PredictBias

		>PRTACTNFAMLY#Pertactin virulence factor family signature.

		          Length = 910

		

		 Score = 28.9 bits (64), Expect = 0.032

		 Identities = 31/121 (25%), Positives = 45/121 (37%), Gaps = 19/121 (15%)

		

		Query: 37  GGVFRATEGLQKKYGDQRVWDSPISEGGIAGSAVG-----ASAAGLRPVVEIQFSGFSFP 91

		           GG +RA  GL+ +       +   S  G  G  VG     A    ++P ++       F 

		Sbjct: 795 GGAYRAANGLRVRD------EGGSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQ-EFD 847

		

		Query: 92  AMNQIFTNAARYRTRSHGVYSCPMVVRMPCGGGVKALEHHSEALEAIYSHVPGLKVIMPS 151

		               + TN   +RT   G        R   G G+ A      +L A Y +  G K+ MP 

		Sbjct: 848 GAGTVHTNGIAHRTELRG-------TRAELGLGMAAALGRGHSLYASYEYSKGPKLAMPW 900

		

		Query: 152 T 152

		           T

		Sbjct: 901 T 901

		

		

		>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature.

		          Length = 428

		

		 Score = 29.2 bits (65), Expect = 0.019

		 Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 7/87 (8%)

		

		Query: 1  MKKIKFLLASFATSLAAIPFIAAKCGITDDSKKPTETPAENPALAKVKEAWNNNIKDKIS 60

		          MKK K +L   +   A +P +A  CG  D+S        +   ++K     N N K  + 

		Sbjct: 1  MKKSKKILLGLSPIAAILPAVAVSCGNNDESN----ISFKEKDISKYTTT-NANGKQVVK 55

		

		Query: 61 SAKNYTMILTMLKD--SITDASLKESI 85

		          +A+   +   ++ D   I D S  +S 

		Sbjct: 56 NAELLKLKPVLITDEGKIDDKSFNQSA 82

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score = 80.7 bits (199), Expect = 2e-18

		 Identities = 73/313 (23%), Positives = 119/313 (38%), Gaps = 54/313 (17%)

		

		Query: 13  VNIGTIGHVDHGKTTLTAAIATVLAKKGLSEAKSYDA----IDNAPEEKARGITINTSHI 68

		           +NIG + HVD GKTTLT ++  +     ++E  S D      DN   E+ RGITI T   

		Sbjct: 4   INIGVLAHVDAGKTTLTESL--LYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61

		

		Query: 69  EYNTEKRHYAHVDCPGHADYIKNMITGAAQMDGSILVVAATDGAMPQTKEHVLLAKQVGV 128

		            +  E      +D PGH D++  +    + +DG+IL+++A DG   QT+      +++G+

		Sbjct: 62  SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121

		

		Query: 129 PKMVVFLNKCD----------------------------------MIKPEDAEMIDLVEM 154

		           P  + F+NK D                                  +    ++E  D V  

		Sbjct: 122 PT-IFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIE 180

		

		Query: 155 EVRELLTKYGFDGD-----------NTPFVRGSALQALQGKPEYEENILELMNAVDTWIE 203

		              +LL KY   G            +  F   S      G  +    I  L+  +     

		Sbjct: 181 GNDDLLEKY-MSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFY 239

		

		Query: 204 TPVKDFEKPFLMAVEDVFTISGRGTVATGRVERGRLSLNEEVEIVGLKPTKKT-VVTGIE 262

		           +     +      V  +     R  +A  R+  G L L + V I   +  K T + T I 

		Sbjct: 240 SSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSIN 299

		

		Query: 263 MFRKNLKEAQAGD 275

		                + +A +G+

		Sbjct: 300 GELCKIDKAYSGE 312

		

		

		>cloacin#Cloacin signature.

		          Length = 551

		

		 Score = 33.1 bits (75), Expect = 0.003

		 Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 6/103 (5%)

		

		Query: 97  NNRDGNNGSNN--GNSNNSSNSNGNNGNNINIPGNSNTPT-NSDGRNNNSASGNRDGNNG 153

		           + R  N G+++  GN N      G  G   +  G S+       G  +    G   G +G

		Sbjct: 5   DGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWG---GGSG 61

		

		Query: 154 SNSGDRSSNNGSNSGIDPNKNPYADPFSEKWPADNSSGNNGIS 196

		             +G  + N+G  SG   N +  A P +  +PA ++ G  G++

		Sbjct: 62  HGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLA 104

		

		

		>FbpA_PF05833#Fibronectin-binding protein

		          Length = 577

		

		 Score = 30.6 bits (69), Expect = 0.021

		 Identities = 16/90 (17%), Positives = 32/90 (35%), Gaps = 7/90 (7%)

		

		Query: 369 SRVARRKDKEEKRLTKSISKNKNKLDKTNNKLEN----KLLKTQEKLLKA--KNTKEENK 422

		            R+  +    +K +  +I++   K    NN L+      + K   +LL A     K+   

		Sbjct: 295 DRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTANIYALKKGLS 354

		

		Query: 423 LNKVFDKTKNKLDKTNVKLDNKLNKQE-AQ 451

		             ++ +      D   + LD      +  Q

		Sbjct: 355 HIELANYYSENYDTVKITLDENKTPSQNVQ 384

		

		

		>CHANLCOLICIN#Channel forming colicin signature.

		          Length = 522

		

		 Score = 30.0 bits (67), Expect = 0.027

		 Identities = 23/113 (20%), Positives = 46/113 (40%), Gaps = 2/113 (1%)

		

		Query: 8   AYKNKLEALSRKIDKEVNNVNDIRKEIAKLIEQIQKIKFEIEIKKIENTSSVLTEKLFDE 67

		                +  + + I +  NN N     + +  E ++K +  +   +I++         F +

		Sbjct: 300 RINADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDATVS--FYQ 357

		

		Query: 68  SDADKIKDAERRYAKELADKLKVYNNHRTKSANATVELFSNEWLREIEKAKRD 120

		           +  +K  +   + A+ELADK K         A A  E + +   ++  KA RD

		Sbjct: 358 TLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDVLNKKFSKADRD 410

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 47.8 bits (113), Expect = 1e-07

		 Identities = 45/321 (14%), Positives = 106/321 (33%), Gaps = 17/321 (5%)

		

		Query: 255 KQYEAYISNLKNELETNKKSIEKKIAENKSKLNYLEK---EKLVKAKVELAETKESKKDI 311

		           K   + +S     L+ +   + ++++  K KL   +K   EK  K +   A   + +K +

		Sbjct: 70  KLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKAL 129

		

		Query: 312 LDLLEGAKEEKSNYESEAKIANEEVAKIKVFGDKIDALEKQIKESEAKIEKISSDVKKKD 371

		              +  +  + +  ++         A+       ++          AKI+ + ++    +

		Sbjct: 130 EGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALE 189

		

		Query: 372 VFSQLLKSFYQSSYELKKQIKYLEDRIKDKNSNNFSEEFYFNNEVKFNYELISEWNKAIE 431

		                L+   + +             ++ + +   + +      ++      +  +  I+

		Sbjct: 190 ARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIK 249

		

		Query: 432 RDNEELTELQNEINTFLKVNAKAIEEINKLIDEANKEGHNKDNLASELEKLNEQVKALTK 491

		               E   L+       K    A+        +       K  L +E   L  Q + L  

		Sbjct: 250 TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNA 309

		

		Query: 492 NSKDWRTYLDSKSKEAEKYNDNVATYDKDIEKLNVHMATGEKEEAAGTQVVKEAEEDLAQ 551

		           N +  R  LD+  +                ++L       E++        +    DL  

		Sbjct: 310 NRQSLRRDLDASREA--------------KKQLEAEHQKLEEQNKISEASRQSLRRDLDA 355

		

		Query: 552 LKEEERKLESELAKLLEKEKI 572

		            +E +++LE+E  KL E+ KI

		Sbjct: 356 SREAKKQLEAEHQKLEEQNKI 376

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 28.9 bits (64), Expect = 0.015

		 Identities = 38/189 (20%), Positives = 68/189 (35%), Gaps = 11/189 (5%)

		

		Query: 8    TLPVLFTFPIVSASCTDINQNNSTAENKKPDSNEKIKVDNATTNNANSNENKNDGRSKTE 67

		              PV    P   +  T+    NS  E+K  + NE+   +    N   + E K++ ++ T+

		Sbjct: 1022 EAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQ 1081

		

		Query: 68   QPSKDQAETYSTSNVNKQKEEMLKKLKEELPKLKEKKVELEKTIE------ETKPTEEQL 121

		                 Q+ + +      + +E     KEE     + KVE EKT E      +  P +EQ 

		Sbjct: 1082 TNEVAQSGSETKETQTTETKETATVEKEE-----KAKVETEKTQEVPKVTSQVSPKQEQS 1136

		

		Query: 122  KKAWQDIENKANTSPSEYDESKLKEAYEKWLTVYDKLTNAKNELEILTKSKMIEQTEQAI 181

		            +      E      P+   +    +      T       + N  + +T+S  +      +

		Sbjct: 1137 ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVV 1196

		

		Query: 182  EKLETKLKA 190

		            E  E    A

		Sbjct: 1197 ENPENTTPA 1205

		

		

		>SALVRPPROT#Salmonella virulence-associated 28kDa protein signature.

		          Length = 241

		

		 Score = 28.9 bits (64), Expect = 0.022

		 Identities = 12/25 (48%), Positives = 16/25 (64%)

		

		Query: 79  ELRKGKEDIEAARKALSTRPFYAMM 103

		           ELR G++  E  R+AL   PFY +M

		Sbjct: 215 ELRSGRDGGEMQRQALLEEPFYRLM 239

		

		

		>ACETATEKNASE#Acetate kinase family signature.

		          Length = 400

		

		 Score =  418 bits (1077), Expect = e-148

		 Identities = 185/399 (46%), Positives = 264/399 (66%), Gaps = 8/399 (2%)

		

		Query: 4   KVLVINAGSSSIKLQLLDKEKLNVIASGLAERIGESGNGNIAIKFNGQKFEKSVKLDDHA 63

		           K+LVIN GSSS+K QL++ +  NV+A GLAERIG + +  +    NG+K +    + DH 

		Sbjct: 2   KILVINCGSSSLKYQLIESKDGNVLAKGLAERIGIN-DSLLTHNANGEKIKIKKDMKDHK 60

		

		Query: 64  KAVEYILEIF--EENKIITDPKEIELIGFRVVQGGEYFNSSVKLGDKEIELIDEVKMYAP 121

		            A++ +L+     +  +I D  EI+ +G RVV GGEYF SSV + D  ++ I +    AP

		Sbjct: 61  DAIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAP 120

		

		Query: 122 LHNPGALQAIRAFKKVMPHAKLSADFDTAFHTSIPALYATYPIPYEISEKLKIKRYGAHG 181

		           LHNP  ++ I+A  ++MP   + A FDTAFH ++P     YPIPYE   K KI++YG HG

		Sbjct: 121 LHNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHG 180

		

		Query: 182 ISHEYITLKVQELLNK--EKVNIINLHIGNGASLCAIKESKSIDTTMGLTPLAGIMMGSR 239

		            SH+Y++ +  E+LNK  E + II  H+GNG+S+ A+K  KSIDT+MG TPL G+ MG+R

		Sbjct: 181 TSHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTR 240

		

		Query: 240 SGDIDPSIHQFVMKNMNLSIDEFTDILNKKSGMLGVSGISNDLRDIL-AAMEKGDKRAQF 298

		           SG IDPSI  ++M+  N+S +E  +ILNKKSG+ G+SGIS+D RD+  AA + GDKRAQ 

		Sbjct: 241 SGSIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQL 300

		

		Query: 299 AFDLYCQKIVDFVANYANKLENKIDTIVFTAGVGENTPELREQVVNSLHFTNIKLDKNKN 358

		           A +++  ++   + +YA  +   +D IVFTAG+GEN PE+RE +++ L F   KLDK KN

		Sbjct: 301 ALNVFAYRVKKTIGSYAAAM-GGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKN 359

		

		Query: 359 FGKIGEYELISTPDSDVKVYVIRTNEELLIAKHAIELYK 397

		             + GE  +IST DS V V V+ TNEE +IAK   ++ +

		Sbjct: 360 KVR-GEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIVE 397

		

		

		>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein

		           signature.

		          Length = 166

		

		 Score =  123 bits (310), Expect = 5e-39

		 Identities = 39/137 (28%), Positives = 77/137 (56%), Gaps = 1/137 (0%)

		

		Query: 3   SAIYPGSFDSMHEGHIAIVKKALKIFDKLFVIVSVNPDKESVSDIDKRFVEAKEKLKEFK 62

		           +AIYPGSFD +  GH+ I+++  ++FD+++V V  NP+K+ +  + +R  +  + +    

		Sbjct: 2   NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61

		

		Query: 63  NVEVLINKDGLIAEIAKKLGANFLVRSARNNIDFQYELVLAAGHNSMNKDLETILIMPDY 122

		           N +V    +GL    A++  A  ++R  R   DF+ EL +A  + ++  DLET+ +    

		Sbjct: 62  NAQVDSF-EGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTST 120

		

		Query: 123 DMIEYSSTVIRHKNKLG 139

		           +    SS++++   + G

		Sbjct: 121 EYSFLSSSLVKEVARFG 137

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score =  134 bits (340), Expect = 4e-37

		 Identities = 75/356 (21%), Positives = 143/356 (40%), Gaps = 49/356 (13%)

		

		Query: 7   IGIDLGTTNSVV-----SIVDNGSPVVLENLNGKRTTPSVVSFKDGEIIVGDNAKNQIET 61

		           + IDLGT N+++      IV N   VV    +   +  SV +       VG +AK  +  

		Sbjct: 13  LSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAA-------VGHDAKQMLGR 65

		

		Query: 62  NPDTVASIKRLMGTSKTVHVNNKDYKPEEISAMILEH-LKKYAEEKIGHKVEKAVITVPA 120

		            P  +A+I+ +      V  +        ++  +L+H +K+           + ++ VP 

		Sbjct: 66  TPGNIAAIRPM---KDGVIAD------FFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPV 116

		

		Query: 121 YFDNAQREATKIAGKIAGLEVLRIINEPTAAALAFGLDKVKKEQKILVFDLGGGTFDVSI 180

		                +R A + + + AG   + +I EP AAA+  GL  V +    +V D+GGGT +V++

		Sbjct: 117 GATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGL-PVSEATGSMVVDIGGGTTEVAV 175

		

		Query: 181 LELAEGTFEVLSTAGDNRLGGDDWDNEIVKWLIDLIKKDYKTDVTNNKMAMARLKAAAEK 240

		           + L          +   R+GGD +D  I+      ++++Y              +A AE+

		Sbjct: 176 ISLNGVV-----YSSSVRIGGDRFDEAIIN----YVRRNYG---------SLIGEATAER 217

		

		Query: 241 AKIDLSSS----QQATIMLPFLVMQQGSEPISVEATLR--RSQFEEMTSHLVERCRKPIE 294

		            K ++ S+    +   I +    + +G  P              +E  + +V      +E

		Sbjct: 218 IKHEIGSAYPGDEVREIEVRGRNLAEGV-PRGFTLNSNEILEALQEPLTGIVSAVMVALE 276

		

		Query: 295 TALADAKIKISDLDDVILVGGSTRIPAVQQLVESILNKKANRSVNPDEVVAMGAAI 350

		               +    IS+   ++L GG   +  + +L+          + +P   VA G   

		Sbjct: 277 QCPPELASDISE-RGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGK 331

		

		

		>PF05616#Neisseria meningitidis TspB protein

		          Length = 501

		

		 Score = 34.3 bits (78), Expect = 7e-04

		 Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 4/74 (5%)

		

		Query: 10  GSVASMAAIPFVAAKCGGTKEENKKPAEMPGGTEQPGKPGDTDQPAQPN----PGTTPST 65

		           GS  +  A P            N  P E PG    P    D +  A P+    PGT P +

		Sbjct: 318 GSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDS 377

		

		Query: 66  PAKPGKTPERMAQD 79

		           PA P +   R  ++

		Sbjct: 378 PAVPDRPNGRHRKE 391

		

		

		>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature.

		          Length = 428

		

		 Score = 30.0 bits (67), Expect = 0.014

		 Identities = 28/113 (24%), Positives = 40/113 (35%), Gaps = 15/113 (13%)

		

		Query: 1   MKKSKFVLLGSVASLVSIPFVAAKCGGTKDEEKKPADTQGRGQKNPGDNQNSGTENGGNS 60

		           MKKSK +LLG       +P VA  CG   +      +           N     +N    

		Sbjct: 1   MKKSKKILLGLSPIAAILPAVAVSCGNNDESNISFKEKDISKYTTTNANGKQVVKNAELL 60

		

		Query: 61  NGNSATTNEKKSLSVLISNENQQLGEIKKKD-KDSILDALLAKNKALNLDKSQ 112

		                         VLI++E    G+I  K    S  +AL A NK   ++ + 

		Sbjct: 61  KLK----------PVLITDE----GKIDDKSFNQSAFEALKAINKQTGIEINN 99

		

		

		>PF05616#Neisseria meningitidis TspB protein

		          Length = 501

		

		 Score = 33.2 bits (75), Expect = 9e-04

		 Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 4/74 (5%)

		

		Query: 10  GSVASMAAIPFVAAKCGGTKEENKKPAEMPGGTEQPGKPGDTDQPAQPN----PGTTPST 65

		           GS  +  A P            N  P E PG    P    D +  A P+    PGT P +

		Sbjct: 318 GSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDS 377

		

		Query: 66  PAKPGKTPERMAQD 79

		           PA P +   R  ++

		Sbjct: 378 PAVPDRPNGRHRKE 391

		

		

		>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature.

		          Length = 428

		

		 Score = 33.4 bits (76), Expect = 0.001

		 Identities = 39/172 (22%), Positives = 60/172 (34%), Gaps = 30/172 (17%)

		

		Query: 1   MKKSKFLLLGSLFSLAAIPFVAAKCGGTKEEGNKNPADTQGGGQTDSTPSTSTTVDLSKL 60

		           MKKSK +LLG     A +P VA  C                 G  D +  +    D+SK 

		Sbjct: 1   MKKSKKILLGLSPIAAILPAVAVSC-----------------GNNDESNISFKEKDISKY 43

		

		Query: 61  DQTIQAQLNKLAKDGVKKEEVL---VILKTVEGLKDIKAEDLSTVEFKDK-----KLVIA 112

		             T     N   K  VK  E+L    +L T EG  D K+ + S  E          + I 

		Sbjct: 44  TTT-----NANGKQVVKNAELLKLKPVLITDEGKIDDKSFNQSAFEALKAINKQTGIEIN 98

		

		Query: 113 AKEGSKLVSGKYEFSAQSESDTLMESNKIDLNKLEESVKQELNKLAKNNVLF 164

		             E S      Y  +  +     + +       +++ +     +L +N +  

		Sbjct: 99  NVEPSSNFESAYNSALSAGHKIWVLNGFKHQQSIKQYIDAHREELERNQIKI 150