%), Positives = 30/55 (54%) Query: 90 GTISQVLVQNGQNVKKGEVLVELDSSVERANLQAAQAQLSALRQTYQRYVGLLNS 144 + +++V+ G++V+KG+VL++L + A+ Q+ L R RY L S Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRS 159 Score = 41.0 bits (96), Expect = 6e-06 Identities = 43/223 (19%), Positives = 79/223 (35%), Gaps = 36/223 (16%) Query: 113 DSSVERANLQAAQAQLSALRQTYQRYVGLLNSNAVS--RQEMDNAKAAYDAQLANIESLK 170 + V ++ L+ ++++ + ++ YQ L + + RQ DN +LA + Sbjct: 267 ELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNI-GLLTLELA---KNE 322 Query: 171 AVIERRKIVAPFDGKAGIVKIN-VGQYVNVGT---EIVRVEDTSSMKVDFALSQNDLDKL 226 + I AP K +K++ G V IV +DT ++V + D+ + Sbjct: 323 ERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT--LEVTALVQNKDIGFI 380 Query: 227 HIGQRVTATTDARLGETFSARITAIEPAINSSTGLVDVQATFNPEDGHKLLSGMFSRLRI 286 ++GQ +A F + G V ED G+ + I Sbjct: 381 NVGQNAIIKVEA-----FPYTRY---GYL---VGKVKNINLDAIEDQR---LGLVFNVII 426 Query: 287 ALPTETNQVVVPQVAISYNMYGE----------IAYLLEPLSE 319 ++ + +S M I+YLL PL E Sbjct: 427 SIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEE 469
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 902 bits (2333), Expect = 0.0 Identities = 326/1044 (31%), Positives = 537/1044 (51%), Gaps = 47/1044 (4%) Query: 11 DIFIRRPVLAVSISLLMIILGLQAISKLAVREYPKMTTTVITVSTAYPGADANLIQAFVT 70 + FIRRP+ A +++++++ G AI +L V +YP + ++VS YPGADA +Q VT Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 71 SKLEESIAQADNIDYMSSTSAPS-SSTITIKMKLNTDPAGALADVLAKVNAVKSALPNGI 129 +E+++ DN+ YMSSTS + S TIT+ + TDP A V K+ LP + Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 130 EDPSVSSS-SGGSGIMYISFRSKKLDSSQ--VTDYINRVVKPQFFTIEGVAEVQVFGAAE 186 + +S S S +M F S ++Q ++DY+ VK + GV +VQ+FGA + Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA-Q 181 Query: 187 YALRIWLDPQKMAAQNLSVPTVMSALSANNVQTAAGNDN------GYYVSYRNKVETTTK 240 YA+RIWLD + L+ V++ L N Q AAG G ++ +T K Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 241 SVEQLSNLIISSNGD-DLVRLRDIATVELNKENDNSRATANGAESVVLAINPTSTANPLT 299 + E+ + + N D +VRL+D+A VEL EN N A NG + L I + AN L Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 300 VAEKIRPLYESIKTQLPDSMESDILYDRTIAINSSIHEVIKTIGEATLIVLVVILMFIGS 359 A+ I+ ++ P M+ YD T + SIHEV+KT+ EA ++V +V+ +F+ + Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 360 FRAILIPILAIPISLIGVLMLLQSFNFSINLMTLLALILAIGLVVDDAIVVLENIDRHIK 419 RA LIP +A+P+ L+G +L +F +SIN +T+ ++LAIGL+VDDAIVV+EN++R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 420 AGETPFRAAII-GTREIAVPVISMTIALIAVYSPMALMGGITGTLFKEFALTLAGAVFIS 478 + P + A +I ++ + + L AV+ PMA GG TG ++++F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 479 GVVALTLSPMMSSKLLKSNAKP---------TWMEERVEHTLGKVNRVYEYMLDLVMLNR 529 +VAL L+P + + LLK + W +H+ VN + ++ Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHS---VNHYTNSVGKILGSTG 538 Query: 530 KSMLAFAVVIFSTLPFLFNSLSSELTPNEDKGAFIAIGNAPSSVNVDYIQNAMQP----Y 585 + +L +A+++ + LF L S P ED+G F+ + P+ + Q + Y Sbjct: 539 RYLLIYALIVAGMV-VLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYY 597 Query: 586 MKNVMETPEVSF---GMSIAGAPTSNSSLNIITLKDWKERSRK---QSAIMNEINEKAKS 639 +KN E F G S +G N+ + ++LK W+ER+ A+++ + Sbjct: 598 LKNEKANVESVFTVNGFSFSG-QAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGK 656 Query: 640 IPEVSVSAFNIPEIDTG--EQGAPVSIVLKTAQDYKSLANTAEKFLS-AMKASGKFIYTN 696 I + V FN+P I G ++ + + +L + L A + + Sbjct: 657 IRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVR 716 Query: 697 LDLTYDTAQMTISVDKEKAGTYGITMQQISNTLGSFLSGATVTRVDVDGRAYKVISQVKR 756 + DTAQ + VD+EKA G+++ I+ T+ + L G V GR K+ Q Sbjct: 717 PNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADA 776 Query: 757 DDRLSPESFQNYYLTASNGQSVPLSSVISMKLETQPTSLPRFSQLNSAEISAVPMPGISS 816 R+ PE Y+ ++NG+ VP S+ + L R++ L S EI PG SS Sbjct: 777 KFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSS 836 Query: 817 GDAIAWLQQQANDNLPQGYTYDFKSEARQLVQEGNALTTTFILAVVIIFLVLAIQFESIR 876 GDA+A ++ A+ LP G YD+ + Q GN ++ V++FL LA +ES Sbjct: 837 GDAMALMENLAS-KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 877 DPMVIMISVPLAVSGALVSLNILSFFSIAGTTLNIYSQVGLITLVGLITKHGILMCEVAK 936 P+ +M+ VPL + G L++ + ++Y VGL+T +GL K+ IL+ E AK Sbjct: 896 IPVSVMLVVPLGIVGVLLAAT------LFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAK 949 Query: 937 EEQLNYGKTRIEAITHAAKVRLRPILMTTAAMVAGLIPLLYATGAGAVSRFSIGIVIVAG 996 + GK +EA A ++RLRPILMT+ A + G++PL + GAG+ ++ ++GI ++ G Sbjct: 950 DLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGG 1009 Query: 997 LSIGTIFTLFVLPVVYSYIATEHK 1020 + T+ +F +PV + I K Sbjct: 1010 MVSATLLAIFFVPVFFVVIRRCFK 1033
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 143 bits (361), Expect = 1e-39 Identities = 91/397 (22%), Positives = 171/397 (43%), Gaps = 17/397 (4%) Query: 23 LSLATFMQVLDSTIANVAIPTIAGDLGASFSQGTWVITSFGVANAISIPITGWLAKRFGE 82 L + +F VL+ + NV++P IA D + WV T+F + +I + G L+ + G Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 83 VRLFLVSTFLFVVSSWLCGIADSLEALIIF-RVIQGAVAGPVIPLSQSLLLNNYPPEKRG 141 RL L + S + + S +L+I R IQGA A L ++ P E RG Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138 Query: 142 MALAFWSMTIVVAPIFGPILGGWISDNIHWGWIFFINVPIGLLVVLISWKILGSRESEIV 201 A + + GP +GG I+ IHW + + +P+ + ++ + + + ++ + Sbjct: 139 KAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPM-ITIITVPFLMKLLKKEVRI 195 Query: 202 HQPIDKVGLVLLVLGVGCLQLMLDQGREQDWFNSNEIIILAVVAVVCLIALVIWELTDDN 261 D G++L+ +G+ L F ++ I +V+V+ + V + Sbjct: 196 KGHFDIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVTD 245 Query: 262 PVVDISLFHSRNFSVGCLCTSLAFLIYLGSVVLIPLLLQQVFHY-TATWAGLAASPVGLF 320 P VD L + F +G LC + F G V ++P +++ V TA + P + Sbjct: 246 PFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMS 305 Query: 321 PILLSPIIGRFGYKIDMRILVTISFIVYAITFYWRAVTFEPSMTFVDVALPQLVQGLAVS 380 I+ I G + ++ I +++F + E + F+ + + ++ GL+ + Sbjct: 306 VIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFT 365 Query: 381 CFFMPLTTITLSGLPAHKMASASSLFNFLRTLAGSVG 417 ++TI S L + + SL NF L+ G Sbjct: 366 K--TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTG 400
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 80.3 bits (198), Expect = 1e-18 Identities = 43/287 (14%), Positives = 87/287 (30%), Gaps = 35/287 (12%) Query: 91 ELDDTNAKLSFEQAKSNLANAVRQVE----QLGFTVQQLQSAVHANEISLAQAQGNLARR 146 E + ++ S N Q E + + + ++ E + L Sbjct: 181 EEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDF 240 Query: 147 VQLEKMGAIDKESFQHAKEAVELAKANLNASKNQLAANQALLRNVPLR------------ 194 L AI K + + A L K+QL ++ + + Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI 300 Query: 195 ------EQPQIQNAINSLKQAWLNLQRTKIRSPIDGYVARRNVQ-VGQAVSVGGALMAVV 247 I L + Q + IR+P+ V + V G V+ LM +V Sbjct: 301 LDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIV 360 Query: 248 -SNEQMWLEANFKETQLTNMRIGQPVKIHFDLYGKNK--EFDGVINGIEMGTGNAFSLLP 304 ++ + + A + + + +GQ I + + + G + I + Sbjct: 361 PEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA-------I 413 Query: 305 SQNATGNWIKVVQRVPVRIKLDPQQFTETPLRIGLSATAKVRISDSS 351 G V+ + + PL G++ TA+++ S Sbjct: 414 EDQRLGLVFNVIISIEENCLSTGNK--NIPLSSGMAVTAEIKTGMRS 458
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 36.3 bits (84), Expect = 1e-04 Identities = 33/133 (24%), Positives = 48/133 (36%), Gaps = 22/133 (16%) Query: 129 IPVINENDAVATAEIKVGDNDNLSALVAILVQAEQLYLLTDQQGLFDSDPRKNPEAKLIP 188 +PVI E+ + E V D D +A V A+ +LTD G E L Sbjct: 197 VPVILEDGEIKGVE-AVIDKDLAGEKLAEEVNADIFMILTDVNGAA-LYYGTEKEQWLRE 254 Query: 189 V-VEQITDHIRSIAGGSGTNLGTGGMMTKIIAADVATRSGIETIIAPGNRPNVIADL--- 244 V VE++ + + G M K++AA G +IA L Sbjct: 255 VKVEELRKYYEE------GHFKAGSMGPKVLAAIRFIEW--------GGERAIIAHLEKA 300 Query: 245 --AYEQNIGTKFI 255 A E GT+ + Sbjct: 301 VEALEGKTGTQVL 313 Score = 33.6 bits (77), Expect = 9e-04 Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Query: 3 KKTIVVKFGTSTLTQGSPKLNSPHMMEIVR----QIAQLHNDGFRIVIV 47 K +V+ G + L Q K + MM+ VR QIA++ G+ +VI Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVIT 50
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 26.4 bits (58), Expect = 0.021 Identities = 12/61 (19%), Positives = 27/61 (44%), Gaps = 8/61 (13%) Query: 19 EQSPFAKIIKK---GLAINELNQ-KFNRIFPQEFHGKFRIGNITDHLIFIEV----SNAI 70 + F +++K I +++Q +RI +F +G + + + IE+ SN Sbjct: 71 KAPMFCMVLRKYISNAKIVDIHQINQDRIVVIDFESTDELGFNSIYSLIIEIMGRHSNMT 130 Query: 71 V 71 + Sbjct: 131 L 131
>PF06580#Sensor histidine kinase Length = 349 Score = 26.0 bits (57), Expect = 0.032 Identities = 11/49 (22%), Positives = 24/49 (48%), Gaps = 4/49 (8%) Query: 56 KVAREVQRQAIPQPSISRQTEK---QPKIQPHFLADVLN-LSAPIRAGP 100 K ++ + S++++ + + +I PHF+ + LN + A I P Sbjct: 142 KNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDP 190
>SECA#SecA protein signature. Length = 901 Score = 1332 bits (3449), Expect = 0.0 Identities = 611/897 (68%), Positives = 731/897 (81%), Gaps = 1/897 (0%) Query: 1 MSILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQ 60 + +LT++FGSRN+R LR+++K V IN MEP E LSD+ELK KT EFR RL GE L+ Sbjct: 3 IKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLEN 62 Query: 61 ILPEAFATVREASKRVLGMRHFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALE 120 ++PEAFA VREASKRV GMRHFDVQL+GGMVL RCIAEMRTGEGKTLTATLP YL AL Sbjct: 63 LIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALT 122 Query: 121 GKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLSPEEKRAAYAADITYATNSEL 180 GKGVHVVTVNDYLA+RDAE NRPLFEFLG++VG+N+PG+ KR AYAADITY TN+E Sbjct: 123 GKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEY 182 Query: 181 GFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAENSSELYIAVNKL 240 GFDYLRDN+A S EER QR L YALVDEVDSILIDEARTPLIISG AE+SSE+Y VNK+ Sbjct: 183 GFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKI 242 Query: 241 IPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLITQGLMPEGDSLYSPS 300 IP LI+QEKED+E +QGEG F++D KS+Q +LTERG +E+ L+ +G+M EG+SLYSP+ Sbjct: 243 IPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPA 302 Query: 301 RIVLLHHVMAALRAHTLFEKDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEG 360 I+L+HHV AALRAH LF +DVDYIVKDGE++IVDEHTGRTM GRRWSDGLHQA+EAKEG Sbjct: 303 NIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEG 362 Query: 361 VDVKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQQIYGLETVVIPTNRPMIRDD 420 V +++ENQT+ASI++QNYFRLYE+LAGMTGTADTEAFEF IY L+TVV+PTNRPMIR D Sbjct: 363 VQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKD 422 Query: 421 RTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAK 480 D+++ E K AIIEDIK+ + QPVLVGTIS+EKSE +S L KAGIKHNVLNAK Sbjct: 423 LPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAK 482 Query: 481 FHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWE 540 FH EA IVA+AG+P+AVTIATNMAGRGTDI+LGG+W+A+ A LENPT EQIE +KA+W+ Sbjct: 483 FHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQ 542 Query: 541 KNHEIVMKAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEG 600 H+ V++AGGLHIIGTERHESRRIDNQLRGRSGRQGD GSSRFYLS+ED LMRI+ ++ Sbjct: 543 VRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDR 602 Query: 601 KLNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGRKNLLEYDDVANDQRHAIYEQ 660 +MRK GEA+E + K IA+AQ KVE+ +FD RK LLEYDDVANDQR AIY Q Sbjct: 603 VSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQ 662 Query: 661 RNHLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISN 720 RN LLD D+SETIN+IR DVF ID YIPPQSLEE WDI GL+ERL +F ++LPI+ Sbjct: 663 RNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 721 WLEEDNNLHEESLCERIVEIAEKEYKEKEALVGEDAMRHFEKGVMLQTLDELWKEHLASM 780 WL+++ LHEE+L ERI+ + + Y+ KE +VG + MRHFEKGVMLQTLD LWKEHLA+M Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782 Query: 781 DYLRQGIHLRGYAQKDPKQEYKKESFRMFTEMLDSLKHQVITTLTRVRVRTQEEMEEAER 840 DYLRQGIHLRGYAQKDPKQEYK+ESF MF ML+SLK++VI+TL++V+VR EE+EE E+ Sbjct: 783 DYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQ 842 Query: 841 ARQEMAARINQ-NNLPVDENSQTTQNSETEDYSDRRIGRNEPCPCGSGKKYKHCHGS 896 R+ A R+ Q L ++ + +R++GRN+PCPCGSGKKYK CHG Sbjct: 843 QRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGR 899
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 28.7 bits (64), Expect = 0.022 Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 3/75 (4%) Query: 58 HLQLYLERG--AAKVIGTDLSEKMLEQAEKDLQKCGQFSGRF-SLYHLPIEKLAELPESH 114 H L LE G AK I LS K E + +++ + L +K ++P Sbjct: 139 HAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEK 198 Query: 115 FDVITSSFAFHYIEN 129 ++TS AF Y Sbjct: 199 KLIVTSEGAFKYFSK 213
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.011 Identities = 9/16 (56%), Positives = 12/16 (75%) Query: 54 VVGESGCGKSTLARAI 69 + GESG GK +ARA+ Sbjct: 165 ITGESGTGKELVARAL 180