>SECA#SecA protein signature. Length = 901 Score = 32.5 bits (74), Expect = 0.005 Identities = 22/107 (20%), Positives = 47/107 (43%), Gaps = 15/107 (14%) Query: 419 EKTKLVIVSDDGIGIQKLLFKQCQRYLANGQIEAVFTTEQYQSVYDLLAVDMIVATTDTL 478 EK++ V +++ G+ + L I ++ +S+Y + ++ T L Sbjct: 267 EKSRQVNLTERGL-------VLIEELLVKEGI-----MDEGESLYSPANIMLMHHVTAAL 314 Query: 479 KTKIPMLI-VNPILSDDDIIKLIRFSKQGRLSEHSRFSTELTKAIEA 524 + V+ I+ D ++I + + GR + R+S L +A+EA Sbjct: 315 RAHALFTRDVDYIVKDGEVIIVDEHT--GRTMQGRRWSDGLHQAVEA 359
>PF05043#Transcriptional activator Length = 493 Score = 78.1 bits (192), Expect = 1e-20 Identities = 21/103 (20%), Positives = 46/103 (44%), Gaps = 7/103 (6%) Query: 2 FLTWENLFLT-NQSRRRLKLLVV----ERSYNNVGNFLKEYFGGFFEIVNFDDLRLTMVD 56 ++L + Q++ +LK+LV+ + V L Y FE+ + +L L+ Sbjct: 386 ITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKES 445 Query: 57 MVSLSSEYDVIVTDMILEQTTDSEILFFNQMAPSVVANRLTDM 99 + S YD+I+++ I+ + +++ N + + L M Sbjct: 446 LE--DSPYDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAM 486
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 92.2 bits (229), Expect = 7e-22 Identities = 43/160 (26%), Positives = 65/160 (40%), Gaps = 24/160 (15%) Query: 262 DIDWTQTDDETKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGS 321 + D D Y HG HV G +A +G+APEA ++ ++V G Sbjct: 74 EGDPEIFKD---YNGHGTHVAGTIAAT-----ENENGVVGVAPEADLLIIKVLNKQGSGQ 125 Query: 322 AESLFIKAIEDAVALGADVINLSLGTANGAQLSGSKPLIEAIEKAKKAGVSVVVAAGNER 381 + + I+ I A+ D+I++SLG L EA++KA + + V+ AAGNE Sbjct: 126 YDWI-IQGIYYAIEQKVDIISMSLGGP-----EDVPELHEAVKKAVASQILVMCAAGNEG 179 Query: 382 VYGSDHDDPLATNPDYGLVGSPSTGRTPTSVAAINSKWVI 421 D+ +G P SV AIN Sbjct: 180 DGDDRTDE----------LGYPGCYNEVISVGAINFDRHA 209 Score = 78.7 bits (194), Expect = 2e-17 Identities = 36/147 (24%), Positives = 58/147 (39%), Gaps = 18/147 (12%) Query: 559 FDSVVSKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMAS 618 ++ V+S + FSN + D+ APG DI ST Y + +GTSMA+ Sbjct: 194 YNEVISVGAINFDRHASEFSNSNN------EVDLVAPGEDILSTVPGGKYATFSGTSMAT 247 Query: 619 PQIAGASLLVKQ-YLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGL 677 P +AGA L+KQ + +L + L+ SP+ +G GL Sbjct: 248 PHVAGALALIKQLANASFERDL----TEPELYAQLIKRT-------IPLGNSPKMEGNGL 296 Query: 678 LNIDGAVTSGLYVTGKDNYGSISLGNI 704 L + + G +S ++ Sbjct: 297 LYLTAVEELSRIFDTQRVAGILSTASL 323 Score = 40.2 bits (94), Expect = 4e-05 Identities = 11/34 (32%), Positives = 18/34 (52%), Gaps = 1/34 (2%) Query: 127 HDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS 160 + ++ W++ G+G VAV+DTG D H Sbjct: 26 VEMIQAPAVWNQTR-GRGVKVAVLDTGCDADHPD 58
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 38.5 bits (89), Expect = 2e-05 Identities = 42/170 (24%), Positives = 70/170 (41%), Gaps = 27/170 (15%) Query: 93 INTSLDKAKGELSQLTPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADL 152 IN L + G L+ PEL +V ++ A IP N++VYR G L Sbjct: 295 INNYL-ISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRS--------GPQEFGL 345 Query: 153 TSYYRNHQFDPHILCKIK---------LGTRYTKHSFMSTT--ALKNGAMTHRPVEVRIC 201 T + F+ KI+ G T +F+ST+ ++ A R + +RI Sbjct: 346 TLTSPEYDFN-----KIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRIN 400 Query: 202 VKKGAKAAFVEPYSAVPSEVELLFPRGCQLEV--VGAYVSQDQKKLHIEA 249 + K + A++ E E+L G + ++ V +Y KL ++A Sbjct: 401 IPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDA 450
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.1 bits (62), Expect = 0.039 Identities = 16/61 (26%), Positives = 24/61 (39%), Gaps = 1/61 (1%) Query: 165 KLKDSQTLEKEKKEKERQLAEEKQ-IEEERKHVEQKKLEESMLKQIREEDHKPWHQRLSE 223 + +T E KE EEK +E E+ K + KQ + E +P + E Sbjct: 1089 GSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARE 1148 Query: 224 N 224 N Sbjct: 1149 N 1149
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 99.0 bits (246), Expect = 3e-27 Identities = 67/252 (26%), Positives = 108/252 (42%), Gaps = 24/252 (9%) Query: 3 KVVLVTGCASGIGYAQACYFLKQGHHVYGVDKSDKPDLNGNFHFIKLDLSSELSPL---- 58 K+ +TG A GIG A A QG H+ VD + + +E P Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 59 -----------FEVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVKLTRHY 107 + +DIL N AG+L + +SDEE E F +N +R Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 108 LRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQIHIFGIAP 167 + M++++SG I+ + S + + AY SSK A FT+ L L+ A+ I ++P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 168 GAVKTAM-----TASDFEP---GGLADWVARETPIGRWTEPSEVAELTGFLASGKARSMQ 219 G+ +T M + G + P+ + +PS++A+ FL SG+A + Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 220 GEIVKIDGGWTL 231 + +DGG TL Sbjct: 248 MHNLCVDGGATL 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.8 bits (228), Expect = 1e-23 Identities = 29/133 (21%), Positives = 65/133 (48%), Gaps = 1/133 (0%) Query: 3 KILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLE 62 IL+ DD+ I ++ L++ GYD+ + DL++ D+++P+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 VAKEIRKT-SHVPIIMLSAKDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTET 121 + I+K +P++++SA+++ + E GA DY+ KPF EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 IETAVAEENASSG 134 + + +++ Sbjct: 125 RPSKLEDDSQDGM 137
>PF06580#Sensor histidine kinase Length = 349 Score = 44.1 bits (104), Expect = 7e-07 Identities = 30/187 (16%), Positives = 72/187 (38%), Gaps = 34/187 (18%) Query: 253 DETNRMMRMISDLL--NLSRIDNQVTQLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVY 310 + M+ +S+L+ +L + + LA E+T +++ +F +++ ++ Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQF---EDRLQFENQIN 247 Query: 311 EIVRDYPITSVWIEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQG 370 + D + + ++ ++EN + + I P GGKI ++ + + + + + G Sbjct: 248 PAIMDVQVPPMLVQT-------LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG 300 Query: 371 LGIPKTDLPLIFDRFYRVDKARSRAQGGTGLGLAIAKEIIKQHHGF---IWAKSDYGKGS 427 K + TG GL +E ++ +G I GK Sbjct: 301 SLALKNT------------------KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV- 341 Query: 428 TFTIVLP 434 +++P Sbjct: 342 NAMVLIP 348
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 47.4 bits (112), Expect = 3e-07 Identities = 48/313 (15%), Positives = 95/313 (30%), Gaps = 10/313 (3%) Query: 209 AKVAKQFLELDANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSMEED 268 + VA + + Q + D + + + + + + AL+ + + +E Sbjct: 41 SAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEK 100 Query: 269 YQKFKQKKQVISQESDQTQTTLLELTKLIADLEKQIELVKLESGQ---EAEKKAEAKKHL 325 +K + + + + + +L K + + E A K L Sbjct: 101 LRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL 160 Query: 326 EQLQEQLDGFQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEF 385 E+ E F + + + L L + +L + FS+ ++TL E Sbjct: 161 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 220 Query: 386 VLLMQKEAALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQK 445 L ++A L L + + E L + +L + A A Sbjct: 221 AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 280 Query: 446 EQVEMLLQNYQEGDKRVQELERDYQLNQERLFDLLDQ-------KKGKEARKASLESIQK 498 +++ L + +LE Q+ L KK EA LE K Sbjct: 281 AKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNK 340 Query: 499 SHSQFYAGVRAVL 511 +R L Sbjct: 341 ISEASRQSLRRDL 353
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.3 bits (89), Expect = 4e-05 Identities = 28/141 (19%), Positives = 59/141 (41%), Gaps = 13/141 (9%) Query: 52 SVIGVLFNLFGGVIADSFKR----KKIIITTNILCGTACLVLSFLTKEQWLVYAIVLTNV 107 + G+L +L +I ++ ++ I GT ++L+F T W+ + I+ V Sbjct: 253 AAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT-RGWMAFPIM---V 308 Query: 108 ILAFMSAFSSPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYKLLGIHGV 167 +LA P+ +A V ++ QL L +++ + P++ +Y + Sbjct: 309 LLAS-GGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA----ASI 363 Query: 168 LLLDGLSFLIAALLISFILPV 188 +G +++ A L LP Sbjct: 364 TTWNGWAWIAGAALYLLCLPA 384
>PF05043#Transcriptional activator Length = 493 Score = 28.0 bits (62), Expect = 0.016 Identities = 11/83 (13%), Positives = 30/83 (36%), Gaps = 10/83 (12%) Query: 71 YLTNLPALAHDSLLLSN----VSYQTT-----EALLKLYDQSRSLNKQVFLAFDKASSYS 121 L+++ + D + S+ T + S + F+ F++ Sbjct: 45 DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAE 104 Query: 122 PDANQL-LSENTVLRLSSNGNEL 143 + +S +++ R+ S N++ Sbjct: 105 SICKEFYISSSSLYRIISQINKV 127
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.1 bits (75), Expect = 0.002 Identities = 41/225 (18%), Positives = 86/225 (38%), Gaps = 22/225 (9%) Query: 171 NLYDNIARYKERLKDKSDQLTTFRNARKYAFISNLVGGKKQFEANVSEIKRLEYDLAHLQ 230 ++ + E + S + + A + L + + E + + Sbjct: 225 ARKADLEKALEGAMNFSTADSA-KIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 283 Query: 231 DTHQDKIDSDDIKKNQQKLQLRNTKLELESSLRD------KQRRLKLLDISIEFGLYPTE 284 T + + + + +K + Q + +S RD +++L+ +E +E Sbjct: 284 KTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISE 343 Query: 285 SDLTELQQYFPDTNLKKLYEVEAYHKKLETIL------------DSEFSTE-RESLIAEI 331 + L++ D + + ++EA H+KLE D + S E ++ + + Sbjct: 344 ASRQSLRRDL-DASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKAL 402 Query: 332 DELESQLTTLNQELQELGNIPNLS-SEYLENYSKLTATINALKEQ 375 +E S+L L + +EL L+ E E +KL A ALKE+ Sbjct: 403 EEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEK 447
>PF06580#Sensor histidine kinase Length = 349 Score = 26.0 bits (57), Expect = 0.021 Identities = 7/45 (15%), Positives = 19/45 (42%) Query: 29 LFLAIAIFGMMVTVSYFSYRDARQYYESQITGLRTQLSRTQKQLK 73 + + + M ++ YF + + Y +++I + + QL Sbjct: 120 IIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLM 164
>PRPHPHLPASEC#Prokaryotic zinc-dependent phospholipase C signature. Length = 398 Score = 29.6 bits (66), Expect = 0.016 Identities = 32/180 (17%), Positives = 65/180 (36%), Gaps = 14/180 (7%) Query: 109 NKIRQKEPKSVDDNLKLLVNSFGNELSSYLYGADWSDTKYDLAVEIINKHDVFSGYKQTE 168 N + + EP+SV NL++L +EL D+ YDL + D + + + Sbjct: 52 NDLSKNEPESVRKNLEIL-KENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDN 110 Query: 169 TYKKADKPYDEGELEKNKKLTQLEQLQQLGRLQQL-----EQLQQLGRLQQLEQLQQLGR 223 ++ A D GE + K Q G +Q E + G + + Sbjct: 111 SWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTA 170 Query: 224 LQQLGRLEQLEPTNYSYEAFSDIEDAIFYLDPPYENTTQKSYKGDFNSQAFYDWAFGMSK 283 + G ++ +E F++ + ++ T + Y ++ F W+ ++ Sbjct: 171 VDSAGHVK--------FETFAEERKEQYKINTAGCKTNEDFYADILKNKDFNAWSKEYAR 222
>SSPAMPROTEIN#Salmonella surface presentation of antigen gene type M signature. Length = 147 Score = 28.9 bits (64), Expect = 0.036 Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 6/65 (9%) Query: 387 ERINALENNQKVITNNQKQFELNLPKYLNDINGKRVWYEKPDDNIEHKIGDYWFEKNGKY 446 E I AL Q ++ K EL + + I KR EK + + K YW K G Y Sbjct: 66 EEIYALLRKQSIVRRQIKDLELQIIQ----IQEKRSELEKKREEFQEK-SKYWLRKEGNY 120 Query: 447 QRTWI 451 QR WI Sbjct: 121 QR-WI 124
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 563 bits (1452), Expect = 0.0 Identities = 336/336 (100%), Positives = 336/336 (100%) Query: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL 60 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL Sbjct: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL 60 Query: 61 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI 120 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI Sbjct: 61 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI 120 Query: 121 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA 180 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA Sbjct: 121 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA 180 Query: 181 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA 240 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA Sbjct: 181 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA 240 Query: 241 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQID 300 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQID Sbjct: 241 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQID 300 Query: 301 GNLKLKNPTADDHAATKAYVDSEVKKLKALLMDKQV 336 GNLKLKNPTADDHAATKAYVDSEVKKLKALLMDKQV Sbjct: 301 GNLKLKNPTADDHAATKAYVDSEVKKLKALLMDKQV 336
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.6 bits (77), Expect = 0.003 Identities = 27/145 (18%), Positives = 51/145 (35%), Gaps = 21/145 (14%) Query: 158 RLSSSYQSGINGLKAQLANDKI---GLQAEIQATAQGLSQKYDNELRQLSAKITTTSSGT 214 RL+S + + + Q ++ +AE T +Y+N R +++ SS Sbjct: 186 RLTSLIKEQFSTWQNQKYQKELNLDKKRAERL-TVLARINRYENLSRVEKSRLDDFSSLL 244 Query: 215 TEAYESKLAGLRAEFTRSNQGMRIELESQISGLRAVQQSTASQISQEIRDRTGAVSRVQQ 274 + +K A L E E++ + SQ+ Q + A Q Sbjct: 245 HKQAIAKHAVL-------------EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL 291 Query: 275 DLESYQR----RLQDAEDNYSSLTH 295 + ++ +L+ DN LT Sbjct: 292 VTQLFKNEILDKLRQTTDNIGLLTL 316
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 30.9 bits (70), Expect = 0.004 Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 1/76 (1%) Query: 37 SYQDFLDVLLSLFQFVVIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIE 96 S + ++ L S+ + V++ ++++ NL +L T L +L + +I Sbjct: 133 SIKSLVEFLKSILKVVLLSILIWII-IKGNLVTLLQLPTCGIECITPLLGQILRQLMVIC 191 Query: 97 MTLLVLILIFDVLLQK 112 V+I I D + Sbjct: 192 TVGFVVISIADYAFEY 207
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.4 bits (105), Expect = 6e-07 Identities = 21/112 (18%), Positives = 45/112 (40%), Gaps = 13/112 (11%) Query: 170 QQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVE-----VNNDIDPSSKNSQTLV 224 +L+ D E+ K + +V+ + VS V + + ++TL+ Sbjct: 302 DKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT----AETLM 357 Query: 225 HVATEGQ-LQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEW---TGKISYVS 272 + E L+V + D+ + VGQ+ IK + + + GK+ ++ Sbjct: 358 VIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN 409 Score = 37.5 bits (87), Expect = 8e-05 Identities = 24/185 (12%), Positives = 55/185 (29%), Gaps = 29/185 (15%) Query: 21 ITLVLIITGVVLWKQQQNTLTADIDKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFD 80 ++ + + ++ ++ V+ G + S S +K + + Sbjct: 62 YFIMGFLVIAFIL-----SVLGQVEI-----VATANGKLTHSGR-SKEIKPIENSIV--- 107 Query: 81 ANKGNDATVTVKVGDQVTQGQQLVQYNTTTA-------QSAYDTAVRSLNKIGRQINHLK 133 + VK G+ V +G L++ A QS+ A + ++ Sbjct: 108 ------KEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIE 161 Query: 134 TYGVPAV--STETNKDEATGEETTTTVQPSAQQNANYKQQLQDLNDAYADAQAEVNKAQI 191 +P + E + EE +Q + ++ Q +AE Sbjct: 162 LNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLA 221 Query: 192 ALNDT 196 +N Sbjct: 222 RINRY 226
>SECA#SecA protein signature. Length = 901 Score = 29.5 bits (66), Expect = 0.028 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Query: 165 VIKH-YEKLAKGKQAIVYTHSVEASHLVSDTFNQAGYQSQSVSGKTSKSEREEAMQAFRD 223 +I+ E+ AKG+ +V T S+E S LVS+ +AG + ++ K +E QA Sbjct: 438 IIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYP 497 Query: 224 GKLRILVN 231 + I N Sbjct: 498 AAVTIATN 505
>PF05272#Virulence-associated E family protein Length = 892 Score = 25.4 bits (55), Expect = 0.046 Identities = 14/55 (25%), Positives = 19/55 (34%), Gaps = 4/55 (7%) Query: 10 TPQKTGKKDKLGNDITKDVVKRDAKGRFTEWSADDVSLYGRDLTSSARKLLTNQV 64 P+K G D D + F EW D+V+ L R LL + Sbjct: 402 PPKKRDPSAGAGTDPGGPGGGDDGEDPFGEWLDDEVA----RLRLRGRWLLKPRR 452
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 39.3 bits (91), Expect = 6e-05 Identities = 32/139 (23%), Positives = 56/139 (40%), Gaps = 9/139 (6%) Query: 294 VFSQLYLESFWGDTPVGRAD----NNWGGI----TWTGATTRPSGINVSQGQPRAEGGHY 345 + +Q LES WG + R + N G+ W G T + G+ + + Sbjct: 174 ILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKF 233 Query: 346 NHYASVDDYLKDYTYLLAEQGIY-AVKGKLTIDEYTRGLFRVGGATYDYAAAGYDHYAPL 404 Y+S + L DY LL Y AV + ++ + L G AT + A + Sbjct: 234 RVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQ 293 Query: 405 MRDIRAGINRNNNGAMDNV 423 M+ I +++ + +DN+ Sbjct: 294 MKSISDKVSKTYSMNIDNL 312
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 25.9 bits (57), Expect = 0.007 Identities = 13/41 (31%), Positives = 18/41 (43%), Gaps = 14/41 (34%) Query: 25 EFGWITLEDVPKKYR--------------DKVKQLVESGNI 51 E GWI ED + +R + +K+LVE G I Sbjct: 148 EKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLVERGVI 188
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 28.9 bits (64), Expect = 0.004 Identities = 15/63 (23%), Positives = 25/63 (39%), Gaps = 5/63 (7%) Query: 25 VSAPVKHVLDNNKKAMEALESAIVKISDD-----LKDNNFKWTESKNHRDRLQKVQDQHE 79 + APV +D + L + + +SD LKDN F + R + D Sbjct: 38 IDAPVTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNEN 97 Query: 80 IRI 82 +R+ Sbjct: 98 VRL 100
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 27.8 bits (62), Expect = 0.009 Identities = 11/54 (20%), Positives = 21/54 (38%), Gaps = 5/54 (9%) Query: 46 VARNAVEAVEQIAYDKDIK---GIEKLTEAKIAVRDELSKHNVYLSDK--QMEV 94 ++V V Q + D + G+ K A R + K ++ + +EV Sbjct: 486 RTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEV 539
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 27.5 bits (61), Expect = 0.008 Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 5/44 (11%) Query: 7 RMILMFDMPTDTAEE-----RKAYRKFRKFLLSEGFIMHQFSIY 45 R + FD+ T + E+ R+ Y +KF+L GF Q+S Y Sbjct: 5 RKAINFDLSTKSLEKYFKDTREPYSLIKKFMLENGFEHRQYSGY 48
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 112 bits (282), Expect = 3e-28 Identities = 51/156 (32%), Positives = 81/156 (51%), Gaps = 8/156 (5%) Query: 12 KIRNFSIIAHIDHGKSTLADRILEK---TETVSSREMQAQLLDSMDLERERGITIKLNAI 68 KI N ++AH+D GK+TL + +L + S + D+ LER+RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 ELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLA 128 + E ++IDTPGH+DF EV RSL+ +GAIL++ A G++AQT + Sbjct: 62 SFQW-----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 129 LDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDA 164 + + INKID D V ++++ + + Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEI 152 Score = 91.5 bits (227), Expect = 2e-21 Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 16/214 (7%) Query: 171 SAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKSGD 230 SAK IGI+ ++E I K + T + L +F Y R + +R+ +G++ D Sbjct: 220 SAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRD 279 Query: 231 KIQMMSNGKTFDVTEVGIFTP-KAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNP 289 +++ K +TE+ + D +G++ + + +GDT L Sbjct: 280 SVRISEKEKI-KITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQRE 337 Query: 290 AKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFE--PETSQALGFGF 347 E P++ + P + + L +AL ++ +D L++ T + + Sbjct: 338 RIENPL------PLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEII---- 387 Query: 348 RCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVY 381 FLG + M+V L+ ++++++ + P+V+Y Sbjct: 388 -LSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIY 420 Score = 43.3 bits (102), Expect = 2e-06 Identities = 21/104 (20%), Positives = 41/104 (39%), Gaps = 12/104 (11%) Query: 393 VSNPSEFPDPTRVAFIE----------EPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMD 442 VS P++F + + EPY+ +I PQE++ + + + V Sbjct: 510 VSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ 569 Query: 443 YIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYR 486 + +N V + +IP I ++ L T G + ++ Y Sbjct: 570 -LKNNEVILSGEIPARCI-QEYRSDLTFFTNGRSVCLTELKGYH 611
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 71.6 bits (175), Expect = 2e-15 Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 12/105 (11%) Query: 378 QPGKPAPKTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAK 437 + K A + ++ + TP P + +G NQ Sbjct: 447 KLAKQAEELAKLRAGKASDSQTPDAK----------PGNKAVPGKGQAPQAGTKPNQ--N 494 Query: 438 TPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN 482 +T RQLP+TGET NPFFTAAA+ +M TAGV AV KR+E N Sbjct: 495 KAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN 539
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-17 Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Query: 3 KILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFKGYDLILLDIMMPNISGTE 62 IL DDD I ++ AL Y V + DL++ D++MP+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 FCYKIREE-VHSPIIFVSALDGDNEIVQALNIGGDDFIVKPFSLKQFVAKVNSHLKREER 121 +I++ P++ +SA + ++A G D++ KPF L + + + L +R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 AKIKNEAEER 131 K E + + Sbjct: 125 RPSKLEDDSQ 134
>NISIN#Nisin signature. Length = 57 Score = 26.7 bits (58), Expect = 0.001 Identities = 17/32 (53%), Positives = 23/32 (71%), Gaps = 2/32 (6%) Query: 4 TIKDFDLDL-KTNKKDT-ATPYVGSRYLCTPG 33 + KDF+LDL +KKD+ A+P + S LCTPG Sbjct: 2 STKDFNLDLVSVSKKDSGASPRITSISLCTPG 33
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 30.1 bits (67), Expect = 0.010 Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 7/47 (14%) Query: 184 NKWYLFPYDWSLKLLEPMTRMGINSIPFGAEFVPDYSQIFISLFLGI 230 NK Y+ +W+ +P+T+ IN+IP AEF+ + S I S +G+ Sbjct: 639 NKAYI---EWT----DPITKAKINTIPTSAEFIKNLSSIRRSSNVGV 678
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 36.6 bits (84), Expect = 1e-04 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 31 SGSQSDKLVIYNWGDYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVP 90 S S V+ N+ YI P LL++ + + + T+ SNE + TY +AV Sbjct: 21 SSCGSTTFVLANFESYISPLLLER--VQEKHPLTFLTYPSNEKLINGF--ANNTYSVAVA 76 Query: 91 SDYTIDKMIKENLLNKLDKSKL 112 S Y + ++I+ +LL+ +D S+ Sbjct: 77 STYAVSELIERDLLSPIDWSQF 98
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.2 bits (164), Expect = 3e-15 Identities = 23/131 (17%), Positives = 50/131 (38%), Gaps = 2/131 (1%) Query: 3 VLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTDYAIDLILLDIHITDGNGI 62 +L+ +DD + + L + + + + + + DL++ D+ + D N Sbjct: 6 ILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 QFLEKWRAQHIPCEVIIISAANDGNIIRDGFHLGIIDYLIKPFTFERFQESIQQFVTHRE 122 L + + V+++SA N G DYL KPF I + + + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 123 HLANQQLEQAQ 133 ++ + +Q Sbjct: 124 RRPSKLEDDSQ 134
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 32.0 bits (73), Expect = 0.002 Identities = 14/75 (18%), Positives = 27/75 (36%), Gaps = 8/75 (10%) Query: 172 TIGILERIVIGVCMIMG---QFASIGLVFTAKSIA-RYNKISESPAFAEYYLIGSLF--- 224 L ++ V +M G + + ++I KI+ + I SL Sbjct: 82 EFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKINPIEGAKRIFSIKSLVEFL 141 Query: 225 -SILSVFIAAWICFF 238 SIL V + + + + Sbjct: 142 KSILKVVLLSILIWI 156
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.024 Identities = 8/28 (28%), Positives = 14/28 (50%) Query: 87 EILAPADGLVSKIHVVANQTVESEQVLI 114 EI + +V +I V ++V VL+ Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLL 125 Score = 26.3 bits (58), Expect = 0.029 Identities = 13/40 (32%), Positives = 22/40 (55%) Query: 51 VKAPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILA 90 +K + V I EG++V+KG+ +L L A+ E + L Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.004 Identities = 10/49 (20%), Positives = 22/49 (44%) Query: 87 AIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEIVASSAGTITA 135 I + +++V G+ V + LL L A+ E + + + + + A Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQA 146 Score = 27.1 bits (60), Expect = 0.035 Identities = 9/30 (30%), Positives = 13/30 (43%) Query: 124 EIVASSAGTITAIHVGPGQVVNPGDGLITI 153 EI + I V G+ V GD L+ + Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKL 127
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 65.8 bits (160), Expect = 4e-14 Identities = 76/299 (25%), Positives = 120/299 (40%), Gaps = 45/299 (15%) Query: 36 DLKVAMVTDTGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAV 95 LK ++TD G +DDKSFNQSA+E L++ + K TG + S + + ++A+ Sbjct: 61 KLKPVLITDEGKIDDKSFNQSAFEALKA------INKQTGIEINNVEPSSNFESAYNSAL 114 Query: 96 SGGYQLIYGIGFALKDAIAKAAGD------NEGVKFVIIDDIIEGKDNV-ASVTFADHEA 148 S G+++ GF + +I + +K + ID IE + S+ F E+ Sbjct: 115 SAGHKIWVLNGFKHQQSIKQYIDAHREELERNQIKIIGIDFDIETEYKWFYSLQFNIKES 174 Query: 149 AYLAGIAAAKTTKTK-----TVGFVGGMEGTVITRFEKGFEAGVKS---------VDDTI 194 A+ G A A + V GG +T F +GF G+ + T Sbjct: 175 AFTTGYAIASWLSEQDESKRVVASFGGGAFPGVTTFNEGFAKGILYYNQKHKSSKIYHTS 234 Query: 195 QVKVDYAGSFGDAAKGKTIAAAQYAAGADVIYQAAGG---TGAGVFNEAKAINEKRSEAD 251 VK+D +G I + ADV Y G F + N+ + Sbjct: 235 PVKLD-SGFTAGEKMNTVINNVLSSTPADVKYNPHVILSVAGPATFETVRLANKGQ---- 289 Query: 252 KVWVIGVDRDQKDEGKYTSKDGKEANFVLASSIKEVGKAVQLINKQVADKKFPGGKTTV 310 +VIGVD DQ +D +L S +K + +AV + +K G K V Sbjct: 290 --YVIGVDSDQG-----MIQDKDR---ILTSVLKHIKQAVYETLLDLILEKEEGYKPYV 338
>PF06580#Sensor histidine kinase Length = 349 Score = 39.1 bits (91), Expect = 2e-05 Identities = 15/75 (20%), Positives = 31/75 (41%), Gaps = 5/75 (6%) Query: 312 YGKIFYFQNQVNRSLRMDKALLKQLITILFDNAIKY----TDKNGIIEIIVKTTDKNLLI 367 + F+NQ+N ++ D + L+ L +N IK+ + G I + + + + Sbjct: 236 FEDRLQFENQINPAIM-DVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTL 294 Query: 368 SVIDNGPGITDEEKK 382 V + G K+ Sbjct: 295 EVENTGSLALKNTKE 309
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.5 bits (76), Expect = 8e-04 Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Query: 36 KGELVVIL-GASGAGKSTVLNILGGMD-TVDAGQVIIDGKD 74 K + V+L G G GKST++N L G+D D I GKD Sbjct: 594 KFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 41.2 bits (96), Expect = 5e-07 Identities = 13/48 (27%), Positives = 25/48 (52%) Query: 4 RHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTFYLHYTDK 51 ET+ ++ L ++Q + ++ ++ K AG+ RG Y H+ DK Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDK 55
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 151 bits (383), Expect = 1e-49 Identities = 49/154 (31%), Positives = 85/154 (55%), Gaps = 4/154 (2%) Query: 19 KKEASKNEKT--KAVLNQAVADLSVAASIVHQVHWYMRGPGFLYLHPKMDELLDSLNANL 76 K E +K +T + LN +++ + S +H+ HWY++GP F LH K +EL D + Sbjct: 2 KTENAKTNQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETV 61 Query: 77 DEMSERLITIGGAPYSTLAEFSKHSKLDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGL 136 D ++ERL+ IGG P +T+ E+++H+ + + + + ++ + LV Y +SS + + Sbjct: 62 DTIAERLLAIGGQPVATVKEYTEHASITDGGN--ETSASEMVQALVNDYKQISSESKFVI 119 Query: 137 DITDEEGDAGTNDLFTAAKTEAEKTIWMLQAERG 170 + +E D T DLF E EK +WML + G Sbjct: 120 GLAEENQDNATADLFVGLIEEVEKQVWMLSSYLG 153
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 29.4 bits (66), Expect = 0.009 Identities = 42/160 (26%), Positives = 59/160 (36%), Gaps = 25/160 (15%) Query: 70 SLIIILWASMVHWVSASYCYLLLFSLLFSLF--DWRSQ------EYPFILWLFSFVSLLL 121 +L+ + A + + LLL +L +L D P + F L Sbjct: 118 ALLSVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGG 177 Query: 122 FYSIN---------YLSLILLLLGLLAHLRPFSIGAGDFFYLASLALVLDLTSLIWLIQL 172 F S+ YL L L +G GDF LA+L L +L ++ L Sbjct: 178 FVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLL 237 Query: 173 ASLAGITACLLL-------GIKRIPFIPYLSFGLFWIVLL 205 +SL G + L K IPF PYL+ WI LL Sbjct: 238 SSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIA-GWIALL 276
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 33.4 bits (76), Expect = 7e-04 Identities = 9/34 (26%), Positives = 19/34 (55%) Query: 8 KLILQGGKAMVTIKQVAEEAGVSRSTVSRYISQK 41 +L Q G + ++ ++A+ AGV+R + + K Sbjct: 22 RLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDK 55
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 153 bits (389), Expect = 2e-50 Identities = 58/157 (36%), Positives = 94/157 (59%), Gaps = 2/157 (1%) Query: 5 IGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKKSYFKLEVRKAMLTQALADFT 64 +Y GSFDP+T GHLDI++R LFDQ+YV + NP K+ F ++ R + +A+A Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 65 NVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEENLEYFNHLLAPNIETVYLISRN 124 N V + E L ++ A++ + ++RGLR +DFE E + N LA ++ETV+L + Sbjct: 62 NAQVDSF-EGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTST 120 Query: 125 KWQALSSSRVRELIHFQSSLEDLVPQSVIAQV-EKMN 160 ++ LSSS V+E+ F ++E VP V A + ++ + Sbjct: 121 EYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFH 157
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 405 bits (1043), Expect = e-145 Identities = 141/315 (44%), Positives = 204/315 (64%), Gaps = 6/315 (1%) Query: 3 KQKIVVALGGNAIL--STDASAKAQQEALISTSKSLVKLIKEGHEVIVTHGNGPQVGNLL 60 +++V+ALGGNA+ S + + + T++ + ++I G+EV++THGNGPQVG+LL Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61 Query: 61 LQQAAADSEKN-PAMPLDTCVAMTEGSIGFWLVNALDNELQAQGIQKEVAAVVTQVIVDA 119 L A + PA P+D AM++G IG+ + AL NEL+ +G++K+V ++TQ IVD Sbjct: 62 LHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDK 121 Query: 120 KDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWRKVVPSPKPVGIKEANVIRS 179 DPAF+NPTKP+GPF EE AK+ E G KED+GRGWR+VVPSP P G EA I+ Sbjct: 122 NDPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKK 181 Query: 180 LVDSGVVVVSAGGGGVPVVEDATSKTLTGVEAVIDKDFASQTLSELVDADLFIVLTGVDN 239 LV+ GV+V+++GGGGVPV+ + + GVEAVIDKD A + L+E V+AD+F++LT V+ Sbjct: 182 LVERGVIVIASGGGGVPVILED--GEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNG 239 Query: 240 VYVNFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLPKVEAAIAFVENKPNAKAIITSLE 299 + + + L EV V ++++Y + F GSM PKV AAI F+E +AII LE Sbjct: 240 AALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEW-GGERAIIAHLE 298 Query: 300 NIDNVLSANAGTQII 314 L GTQ++ Sbjct: 299 KAVEALEGKTGTQVL 313
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 577 bits (1490), Expect = 0.0 Identities = 191/410 (46%), Positives = 276/410 (67%), Gaps = 9/410 (2%) Query: 5 TPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDE 64 PI+++SEIG+LKKVLLHRPG+E+ENL P ++ LFDDIP+LE A++EH+ FA L++ Sbjct: 6 NPINIFSEIGRLKKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQEHEVFASILKNN 65 Query: 65 GIEVLYLETLAAESLVTP-EIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEK 123 +E+ Y+E L +E LV+ + FI +++ EA I+ T +++ ++ +I K Sbjct: 66 LVEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINLLKDYFSSL-TIDNMISK 124 Query: 124 TMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSE 183 ++GV EL +S L DLV F IDPMPN+ FTRDPFA+IG GV++N MF++ Sbjct: 125 MISGVVTEELKNYTSS---LDDLVNGANLFIIDPMPNVLFTRDPFASIGNGVTINKMFTK 181 Query: 184 TRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAA 243 R RET++ +YIF +HP+Y VP+ +R E +EGGDELVL+K +L +GIS+RT+A Sbjct: 182 VRQRETIFAEYIFKYHPVYKE-NVPIWLNRWEEASLEGGDELVLNKGLLVIGISERTEAK 240 Query: 244 SIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSV 303 S+EKL +++FK F +LAF+ NR +MHLDTVFT +DY FT + +Y + Sbjct: 241 SVEKLAISLFKNKTSFDTILAFQIPKNRSYMHLDTVFTQIDYSVFTSFTSDDMYFSIYVL 300 Query: 304 TYDNE--ELHIIEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAP 361 TY+ ++HI +EK + ++L+ LG K+D+I+C G +L+ REQWNDG+N L IAP Sbjct: 301 TYNPSSSKIHIKKEKARIKDVLSFYLG-RKIDIIKCAGGDLIHGAREQWNDGANVLAIAP 359 Query: 362 GVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI 411 G ++ Y+RN +TN + E G+K+ +I SEL RGRGGPRCMSMP REDI Sbjct: 360 GEIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGPRCMSMPLIREDI 409
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 124 bits (314), Expect = 2e-39 Identities = 61/146 (41%), Positives = 92/146 (63%), Gaps = 2/146 (1%) Query: 1 MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDT 60 MNK + RH IR +I+ I TQ EL + L+K+G +TQAT+SRD+KEL+LVKV + N + Sbjct: 1 MNKGQ-RHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGS 59 Query: 61 HYEALAISQTRWEH-RLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIV 119 + +L Q +L+ + DA V + H I+LKT+PG AQ+ G+++D + EI+ Sbjct: 60 YKYSLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEEIM 119 Query: 120 ATICGDDTCLIVCEDNEQAKACYETL 145 TICGDDT LI+C ++ K + + Sbjct: 120 GTICGDDTILIICRTHDDTKVVQKKI 145
>PF06580#Sensor histidine kinase Length = 349 Score = 181 bits (462), Expect = 2e-54 Identities = 57/203 (28%), Positives = 100/203 (49%), Gaps = 10/203 (4%) Query: 362 EKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGN- 420 + +L AL +QINPHF++N L+ I + D + E+ SL++ R +L N Sbjct: 155 ASMAQEAQLMALKAQINPHFMFNALNNIRALIL-EDPTKAREMLTSLSELMRYSLRYSNA 213 Query: 421 EYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIK 480 + LADEL V YL + ++ D+L +E Q D +P +++Q LVEN I HGI Sbjct: 214 RQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA 273 Query: 481 EVDRKGMIKVTVSDTAQHLVLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHY 540 ++ + G I + + + L V + G ++ ++ G GL+NV +RL++ Y Sbjct: 274 QLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKEST-------GTGLQNVRERLQMLY 326 Query: 541 GKGYHMTIHSQSDHFTEIQLSLP 563 G + + + + + +P Sbjct: 327 GTEAQIKLSEKQGKVNAM-VLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.4 bits (232), Expect = 5e-24 Identities = 41/165 (24%), Positives = 74/165 (44%), Gaps = 12/165 (7%) Query: 3 SLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLN 62 ++L+ +D+ +R + + + + V N W D+V+TD+ MP N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY---DVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GIQLAELIKQESPQTHLVFLTGYDDFNYALSALRLGADDYLLKPFSKADVEDMLGKLRKK 122 L IK+ P ++ ++ + F A+ A GA DYL KPF D+ +++G + + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF---DLTELIGIIGRA 118 Query: 123 LELSKKTETIQELVEQPQKEVSAIAMAIHE------QLADSDLTL 161 L K+ + E Q + + A+ E +L +DLTL Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 45.7 bits (108), Expect = 5e-08 Identities = 44/222 (19%), Positives = 85/222 (38%), Gaps = 36/222 (16%) Query: 61 LKEIYN-KEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKKVISSNLSPSQERMFNV 119 +K +Y+ + S++ LI+N + D KV + L+ + + Sbjct: 51 MKYLYDDHYVSATKVKSVDKFLAHDLIYNISDKKLKNYD----KVKTELLNEDLAKKYK- 105 Query: 120 GDHVNIFAIVKSYHVVCKEQFNYSD---------GGIIKTSDVKPEE---KAIYINIFGE 167 + V+++ + + N GGI K + + + + ++ Sbjct: 106 DEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYEN 165 Query: 168 KELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYD-SLYKKGFWDIHYKDG 226 K T ++ VT QE+D++ R L+ +K LYE++ S Y+ G+ +G Sbjct: 166 KRN---TISFEVQTDKKSVTAQELDIKARNFLI--NKKNLYEFNSSPYETGYIKFIENNG 220 Query: 227 GIRHTNLFTYPD-----------YTDNETIDMSKVSHFDVHL 257 ++ P Y DN+T+D SK +VHL Sbjct: 221 NTFWYDMMPAPGDKFDQSKYLMMYNDNKTVD-SKSVKIEVHL 261
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 96.7 bits (240), Expect = 6e-25 Identities = 46/123 (37%), Positives = 65/123 (52%), Gaps = 8/123 (6%) Query: 23 SLTAAQAILESGWGKHA-------PHNALFGIKADASWTGKSFNTKTQEEYQAGVITDIV 75 L AQA LESGWG+ P LFG+KA +W G T E Y+ G + Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230 Query: 76 DRFRAYDSWDESIADHGQFLVDNPRYQSVIGEADYKKACHAIKDAGYATASGYAELLIQI 135 +FR Y S+ E+++D+ L NPRY +V A ++ A++DAGYAT YA L + Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290 Query: 136 IEE 138 I++ Sbjct: 291 IQQ 293
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 28.5 bits (63), Expect = 0.003 Identities = 12/29 (41%), Positives = 16/29 (55%) Query: 1 MWLADSSVEDSAEVSCCTVHGVISYRGLK 29 MWL+ ++ E+ HGVIS GLK Sbjct: 206 MWLSKVVDDEGKEIFSGIRHGVISAYGLK 234
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 27.8 bits (61), Expect = 0.026 Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Query: 71 QAEAKVEKYKETIRRAMELSQKKKVDAGMFKVSLRKSKKVEILDETKIPLDYMQEKIEYK 130 + A E Y E+ + ++K K + FK S+ K E +ET + Q+ ++ Sbjct: 30 EVNAMNEHYTESDIKRNHKTEKNKTEKEKFKDSINNLVKTEFTNETLDKIQQTQDLLKKI 89 Query: 131 PMKS-EISKALKSGIDISGVELIETESLQ 158 P EI L I + ++L+E + LQ Sbjct: 90 PKDVLEIYSELGGEIYFTDIDLVEHKELQ 118
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 32.4 bits (74), Expect = 0.006 Identities = 19/88 (21%), Positives = 33/88 (37%), Gaps = 5/88 (5%) Query: 290 FEAVILAIPLLLIQLIAFLADIVVILLMFLFPLALLVSFLPKMQHIAFNM-LKLMLG--- 345 F A+ A L+ + + ++ +LL L LL P++ L L +G Sbjct: 169 FLALTKAGSLIFLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISL 228 Query: 346 -GVSFPALTGFLTLIVFYIQSLIATFIK 372 P + F + I +L+A I Sbjct: 229 MAALMPLIAPFCEHLFSEIFNLLADIIS 256 Score = 31.3 bits (71), Expect = 0.012 Identities = 22/144 (15%), Positives = 51/144 (35%), Gaps = 16/144 (11%) Query: 267 QNRWMSAVSDYIWIKSIYVILKIFEAVILAIPLLLIQLIAFLADIVVILLMFLFPLALLV 326 +W+S ++ Y W +L++ A+I P+L + + + + +++ L Sbjct: 6 SEQWLSWLNLYFW-----PLLRVL-ALISTAPILSERSVPKRVKLGLAMMITFAIAPSLP 59 Query: 327 SFLPKMQHIAFNMLKLMLGGVSFPALTGFLTLIVFYIQSLIATFIK-------SRFTDNH 379 + + +F L L + + GF F I + F D Sbjct: 60 ANDVPV--FSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPA 117 Query: 380 LLSSSNLKGQSILFMLFITIVVQG 403 + + + I+ ML + + + Sbjct: 118 SHLNMPVLAR-IMDMLALLLFLTF 140
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 26.3 bits (58), Expect = 0.015 Identities = 10/73 (13%), Positives = 26/73 (35%), Gaps = 11/73 (15%) Query: 18 VSGLKQFFQGDGIY----------LISVICAFLVIKNWKNADWLKVGSVLSIYAIVVSLF 67 + G K+ F + L+S++ ++ N L + I ++ + Sbjct: 125 IEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQIL 184 Query: 68 KGQEILAFLGGML 80 + Q ++ G + Sbjct: 185 R-QLMVICTVGFV 196
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 26.9 bits (59), Expect = 0.009 Identities = 10/27 (37%), Positives = 13/27 (48%) Query: 39 FNELGSEGVGKENMELYFDCEAYGRDI 65 EL +GV E L+ AYGR + Sbjct: 325 LKELQRKGVSNEAPPLFVSNVAYGRTV 351
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 65.1 bits (158), Expect = 1e-12 Identities = 76/384 (19%), Positives = 158/384 (41%), Gaps = 44/384 (11%) Query: 106 THDSLSSAQADLEKQTQAVTEATTKQEANTTAINQAVSENKAIDQANRDEKARVDALNTK 165 + +L +L ++ E K N ++++ S+ + ++ D + ++ Sbjct: 79 NNKALKDHNDELTEELSNAKE---KLRKNDKSLSEKASKIQELEARKADLEKALEGAMNF 135 Query: 166 GEADTKAKN--ETGQAQVDAQNKQAQAAADAMNAKLKADYEAKLTEIKQIESENEAIRQR 223 AD+ E +A + A+ + A + AD AK+ ++ ++ EA + Sbjct: 136 STADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTAD-SAKIKTLEAEKAALEARQAE 194 Query: 224 NQQASQATHQANQAAQAAYQEKLAEIERIKAENAAIRDRNAKAQQEAERQNQALQAAYEA 283 ++A + + A A + AE + A A + KA + A + A A + Sbjct: 195 LEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL----EKALEGAMNFSTADSAKIKT 250 Query: 284 KLAEIKQIESENAAIRQRNEQAGQATNQTNQAAQAAYQEKLAEIERIKAGNAAIRDRNAK 343 AE +E+ A + + E A + A A + AE ++A A + ++ Sbjct: 251 LEAEKAALEARQAELEKALEGA----MNFSTADSAKIKTLEAEKAALEAEKADLEHQSQV 306 Query: 344 AQQEAERQNQALQAAYEAKLAEIKQIESENAAIRKRN---EQAGQTTNQTNQAAQAAYQE 400 + + L A+ EAK KQ+E+E+ + ++N E + Q+ + A++ A ++ Sbjct: 307 LNANRQSLRRDLDASREAK----KQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ 362 Query: 401 KLAEIERINAENAAIR------DRNTKARQEAERQNQQLKTTYEAQLSAYQQA------- 447 AE +++ +N R+ A +EA++Q ++ ++L+A ++ Sbjct: 363 LEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEES 422 Query: 448 ----------LQAKKEAENKAIDQ 461 LQAK EAE KA+ + Sbjct: 423 KKLTEKEKAELQAKLEAEAKALKE 446 Score = 58.9 bits (142), Expect = 9e-11 Identities = 61/346 (17%), Positives = 112/346 (32%), Gaps = 32/346 (9%) Query: 117 LEKQTQAVTEATTKQEANTTAINQAVSENKAIDQANRDEKARVDALNTKGEADTKAKNET 176 L+ T +V A T A VS Q + EK + + + + K + Sbjct: 15 LKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTLEKVQ-ERADKFEIENNTLKLKN 73 Query: 177 GQAQVDAQNKQAQ-AAADAMNAKLKADYEAKLTEIKQIESENEAIRQRNQQASQATHQAN 235 + + + + K + + S+ + + R +A Sbjct: 74 SDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKA----L 129 Query: 236 QAAQAAYQEKLAEIERIKAENAAIRDRNAKAQQEAERQNQALQAAYEAKLAEIKQIESEN 295 + A A+I+ ++AE AA+ R A ++ E Sbjct: 130 EGAMNFSTADSAKIKTLEAEKAALAARKADLEKALE--------GAMNFSTADSAKIKTL 181 Query: 296 AAIRQRNEQAGQATNQTNQAAQAAYQEKLAEIERIKAGNAAIRDRNAKAQQ---EAERQN 352 A + E + + A A+I+ ++A AA+ R A ++ A + Sbjct: 182 EAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFS 241 Query: 353 QALQAAYEAKLAEIKQIESENAAIRKRNEQAGQTTNQTNQAAQAAYQEKLAEIERINAEN 412 A A + AE +E+ A + K E A + A A + AE + AE Sbjct: 242 TADSAKIKTLEAEKAALEARQAELEKALEGA----MNFSTADSAKIKTLEAEKAALEAEK 297 Query: 413 AAIRDRNTKARQEAERQNQQLKTTYEAQLSAYQQALQAKKEAENKA 458 A E Q+Q L ++ + +AKK+ E + Sbjct: 298 AD-----------LEHQSQVLNANRQSLRRDLDASREAKKQLEAEH 332 Score = 31.6 bits (71), Expect = 0.022 Identities = 46/249 (18%), Positives = 88/249 (35%), Gaps = 29/249 (11%) Query: 100 KQSEKVTHDSLSSAQADLEKQTQAVTEATTKQEANTTAINQAVSENKAIDQANRDEKARV 159 ++ + + + A + ++A A + + ANR R Sbjct: 258 LEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRD 317 Query: 160 DALNTKGEADTKAKNETGQAQVDAQNK-------------QAQAAADAMNAKLKADYEAK 206 + + + +A+++ + Q +A+ +A + KL+ + Sbjct: 318 LDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKIS 377 Query: 207 LTEIKQIESENEAIRQRNQQASQATHQANQAAQA------AYQEKLAEIERIKAENAAIR 260 + + + +A R+ +Q +A +AN A +E E+ KAE A Sbjct: 378 EASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKL 437 Query: 261 DRNAKAQQEAERQNQALQAAYEAKLAEIKQIESENAAIRQRNE------QAGQATNQTNQ 314 + AKA +E A QA AKL K +S+ + N+ QA QA + NQ Sbjct: 438 EAEAKALKEKL----AKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQ 493 Query: 315 AAQAAYQEK 323 + K Sbjct: 494 NKAPMKETK 502
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 45.1 bits (106), Expect = 1e-06 Identities = 42/236 (17%), Positives = 84/236 (35%), Gaps = 17/236 (7%) Query: 383 RANIGWYPIANLWNEQSRDAIDTA--------EVGVPFFKITTQKMAQLEMAKAVANEGL 434 R G Y + N E+ +DT + VP +++A+++ A Sbjct: 972 RNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPA 1031 Query: 435 DEAKQAVKQAEANVTALEQVISQTSQAKEQLAAAKANLVTAKDMLDKAKQTAKLTEQDLE 494 ++ AE + + V A E A + AK + QT ++ + E Sbjct: 1032 TPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSE 1091 Query: 495 TKTANLKQAQEHLTLKQDDLAKAQTELAAQEKSLEQLTQVLSLAQENLGRATKAVEQTKA 554 TK + +E T+++++ AK +TE + + +Q + + Q +A Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVT--------SQVSPKQEQSETVQPQA 1143 Query: 555 DLTQKQAYVTNLKQVTKLRQESQAKVNQAKAVLSEASARLEQELETLKTLQAKEAN 610 + ++ N+K+ + A Q S + E T+ T + N Sbjct: 1144 EPARENDPTVNIKEPQSQ-TNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVEN 1198 Score = 43.5 bits (102), Expect = 3e-06 Identities = 42/248 (16%), Positives = 82/248 (33%), Gaps = 12/248 (4%) Query: 13 AALSTGTGLVQADDLSNTRPAKAAEVVTHTEVTENQVADAKTKADEATKAVKDQEATVKA 72 + S + + D+ PA A T V EN ++KT A A Sbjct: 1009 SVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDA-----TETTA 1063 Query: 73 IEAEKSQAQQSLVEATTAVNDTEKLASEA-------TPDGLTKAQEETEASQSAVTDAQA 125 E ++ +S V+A T N+ + SE T + T +EE ++ T Sbjct: 1064 QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVP 1123 Query: 126 QLEAAQEAESKAQTAVDHQKETVAKASQAVNQAKAALTTSNQAADVSAAEEKVLEAQEAV 185 ++ + + + V Q E + VN + T+ A A+E ++ V Sbjct: 1124 KVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPV 1183 Query: 186 TKAETQVSQAQEADAKHESDVRHAKEELDLKSQKLTEKQTTLEQVMAAIEAERLTKPVEN 245 T++ T + + + + ++ +S + + E T + Sbjct: 1184 TESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSND 1243 Query: 246 GTYFNQRD 253 + D Sbjct: 1244 RSTVALCD 1251 Score = 31.6 bits (71), Expect = 0.013 Identities = 29/133 (21%), Positives = 45/133 (33%), Gaps = 6/133 (4%) Query: 112 ETEASQSAVTDAQAQLEAAQEAESKAQTAVDHQKETVAKASQAVNQAKAALT---TSNQA 168 E E V +A+ +V E +A+ +A A T T+ Sbjct: 984 EVEKRNQTVDTTNITTPNNIQAD---VPSVPSNNEEIARVDEAPVPPPAPATPSETTETV 1040 Query: 169 ADVSAAEEKVLEAQEAVTKAETQVSQAQEADAKHESDVRHAKEELDLKSQKLTEKQTTLE 228 A+ S E K +E E T ++ +AK E+ + E QTT Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTET 1100 Query: 229 QVMAAIEAERLTK 241 + A +E E K Sbjct: 1101 KETATVEKEEKAK 1113 Score = 30.0 bits (67), Expect = 0.041 Identities = 27/148 (18%), Positives = 45/148 (30%), Gaps = 13/148 (8%) Query: 29 NTRPAKAAEVVTHTEVTENQVADAKTKADEATKAVKDQEAT---VKAIEAEKSQAQQSLV 85 + + + T T N V + AT + K ++ V Sbjct: 1175 TSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNV 1234 Query: 86 E-ATTAVNDTEKLAS---------EATPDGLTKAQEETEASQSAVTDAQAQLEAAQEAES 135 E ATT+ ND +A D KAQ AV+ +QLE E + Sbjct: 1235 EPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQY 1294 Query: 136 KAQTAVDHQKETVAKASQAVNQAKAALT 163 + + + + +K+ T Sbjct: 1295 NVWVSNTSMNKNYSSSQYRRFSSKSTQT 1322
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 29.4 bits (66), Expect = 0.003 Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 14/61 (22%) Query: 3 KKLVGFIVLALSTIILVACSNDSLEGE----------YYWINDARNQHMATIKGDKGYVE 52 KKL +VL LS IILVAC++ + I D I GDK + Sbjct: 2 KKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKN----IAGDKIDLH 57 Query: 53 S 53 S Sbjct: 58 S 58
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 61.2 bits (148), Expect = 1e-11 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 11/69 (15%) Query: 887 DPRTDADKNDPAGKNQQVKGKGN-----------KLPATGENATPFFNVAALTIISSVGL 935 D + G+ Q K N +LP+TGE A PFF AALT++++ G+ Sbjct: 470 DAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGV 529 Query: 936 LSVSKKKED 944 +V K+KE+ Sbjct: 530 AAVVKRKEE 538 Score = 46.2 bits (109), Expect = 5e-07 Identities = 14/55 (25%), Positives = 21/55 (38%) Query: 14 QTKQRFSIKKFKFGAASVLIGLSFLGGVTQGNLNIFEESIVAASTIPGSAATLNT 68 T + +S++K K G ASV + L+ LG N N + T Sbjct: 5 NTNRHYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTLEKVQERA 59
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.5 bits (209), Expect = 2e-19 Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 6/133 (4%) Query: 4 KVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALTYLTQYPVDVMISDVTMPGMT 63 +L+ DD+ I L + G++V + ++ D++++DV MP Sbjct: 5 TILVADDDAAIRTVLNQAL--SRAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 64 GLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQAKMKQFKDC 123 DL+ K P L L++S F KA E YL KP D L + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFD---LTELIGIIGRA 118 Query: 124 LDAQQAESIRQEA 136 L + + E Sbjct: 119 LAEPKRRPSKLED 131
>PF06580#Sensor histidine kinase Length = 349 Score = 25.6 bits (56), Expect = 0.019 Identities = 13/69 (18%), Positives = 24/69 (34%), Gaps = 14/69 (20%) Query: 1 MIQVLDNGRGISQERLADMEKRLQEHQTTGNSSIGLQNVYLRLFHHFRDRVSWSMAKEPN 60 ++V + G L T ++ GLQNV RL + ++++ Sbjct: 293 TLEVENTGS-------------LALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQ- 338 Query: 61 GGFIIQIRI 69 G + I Sbjct: 339 GKVNAMVLI 347
>PF06580#Sensor histidine kinase Length = 349 Score = 151 bits (383), Expect = 1e-43 Identities = 57/236 (24%), Positives = 104/236 (44%), Gaps = 20/236 (8%) Query: 251 LSKAYRMQYNRSGDLLAYVAVRKSYLLAEAVRTVFVYGLVSLLLAWLLLQLL-FRVFRNY 309 L+ AYR R G L + + A + + V+ W LL + + Sbjct: 55 LTHAYRSFIKRQG-WLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFT 113 Query: 310 IQQVSEITDTVEMVAAGDLSLTIDNSHMELELYHISEAINQMLASIKAYIDEVYVLEVEQ 369 + I V +V + M LY + +A ID+ + Sbjct: 114 LPLALSIIFNVVVV-----------TFMWSLLYF---GWHFFKNYKQAEIDQWK-MASMA 158 Query: 370 RDAQMRALQSQINPHFLYNTLEYIRMYALSCQQEELADVIYAFASLLRNNI--SQDKMTT 427 ++AQ+ AL++QINPHF++N L IR L + +++ + + L+R ++ S + + Sbjct: 159 QEAQLMALKAQINPHFMFNALNNIRALILE-DPTKAREMLTSLSELMRYSLRYSNARQVS 217 Query: 428 LKEELAFCEKYIYLYQMRYPDSFAYHVKIDESIADLAIPKFVIQPLVENYFVHGID 483 L +EL + Y+ L +++ D + +I+ +I D+ +P ++Q LVEN HGI Sbjct: 218 LADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA 273
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 61.9 bits (150), Expect = 1e-14 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 62 CLLARLDEKVVGLLNLSGEVLSQGQAEADVFMLVAKTYRGYGIGQLLLEIALDWAEENPY 121 L L+ +G + + E + VAK YR G+G LL A++WA+EN + Sbjct: 67 AFLYYLENNCIGRIKIRSNWNGYALIED---IAVAKDYRKKGVGTALLHKAIEWAKENHF 123 Query: 122 IESLKLDVQVRNTKAIYLYKKYGFRI 147 L L+ Q N A + Y K+ F I Sbjct: 124 C-GLMLETQDINISACHFYAKHHFII 148
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 32.0 bits (73), Expect = 0.005 Identities = 19/123 (15%), Positives = 43/123 (34%), Gaps = 8/123 (6%) Query: 372 LTAVSTAVCFLLSILLLPLVGIVPAAATAPALIVVGVMMVSSFLDVNWSKF--ADALPAF 429 L+ V V L PL+ + A A ++ G ++ + + K + Sbjct: 72 LSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKINPIEGAKRI 131 Query: 430 FAA-FFMALCYSISYGIAAAFIFYCLVK-----VVEGKTKDIHPIIWGATFLFIVNFIIL 483 F+ + SI + + + + ++K +++ T I I + +I Sbjct: 132 FSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVIC 191 Query: 484 TIL 486 T+ Sbjct: 192 TVG 194
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 27.1 bits (59), Expect = 0.014 Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 7/85 (8%) Query: 9 KQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTA-----TFTGDKKLVGIDFKEAVVDPED 63 +QAQK QK +K+ + A + ++L A + +K L + ++ + + Sbjct: 156 EQAQKAQKDKREKRKEERAKNRA--NLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQ 213 Query: 64 VETLQDMTTQAINDALTQIDEATKK 88 +E L+DM QA +AL QI+E KK Sbjct: 214 MERLEDMQEQAQANALKQIEELNKK 238
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 28.3 bits (63), Expect = 0.030 Identities = 14/57 (24%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Query: 133 KNQKAWKKLQWKMGISIFLAIVSY-VGLILLSSYLQKFWLVYVAMGLFLPGFSWLVI 188 + Q+ ++Q M L +V+ V ILLS + K ++ M LP + +++ Sbjct: 161 QRQQMRSRIQQAMIYPCVLTVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLM 217
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.3 bits (73), Expect = 0.001 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 10/102 (9%) Query: 84 EETKQRELLEILVDEKNTEITRLYEQLKAKDAQLASKDEQMRVKDVQIAEKDKQLDQQQQ 143 E ++E + +E++ T + AK+A+ K + Q E + + Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKA------NTQTNEVAQS--GSET 1092 Query: 144 LTAKAMADKETLKLELEE-AKAEADQARLQVEEVQAEVGPKK 184 + KET +E EE AK E ++ + +V +V ++V PK+ Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQ-EVPKVTSQVSPKQ 1133
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.0 bits (109), Expect = 3e-08 Identities = 21/118 (17%), Positives = 51/118 (43%), Gaps = 6/118 (5%) Query: 2 KILLIDDHRLFAKSIQLLFQQYD-EVDVIDTITSHFNDVTIDLSKYDIILLDINLTNISK 60 IL+ DD + + +V + + + + D+++ D+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI--AAGDGDLVVTDVVM---PD 59 Query: 61 ENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGFVDKNIDPKQLISILKK 118 EN ++ + ++ P L V++++ + +A + GAY ++ K D +LI I+ + Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 29.8 bits (67), Expect = 0.006 Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 11/85 (12%) Query: 1 MKKKERHEKILDILKVDGFIKVKDIIDEM-----NISDMTARRDLDTLADKGLL-IRTHG 54 M K +RH KI +I+ + +++D + N++ T RD+ L L+ + T+ Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKEL---HLVKVPTNN 57 Query: 55 GAQYLDYSSAKDEGHEKTHTEKKVL 79 G+ YS D+ K+ L Sbjct: 58 GSYK--YSLPADQRFNPLSKLKRSL 80
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 29.8 bits (67), Expect = 0.008 Identities = 8/44 (18%), Positives = 17/44 (38%), Gaps = 2/44 (4%) Query: 227 INGYKVTSWNDLTEAV-DLATRD-LGPSQTIKVTYKSHQRLKTV 268 + ++ L E + DL +D + +Q+LK + Sbjct: 80 FDITEIGEQYSLKETIQDLCAKDFHQKLKEFTEKTPKNQKLKDL 123
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 64.7 bits (157), Expect = 1e-13 Identities = 37/87 (42%), Positives = 44/87 (50%), Gaps = 1/87 (1%) Query: 224 ETPEQPGEKAPEKSKEVTPAPEKPADKEANQTPE-RRNGNMAKTPVANNHRRLPATGEQA 282 E + S+ P A Q P+ N K P+ R+LP+TGE A Sbjct: 453 EELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETA 512 Query: 283 NPFFTAAAVAVMTTAGVLAVTKRKENN 309 NPFFTAAA+ VM TAGV AV KRKE N Sbjct: 513 NPFFTAAALTVMATAGVAAVVKRKEEN 539
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.7 bits (79), Expect = 6e-04 Identities = 14/56 (25%), Positives = 20/56 (35%), Gaps = 9/56 (16%) Query: 34 IVFVGPSGCGKSTTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALY 89 +V G G GKST + + GL+ S+ IG +D Y Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG---------TGKDSYEQIAGIVAY 645
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 7e-04 Identities = 10/30 (33%), Positives = 19/30 (63%) Query: 243 ALWSEHGNLVQTAQRLYIHRNSLQYKLDKF 272 AL + GN ++ A L ++RN+L+ K+ + Sbjct: 444 ALTATRGNQIKAADLLGLNRNTLRKKIREL 473
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 767 bits (1982), Expect = 0.0 Identities = 374/440 (85%), Positives = 391/440 (88%), Gaps = 8/440 (1%) Query: 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLDRPSVNNSQLVVSVAGTVEGTNQEIS 60 MKNYLSFGMFALLFALTFGTV VQAIAGPEWLLDRPSVNNSQLVVSVAGTVEGTNQ+IS Sbjct: 1 MKNYLSFGMFALLFALTFGTVNSVQAIAGPEWLLDRPSVNNSQLVVSVAGTVEGTNQDIS 60 Query: 61 LKFFEIDLTSRPAQGGKTEPGLRPKSK--------MPYKLEKADLLKAIQEQLIANVHSN 112 LKFFEIDLTSRPA GGKTE GL PKSK M +KLEKADLLKAIQEQLIANVHSN Sbjct: 61 LKFFEIDLTSRPAHGGKTEQGLSPKSKPFATDSGAMSHKLEKADLLKAIQEQLIANVHSN 120 Query: 113 DGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNS 172 D YFEVIDFASDATITDRNGKVYFAD+D SVTLPTQPVQEFLLSGHVRVRPY+ K + N Sbjct: 121 DDYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLSGHVRVRPYKEKPIQNQ 180 Query: 173 AERVNVNYEVSFVSETGDLDFTPSLRDRYHLTTLAVGDSLSSQELAAIAQFILSKEHPDY 232 A+ V+V Y V F D DF P L+D L TLA+GD+++SQEL A AQ IL+K HP Y Sbjct: 181 AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKNHPGY 240 Query: 233 IITKRDSSIVTHDNDIFRTILPMDQEFTYHVKDREQAYGINKKSGQKEKINNTDLISEKY 292 I +RDSSIVTHDNDIFRTILPMDQEFTY VK+REQAY INKKSG E+INNTDLISEKY Sbjct: 241 TIYERDSSIVTHDNDIFRTILPMDQEFTYRVKNREQAYRINKKSGLNEEINNTDLISEKY 300 Query: 293 YVLKKGEKPYDPFDRSHLKLFTINYVDVDTNKLLKSEQLLTASERNLDFRDLYDPRDKAK 352 YVLKKGEKPYDPFDRSHLKLFTI YVDVDTN+LLKSEQLLTASERNLDFRDLYDPRDKAK Sbjct: 301 YVLKKGEKPYDPFDRSHLKLFTIKYVDVDTNELLKSEQLLTASERNLDFRDLYDPRDKAK 360 Query: 353 LLYNNLDAFGIMDYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEER 412 LLYNNLDAFGIMDYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEER Sbjct: 361 LLYNNLDAFGIMDYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEER 420 Query: 413 EVYSYLRYTGTPIPDNPKDK 432 EVYSYLRYTGTPIPDNP DK Sbjct: 421 EVYSYLRYTGTPIPDNPNDK 440
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 63.5 bits (154), Expect = 4e-13 Identities = 43/130 (33%), Positives = 56/130 (43%), Gaps = 3/130 (2%) Query: 254 EAGKPGEKAPEKSPEVTPTPETPEQP---GEKAPEKSPEVTPTPEMPEQPGEKAPEKSKE 310 A + K E+S ++T + Q E K E+ + KA + Sbjct: 410 AALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTP 469 Query: 311 VTPAPEKPADKEANQTPERRNGNMAKTPVANNHRRLPATGEQANPFFTAAAVAVMTTAGV 370 K + N K P+ R+LP+TGE ANPFFTAAA+ VM TAGV Sbjct: 470 DAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGV 529 Query: 371 LAVTKRKENN 380 AV KRKE N Sbjct: 530 AAVVKRKEEN 539
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 34.0 bits (77), Expect = 0.003 Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 2/87 (2%) Query: 226 IPKKDLSPSELAAAQAYWSQKQGRGARPSDY-RPTPAPGRRKAPIPDVTPNPGRGHQPD- 283 IP+ DL+P A A + P++ P PG R P PD NP D Sbjct: 310 IPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDG 369 Query: 284 NGGYHPAPPRPNDASQNKHQRDEFKGK 310 G P P D +H+++ +G+ Sbjct: 370 QPGTRPDSPAVPDRPNGRHRKERKEGE 396
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 247 bits (631), Expect = 5e-83 Identities = 82/323 (25%), Positives = 143/323 (44%), Gaps = 34/323 (10%) Query: 1 MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVR-MI 59 MKK L+ + +S +++ C Q + VV + + +TK ++GD D+ ++ Sbjct: 1 MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIV 60 Query: 60 QSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLE----AWARDLDPNLKKSKVDVFEASKP 115 G H +EP DV +ADL Y+ LE AW L N KK++ + A Sbjct: 61 PIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFA--- 117 Query: 116 LTLDRVKGLEDMEVTQGIDPATLY--------DPHTWTDPVLAGEEAVNIAKELGRLDPK 167 V+ G+D L DPH W + A NIAK+L DP Sbjct: 118 -------------VSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPN 164 Query: 168 HKDSYTKKAKAFKKEAEQLTEEYTQKFKKVR--SKTFVTQHTAFSYLAKRFGLKQLGISG 225 +K+ Y K K + + ++L +E KF K+ K VT AF Y +K +G+ I Sbjct: 165 NKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWE 224 Query: 226 ISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT---LSPLEA 282 I+ E+E +P Q+K + + +++ V ++F E +V+ + +++ T + + Sbjct: 225 INTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAE 284 Query: 283 APSGNKTYLENLRANLEVLYQQL 305 +Y ++ NL+ + + L Sbjct: 285 QGKEGDSYYSMMKYNLDKIAEGL 307
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 53.1 bits (127), Expect = 1e-09 Identities = 52/331 (15%), Positives = 99/331 (29%), Gaps = 30/331 (9%) Query: 2 QSISSTQGNTANTSQKWYDINEHGIIPVDISLETAKEDFKKEVEKSRLSKEQQKTYNQKI 61 Q++ +T T N Q +P S + +T Sbjct: 990 QTVDTTNITTPNNIQA--------DVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA 1041 Query: 62 EAAKNKDDLLLTYHREYSEDIKKHSASTEPTTQPVEAPVQETQASASDSMVTDDSTSVTT 121 E +K + + ++ +E ++ + V+A Q + + S S + T+ T Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 122 DSPKESP----------VAPASSPESEKSSVAASSEETSSPETPAAPEAPALSEAPVQPA 171 ++ S+ S SE PA P ++ Q Sbjct: 1102 ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQ 1161 Query: 172 ESEEPSVAAPSEETPSPAAPE-----TPEEPAAPAPSPESEEPSVAASSEETPSPAAPAL 226 + P++ET S T + +PE+ P+ + + S P Sbjct: 1162 TNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKN 1221 Query: 227 SEAPAQPAESEKPSVAASSEETPSPSTPAESETQTPPAVTKDSDKPSSAAEKPAASSLVS 286 + + A +S S + + AV S A K +L Sbjct: 1222 RHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVL------SDARAKAQFVALNV 1275 Query: 287 EQTVQQPTSKRSSDKKEEQEQSYSPNRSLSR 317 + V Q S+ + E Q + N S+++ Sbjct: 1276 GKAVSQHISQLEMN-NEGQYNVWVSNTSMNK 1305 Score = 52.0 bits (124), Expect = 2e-09 Identities = 41/248 (16%), Positives = 73/248 (29%), Gaps = 24/248 (9%) Query: 85 HSASTEPTTQPVEAPVQETQASASDSMVTDDSTSVTTDSPKESPVAPASSP--------- 135 ++ E Q V+ T + + + S + E+PV P + Sbjct: 981 YNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETV 1040 Query: 136 -ESEKSSVAASSEETSSPETPAAPEAPALSEA----PVQPAESEEPSVAAPSEETPSPAA 190 E+ K + A EA +E + ++ET + Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTET 1100 Query: 191 PETP----EEPAAPAPSPESEEPSVAASSEETPSPAAPALSEAPAQPAESEKPSVAASSE 246 ET EE A E P V S+ +P + A+PA P+V Sbjct: 1101 KETATVEKEEKAKVETEKTQEVPKVT--SQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 247 ETPSPSTPAESE--TQTPPAVTK--DSDKPSSAAEKPAASSLVSEQTVQQPTSKRSSDKK 302 ++ + +T + +T V + + + + QPT S K Sbjct: 1159 QSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNK 1218 Query: 303 EEQEQSYS 310 + S Sbjct: 1219 PKNRHRRS 1226 Score = 42.7 bits (100), Expect = 2e-06 Identities = 37/204 (18%), Positives = 68/204 (33%), Gaps = 17/204 (8%) Query: 125 KESPVAPASSPESEKSSVAASSEETSSPETPAAPEAPALSEAPVQPAESEE------PSV 178 + V + S +++ E EAP AP P+E+ E Sbjct: 988 RNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQE 1047 Query: 179 AAPSEETPSPAAPETPE-----EPAAPAPSPESEEPSVAASSEETPSPAAPALSEAPAQP 233 + E+ A T + + A ++ VA S ET E Sbjct: 1048 SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE 1107 Query: 234 AESEKPSVAASSEETPS-----PSTPAESETQTPPAVTKDSDKPSSAAEKPAASSLVSEQ 288 E + ++E P +SET P A + P+ ++P + + + Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQT-NTTA 1166 Query: 289 TVQQPTSKRSSDKKEEQEQSYSPN 312 +QP + SS+ ++ +S + N Sbjct: 1167 DTEQPAKETSSNVEQPVTESTTVN 1190
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 106 bits (266), Expect = 6e-27 Identities = 49/226 (21%), Positives = 84/226 (37%), Gaps = 47/226 (20%) Query: 117 KAGKGAGTVVAVIDAGFDKNHEAWRLTDKAKARYQSKEDLEKAKKEHGITYGEWVNDKVA 176 +G G VAV+D G D +H DL KA+ G + + Sbjct: 36 NQTRGRGVKVAVLDTGCDADH----------------PDL-KARIIGGRNFTDDDEGDPE 78 Query: 177 YYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLA 236 + DY+ HGTHV+G ++ + G PEA LL+++V G Sbjct: 79 IFKDYNG---------HGTHVAGTIAATENE-----NGVVGVAPEADLLIIKVLNKQGSG 124 Query: 237 DYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGND 296 Y Q I A+ +I+MS G E +A A + + ++ +AGN+ Sbjct: 125 QYD-WIIQGIYYAIEQKVDIISMSLGGPE-----DVPELHEAVKKAVASQILVMCAAGNE 178 Query: 297 SSFGGKPRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETAT 342 + +G P + ++V + + D+ +E + Sbjct: 179 GDGDDR----------TDELGYPGCYNEVISVGAINFDRHASEFSN 214 Score = 79.9 bits (197), Expect = 5e-18 Identities = 37/139 (26%), Positives = 58/139 (41%), Gaps = 22/139 (15%) Query: 457 NATPKVLPTASGTK---LSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSM 513 +V+ + S FS+ + D+ APG+DILS+V KYA SGTSM Sbjct: 192 GCYNEVISVGAINFDRHASEFSNSNN------EVDLVAPGEDILSTVPGGKYATFSGTSM 245 Query: 514 SAPLVAGIMGL-LQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGA 572 + P VAG + L Q + D+T E L+ L + SP+ +G Sbjct: 246 ATPHVAGALALIKQLANASFERDLTEPE----LYAQLIKRTIPLGN-------SPKMEGN 294 Query: 573 GAVDAKKASA-ATMYVTDK 590 G + + ++ T + Sbjct: 295 GLLYLTAVEELSRIFDTQR 313
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 116 bits (291), Expect = 9e-31 Identities = 157/384 (40%), Positives = 210/384 (54%), Gaps = 38/384 (9%) Query: 5 QTKKNYSLRKLKTGTASVAVALTVLGAGFANQTEVRADEAKKMEVKESEKESQYKTLALR 64 K + A A L T A K + + Sbjct: 175 SAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKAL 234 Query: 65 GENADLRNVNAKYLEKINAE----EEKNKKLEAINKELNENYYKLQDGIDALEKEKEDLK 120 + ++ ++ + AE E + +LE + I LE EK L+ Sbjct: 235 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALE 294 Query: 121 TTLAKTTKENEISEASRKGLSRDLEASRTAKKELEAKHQKLEAENKKLTEGNQVSEASRK 180 A ++++ A+R+ L RDL+ASR AKK+LEA+HQKLE E N++SEASR+ Sbjct: 295 AEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLE-------EQNKISEASRQ 347 Query: 181 GLSNDLEASRAAKKELEAKYQKLETDHQALEAKHQKLEADYQVSETSRKGLSRDLEASRE 240 L DL+ASR AKK+LEA+ HQKLE ++SE SR+ L RDL+ASRE Sbjct: 348 SLRRDLDASREAKKQLEAE--------------HQKLEEQNKISEASRQSLRRDLDASRE 393 Query: 241 ANKKVTSELTQAKAQLSALE-------ESKKLSEKEKAELQAKLDAQGKALKEQLAKQTE 293 A K+V L +A ++L+ALE ESKKL+EKEKAELQAKL+A+ KALKE+LAKQ E Sbjct: 394 AKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAE 453 Query: 294 ELAKLRAEKAAGSKTPATKPANNERSGR--AAQTATRPSQNKG----MRSQLPSTGEAAN 347 ELAKLRA KA+ S+TP KP N G+ A Q T+P+QNK + QLPSTGE AN Sbjct: 454 ELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETAN 513 Query: 348 PFFTAAAATVMVSAGMLALKRKEE 371 PFFTAAA TVM +AG+ A+ +++E Sbjct: 514 PFFTAAALTVMATAGVAAVVKRKE 537 Score = 82.4 bits (203), Expect = 2e-19 Identities = 84/303 (27%), Positives = 127/303 (41%), Gaps = 15/303 (4%) Query: 1 MARQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTEVRADEAKKMEVKESEKESQYKT 60 M + T ++YSLRKLKTGTASVAVALTVLGAG T + A + + EK Sbjct: 1 MTKNNTNRHYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTLEK------ 54 Query: 61 LALRGENADLRNVNAKYLEKINAEEEKNKKLEAINKELNENYYKLQDGIDALEKEKEDLK 120 ++ K+ + N + KN L NK L ++ +L + + +++ Sbjct: 55 ---------VQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKND 105 Query: 121 TTLAKTTKENEISEASRKGLSRDLEASRTAKKELEAKHQKLEAENKKLTEGNQVSEASRK 180 +L++ + + EA + L + LE + AK + LEAE L E + + Sbjct: 106 KSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALE 165 Query: 181 GLSNDLEASRAAKKELEAKYQKLETDHQALEAKHQKLEADYQVSETSRKGLSRDLEASRE 240 G N A A K LEA+ LE LE + K L + A Sbjct: 166 GAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAA 225 Query: 241 ANKKVTSELTQAKAQLSALEESKKLSEKEKAELQAKLDAQGKALKEQLAKQTEELAKLRA 300 + L A +A K E EKA L+A+ KAL+ + T + AK++ Sbjct: 226 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKT 285 Query: 301 EKA 303 +A Sbjct: 286 LEA 288
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 84.0 bits (207), Expect = 5e-20 Identities = 150/306 (49%), Positives = 196/306 (64%), Gaps = 21/306 (6%) Query: 50 KKEAKLSEAELHDKIKNLEEEKAELFEKLDKVEEEHKKVEEEHKKDHEKLEKKSEDVERH 109 + A KIK LE EKA L + ++E+ + D K++ + Sbjct: 234 LEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA- 292 Query: 110 YLRQLDQEYKEQQERQKNLEELERQSQREVEKRYQEQLQKQQQLEKEKQISEASRKSLSR 169 L + + Q + + R+ + ++ + Q+LE++ +ISEASR+SL R Sbjct: 293 -LEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRR 351 Query: 170 DLEASRAAKKDLEAEHQKLKEEKQISEASRQGLSRDLEASREAKKKVEADLAEANSKLQA 229 DL+ASR AKK LEAEHQKL+E+ +ISEASRQ L RDL+ASREAKK+VE L EANSKL A Sbjct: 352 DLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAA 411 Query: 230 LEKLNKELEEGKKLSEKEKAELQAKLEAEAKALKEQLAKQAEELAKLK-----GNQTPNA 284 LEKLNKELEE KKL+EKEKAELQAKLEAEAKALKE+LAKQAEELAKL+ +QTP+A Sbjct: 412 LEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDA 471 Query: 285 KVAPQA--------------NRSRSAMTQQKRTLPSTGETANPFFTAAAATVMVSAGMLA 330 K +A N++++ M + KR LPSTGETANPFFTAAA TVM +AG+ A Sbjct: 472 KPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAA 531 Query: 331 LKRKEE 336 + +++E Sbjct: 532 VVKRKE 537 Score = 50.4 bits (120), Expect = 4e-09 Identities = 68/304 (22%), Positives = 118/304 (38%), Gaps = 7/304 (2%) Query: 1 MARKDTNKQYSLRKLKTGTASVAVAVAVLGAGFANQTTVKANSKNPVPVKKEAKLSEAEL 60 M + +TN+ YSLRKLKTGTASVAVA+ VLGAG T + K+ E Sbjct: 1 MTKNNTNRHYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTLEKVQER-- 58 Query: 61 HDKIKNLEEEKAELFEKLDKVEEEHKKVEEEHKKDHEKLEKKSEDVERHYLRQLDQEYKE 120 E E L K + +K +++ + + E+L E + ++ ++ K Sbjct: 59 ---ADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKI 115 Query: 121 QQERQKNLEELERQSQREVEKRYQEQLQKQQQLEKEKQISEASRKSLSRDLEASRAAKKD 180 Q+ + + ++ K + LE EK A + L + LE + Sbjct: 116 QELEARKAD--LEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTA 173 Query: 181 LEAEHQKLKEEKQISEASRQGLSRDLEASREAKKKVEADLAEANSKLQALEKLNKELEEG 240 A+ + L+ EK EA + L + LE + A + ++ AL +LE+ Sbjct: 174 DSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKA 233 Query: 241 KKLSEKEKAELQAKLEAEAKALKEQLAKQAEELAKLKGNQTPNAKVAPQANRSRSAMTQQ 300 + + AK++ A+QAE L+G + + + + Sbjct: 234 LEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAAL 293 Query: 301 KRTL 304 + Sbjct: 294 EAEK 297 Score = 42.0 bits (98), Expect = 2e-06 Identities = 52/206 (25%), Positives = 90/206 (43%), Gaps = 2/206 (0%) Query: 50 KKEAKLSEAELHDKIKNLEEEKAELFEKLDKVEEEHKKVEEEHKKDHEKLEKKSEDVERH 109 + A KIK LE EKA L + ++E+ + D K++ + Sbjct: 164 LEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKA-- 221 Query: 110 YLRQLDQEYKEQQERQKNLEELERQSQREVEKRYQEQLQKQQQLEKEKQISEASRKSLSR 169 L + ++ E N + + +E +Q +LEK + + + S Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 170 DLEASRAAKKDLEAEHQKLKEEKQISEASRQGLSRDLEASREAKKKVEADLAEANSKLQA 229 ++ A K LEAE L+ + Q+ A+RQ L RDL+ASREAKK++EA+ + + + Sbjct: 282 KIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKI 341 Query: 230 LEKLNKELEEGKKLSEKEKAELQAKL 255 E + L S + K +L+A+ Sbjct: 342 SEASRQSLRRDLDASREAKKQLEAEH 367
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 137 bits (347), Expect = 7e-38 Identities = 127/353 (35%), Positives = 187/353 (52%), Gaps = 17/353 (4%) Query: 89 SKLMQQMYKETLQKKEELDTLSKALTHTIEKKIESENAYKKELGQLKAAAEAEAQKALDA 148 + Q ++ L+ T A T+E + + A K +L + A + Sbjct: 188 LEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAK 247 Query: 149 LNNKNKQISDLTNENAQLKEAIEGYVQ-------TIQNASREMAAKQQELAAAKSQLEAK 201 + + + L A+L++A+EG + I+ E AA + E A + Q + Sbjct: 248 IKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVL 307 Query: 202 NAEIEALKQQDASKTEELAKLQSEAATLENLLGSAKRELTELQAKLDTATAEKAKLESQV 261 NA ++L++ + E +L++E LE ++ L+ LD + K +LE++ Sbjct: 308 NANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEH 367 Query: 262 TTLENLLGSAKRELTDLQAKLDAANAEKEKLQSQAAALEKQLEATKKELADLQAKLAATN 321 LE ++ L+ LDA+ K++++ +L A +K +L+ T Sbjct: 368 QKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTE 427 Query: 322 QEKE----KLEAEAKALKEQLAKQAEELAKLKADKASGAQKPDTKPGNKEVPTR----PS 373 +EK KLEAEAKALKE+LAKQAEELAKL+A KAS +Q PD KPGNK VP + + Sbjct: 428 KEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQA 487 Query: 374 QTRTNTNKAPMAQTKRQLPSTGEETTNPFFTAAALTVIASAGVLA-LKRKEEN 425 T+ N NKAPM +TKRQLPSTG ET NPFFTAAALTV+A+AGV A +KRKEEN Sbjct: 488 GTKPNQNKAPMKETKRQLPSTG-ETANPFFTAAALTVMATAGVAAVVKRKEEN 539 Score = 84.0 bits (207), Expect = 1e-19 Identities = 94/352 (26%), Positives = 154/352 (43%), Gaps = 13/352 (3%) Query: 1 MSKRNPNKHYSLRKLKTGTASVAVALTVLGAGLANTTDVKAETVGRFSDEQVRKAREKAI 60 M+K N N+HYSLRKLKTGTASVAVALTVLGAGL T+ + R + + K +E+A Sbjct: 1 MTKNNTNRHYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTLEKVQERA- 59 Query: 61 EDVFDGYTGARSVYQSGNLPNRLTPTKLSKLMQQMYKETLQKKEELDTLSKALTHTIEKK 120 D + + + N L ++ +E KE+L K+L+ K Sbjct: 60 ----DKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEK-ASK 114 Query: 121 IESENAYKKELGQLKAAAEAEAQKALDALNNKNKQISDLTNENAQLKEAIEGYVQTIQNA 180 I+ A K +L + A + + + + L A L++A+EG + N Sbjct: 115 IQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAM----NF 170 Query: 181 SREMAAKQQELAAAKSQLEAKNAEIEALKQQDASKTEELAKLQSEAATLENLLGSAKREL 240 S +AK + L A K+ LEA+ AE+E + ++ TLE + Sbjct: 171 STADSAKIKTLEAEKAALEARQAELEKALEG---AMNFSTADSAKIKTLEAEKAALAARK 227 Query: 241 TELQAKLDTATAEKAKLESQVTTLENLLGSAKRELTDLQAKLDAANAEKEKLQSQAAALE 300 +L+ L+ A +++ TLE + + +L+ L+ A ++ LE Sbjct: 228 ADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLE 287 Query: 301 KQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLAKQAEELAKLKADK 352 + A + E ADL+ + N ++ L + A +E + E KL+ Sbjct: 288 AEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQN 339 Score = 30.4 bits (68), Expect = 0.016 Identities = 36/203 (17%), Positives = 75/203 (36%) Query: 160 TNENAQLKEAIEGYVQTIQNASREMAAKQQELAAAKSQLEAKNAEIEALKQQDASKTEEL 219 T+ +++E + + + + A K + E+ K++ + L Sbjct: 49 TDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSL 108 Query: 220 AKLQSEAATLENLLGSAKRELTELQAKLDTATAEKAKLESQVTTLENLLGSAKRELTDLQ 279 ++ S+ LE ++ L +A+ LE++ L ++ L Sbjct: 109 SEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAM 168 Query: 280 AKLDAANAEKEKLQSQAAALEKQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLA 339 A +A+ + L+++ AALE + +K L A + + + LEAE AL + A Sbjct: 169 NFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKA 228 Query: 340 KQAEELAKLKADKASGAQKPDTK 362 + L + + K T Sbjct: 229 DLEKALEGAMNFSTADSAKIKTL 251
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 43.9 bits (103), Expect = 2e-06 Identities = 49/262 (18%), Positives = 80/262 (30%), Gaps = 23/262 (8%) Query: 361 KPAEDERSSQATEPANPSKEDSSTDASQGSHDSENPATDSPSQPQAPDQGNHQSQVPNDK 420 + QA P+ PS + + PAT S + + +S+ Sbjct: 995 TNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN 1054 Query: 421 PQ-----------TDKTDTPNVPAPPQDTPKAPEAGGQSGPAGNTEEKAPDSGPKESDQ- 468 Q K NV A Q T + ++G ++ TE K + KE Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQ-TNEVAQSGSETKETQTTETKETATVEKEEKAK 1113 Query: 469 ---SSSKESPSVGEDTTPNQPDVLVGGQSEPIDITEDTITDAPPTVSGHNASTQPQSVAE 525 ++E P V +P Q QSE + + + PTV+ +Q + A+ Sbjct: 1114 VETEKTQEVPKVTSQVSPKQE------QSETVQPQAEPARENDPTVNIKEPQSQTNTTAD 1167 Query: 526 DTAPQRPDVLVGGQSEPIDITQDTQPGMSGSNDATVINEDTKPKRVFHFDNKEPQASEKA 585 P + Q T +T + N T+P NK ++ Sbjct: 1168 TEQPAKETSSNVEQPVTESTTVNTGNSVV-ENPENTTPATTQPTVNSESSNKPKNRHRRS 1226 Query: 586 AEQKLAPHDSHTTPQTSDDTAA 607 + TT T A Sbjct: 1227 VRSVPHNVEPATTSSNDRSTVA 1248 Score = 37.0 bits (85), Expect = 3e-04 Identities = 31/223 (13%), Positives = 64/223 (28%), Gaps = 14/223 (6%) Query: 237 ELLGLKAEIDQLTKDNPKNDRLETLMWESKFTLSDFRRTSRLSAYYTQEDYVDKVVLSEE 296 E + ++ + T + + D ET + TQ + V + + Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVK----ANTQTNEVAQSGSETK 1093 Query: 297 APNLRTAKEKVKTLKGILYDYYVETNDLEKAKQYRVEDETSPSQPEAPAKPEAPTPSPSP 356 KE K VET ++ + + Q E P P Sbjct: 1094 ETQTTETKETATVEKE--EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 357 APGQKPAEDERSSQATEPANPSKEDSSTDASQGSHDSENPATDSPSQPQAPDQGNHQSQV 416 K + + ++ A P+KE SS + + +S + N ++ Sbjct: 1152 TVNIKEPQSQTNTTADT-EQPAKETSSNVEQPVTESTTVNTGNSVVE-------NPENTT 1203 Query: 417 PNDKPQTDKTDTPNVPAPPQDTPKAPEAGGQSGPAGNTEEKAP 459 P T +++ N P ++ +++ Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRST 1246
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.6 bits (71), Expect = 0.019 Identities = 28/140 (20%), Positives = 47/140 (33%), Gaps = 14/140 (10%) Query: 24 APTVLGQEVSASTTSTETSAASAGVGTSGTAASETGSGAAVATATTTTATTNGGPQSTPA 83 PTV +E + T +T + A +S T S TT T N ++ Sbjct: 1150 DPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTES--------TTVNTGNSVVENPEN 1201 Query: 84 VAEATPQPQAQIAPVAAATSTSSASSSSDGKAPQAVTSSTSPSTPAA------ASSNGSN 137 AT QP + S S + T+S++ + A ++N Sbjct: 1202 TTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVL 1261 Query: 138 QEASAETEPQTMEVEKYTVD 157 +A A+ + + V K Sbjct: 1262 SDARAKAQFVALNVGKAVSQ 1281
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 24.9 bits (54), Expect = 0.043 Identities = 4/24 (16%), Positives = 7/24 (29%) Query: 22 YSKKVLTDEPTGYQPPAAHGPCDD 45 + + + T AA D Sbjct: 27 KNPQPQAQQTTQTTTTAAGSAADQ 50
>STREPTOPAIN#Streptopain (C10) cysteine protease family signature. Length = 398 Score = 59.7 bits (144), Expect = 4e-14 Identities = 39/102 (38%), Positives = 56/102 (54%), Gaps = 7/102 (6%) Query: 2 EMHFVRTEPEARRIAETFCAENTQTKTPMRVQQLSYPSDTDHSGGEL-----YIYALSPA 56 + +F R E EA+ A TF ++ K R + D + GGEL Y+Y +S Sbjct: 28 DQNFARNEKEAKDSAITFIQKSAAIKAGARSAE-DIKLDKVNLGGELSGSNMYVYNISTG 86 Query: 57 GFIIVSGDTRAHTILGYSFDNNLDLN-HDNVRSMIEAYQKQI 97 GF+IVSGD R+ ILGYS + D N +N+ S +E+Y +QI Sbjct: 87 GFVIVSGDKRSPEILGYSTSGSFDANGKENIASFMESYVEQI 128
>STREPTOPAIN#Streptopain (C10) cysteine protease family signature. Length = 398 Score = 710 bits (1833), Expect = 0.0 Identities = 396/398 (99%), Positives = 397/398 (99%) Query: 1 MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAITFIQKSAAIKAGARSAE 60 MNKKKLG+RLLSLLALGGFVLANPVFADQNFARNEKEAKDSAITFIQKSAAIKAGARSAE Sbjct: 1 MNKKKLGVRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAITFIQKSAAIKAGARSAE 60 Query: 61 DIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILGYSTSGSFDANGKENIASF 120 DIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILGYSTSGSFDANGKENIASF Sbjct: 61 DIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILGYSTSGSFDANGKENIASF 120 Query: 121 MESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGE 180 MESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGE Sbjct: 121 MESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGE 180 Query: 181 QSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQY 240 QSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQY Sbjct: 181 QSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQY 240 Query: 241 NWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQ 300 NWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQ Sbjct: 241 NWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQ 300 Query: 301 SVHQINRSDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWG 360 SVHQINR DFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWG Sbjct: 301 SVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWG 360 Query: 361 GVSDGFFRLDALNPSALGTGGGAGGFNGYQSAVVGIKP 398 GVSDGFFRLDALNPSALGTGGGAGGFNGYQSAVVGIKP Sbjct: 361 GVSDGFFRLDALNPSALGTGGGAGGFNGYQSAVVGIKP 398
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 47.4 bits (113), Expect = 7e-08 Identities = 22/53 (41%), Positives = 32/53 (60%), Gaps = 6/53 (11%) Query: 46 IAIKDGLIVALG-SGEPDAE-----LVGPQTIMRSYKGKIATPGIIDCHTHLV 92 I +KDG I A+G +G PD + +VGP T + + +GKI T G +D H H + Sbjct: 88 IGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFI 140
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.8 bits (69), Expect = 0.021 Identities = 20/118 (16%), Positives = 35/118 (29%), Gaps = 17/118 (14%) Query: 438 NAYYDPQQNQIVFPAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDT---------N 488 + + A + S+ N+ +G + + N Sbjct: 594 YLNLENYTYYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFN 653 Query: 489 GASFDEHGSLNDWWTQEDYAAFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGG 546 G +E G N FK ++++ G G +NG LTV + L G Sbjct: 654 GYFGEEEGKNNGNLN----VTFKGKSEQNRFLLTG----GTNLNGDLTVEKGTLFLSG 703
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.007 Identities = 6/18 (33%), Positives = 12/18 (66%) Query: 610 LVKQGDQVKAGQTLIQFD 627 +VK+G+ V+ G L++ Sbjct: 111 IVKEGESVRKGDVLLKLT 128
>FIMBRILLIN#Porphyromonas gingivalis: fimbrillin protein signature. Length = 348 Score = 24.2 bits (52), Expect = 0.040 Identities = 13/54 (24%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 6 LKAARINAGYTLKQVAGAVGKNPQTISKYEKDSSDISLGLLQKLSSLYGVTIDN 59 L+ R++A ++ V +P ++KY +I + +K S+L+G ++ N Sbjct: 127 LEIKRVHARMAFTEIK--VQMSPSYVNKYNFAPENIYALVAKKESNLFGASLAN 178
>PF05272#Virulence-associated E family protein Length = 892 Score = 333 bits (856), Expect = e-108 Identities = 86/359 (23%), Positives = 141/359 (39%), Gaps = 19/359 (5%) Query: 26 RGDKEYVISSPYNVGKVFEFYENIYTGIKYNEFEKTIEITKAVPWSKEKGLWTNEQTSLC 85 + + + + + + ++E + +A PW K G + Sbjct: 442 LRGRWLLKPRRAALIEALRSAPALAGCVAFDELREQPVAVRAFPWRKAPGPLEDADVLRL 501 Query: 86 IAFIDEKYRF-TPRKEHIEVAITALAKKNTYHPIKQRIESQKWDGKARGERYFIDLLGCA 144 +++ Y + E AI A N HP + +++Q+WD R E++ + +LG Sbjct: 502 ADYVETTYGTGEASAQTTEQAINVAADMNRVHPFRDWVKAQQWDEVPRLEKWLVHVLGKT 561 Query: 145 DNSYN-------REIAKVWLTGLMARIYLRKVKFEVVPILIDKRQGTGKSTVTKRLLP-S 196 + Y + + K L G +AR+ KF+ +L + G GKST+ L+ Sbjct: 562 PDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYSVVL-EGTGGIGKSTLINTLVGLD 620 Query: 197 YHTDSEIKFGKNDSDYQKIQANAIIELGELKGMSKAEIETVKSFISSDSDTYREPYERKA 256 + +D+ G Y++I EL E+ +A+ E VK+F SS D YR Y R Sbjct: 621 FFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRRADAEAVKAFFSSRKDRYRGAYGRYV 680 Query: 257 TPHPRHCVFIGTANKKSFLKDSGTERRFFPIECGINDVKKHPMEVEEDYFLQVLAEAKVW 316 HPR V T NK+ +L D RRF+P+ ++ Q+ AEA Sbjct: 681 QDHPRQVVIWCTTNKRQYLFDITGNRRFWPVLV-PGRANLVWLQKFRG---QLFAEALHL 736 Query: 317 FNNYEPLTPSKELMNQLADI-QEDYKVEDVDKEIIDQLLNEFQIVEGWDSLSQYEQRQY 374 + E PS E QE VE + + LL EG + Q+ Y Sbjct: 737 YLAGERYFPSPEDEEIYFRPEQELRLVETGVQGRLWALLTR----EGAPAAEGAAQKGY 791
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.1 bits (75), Expect = 0.004 Identities = 24/188 (12%), Positives = 56/188 (29%), Gaps = 7/188 (3%) Query: 265 RLSQGASQLNQGLSQLTQSTTLSDDKAKRIQSLEVGLPVLNQGIQQLNANLSTMQVPKLN 324 R + L ++ T + +L L + ++ + Sbjct: 121 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKT 180 Query: 325 TDELGNNLAAIAQAAQQLLVKEAAAHKEQLAVLQATSAYQSLTAEQQGELTAALTQTDKG 384 + L A ++ L A ++ A ++ A ++ +L AL Sbjct: 181 LEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALE----- 235 Query: 385 EAVAPAQTILRSVQTLSTSLQSLSQEDQSKQLEQLKEAVAQIANQSNQALPGASSALTEL 444 A+ + ++TL +L E + +LE+ E + + + + L Sbjct: 236 GAMNFSTADSAKIKTLEAEKAAL--EARQAELEKALEGAMNFSTADSAKIKTLEAEKAAL 293 Query: 445 STGLAKVN 452 A + Sbjct: 294 EAEKADLE 301
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 46.9 bits (111), Expect = 6e-09 Identities = 14/53 (26%), Positives = 28/53 (52%) Query: 4 RKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSFYTHYKDKYEMID 56 + T+Q IL + L + + +++K AG++R + Y H+KDK ++ Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 89.9 bits (223), Expect = 4e-22 Identities = 65/341 (19%), Positives = 135/341 (39%), Gaps = 22/341 (6%) Query: 37 KKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRS--QLLQLDYVLKMEESLLKGQGLAD 94 +LS+ + LA L++ E + + + + + + +++G LAD Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 95 MLSGLG--FSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRRKTVEVITYPLILLLF 152 + F ++ + G+++ L + Y Q ++R + + + YP +L + Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 153 LFVMMLGLRRYLVPQLETQNQ---------------ITYFLNHFPAFFIGFCSGLILLFG 197 ++ L +VP++ Q ++ + F + + + F Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 198 MVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMAILDIMAIE 257 + LR + + R+ + RL P +G++ + T+ YAR L + L+ + I Sbjct: 243 V-MLR-QEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 258 KSSL-MKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELEIYAQE 316 S+ + ++ EG + H + F + MI GE +L + LE A Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 317 SWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQ 357 +F SQ+ L +P + + +A ++ I AIL PI Q Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQ 401 Score = 34.8 bits (80), Expect = 5e-04 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 6/129 (4%) Query: 235 REWGTLIGQGLDLMAILDIMAIE-KSSLMKELAEDIRMSLLEGQAFHIKVATYP-FFKKE 292 R+ TL+ + L LD +A + + + +L +R ++EG + + +P F++ Sbjct: 75 RQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADAMKCFPGSFERL 134 Query: 293 LSLMIEYGEIKSKLGAELEIYA--QESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAA 350 M+ GE L A L A E +Q S++ Q +I P + VVA+ +V I + Sbjct: 135 YCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQA--MIYPCVLTVVAIAVVSILLS 192 Query: 351 ILLPIYQNM 359 +++P Sbjct: 193 VVVPKVVEQ 201
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 52.6 bits (126), Expect = 4e-12 Identities = 28/94 (29%), Positives = 50/94 (53%), Gaps = 4/94 (4%) Query: 9 RHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELS 68 K +GFTLLE+++VI++I VL L VPNL K++ + + + +EN ++Y+L Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLD 62 Query: 69 QGSKPSLSQ-LKA--DGSITEKQEKAY-QDYYDK 98 P+ +Q L++ + Y ++ Y K Sbjct: 63 NHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIK 96
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 26.9 bits (59), Expect = 0.035 Identities = 17/71 (23%), Positives = 25/71 (35%), Gaps = 9/71 (12%) Query: 37 LLKRSHYLARHDQDNWLLFSHQL--REELSGARFYKVADNK-LYVEKGKKVLAFGQFKSH 93 K S ++ D D ++ R ++ +Y VA N YV KV G + Sbjct: 217 TFKYSGWVESSDNDEHYDPGKRITYRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRV 276 Query: 94 DFRKSASNGKG 104 N KG Sbjct: 277 T------NKKG 281
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 500 bits (1288), Expect = e-179 Identities = 209/401 (52%), Positives = 281/401 (70%), Gaps = 7/401 (1%) Query: 3 KTIAINAGSSSLKWQLYQMPEEAVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTE 62 K + IN GSSSLK+QL + + VLA+G+ ERIG+ DS+ T +G+K + D+ DH + Sbjct: 2 KILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKD 61 Query: 63 AVKILLNDLI--HFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEHIEELSVLAPL 120 A+K++L+ L+ +G+I EI VGHRVV GGE F SV++ D VL+ I + LAPL Sbjct: 62 AIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121 Query: 121 HNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGT 180 HNP GI+A I+PD+ V VFDT+FH +M + YLYPIP +YYT YK+RKYG HGT Sbjct: 122 HNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGT 181 Query: 181 SHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRS 240 SHKYV+Q AA++L +P+E LK+IT H+GNG SI A +GKS+DTSMGFTPL G MGTRS Sbjct: 182 SHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRS 241 Query: 241 GDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDI-EAGLQEDNPDAV 299 G IDP+II YL+E+ E A +VVN+LNKKSG+ G+SGISSD RD+ +A + + A Sbjct: 242 GSIDPSIISYLMEK--ENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQ 299 Query: 300 LAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKN 359 LA N+F R+KK IG Y A + G D +VFTAG+GEN P +R+ ++ GL + G +D EKN Sbjct: 300 LALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKN 359 Query: 360 -VFGYRGDISTPESKVKVLVISTDEELCIARDVERL-KNTK 398 V G IST +SKV V+V+ T+EE IA+D E++ ++ K Sbjct: 360 KVRGEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIVESLK 400
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 37.1 bits (86), Expect = 1e-04 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 8/87 (9%) Query: 36 GVTRDRIYATGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEG 95 G+T + +W N + ++IDT G D F+ ++ ++ D + ++S K+G Sbjct: 53 GITIQTGITSFQWENTKVNIIDTPGHMD----FLAEVYR----SLSVLDGAILLISAKDG 104 Query: 96 VTDADEYVSKILYRTNTPVILAVNKVD 122 V + L + P I +NK+D Sbjct: 105 VQAQTRILFHALRKMGIPTIFFINKID 131
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 31.3 bits (71), Expect = 0.008 Identities = 16/55 (29%), Positives = 24/55 (43%), Gaps = 9/55 (16%) Query: 304 IINDTII--IDDFA-----HHPTEIVATIDAARQKYPSKEIVAIFQPHTFTRTIA 351 +I D ++ I D H+P I I A Q P +VA+F F +T+ Sbjct: 103 LITDDVLKAITDCIELAPLHNPANIEG-IKACTQIMPDVPMVAVFDT-AFHQTMP 155
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.8 bits (72), Expect = 7e-04 Identities = 26/120 (21%), Positives = 45/120 (37%), Gaps = 29/120 (24%) Query: 46 VALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVGTAL 105 + ++ +G I+ + N GY I +++AK ++++GVGTAL Sbjct: 69 LYYLENNCIGRIK----------------IRSN--WNGYALIEDIAVAKDYRKKGVGTAL 110 Query: 106 LAALKDLVVAQQRTGLILTCHDYLIS---YYEMNGFINQGISESQHGGT--------LWY 154 L + GL+L D IS +Y + FI + + WY Sbjct: 111 LHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSNFPTANEIAIFWY 170
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 136 bits (344), Expect = 2e-38 Identities = 68/231 (29%), Positives = 113/231 (48%), Gaps = 22/231 (9%) Query: 38 WEFLGKPMSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQS-EKMTFL 96 F+ +P+ + + + G +G +III+T IVR ++ PL KA Y S KM L Sbjct: 333 LWFISQPLFKLLKWIHSFVG-NWGFSIIIITFIVRGIMYPLT-----KAQYTSMAKMRML 386 Query: 97 KPVFEPINKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFA 156 +P + + +R+ ++K E+MA +A +NPLGG C PLLIQMP F A+Y+ Sbjct: 387 QPKIQAMRERLG-----DDKQRISQEMMALYKAEKVNPLGG--CFPLLIQMPIFLALYYM 439 Query: 157 AQYTKGVSTSTFM----SIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMY 212 + + + F + +L ++ FF +S V++ + +M Sbjct: 440 LMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPM---QQKIMT 496 Query: 213 TMPIMMIFMSFSLPAGVGLYWLVGGFFSIIQQ-LITTYLLKPRLHKQIKEE 262 MP++ P+G+ LY++V +IIQQ LI L K LH + K++ Sbjct: 497 FMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKK 547
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 97.1 bits (241), Expect = 7e-25 Identities = 46/123 (37%), Positives = 65/123 (52%), Gaps = 8/123 (6%) Query: 23 SLTAAQAILESGWGKHA-------PHNALFGIKADASWTGKSFNTKTQEEYQAGVITDIV 75 L AQA LESGWG+ P LFG+KA +W G T E Y+ G + Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230 Query: 76 DRFRAYDSWDESIADHGQFLVDNPRYQSVIGEADYKKACHAIKDAGYATASGYAELLIQI 135 +FR Y S+ E+++D+ L NPRY +V A ++ A++DAGYAT YA L + Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290 Query: 136 IEE 138 I++ Sbjct: 291 IQQ 293
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 171 bits (435), Expect = 4e-55 Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 28/254 (11%) Query: 6 IIKIVFIITVILISTISPIIKSDSKKDISNVKSDLLYAYTITPYDYKDCRVNFSTT---- 61 +I I +I VI + + D D + S+ Y Y D V+ + Sbjct: 10 VILIFALILVISTPNVLAESQPDPMPDDLHKSSEFTGTMGNMKYLYDDHYVSATKVKSVD 69 Query: 62 ----HTL--NIDTQKYRGKDYYISSEMSYEASQKFKRDDHVDVFGLFYILNSHTGEY--- 112 H L NI +K + D + ++ + ++K+K D+ VDV+G Y +N + Sbjct: 70 KFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYK-DEVVDVYGSNYYVNCYFSSKDNV 128 Query: 113 ---------IYGGITPAQNNKVNHKLLGNLFIS-GESQQN-LNNKIILEKDIVTFQEIDF 161 +YGGIT + N ++ L N+ + E+++N ++ ++ +K VT QE+D Sbjct: 129 GKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTAQELDI 188 Query: 162 KIRKYLMDNYKIYD-ATSPYVSGRIEIGTKDGKHEQIDLFDSPNEG-TRSDIFAKYKDNR 219 K R +L++ +Y+ +SPY +G I+ +G D+ +P + +S Y DN+ Sbjct: 189 KARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNK 248 Query: 220 IINMKNFSHFDIYL 233 ++ K+ +++L Sbjct: 249 TVDSKS-VKIEVHL 261
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 47.4 bits (113), Expect = 5e-08 Identities = 42/191 (21%), Positives = 79/191 (41%), Gaps = 16/191 (8%) Query: 170 RKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVASMRAQELQYTNI 229 R++ + AG + +I P+A A G+ V+D+GGG T VA + + Y++ Sbjct: 127 RESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSS 186 Query: 230 YAEGGEYITKDISKVLKTSLAI------AEALKFNFGQAEISEASITETVK-VDVV-GSE 281 GG+ + I ++ + AE +K G A + V+ ++ G Sbjct: 187 VRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVP 246 Query: 282 EPVEVTERYLSEIISARIRHILDRVKQDLER------GRLLDLPGGIVLIGGGAIMPGVV 335 + + E + + I+ V LE+ + + G+VL GGGA++ + Sbjct: 247 RGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISE--RGMVLTGGGALLRNLD 304 Query: 336 EIAQEIFGVTV 346 + E G+ V Sbjct: 305 RLLMEETGIPV 315
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 30.7 bits (69), Expect = 0.010 Identities = 19/99 (19%), Positives = 31/99 (31%), Gaps = 10/99 (10%) Query: 154 FEQEDQLSKVKHLGAVTKVFKDANQMPESTQLE-AVKEYFSRDLKTLLFIGGSAGAHVFN 212 FE ++K + + N + S+ E A S K + G Sbjct: 83 FEALKAINKQTGI--------EINNVEPSSNFESAYNSALSAGHKIWVLNGFKHQQS-IK 133 Query: 213 QFISDHPELKQRYNIINITGDPHLNELSSHLYRVDYVTD 251 Q+I H E +R I I D + Y + + Sbjct: 134 QYIDAHREELERNQIKIIGIDFDIETEYKWFYSLQFNIK 172
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 186 bits (473), Expect = 4e-53 Identities = 102/477 (21%), Positives = 187/477 (39%), Gaps = 97/477 (20%) Query: 8 IRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQE--RAMDSNDLEKERGITILAKNTA 65 I N+ ++AHVD GKTTL + LL S + E + + D+ LE++RGITI T+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 66 VAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQNLI 125 + + ++NI+DTPGH DF EV R + ++DG +L++ A +G QTR + + + Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 126 PIVVVNKIDKPSARP-------------------------------------AEVVDEVL 148 I +NKID+ + V E Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182 Query: 149 ELFIELGADDEQLE-----------------FPVVYASAINGTSSLSDDPADQEHTMAPI 191 + +E + LE FPV + SA N + + Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIG------------IDNL 230 Query: 192 FDTIIDHIPAPVDNSDEPLQFQVSLLDYNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTT 251 + I + + L +V ++Y++ R+ R++ G + + D V +S Sbjct: 231 IEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRIS----EK 286 Query: 252 KNFRVTKLFGFFGLERREIQEAKAGDLIAVSGMEDIFVGETITPTDCVEALPILRIDEPT 311 + ++T+++ E +I +A +G+++ + E + + + T + + P Sbjct: 287 EKIKITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPL 345 Query: 312 LQMTFLVNNSPFAGREGKWITSRKVEER--LLAELQT----DVSLRVDPTDSPDKWTVSG 365 LQ T + K ++R LL L D LR + + +S Sbjct: 346 LQTT---------------VEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSF 390 Query: 366 RGELHLSILIETMRRE-GYELQVSRPEVIIKEIDGVKCEPFERVQIDTPEEYQGAII 421 G++ + + ++ + E+++ P VI E K E + I+ P A I Sbjct: 391 LGKVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAE--YTIHIEVPPNPFWASI 445 Score = 42.5 bits (100), Expect = 4e-06 Identities = 18/79 (22%), Positives = 31/79 (39%), Gaps = 1/79 (1%) Query: 403 EPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPARGLIGYSTEFLS 462 EP+ +I P+EY + +++D Q + N + L IPAR + Y ++ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRSDLTF 595 Query: 463 MTRGYGIMNHTFDQYLPVV 481 T G + Y Sbjct: 596 FTNGRSVCLTELKGYHVTT 614
>PF03309#Bvg accessory factor Length = 271 Score = 31.7 bits (72), Expect = 0.003 Identities = 29/126 (23%), Positives = 43/126 (34%), Gaps = 14/126 (11%) Query: 5 LLGIDLGGTTIKFGILTAAGEVQE---KWAIETNILEGGKHIVPDIIASIKHRLDLYGLS 61 LL ID+ T G+++ +G+ + +W I T + D +A L G Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTE-----PEVTADELALTIDG--LIGDD 54 Query: 62 SADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVEKELGIPFAIDNDANVAALG 121 + G S V + V W V GIP +DN V A Sbjct: 55 AERLTGASGLS--TVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVGA-- 110 Query: 122 ERWVGA 127 +R V Sbjct: 111 DRIVNC 116
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 47.8 bits (113), Expect = 2e-07 Identities = 36/205 (17%), Positives = 69/205 (33%), Gaps = 17/205 (8%) Query: 461 LTKESDETKKLKKEQEGLVESNKQLRDSVREGVQERKKGLESVKESTAAHQKLADEIIKL 520 T +S + K L+ E+ L L + + + +A + L E L Sbjct: 136 STADSAKIKTLEAEKAALAARKADLE-------KALEGAMNFSTADSAKIKTLEAEKAAL 188 Query: 521 AAKENKTAGEKRNLKNKIDELNGSIDGLNLAYDKNSNSLSHNADQIKSRISAMEAESTWQ 580 A++ + N + I L + + ++ + S Sbjct: 189 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKA----DLEKALEGAMNFS--- 241 Query: 581 TAQQNLLNIEQKRSEVSKKLAENAELRKKWNEEANVSDSVRKEKIAELTEEEAKLKNMQT 640 + I+ +E + A AEL K E A + KI L E+A L+ + Sbjct: 242 --TADSAKIKTLEAEKAALEARQAELEKA-LEGAMNFSTADSAKIKTLEAEKAALEAEKA 298 Query: 641 QLQEEYNKTSATQQAAADAMAAAEE 665 L+ + +A +Q+ + A+ E Sbjct: 299 DLEHQSQVLNANRQSLRRDLDASRE 323 Score = 30.8 bits (69), Expect = 0.036 Identities = 43/240 (17%), Positives = 77/240 (32%), Gaps = 33/240 (13%) Query: 461 LTKESDETKKLKKEQEGLVESNKQLRDSVREGVQERKKGLESVKESTAAHQKLADEIIKL 520 T +S + K L+ E+ L L ++ + +K A L +L Sbjct: 206 STADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAEL 265 Query: 521 AAKENKTAGEKRNLKNKIDELNGSIDGL----------NLAYDKNSNSLSHNADQIKSRI 570 KI L L + + N SL + D + Sbjct: 266 EKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAK 325 Query: 571 SAMEAESTWQTAQQNLLNIEQKRSEVSKKLAENAELRK-------KWNEEANVSDSVR-- 621 +EAE Q ++ E R + + L + E +K K E+ +S++ R Sbjct: 326 KQLEAEH--QKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQS 383 Query: 622 -----------KEKI-AELTEEEAKLKNMQTQLQEEYNKTSATQQAAADAMAAAEESGSA 669 K+++ L E +KL ++ +E T++ A+ A E A Sbjct: 384 LRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKA 443
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 28.6 bits (64), Expect = 0.040 Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Query: 264 LASVATSIVGVVSFLGL---IVPHMSRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLA 320 + S A + +GL H S+L++ Q +PFS L V + L Sbjct: 29 VVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQSYLPFSQALSYVVDNVLLEFF-YLC 87 Query: 321 YPLEISPAIIMSIVGG 336 +PL ++ A +M+I Sbjct: 88 FPL-LTVAALMAIASH 102
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 69.6 bits (170), Expect = 8e-16 Identities = 54/265 (20%), Positives = 103/265 (38%), Gaps = 24/265 (9%) Query: 29 VACVNQHPKTAKETEQQRIVATSVAVVDICDRLNLDLVGVCDSKLYTL----PKRYDAVK 84 + A + RIVA V++ L + GV D+ Y L P D+V Sbjct: 20 PLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVI 79 Query: 85 RVGLPMNPDIELIASLKPTWILSPNSLQEDLEPKYQKLDTEYGFLNLRSVEG------MY 138 VGL P++EL+ +KP++++ P + L +G Sbjct: 80 DVGLRTEPNLELLTEMKPSFMV----WSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMAR 135 Query: 139 QSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAKRKGK-KKPKVLILMGLPGSYLVATNQS 197 +S+ ++ +L Q A+ QY+D+ R+ + + + +P +L + P LV S Sbjct: 136 KSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNS 195 Query: 198 YVGNLLDLAGGENVYQ--SDEKEFLSVNPEDMLA-KEPDLILRTAHAIPDKVKVLFDKEF 254 +LD G N +Q ++ +V+ + + A K+ D++ D + Sbjct: 196 LFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDAL------ 249 Query: 255 AENDIWKHFTAVKEGKVYDLDNTLF 279 +W+ V+ G+ + F Sbjct: 250 MATPLWQAMPFVRAGRFQRVPAVWF 274
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 347 bits (891), Expect = e-121 Identities = 121/368 (32%), Positives = 194/368 (52%), Gaps = 23/368 (6%) Query: 7 RPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQVSKALLPQVDGYCVSN 66 RP A ++LQA+K+N++ V++ + ++VVKA+AYGHG ++ A+ DG+ + N Sbjct: 3 RPIQASLDLQALKQNLSIVRQAAT-HARVWSVVKANAYGHGIERIWSAI-GATDGFALLN 60 Query: 67 LDEALQLRQAGIDKEILIL-GVLLPNELELAVANAITVTIAS---LDWIALARLEKKECQ 122 L+EA+ LR+ G IL+L G +LE+ + +T + S L + ARL+ Sbjct: 61 LEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAP--- 117 Query: 123 GLKVHVKVDSGMGRIGLRSSKEVNLLIDSLKELGADVEGIFTHFATADEADDTKFNQQLQ 182 L +++KV+SGM R+G + + + + + +HFA A+ D + Sbjct: 118 -LDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGIS--GAMA 174 Query: 183 FFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVRLGIVSYGLNPSGSN-LSLPFPLQE 241 ++ GL SNSA ++WH + F+ VR GI+ YG +PSG L+ Sbjct: 175 RIEQAAEGL---ECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRP 231 Query: 242 ALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNM-QGFSVLVDGQ 300 ++L S ++ V+ + AG+ VGYG YTA+ + +G V GYADG+ R+ G VLVDG Sbjct: 232 VMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGV 291 Query: 301 FCEIIGRVSMDQLTIRLSKA--YPLGTKVTLIGSNQQKNISTTDIANYRNTINYEVLCLL 358 +G VSMD L + L+ +GT V L G K I D+A T+ YE++C L Sbjct: 292 RTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWG----KEIKIDDVAAAAGTVGYELMCAL 347 Query: 359 SDRIPRIY 366 + R+P + Sbjct: 348 ALRVPVVT 355
>SECA#SecA protein signature. Length = 901 Score = 1052 bits (2723), Expect = 0.0 Identities = 394/903 (43%), Positives = 560/903 (62%), Gaps = 73/903 (8%) Query: 1 MANILRKVIENDKG-ELRKLEKIAKKVESYADQMASLSDRDLQGKTLEFKERYQKGETLE 59 + +L KV + LR++ K+ + + +M LSD +L+GKT EF+ R +KGE LE Sbjct: 2 LIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLE 61 Query: 60 QLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNAI 119 L+PEAFAVVREA+KRV G+ + VQ++GG+VL+ + EMRTGEGKTLTAT+P YLNA+ Sbjct: 62 NLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL 121 Query: 120 AGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKSPAEKREAYNCDITYSTNSE 179 G+GVHV+TVN+YL+ RDA ++ +LGL+VGINL KREAY DITY TN+E Sbjct: 122 TGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNE 181 Query: 180 VGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRAD 239 GFDYLRDNM E+ VQR L++ALVDEVDS+LIDEARTPLI+SG + ++Y R + Sbjct: 182 YGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSS-EMYKRVN 240 Query: 240 MFVKTLT------------SVDYVIDVPTKTIGLSDSGIDKAESYFNLS-------NLYD 280 + L + +D ++ + L++ G+ E +LY Sbjct: 241 KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS 300 Query: 281 IENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGLHQAIEA 340 N+ L H + ALRA+ + D+DY+V +DGE++IVD+ TGRTM+GRR+SDGLHQA+EA Sbjct: 301 PANIMLMHHVTAALRAHALFTRDVDYIV-KDGEVIIVDEHTGRTMQGRRWSDGLHQAVEA 359 Query: 341 KEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIA 400 KEGV+IQ E++T ASIT+QN FR+Y+KLAGMTGTA TE EF +Y + + +PTNRP+ Sbjct: 360 KEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMI 419 Query: 401 RIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKLVEAGIPHEVL 460 R D DL+Y T K +A++ED+K R AKGQP+LVGT+++E S+L+S +L +AGI H VL Sbjct: 420 RKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVL 479 Query: 461 NAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLG----------------------- 497 NAK H EA I+ AG AVTIATNMAGRGTDI LG Sbjct: 480 NAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKA 539 Query: 498 ------EGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFG 551 + V E GGL +IGTERHESRRIDNQLRGRSGRQGD G S+FYLS+ED LMR F Sbjct: 540 DWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFA 599 Query: 552 SDRIKAFLDRMKLDEEDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREI 611 SDR+ + ++ + + I+ + + + +AQ++VE N+D RKQ+L+YDDV +QR Sbjct: 600 SDRVSGMMRKLGM-KPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRA 658 Query: 612 IYANRRDVITANRDLGPEIKAMIKRTIDRAVDAHARSNR---KDAIDAIVTFARTSLVPE 668 IY+ R +++ + D+ I ++ + +DA+ I + + + Sbjct: 659 IYSQRNELLDVS-DVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLD 717 Query: 669 ESIS--AKELRGLKDDQIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWT 726 I+ + L ++ ++E++ +++ +Y ++ + E + F+K ++L +D+ W Sbjct: 718 LPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVG-AEMMRHFEKGVMLQTLDSLWK 776 Query: 727 EHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIH-EQE 785 EH+ A+D LR + LRGYAQ +P EY+ E F MF M+ +++++V T+ K Q+ +E Sbjct: 777 EHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEE 836 Query: 786 RERASQRATTAAPQNIQSQQSANTDD-------------LPKVERNEACPCGSGKKFKNC 832 E Q+ A + Q QQ ++ DD KV RN+ CPCGSGKK+K C Sbjct: 837 VEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQC 896 Query: 833 HGR 835 HGR Sbjct: 897 HGR 899
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.024 Identities = 9/16 (56%), Positives = 12/16 (75%) Query: 45 IIGASGSGKSLLAHAI 60 I G SG+GK L+A A+ Sbjct: 165 ITGESGTGKELVARAL 180
>PF05043#Transcriptional activator Length = 493 Score = 539 bits (1390), Expect = 0.0 Identities = 108/491 (21%), Positives = 218/491 (44%), Gaps = 16/491 (3%) Query: 16 RELKLISYLTENSNAIGVKDKELSKALNISMLTLQSCLTNMQFMKEVGGITYKDGYINIW 75 R+L+L+ L E+ EL++ LN + ++ L++++ I I Sbjct: 11 RQLELLELLFEHKRWFHRS--ELAELLNCTERAVKDDLSHVKSAFPDLIFHSSTNGIRII 68 Query: 76 YHQCCGLQEVYQKALRESPSLKLLELLFFRDFSSLEELAEELFVSLSTLKRLIKKTNTYL 135 ++ VY + S +LE +FF + E + +E ++S S+L R+I + N + Sbjct: 69 NTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRIISQINKVI 128 Query: 136 SHTFAISIVTSPVQVSGDERQIRLFYLKYFSEAYKISEWPFGDILNLKNCERLLSLLIKE 195 F + +PVQ+ G+ER IR F+ +YFSE Y EWPF + + + +LL L+ KE Sbjct: 129 KRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFEN-FSSEPLSQLLELVYKE 187 Query: 196 VDVKVHFTLFQHLKILSGVNLIRYYKGYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYL 255 ++ + + LK+L NL R G+ + + + + + I+ +++ F Sbjct: 188 TSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEGVAQSFES 247 Query: 256 KFGLHLDEYTIAEMFSNHLNDKLEIGCAFEIIDQDPTSGGRQVTNWIHLL----DEMEIK 311 ++ + LDE + ++F ++ I E + V HLL D++ +K Sbjct: 248 EYNISLDEEVVCQLFVSYFQKMFFID---ESLFMKCVKKDSYVEKSYHLLSDFIDQISVK 304 Query: 312 LNLSITNKYEVAVTLHNASVLNEEDITANYLLFDYKKSYLNFYQKEHPRIYEPFVTSVEK 371 + I NK + LHN + L +++ ++LFD K + + +Q P+ + Sbjct: 305 YQIEIENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDVKKELSH 364 Query: 372 LMQADNAQVSKELINQLTYCFFITWENSFLKVNQKDEKVRLLVI----ERSYNSVGNFLK 427 ++ S ++N L+Y F ++ + + Q K+++LV+ + V L Sbjct: 365 YLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLS 424 Query: 428 KYIGEFFSITNFDELDCLTIDLVEIEKQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDR 487 Y F + + EL+ L + YD+I+++ ++ E + + + ++I Sbjct: 425 YYCSNNFELEVWTELELSKESLE--DSPYDIIISNFIIPPIENKRLIYSNNINTVSLIYL 482 Query: 488 LNEFLNVSFTD 498 LN + + + Sbjct: 483 LNAMMFIRLDE 493
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.4 bits (76), Expect = 0.002 Identities = 14/90 (15%), Positives = 26/90 (28%), Gaps = 3/90 (3%) Query: 108 TKQPDSSDQSTPSPKDQSSQKE-SQNKDGRPTPSPDQQKDQTPDKTPEKSADKTPEKGPE 166 + + + P + + + +P P P + + P+ PE + E Sbjct: 38 HQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVI--E 95 Query: 167 KSAKKTPEPNRDAPKPIQPPLAAAAPVFAP 196 K K + K QP P Sbjct: 96 KPKPKPKPKPKPVKKVEQPKRDVKPVESRP 125 Score = 33.0 bits (75), Expect = 0.002 Identities = 19/84 (22%), Positives = 30/84 (35%), Gaps = 6/84 (7%) Query: 139 PSPDQQKD---QTPDKTPEK---SADKTPEKGPEKSAKKTPEPNRDAPKPIQPPLAAAAP 192 P+P Q P P PE + PEP ++AP I+ P P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 103 Query: 193 VFAPWRESDKDLSKLKPSSRSSAA 216 P ++ ++ +KP A+ Sbjct: 104 KPKPVKKVEQPKRDVKPVESRPAS 127 Score = 33.0 bits (75), Expect = 0.002 Identities = 14/94 (14%), Positives = 23/94 (24%), Gaps = 4/94 (4%) Query: 104 DKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSADKTPEK 163 + P T ++ P P+ + + P+ E K Sbjct: 39 QVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK 98 Query: 164 GPE----KSAKKTPEPNRDAPKPIQPPLAAAAPV 193 K KK +P RD P + Sbjct: 99 PKPKPKPKPVKKVEQPKRDVKPVESRPASPFENT 132
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 32.1 bits (73), Expect = 0.002 Identities = 14/62 (22%), Positives = 28/62 (45%), Gaps = 8/62 (12%) Query: 10 VINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKREFDQTSKQIKGKTVTEIRDILTKKI 69 V + LI+ ++ A+ + + KE +K+ +TEIRD+L ++ Sbjct: 82 VFDFLIVA------FAIFMAIKLINKLNRKKEEPAAAPAPTKEEV--LLTEIRDLLKEQN 133 Query: 70 NK 71 N+ Sbjct: 134 NR 135
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 1e-20 Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 1/128 (0%) Query: 3 KILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLE 62 ILV +DD I V+ + L YD + DL++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 VLKTIRKT-SDVPIIMLTALDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTP 121 +L I+K D+P+++++A + T + + DY+ KPF LI I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 DEKRQIGD 129 + D Sbjct: 125 RPSKLEDD 132
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 54.4 bits (131), Expect = 4e-10 Identities = 34/144 (23%), Positives = 55/144 (38%), Gaps = 10/144 (6%) Query: 60 DISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQPLFSYETSQRLTAQSSEF 119 +I T G++T + SK VK++ VK+G+ V+ G L +LTA +E Sbjct: 81 EIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLL------KLTALGAEA 134 Query: 120 DVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESLLEQIRSAEDSVSQAL 179 D + Q + A L+ Y I K PDE + + E +L Sbjct: 135 DTL----KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190 Query: 180 SDAKTADSDVKTAQIELDKANATA 203 + + + Q EL+ A Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRA 214 Score = 39.4 bits (92), Expect = 2e-05 Identities = 28/180 (15%), Positives = 61/180 (33%), Gaps = 16/180 (8%) Query: 120 DVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESL---LEQIRSAEDSVS 176 D + ++ +AK + Y VNE+ KS+ E L E + + Sbjct: 239 DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN 298 Query: 177 QALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKS 236 + L + ++ +EL K + + +++ + + L Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEE-------RQQASVIRAPVSVKVQQLKVHTEGGVV- 350 Query: 237 KKENETFMEII-DKSKMLVKGNISEFDRDKLKIGQKVEV-IDRKDNSK--KWTGKVTQVG 292 ET M I+ + + V + D + +GQ + ++ ++ GKV + Sbjct: 351 -TTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN 409