>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 73.9 bits (181), Expect = 4e-16 Identities = 53/191 (27%), Positives = 95/191 (49%), Gaps = 18/191 (9%) Query: 429 ESEKWGIDGFSVWRNSLSSREIQAIRDYTDIWHYGNMNGYLR--GSVEKLAPDNAERIKN 486 + + WG + +S W N L+ E+ + DY Y +N YL G + P+ ++ N Sbjct: 260 KGDLWGKENYSDWSNKLTPNELADVNDYMR-GGYTAINNYLISNGPLNNPNPELDSKVNN 318 Query: 487 LSSALEKAELPDNIILYRGTSSEILD--------NFLDLKNLN--YQNLVGKTIEEKGFM 536 + +AL+ +P N+I+YR + + +F ++N++ + GK I F+ Sbjct: 319 IENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFI 378 Query: 537 STT--TISNQTFSGN-VTMKINAPKGSKGAYLAHFSETPEEAEVLFNIGQKMLIKEVTEL 593 ST+ +++ F+ + ++IN PK S GAYL+ E EVL N G K I +V Sbjct: 379 STSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSY 438 Query: 594 -NGKI-EIIVD 602 +G + ++I+D Sbjct: 439 KDGTVTKLILD 449
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 28.2 bits (63), Expect = 0.030 Identities = 15/90 (16%), Positives = 34/90 (37%), Gaps = 21/90 (23%) Query: 62 LVLLALLCYIILYPQKMTIRFQNLQYLLYICCFQFLVFMVIRYFYSNLIYGIQNMVSLTA 121 +VLL++L +II+ + +++ + + + Sbjct: 147 VVLLSILIWIIIKG---------------------NLVTLLQLPTCGIECITPLLGQILR 185 Query: 122 QTLVASYVFLLVLWILALIFFYFHFRKKLR 151 Q +V V +V+ I F Y+ + K+L+ Sbjct: 186 QLMVICTVGFVVISIADYAFEYYQYIKELK 215
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 32.5 bits (74), Expect = 0.004 Identities = 20/117 (17%), Positives = 46/117 (39%), Gaps = 8/117 (6%) Query: 134 IRVVNYINMLSDLLSNGLINLISDILSVIVTLGFM------LMIDPVLTLYSLALIPVLF 187 ++ + +I L+ ++ +++ +I+ G + P L LAL F Sbjct: 42 VQTLVFITSLT--FIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFF 99 Query: 188 VIVMVIKTAQRKAYQVLSNKQSNMNAYIHESIAGIKVTQSFSREEENFEIFTEVSNE 244 ++ VI AYQ S ++ +M + + ++ E + +F ++N Sbjct: 100 IMSPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANT 156
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.9 bits (67), Expect = 9e-04 Identities = 13/66 (19%), Positives = 25/66 (37%), Gaps = 1/66 (1%) Query: 1 MEYKNGENR-IYAVNDEGVEVGEVTFVPTGEDMFIIDHTGVDDAARGQGIAQELVKRAVE 59 + Y E + + E +G + +I+ V R +G+ L+ +A+E Sbjct: 57 VSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIE 116 Query: 60 KAKSEG 65 AK Sbjct: 117 WAKENH 122
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 43.8 bits (103), Expect = 1e-06 Identities = 20/88 (22%), Positives = 24/88 (27%), Gaps = 8/88 (9%) Query: 673 TTPVSFEIVAGETDPIVKVTKENTLVPPTPVPPTPVPPTPVPPTPVPPTPLPPVPYEPTV 732 P+S +V P P V P P P P PV E Sbjct: 42 AQPISVTMVTPADLE--------PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK 93 Query: 733 PPTKPEVPVTPKKTENSEDSPKTTPIRI 760 P KP+ K E + K R Sbjct: 94 PKPKPKPKPVKKVQEQPKRDVKPVESRP 121
>PF05043#Transcriptional activator Length = 493 Score = 49.6 bits (118), Expect = 2e-08 Identities = 50/231 (21%), Positives = 97/231 (41%), Gaps = 15/231 (6%) Query: 4 SERQRSLLEKLNDSQKTVTAKALSEMLGVSSKTVRNDIMQINQSFSSTIIASKAGKGYFL 63 S RQ LLE L + ++ L+E+L + + V++D+ + +F I S + Sbjct: 9 SHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHSSTNGIRII 68 Query: 64 MPNEQLSQMNLTK-NNENLHFELLRHIIEQDHTNFYDLADQFFISESTLARIIKELNIVI 122 ++ +M + HF +L I + + +F+IS S+L RII ++N VI Sbjct: 69 NTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRIISQINKVI 128 Query: 123 AEKDESLCIIRKNNELLTEGGEEEKRRIFNLFLNQEIENHQLSLDKYADYFDYCNLKQLS 182 + + + G E R F E + ++ F+ + + LS Sbjct: 129 KRQFQFEVSLTPV----QIIGNERDIRYFFAQYFSE----KYYFLEWP--FENFSSEPLS 178 Query: 183 ELIIAYHKKHEFFMNDFSTISFILHIAVLIERISMGSYIERTALLEQDKTS 233 +L+ +K+ F MN + L + + RI G ++E +++D + Sbjct: 179 QLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME----VDKDSFN 225
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.8 bits (67), Expect = 0.025 Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 8/78 (10%) Query: 31 DYYLHEAGLENGDVASDHYHRYEEDIRMMKEGGQNSYRFSLSWPRIIKNRQGDINLKGIE 90 + H+ L + + +D + + R+ + + R+SL P D NL G Sbjct: 53 GFQFHKIDLADREGMTDLFASGHFE-RVFISPHRLAVRYSLENPHAYA----DSNLTG-- 105 Query: 91 FYQNLLDTCKKYDIEPFV 108 + N+L+ C+ I+ + Sbjct: 106 -FLNILEGCRHNKIQHLL 122
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.0 bits (67), Expect = 0.016 Identities = 17/89 (19%), Positives = 25/89 (28%) Query: 253 HNEKKRMELHFRKLEKQKLELEKKNKELISENYNLDLEIKNKHTVIEKLSKNKMEVEANK 312 N + LE +K L + +L I+ L K +EA + Sbjct: 133 MNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQ 192 Query: 313 ELLKICKIENGNLIKKVSALNFELVKMKE 341 L+ N SA L K Sbjct: 193 AELEKALEGAMNFSTADSAKIKTLEAEKA 221
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.4 bits (66), Expect = 0.011 Identities = 14/70 (20%), Positives = 23/70 (32%), Gaps = 7/70 (10%) Query: 132 GVGPIFPTISKADAEPVSGTAILEE---IRRAGITIPIVGIGGINETNSAEVLTAGADGV 188 G+ I+ I D LEE +R G PI+ + G E+ Sbjct: 42 GIERIWSAIGATDG---FALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQ-HRLT 97 Query: 189 SVISAITQSD 198 + + + Q Sbjct: 98 TCVHSNWQLK 107
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 36.1 bits (83), Expect = 1e-04 Identities = 23/106 (21%), Positives = 35/106 (33%), Gaps = 9/106 (8%) Query: 268 PVTPPKNDPEPDNPEEPVTPVDPATPIPDEPSTPTDPATPEKPEITTPENPESTVVEADS 327 P P +PEP+ P P + I P KP E P+ V +S Sbjct: 63 PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP---KPVKKVQEQPKRDVKPVES 119 Query: 328 SENEPEKSADSKIVNNPIQITSQATKTATKQAKSSATKTTLPLPKA 373 P ++ P ++TS AT + +S L + Sbjct: 120 RPASPFEN------TAPARLTSSTATAATSKPVTSVASGPRALSRN 159
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 36.2 bits (83), Expect = 0.002 Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 10/119 (8%) Query: 1015 VTVNKDPAPIISA------KTEITYDKFSKKTEAAFLDDIDADTNDGSIVTSNFATAVN- 1067 V VNK+P +I + + EI +D K E + + D DG SN A A + Sbjct: 769 VHVNKEPKAVIKSDSSVIVEEEINFDGTESKDEDGEIKAYEWDFGDGE--KSNEAKATHK 826 Query: 1068 LDKAGDYTVTLNSINSDGVAGTPTAIIVHVEKEKIATISTNTAQQ-YEKYAKINETQFL 1125 +K G+Y V L +++G T + I VE + + I+ + +EK +I ++ L Sbjct: 827 YNKTGEYEVKLTVTDNNGGINTESKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNML 885 Score = 33.9 bits (77), Expect = 0.007 Identities = 44/195 (22%), Positives = 80/195 (41%), Gaps = 21/195 (10%) Query: 1313 TNFKTAMSYTVTLNAVNEDGISAEPVAVTVTINKEPAAALKADA------EVSYAKNEAV 1366 N K + + V G++ + V +NKEP A +K+D+ E+++ E+ Sbjct: 742 VNHKVDGNGNYVYDVVFH-GMNTDTNT-DVHVNKEPKAVIKSDSSVIVEEEINFDGTESK 799 Query: 1367 TESDFFKDVHLE-GTEAPST-AKATSNFDSVVDRSKTGDYTVTINATNEDGAVSTPIEVI 1424 E K + G S AKAT ++ KTG+Y V + T+ +G ++T + I Sbjct: 800 DEDGEIKAYEWDFGDGEKSNEAKATHKYN------KTGEYEVKLTVTDNNGGINTESKKI 853 Query: 1425 VHIEAESAPVITANA-EVKYNKHEQTDERRFL----YDSEAKIDEANVEIKTDFAEKVDI 1479 +E + VI + + K Q + L E D+ ++ K+ + Sbjct: 854 KVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKGNVKITL 913 Query: 1480 NKVGTYTVTLTATNE 1494 N + + +T T E Sbjct: 914 NNLNSVGITWTLYKE 928
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 135 bits (342), Expect = 4e-41 Identities = 83/254 (32%), Positives = 126/254 (49%), Gaps = 12/254 (4%) Query: 12 ITDKVAVVTGAASGIGKAMAELFSEKGAYVVLLDIKED--VKDVAAKINPSRTL-ALQVD 68 I K+A +TGAA GIG+A+A + +GA++ +D + K V++ +R A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 69 ITKKENIEKVVAEIKKVYPKIDILANSAGVALLEKAEDLPEEYWDKTMELNLKGSFLMAQ 128 + I+++ A I++ IDIL N AGV L +E W+ T +N G F ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 129 IIGREMIATGGGKIVNMASQASVIALDKHVAYCASKAAIVSMTQVLAMEWAPYNINVNAI 188 + + M+ G IV + S + + AY +SKAA V T+ L +E A YNI N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 189 SPTVILTELGKKAWAGQVGED---------MKKLIPAGRFGYPEEVAACALFLVSDAASL 239 SP T++ WA + G + K IP + P ++A LFLVS A Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 240 ITGENLIIDGGYTI 253 IT NL +DGG T+ Sbjct: 246 ITMHNLCVDGGATL 259
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.0 bits (67), Expect = 0.014 Identities = 34/138 (24%), Positives = 51/138 (36%), Gaps = 9/138 (6%) Query: 150 TQITVQSNIERIVGGAGEDTV-IARVGEAVVSTVG---ETREHTDVLENPNSISK--KVQ 203 T IT +NI+ V + IARV EA V + V EN SK + Sbjct: 995 TNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN 1054 Query: 204 EQGLGDGTAYTILSIDIAEMRIGDNIKAKLDIEKANADMEVAQAAASKRKAEAIALEQEN 263 EQ + TA A+ + N + E A + E + ++ K A ++E Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTN---EVAQSGSETKETQTTETKETATVEKEEK 1111 Query: 264 RAAVVAAEAEVPRALSRA 281 EVP+ S+ Sbjct: 1112 AKVETEKTQEVPKVTSQV 1129
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 42.6 bits (100), Expect = 7e-08 Identities = 20/96 (20%), Positives = 37/96 (38%), Gaps = 9/96 (9%) Query: 50 EMVGGVTAKISYGE-LHVSLLSVDPSTQGSGVGTELMAQIERYGRANSCHHISLTTFSYQ 108 +G + + ++ + ++V + GVGT L+ + + + N + L T Sbjct: 75 NCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDIN 134 Query: 109 AP--EFYRKCGFTELGRV-----KDFPIKGEEKYFF 137 FY K F +G V +FP E F+ Sbjct: 135 ISACHFYAKHHFI-IGAVDTMLYSNFPTANEIAIFW 169
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 32.9 bits (75), Expect = 0.004 Identities = 29/157 (18%), Positives = 59/157 (37%), Gaps = 22/157 (14%) Query: 21 SHLSAQKLSQDLHISERTIRTDIAKLTEFLESHGATITLTRGAGYKIEILDPTVFQAFQA 80 S L ++++ ++ + +L F + I + Sbjct: 57 SSLPITEVAEKTGLTFLQLNHYCEELNAFFPDS-----------LSMTIQKRMI----SC 101 Query: 81 EKNKPKNADYF-DLDNPEERVKYEIFLLLSSADYIKLEDLADTIFASRATISNDMKQVRK 139 + P Y L ++ FL+ + + L D A + F S ++ + + Sbjct: 102 QFTHPSKETYLYQLYASSNVLQLLAFLIKNGSHSRPLTDFARSHFLSNSSAYRMREALIP 161 Query: 140 VIASYDLTLVSKPGSGVKIVGDEEKMRYALTALIASK 176 ++ +++L L KIVG+E ++RY L AL+ SK Sbjct: 162 LLRNFELKLSKN-----KIVGEEYRIRY-LIALLYSK 192
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.3 bits (78), Expect = 5e-04 Identities = 26/142 (18%), Positives = 48/142 (33%), Gaps = 22/142 (15%) Query: 121 ENGAFSLSVNELDKAQDAVLSIVIDGQTKEQTLKLALTPAYETKIAEKAEAERV------ 174 NG + L E++K V + I Q A P+ + E A + Sbjct: 974 VNGRYDLYNPEVEKRNQTVDTTNITTPNNIQ----ADVPSVPSNNEEIARVDEAPVPPPA 1029 Query: 175 -------AAEKAEAERVERERVAAEEKRAADAKIAAEKKAEEAR--VAAEKKAAEEKRVA 225 AE + E + V E+ A + + A+EA+ V A + E + Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSG 1089 Query: 226 AERSKA---AAAQPDTSNEQGQ 244 +E + + T ++ + Sbjct: 1090 SETKETQTTETKETATVEKEEK 1111
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 94.7 bits (235), Expect = 2e-25 Identities = 60/223 (26%), Positives = 102/223 (45%), Gaps = 6/223 (2%) Query: 3 IKNKVIIITGASSGIGKATALLLAEKGAKLVLAARRVEKLEKIVQTIKANSGEAIFAKTD 62 I+ K+ ITGA+ GIG+A A LA +GA + EKLEK+V ++KA + A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 63 VTKREDNKKLVELAIERYGKVDAIFLNAGIMPNSPLSALKEDEWEQMIDINIKGVLNGIA 122 V ++ G +D + AG++ + +L ++EWE +N GV N Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 123 AVLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMESAQEGTNIRTV 182 +V + ++SG I+ S A Y ++K A + L +E A NIR Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA--EYNIRCN 183 Query: 183 TIYPAAINTELLETI--TDKETEQGMTSLYKQY--GITPDRIA 221 + P + T++ ++ + EQ + + + GI ++A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLA 226
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 34.3 bits (78), Expect = 0.007 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 12/109 (11%) Query: 1594 NKPGKYEVTITATDTKGNQTTKEITVQVSKDKPV---ITADPKISYQGKIEVTEANFLSG 1650 NK G+YEV +T TD G T+ ++V +DKPV ++P ++ ++ ++N L Sbjct: 828 NKTGEYEVKLTVTDNNGGINTESKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVK 887 Query: 1651 VHAEVTDELDGDVKITSDFAEKVDFNKVGTYTVTLNAKDEYGNTAEPVK 1699 D D D K G +TLN + G T K Sbjct: 888 GTLSEEDYSDK---------YYFDVAKKGNVKITLNNLNSVGITWTLYK 927
>PF05043#Transcriptional activator Length = 493 Score = 58.4 bits (141), Expect = 3e-11 Identities = 54/247 (21%), Positives = 102/247 (41%), Gaps = 38/247 (15%) Query: 1 MREYLDSKSQKKVALLEKIF--YAENHTSTQEELLN-----------DLNITYPTLISTI 47 MR+ L KS +++ LLE +F H S ELLN + +P LI Sbjct: 1 MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHS 60 Query: 48 KTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLAS 107 T I+++ D+ I+++ + + + S F ILE + Sbjct: 61 ST----------NGIRIINT-----------DDSDIEMVYHHFFKHSTHFSILEFIFFNE 99 Query: 108 FPNLQALAKKVHVSYSGIKKEIKELNEELRER-NLSISTGNQVEITGDEFSLRIFYAFLF 166 +++ K+ ++S S + + I ++N+ ++ + +S V+I G+E +R F+A F Sbjct: 100 GCQAESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTP-VQIIGNERDIRYFFAQYF 158 Query: 167 LVTYSGDRWPFSFVQYDEITDLLESCPKEIYRANSIDKGMMIHYYVAMHLLRDRMN--CQ 224 Y WPF + ++ LLE KE ++ M+ + +L R + + Sbjct: 159 SEKYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME 218 Query: 225 IDTTRQF 231 +D Sbjct: 219 VDKDSFN 225
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 42.7 bits (100), Expect = 2e-07 Identities = 14/48 (29%), Positives = 22/48 (45%) Query: 7 TKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLL 54 T++ I + L + S+ +I G+ R Y+HF DK DL Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 129 bits (325), Expect = 6e-35 Identities = 92/400 (23%), Positives = 168/400 (42%), Gaps = 14/400 (3%) Query: 25 FIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQWFTTRGLFF 84 F + +E LN++L D+ F+ A+ W+ T ++LT I + G L + L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 85 TAVSFSIAGTLIAALSPTFAMLMI-GRVVQAVGTALLLPLMFNTILLIFPEHKRGSAMGM 143 + + G++I + +F L+I R +Q G A L+ + P+ RG A G+ Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 144 IGLVIMFAPAVGPTISGLILENLTWNWIFWISLPFLIIALLFGMKFMQNVSVVTKPKIDI 203 IG ++ VGP I G+I + W+++ I + II + F MK ++ + DI Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITVPFLMKLLKKEVRIKGH-FDI 201 Query: 204 LSIILSTLGFGGVVFAFSSAGESGWGSATVLVSIIVGGIALGLFVWRQLTMEKPLMDLKV 263 IIL G+VF V V ++ +FV + P +D + Sbjct: 202 KGIILM---SVGIVFFMLFTTSYSISFLIVSV------LSFLIFVKHIRKVTDPFVDPGL 252 Query: 264 FKYPMFTLGLILVFISFMMILSTMILLPLYLQNSLALAAFSAG-LVLLPGGVLNGLMSPF 322 K F +G++ I F + + ++P +++ L+ G +++ PG + + Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 323 TGRLFDAYGPRALVIPGFIVAVVALFFLTRIEVGTSALTIIVLHSVLMIGISMVMMPAQT 382 G L D GP ++ G V+ + + TS I++ VL G+S T Sbjct: 313 GGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFTKTVIST 371 Query: 383 NGLNQLPPKLYPDGTAIMNTLQQVSGAIGTAVAITIMSAG 422 + L + G +++N +S G A+ ++S Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 45.7 bits (108), Expect = 1e-08 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 14/107 (13%) Query: 52 EEAEYIEESDKNPGSVMLLCFIDDELASISQLIGHIKKRELHTSELA---ISIRKKYWGL 108 + Y+EE K L ++++ IG IK R I++ K Y Sbjct: 55 MDVSYVEEEGK----AAFLYYLENNC------IGRIKIRSNWNGYALIEDIAVAKDYRKK 104 Query: 109 GIGTICMEELIKYAKSSEYLKLIYLEVVTENKRAINLYKKFGFIEAG 155 G+GT + + I++AK + + L LE N A + Y K FI Sbjct: 105 GVGTALLHKAIEWAKENHFCGL-MLETQDINISACHFYAKHHFIIGA 150
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 32.0 bits (73), Expect = 0.005 Identities = 35/206 (16%), Positives = 65/206 (31%), Gaps = 46/206 (22%) Query: 59 GEVFSSPVAIIMLLILALLILLFVYYELGFFIMMAIYQLRGESYTFFKIIQRLNVKAKYF 118 G+V S + LI+AL +L + F + + E + Y Sbjct: 21 GQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQ-----SYLPFSQALSYV 75 Query: 119 LSYQAIYFLLYFFLLLPIAGLSL-------------------------PITITENLYLPH 153 + + F F LL +A L PI + ++ Sbjct: 76 VDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKINPIEGAKRIFSIK 135 Query: 154 FITDELMKTTTGTWLYVIAIAIIFYISARLVFALPYFIEDKSLKISGAIRKSWKYPQKHL 213 + E +K+ L V+ ++I+ +I + L G L Sbjct: 136 SLV-EFLKSI----LKVVLLSILIWI-----IIKGNLVTLLQLPTCGI------ECITPL 179 Query: 214 FFMLLKWVLIIVAIGFLVSIIATIIM 239 +L+ +++I +GF+V IA Sbjct: 180 LGQILRQLMVICTVGFVVISIADYAF 205
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 25.8 bits (56), Expect = 0.045 Identities = 12/74 (16%), Positives = 28/74 (37%), Gaps = 3/74 (4%) Query: 53 QVESKLNGVSMPISEEISRDKLKDAIKQAQAGKIDFEIFIKLAGLAGVRLWEADLSAMKV 112 + S V +++E+ + +D++K+ + + A + +R MK Sbjct: 38 ALRSLATTVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKASMDELRQAAES---MKR 94 Query: 113 TYIDNTGNDLVIEP 126 +Y+ N E Sbjct: 95 SYVANDPEKASDEA 108
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 167 bits (425), Expect = 1e-53 Identities = 79/239 (33%), Positives = 132/239 (55%) Query: 14 FIVIFAISLVVFWPGVNVHAESWMDSLGVNGTDGVNSSVALFVLVTVLSLSASIVLMFTH 73 + + + L + P G + V V +T L+ +I+LM T Sbjct: 4 LLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTS 63 Query: 74 FTYCIIVLGLTRQGLGATNLPPNQVLVGLALFLSLFMMQPLITAWYDDVYKPSQKEEWSA 133 FT IIV GL R LG + PPNQVL+GLALFL+ F+M P+I Y D Y+P +E+ S Sbjct: 64 FTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISM 123 Query: 134 SKVWDETQPLLTKYVAENTYKHDINMMLKAEGEDPVTKKEDAPLMALMPAFILTQITQGF 193 + ++ L +++ T + D+ + + P+ E P+ L+PA++ +++ F Sbjct: 124 QEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAF 183 Query: 194 LTGMFIYLAFIFIDLIVSTLLMYLGMMMVPPMTISLPFKILVFIFIGGYGLITNMIFQT 252 G I++ F+ IDL+++++LM LGMMMVPP TI+LPFK+++F+ + G+ L+ + Q+ Sbjct: 184 QIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQS 242
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 42.8 bits (101), Expect = 5e-09 Identities = 15/76 (19%), Positives = 34/76 (44%) Query: 6 ITQIFQDFFYSGLALILPVSLICIVVVIVVAILMAMMQIQDQSLTFLPKIVAFVVALFIL 65 + Y L L +++ ++ ++V + + Q+Q+Q+L F K++ + LF+L Sbjct: 4 LVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLL 63 Query: 66 GPWMFEHMTDLFVGIF 81 W E + + Sbjct: 64 SGWYGEVLLSYGRQVI 79
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 94.0 bits (234), Expect = 3e-25 Identities = 51/230 (22%), Positives = 107/230 (46%), Gaps = 1/230 (0%) Query: 12 VFSRVASFLFFFPLLKGRNIPNSVKVVFGMAISIPVATWVDVSGITTLPD-LLLRVTSEV 70 RV + + P+L R++P VK+ M I+ +A + + + L ++ Sbjct: 19 PLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVPVFSFFALWLAVQQI 78 Query: 71 VFGLALAKLVEIIAVIPKMAGFMIDYDLGFSQVNLIDPSYGTQNSITAAILDTFFVVIFL 130 + G+AL ++ + AG +I +G S +DP+ + A I+D +++FL Sbjct: 79 LIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLALLLFL 138 Query: 131 SLQGMDYLIYYLMKSFEFTASVSILFEKGFIDLLLGTLGFALASAVSIALPIMGSIFIVN 190 + G +LI L+ +F L + + +ALP++ + +N Sbjct: 139 TFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLALPLITLLLTLN 198 Query: 191 IILAFISKSAPQINIFMNAFIIKITFGIFILACAVPILSTVFKNLTDEMI 240 + L +++ APQ++IF+ F + +T GI ++A +P+++ ++L E+ Sbjct: 199 LALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIF 248
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 275 bits (704), Expect = 1e-92 Identities = 96/340 (28%), Positives = 183/340 (53%), Gaps = 2/340 (0%) Query: 4 DNKTEKATPRRIKKARNEGNVAKSKELNNAFSLLIVAGLLYFFGEMFIKNTIQAFVALLK 63 KTE+ TP++I+ AR +G VAKSKE+ + ++ ++ +L + + ++ + + + Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAE 62 Query: 64 QP--PKLANMESYSLFYLMEFGKVLMPIMVMVVIFGLMNYGVQVGILFSAKAVKPQFKRL 121 Q P + L+EF + P++ + + + ++ VQ G L S +A+KP K++ Sbjct: 63 QSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKI 122 Query: 122 NPANYFKRVFSVKGIVEVVKALLLITLLSYVAYIGFRDHLDTLISYTGQNWLYSLGQIFA 181 NP KR+FS+K +VE +K++L + LLS + +I + +L TL+ + Sbjct: 123 NPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQ 182 Query: 182 LFKNEFLALFLVIAVIGLLDFFYQRYDYKKGLRMSKQEIKDEMKDSEGRPEVKQRQRSIA 241 + + + + VI + D+ ++ Y Y K L+MSK EIK E K+ EG PE+K ++R Sbjct: 183 ILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQFH 242 Query: 242 RGLLQGSITKKMADATFVVNNPTHISVVMRYDKTKDHAPKLLVKGEDELALFIRQVADTD 301 + + ++ + + ++ VV NPTHI++ + Y + + P + K D +R++A+ + Sbjct: 243 QEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEE 302 Query: 302 GVPMITNRQLARSIYYTTNPDEYIQEDLYKDVIEVMKELM 341 GVP++ LAR++Y+ D YI + + EV++ L Sbjct: 303 GVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLE 342
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.2 bits (70), Expect = 0.007 Identities = 24/182 (13%), Positives = 60/182 (32%), Gaps = 9/182 (4%) Query: 7 EKMEIFKGNSKREIHKKIQLVTNEPYKITDERVTKLGIFKKQYEVTAVIMSEVAIADGRM 66 +E + ++ + + T + KI K + ++ ++ + + + Sbjct: 186 AALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADS 245 Query: 67 DFQETFQKSVVKTRPKTDDLLKKEKLLEMLAAGAELAQST------PLLEERKTQEEELS 120 +T + + +L K + + T L E+ E + Sbjct: 246 AKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQ 305 Query: 121 SMRLELAALNRELAVKMREEREQNSDFVKFLKGRGISDTYVADF---MQAGRKQFKQVET 177 + +L R+L +++ ++ K + IS+ + A R+ KQ+E Sbjct: 306 VLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEA 365 Query: 178 AH 179 H Sbjct: 366 EH 367
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 28.4 bits (63), Expect = 0.036 Identities = 5/32 (15%), Positives = 13/32 (40%) Query: 3 GLYIGAAGMMNYMQHIQVHSNNVANAQTPGFK 34 + +G+ + SNN+++ G+ Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYT 34
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 28.3 bits (63), Expect = 0.032 Identities = 13/50 (26%), Positives = 25/50 (50%), Gaps = 8/50 (16%) Query: 3 ITTIIGLVLAVIVIAGSFMIQNISLAMLFSAEALIVIILGTITAVMMAHP 52 +TT+ L L ++I G +I+ AM++ + GT ++V +A Sbjct: 262 MTTL--LALVPMLIWGGDVIRGFVFAMVWG------VFTGTYSSVYVAKN 303
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 57.6 bits (139), Expect = 1e-11 Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 16/129 (12%) Query: 148 ITIRDDILFQSGSAEL-SAGKREIAKEIGELFAQGKGTMEGIVSGHTDNVPISTSIYSSN 206 T++ D+LF A L G+ + + +L +V G+TD I + Y N Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR--IGSDAY--N 270 Query: 207 WELSVARAVNFMEAIIQENSEVNPGEFSARGYGEFRPVAKNDIAANREK---------NR 257 LS RA + ++ +I + + + SARG GE PV N +++ +R Sbjct: 271 QGLSERRAQSVVDYLISKG--IPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDR 328 Query: 258 RVEIMVRPI 266 RVEI V+ I Sbjct: 329 RVEIEVKGI 337
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 28.7 bits (64), Expect = 0.039 Identities = 21/130 (16%), Positives = 48/130 (36%), Gaps = 8/130 (6%) Query: 165 IYHYGYMSEIVEKQDKSDRNLRLLEKEVKNNKNSGFVHFNIGQEMNRLGNKKEALKEFSE 224 +Y + K + + + + L V ++ +S F +G +G A+ +S Sbjct: 39 LYSLAFNQYQSGKYEDAHKVFQALC--VLDHYDSRF-FLGLGACRQAMGQYDLAIHSYSY 95 Query: 225 AFRLRDHNHYIWAKLSAYHIAELLEQEKRYDESLAIIEEARVIWPNVPEFPLKKANILYV 284 + +H AE L Q+ E+ + + A+ + + EF + + Sbjct: 96 GAIMDIKEPR-----FPFHAAECLLQKGELAEAESGLFLAQELIADKTEFKELSTRVSSM 150 Query: 285 NHQLEDAKEI 294 ++ KE+ Sbjct: 151 LEAIKLKKEM 160
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 42.9 bits (101), Expect = 9e-07 Identities = 30/114 (26%), Positives = 47/114 (41%), Gaps = 13/114 (11%) Query: 175 TIFIAEDSQMLRQLLEDTLHEAGYTNLQFFANGREAQEHIFKLLKEQKEQTFENVNLLIT 234 TI +A+D +R +L L AGY +N I +L++T Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRIT-SNAATLWRWI-------AAGDG---DLVVT 53 Query: 235 DIEMPQMDGHHLTKVIKEDEIGRELPVVIFSSLITEDLEHKGAGVGADAQVSKP 288 D+ MP + L IK + +LPV++ S+ T K + GA + KP Sbjct: 54 DVVMPDENAFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105
>FLAGELLIN#Flagellin signature. Length = 507 Score = 127 bits (319), Expect = 2e-35 Identities = 84/277 (30%), Positives = 129/277 (46%), Gaps = 9/277 (3%) Query: 1 MKVNTNIISLKTQEYLRKNNEGMTQAQERLASGKRINSSLDDAAGLAVVTRMNVKSTGLD 60 +NTN +SL TQ L K+ ++ A ERL+SG RINS+ DDAAG A+ R GL Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLT 61 Query: 61 AASKNSSMGIDLLQTADSALSSMSSILQRMRQLAVQSSNGSFSDEDRKQYTAEFGSLIKE 120 AS+N++ GI + QT + AL+ +++ LQR+R+L+VQ++NG+ SD D K E ++E Sbjct: 62 QASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEE 121 Query: 121 LDHVADTTNYNNIKLLDQTATGAATQVSIQASDKANDLINIDLFNAKGLSAGTITLGSGS 180 +D V++ T +N +K+L Q Q+ IQ + I IDL S G G Sbjct: 122 IDRVSNQTQFNGVKVLSQD-----NQMKIQVGANDGETITIDLQKIDVKSLG----LDGF 172 Query: 181 TVAGYSALSVADADSSQQATEAIDELINNISNGRALLGAGMSRLSYNVSNVNNQSIATKA 240 V G +V D SS + D + R + +G V ++ A Sbjct: 173 NVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAA 232 Query: 241 SASSIEDADMAAEMSEMTKYKILTQTSISMLSQANQT 277 + D ++ K T + + A Sbjct: 233 NGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 75.9 bits (186), Expect = 1e-17 Identities = 51/294 (17%), Positives = 103/294 (35%), Gaps = 16/294 (5%) Query: 4 NTNIISLKTQEYLRKNNEGMTQAQERLASGKRINSSLDDAAGLAVVTRMNVKSTGLDAAS 63 +T ++ + Y+ N +T + + + AG A + G Sbjct: 217 DTTAPTVPDKVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGD 276 Query: 64 KNSSMGIDLLQTADSALSSMSSILQRMRQLAVQSSNGSFSDEDRKQYTAEFGSLIKELDH 123 G+ + + + V + + ++ + Sbjct: 277 TFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVAD----ITAGAANVDAATLQSSKN 332 Query: 124 VADTTNYNNIKLLDQTATGAATQVSIQASDKANDLINIDLFNAKGLSAGTITLGSGSTVA 183 V + D+T +A ++A++ I + A+ + + + Sbjct: 333 VYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKT 392 Query: 184 GYSA------------LSVADADSSQQATEAIDELINNISNGRALLGAGMSRLSYNVSNV 231 + + A S+ +ID ++ + R+ LGA +R ++N+ Sbjct: 393 MFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNL 452 Query: 232 NNQSIATKASASSIEDADMAAEMSEMTKYKILTQTSISMLSQANQTPQMLTQLI 285 N ++ S IEDAD A E+S M+K +IL Q S+L+QANQ PQ + L+ Sbjct: 453 GNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.4 bits (232), Expect = 9e-26 Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 1/115 (0%) Query: 3 KLLIVDDAMFMRTMIKNIVKDSDFEVVAEAENGLEAVKKYDEVKPDIVTLDITMPEMDGL 62 +L+ DD +RT++ + + ++V N + D+V D+ MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 EALAQIMAKDPSAKVIMCSAMGQQGMVVDAIKKGAKDFIVKPFQADRVLEALEKA 117 + L +I P V++ SA + A +KGA D++ KPF ++ + +A Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 35.6 bits (82), Expect = 5e-04 Identities = 14/67 (20%), Positives = 22/67 (32%), Gaps = 9/67 (13%) Query: 353 LIRNSVDHGAETVEVRRKNGKNETATINLKAFHSGNNVVIEIADDGAGINKRKVLEKAIA 412 L+ N + HG + I LK V +E+ + G+ K Sbjct: 263 LVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTG 314 Query: 413 -KNVVTR 418 +NV R Sbjct: 315 LQNVRER 321
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 59.9 bits (145), Expect = 5e-15 Identities = 20/81 (24%), Positives = 46/81 (56%), Gaps = 3/81 (3%) Query: 21 GREKGSIRQVD---NIGVNLIVRLGKKEMPVGDIAELSIGDVLEVEKKPGHKVEIFLDEK 77 G G+++ +D +I V L V LG+ M + ++ L+ G V+ ++ G ++I ++ Sbjct: 45 GDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGY 104 Query: 78 KVGIGEAILMDENFGIVISEI 98 + GE +++ + +G+ I++I Sbjct: 105 LIAQGEVVVVADKYGVRITDI 125
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.9 bits (64), Expect = 0.041 Identities = 33/202 (16%), Positives = 56/202 (27%), Gaps = 19/202 (9%) Query: 48 EADNEEQATIPLKEIAPSLVSAKLLDSEPETKLPSAPLELKEVKETLAAIAKQAIDQPKI 107 A N E A + + + ++ S ETK + E KE T+ K ++ K Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETK-ETQTTETKE-TATVEKEEKAKVETEKT 1119 Query: 108 DSAPQVAQ--PP------------EMNTPKEPT---KNTTREQQPPPELIMPTKDSPKLA 150 P+V P E +PT K + + P K++ Sbjct: 1120 QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV 1179 Query: 151 ENVAKNQPALAKLPQEKEAVQLFKASIKEPVTAKEEVAVKKPAESSNIWHDTTKQLTPAA 210 E + E + + +P E K ++ Sbjct: 1180 EQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATT 1239 Query: 211 KVEVPVTLKQLDKTITDQIEQL 232 T+ D T T+ L Sbjct: 1240 SSNDRSTVALCDLTSTNTNAVL 1261
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 44.9 bits (106), Expect = 4e-07 Identities = 16/36 (44%), Positives = 25/36 (69%) Query: 5 MYTAISGMNAFQQALSVTSNNIANANTTGYKKQSVV 40 + A+SG+NA Q AL+ SNNI++ N GY +Q+ + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI 39 Score = 38.4 bits (89), Expect = 4e-05 Identities = 12/47 (25%), Positives = 25/47 (53%) Query: 363 ISGSSLEGSNVDLSREFVNLMTYQSGFQGNTKVIRVADDVMKQIVNL 409 +S S V+L E+ NL +Q + N +V++ A+ + ++N+ Sbjct: 499 LSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 51.4 bits (123), Expect = 4e-12 Identities = 22/68 (32%), Positives = 37/68 (54%) Query: 7 IPLRIDFELGRTKQPVGSLLDVKKGTVFRLEDSTANVVKITISGKCIGYGEILTKDGKMF 66 IP+++ ELGRT+ + LL + +G+V L+ + I I+G I GE++ K Sbjct: 60 IPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYG 119 Query: 67 VKITKLGE 74 V+IT + Sbjct: 120 VRITDIIT 127
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 145 bits (368), Expect = 4e-43 Identities = 81/334 (24%), Positives = 166/334 (49%), Gaps = 9/334 (2%) Query: 1 MSDKLSQEQIDALLSQMSEGKV-VDESTEIGDFGRFHPYDFHKPEKFGAEHLESLKTIAS 59 M++ LSQ++ID LL+ +S G ++++ I D + YDF +P+KF E + +L + Sbjct: 1 MTEVLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHE 60 Query: 60 AFTKKSMEFVSQRIRIPIHTEATLADQVSFASGYIETMPNDSYIFCIIDLGNPELGQIII 119 F + + +S ++R +H DQ+++ +I ++P S +I + +P G ++ Sbjct: 61 TFARLTTTSLSAQLRSMVHVHVASVDQLTYEE-FIRSIPTPS-TLAVITM-DPLKGNAVL 117 Query: 120 ELDLAYIIYIHECLSGGNPKRKLSERRLLSVFEELTLKSILEKFCEALKDSFKSVHPISP 179 E+D + I + L GG + +R L+ E ++ ++ + +++S+ V + P Sbjct: 118 EVDPSITFSIIDRLFGGT-GQAAKVQRDLTDIENSVMEGVIVRILANVRESWTQVIDLRP 176 Query: 180 EIVNIETNPALLRVTSPNDMMALVSVDIKSEFWISTMRIGVPFFSVEEIMNKLEN---VV 236 + IETNP ++ P++M+ LV+++ K M +P+ ++E I++KL + Sbjct: 177 RLGQIETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFS 236 Query: 237 EYTFDKRRNFDAEVEQELHQVEKEARIRVGEIKTTWKELNKLEVGDVL-LTETHIRDTLK 295 + + +L V+ + VG ++ + +++ L VGD++ L +TH+ D Sbjct: 237 SVRRSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFV 296 Query: 296 GYVTEKWKFECYMGKSGNQKAVKFMRHTGRTEQE 329 + + KF C G G + A + + T QE Sbjct: 297 LSIGNRKKFLCQPGVVGKKIAAQILERIESTSQE 330
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 51.4 bits (123), Expect = 4e-10 Identities = 21/71 (29%), Positives = 42/71 (59%) Query: 444 ILEDIPVTLEVVFGTAKVKLEKFISWCEKDVIILKESMNEPLVLALNGVTIGKGILVRVD 503 ++ DIPV L V G ++ +++ + + V+ L EPL + +NG I +G +V V Sbjct: 56 LIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVA 115 Query: 504 DHFGIQMTELV 514 D +G+++T+++ Sbjct: 116 DKYGVRITDII 126
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 135 bits (340), Expect = 2e-36 Identities = 112/556 (20%), Positives = 215/556 (38%), Gaps = 66/556 (11%) Query: 4 SDFNTSLSGMSAAQIANMVAQQNISNMNTPGYIRQAVDQTAVYGDGGLLGGKQTGYGVKV 63 S N ++SG++AAQ A A NIS+ N GY RQ + L G G GV V Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTT--IMAQANSTLGAGGWVGNGVYV 59 Query: 64 TDIKRLTNTALTTQYNNQIAKQSASLYQSGALNQALNLFGTPGKNTPSDNLDNFFTAWAA 123 + ++R + +T Q + S + +++ N+ T + + + +FFT+ Sbjct: 60 SGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLAT-QMQDFFTSLQT 118 Query: 124 LAKNPDQATNTTALLSSMSIFTDQLNQLHSGLKELETTIAADTDAAIQDLNSLIKKLGSI 183 L N + AL+ +Q L++ + + A++ +N+ K++ S+ Sbjct: 119 LVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASL 178 Query: 184 NKAI----GNAGSNPPNDLLNQRDQLLSTMAGYAGISVSAHPNNPDVYDVTIG-GRLVVQ 238 N I G PN+LL+QRDQL+S + G+ VS Y++T+ G +VQ Sbjct: 179 NDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDG--GTYNITMANGYSLVQ 236 Query: 239 GDETTEITS-------TRTATGFEFSVDGQKLNMPE-----GSIIASVRVNQNEIKSYQE 286 G ++ + +RT + + +PE GS+ + ++ + Sbjct: 237 GSTARQLAAVPSSADPSRTTVAY-VDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRN 295 Query: 287 KIETFSNGLAKALDDIQV------KNVNKTMDDLQK------------------INDALQ 322 + + A+A + + + + K + DA Sbjct: 296 TLGQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASA 355 Query: 323 ANPNDEKLLSNRDELLRQLEKFPGVTRSGDTLTIGGVDHPVDTLGTSTYVTDVNDFSIPI 382 D K+ + ++ Q+ + T T G T T VND S + Sbjct: 356 VLATDYKISFDNNQW--QVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVND-SFTL 412 Query: 383 FAQSSGKWILNPAIT-------------SNADNKPFLGVIAADIASLKTDKNIQGTTFPS 429 S ++ IT ++DN+ ++ S +F Sbjct: 413 KPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGA---KSFND 469 Query: 430 FMDGIITEVATDASKSSATATADTQALSSLTESKSSLEGVNIDEEMTNIMQYQSYYVANT 489 +++++ + ++ ++ L+ + S+ GVN+DEE N+ ++Q YY+AN Sbjct: 470 AYASLVSDIGNKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANA 529 Query: 490 KAMNTVNDMMKALLAM 505 + + T N + AL+ + Sbjct: 530 QVLQTANAIFDALINI 545
>FLAGELLIN#Flagellin signature. Length = 507 Score = 45.4 bits (107), Expect = 1e-07 Identities = 37/238 (15%), Positives = 75/238 (31%), Gaps = 1/238 (0%) Query: 1 MRISTNQQASSIINQLNNVSGNLAKYQLQVSSGKKYESMSENPGATAQILSYNHVLSQLN 60 I+TN + N LN +L+ ++SSG + S ++ A + + L Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLT 61 Query: 61 REKTDVTEAKSLLNTAETSLSSMSTSMNRVNALVLQAINGTSDKDNMSQSAEEIKGLLDV 120 + + + S+ T E +L+ ++ ++ RV L +QA NGT+ ++ +EI+ L+ Sbjct: 62 QASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEE 121 Query: 121 LISVANSED-DGRYVFSGSSTSVKPFTTDKTTGEIIYNGTTENKKFRVTDTLEVEVFHDG 179 + V+N +G V S + + I + K + Sbjct: 122 IDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEAT 181 Query: 180 SAMTDVFNNIQKIVDAMKTGDKDALSALQETNSKNIEIITNSMTNIGGQKNGVTAYDN 237 D G + + + Sbjct: 182 VGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 32.6 bits (74), Expect = 3e-04 Identities = 27/120 (22%), Positives = 49/120 (40%), Gaps = 14/120 (11%) Query: 4 GINTSGSALNAAKQWMEVSSNNIANADSSAAPGETPFLRKRVVLSEITPFETALTGTKGV 63 IN + S LNAA+ + +SNNI++ + + + R+ ++++ A G G Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAG------YTRQTTIMAQANSTLGA-GGWVGN 55 Query: 64 KVSEISSDTGSVKRVYDPTHPNANEAGYVNYANVDMTAEMTNLMVGQKMYAANTSALQAN 123 V V+R YD N+ + +TA + M + +TS+L Sbjct: 56 GV-----YVSGVQREYDAFI--TNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQ 108 Score = 28.4 bits (63), Expect = 0.008 Identities = 18/72 (25%), Positives = 30/72 (41%), Gaps = 4/72 (5%) Query: 65 VSEISSDTGSVKRVYDPTHPNANEAGY---VNYANVDMTAEMTNLMVGQKMYAANTSALQ 121 VS+I + T ++K T N + + V++ E NL Q+ Y AN LQ Sbjct: 475 VSDIGNKTATLKTSSA-TQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQ 533 Query: 122 ANEKMMEKDLEI 133 + + + I Sbjct: 534 TANAIFDALINI 545
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 31.2 bits (70), Expect = 2e-04 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Query: 35 QMLDSMSDTQSNAQTSVSNLLTTGEG-NASDVLIQMKKAESEMKTAAVIRDNVIESYKQL 93 LD +SDTQ+ A+T G +DV+ M+KA M+ +R+ ++ +Y+++ Sbjct: 39 AALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEV 98 Query: 94 LNMQV 98 ++MQV Sbjct: 99 MSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 171 bits (435), Expect = 7e-49 Identities = 110/584 (18%), Positives = 219/584 (37%), Gaps = 83/584 (14%) Query: 9 SKLKNWHKGAILVGLFVVVTVLL---LYMNTPKTEVTLYKNLSETSQQQVTDQLAKMGVD 65 ++L+ + ++V V +++ L+ TP TL+ NLS+ + QL +M + Sbjct: 17 NRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYR-TLFSNLSDQDGGAIVAQLTQMNIP 75 Query: 66 YTVDK-SGNILVDEKVETLVRDKFADLGIPYTGQDGNDILLNSSLGASEEDKKMQEKVGT 124 Y SG I V +R + A G+P G G ++L G S+ +++ + Sbjct: 76 YRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFSEQVNYQRAL 135 Query: 125 KVNLEKEIVQSYGTTIDSASVQLTLPESSSIFEEASQKGTAAVTLKTKNNQTLTSEQVLG 184 + L + I + SA V L +P+ S F + +A+VT+ + + L Q+ Sbjct: 136 EGELARTIETLGP--VKSARVHLAMPKPSL-FVREQKSPSASVTVTLEPGRALDEGQISA 192 Query: 185 IQRTVSAAVPNVASDDVAIIDTKNGVISEADTSKEEGSSAYKNEVDIQNAIGKNVKTDIE 244 + VS+AV + +V ++D ++++++TS + + A ++ N + ++ IE Sbjct: 193 VVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDA---QLKFANDVESRIQRRIE 249 Query: 245 GTLSSIFALDNFRVNTNVAVNFDEIKQNTEHY-PNDGKVRSNQKDTSTDTSKGSANTTES 303 LS I N ++F +Q EHY PN ++ + + S+ Sbjct: 250 AILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPG 309 Query: 304 ---GTASN--------------------ADVPNYTEQNGDDTNTYTSEKSSETTNYELDS 340 G SN + P + ++ S + +ET+NYE+D Sbjct: 310 GVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDR 369 Query: 341 TIQEIKKHPA-LAKTNVVVWVDQNALNK------NGVDMAEFTKAIGVSAGLTPNMTTEE 393 TI+ K + + + +V V V+ L M + + G + Sbjct: 370 TIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMGFSDK----- 424 Query: 394 AGADGEAAAAPTFEGTFQNGD-VTIMPIQFLDNATPAEKDTTEKAEPASKAWIWW----L 448 GD + ++ F + D T P + + Sbjct: 425 ------------------RGDTLNVVNSPF------SAVDNTGGELPFWQQQSFIDQLLA 460 Query: 449 AGGLLFAVIAAGIITYIILLKRKEQLEEALEPEEKDYIPAEEAIINPEEHPDFNFQTDAF 508 AG L ++ A I+ + + + E + ++ + + E + Sbjct: 461 AGRWLLVLVVAWILWRKAVRPQLTRRVEEAKAAQE-----QAQVRQETEEAVEVRLSKDE 515 Query: 509 DLSE--PELKARKESLKNKLGEMAKEDPGRAAAVIQKWLNERQE 550 L + + E + ++ EM+ DP A VI++W++ E Sbjct: 516 QLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWMSNDHE 559
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 193 bits (491), Expect = 8e-61 Identities = 112/335 (33%), Positives = 189/335 (56%), Gaps = 4/335 (1%) Query: 34 SGISRREKAALIIWSLDEQIATEVVDLLPDASKQRLAREMAKMKEMDGGAVEEATREFLG 93 S ++ ++KAA+++ S+ +I+++V L + L E+AK++ + + EF Sbjct: 13 SALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFK- 71 Query: 94 ELELLSGGIAKLDREHLQRLFPDMTTEELNQLIYGVEAESRIGETALDILREIDDVDSLF 153 EL + I K ++ + L + I S + + +R D ++ Sbjct: 72 ELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIIN-NLGSALQSRPFEFVRRADPA-NIL 129 Query: 154 TIISDESPQTIAMIASYMKPEEASKLLALLPEEKMINTVIGIASLEQFDSEVMQNVSNLL 213 I E PQTIA+I SY+ P++AS +L+ LP E N IA +++ EV++ V +L Sbjct: 130 NFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVL 189 Query: 214 RIKLDTMSNSSLNKTDGIKNVANILNNVTRGLERTIFEHLDAEQAELSERIKEKMFMFED 273 KL ++S+ G+ NV I+N R E+ I E L+ E EL+E IK+KMF+FED Sbjct: 190 EKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFED 249 Query: 274 IILLDNMTLQQVLAEIQDNNKIARALKNEKEELKEKILSCVSKNRRDMITEELEVLGPIR 333 I+LLD+ ++Q+VL EI D ++A+ALK+ ++EKI +SK M+ E++E LGP R Sbjct: 250 IVLLDDRSIQRVLREI-DGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTR 308 Query: 334 LSDVEQAQQDIANVVKNLEKDGKIVIQRGEQDVLI 368 DVE++QQ I ++++ LE+ G+IVI RG ++ ++ Sbjct: 309 RKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.0 bits (72), Expect = 0.002 Identities = 15/79 (18%), Positives = 33/79 (41%) Query: 24 YLDDIEETEEIESPYSKELEQLESHQKELEKHLSAIEIEQQKLANEKAALQAERQAIEEL 83 I+ E ++ +LE + +A + + L EKAAL+AE+ +E Sbjct: 244 DSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQ 303 Query: 84 RRDAEAEIEANKQAFEKEK 102 + A ++ ++ + + Sbjct: 304 SQVLNANRQSLRRDLDASR 322
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 30.0 bits (67), Expect = 0.011 Identities = 35/159 (22%), Positives = 57/159 (35%), Gaps = 41/159 (25%) Query: 99 ILGSSSGSIVAMHVLKNHPEVVKKIAFHEPPINTFLPDSE---MWQEANEKIVQTALTKN 155 IL SS S L+ + AF E P + FL D E W++ + V+ L Sbjct: 17 ILTSSFPSYTYAQDLQIASNYITDRAFIERPED-FLKDKENAIQWEKKEAERVEKNLDTL 75 Query: 156 MAEAMQLFGETLHIAPIDAESMSKPAVT--------IDEVTKDSTTQQM----------- 196 EA++L+ + D+E +S + T I+ ++ + + Sbjct: 76 EKEALELYKK-------DSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDK 128 Query: 197 -----------KYWFTYEIRQYTSSNISLDDFKPYVHQI 224 K+ F EIR + ISL+ F I Sbjct: 129 PINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETI 167
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 27.8 bits (62), Expect = 0.031 Identities = 14/52 (26%), Positives = 21/52 (40%), Gaps = 11/52 (21%) Query: 63 EASKKMTNPAPHKIYNTQVWIKNDRAVAIMQATIQTRTIINGVEMELNSDAK 114 E + AP+++YN I N V +M I +E L +AK Sbjct: 244 ETGTPAASIAPYRVYN----IGNSSPVELM-------DYIQALEDALGIEAK 284
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 64.4 bits (156), Expect = 2e-13 Identities = 80/314 (25%), Positives = 127/314 (40%), Gaps = 21/314 (6%) Query: 65 KVKYVMQENVEEKLLTGIAGGELPDIIMWDRYQTALYAPKGVLEPLDKLVKEDNLKMDDF 124 KV + +EEK A G+ PDII W + YA G+L + D D Sbjct: 60 KVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAE----ITPDKAFQDKL 115 Query: 125 YEESVKEMTYSDKLYGLPLLNDNRILFYNKKLLQEAGVKPPTTWDELATAAQKTTKWDGN 184 Y + + Y+ KL P+ + L YNK LL PP TW+E+ A K K G Sbjct: 116 YPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLP----NPPKTWEEIP-ALDKELKAKGK 170 Query: 185 KMTQAGMSLQDVGLFNLYLMQAGG------ELVTSDNKETAFNSEQGLEVLNYW-DKMQN 237 +LQ+ F L+ A G E D K+ ++ L + D ++N Sbjct: 171 SALM--FNLQE-PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKN 227 Query: 238 DLKVYQRGFDDGSDAFAAGKEAMTYNGPWALADYNKVEDLDYGVVEPPKGPNGDKGAIMG 297 + AF G+ AMT NGPWA ++ + ++YGV P +G Sbjct: 228 KHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDT-SKVNYGVTVLPTFKGQPSKPFVG 286 Query: 298 GFGLVMPKQAEHKDGAWDFMKWWTTKPENGVEFAKISGWLPANKIAAEDEYFTKDPNYSV 357 + + +K+ A +F++ + E G+E L A + + +E KDP + Sbjct: 287 VLSAGINAASPNKELAKEFLENYLLTDE-GLEAVNKDKPLGAVALKSYEEELAKDPRIAA 345 Query: 358 FVNTMKYAKIRPTV 371 + + +I P + Sbjct: 346 TMENAQKGEIMPNI 359
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 28.6 bits (64), Expect = 0.033 Identities = 18/71 (25%), Positives = 30/71 (42%) Query: 152 KIAVSGATGGVGSLSSAILSKRGFSVVASSGKSDAKEFLEKFGVSEIVSREAFQPEKVRA 211 K V+GA G +G S L + G VV +D + K E++++ FQ K+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 212 LDKQLYAGAID 222 D++ Sbjct: 62 ADREGMTDLFA 72
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 24.4 bits (53), Expect = 0.043 Identities = 9/34 (26%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Query: 1 MKKKWLLLILSVIVLCAIIFGIKWLLYRDNLVEM 34 MK L+ V+++C + +L R +L E+ Sbjct: 1 MKLPRSSLVWCVLIVCLTLLIFTYLT-RKSLCEI 33
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.3 bits (84), Expect = 3e-04 Identities = 17/80 (21%), Positives = 27/80 (33%), Gaps = 3/80 (3%) Query: 42 DKSVEEITSPVSGTIKEIKVAEGTVATVGQVLVTFDGVEGHEDDAEEESAAPKAESTEST 101 +EI + +KEI V EG G VL+ + +A+ Sbjct: 93 SGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGA---EADTLKTQSSLLQARLE 149 Query: 102 PAPAQASGKGIFEFKLPDIG 121 Q + I KLP++ Sbjct: 150 QTRYQILSRSIELNKLPELK 169 Score = 32.5 bits (74), Expect = 0.004 Identities = 11/36 (30%), Positives = 16/36 (44%) Query: 152 DKSVEEITSPVDGTVKDILVSEGTVATVGQVLVTFE 187 +EI + VK+I+V EG G VL+ Sbjct: 93 SGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLT 128 Score = 31.7 bits (72), Expect = 0.008 Identities = 10/34 (29%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Query: 152 DKSVEEITSPVDGTVKDILV-SEGTVATVGQVLV 184 + I +PV V+ + V +EG V T + L+ Sbjct: 324 RQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLM 357 Score = 31.7 bits (72), Expect = 0.009 Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 2/59 (3%) Query: 18 EIVKWFVQPGDKIEE-DESLFEVQNDKSVEEITSPVSGTIKEIKV-AEGTVATVGQVLV 74 EI+ Q D I L + + + I +PVS ++++KV EG V T + L+ Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLM 357
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 7e-23 Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 5/126 (3%) Query: 3 KILIAEDDSAILGVITAFLTEAGYQVMTAKNGIEAYHLFQKETFDLIIMDIMMPSMDGYT 62 IL+A+DD+AI V+ L+ AGY V N + DL++ D++MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 LTELIRST-STTPILMMTALSEEDDELKGFDLGADDYIQKPFSYLVLLKRVQVLLRRVNQ 121 L I+ P+L+M+A + +K + GA DY+ KPF L + ++ R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFD----LTELIGIIGRALA 120 Query: 122 SETKKQ 127 ++ Sbjct: 121 EPKRRP 126
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.0 bits (83), Expect = 0.001 Identities = 8/33 (24%), Positives = 19/33 (57%) Query: 1114 TIQAPFDGEVSSIYVSDGDTIESGDLLIEVNRI 1146 I+ + V I V +G+++ GD+L+++ + Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTAL 130 Score = 31.0 bits (70), Expect = 0.028 Identities = 13/35 (37%), Positives = 20/35 (57%) Query: 1083 TGSVIQVVVKKGDSVKKGDPLLITEAMKMETTIQA 1117 V +++VK+G+SV+KGD LL A+ E Sbjct: 104 NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 36.8 bits (85), Expect = 6e-05 Identities = 28/130 (21%), Positives = 45/130 (34%), Gaps = 9/130 (6%) Query: 50 PTKIVSLIPSNTEILFALGLGD-EVKGVSAYDDYPKEAQKIEKV----TSTSVDTEKIIA 104 P +IV+L E+L ALG+ V Y + E + V T + E + Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTE 94 Query: 105 LKPDLVLGHESMLATEKDAYKILTDAGINVFVVPDATN-LKEVEKSIATIGDLTGTEKEA 163 +KP ++ + + +I A F D L KS+ + DL + A Sbjct: 95 MKPSFMVWSAGYGPSPEMLARI---APGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAA 151 Query: 164 TKVTDSMEKQ 173 E Sbjct: 152 ETHLAQYEDF 161
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 70.9 bits (173), Expect = 2e-15 Identities = 57/228 (25%), Positives = 105/228 (46%), Gaps = 26/228 (11%) Query: 43 EVAREEMPPESEEPVFSLEQNR-------DDAMAALVVPQTRNSFLRAASTPTFQQTFIN 95 ++ E+ PE P ++ + A++ LV ++ S P + F+ Sbjct: 97 QMTPEQPLPEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPRNYDD--SLPGDSKAFLA 154 Query: 96 SISTQAMDLCKKYNLYPSVMIAQAALESNWGRSELGKA---PNYNLFGIK--GSYNGKSV 150 +S A ++ + +++AQAALES WG+ ++ + P+YNLFG+K G++ G Sbjct: 155 QLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVT 214 Query: 151 TMKTWEYSDSKGWYQINANFAKYPSHKESLEDNAKKLRNGPSWDSSYYKGAWRENAKTYK 210 + T EY + + ++ A F Y S+ E+L D L P + + + + A+ + Sbjct: 215 EITTTEYENGEA-KKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQ 273 Query: 211 DATAWLQGRYATDNTYASKLNTLISSYNLTQYDTLYDTIKQQKNVSED 258 DA YATD YA KL +I Q ++ D + + +++ D Sbjct: 274 DAG------YATDPHYARKLTNMIQ-----QMKSISDKVSKTYSMNID 310
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 185 bits (471), Expect = 2e-58 Identities = 81/333 (24%), Positives = 138/333 (41%), Gaps = 28/333 (8%) Query: 1 MNLLVTGGAGFIGSNFVHHILNKHDDYKVVNLDLLT-YAGT---MSNLEDIKENPNHVFV 56 M LVTG AGFIG + +L VV +D L Y + LE + P F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQ--VVGIDNLNDYYDVSLKQARLE-LLAQPGFQFH 57 Query: 57 EGNICDYDLVKKLVTDHKIDTIVNFAAESHVDRSIINPGIFIETNVQGTLNLLNVAKELN 116 + ++ D + + L + + V S+ NP + ++N+ G LN+L + Sbjct: 58 KIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK 117 Query: 117 VAKYLQVSTDEVYGSLGETGYFTEETPIA-PNSPYSASKASADLLVRSYFETYGLNVNIT 175 + L S+ VYG L F+ + + P S Y+A+K + +L+ +Y YGL Sbjct: 118 IQHLLYASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 176 RCSNNYGPHHFPEKLIPLMITNGLDGENLPIYGDGKNIRDWLHVSDHCAAIDLVIHNGKS 235 R YGP P+ + L+G+++ +Y GK RD+ ++ D AI + Sbjct: 177 RFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPH 236 Query: 236 ------------------GEVYNVGGHNERTNNEIVHIIVDDLNLSKDKIVYVEDRLGHD 277 VYN+G + + + + D L + + K + + G Sbjct: 237 ADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI-EAKKNMLPLQPGDV 295 Query: 278 LRYAIDPKKIETELGWEPKYTFDTGIKETIEWY 310 L + D K + +G+ P+ T G+K + WY Sbjct: 296 LETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 63.6 bits (155), Expect = 9e-14 Identities = 53/244 (21%), Positives = 89/244 (36%), Gaps = 47/244 (19%) Query: 1 MSILVTGANGQLGTELVQLLKEHNLTVTEWD----------KDS--------------VD 36 M LVTGA G +G + + L E V D K + +D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 37 IVDKAAVKKAMLDLKPEWIIHCAAFTNVEAA-EDELKNVNWEVNVDGTENISEAAEIVGA 95 + D+ + E + V + E+ + N+ G NI E Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYA--DSNLTGFLNILEGCRHNKI 118 Query: 96 K-LVYISTDYVFDGTKKEAYLPDDKTN-PLNQYGIAKLAGEKVALEKNSQTYVIRTS--- 150 + L+Y S+ V+ +K + DD + P++ Y K A E +A S Y + + Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTY-SHLYGLPATGLR 177 Query: 151 --WVFGKYGN------NFVYSMLKLAETHKELKVVNDQLGRPTYTY--DLADFIRFVIEK 200 V+G +G F +ML+ K + V N + +TY D+A+ I + + Sbjct: 178 FFTVYGPWGRPDMALFKFTKAMLE----GKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDV 233 Query: 201 NPAY 204 P Sbjct: 234 IPHA 237
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.3 bits (91), Expect = 7e-05 Identities = 37/226 (16%), Positives = 75/226 (33%), Gaps = 16/226 (7%) Query: 505 HERQNENGNESTANRPTSTKQNRSAGTRAGEKMGDLMEAKNRMVDKAGDMKDTIKNAPTN 564 + + E N++ +T N A + + + + + T Sbjct: 981 YNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETV 1040 Query: 565 AKYAVHKGKRDLVRNVSEFSQSFADTRNLQQQERATKRNEKKATVAQRRQEMDKAKAEKS 624 A+ + + K + + ++ + K N + VAQ E + + ++ Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTET 1100 Query: 625 NLEPYASMQKRQRDYEERKQPVPRTAPTPAP-----QASTPKATPERTASTNQQHERPLQ 679 +++ + E+ Q VP+ +P + P+A P R + P Q Sbjct: 1101 KETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP-Q 1159 Query: 680 KQKNTTKEQVKANKR----------ENTSTTSKNSKTENKITKTTT 715 Q NTT + + K E+T+ + NS EN T Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPA 1205
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 49.8 bits (119), Expect = 4e-09 Identities = 32/148 (21%), Positives = 64/148 (43%), Gaps = 25/148 (16%) Query: 124 TLESLLERGI---------IPIVNENDTVAVEELEHVTKYGDNDLLSAIVAKLVQADLLI 174 T++ L+ERG+ +P++ E+ E++ V D DL +A+ V AD+ + Sbjct: 178 TIKKLVERGVIVIASGGGGVPVILEDG-----EIKGVEAVIDKDLAGEKLAEEVNADIFM 232 Query: 175 MLSDIDGFYGSNPSTDPDAVMFSEINQITPEIEALAGGKGSKFGTGGMLTKLSAAS-YCM 233 +L+D++G T + ++ E E + F G M K+ AA + Sbjct: 233 ILTDVNGAA-LYYGT-EKE---QWLREVKVE-ELRKYYEEGHFKAGSMGPKVLAAIRFIE 286 Query: 234 NANQKMILTNGKNPTIIFDIMQGEQIGT 261 ++ I+ + + ++G+ GT Sbjct: 287 WGGERAIIA---HLEKAVEALEGK-TGT 310
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.7 bits (74), Expect = 0.002 Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 175 ALESDLKPNSTLILLGSSGVGKSSFINSLAGTDLMKTAGIREDDSKGKHTTTHREMHLLS 234 +E K + +++L G+ G+GKS+ IN+L G D D GK + + Sbjct: 588 VMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHF--DIGTGKDSY----EQIAG 641 Query: 235 NGWIV 239 Sbjct: 642 I-VAY 645
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 26.8 bits (59), Expect = 0.038 Identities = 13/38 (34%), Positives = 21/38 (55%) Query: 52 KNKYEKLLAQQEVDKATEAEAKKKAEEDAKKKAEEAKK 89 + EKL AQQE D + + K ++ A +K++E K Sbjct: 391 RKAMEKLAAQQEEDAKNQGKGDCKQQQGASEKSKEGKV 428
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 33.7 bits (77), Expect = 8e-04 Identities = 22/114 (19%), Positives = 40/114 (35%), Gaps = 4/114 (3%) Query: 401 NVAVQQYLQEQNKKEATKITDNLISSGSADGYSYTYAASIALQD-KQIDKAETMAKEAIN 459 ++A QY + ++A K+ L D + Q Q D A Sbjct: 41 SLAFNQYQSGK-YEDAHKVFQALCVLDHYD-SRFFLGLGACRQAMGQYDLAIHSYSYGAI 98 Query: 460 IDKDIPEAHYYLSVCYRIKGDMPNAIKEANSARELSSN-PFFDSYYDELEKIKE 512 +D P ++ + C KG++ A A+EL ++ F + + E Sbjct: 99 MDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEFKELSTRVSSMLE 152
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.5 bits (79), Expect = 2e-05 Identities = 16/46 (34%), Positives = 27/46 (58%) Query: 1 MNKINGFSLVESMVSLLLFAMVCSFLLPTAMTIFEKLDHQKETSRV 46 +K GF+L+E MV +++ ++ S ++P M EK D QK S + Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDI 49
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 28.1 bits (62), Expect = 0.042 Identities = 14/44 (31%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Query: 68 DLKNTYTENQHLKERLE-ELAQLESEVADLKKENKDLKESLDIT 110 L+ ++ K+++E L + S++A L+K NK+L+ES +T Sbjct: 383 SLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLT 426
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 470 bits (1210), Expect = e-170 Identities = 192/338 (56%), Positives = 247/338 (73%), Gaps = 6/338 (1%) Query: 1 MFGFGNKDIGIDLGTANTLVYMKGKGIVLREPSVVAMKKD----TQEIVAVGSDAKNMIG 56 G + D+ IDLGTANTL+Y+KG+GIVL EPSVVA+++D + + AVG DAK M+G Sbjct: 5 FRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLG 64 Query: 57 RTPGNIVAIRPMKDGVIADYDTTAAMMKYYIQKA-GKSVNASKPRVMICVPSGITGVEKR 115 RTPGNI AIRPMKDGVIAD+ T M++++I++ S PRV++CVP G T VE+R Sbjct: 65 RTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERR 124 Query: 116 AVIDATRQAGAKDAFTIEEPFAAAIGAGLPVGEPTGSMVVDIGGGTTEVAVISLGGIVTS 175 A+ ++ + AGA++ F IEEP AAAIGAGLPV E TGSMVVDIGGGTTEVAVISL G+V S Sbjct: 125 AIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYS 184 Query: 176 RSVRTAGDDLDEVIINYIRKKYNLLIGDRTAEAIKMEIGSASPKGLDLSPFSIRGRDLVT 235 SVR GD DE IINY+R+ Y LIG+ TAE IK EIGSA P G ++ +RGR+L Sbjct: 185 SSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYP-GDEVREIEVRGRNLAE 243 Query: 236 GLPKTIEITPEEISEALADTVAAIIDAVKGTLENTPPELSADIMDKGIVLTGGGALLRNL 295 G+P+ + EI EAL + + I+ AV LE PPEL++DI ++G+VLTGGGALLRNL Sbjct: 244 GVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNL 303 Query: 296 DTVISEETKMPVIIADEPLDCVAIGTGKALENMDMYKR 333 D ++ EET +PV++A++PL CVA G GKALE +DM+ Sbjct: 304 DRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGG 341
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 94.1 bits (234), Expect = 3e-25 Identities = 48/206 (23%), Positives = 98/206 (47%), Gaps = 14/206 (6%) Query: 35 SECNYCQKKLAFYHIIPIFSFLFFRGKSRCCERPIPIIYFLMELVTPIYILLLYIQFSFS 94 S C +C + IP+ S+L+ RG+ R C+ PI Y L+EL+T + + + + + Sbjct: 72 SCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAVAMTLAPG 131 Query: 95 YSFLLYYIIYYFLAFFFITDIFYLYVPNSILIVFFCVLATIAILYNQ-----SLMDLIYS 149 + L ++ + L D+ + +P+ + L +L+N SL D + Sbjct: 132 WGTLAALLLTWVLVALTFIDLDKMLLPDQLT----LPLLWGGLLFNLLGGFVSLGDAVIG 187 Query: 150 G----GISCLFYLLFFIIFRK-GIGLGDIKILIILSTFLGFKIGYYIFFLAIIMGTIILL 204 + Y F ++ K G+G GD K+L L +LG++ + L+ ++G + + Sbjct: 188 AMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGI 247 Query: 205 TALMLKKVKKNKQVPFVPYIFVSFLL 230 ++L+ ++K +PF PY+ ++ + Sbjct: 248 GLILLRNHHQSKPIPFGPYLAIAGWI 273
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 52.0 bits (124), Expect = 1e-08 Identities = 33/262 (12%), Positives = 87/262 (33%), Gaps = 3/262 (1%) Query: 676 KHELGQLAEKIAELNESTREMESAVQLAKDSMAKKREELEETRVIGENLRLQEKELLGKL 735 EL + + E +A ++ ++ L + +L + + Sbjct: 115 IQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARK---ADLEKALEGAMNFS 171 Query: 736 DRETENLERFNKQLQLYDIEKADGSEELNKLLERKETLLQEQVEIAKQIEVTDEEIKAMT 795 ++ ++ + + +A+ + L + + + + + Sbjct: 172 TADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLE 231 Query: 796 SSSKALESKRAADLESLSSLKAQIAAKREQLQSATEAVERVTTTLHENYEQKEAAEQKLA 855 + + + AD + +L+A+ AA + +A+E + + + E + A Sbjct: 232 KALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKA 291 Query: 856 SLKTNLTSVHTSEETARKSIEELRKDKTETSEKLTQTRQTRAELQEKLELLEAELTQKNN 915 +L+ + + + + LR+D + E Q +L+E+ ++ EA Sbjct: 292 ALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRR 351 Query: 916 QISFYMEQKNNAEISIGRLEVD 937 + E K E +LE Sbjct: 352 DLDASREAKKQLEAEHQKLEEQ 373 Score = 48.5 bits (115), Expect = 1e-07 Identities = 42/248 (16%), Positives = 98/248 (39%), Gaps = 10/248 (4%) Query: 669 KSSILTRKHELGQLAEKIAELNESTREMESAVQLAKDSMAKKREELEETRVIGENLRLQE 728 K+++ R+ EL + E + + ++ K ++A ++ +LE+ N + Sbjct: 185 KAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTAD 244 Query: 729 KELLGKLDRETENLERFNKQLQLYDIEKADGSEELNKLLERKETLLQEQVEIAKQIEVTD 788 + L+ E LE +L+ + +TL E+ + + + Sbjct: 245 SAKIKTLEAEKAALEARQAELEK---ALEGAMNFSTADSAKIKTLEAEKAALEAEKADLE 301 Query: 789 EEIKAMTSSSKALESKRAADLESLSSLKAQIAAKREQLQSATEAVERVTTTLHENYEQKE 848 + + + ++ ++L A E+ L+A+ EQ + + + + + L + E K+ Sbjct: 302 HQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKK 361 Query: 849 AAEQKLASLKTNLTSVHTSE-------ETARKSIEELRKDKTETSEKLTQTRQTRAELQE 901 E + L+ S + +R++ +++ K E + KL + EL+E Sbjct: 362 QLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEE 421 Query: 902 KLELLEAE 909 +L E E Sbjct: 422 SKKLTEKE 429 Score = 37.7 bits (87), Expect = 3e-04 Identities = 26/225 (11%), Positives = 60/225 (26%) Query: 145 KIDEILNSKPEERRSIFEEAAGVLKYKHRKKQAENKLFETEENLNRVQDILYELEGQLEP 204 ++ + + + + G + + L + L Q L + Sbjct: 145 TLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN 204 Query: 205 LEMQASIAKDYLFQQEELEKYEVTLLASEISSLTEKLAEVRKEFGENQTVLIKLREELHA 264 S L ++ L + + + L Sbjct: 205 FSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAE 264 Query: 265 EEAVISREKQALNETDIALDKLQERLLVETEKLEQLEGERNLQLERKKHSSENEQVYAET 324 E + + L+ + LE + + ++ + E Sbjct: 265 LEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREA 324 Query: 325 LAVITEKITALEEQKEVLSSSKLEKETALEIAIKSKKVLEATLAK 369 + + LEEQ ++ +S+ L+ + ++KK LEA K Sbjct: 325 KKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQK 369 Score = 37.0 bits (85), Expect = 5e-04 Identities = 42/285 (14%), Positives = 86/285 (30%), Gaps = 17/285 (5%) Query: 760 SEELNKLLERKETLLQEQVEIAKQIEVTDEEIKAMTSSSKALESKRAADLESLSSLKAQI 819 E +K TL + +++ + + +T + K L ++ Sbjct: 56 QERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEK----LRKNDKSLSEK 111 Query: 820 AAKREQLQSATEAVERVTTTLHENYEQKEAAEQKLASLKTNLTSVHTSEETARKSIEELR 879 A+K ++L++ +E+ A + L + K L + E A + Sbjct: 112 ASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFS 171 Query: 880 KDKTETSEKLTQTRQTRAELQEKLELLEAELTQKNNQISFYMEQKNNAEISIGRLEVDIA 939 + + L+ + LEA + + M I LE + A Sbjct: 172 TADSAKIK----------TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKA 221 Query: 940 NRIDRLQEAYLLTPEQAEEKILSEVNTEQARSKVRLLKRSIDELGIVNIGAIEEFERIQE 999 R + + ++ L+ EL GA+ Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 1000 RFDFLTGQQADL---LAAKETLFKVMDEMDEEMKIRFSESFEAIK 1041 + L ++A L A E +V++ + ++ S EA K Sbjct: 282 KIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKK 326 Score = 32.7 bits (74), Expect = 0.008 Identities = 46/236 (19%), Positives = 90/236 (38%), Gaps = 14/236 (5%) Query: 678 ELGQLAEKIAELNESTREMESAVQLAKDSMAKKREELEETRVIGENLRLQEKELLGKLDR 737 ++ L + A L E+E A++ A + +++ L ++ +L + Sbjct: 247 KIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQV 306 Query: 738 ETENLERFNKQLQLYDIEKADGSEELNKLLERKETLLQEQVEIAKQIEVTDEEIKAMTSS 797 N + + L K E KL E+ + + + + ++ + E K + + Sbjct: 307 LNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAE 366 Query: 798 SKALESKRAADLESLSSLKAQIAAKREQLQSATEAVERVTTTLHENYEQKEAAEQKLASL 857 + LE + S SL+ + A RE A + VE+ E A KLA+L Sbjct: 367 HQKLEEQNKISEASRQSLRRDLDASRE----AKKQVEK----------ALEEANSKLAAL 412 Query: 858 KTNLTSVHTSEETARKSIEELRKDKTETSEKLTQTRQTRAELQEKLELLEAELTQK 913 + + S++ K EL+ ++ L + +AE KL +A +Q Sbjct: 413 EKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQT 468
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 708 bits (1830), Expect = 0.0 Identities = 226/572 (39%), Positives = 346/572 (60%), Gaps = 11/572 (1%) Query: 1 MAFDAMFLKAMTEELAEHGESGRIMKIHQPFSHELVLYIRKNRENKRLLISSHPSYARIQ 60 MA D +FL ++ +EL +G+I K++QP E++L IRK R + +LLISS +Y RI Sbjct: 1 MALDGIFLYSIIDELKNTIINGKIDKVNQPEKDEIILNIRKGRLSFKLLISSSSNYPRIH 60 Query: 61 WTDDIPENPATPPMFCMLLRKYLEGAIIESITQLPNERILQFSIRGKDDIGENRFCDLFV 120 TD NP PMFCM+LRKY+ A I I Q+ +RI+ D++G N L + Sbjct: 61 LTDLTKPNPIKAPMFCMVLRKYISNAKIVDIHQINQDRIVVIDFESTDELGFNSIYSLII 120 Query: 121 EIMGRHSNITLVDRAKNVIVDCIKHVSPAQNSYRTLLPGATYVLPPATDKLNPFEVTSEQ 180 EIMGRHSN+TL+ + N+I+D IKH++P N+YR++ PG YV PP + KLNPF+ + + Sbjct: 121 EIMGRHSNMTLIRKRDNIIMDSIKHITPDINTYRSIYPGIEYVYPPKSPKLNPFDFSYDM 180 Query: 181 ILDRLDFSAGRIDKQ-LVQNFAGFSPLLAREIVFRAGNLTADSLVAAFFEVMGLVND--- 236 I + ++ +++ + F G S L+ EI FR N + D ++ E++ + D Sbjct: 181 IENFTKENSLQLNDNIFSKIFTGVSKTLSSEICFRLKNNSIDLSLSNLKEIVEVCKDLFK 240 Query: 237 HLGSAAVPNEWRIQNKEDYYFFSLRHV---DAEITEFANLSTLLDHFYIGKARRDRVHQF 293 + S +N F+ L + D + ++ + S LL++FY K + DR+ Sbjct: 241 EIQSNKFEFNCYTKNNSFVGFYCLNLMSKEDYKKIQYDSSSKLLENFYYAKDKSDRLKSK 300 Query: 294 AHDLEKLLSNELARSRLKIEKLENTLLETEKADVYRIQGELLTANLHLMERGMEEITVEN 353 + DL+K++ N + R K + L NTL + E D++++ GELLTAN++ +++G+ I + N Sbjct: 301 SSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTANIYALKKGLSHIELAN 360 Query: 354 FYDD-MKKMTIPLDTRKTPSANAQSYFSRYQKLRNAVEVVKEQIALTKEEITYLESVESQ 412 +Y + + I LD KTPS N QSY+ +Y KL+ + E EQ+ +EE+ YL SV + Sbjct: 361 YYSENYDTVKITLDENKTPSQNVQSYYKKYNKLKKSEEAANEQLLQNEEELNYLYSVLTN 420 Query: 413 LETSGPQD-VEEIRQELAEQGYLRYKQKKGSRKKATLPAPEKYTSSTGLTILVGKNNKQN 471 + + D +EEI++EL E GY+++K+ S+K T P + S G+ I VGKNN QN Sbjct: 421 INNADNYDEIEEIKKELIETGYIKFKKIYKSKKSKTSK-PMHFISKDGIDIYVGKNNIQN 479 Query: 472 DYLTNKLARNNEYWFHVKDLPGSHVVIQSN-NPDETSITEAAMIAAYYSKARLSATVPVD 530 DYLT K A ++ WFH K++PGSHV++++ + E+++ EAA +AAYYSK++ S+ VPVD Sbjct: 480 DYLTLKFANKHDIWFHTKNIPGSHVIVKNIMDIPESTLLEAANLAAYYSKSQNSSNVPVD 539 Query: 531 GTLVKHVKKPNGAKPGYVIYDNQTTYFVTPDE 562 T VK+VKKPNGAKPG VIY T +VTP Sbjct: 540 YTEVKNVKKPNGAKPGMVIYSTNQTIYVTPTN 571
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 31.2 bits (70), Expect = 0.029 Identities = 18/72 (25%), Positives = 30/72 (41%), Gaps = 21/72 (29%) Query: 977 ASIPVSQVKKIGENQETLIDY----------------IRNGQVTLVVNTLTTGKRPERDG 1020 S+P+S+ KIG NQ+ + DY +G + N +T Sbjct: 1069 GSVPLSEYDKIGFNQKNMKDYSDSFKFSTKLNNAVKDTNSGFTQFLTNAFSTASY----- 1123 Query: 1021 FQIRRESVENGI 1032 + + RE+ E+GI Sbjct: 1124 YCLARENAEHGI 1135
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 35.9 bits (83), Expect = 3e-04 Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 8/61 (13%) Query: 4 LKNGQVLNASGKLESKDVLIQNGKVNLIADSIEVTSGEEFDATGKLITPGFIDVHVHLRE 63 LK+G++ A GK + D +Q G ++ EV +GE GK++T G +D H+H Sbjct: 90 LKDGRIA-AIGKAGNPD--MQPGVTIIVGPGTEVIAGE-----GKIVTAGGMDSHIHFIC 141 Query: 64 P 64 P Sbjct: 142 P 142
>PF06872#EspG protein Length = 398 Score = 30.5 bits (68), Expect = 0.018 Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Query: 466 LDLFVTDGAQNRMSYS--NKDYDKILNDASVTYAADDQKRWDEMVKAEKILLTDDVAI-Q 522 + +FV D + + N + ++ DA++ +D +K W+EM AEK+L + + Sbjct: 5 IKIFVIDETERAFMLNGLNNNSASLVLDATIKINSDYKKPWNEMTCAEKLLKILTLGLWN 64 Query: 523 PLYQRS 528 P Y + Sbjct: 65 PKYSQD 70
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.0 bits (72), Expect = 0.014 Identities = 35/272 (12%), Positives = 80/272 (29%), Gaps = 19/272 (6%) Query: 482 VFLEQKKIRQEWQQLLNEMDIIASQIAELRATENKLNETIYQHTMELKQLFSDLG----- 536 +E ++ + L + EL + E + ++ L + S + Sbjct: 62 FEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEAR 121 Query: 537 IKHNPDANWAYELAVYKKNSEKAQLAMELISKLEPLAEKQEVYKARLANLELPGKYTDTE 596 A +++ L E K A K ++ KA + + Sbjct: 122 KADLEKALEGAMNFSTADSAKIKTLEAE---KAALAARKADLEKALEGAMNFSTADSAKI 178 Query: 597 EKITFLRQGLLYYRNHLTENAKLAEKLEQVTMQLDLVKQDLLLIKKEKADLLASANAKNE 656 + + + L + L + + A + + L A Sbjct: 179 KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAM 238 Query: 657 EEFRMAAIRVKEEQNWRERLVLIEAQLEPEKRIALNQYEN-----------QATIKEKEL 705 + ++K + + L +A+LE A+N +A ++ ++ Sbjct: 239 NFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKA 298 Query: 706 QLEETLRQIELEQEKIHASLAAQNHAIHKLEE 737 LE + + ++ + L A A +LE Sbjct: 299 DLEHQSQVLNANRQSLRRDLDASREAKKQLEA 330
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 28.5 bits (63), Expect = 0.033 Identities = 33/261 (12%), Positives = 76/261 (29%), Gaps = 1/261 (0%) Query: 3 TEEKYKIFAKTYVMNGFNGKEAAISAGYSTKTAEQQASRLLRNVKVLELIDEEMKLLSKR 62 T E + ++ +E A T + + S L N K L+ ++E+ Sbjct: 37 TNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSN 96 Query: 63 MQDDASKIYAELWKQVRMIDDKMAKHEEASRKLSITDARKITAIADINNLKAKIRRTESK 122 ++ K L ++ I + A+ + + L A I L+A+ ++ Sbjct: 97 AKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAAR 156 Query: 123 IKKMDGRKADEGKFKKELLEEYDELKIQLEELEDSVSEIYEENSTSKRDLLWHKDWKEIL 182 ++ F + L+ + LE +E+ + + + L Sbjct: 157 KADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTL 216 Query: 183 SLRAQILQDLFDRSGYKETKDMQDRRVALLDAQINKLELEAKKDCKDSGFATIIMSNVDE 242 L K + + A +A + + + + ++ Sbjct: 217 EAEKAALAARKADLE-KALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNF 275 Query: 243 MQAYLDKKAGGTDERDDTQTT 263 A K E+ + Sbjct: 276 STADSAKIKTLEAEKAALEAE 296
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 27.4 bits (61), Expect = 0.015 Identities = 14/43 (32%), Positives = 19/43 (44%), Gaps = 1/43 (2%) Query: 63 VLQESFRKNGKLYRAIKYKADFLVRYSDGHEELIDIKGMLTKE 105 VL + +L R I Y+ LV YS E+ + GM E Sbjct: 76 VLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLA-DGMTVGE 117
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 38.6 bits (90), Expect = 8e-06 Identities = 34/163 (20%), Positives = 60/163 (36%), Gaps = 31/163 (19%) Query: 1 MNVLVIGANGKIGRLLVEKLAMEKGFFVRA---------MVRKAEQVSELEKLGAKPIIA 51 M LV GA G IG + ++L +E G V + K ++ L + G + Sbjct: 1 MKYLVTGAAGFIGFHVSKRL-LEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 52 DLK-KDF---HYAYDEIEAVIFTAGSGGHTPASE----TVNIDQNGAIKAIETAKEKGVR 103 DL ++ +A E V + + E + + G + +E + ++ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 104 RFIIVSS---YGA--------DNPENGPESLAHYLKAKQAADE 135 + SS YG D+ + P SL Y K+A + Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSL--YAATKKANEL 160
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.0 bits (75), Expect = 2e-04 Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 79 KEHQGKGYGGDALEQIIEMVKNLPEQPARLRLSYEPDNIVAEKFYAKYGF 128 K+++ KG G L + IE K L L + NI A FYAK+ F Sbjct: 99 KDYRKKGVGTALLHKAIEWAKE--NHFCGLMLETQDINISACHFYAKHHF 146
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 56.8 bits (137), Expect = 3e-10 Identities = 58/297 (19%), Positives = 117/297 (39%), Gaps = 39/297 (13%) Query: 227 SLLIGTVLLVLVFLLVIYRSPILALIPLIAVGFAYLVITPILGLLAKEGIITYGSQGLSI 286 +L +L+ LV + + ++ LIP IAV +V+ +LA G ++ Sbjct: 343 TLFEAIMLVFLV-MYLFLQNMRATLIPTIAVP---VVLLGTFAILAAFGY------SINT 392 Query: 287 MT----VLLFGAGTDYCLFLISRFRSHLHTEK-NRFQAFKEAFSGTAGAIALSGLTVMAA 341 +T VL G D + ++ + +K +A +++ S GA+ + + A Sbjct: 393 LTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAV 452 Query: 342 LL--LLLAAEYGS-FHNFAVPFSLAIFIMMISSLTLVPALLGIFGRVSFWPFVPRTVEME 398 + G+ + F++ A+ + ++ +L L PAL + P + E Sbjct: 453 FIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLK-------PVSAEHH 505 Query: 399 ETRAKKKGKTPK--HHKENRFWHKIGEMSAKHPVRILIITLIILIGCGIFTTQVKYTYDT 456 E + G H N + + +G++ R L+I +I+ G + ++ ++ Sbjct: 506 ENKGGFFGWFNTTFDHSVNHYTNSVGKI-LGSTGRYLLIYALIVAGMVVLFLRLPSSF-- 562 Query: 457 LSTFPEDMPSREGFTLISDHFGAG-MLAPMEVVVNSKES--MKSSLENVNGVASVTG 510 PE+ +G L AG + V++ +K+ NV V +V G Sbjct: 563 ---LPEE---DQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNG 613
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 85.4 bits (211), Expect = 7e-23 Identities = 46/208 (22%), Positives = 84/208 (40%), Gaps = 10/208 (4%) Query: 1 MEKKRTRAEELGITRRKILDTARDLFMEKGYRAVSTREIAKIANITQPALYHHFEDKESL 60 K + A+E TR+ ILD A LF ++G + S EIAK A +T+ A+Y HF+DK L Sbjct: 2 ARKTKQEAQE---TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDL 58 Query: 61 YIEVVRELTQNI-QVEMHPIMQTNKAKEEQLHDMLIMLIE--EHPTNILLMIHDILNEMK 117 + E+ NI ++E+ + L ++LI ++E L++ I ++ + Sbjct: 59 FSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCE 118 Query: 118 PENQFLLYKLWQKTYLEPFQQFFERL----ENAGELRNGISAETAARYCLSTISPLFSGK 173 + + + Q+ E+ A L + AA IS L Sbjct: 119 FVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENW 178 Query: 174 GSFAQKQTTTEQIDELINLMMFGICKKE 201 Q ++ + + +++ Sbjct: 179 LFAPQSFDLKKEARDYVAILLEMYLLCP 206
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.8 bits (67), Expect = 0.002 Identities = 8/33 (24%), Positives = 15/33 (45%), Gaps = 1/33 (3%) Query: 74 LFGHWIKWLLLTIITIGIYGFWVFIKLEDWKVK 106 + W+LL ++ G F V ++ E +V Sbjct: 222 AVRTFGPWMLLALL-AGFMAFRVMLRQEKRRVS 253
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 46.2 bits (109), Expect = 2e-07 Identities = 38/250 (15%), Positives = 86/250 (34%), Gaps = 8/250 (3%) Query: 24 HADTINDMQKRQNEIEQKKSEIDKNIDSKNSELNHLESAEKDAAKELESLMKSLDDTNKK 83 + ++++ + E+E +K++++K ++ + + K E +L D K Sbjct: 104 NDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKA 163 Query: 84 LKEQEDKVSSENEKLKKLQKEMEKLRNDIRDRQKVLDNRARAIQTTGTATSYLDMIFEAD 143 L+ + ++++ K+K L+ E L + +K L+ L+ Sbjct: 164 LEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLE------ 217 Query: 144 DFKELVDRVTVVSAIVKADQNIMQDQKDDQDKLKVAESTSEKKLENLKVLAVELEVSKNN 203 E + + KA + M D K+K E+ L LE + N Sbjct: 218 --AEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNF 275 Query: 204 MESQKQEKNDLVMALANKKDLTKSEQTLLASEQGALTDEEKRLASNIAGEKAKQEAAIKA 263 + + L A + + + L ++ +K + K Sbjct: 276 STADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKL 335 Query: 264 AEEKRMQEAA 273 E+ ++ EA+ Sbjct: 336 EEQNKISEAS 345 Score = 31.6 bits (71), Expect = 0.006 Identities = 33/189 (17%), Positives = 75/189 (39%), Gaps = 5/189 (2%) Query: 22 GAHADTINDMQKRQNEIEQKKSEIDKNIDSKNSELNHLESAEKDAAKELESLMKSLDDTN 81 ++ RQ E+E+ + ++++ LE+ + E L N Sbjct: 249 KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLN 308 Query: 82 KKLKEQEDKVSSENEKLKKLQKEMEKLRNDIRDRQKVLDNRARAIQTTGTATSYLDMIFE 141 + + + E K+L+ E +KL + + + R + + A L+ Sbjct: 309 ANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEA--- 365 Query: 142 ADDFKELVDRVTVVSAIVKADQNIMQDQKDDQDKLKVAESTSEKKLENLKVLAVELEVSK 201 + ++L ++ + A ++ + + ++ + +++ A + KL L+ L ELE SK Sbjct: 366 --EHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESK 423 Query: 202 NNMESQKQE 210 E +K E Sbjct: 424 KLTEKEKAE 432
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 38.5 bits (89), Expect = 4e-05 Identities = 35/217 (16%), Positives = 80/217 (36%), Gaps = 6/217 (2%) Query: 27 ADVNTDIQNQDKKINDIKSKKTDLQSDLSGLVADLEKAQEKAKSLQGEFDKTGKELKKLN 86 A++ ++ +K L+++ + L A ++ + ++K L Sbjct: 193 AELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLE 252 Query: 87 EDIKSINERIKERETVLKERARAMQKTSNSNAYLEVILDAENLSDLVGRVSAVNQLVD-S 145 + ++ R E E L+ S LE + L + +Q+++ + Sbjct: 253 AEKAALEARQAELEKALEGAMNFSTADSAKIKTLEA--EKAALEAEKADLEHQSQVLNAN 310 Query: 146 DKSILEDQQNDEKALKTKQTAVKKKQEDQATAIHEYEAQQNKIEAQKAEK---EAIVAQL 202 +S+ D +A K + +K +E + ++ + ++A + K EA +L Sbjct: 311 RQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKL 370 Query: 203 ASDQASAENAKAGLVSERDKAAKEATARATALREATS 239 +E ++ L + D + + AL EA S Sbjct: 371 EEQNKISEASRQSLRRDLDASREAKKQVEKALEEANS 407
>SECA#SecA protein signature. Length = 901 Score = 1187 bits (3073), Expect = 0.0 Identities = 431/899 (47%), Positives = 581/899 (64%), Gaps = 65/899 (7%) Query: 1 MAGLLKKIFESG-KKDVKYLERKADEIIALADETAALSDDALREKTVEFKERVQKGETLD 59 + LL K+F S + ++ + + + I A+ E LSD+ L+ KT EF+ R++KGE L+ Sbjct: 2 LIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLE 61 Query: 60 DLLVEAFAVAREGAKRALGLYPFKVQLMGGIVLHEGNIAEMKTGEGKTLTATLPVYLNAL 119 +L+ EAFAV RE +KR G+ F VQL+GG+VL+E IAEM+TGEGKTLTATLP YLNAL Sbjct: 62 NLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL 121 Query: 120 SGEGVHVVTVNEYLAHRDAEEMGVLYNFLGLSVGLNLNALSSTEKREAYACDITYSTNNE 179 +G+GVHVVTVN+YLA RDAE L+ FLGL+VG+NL + + KREAYA DITY TNNE Sbjct: 122 TGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNE 181 Query: 180 LGFDYLRDNMVVYKEEMVQRPLAFAVIDEVDSILVDEARTPLIISGEAEKSTILYVRANT 239 GFDYLRDNM EE VQR L +A++DEVDSIL+DEARTPLIISG AE S+ +Y R N Sbjct: 182 YGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNK 241 Query: 240 FVRTLTEEE-----------DYTVDIKTKSVQLTEDGMTKGENYF-------DVENLFDL 281 + L +E ++VD K++ V LTE G+ E + E+L+ Sbjct: 242 IIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSP 301 Query: 282 ENTVILHHIAQALKANYTMSLDVDYVVQDDEVLIVDQFTGRIMKGRRFSEGLHQALEAKE 341 N +++HH+ AL+A+ + DVDY+V+D EV+IVD+ TGR M+GRR+S+GLHQA+EAKE Sbjct: 302 ANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKE 361 Query: 342 GVTIQNESKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFRDIYNMRVIEIPTNKVIIRD 401 GV IQNE++T+A+ITFQNYFR+Y+KLAGMTGTA TE EF IY + + +PTN+ +IR Sbjct: 362 GVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRK 421 Query: 402 DRPDLIYTTIEAKFNAVVEDIAERHAKGQPVLVGTVAIETSELISSKLKRKGIKHDVLNA 461 D PDL+Y T K A++EDI ER AKGQPVLVGT++IE SEL+S++L + GIKH+VLNA Sbjct: 422 DLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNA 481 Query: 462 KQHEREADIIKHAGERGAVVIATNMAGRGTDIKLG------------------------- 496 K H EA I+ AG AV IATNMAGRGTDI LG Sbjct: 482 KFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADW 541 Query: 497 ----EGTIEAGGLAVIGTERHESRRIDNQLRGRSGRQGDPGVTQFYLSMEDELMRRFGSD 552 + +EAGGL +IGTERHESRRIDNQLRGRSGRQGD G ++FYLSMED LMR F SD Sbjct: 542 QVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASD 601 Query: 553 NMKSMMERFGMAED-AIQSKMVSRAVESAQRRVEGNNFDSRKQVLQYDDVLRQQREVIYK 611 + MM + GM AI+ V++A+ +AQR+VE NFD RKQ+L+YDDV QR IY Sbjct: 602 RVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYS 661 Query: 612 QRYEVINAENSLREIIEQMIQRTVNFIVSSNASSHEPEEAWNLQGIIDYVDANLLPEGTI 671 QR E+++ + + E I + + + + EE W++ G+ + + + + I Sbjct: 662 QRNELLDVSD-VSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPI 720 Query: 672 T--LEDLQNRTSEDIQNLILDKIKAAYDEKETLLPPEEFNEFEKVVLLRVVDTKWVDHID 729 L+ E ++ IL + Y KE ++ E FEK V+L+ +D+ W +H+ Sbjct: 721 AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLA 780 Query: 730 AMDHLRDGIHLRAYGQIDPLREYQSEGFEMFEAMVSSIDEDVARYIMKAEIR-------- 781 AMD+LR GIHLR Y Q DP +EY+ E F MF AM+ S+ +V + K ++R Sbjct: 781 AMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEEL 840 Query: 782 ---QNLEREQVAKGEAINPAEGKPEAKRQPIRK--DQHIGRNDPCPCGSGKKYKNCHGK 835 + +E E++A+ + ++ + A + ++ +GRNDPCPCGSGKKYK CHG+ Sbjct: 841 EQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGR 899
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 4e-18 Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 2/114 (1%) Query: 4 KIMIVDDHQLFREGIKRILELEDSFEVVAEAENGKNIVAKVREYKPDIVLMDINMPTVNG 63 I++ DD R + + L ++V N + + D+V+ D+ MP N Sbjct: 5 TILVADDDAAIRTVLNQALSRAG-YDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 64 LDATEMLVRQFPSIKVIVLTIHDTDEYVTEALRAGAVGYLLKEMDAHELVEAVK 117 D + + P + V+V++ +T +A GA YL K D EL+ + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 435 bits (1120), Expect = e-156 Identities = 162/335 (48%), Positives = 238/335 (71%), Gaps = 5/335 (1%) Query: 2 AKDVGIDLGTANVLIHVKGRGIVVNEPAVVAINNKTG----QVLAVGTEARDMVGRTPGD 57 + D+ IDLGTAN LI+VKG+GIV+NEP+VVAI V AVG +A+ M+GRTPG+ Sbjct: 10 SNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGRTPGN 69 Query: 58 ITAIKPMKDGVIADFDIVQEMLRFFIQKLNLKTFFS-RPRILICCPTNITSVEQKAIREV 116 I AI+PMKDGVIADF + ++ML+ FI++++ +F PR+L+C P T VE++AIRE Sbjct: 70 IAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRES 129 Query: 117 AEKSGGKQVFLEEEPKVAAIGAGMEIFEPSGNMIIDIGGGTADVAVLSMGDIVTSQSVKV 176 A+ +G ++VFL EEP AAIGAG+ + E +G+M++DIGGGT +VAV+S+ +V S SV++ Sbjct: 130 AQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRI 189 Query: 177 AGNKWDADILNYVKRKYNLLIGERTAENIKVTIGTACQGAKEEKMEIRGRDLVSGLPKTI 236 G+++D I+NYV+R Y LIGE TAE IK IG+A G + ++E+RGR+L G+P+ Sbjct: 190 GGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGF 249 Query: 237 SITSSEVEEAIHDSLHLMVLAAKQVLEQTPPELSADIIDRGIIMTGGGSLLHGLDELMSE 296 ++ S+E+ EA+ + L +V A LEQ PPEL++DI +RG+++TGGG+LL LD L+ E Sbjct: 250 TLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLME 309 Query: 297 QLKVPVLITENPLDVVALGTGILLDSLTNKKRNRF 331 + +PV++ E+PL VA G G L+ + + F Sbjct: 310 ETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLF 344
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 6e-04 Identities = 22/101 (21%), Positives = 42/101 (41%), Gaps = 20/101 (19%) Query: 359 NLLTNAIKFTPQGGNIQVRLYEDTTNVFVEVQDSGVGISKVDMTKIFDRFYKANESRTRE 418 N + + I PQGG I ++ +D V +EV+++G K Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK------------------NT 307 Query: 419 EGSSGLGLS-ICQKIITLHHGEVTVQ-SSLEKGTTFTVKLP 457 + S+G GL + +++ L+ E ++ S + V +P Sbjct: 308 KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 99 bits (249), Expect = 1e-26 Identities = 39/123 (31%), Positives = 65/123 (52%), Gaps = 1/123 (0%) Query: 4 ILVVDDDRHILKLVGHYLRAEGFHVLEASDGVEAEKIVETEQVHLAVIDVMMPNMDGFEL 63 ILV DDD I ++ L G+ V S+ + + L V DV+MP+ + F+L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 CQKMRASYPDIPVIMLTAKDALADKSRGFEVGTDDYVTKPFEPEELIFRI-RALLRRSNQ 122 +++ + PD+PV++++A++ + E G DY+ KPF+ ELI I RAL + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 123 ASE 125 S+ Sbjct: 126 PSK 128
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 139 bits (351), Expect = 3e-38 Identities = 107/418 (25%), Positives = 198/418 (47%), Gaps = 19/418 (4%) Query: 16 SYSRSLL-----VVTMIIGAFVAILNQTLLATALPMIMDDLHITAATGQWLTTAFLLTNG 70 SYS+S L ++ + I +F ++LN+ +L +LP I +D + A+ W+ TAF+LT Sbjct: 4 SYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFS 63 Query: 71 IMIPITALLIEKISSKTLFITAMTVFTIGTIIASVAGS-FPILLTGRIVQAAGAGIMMPL 129 I + L +++ K L + + + G++I V S F +L+ R +Q AGA L Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL 123 Query: 130 LQTIFLLIFPREKRGAAMGLMGLVIAFAPAIGPTLSGWIVDSYDWRVLFLILIPIAVIDI 189 + + P+E RG A GL+G ++A +GP + G I W L LI + I +I + Sbjct: 124 VMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITV 182 Query: 190 ILAFFGMKKVVKLTDTKIDFLSIVMSSIGFGALLYGFSSAGNDGWGDTTVITMLIVGVVV 249 +KK V++ D I++ S+G + +S I+ LIV V+ Sbjct: 183 PFLMKLLKKEVRIKGH-FDIKGIILMSVGIVFFMLFTTSY---------SISFLIVSVLS 232 Query: 250 IALFVWRQLVIDNPMLELHVFKYPVFSLSVILGSIVTMAMIGAEIVLPLYIQTIRGESAL 309 +FV + +P ++ + K F + V+ G I+ + G ++P ++ + S Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 310 QSG-LLLLPGAIIMGIMSPITGIIFDKIGAKWLTITGVTILTIGTIPFMFLTMDTPLWYI 368 + G +++ PG + + I I GI+ D+ G ++ GVT L++ + FL T + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMT 352 Query: 369 VVFYAVRFFGISMAMMPVSTAGMNALPNHLINHGSAVNNTIRQIAGSIGTAVLITVLT 426 ++ V G+S +ST ++L G ++ N ++ G A++ +L+ Sbjct: 353 IIIVFV-LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.1 bits (166), Expect = 8e-16 Identities = 20/74 (27%), Positives = 38/74 (51%) Query: 2 KEKKQRIIKSAKEVFQKQGYLKTSVQDMVDAAGISKGTFYNYFTSKEELAIVIFKQEYSV 61 +E +Q I+ A +F +QG TS+ ++ AAG+++G Y +F K +L I++ S Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 62 LHQRLEYTMAQDGA 75 + + A+ Sbjct: 70 IGELELEYQAKFPG 83
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 84.8 bits (209), Expect = 3e-20 Identities = 56/174 (32%), Positives = 83/174 (47%), Gaps = 15/174 (8%) Query: 32 RTAQVNLTTSQQAFIDEILPAAQDGYRDGKLLTSVTLAQAILESNWGESGL----SQNSK 87 R +L +AF+ ++ AQ + + + LAQA LES WG+ + + S Sbjct: 139 RNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSY 198 Query: 88 NLFGIK--GTYKGKSVSMGTMEASGSTT----ANFRVYPSWKESIEDHTALITENARYQD 141 NLFG+K G +KG + T E A FRVY S+ E++ D+ L+T N RY Sbjct: 199 NLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAA 258 Query: 142 AVDETDYRKALQAIKDGGYATDPDYVSKLVAIIERYNLDKYDVIYDKIESNQSL 195 + QA++D GYATDP Y KL +I+ + I DK+ S+ Sbjct: 259 VTTAASAEQGAQALQDAGYATDPHYARKLTNMIQ-----QMKSISDKVSKTYSM 307
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 8e-23 Identities = 34/131 (25%), Positives = 64/131 (48%), Gaps = 1/131 (0%) Query: 3 SKRLVLIVEDEDGISNFISAVLTASDYSVIKAVNGKEALEQTASHSPDVVLLDLGLPDME 62 + +L+ +D+ I ++ L+ + Y V N A+ D+V+ D+ +PD Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GLDVLRDIR-VWSKVPIIVVSARDHEREKVTALDLGADDYITKPFGTSELLARIRTALRH 121 D+L I+ +P++V+SA++ + A + GA DY+ KPF +EL+ I AL Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 122 IQPSSKESPND 132 + + +D Sbjct: 122 PKRRPSKLEDD 132
>PF06580#Sensor histidine kinase Length = 349 Score = 39.8 bits (93), Expect = 4e-05 Identities = 28/131 (21%), Positives = 53/131 (40%), Gaps = 11/131 (8%) Query: 708 NLIRG-IKDDSGWLIRMVENLLSVTRISEGLVSLERAPEAVE-EIVGEAVGRIKKRFRDR 765 N IR I +D M+ +L + R S + + A E +V + +F DR Sbjct: 180 NNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDR 239 Query: 766 -TIHVKVPRDLLMVPMDGTLIEQVLINLMENALRHG----GTGAEVWVDVTKTKQSAIFS 820 ++ ++ V + ++ Q L+ EN ++HG G ++ + TK + Sbjct: 240 LQFENQINPAIMDVQVP-PMLVQTLV---ENGIKHGIAQLPQGGKILLKGTKDNGTVTLE 295 Query: 821 VRDNGKGIPEN 831 V + G +N Sbjct: 296 VENTGSLALKN 306
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 32.4 bits (73), Expect = 0.008 Identities = 17/81 (20%), Positives = 36/81 (44%), Gaps = 13/81 (16%) Query: 73 NFAEAIAEGRGRAQADSLKMARKDV-------------LARKLKNVDDKTDVIEVASNDL 119 NF +A+A+ + D +K A+KD+ + +KL++ + +E + Sbjct: 590 NFNKAVADAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNKMEAKAQAN 649 Query: 120 KKGDIVYVLANEQIPMDGEVI 140 + D ++ L N++ D I Sbjct: 650 SQKDEIFALINKEANRDARAI 670
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.7 bits (139), Expect = 1e-12 Identities = 32/194 (16%), Positives = 78/194 (40%), Gaps = 12/194 (6%) Query: 3 TNESIMDATLCMMAKHGIKGSTTRQLAEAAGINEATIFKKFKSKDNLIHMTLEVQFESMK 62 T + I+D L + ++ G+ ++ ++A+AAG+ I+ FK K +L E+ ++ Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 63 AEINQFFDKDFESAKVFLRQAS--QFISDIYEKYRDFMVISV--REMGSKDMEFID---P 115 ++ K LR+ S + E+ R ++ + + +M + Sbjct: 72 ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQR 131 Query: 116 SIVEYLYERVNEKVKEMVPSKNSAQ--EADAISLILNSVILLIMVEKVRDDIYKRPPTIT 173 ++ Y+R+ + +K + +K ++I+ I +M + + + Sbjct: 132 NLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP---QSFDLK 188 Query: 174 TTADSLADVLLKLL 187 A +LL++ Sbjct: 189 KEARDYVAILLEMY 202
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 58.6 bits (141), Expect = 2e-11 Identities = 56/235 (23%), Positives = 95/235 (40%), Gaps = 30/235 (12%) Query: 82 TAKQTVGPQQTETKEQTKTPEEKQAATNQVEKAPAEPATVSNPDNATSSSTPATYNLLQK 141 T +Q + + T E NQ + A N D++ + Sbjct: 99 TPEQPLPEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPRNYDDSLPGDS--------- 149 Query: 142 SALRSGATVQSFIQTIQASSSQIAAENDLYASVMIAQAILESAYGTSELGSA---PNYNL 198 ++F+ + + + ++ + +++AQA LES +G ++ P+YNL Sbjct: 150 ---------KAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNL 200 Query: 199 FGIK--GAYNGQSYTKQTLEDDGKGNYYTITAKFRKYPSYHQSLEDYAQVIRKGPSWNPN 256 FG+K G + G T E + G + AKFR Y SY ++L DY ++ + NP Sbjct: 201 FGVKASGNWKGPVTEITTTEYE-NGEAKKVKAKFRVYSSYLEALSDYVGLLTR----NPR 255 Query: 257 YYSKAWKSNTTSYKDATKALTGTYATDTAYATKLNDLISRYNLTQYDSGKTTGGN 311 Y A + ++ + A YATD YA KL ++I + KT N Sbjct: 256 Y--AAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDKVSKTYSMN 308
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 26.7 bits (59), Expect = 0.023 Identities = 19/100 (19%), Positives = 39/100 (39%), Gaps = 18/100 (18%) Query: 31 EASQEKWRFHQELENLSEQIRYIYQKRDYDASEDLPKAYHLISSIQEEGE----WM-VKN 85 E W L E + K + S+ + Y L ++ E W+ ++N Sbjct: 93 ETGGNAW-----FTKLVENAKKTENKDYFAVSDGVDVIY-LEGQNEKGKEDPHAWLNLEN 146 Query: 86 AVTHLENESE-------EHQTLYKKQVTAYEEELHQLKKE 118 + +N ++ ++ Y+K + Y ++L +L KE Sbjct: 147 GIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKE 186
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 42.1 bits (99), Expect = 9e-07 Identities = 35/158 (22%), Positives = 66/158 (41%), Gaps = 17/158 (10%) Query: 1 MKIHKLTWVLLIGLLLLSACSTEQPNLYLSAN--------AAAVYSVENGEALYEQNADK 52 M+ +L + L+ L L+ ++ QP + + + +G L AD+ Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE 60 Query: 53 VMPIASLSKLMTAFLVLEAVDNNELSWDEKLDLVRLDDPSAVSLYAITQKR---TWSVRD 109 P+ S K++ VL VD + + K+ + D V +++K +V + Sbjct: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQD---LVDYSPVSEKHLADGMTVGE 117 Query: 110 LYSAMLTMSANDAAETLGDRLDGADFPKEMNNQAKKLG 147 L +A +TMS N AA L + G P + +++G Sbjct: 118 LCAAAITMSDNSAANLLLATVGG---PAGLTAFLRQIG 152
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 44.6 bits (105), Expect = 1e-08 Identities = 19/78 (24%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Query: 1 MKINGFTLLEMLLVLTISFTLITLTIFPISSTLSTLREKQLLEEIKASIYYAQINAVATN 60 M+ GFTLLEM+L+L + + + ++ Q L +A + + Q + T Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDD-SAAQTLARFEAQLRFVQQRGLQTG 59 Query: 61 QDTFISFDPTKNQLITYT 78 Q +S P + Q + Sbjct: 60 QFFGVSVHPDRWQFLVLE 77
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 47.2 bits (112), Expect = 5e-10 Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 4/92 (4%) Query: 9 RDERGFTLVEMLIVLLVVSVLLLLTIPNIVSQSKSINDKGCEAFISMVQGQVQSYQLDKN 68 +RGFTL+E+++V++++ VL L +PN++ + + + + I ++ + Y+LD + Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNH 64 Query: 69 SIPS----VADLVSGGYLKANQKSCPNGNSIK 96 P+ + LV L + IK Sbjct: 65 HYPTTNQGLESLVEAPTLPPLAANYNKEGYIK 96
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 73.7 bits (181), Expect = 1e-16 Identities = 65/352 (18%), Positives = 146/352 (41%), Gaps = 21/352 (5%) Query: 5 QRTNWKDDGEFLIRVASLLEKGFSLDATISYL--SITSPKYCKRYERIITSLANGNSFSY 62 R + D ++A+L+ L+ + + P + + + + G+S + Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 63 ALSKNG--FPDFICSQLHYASSHGYFLQTIHETGVHMKRKAEEKNALMKTFQYPLVLFST 120 A+ F C+ + + G+ ++ + +++ + ++ + + YP VL Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 121 VILVFFLLRIFLLPKFELLFTQ------LSTNGTVGTNFTYFLLEKVPILLGIFLLSLFL 174 I V +L ++PK F LST +G + + P +L LL+ F+ Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGM--SDAVRTFGPWMLLA-LLAGFM 239 Query: 175 IFSFIIRKQKQKNAYDRAYFYCRIPYIRQFSRIHYSQYLSRELGYLLKSGLSITHIMHLF 234 F ++R++K++ ++ R +P I + +R + +R L L S + + M + Sbjct: 240 AFRVMLRQEKRRVSFHRRLL--HLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRIS 297 Query: 235 AQEESPAFFQEIARQILPTLEQGLSLTKALEKMPIFEKELYYIAIHGEKNGNLA---EEF 291 S + + + +G+SL KALE+ +F + ++ GE++G L E Sbjct: 298 GDVMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERA 357 Query: 292 LFYYNLCHQKSLQKTEKLFSFIQPIVFIVIGILIVSIYLSILYPMFSMVNQI 343 + + LF +P++ + + +++ I L+IL P+ + + Sbjct: 358 ADNQDREFSSQMTLALGLF---EPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 160 bits (406), Expect = 3e-46 Identities = 75/353 (21%), Positives = 142/353 (40%), Gaps = 38/353 (10%) Query: 2 SKIIGIDLGTTNSAVAVLEGGEAKIIPNPEGARTTPSVVGFKNGERQVGEVAKRAAITNP 61 S + IDLGT N+ + V G P+ R G VG AK+ P Sbjct: 10 SNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDR--AGSPKSVAAVGHDAKQMLGRTP 67 Query: 62 NTISSIKRHMGTNYKETIEGKDYSPQEISAIILQYLKSYAEDYLGETVDKAVITVPAYFN 121 I++I R M K+ + + +++ ++ + S + + ++ VP Sbjct: 68 GNIAAI-RPM----KDGVIADFFVTEKMLQHFIKQVHS---NSFMRPSPRVLVCVPVGAT 119 Query: 122 DAQRQATKDAGKIAGLEVERIINEPTAAALAYGMDKTETDQTILVFDLGGGTFDVSILEL 181 +R+A +++ + AG +I EP AAA+ G+ +E +V D+GGGT +V+++ L Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSE-ATGSMVVDIGGGTTEVAVISL 178 Query: 182 GDGVFEVHSTAGDNELGGDDFDKKIIDYLVAEFKKDNGIDLSQDKMALQRLKDAAEKAKK 241 V + +GGD FD+ II+Y+ + G + AE+ K Sbjct: 179 NGVV-----YSSSVRIGGDRFDEAIINYVRRNYGSLIG-------------EATAERIKH 220 Query: 242 DLS----GVTSTQISLPFITAGEAGPLHLEVTLTRAKFDELTHDLVERTIAPTRQALKDA 297 ++ G +I + E P + + + L + + ++ AL+ Sbjct: 221 EIGSAYPGDEVREIEVRGRNLAEGVPRGFTLN-SNEILEAL-QEPLTGIVSAVMVALEQC 278 Query: 298 --NLSASDIDQ-VILVGGSTRIPAVQETIKKELGKEPHKGVNPDEVVAMGAAI 347 L++ ++ ++L GG + + + +E G +P VA G Sbjct: 279 PPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGK 331
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 28.9 bits (64), Expect = 0.012 Identities = 16/78 (20%), Positives = 33/78 (42%) Query: 6 NKKERLADEIEQEELNILDEAEEAVEEEATADTLTEEQAKILELENKLDEVENRYLRMQA 65 + E+ EIE+E+ + + A EE L+EE + + KL ++ ++M Sbjct: 151 QEAEQRRKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDG 210 Query: 66 DFENVKKRHIADRDASQK 83 + + + R + A Sbjct: 211 EIKTLNSRLSSSIHARDA 228
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 53.6 bits (129), Expect = 3e-10 Identities = 68/350 (19%), Positives = 125/350 (35%), Gaps = 55/350 (15%) Query: 4 NVLVTGGTGFLGMHIIFQLLQQGYQVK-----TTVRSLKSKEKVIEILQNNGITDFTHLS 58 LVTG GF+G H+ +LL+ G+QV + K+ +E+L G Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQ------ 55 Query: 59 FVELDLSKDEGWKEAMLDCE----YVLSVASPVFFGKFKNEEELISPAIEGITRILQAAK 114 F ++DL+ EG + ++ V + +N + G IL+ + Sbjct: 56 FHKIDLADREGMTDLFASGHFERVFISPHRLAVRYS-LENPHAYADSNLTGFLNILEGCR 114 Query: 115 EAKVKRVVMTSNFGAIGFSNADKNSITTEAYWTDELAKGLSAYEKSKLIAEKEAWKFMEN 174 K++ ++ S+ G + K +T+ D + +S Y +K E A + Sbjct: 115 HNKIQHLLYASSSSVYGLN--RKMPFSTD----DSVDHPVSLYAATKKANELMAHTYSHL 168 Query: 175 ----ETELEFATINPVAIFGPSQSNHVSGSFDLLKNLLNGSMKRVINIPLNVVDARD--- 227 T L F T ++GP ++ F K +L G + I++ RD Sbjct: 169 YGLPATGLRFFT-----VYGPWGRPDMA-LFKFTKAMLEG---KSIDVYNYGKMKRDFTY 219 Query: 228 ---VADLHIRAMIT-PEANGERFIASADGEISMAD-----IAHLLQRERPELVDKMPKKT 278 +A+ IR P A+ + + + S+A I + E + + + Sbjct: 220 IDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDAL 279 Query: 279 LPNAAIRAAALFSKHAKEGELMINMNRQISNSKARDVLGWKPISTKEEAV 328 A L E +V+G+ P +T ++ V Sbjct: 280 GIEAKKNMLPLQPGDVLETSADT--------KALYEVIGFTPETTVKDGV 321
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 167 bits (425), Expect = 1e-46 Identities = 98/438 (22%), Positives = 183/438 (41%), Gaps = 87/438 (19%) Query: 12 KIRNFSIIAHIDHGKSTLADRILEQTGALTHR----EMKNQLLDSMDLERERGITIKLNA 67 KI N ++AH+D GK+TL + +L +GA + D+ LER+RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGA-ITELGSVDKGTTRTDNTLLERQRGITIQTGI 60 Query: 68 VQLKYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYL 127 ++ E ++IDTPGH+DF EV RSL+ +GAIL++ A G++AQT + Sbjct: 61 TSFQW-----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHA 115 Query: 128 ALDNDLEILPVINKIDLPAADPERVREEIEDVIG-------------------------- 161 + + INKID D V ++I++ + Sbjct: 116 LRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQW 175 Query: 162 ---LDASDAVLASAKSGIGI--EDI--------------------------LEQIVE--- 187 ++ +D +L SG + ++ ++ ++E Sbjct: 176 DTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT 235 Query: 188 -KVPEPSGDVNKPLKALIFDSVFDAYRGVIANIRIMDGVVKAGDRIKMMSNGKEFEVTEV 246 K + L +F + R +A IR+ GV+ D +++ K ++TE+ Sbjct: 236 NKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-KITEM 294 Query: 247 GVF-SPKATPRDELLVGDVGYLTAAIKNVGDTRVGDTITLANNPAEEALDGYRKLNPMVY 305 + + D+ G++ L + +GDT L P E ++ P++ Sbjct: 295 YTSINGELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLL---PQRERIENPL---PLLQ 347 Query: 306 CGLYPIDSSKYNDLRDALEKLELNDSALQFE--AETSQALGFGFRCGFLGLLHMEIIQER 363 + P + L DAL ++ +D L++ + T + + FLG + ME+ Sbjct: 348 TTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEII-----LSFLGKVQMEVTCAL 402 Query: 364 IEREFNIDLITTAPSVIY 381 ++ ++++++ P+VIY Sbjct: 403 LQEKYHVEIEIKEPTVIY 420 Score = 45.6 bits (108), Expect = 5e-07 Identities = 19/80 (23%), Positives = 32/80 (40%), Gaps = 2/80 (2%) Query: 410 EPYVKATVMVPNDYVGAVMELAQNKRGNFITMEYLDDIRVSIVYEIPLSEIVYDFFDQLK 469 EPY+ + P +Y+ A N + + ++ V + EIP I ++ L Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNE-VILSGEIPARCI-QEYRSDLT 594 Query: 470 SSTKGYASFDYELIGYKASK 489 T G + EL GY + Sbjct: 595 FFTNGRSVCLTELKGYHVTT 614
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 4e-18 Identities = 23/119 (19%), Positives = 58/119 (48%), Gaps = 2/119 (1%) Query: 2 KLLMIEDNVSVCEMIEMFFMKEEIDATFVHDGKMGYEAFFKDDYDIAIIDLMLPNMDGMT 61 +L+ +D+ ++ ++ + D + + D D+ + D+++P+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ICRKIREV-SDVPIIILTAKESESDQVLGLEMGADDYVTKPFSPLTLMARI-KAVTRRK 118 + +I++ D+P+++++A+ + + E GA DY+ KPF L+ I +A+ K Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 6e-04 Identities = 25/154 (16%), Positives = 53/154 (34%), Gaps = 35/154 (22%) Query: 330 KEFLELIKEQLDYVASEK---GNTITVAIDKDMAIYADYDRLTQVFINIVKNSV-----Q 381 + L ++ Y+ + + + AI D + +V+N + Q Sbjct: 219 ADELTVVD---SYLQLASIQFEDRLQFENQINPAIM-DVQVPPMLVQTLVENGIKHGIAQ 274 Query: 382 FTENGQITLTGTQDYKESVLTITDTGIGMNTEELEQIWERFYKADMSRTNTAFGESGIGL 441 + G+I L GT+D L + +TG E +G GL Sbjct: 275 LPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE-------------------STGTGL 315 Query: 442 SIVKQLIEY---HDGSITVTSEPNKGTSFTIRLP 472 V++ ++ + I ++ + K + + +P Sbjct: 316 QNVRERLQMLYGTEAQIKLSEKQGKVNA-MVLIP 348
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 37.2 bits (86), Expect = 2e-05 Identities = 29/184 (15%), Positives = 58/184 (31%), Gaps = 39/184 (21%) Query: 33 VLLSMDDFERAELFFKRALELDDTVPAAYYSLGNLYYELERYQEAADSFQNATKQGMENG 92 L+M+ F + E+ YSL Y+ +Y++A FQ + Sbjct: 11 YQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDS 70 Query: 93 DLFFMLGMSFVQMEELTLAMPYLLRSVELNPEDGEALFQYGIVLARSGFYEDAINMLERV 152 F LG M G Y+ AI+ Sbjct: 71 RFFLGLGACRQAM----------------------------------GQYDLAIHSYSYG 96 Query: 153 LLVKPEDPDALYNIGAAYLAWQGDIVLAKNYFERAIATGASH----ELAENALNAIQDLE 208 ++ ++P ++ L +G++ A++ A A EL+ + ++ ++ Sbjct: 97 AIMDIKEPRFPFHAAECLLQ-KGELAEAESGLFLAQELIADKTEFKELSTRVSSMLEAIK 155 Query: 209 NEAE 212 + E Sbjct: 156 LKKE 159 Score = 36.8 bits (85), Expect = 2e-05 Identities = 22/128 (17%), Positives = 38/128 (29%), Gaps = 4/128 (3%) Query: 21 PSDPVGYINFGNVLLSMDDFERAELFFKRALELDDTVPAAYYSLGNLYYELERYQEAADS 80 + +E A F+ LD + LG + +Y A S Sbjct: 33 SDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHS 92 Query: 81 FQNATKQGMENGDLFFMLGMSFVQMEELTLAMPYLLRSVELNPEDGEALFQYGIVLARSG 140 + ++ F +Q EL A L + EL + E + + R Sbjct: 93 YSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTE----FKELSTRVS 148 Query: 141 FYEDAINM 148 +AI + Sbjct: 149 SMLEAIKL 156 Score = 34.5 bits (79), Expect = 1e-04 Identities = 15/83 (18%), Positives = 27/83 (32%) Query: 2 QEGNLEEAVKLFTEVIEEHPSDPVGYINFGNVLLSMDDFERAELFFKRALELDDTVPAAY 61 Q G E+A K+F + D ++ G +M ++ A + +D P Sbjct: 48 QSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFP 107 Query: 62 YSLGNLYYELERYQEAADSFQNA 84 + + EA A Sbjct: 108 FHAAECLLQKGELAEAESGLFLA 130 Score = 27.2 bits (60), Expect = 0.037 Identities = 10/58 (17%), Positives = 17/58 (29%) Query: 2 QEGNLEEAVKLFTEVIEEHPSDPVGYINFGNVLLSMDDFERAELFFKRALELDDTVPA 59 G + A+ ++ +P + LL + AE A EL Sbjct: 82 AMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTE 139
>PF05272#Virulence-associated E family protein Length = 892 Score = 35.4 bits (81), Expect = 4e-04 Identities = 25/109 (22%), Positives = 46/109 (42%), Gaps = 10/109 (9%) Query: 1 MAIQPLAYRMRPKALDEIVGQTHLVGK-DKIINRMVKAKQLSSMILYGPPGIGKTSIASA 59 + P Y+ R ++VG+ L+G +++ K S++L G GIGK+++ + Sbjct: 558 LGKTPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFD--YSVVLEGTGGIGKSTLINT 615 Query: 60 IAGSTKYAFRTLNAVTNNKKDMEVVAAEAKMSGTVILLLDEVHRLDKAK 108 + G + T + K E +A G V L E+ +A Sbjct: 616 LVG-LDFFSDTHFDIGTGKDSYEQIA------GIVAYELSEMTAFRRAD 657
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 52.8 bits (127), Expect = 2e-09 Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 27/132 (20%) Query: 22 DLVIKNGRIINVFSGEIMDGDIAIKNGYIAGIGSF--PD-----------AEKIIDAAGA 68 D VI N I++ G I+ DI +K+G IA IG PD ++I G Sbjct: 69 DTVITNALILD-HWG-IVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGK 126 Query: 69 FIAPGFIDAHVHVESAMVTPAEFARVLLPNGVTTIV---TDPHEIANVA----GEKGIEF 121 + G +D+H+H + P + L +G+T ++ T P G I Sbjct: 127 IVTAGGMDSHIH----FICP-QQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIAR 181 Query: 122 MLEDAKGAPLDM 133 M+E A P+++ Sbjct: 182 MIEAADAFPMNL 193
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 37.1 bits (86), Expect = 5e-05 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 6/41 (14%) Query: 1 MKILVFGGTRFFGKKLVERLVSEGHDVTIGTRGKTEDNFGD 41 MK LV G F G + +RL+ GH V +G DN D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQV-VGI-----DNLND 35
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.6 bits (178), Expect = 4e-17 Identities = 30/118 (25%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Query: 3 KVYIVEDDEVIRDTIRKHLSKWGFEIGVVEDFNNILQEFLAFEPQLVILDVNLPFFDGFY 62 + + +DD IR + + LS+ G+++ + + + + A + LV+ DV +P + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 WCNQIREV-SNVPIIFLSSRNSRMDQIMGMNMGADYYIEKPVDLDVLMARINALLRRT 119 +I++ ++P++ +S++N+ M I GA Y+ KP DL L+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.006 Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 8/53 (15%) Query: 41 GPSGAGKSTLLNVLSSIDKPTSGEIEIGGKQISTMN--GK------ELAVFRR 85 G G GKSTL+N L +D + +IG + S G E+ FRR Sbjct: 603 GTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRR 655
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 29.0 bits (65), Expect = 0.011 Identities = 12/69 (17%), Positives = 23/69 (33%), Gaps = 3/69 (4%) Query: 49 EVLRRLEEYFSDKSDQGLNLSSFPKYMMETVKKASYVPAKDDDVERLKQLLVEFGSDVRA 108 ++ LE + S+Q L + + A + + + + E G + Sbjct: 120 QLKAYLEGKSEEPSEQFKMLCGLRDALKGRPELAHLSHLVEQALVSMAE---EQGETIVL 176 Query: 109 SDRITVSAA 117 RIT A Sbjct: 177 GARITPEAY 185
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 128 bits (324), Expect = 7e-43 Identities = 67/91 (73%), Positives = 77/91 (84%) Query: 1 MANKTDLVNSVAELADLSKKDAAKAVEAVFETIQTSLSKGEKVQLIGFGNFEVRERAARK 60 MANK DL+ VAE +L+KKD+A AV+AVF + + L+KGEKVQLIGFGNFEVRERAARK Sbjct: 1 MANKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARK 60 Query: 61 GRNPRTKEEIDIPASKVPAFKPGKALKEAVK 91 GRNP+T EEI I ASKVPAFK GKALK+AVK Sbjct: 61 GRNPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 31.7 bits (72), Expect = 0.006 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 10/79 (12%) Query: 45 SAEWLGKEFNIIDT-GGIDLSDEPFLEQIRAQAEIAIDEADVIIFITNGREGVTDADEQV 103 S +W + NIIDT G +D FL A+ ++ D I + + ++GV + Sbjct: 62 SFQWENTKVNIIDTPGHMD-----FL----AEVYRSLSVLDGAILLISAKDGVQAQTRIL 112 Query: 104 AKILYRSNKPIVLAINKVD 122 L + P + INK+D Sbjct: 113 FHALRKMGIPTIFFINKID 131
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.1 bits (75), Expect = 0.001 Identities = 37/244 (15%), Positives = 70/244 (28%), Gaps = 44/244 (18%) Query: 6 CIAIDGPAAAGKSTVAKIVAKKLRFVYIDTGAMYRAVTYIALKNNIAYE----------D 55 + ++G GKST+ + F +Y + +AYE D Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRRAD 657 Query: 56 EKAIAALLQKTVIRFEP--GEV------QQVFVGSENVTEVIRS---------IEVTNHV 98 +A+ A R+ G Q V + N + + + V Sbjct: 658 AEAVKAFFSSRKDRYRGAYGRYVQDHPRQVVIWCTTNKRQYLFDITGNRRFWPVLVPGRA 717 Query: 99 SIVAAHPSIREALQERQQVFATEGGIVMDGRDIGTAVLPNAELKIFLLASVEERAERRYK 158 ++V + R Q+FA + + G + +I+ E R Sbjct: 718 NLVWLQ-------KFRGQLFAEALHLYLAGE---RYFPSPEDEEIYFRPEQELRLVETGV 767 Query: 159 ENMAKGFTGDLDQLKKEIEERDHLDYTRTHSPLKKAD--DAIEVDT---TSMSIDQVANK 213 + E + Y+ + + AD A+ D + M QV + Sbjct: 768 QGRLWALLTREGAPAAEGAAQK--GYSVNTTFVTIADLVQALGADPGKSSPMLEGQVRDW 825 Query: 214 ILSL 217 + Sbjct: 826 LNEN 829
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.0 bits (98), Expect = 1e-06 Identities = 26/111 (23%), Positives = 43/111 (38%), Gaps = 13/111 (11%) Query: 80 SNEVKTETESTVNVSDNTQSKEEKEKAKKAAEEKA----AAEKAAEEKKAAAEKAEADKK 135 + +ET TV + +SK ++ + A E A A++A KA + E + Sbjct: 1029 APATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQS 1088 Query: 136 KQEEDAVKAANAKKEQEAAEEKAAADKAAAEKAAAEKAEQQKANEASQQKA 186 E KE + E K A EKA E + Q+ + + Q + Sbjct: 1089 GSET---------KETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVS 1130 Score = 40.4 bits (94), Expect = 4e-06 Identities = 23/110 (20%), Positives = 41/110 (37%), Gaps = 1/110 (0%) Query: 96 NTQSKEEKEKAKKAAEEKAAAEKAAEEKKAAAEKAEADKKKQEEDAVKAANAKKEQEAAE 155 TQ+ E KE A EEKA E ++ + K++Q E A +E + Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTV 1153 Query: 156 EKAAADKAAAEKAAAEKAEQQKANEASQQKAGGSHTVKAGDTLYSIARST 205 + A + ++ + +Q S TV G+++ +T Sbjct: 1154 NIKEPQ-SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENT 1202 Score = 33.1 bits (75), Expect = 9e-04 Identities = 17/112 (15%), Positives = 41/112 (36%), Gaps = 4/112 (3%) Query: 84 KTETESTVNVSDNTQSKEEKEKAKKAAEEKAAAEKAAEEKKAAAEKAEADKKKQEEDAVK 143 K E ++T + N + +E + KA + ++ E K + E++ Sbjct: 1053 KNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKA 1112 Query: 144 AANAKKEQE----AAEEKAAADKAAAEKAAAEKAEQQKANEASQQKAGGSHT 191 +K QE ++ +++ + AE A + ++ ++T Sbjct: 1113 KVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNT 1164
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 28.6 bits (64), Expect = 0.018 Identities = 27/132 (20%), Positives = 53/132 (40%), Gaps = 9/132 (6%) Query: 9 FVSVAVLGTLAFILMMLQFPLLPSAPFLKLDFSDIPALIGGL--LFGPLAVILVELIKNV 66 F + V +A ++Q+ L S +K D I I G +F + LVE +K++ Sbjct: 88 FPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKI-NPIEGAKRIFSIKS--LVEFLKSI 144 Query: 67 LLYIVSGSPVGVPVGELANFISGLFYVLPIYYLFHWLRSTKGMVLSTAVGTVLMTGAMAV 126 L ++ + + + + L + + +++ VG V+++ A Sbjct: 145 LKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVICTVGFVVISIADYA 204 Query: 127 FNYFVLLPFYIK 138 F Y+ YIK Sbjct: 205 FEYY----QYIK 212
>PF06580#Sensor histidine kinase Length = 349 Score = 43.7 bits (103), Expect = 1e-06 Identities = 30/170 (17%), Positives = 57/170 (33%), Gaps = 40/170 (23%) Query: 443 LAPLLRKVISNFDV----LAKE-NFVELGLELET---PD-LEYSYD-PDRMEQVLI---- 488 L+ L+R + + LA E V+ L+L + D L++ + V + Sbjct: 200 LSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPML 259 Query: 489 --NLIMNAIRHTGKEGYDGKVILKQTIDVARSNLVITVSDNGSGIAEEDIPYLFERFYKV 546 L+ N I+H G + + + V + GS + Sbjct: 260 VQTLVENGIKH-GIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE--------- 309 Query: 547 DKARKRGKAVGTGIGLAIVKNIVEAHNGK---ISVESELGKGSDFIITLP 593 TG GL V+ ++ G I + + GK + ++ +P Sbjct: 310 ----------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 98.0 bits (244), Expect = 9e-26 Identities = 29/136 (21%), Positives = 63/136 (46%), Gaps = 3/136 (2%) Query: 6 RVLVVDDEDRIRRLLKMYLERENYRIEEASDGDQALSMALNNNYEVILLDLMMPGKDGIE 65 +LV DD+ IR +L L R Y + S+ + ++++ D++MP ++ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 66 VCRELRE-FKSTPVVMLTAKGEEANRVQGFEVGADDYIVKPFSPREVVLRVKAVL--RRA 122 + +++ PV++++A+ ++ E GA DY+ KPF E++ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 123 KQSSEESAGGTPGDII 138 + S E ++ Sbjct: 125 RPSKLEDDSQDGMPLV 140
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.010 Identities = 26/125 (20%), Positives = 47/125 (37%), Gaps = 7/125 (5%) Query: 246 NMFGLTAASAAAYVSIYSLSNCLGRVVWGAVSDRLGRSNTLMIIYTVIALSLLALTTLQS 305 N F AS + + L+ +G V+G +SD+LG L+ + + S Sbjct: 42 NDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHS 101 Query: 306 VVGFVIGIIGLGLCFGGTMGVFPSIVM----ENYGPKNQGVNYGIVFIGYSTAAFFAPKM 361 +I + G FP++VM +N+G +G++ + P + Sbjct: 102 FFSLLI-MARFIQGAGAAA--FPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAI 158 Query: 362 AAQIA 366 IA Sbjct: 159 GGMIA 163 Score = 29.5 bits (66), Expect = 0.025 Identities = 32/148 (21%), Positives = 55/148 (37%), Gaps = 12/148 (8%) Query: 45 VVMAFTINAAIGPIPTILGGILTDKGKAKWAILIGGILFGLGFALTGFATSTTMLYLSYG 104 V AF + +IG T + G L+D+ K +L G I+ G ++ GF + L Sbjct: 54 VNTAFMLTFSIG---TAVYGKLSDQLGIKRLLLFGIIINCFG-SVIGFVGHSFFSLLIMA 109 Query: 105 VLAGLGQGFAYSGCLSNTIR---LFPDKRGLASGLITAGMGGATIIAAPIANYLIETYNV 161 G G A L + + + RG A GLI + + + I + + Sbjct: 110 RFI-QGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW 168 Query: 162 MTAFKIMGAVYIAVVIGCSFLIRVAPAG 189 I + +I FL+++ Sbjct: 169 SYLLLIP----MITIITVPFLMKLLKKE 192
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 371 bits (955), Expect = e-127 Identities = 126/339 (37%), Positives = 189/339 (55%), Gaps = 30/339 (8%) Query: 146 DGTVIVAESVAMKQIVRVCNQIAPFDSKVLLYGESGTGKEVLSRYIHEKSKQAAGPFISI 205 DG +V S AM++I RV ++ D +++ GESGTGKE+++R +H+ K+ GPF++I Sbjct: 135 DGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194 Query: 206 NCAAIPKALFESELFGHEKGSFTGADIEKPGMLELADGGTLFLDEISEMPLELQAKMLRV 265 N AAIP+ L ESELFGHEKG+FTGA G E A+GGTLFLDEI +MP++ Q ++LRV Sbjct: 195 NMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRV 254 Query: 266 LETGEVRRLGSTTETKRRFRLISATNRNLGEMVEKGTFRRDLYYRINVVPVHIPALRERP 325 L+ GE +G T + R+++ATN++L + + +G FR DLYYR+NVVP+ +P LR+R Sbjct: 255 LQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRA 314 Query: 326 QDIIGLARQFIQKFNQKYQKDFQLSGDKTKELLSHNWPGNVRELRNKIERLVVMSGNKEV 385 +DI L R F+Q+ ++ + + + + +H WPGNVREL N + RL + + Sbjct: 315 EDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVI 374 Query: 386 TVAETDDFALDLHFKEQTKK------------------------------DSLYLKDYLQ 415 T ++ +K S L Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLA 434 Query: 416 GVEKHFILRVLEESNGNVTKAASTLGIHRSVLYRKLKTL 454 +E IL L + GN KAA LG++R+ L +K++ L Sbjct: 435 EMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 130 bits (327), Expect = 8e-39 Identities = 83/255 (32%), Positives = 129/255 (50%), Gaps = 9/255 (3%) Query: 4 LNGKVAVVTGAASGMGQQIAILFAKEGAKVVVADLNLEAAQKTVELVEKEHGTGLAVVAN 63 + GK+A +TGAA G+G+ +A A +GA + D N E +K V ++ E A A+ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 64 VTKQEDIENMINQAIEAFGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMRAT 123 V I+ + + G +DILVN AG++ L+DE W+ F++N+TGV A+ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 124 REALHIFEEKGQGVIVNIASAGGLFGSRAGAAYTASKHAVVGFTKNVGFQYANKNIRCNA 183 R ++ G IV + S + AAY +SK A V FTK +G + A NIRCN Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 184 IAPGAVNTNIGTTIYAPDEFGQERAMIGMGINPRAG-------DASEIAKVALFLASDDS 236 ++PG+ T++ +++A DE G E+ + G + G S+IA LFL S + Sbjct: 185 VSPGSTETDMQWSLWA-DENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 237 SFVNGTVITADAGWT 251 + + D G T Sbjct: 244 GHITMHNLCVDGGAT 258
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.2 bits (135), Expect = 4e-12 Identities = 17/98 (17%), Positives = 36/98 (36%) Query: 1 MDRRVKKTKKAFNQALFTLLDQKPFQQITITDIVTEADVNRGTFYKHYRDKEELLDSIIE 60 + ++T++ L Q+ ++ +I A V RG Y H++DK +L I E Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 EILMDLKSAYQDPYLHTSHFSIQTLTPSMIKIFDHVYH 98 ++ + + L +I + + Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT 102
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 29.3 bits (65), Expect = 0.007 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 5/51 (9%) Query: 46 IIKSLAADAEMAGIEAKRLLKRKQALENNVQNLKNYLQTEMERMEIRKINS 96 I++ +A A+ AG A R+QA+E+N Q + Y R E +++S Sbjct: 317 IVEQIAQQAKEAGEVA-----RQQAVESNAQAQQRYEDQHARRQEELQLSS 362
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 79.0 bits (194), Expect = 1e-18 Identities = 54/165 (32%), Positives = 84/165 (50%), Gaps = 16/165 (9%) Query: 53 QQFIQSIANDAQDLQKEEKILTSVTLAQAILESNWGKSGL----STSANNLFGIK--GSY 106 + F+ ++ AQ ++ + + LAQA LES WG+ + + NLFG+K G++ Sbjct: 150 KAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNW 209 Query: 107 EGSSVSMGTQEFSSGKAYHTQADFRKYPDKKASLVDHAQLFVNGVSGNANLYSAVIGETN 166 +G + T E+ +G+A +A FR Y +L D+ L Y+AV + Sbjct: 210 KGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPR-----YAAVTTAAS 264 Query: 167 YKEAAYAIQDAGYATDPAYAEKLISTIENYNLDQYDQIYDTVTST 211 ++ A A+QDAGYATDP YA KL + I+ Q I D V+ T Sbjct: 265 AEQGAQALQDAGYATDPHYARKLTNMIQ-----QMKSISDKVSKT 304
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 24.0 bits (52), Expect = 0.046 Identities = 12/52 (23%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Query: 9 WVFLLSLMAEFVLSSMLYVSFDMTRAIILTVGLSFF-IILITFLMPKDSEVY 59 + +S + F+ + LY S+ + +++L V L ++L L + ++VY Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVY 925
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.8 bits (80), Expect = 0.001 Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 24/134 (17%) Query: 162 ALTKYGRDLVAEVRSG-KLDPVIGRDAEIRNVIRILSRKTKNN-PVLI-GEPGVGKTAIV 218 AL + R P++GR A ++ + R+L+R + + ++I GE G GK + Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 219 EGLAQRIVRKD----------VPEGLKDKTIISLDIGSLIAGAKYRGEFEERLKAVLQEV 268 L R++ +P L I S + G + +G F Sbjct: 178 RALHDYGKRRNGPFVAINMAAIPRDL---------IESELFGHE-KGAFTGAQTRSTGRF 227 Query: 269 KQSDGQILLFIDEI 282 +Q++G LF+DEI Sbjct: 228 EQAEGG-TLFLDEI 240 Score = 33.3 bits (76), Expect = 0.004 Identities = 46/218 (21%), Positives = 75/218 (34%), Gaps = 31/218 (14%) Query: 561 EREKLLKLADVLHQKVIGQDDAVQLVSDAVLRARAGIKDPKRPIGSFIFLGPTGVGKTEL 620 R L+ ++G+ A+Q + + R + + G +G GK + Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQT----DLTL---MITGESGTGKELV 176 Query: 621 AKALAFNMFDSEDHMIRIDMSEYMEKHSVSRLVGAPPGYIGYEEGGQLTEAVRRNPYSI- 679 A+AL + I+M+ S L G E G T A R+ Sbjct: 177 ARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH--------EKGAFTGAQTRSTGRFE 228 Query: 680 ------VLLDEIEKAHPDVFNILLQVLDDGRITDSQGRLIDFKNTVIIMTSNIGSNLLLE 733 + LDEI D LL+VL G T GR + I+ +N L + Sbjct: 229 QAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKD---LKQ 285 Query: 734 RTEEGEISPELES--DVMQILQSEFKPEFLNRVDDIIL 769 +G +L +V+ + P +R +DI Sbjct: 286 SINQGLFREDLYYRLNVVPL----RLPPLRDRAEDIPD 319
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.8 bits (64), Expect = 0.016 Identities = 18/107 (16%), Positives = 43/107 (40%), Gaps = 4/107 (3%) Query: 159 ENEELIIRQIEKGVKRIYYIEQDQEVVAVAETSAENSFSAMITGVATSDEYRQRGFASTL 218 E++++ + +E+ K + + + + + + A+I +A + +YR++G + L Sbjct: 51 EDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTAL 110 Query: 219 L---KKLCCDVLAEGKKPCLFYDNPVAGEIYHRLGFEHTG-DFVMYK 261 L + + G N A Y + F D ++Y Sbjct: 111 LHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYS 157
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 1e-04 Identities = 30/192 (15%), Positives = 67/192 (34%), Gaps = 37/192 (19%) Query: 407 TIIKEESDRLHRLIMDI-------LALSRIEQNPVPENVELVEVDEVIEQSARTIFEMAT 459 +I E+ + ++ + L S Q + + + +V+ + + + Sbjct: 184 ALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLAS-IQFEDRLQF 242 Query: 460 EKNIQVIIPEKTIPSVTIETDRDKLQQILINLLSNAINYTPVDGKVEVKLIEQEAEVIIE 519 E I I + +P + +Q ++ N + + I P GK+ +K + V +E Sbjct: 243 ENQINPAIMDVQVPPML-------VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLE 295 Query: 520 VTDNGIGIPAKDIDRVFERFYRVDKARSRHSGGTGLGLSIVKHLVENCGG---RIEVESQ 576 V + G + TG GL V+ ++ G +I++ + Sbjct: 296 VENTGSLALKNTKE------------------STGTGLQNVRERLQMLYGTEAQIKLSEK 337 Query: 577 EEVGSTFRVTLP 588 + V +P Sbjct: 338 QG-KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 99.5 bits (248), Expect = 2e-26 Identities = 35/136 (25%), Positives = 77/136 (56%) Query: 3 KILVVDDEASIVTLLQFNIEKAGFEVVTAEDGRTGYELALSEKPDLIVLDLMLPEMDGIE 62 ILV DD+A+I T+L + +AG++V + T + + DL+V D+++P+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 VTKKLRQDKVNVPILMLTAKDEELDKIIGLELGADDYMTKPFSPREVVARIKAILRRTEG 122 + ++++ + ++P+L+++A++ + I E GA DY+ KPF E++ I L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 123 KAEIIEELTEDVEATI 138 + +E+ ++D + Sbjct: 125 RPSKLEDDSQDGMPLV 140
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.020 Identities = 12/33 (36%), Positives = 17/33 (51%), Gaps = 1/33 (3%) Query: 48 GRLDLAILPFIHE-LNIKTPVISCNGGLVRDFT 79 GR D+A+ F L K+ + G + RDFT Sbjct: 186 GRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFT 218
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 30.9 bits (69), Expect = 0.007 Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 3/57 (5%) Query: 55 SLDEMADHLMNKYKSSNEAMSMSINSNGK---IAYQGALTKDAKRPIIKFGFDQNQA 108 +L + + L + +S+ +S+ IN +G +A Q D+ RP++KFG +Q A Sbjct: 603 TLSQQLNTLQQQQESAKAQLSILINRSGSWADVARQSLQRFDSTRPVVKFGTEQYTA 659
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.1 bits (62), Expect = 0.030 Identities = 9/30 (30%), Positives = 14/30 (46%) Query: 37 IVGPSGAGKSTFLSIAGALLSPTEGEIAIG 66 + G G GKST ++ L ++ IG Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIG 630
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.5 bits (76), Expect = 0.001 Identities = 14/71 (19%), Positives = 21/71 (29%) Query: 129 VKQEAIQKEEAEKAEKERKEAEEKAKQEEEAAAAKAATTDENTPSDDTVYGTLASKDTLT 188 E + + E E E EEKAK E E T + +P + + Sbjct: 1088 SGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAR 1147 Query: 189 KEGDAFYKDEA 199 + E Sbjct: 1148 ENDPTVNIKEP 1158
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 25.2 bits (55), Expect = 0.047 Identities = 12/52 (23%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Query: 31 DADVEHID-VSAARSMNVDIIVTSQELAETLGTDTSAKVVIVNNYFDNAEIK 81 A EH S ++ V+I ++E L + + + ++ + AEIK Sbjct: 50 VARQEHEVFASILKNNLVEIEYIEDLISEVLVSSVALENKFISQFILEAEIK 101
>PF05043#Transcriptional activator Length = 493 Score = 32.6 bits (74), Expect = 0.006 Identities = 36/162 (22%), Positives = 64/162 (39%), Gaps = 16/162 (9%) Query: 7 RNMTLLESLVVANVYLAPENLQEELGISKRTLQYDVEKINKELDNIGLDGIQSVRGQGYY 66 R + LLE L + L E L ++R ++ D+ + + D I G Sbjct: 11 RQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLS----HVKSAFPDLIFHSSTNGIR 66 Query: 67 LLEEEKTTIKEILENREASHKVFSASERRIRILFFLLVTDARVIIDTINECNEVSRNTSL 126 ++ + + I+ + H F S IL F+ + E +S ++ Sbjct: 67 IINTDDSDIEMVY------HHFFKHSTH-FSILEFIFFNEGCQAESICKE-FYISSSSLY 118 Query: 127 QDIKQLKLALK-QFNLELAYDRKNGNMVLGDERSIRQFFIHY 167 + I Q+ +K QF E++ ++G+ER IR FF Y Sbjct: 119 RIISQINKVIKRQFQFEVSLTP---VQIIGNERDIRYFFAQY 157
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 97.2 bits (242), Expect = 5e-24 Identities = 74/311 (23%), Positives = 119/311 (38%), Gaps = 51/311 (16%) Query: 13 VNIGTIGHVDHGKTTLTAAI---TTVLAKKGYADAQAYDQIDGAPEERERGITISTAHVE 69 +NIG + HVD GKTTLT ++ + + + G D + D ER+RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDK-GTTRTDNTLLERQRGITIQTGITS 62 Query: 70 YQTDSRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVP 129 +Q ++ +D PGH D++ + + +DGAIL++SA DG QTR R++G+P Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 130 YIVVFMNKCDMV------------------------------------DDEELLELVEME 153 I F+NK D + E + V Sbjct: 123 TI-FFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 154 IRDLLTEY----EFPGDDIP------VIKGSALKALQGEADWEAKIDELMEAVDSYIPTP 203 DLL +Y ++ S G A ID L+E + + + Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSS 241 Query: 204 ERDTDKPFMMPVEDVFSITGRGTVATGRVERGQVKVGDEVEVIGIEEESKKVVVTGVEMF 263 V + R +A R+ G + + D V + E+ + T + Sbjct: 242 THRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGE 301 Query: 264 RKLLDYAEAGD 274 +D A +G+ Sbjct: 302 LCKIDKAYSGE 312
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 634 bits (1637), Expect = 0.0 Identities = 169/691 (24%), Positives = 308/691 (44%), Gaps = 67/691 (9%) Query: 9 KTRNIGIMAHIDAGKTTTTERILFYTGRIHKIGETHEGASQMDWMEQEQERGITITSAAT 68 K NIG++AH+DAGKTT TE +L+ +G I ++G +G ++ D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TAQWKGYRVNIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATTYGV 128 + QW+ +VNIIDTPGH+DF EV RSL VLDGA+ ++ A+ GV+ QT ++ G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 129 PRVVFVNKMDKIGADFLYSVGTLHERLAANAHPIQLPIGAEDTFEGIIDLIEMNALYYED 188 P + F+NK+D+ G D + E+L+A +I+ Y + Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEI------------------VIKQKVELYPN 163 Query: 189 DLGNDPHIKEIPADLKDLADEYRGKLVEAVAELDEELMMKYLEGEEITKEELKAGIRKGT 248 + ++++ + V E +++L+ KY+ G+ + EL+ Sbjct: 164 MCVTNF----------TESEQW-----DTVIEGNDDLLEKYMSGKSLEALELEQEESIRF 208 Query: 249 LNVEFYPVVCGTAFKNKGVQPMLDAVLDYLPAPTDVPAINGVLPDGEEAARHADDSEPFS 308 N +PV G+A N G+ +++ + + + T Sbjct: 209 HNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH------------------RGQSELC 250 Query: 309 SLAFKVMTDPYVGRLTFFRVYSGTLNSGSYVQNSTKGKRERVGRILQMHANHREEISIVY 368 FK+ RL + R+YSG L+ V+ S K K ++ + +I Y Sbjct: 251 GKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKIDKAY 309 Query: 369 AGDIAAAVG----LKDTTTGDTLCDEKEQIILESMEFPEPVIQVAIEPKSKADQDKMGQA 424 +G+I L GDT + E +E P P++Q +EP ++ + A Sbjct: 310 SGEIVILQNEFLKLNS-VLGDTKLLPQR----ERIENPLPLLQTTVEPSKPQQREMLLDA 364 Query: 425 LAKLAEEDPTFRAETDQETGQTLISGMGELHLDILVDRMRREFRVEANVGDPQVSYRETF 484 L ++++ DP R D T + ++S +G++ +++ ++ ++ VE + +P V Y E Sbjct: 365 LLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYME-- 422 Query: 485 RKSAQVEGKFVRQSGGRGQYGHVWIEFGPNEEGKGFEFENAIVGGVVPREYIPAVQAGLE 544 R + E + + + + P G G ++E+++ G + + + AV G+ Sbjct: 423 RPLKKAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIR 482 Query: 545 GALDNGVLAGYPLIDIKAKLYDGSYHDVDSNEMAFKVAASMALRNAAKKCDPVILEPMMA 604 + G L G+ + D K G Y+ S F++ A + L KK +LEP ++ Sbjct: 483 YGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLS 541 Query: 605 VEVVIPEEYLGDIMGNITSRRGRVDGMEARGNAQVVRAFVPLANMFGYATHLRSGTQGRG 664 ++ P+EYL + + + + N ++ +P + Y + L T GR Sbjct: 542 FKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRS 601 Query: 665 VYTMQFDHYEEVPKSIAEEIIKANGGNNKED 695 V + Y + E + + N++ D Sbjct: 602 VCLTELKGYHV---TTGEPVCQPRRPNSRID 629
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.4 bits (63), Expect = 0.009 Identities = 13/56 (23%), Positives = 19/56 (33%) Query: 81 LYLEDLYIIPEMRGKGFGTQFFSYLSKLALARDCGRFEWWCLNENKSGMDFYEKIG 136 +ED+ + + R KG GT + A + N S FY K Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHH 145
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.8 bits (134), Expect = 5e-12 Identities = 22/79 (27%), Positives = 44/79 (55%), Gaps = 3/79 (3%) Query: 2 ARLSQEIILNMAEKIIYEKGMEKTTLYDIASNLNVTHAALYKHYRNKEDLFQKLALRWLE 61 A+ +++ IL++A ++ ++G+ T+L +IA VT A+Y H+++K DLF ++ E Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI-WELSE 67 Query: 62 ETSREIFAWTQDAGQTPDD 80 E+ + + P D Sbjct: 68 SNIGELEL--EYQAKFPGD 84
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 100 bits (251), Expect = 9e-28 Identities = 70/249 (28%), Positives = 115/249 (46%), Gaps = 13/249 (5%) Query: 5 RVAFILGGSGGIGKAVVQKLVEQNFAVAVHYAGNKAKAETLVENIVKSGGEAISVGGDVA 64 ++AFI G + GIG+AV + L Q +A N K E +V ++ A + DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAA-VDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 65 DEAQMIRAFDFIESQFGGIDVVINTAGIMKLSPIATLDMDDFDLIQRTNVRGTFVVSKQA 124 D A + IE + G ID+++N AG+++ I +L ++++ N G F S+ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 125 A--LRVRNGGAIINFSTSVTRTSFPTYGAYVASKAGVESLTLILARELRGKDITVNAVAP 182 + + R G+I+ ++ + AY +SKA T L EL +I N V+P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 183 GPTATPLFLT------GKDDKTIDNLAK---ATPLERLGQPEDIAETVAFLA-GPARWVN 232 G T T + + G + +L PL++L +P DIA+ V FL G A + Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 233 GQVIFTNGG 241 + +GG Sbjct: 248 MHNLCVDGG 256
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 61.0 bits (148), Expect = 2e-12 Identities = 83/438 (18%), Positives = 159/438 (36%), Gaps = 58/438 (13%) Query: 8 RHSLIVLLVLFIGYTSVYVDKYTIGISLVTVSQDLGFDPSQKGLILSAFFLGYTLFQIPM 67 RH+ I++ + + + SV +++ + +SL ++ D P+ + +AF L +++ Sbjct: 11 RHNQILIWLCILSFFSV-LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVY 69 Query: 68 GYLNNRIGARPVLAISIIIVGLFLVIFGFGYSLLFLVVIRFLSGALGHAGYPPSVSNYIS 127 G L++++G + +L III VI G+S L+++ G A +P V ++ Sbjct: 70 GKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVA 129 Query: 128 LHIPLNKRGFAQSAMLASSGFAAFIGPLLIAQLLLSVGWRNTYYWIGFAVILI--GFLIL 185 +IP RG A + + +GP + + + W Y + +I I ++ Sbjct: 130 RYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS---YLLLIPMITIITVPFLM 186 Query: 186 IVVPKAPKID---------------------------------------LNTQKEKIKVP 206 ++ K +I K+ P Sbjct: 187 KLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDP 246 Query: 207 F--SELLKDKQLWILLLSALFINAANYGLTSWLASYLNEVRGISISEVSYISSLAG-LCI 263 F L K+ I +L I G S + + +V +S +E+ + G + + Sbjct: 247 FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSV 306 Query: 264 LIAGVVGGYFISRFFKGKEPIIIFVFCVLGAFAVYGVYLFEQLALSVICLCLCNIFLIMA 323 +I G +GG + R I F + F L I + L Sbjct: 307 IIFGYIGGILVDRRGPLYVLNIGVTFLSVS-FLTASFLLETTSWFMTIIIVFVLGGLSFT 365 Query: 324 FTTLMGLPHKLFQQSHIATKYAAINSGGVLGGFFAPMIIGDLVN---------ATNSYQS 374 T + + +Q + +N L I+G L++ QS Sbjct: 366 KTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQS 425 Query: 375 AFLFLALTLLVSGLIVLA 392 +L+ L LL SG+IV++ Sbjct: 426 TYLYSNLLLLFSGIIVIS 443
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 111 bits (278), Expect = 1e-28 Identities = 81/387 (20%), Positives = 158/387 (40%), Gaps = 20/387 (5%) Query: 34 VPAVQSDLGISSDLLSIAISLTALFSGIFIVVAGGMADKFGRVKLTYIGLILSIIGSLLL 93 +P + +D + + L I V G ++D+ G +L G+I++ GS++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 94 VVTQGS-TLLIIGRIIQGLSAACIMPATLALMKTYFDGADRQRALSYWSIGSWGGSGICS 152 V +LLI+ R IQG AA + ++ Y +R +A G G+ Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 153 FAGGAIATYMGWRWIFIISIVFALLGMLLIKGTPESKVVQNTKAKFDSFGLVLFVIAMVC 212 GG IA Y+ W ++ +I ++ + L+K + K FD G++L + +V Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEV---RIKGHFDIKGIILMSVGIVF 213 Query: 213 LNLIITRGATFGWTSPITITMLVVFLVSAGLFFRVELRQANGFIDFSLFKNKAYTGATLS 272 L +T+ +I+ L+V ++S +F + + + F+D L KN + L Sbjct: 214 FML---------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLC 264 Query: 273 NFLLNAA-AGTLVVANTYVQIGRGFTAFQSGLLSIGYLVCVLGMIR--IGEKILQRVGAR 329 ++ AG + + ++ + + G + I + + +I IG ++ R G Sbjct: 265 GGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVII-FPGTMSVIIFGYIGGILVDRRGPL 323 Query: 330 KPMILGSGITAVGIALMALTFIPGTLYTVLVFIGFALFGIGLGMYATPSTDTAISNAPED 389 + +G +V + +F+ T + I + G GL T + S+ + Sbjct: 324 YVLNIGVTFLSVS--FLTASFLLETTSWFMTIIIVFVLG-GLSFTKTVISTIVSSSLKQQ 380 Query: 390 KVGVASGIYKMASSLGGSFGVAISATI 416 + G + S L G+AI + Sbjct: 381 EAGAGMSLLNFTSFLSEGTGIAIVGGL 407