>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.0 bits (75), Expect = 2e-04 Identities = 17/107 (15%), Positives = 36/107 (33%), Gaps = 5/107 (4%) Query: 37 LLHKHAFWAQQRDTSELKKMLAGSNVVISLWR-GKRLVGFGRATSDGIYRAVLWDVVVAG 95 ++ Q D + L+ +G + S+ A++ D+ VA Sbjct: 40 ERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAK 99 Query: 96 DLQGHGLGRQVIEALLIAPGIRNVERVYLMTTNSR----GFYEQMGF 138 D + G+G ++ + + + L T + FY + F Sbjct: 100 DYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>SECA#SecA protein signature. Length = 901 Score = 797 bits (2061), Expect = 0.0 Identities = 294/561 (52%), Positives = 367/561 (65%), Gaps = 20/561 (3%) Query: 1 MLKLLLGDPNARKLKRYQPIVTDINILEEDIALLSDDQLRSKTADFRQQFENVVSFAKQR 60 +L + G N R L+R + +V IN +E ++ LSD++L+ KTA+FR + E Sbjct: 5 LLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEV----- 59 Query: 61 ALLDELLPEAFAVVREAAKRVLGMRHFDVQLIGGMVLHEGQIGEMKTGEGKTLVATLPSY 120 L+ L+PEAFAVVREA+KRV GMRHFDVQL+GGMVL+E I EM+TGEGKTL ATLP+Y Sbjct: 60 --LENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAY 117 Query: 121 LNALTGRGVHVVTVNDYLARRDAEWMGQVHRFLGLSVGLIQQDMSPAERRRNYACDITYA 180 LNALTG+GVHVVTVNDYLA+RDAE + FLGL+VG+ M +R YA DITY Sbjct: 118 LNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYG 177 Query: 181 TNSELGFDYLRDNMATDLSEVVQREFQYCVIDEVDSILIDEARTPLIISGQVERPQEKYQ 240 TN+E GFDYLRDNMA E VQR+ Y ++DEVDSILIDEARTPLIISG E E Y+ Sbjct: 178 TNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYK 237 Query: 241 QAADVAAALERAAEQGKDGIDPEGDYEVDEKQRSCTLTDEGFAKAEQNLRVRDLFDPAD- 299 + + L R ++ + EG + VDEK R LT+ G E+ L + D + Sbjct: 238 RVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGES 297 Query: 300 -------PWAHYITNALKAKELFVRDVNYIVRDGEAVIVDEFTGRVMPGRRWSDGQHQAI 352 H++T AL+A LF RDV+YIV+DGE +IVDE TGR M GRRWSDG HQA+ Sbjct: 298 LYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAV 357 Query: 353 EAKEQLAIQPETQTLASITYQNFFLLYPRLAGMTGTAKTEEVEFEKTYKLETSVIPTNQP 412 EAKE + IQ E QTLASIT+QN+F LY +LAGMTGTA TE EF YKL+T V+PTN+P Sbjct: 358 EAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRP 417 Query: 413 RARADWVDQVYKTESAKWRAVANETAEIHKQGRPVLVGTTSVEKSELLSSLLSEQEIPHN 472 R D D VY TE+ K +A+ + E +G+PVLVGT S+EKSEL+S+ L++ I HN Sbjct: 418 MIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHN 477 Query: 473 LLNAKPENVEREAEIVAQAGRAGAVTIATNMAGRGTDIILGGNSDYMARLKLREVLLPRL 532 +LNAK EA IVAQAG AVTIATNMAGRGTDI+LGG+ + A + E Sbjct: 478 VLNAKFH--ANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGS--WQAEVAALENPTAEQ 533 Query: 533 VRPEEGHRPPVPLQRAAETGG 553 + + V E GG Sbjct: 534 IE-KIKADWQVRHDAVLEAGG 553 Score = 405 bits (1041), Expect = e-129 Identities = 124/317 (39%), Positives = 185/317 (58%), Gaps = 5/317 (1%) Query: 627 DDAQIAALRESIARVKTEYDVVVTQEEVRVREAGGLHVIGTERHESRRVDNQLRGRAGRQ 686 A++AAL A + V EAGGLH+IGTERHESRR+DNQLRGR+GRQ Sbjct: 519 WQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQ 578 Query: 687 GDLGSTRFFLSLEDNLLRIFGGERVASLMNAFRVEEDMPIESGMLTRSLEGAQKKVETYY 746 GD GS+RF+LS+ED L+RIF +RV+ +M ++ IE +T+++ AQ+KVE+ Sbjct: 579 GDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRN 638 Query: 747 YDIRKQVFEYDEVMNNQRRAVYAERRRVLEGRGLKKQVIGYGERTMDDIVEAYVNPDLPP 806 +DIRKQ+ EYD+V N+QRRA+Y++R +L+ + + + E ++AY+ P Sbjct: 639 FDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLE 698 Query: 807 EEWDLGQLVSKVQQFVYLLEDLKP--EQLQGLSMEELKSFLQEQLRNAYDIKEGQIEQQR 864 E WD+ L +++ L + ++ L E L+ + Q Y KE + Sbjct: 699 EMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVV---G 755 Query: 865 PGLMREAERFFILQQIDTLWREHLQAMDALRESVGLRGYGQKDPLIEYKNEGYDMFLEMM 924 +MR E+ +LQ +D+LW+EHL AMD LR+ + LRGY QKDP EYK E + MF M+ Sbjct: 756 AEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAML 815 Query: 925 ANMRRNVIYSMFMFQPA 941 +++ VI ++ Q Sbjct: 816 ESLKYEVISTLSKVQVR 832
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 195 bits (496), Expect = 2e-62 Identities = 88/328 (26%), Positives = 143/328 (43%), Gaps = 31/328 (9%) Query: 1 MKAVVVGASGFIGSHLVDALLAQGSQVRAL----SRHLPGL--ITPKAQDHPGLVLHPLD 54 MK +V GA+GFIG H+ LL G QV + + L + PG H +D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 55 MADRLGLEK--ALVGSEIIFHLASGSLPQSSNRNPREDININVLGALNLLEASLEVGIQK 112 +ADR G+ A E +F + S NP + N+ G LN+LE IQ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 113 FVFVSSGGTVYGIPKQVPIAENHPTD-PICSYGITKLAIEKYVSLYRHLYGLNSTVVRLA 171 ++ SS +VYG+ +++P + + D P+ Y TK A E Y HLYGL +T +R Sbjct: 121 LLYASSS-SVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 172 NPYGERQRLDSCQGVVPVFLNRALRSEPLEIWGDGSTIRDFLYITDVVQALLAISHY--- 228 YG R D + F L + ++++ G RDF YI D+ +A++ + Sbjct: 180 TVYGPWGRPDM---ALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPH 236 Query: 229 ---------------KGPENLFNVGSGIGLSLCELVKLIENELGRPLQVSYQQSRTFDVP 273 P ++N+G+ + L + ++ +E+ LG + + + DV Sbjct: 237 ADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVL 296 Query: 274 TNVLSIKRARNCLGWSPKVCANDGIHRF 301 K +G++P+ DG+ F Sbjct: 297 ETSADTKALYEVIGFTPETTVKDGVKNF 324
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 40.7 bits (95), Expect = 7e-06 Identities = 55/251 (21%), Positives = 90/251 (35%), Gaps = 30/251 (11%) Query: 64 QLAKISNAADVYFQRVYDSTNTDISF-YYDTTIDLGDPSVTTFGVAVPNNNGGRQWTEIF 122 L S+ A++ F V + + +I+F Y T P N G + Sbjct: 108 SLQSWSDVANLTFTEVTGNKSANITFGNYTRDASGNLDYGTQAYAYYPGNYQGAGSSWYN 167 Query: 123 LNGPEIQAKSEDFSNY---VFNHELGHALGLEHPHD--NSDGDVYLSTDPQLSATPEETV 177 N I ++ Y F HE+GHALGL HP + +GD + + + ++ Sbjct: 168 YNQSNI--RNPGSEEYGRQTFTHEIGHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQFSI 225 Query: 178 MSYRVPE------SGVYPTDFSINDYNALEQIWGSPQAQSTQNVVYRLYQQSTGRHLFSA 231 MSY +G Y I+D A+++++G+ T + VY + +T R Sbjct: 226 MSYWGENETGADYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYG-FNSNTDR----- 279 Query: 232 NLTEVDILTGGNSSDYLNEGIAYQVQEGADQDLYRFFQPSTGLHFYSANSDERDNLINSN 291 D T +SS L + V + D + F S D + Sbjct: 280 -----DFYTATDSSKAL----IFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSD-VGGLK 329 Query: 292 QSGYIYEGVAY 302 + I GV Sbjct: 330 GNVSIAHGVTI 340
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 185 bits (472), Expect = 1e-55 Identities = 104/446 (23%), Positives = 184/446 (41%), Gaps = 41/446 (9%) Query: 38 MRKRLDKITPNA-SYENDF----------PSRRWPLILLTSLSGFVGILLVWSLIARSEI 86 +RK+LD TP EN+F P R P ++ + GF+ I + S++ + EI Sbjct: 25 IRKQLD--TPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEI 82 Query: 87 SVDTQGRLRPSQTPTTSRAFSLTTSSTIFVKEGDFVQKGQPIMQLDDESLKSKLLALENR 146 G+L S + + I VKEG+ V+KG +++L ++ L ++ Sbjct: 83 VATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSS 142 Query: 147 YS---------KIYVELQETSRFIGLNFPSDLPKPKLSYSLDLSVVRSSLEFINTQKEKV 197 +I E ++ L P + +S L + E +T + + Sbjct: 143 LLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQK 202 Query: 198 AQLEARLEQLLVKHKSLEQNI--KLQSIIVEKHE-----RLLNSGAIAELQVLQQSQKLQ 250 Q E L++ + ++ I VEK LL+ AIA+ VL+Q K Sbjct: 203 YQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYV 262 Query: 251 DLKSELESNQQDQIRTRAALRESGSEFTGRNNSLYSQRISEL-------SSIYAEISSTK 303 + +EL + + + + + E+ ++ + +L + E++ + Sbjct: 263 EAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNE 322 Query: 304 DAIRNSLLRAPLTGYVFRLAVKVPGVPVRPGEELFQIIPS-ELLTASVDVPARDIGFINK 362 + + S++RAP++ V +L V G V E L I+P + L + V +DIGFIN Sbjct: 323 ERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINV 382 Query: 363 GMQVDVHIDSYPSSTYGVLKGTVKSIGRDSIEPTSPIQLPTYSIPVDVQLQKQSLVSKGK 422 G + ++++P + YG L G VK+I D+IE L I + +++ L + K Sbjct: 383 GQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRL-GLVFNVI---ISIEENCLSTGNK 438 Query: 423 YYPLKPGMTARVSFNLRTVSVFRRLF 448 PL GM SV L Sbjct: 439 NIPLSSGMAVTAEIKTGMRSVISYLL 464
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 79.1 bits (195), Expect = 1e-18 Identities = 43/197 (21%), Positives = 74/197 (37%), Gaps = 37/197 (18%) Query: 8 SIFITGATGSFGKAFISQLLTQNPHIHRAVVFSRDE--------LKQWEFQQLYPQKQYP 59 +TGA G G +LL H+ V D LKQ + L P Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAG---HQVVGI--DNLNDYYDVSLKQARLELL----AQP 52 Query: 60 QLRFFLGDIRDQTRLRR--ALEGIDTVVHAAALKQVPAAEYNPFEFIRTNVIGAQNLIEA 117 +F D+ D+ + A + V + V + NP + +N+ G N++E Sbjct: 53 GFQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEG 112 Query: 118 CLDSDVERVVALST---------------DKAAAPVNLYGATKLCSDKLFIAANNFVGSR 162 C + ++ ++ S+ D PV+LY ATK ++ + ++ G Sbjct: 113 CRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG-- 170 Query: 163 KLRFSVVRYGNVMGSRG 179 L + +R+ V G G Sbjct: 171 -LPATGLRFFTVYGPWG 186
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.1 bits (70), Expect = 0.006 Identities = 12/54 (22%), Positives = 25/54 (46%), Gaps = 2/54 (3%) Query: 460 IALDTAFRGHGLAFDVLDSGISFFVSKYSNSPTLIAEIKSNNYASQRLFYKAGF 513 IA+ +R G+ +L I + +K ++ L+ E + N ++ + K F Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEW--AKENHFCGLMLETQDINISACHFYAKHHF 146
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 420 bits (1082), Expect = e-150 Identities = 185/347 (53%), Positives = 238/347 (68%), Gaps = 10/347 (2%) Query: 2 FFRRFQLSRDIGIDLGTANTLIYVSGKGIVLQEPSVVALDLENGVP----LAVGDDAKLM 57 F F S D+ IDLGTANTLIYV G+GIVL EPSVVA+ + AVG DAK M Sbjct: 5 FRGMF--SNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQM 62 Query: 58 LGRTPGNIRAVRPLRDGVIADFDAAEQMLKTFIQKGNEGRGI-VAPRLVVGIPSGVTGVE 116 LGRTPGNI A+RP++DGVIADF E+ML+ FI++ + + +PR++V +P G T VE Sbjct: 63 LGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVE 122 Query: 117 RRAVREAGM-AGAREVHLIDEPVAAAIGAGLPVTEPIGTMIVDIGGGTTEVAVLSLGGTV 175 RRA+RE+ AGAREV LI+EP+AAAIGAGLPV+E G+M+VDIGGGTTEVAV+SL G V Sbjct: 123 RRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVV 182 Query: 176 LSESVRVAGDEISDAIGVYLKKVHNLVVGERTAEEIKIRIGSAFPNHEFDQQAMDVRGLH 235 S SVR+ GD +AI Y+++ + ++GE TAE IK IGSA+P E + ++VRG + Sbjct: 183 YSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVRE--IEVRGRN 240 Query: 236 LLSGLPRSINLQAGDLREAIAEPLNVIVEAVKRTLERTPPELAADIVDRGIMLAGGGALV 295 L G+PR L + ++ EA+ EPL IV AV LE+ PPELA+DI +RG++L GGGAL+ Sbjct: 241 LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL 300 Query: 296 RGISDLISHETGIFTHVAEDPLLCVVNGCGQVLEDYKRLRRVLDTPE 342 R + L+ ETGI VAEDPL CV G G+ LE L + E Sbjct: 301 RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 29.3 bits (65), Expect = 0.028 Identities = 24/110 (21%), Positives = 47/110 (42%), Gaps = 12/110 (10%) Query: 76 VERKLLAAVFARTAPDVVNLNPPFAANLASKGGIRDLTPLLPVDAA--DRYLPSVWESGL 133 +E K PD++ A G + ++TP D A D+ P W++ + Sbjct: 69 LEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITP----DKAFQDKLYPFTWDA-V 123 Query: 134 DVEGRQIAIPWYLTVRLSLVNQQLLRQAELDAPPRRWQDVPSYARRMRER 183 G+ IA P + + N+ LL PP+ W+++P+ + ++ + Sbjct: 124 RYNGKLIAYPIAVEALSLIYNKDLLPN-----PPKTWEEIPALDKELKAK 168
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.1 bits (239), Expect = 1e-24 Identities = 45/159 (28%), Positives = 69/159 (43%), Gaps = 10/159 (6%) Query: 24 PKATILVVDDEPAVLRILVMRLQLAGYRVICAEDGEEALEIFHREQPDLLVLDVMLPKMD 83 ATILV DD+ A+ +L L AGY V + DL+V DV++P + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 84 GFAVCRRLRAE-SCVPIIFLSALEAISERVAGLDLGADDYIPKPFSPKELEARIATIL-- 140 F + R++ +P++ +SA + + GA DY+PKPF EL I L Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 141 --RRVGPGSATAEIRDLPVG-----QGVLRVGDLVVDTN 172 RR ++ VG Q + RV ++ T+ Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTD 160
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 36.4 bits (84), Expect = 1e-04 Identities = 19/91 (20%), Positives = 27/91 (29%), Gaps = 3/91 (3%) Query: 101 QQVDAALTQLLTSPDADQEDIQQLAELGLHHEQQHQELLLMDLLDGFSRQPLEPAYQTGA 160 Q V L+ L SP+ ++ E G E Q +L L D +P Sbjct: 101 QNVSELLSLLSNSPNISLSQLKAYLE-GKSEEPSEQFKMLCGLRDALKGRPELAHLSHLV 159 Query: 161 DHHLGPLEPTQARWISCDGGLYEIGHAGAGF 191 + L + Q I G A Sbjct: 160 EQALVSMAEEQGETIV--LGARITPEAYRES 188
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 32.8 bits (74), Expect = 0.005 Identities = 16/42 (38%), Positives = 22/42 (52%) Query: 138 LHAKGLVHGDINPSALLRRQQDGLPVLLDFGLLQPQGTTPWG 179 L G+VH DI P ++ + G PV++D GL G P G Sbjct: 261 LAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKG 302
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.7 bits (74), Expect = 0.002 Identities = 13/42 (30%), Positives = 19/42 (45%), Gaps = 1/42 (2%) Query: 55 KQVLAIAVKAAMGRGDALDHVL-LYGPPGLGKTTMAMVLAEE 95 K +L V M G D+ + L G G+GK+T+ L Sbjct: 578 KYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.9 bits (77), Expect = 0.002 Identities = 30/162 (18%), Positives = 57/162 (35%), Gaps = 9/162 (5%) Query: 229 VERGQTLKLPQGA--VVPKPKAAAKPKPVAIQANPNATSHTVARGQTLNQIAGAYQIPVA 286 VE +T ++P+ V PK + + +P A A N + + Q+ + P Sbjct: 1114 VETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 287 TLIKINGINNPNKLLVGSKLSLRVKPSTTTQPKSTTTVAIKPTAKTTVKPTVKSTTKPAA 346 ++ + V ++ S P++TT +PT + K+ + + Sbjct: 1174 E------TSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSV 1227 Query: 347 KPQP-KPKSTTTVAIKPTAKTTVKPTVKPTVKSTSKPAAKPQ 387 + P + TT + + T T S AK Q Sbjct: 1228 RSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQ 1269 Score = 30.4 bits (68), Expect = 0.019 Identities = 39/185 (21%), Positives = 57/185 (30%), Gaps = 19/185 (10%) Query: 238 PQGAVVPKPKAAAKPKPVAIQA-NPNATSHTVARGQTLNQIAGAYQIPVATLIKINGINN 296 A VP P A + A N S TV + + A VA K N N Sbjct: 1020 VDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKAN 1079 Query: 297 PNKLLVGSKLSLRVKPSTTTQPKSTTTV---------------AIKPTAKTTVKPTVKST 341 V ++ K + TT+ K T TV K T++ + K T Sbjct: 1080 TQTNEV-AQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSET 1138 Query: 342 TKPAAKPQPKPKSTTTVAIKPTAKTTVKPTVKP--TVKSTSKPAAKPQPKPKSTQQVAAK 399 +P A+P + T + + T T +P S + + V Sbjct: 1139 VQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVEN 1198 Query: 400 PSQTQ 404 P T Sbjct: 1199 PENTT 1203
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 30.6 bits (69), Expect = 0.015 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 14/111 (12%) Query: 209 RGTTRDTIDTRLEREGHPWRLIDTAGIRRRRSVNYGPEFFGINRSFKAIERSDVCVLVID 268 RG T T T + E +IDT G +++ E + RS + D +L+I Sbjct: 52 RGITIQTGITSFQWENTKVNIIDTPG-----HMDFLAE---VYRSLSVL---DGAILLIS 100 Query: 269 ALDGVTEQDQRLAGRIEDDGRACVLVVNKWDAVEKDSHTMPMVEKELRAKL 319 A DGV Q + L + G + +NK D D + V ++++ KL Sbjct: 101 AKDGVQAQTRILFHALRKMGIPTIFFINKIDQNGID---LSTVYQDIKEKL 148 Score = 30.2 bits (68), Expect = 0.019 Identities = 33/133 (24%), Positives = 56/133 (42%), Gaps = 26/133 (19%) Query: 6 VAIIGRPNVGKSTLVNRLCRSREAI-----VD------DKPGVTRDR--TYQDG----FW 48 + ++ + GK+TL L + AI VD D + R R T Q G W Sbjct: 6 IGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW 65 Query: 49 GDREFKVVDTGGLVFDDDSEFLPEIREQANLALAEASVALVIVDGQQGVTAADESIAEWL 108 + + ++DT G +FL E+ +L+ A++++ + GV A + L Sbjct: 66 ENTKVNIIDTPG-----HMDFLAEVYR----SLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 109 RTQPCPTLVAVNK 121 R PT+ +NK Sbjct: 117 RKMGIPTIFFINK 129
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 25.4 bits (55), Expect = 0.042 Identities = 12/30 (40%), Positives = 19/30 (63%) Query: 43 NRNSNTLPEGSGYAAGASNPYLSQGSGSGL 72 +R N++ +G AAGA NP++S G G+ Sbjct: 219 DRWGNSMEFINGVAAGALNPFISAGEALGI 248
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 68.8 bits (168), Expect = 9e-14 Identities = 37/144 (25%), Positives = 52/144 (36%), Gaps = 7/144 (4%) Query: 1227 NSTISTGGGDDQIFVNA----IGSHSGAALTNSTIKTGTGDDSVLLSGDLVNSSIHGGDG 1282 N T TG N + + ++ G D+ SG N I+ +G Sbjct: 261 NMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEG 320 Query: 1283 DDQILHSGGGNAEIYGDDGNDTIIGGSGADKISGGKGDDDIFAGDGGDTIDAGDGKDNIT 1342 + GN I + IGGSG D + G D+ + G G D + G G D T Sbjct: 321 SFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGAD--T 378 Query: 1343 ITGGKGISVTTGF-GSDTIVFTAD 1365 + GG G G D+ V D Sbjct: 379 LYGGAGRDTFVYGSGQDSTVAAYD 402 Score = 66.1 bits (161), Expect = 6e-13 Identities = 58/278 (20%), Positives = 97/278 (34%), Gaps = 30/278 (10%) Query: 1101 HSSSGSYNYDYNRSYNYGYDYNN------------NYNGSHQSNYDNNRFNQSSYDYDHS 1148 + +GS Y+YN+S +H Y+ + S D ++ Sbjct: 158 YQGAGSSWYNYNQSNIRNPGSEEYGRQTFTHEIGHALGLAHPGEYNAGEGDPSYNDAVYA 217 Query: 1149 R--IETLGVAIGAEDSTISTGSGNDSVNLQINAGSSAIGLKNSVLETGEGQDQVNISVNA 1206 + ++ E+ T + +G+ I+ ++ L + + T G + N Sbjct: 218 EDSYQFSIMSYWGENETGADYNGHYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNT 277 Query: 1207 LGHSFYHGKSTEKGDAKTLLNSTISTGGGDDQIFVNAIGSHSGAALTNSTIKTGTGDDSV 1266 FY + +K L+ S GG D F N I G S Sbjct: 278 -DRDFYTATDS----SKALIFSVWDAGGTDTFDFSGYSN--------NQRINLNEGSFS- 323 Query: 1267 LLSGDLVNSSIHGGDGDDQILHSGGGNAEIYGDDGNDTIIGGSGADKISGGKGDDDIFAG 1326 + G N SI G + + G GN + G+ ++ + GG+G D + GG G D ++ G Sbjct: 324 DVGGLKGNVSIAHGVTIENAI-GGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGG 382 Query: 1327 DGGDTIDAGDGKDNITITGGKGISVTTGF-GSDTIVFT 1363 G DT G G+D+ G D F Sbjct: 383 AGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSAFR 420 Score = 37.6 bits (87), Expect = 4e-04 Identities = 23/125 (18%), Positives = 46/125 (36%), Gaps = 8/125 (6%) Query: 1227 NSTISTGGGDDQIFVNAIGSHSGAALTNSTIKTGTGDDSVLLSGDLVNSSIHGGDGDDQI 1286 N +I+ G + + ++ ++ G G+D +L G +++GG G D Sbjct: 331 NVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGND--VLYGGAGADTLYGGAGRDTF 388 Query: 1287 LHSGGGNAEIYGDDGNDTIIGGSGADKIS------GGKGDDDIFAGDGGDTIDAGDGKDN 1340 ++ G ++ + D G +S D F G G + + D ++ Sbjct: 389 VYGSGQDSTVAAYDWIADFQKGIDKIDLSAFRNEGQLSFVQDQFTGKGQEVMLQWDAANS 448 Query: 1341 ITITG 1345 IT Sbjct: 449 ITNLW 453 Score = 36.1 bits (83), Expect = 0.001 Identities = 16/113 (14%), Positives = 30/113 (26%), Gaps = 5/113 (4%) Query: 1276 SIHGGDGDDQILHSGGGNAEIYGDDGNDTIIGGSGADKISGGKGDDDIFAGDGGDTIDAG 1335 +I G + +G + D + + ++ G DT D Sbjct: 253 AIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIF-----SVWDAGGTDTFDFS 307 Query: 1336 DGKDNITITGGKGISVTTGFGSDTIVFTADYYRSLLEGASSGTNIFADDINNI 1388 +N I +G G + G S + + +NI Sbjct: 308 GYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADNI 360
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 115 bits (289), Expect = 4e-29 Identities = 55/148 (37%), Positives = 84/148 (56%), Gaps = 8/148 (5%) Query: 8 RLRNFCIIAHIDHGKSTLADRLLQDTGTVA--GR-DMQEQFLDNMDLERERGITIKLQAA 64 ++ N ++AH+D GK+TL + LL ++G + G D DN LER+RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 65 RMNYTAADGESYVLNLIDTPGHVDFSYEVSRSLQACEGALLVVDASQGVEAQTLANVYLA 124 + E+ +N+IDTPGH+DF EV RSL +GA+L++ A GV+AQT + Sbjct: 62 SFQW-----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 125 LENDLEIIPVLNKIDLPGSDPERIKEEI 152 + + I +NKID G D + ++I Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDI 144 Score = 98.8 bits (246), Expect = 9e-24 Identities = 46/213 (21%), Positives = 97/213 (45%), Gaps = 12/213 (5%) Query: 167 SAKTGLGVPEIMQAVVDRIPPPADTIDKPTKALIFDSYYDSYRGVIVYFRVISGRISTKD 226 SAK +G+ +++ + ++ +F Y R + Y R+ SG + +D Sbjct: 220 SAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRD 279 Query: 227 KVLLMASKKSYELDEIGVMSPDQ-CEVNELHAGEVGYLAASIKAVADARVGDTITLLNAP 285 V + + K+ ++ E+ + C++++ ++GE+ L + +GDT L P Sbjct: 280 SVRI-SEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLL---P 334 Query: 286 ADEPLPGYTEAKPMVFCGLFPTDSDQYPDLREALDKLQLSDAALKYEPETSSAMGFGFRC 345 E + P++ + P+ Q L +AL ++ SD L+Y ++++ Sbjct: 335 QRERIEN---PLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEII---L 388 Query: 346 GFLGLLHMEIVQERLEREYDLDLIVTAPSVIYK 378 FLG + ME+ L+ +Y +++ + P+VIY Sbjct: 389 SFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYM 421 Score = 35.2 bits (81), Expect = 8e-04 Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 2/79 (2%) Query: 404 IEEPYVRMEIYAPNEYNGTLMGLCQERRGEYIDMKYITTERVTLIYELPLAEVVTDFFDQ 463 + EPY+ +IYAP EY + +D + E V L E+P + ++ Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNE-VILSGEIPARC-IQEYRSD 592 Query: 464 MKSRTKGYASMEYHLIGYR 482 + T G + L GY Sbjct: 593 LTFFTNGRSVCLTELKGYH 611
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.4 bits (71), Expect = 0.001 Identities = 10/34 (29%), Positives = 21/34 (61%) Query: 17 KTGFSLLEVLVTITIVSIISAYAIPTYRRNLSQG 50 + GF+LLE++V I I+ ++++ +P N + Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKA 40
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 53.7 bits (129), Expect = 8e-12 Identities = 20/60 (33%), Positives = 40/60 (66%) Query: 15 GFTLIEVLLTVVIIGILSAVAMPNYFNQVQRAKQSEAVATLAQIQNTLAAYIDEFNLAPT 74 GFTL+E+++ +VIIG+L+++ +PN ++A + +AV+ + ++N L Y + + PT Sbjct: 9 GFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHYPT 68
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 51.4 bits (123), Expect = 5e-11 Identities = 22/63 (34%), Positives = 37/63 (58%) Query: 34 QQGFTLVELMIVIVIVGILSAVALPQFTGIKEKAELNTQLGEGAGLAKECAAAIITDGPY 93 Q+GFTL+E+M+VIVI+G+L+++ +P G KEKA+ + + L + + Y Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHY 66 Query: 94 PDN 96 P Sbjct: 67 PTT 69
>PF06580#Sensor histidine kinase Length = 349 Score = 31.0 bits (70), Expect = 0.010 Identities = 16/81 (19%), Positives = 30/81 (37%), Gaps = 20/81 (24%) Query: 399 LIENAFKY----SPEEKRVELSCVSTHEHVRLQVRDHGPGVPEADQELIFQQFQRGSNTA 454 L+EN K+ P+ ++ L + V L+V + G + +E Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------- 309 Query: 455 QQPGSGVGLALVYSLVKRMGG 475 +G GL V ++ + G Sbjct: 310 ---STGTGLQNVRERLQMLYG 327
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 43.4 bits (102), Expect = 6e-07 Identities = 23/96 (23%), Positives = 38/96 (39%) Query: 24 PDQLKAIAFKHHQQGNINEAQKAYQEFINSGLSDPDVFSNFALICQSQGEIDKAINIYKR 83 +QL ++AF +Q G +A K +Q D F Q+ G+ D AI+ Y Sbjct: 36 LEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSY 95 Query: 84 SIKLFPRHAFSHANLGYLFFQIGMLDDAEAAIRQAI 119 + + + Q G L +AE+ + A Sbjct: 96 GAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQ 131 Score = 38.8 bits (90), Expect = 3e-05 Identities = 23/124 (18%), Positives = 41/124 (33%), Gaps = 10/124 (8%) Query: 42 EAQKAYQEFINSGLS----------DPDVFSNFALICQSQGEIDKAINIYKRSIKLFPRH 91 E Q A + F+ G + + + A G+ + A +++ L Sbjct: 10 EYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYD 69 Query: 92 AFSHANLGYLFFQIGMLDDAEAAIRQAIVIQPNLANAYSYLGLVLREKGRLTDAEDITRK 151 + LG +G D A + ++ + L +KG L +AE Sbjct: 70 SRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFL 129 Query: 152 AIEL 155 A EL Sbjct: 130 AQEL 133 Score = 36.4 bits (84), Expect = 2e-04 Identities = 19/93 (20%), Positives = 34/93 (36%) Query: 97 NLGYLFFQIGMLDDAEAAIRQAIVIQPNLANAYSYLGLVLREKGRLTDAEDITRKAIELQ 156 +L + +Q G +DA + V+ + + LG + G+ A + Sbjct: 41 SLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMD 100 Query: 157 PDLVDAYVNLGQILQNQGKLDEAEHTTRQAIEL 189 + + L +G+L EAE A EL Sbjct: 101 IKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Score = 31.4 bits (71), Expect = 0.008 Identities = 18/94 (19%), Positives = 32/94 (34%) Query: 154 ELQPDLVDAYVNLGQILQNQGKLDEAEHTTRQAIELQDDSASIYLNLGGILQDQGDLTDA 213 E+ D ++ +L GK ++A + L + +L LG Q G A Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLA 89 Query: 214 EANTRKAMHLQADLPDVNLNLSIILKDLGRIEEA 247 + + P + + L G + EA Sbjct: 90 IHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEA 123
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 31.3 bits (70), Expect = 0.011 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 16/69 (23%) Query: 313 ISANYVAKEGDNGDPSDGGVGNGNSKGKFLAKVDYGN----------------PQWQVSA 356 I +Y+A+ GDN D + G S ++L+KV YGN QW + Sbjct: 204 IYYSYLAENGDNVDLNGNEAGRDRSAMRYLSKVQYGNATPAADLYLWTSATPAVQWLFTL 263 Query: 357 AYAYTQQGM 365 + Y ++G+ Sbjct: 264 VFDYGERGV 272
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 28.2 bits (62), Expect = 0.050 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 7/100 (7%) Query: 8 TYSGLAAVLALGTG-FSQNGVANARE----VRVYSGRHYNTDRQIYKKFSEQTGIKVRLI 62 T + + A+ AL T FS + +A E + + + YN ++ KKF + TGIKV + Sbjct: 5 TGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVE 64 Query: 63 ESSGISLLERLKREGANSQADVIILVDAARISNAAKEGLL 102 L E+ + A II R A+ GLL Sbjct: 65 HPD--KLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLL 102
>PF04183#IucA / IucC family Length = 580 Score = 32.2 bits (73), Expect = 0.001 Identities = 15/50 (30%), Positives = 22/50 (44%), Gaps = 1/50 (2%) Query: 44 KEGCCVVFQETISTTVKEKERPQLMAALSALD-EGDELVVSKMDRLGRTQ 92 +E V+++E +K E P LMA L D L + +DR G Sbjct: 344 QEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDA 393
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 38.0 bits (88), Expect = 4e-05 Identities = 24/125 (19%), Positives = 44/125 (35%), Gaps = 2/125 (1%) Query: 321 KRYQTFIKRLLGD--LLRQNTDINPKDSLNYTYRAASKCSEGDYQGAIEDYTKALELDSK 378 + YQ ++ L + +I+ A ++ G Y+ A + + LD Sbjct: 9 QEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHY 68 Query: 379 NSLAYMFRGACHDLSGDSKAALDDYSESIELNPSNADIYYTRGVTLRDSGDDIGALSDFT 438 +S ++ GAC G A+ YS ++ + L G+ A S Sbjct: 69 DSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLF 128 Query: 439 LTIKL 443 L +L Sbjct: 129 LAQEL 133
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 41.1 bits (96), Expect = 6e-06 Identities = 17/104 (16%), Positives = 37/104 (35%), Gaps = 3/104 (2%) Query: 589 GAIADYNKSLDINPQLADAYNNRGLAKYDSKDYQGAIADYNKSLDINPHFALAYNNRGLA 648 G IA N+ I+ + + +Y S Y+ A + ++ + + + G Sbjct: 23 GTIAMLNE---ISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGAC 79 Query: 649 KDELGNHQGAIADYNKAIEIKPQYANAYFNRGNAKSDLGDTQGA 692 + +G + AI Y+ + + F+ G+ A Sbjct: 80 RQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEA 123 Score = 39.5 bits (92), Expect = 2e-05 Identities = 17/95 (17%), Positives = 34/95 (35%) Query: 744 YNNRGLAKYDSKDYQGAIADYTKAIEIDPKDADAYSNRGYAKSHLGDTQGAIADYTKAIE 803 + +Y S Y+ A + +D D+ + G + +G AI Y+ Sbjct: 39 LYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAI 98 Query: 804 IDPKDAPTYYNRGYAKSHLGDTQGAITDYTKAIEI 838 +D K+ ++ G+ A + A E+ Sbjct: 99 MDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Score = 39.1 bits (91), Expect = 3e-05 Identities = 14/84 (16%), Positives = 31/84 (36%) Query: 892 GDHQGAIADYTKAIEINPQYSNAYYNRGNAKSELKDYQEAIADYTKAIEIDPKDAPAYYN 951 G ++ A + ++ S + G + + Y AI Y+ +D K+ ++ Sbjct: 50 GKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFH 109 Query: 952 RGNAKSELKDYQEAIADYSKAIEI 975 + + EA + A E+ Sbjct: 110 AAECLLQKGELAEAESGLFLAQEL 133 Score = 38.8 bits (90), Expect = 4e-05 Identities = 16/92 (17%), Positives = 31/92 (33%), Gaps = 3/92 (3%) Query: 793 GAIADYTKAIEIDPKDAPTYYNRGYAKSHLGDTQGAITDYTKAIEIDPKDSDAYSNRGYA 852 G IA + + Y+ + + G + A + +D DS + G Sbjct: 23 GTIAMLNEISSDTLEQ---LYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGAC 79 Query: 853 KSHLGDTQGAIADYTKAIEIDPKDADAYSNRG 884 + +G AI Y+ +D K+ + Sbjct: 80 RQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAA 111 Score = 38.4 bits (89), Expect = 4e-05 Identities = 14/103 (13%), Positives = 34/103 (33%) Query: 268 INPSNADAYLNRGHTKLNQRDFDGAIADFNHALNIDPQVDNIYLKRGVAKDELGNHQGAI 327 I+ + + + ++ A F +D +L G + +G + AI Sbjct: 31 ISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAI 90 Query: 328 ADYTKAIEIDPQDALAYNNRGVAKSKSNDFQGSISDCTKAIEI 370 Y+ +D ++ + + + + S A E+ Sbjct: 91 HSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Score = 38.0 bits (88), Expect = 7e-05 Identities = 22/127 (17%), Positives = 45/127 (35%), Gaps = 7/127 (5%) Query: 753 DSKDYQGAIADYTKA-------IEIDPKDADAYSNRGYAKSHLGDTQGAIADYTKAIEID 805 D+++YQ A+ + K EI + + + + G + A + +D Sbjct: 7 DTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLD 66 Query: 806 PKDAPTYYNRGYAKSHLGDTQGAITDYTKAIEIDPKDSDAYSNRGYAKSHLGDTQGAIAD 865 D+ + G + +G AI Y+ +D K+ + G+ A + Sbjct: 67 HYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESG 126 Query: 866 YTKAIEI 872 A E+ Sbjct: 127 LFLAQEL 133 Score = 37.6 bits (87), Expect = 9e-05 Identities = 12/82 (14%), Positives = 28/82 (34%) Query: 531 EIDPKDADAFTNRGLAKYDSKDYQGAIADYNKAIEIDPQLADAYNNRGLVKDELGDHQGA 590 EI + + +Y S Y+ A + +D + + G + +G + A Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLA 89 Query: 591 IADYNKSLDINPQLADAYNNRG 612 I Y+ ++ + + Sbjct: 90 IHSYSYGAIMDIKEPRFPFHAA 111 Score = 36.8 bits (85), Expect = 2e-04 Identities = 18/116 (15%), Positives = 34/116 (29%), Gaps = 19/116 (16%) Query: 175 GAIADYSKVIEIDPDQLYKYRDECSAYFHRGKAKHSSGNISGAIADYSKAIEIDPKNDSA 234 G IA +++ +QLY ++ SG A + +D + Sbjct: 23 GTIAMLNEISSDTLEQLYSL----------AFNQYQSGKYEDAHKVFQALCVLDHYDSRF 72 Query: 235 YNNRGIIEDDLGQRKLDDFYYQLAIADYDKAIDINPSNADAYLNRG--HTKLNQRD 288 + G +GQ Y LAI Y ++ + + + Sbjct: 73 FLGLGACRQAMGQ-------YDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELA 121 Score = 35.3 bits (81), Expect = 5e-04 Identities = 13/82 (15%), Positives = 29/82 (35%) Query: 906 EINPQYSNAYYNRGNAKSELKDYQEAIADYTKAIEIDPKDAPAYYNRGNAKSELKDYQEA 965 EI+ Y+ + + Y++A + +D D+ + G + + Y A Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLA 89 Query: 966 IADYSKAIEINPQLALAYNNRG 987 I YS ++ + + Sbjct: 90 IHSYSYGAIMDIKEPRFPFHAA 111 Score = 34.9 bits (80), Expect = 6e-04 Identities = 20/128 (15%), Positives = 42/128 (32%), Gaps = 7/128 (5%) Query: 923 SELKDYQEAIADYTKA-------IEIDPKDAPAYYNRGNAKSELKDYQEAIADYSKAIEI 975 ++ ++YQ A+ + K EI Y+ + + Y++A + + Sbjct: 6 TDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVL 65 Query: 976 NPQLALAYNNRGLAKYDSKDYQGTIADYNKAIEIDPQYANAYKNRGNAKKELGVLKGACE 1035 + + + G + Y I Y+ +D + + + G L A Sbjct: 66 DHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAES 125 Query: 1036 DWKKAAEL 1043 A EL Sbjct: 126 GLFLAQEL 133 Score = 34.9 bits (80), Expect = 7e-04 Identities = 9/87 (10%), Positives = 30/87 (34%) Query: 56 DEYLESGKSKLEKKDFYGAIEDLNKEIEINSQDVAAYSKRANLKEKLGDHKGAIDDFTKA 115 ++ ++ + + A + ++ D + ++ +G + AI ++ Sbjct: 37 EQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYG 96 Query: 116 IEIDPNHAHPYYNRGFSKWQLGDIQGA 142 +D ++ Q G++ A Sbjct: 97 AIMDIKEPRFPFHAAECLLQKGELAEA 123 Score = 31.4 bits (71), Expect = 0.010 Identities = 16/104 (15%), Positives = 34/104 (32%) Query: 701 EINPQYAAAYYNRGNAKRKLGDNQGAIADCSKAIEINPHFALAYNNRGLAKYDSKDYQGA 760 EI+ Y+ + + G + A ++ + + + G + Y A Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLA 89 Query: 761 IADYTKAIEIDPKDADAYSNRGYAKSHLGDTQGAIADYTKAIEI 804 I Y+ +D K+ + G+ A + A E+ Sbjct: 90 IHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Score = 30.3 bits (68), Expect = 0.025 Identities = 16/117 (13%), Positives = 41/117 (35%), Gaps = 7/117 (5%) Query: 617 DSKDYQGAIADYNKS-------LDINPHFALAYNNRGLAKDELGNHQGAIADYNKAIEIK 669 D+++YQ A+ + K +I+ + + + G ++ A + + Sbjct: 7 DTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLD 66 Query: 670 PQYANAYFNRGNAKSDLGDTQGAIAVYSKSIEINPQYAAAYYNRGNAKRKLGDNQGA 726 + + G + +G AI YS ++ + ++ + G+ A Sbjct: 67 HYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEA 123
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 37.2 bits (86), Expect = 6e-05 Identities = 15/137 (10%), Positives = 43/137 (31%), Gaps = 4/137 (2%) Query: 397 LELSPNDAVIYNNRGNAKRKLEDYQSAIEDYNKSIEINPSSAAPYFNRGDIKYVLDDHKG 456 E+S + + + + Y+ A + + ++ + + G + + + Sbjct: 29 NEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDL 88 Query: 457 AIDDYNLALEVDPDDPFLYAKRGDLRVALHDYQGAIADYTKAIEINPQLAIAYYNRGEAK 516 AI Y+ +D +P + + + A + + +L E Sbjct: 89 AIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEA----ESGLFLAQELIADKTEFKELS 144 Query: 517 KEIGDLKGACEDWKKAA 533 + + A + K+ Sbjct: 145 TRVSSMLEAIKLKKEME 161
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.8 bits (69), Expect = 0.047 Identities = 28/127 (22%), Positives = 47/127 (37%), Gaps = 2/127 (1%) Query: 610 DSLLESISTLNRYINDLLGEQSNLGELKATL-NGIERYRRSIPNAPRVKASLLKLKELGL 668 + I TL L Q+ L + N I KA+L K Sbjct: 242 TADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLE 301 Query: 669 SEIGLIDKVIKDFVSGEASEVVYKKIISAWAQKVEEVIRINAPSLASSTRDYLDRTIGTF 728 + +++ + + KK + A QK+EE +I+ S S RD LD + Sbjct: 302 HQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRD-LDASREAK 360 Query: 729 RETDSEH 735 ++ ++EH Sbjct: 361 KQLEAEH 367
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 72.7 bits (178), Expect = 6e-18 Identities = 41/107 (38%), Positives = 57/107 (53%), Gaps = 3/107 (2%) Query: 105 SGLSITDLKIGDGPEATAGQTVSVNYRGTLENGQEFDSSYKRG-PFEFPLGAGRVIKGWD 163 SGL + G G + TV+V Y GTL +G FDS+ K G P F + +VI GW Sbjct: 126 SGLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVS--QVIPGWT 183 Query: 164 EGVAGMKVGGKRKLVIPPELGYGSRGAGRVIPGNATLIFEVELLGIK 210 E + M G ++ +P +L YG R G I N TLIF++ L+ +K Sbjct: 184 EALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVK 230
>PF07132#Harpin protein (HrpN) Length = 356 Score = 29.3 bits (65), Expect = 0.038 Identities = 24/79 (30%), Positives = 34/79 (43%) Query: 403 GGSGHSPADVDKVLADFQKMRGFMQQMSKGGGMPGMPGMPGMPGMGGGLPGMGGPGGGMS 462 G +++ + L+D FM M GG G+ G+ G GG GG GGG+ Sbjct: 38 SAFGGQRSNIAEQLSDIMTTMMFMGSMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLG 97 Query: 463 GMGGAGMPEPASGGRGGGS 481 G+G+ GG GG Sbjct: 98 SSLGSGLGSALGGGLGGAL 116
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 62.7 bits (152), Expect = 8e-14 Identities = 36/99 (36%), Positives = 47/99 (47%), Gaps = 1/99 (1%) Query: 70 SDADDSLAGASADEVIFGGRGDDVLLGGAGDDQVAGGNGDDWLYGGFGDDTLKGDRGADT 129 S D GA D++I G G+D L G G+D ++GGNGDD LYGG G+D L G G + Sbjct: 734 SKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNY 793 Query: 130 YWLSRGVDVIIVF-SFAENDRISVGDGVLCSLRQAGDDL 167 G D V + + + G G G DL Sbjct: 794 LNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADL 832 Score = 53.8 bits (129), Expect = 7e-11 Identities = 48/145 (33%), Positives = 67/145 (46%), Gaps = 16/145 (11%) Query: 41 GGDGNDIELYTKSFSGVLPESLRDPRMIVSDADDSLAGASADEVIFGGRGDD-------- 92 G DGND LY + L D ++ D +D L G + + + GG GDD Sbjct: 751 GNDGNDR-LYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQGNS 809 Query: 93 ----VLLGGAGDDQVAGGNGDDWLYGGFGDDTLKGDRGADTYWLSRGV-DVIIVFSFAEN 147 VL GG G+D++ G G D L GG GDD LKG G D Y G II + Sbjct: 810 LAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKE 869 Query: 148 DRISVGDGVL--CSLRQAGDDLSIR 170 D++S+ D + ++ G+DL + Sbjct: 870 DKLSLADIDFRDVAFKREGNDLIMY 894 Score = 49.2 bits (117), Expect = 3e-09 Identities = 23/63 (36%), Positives = 34/63 (53%) Query: 67 MIVSDADDSLAGASADEVIFGGRGDDVLLGGAGDDQVAGGNGDDWLYGGFGDDTLKGDRG 126 +I + D G+ ++ G GDD++ G G+D++ G G+D L GG GDD L G G Sbjct: 722 LIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDG 781 Query: 127 ADT 129 D Sbjct: 782 NDK 784 Score = 41.1 bits (96), Expect = 1e-06 Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 2/84 (2%) Query: 83 EVIFGGRGDDVLLGGAGDDQVAGGNGDDWLYGGFGDDTLKGDRGADTYWLSRGVDVIIVF 142 E + G D G D G +GDD + G G+D L GD+G DT G D + + Sbjct: 720 EELIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQL--Y 777 Query: 143 SFAENDRISVGDGVLCSLRQAGDD 166 ND++ G GDD Sbjct: 778 GGDGNDKLIGVAGNNYLNGGDGDD 801
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.1 bits (73), Expect = 0.006 Identities = 39/181 (21%), Positives = 63/181 (34%), Gaps = 54/181 (29%) Query: 200 ARIPKGVLLVGPPGTGKTLLSKAV---AGEAEVPFFII---SGSEFV---ELF---VGA- 246 + +++ G GTGK L+++A+ PF I + + ELF GA Sbjct: 157 MQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAF 216 Query: 247 -GAARVRD-LFEQAKKKAPCIIFIDELDAIGKS---------RSGSMGVVGGNDEREQTL 295 GA FEQA+ +F+DE+ + + G VGG Sbjct: 217 TGAQTRSTGRFEQAEGGT---LFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRS-- 271 Query: 296 NQLLTEMDGFSSTDKPVIVLAATNQPEVLDAALLRPGRFDRQVLVDRPDLSGRKTILEIY 355 V ++AATN+ + G F R DL R ++ + Sbjct: 272 ---------------DVRIVAATNKDL---KQSINQGLF-------REDLYYRLNVVPLR 306 Query: 356 V 356 + Sbjct: 307 L 307
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.8 bits (72), Expect = 7e-04 Identities = 15/70 (21%), Positives = 27/70 (38%) Query: 84 RLASSLSLGTYFYLGDLVTNPTYQGQGLAVQMLRYLEAIARDAGCRQIHLDAGVERFGAH 143 R+ + Y + D+ Y+ +G+ +L A++ + L+ A Sbjct: 79 RIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISAC 138 Query: 144 RFYAKQGFNI 153 FYAK F I Sbjct: 139 HFYAKHHFII 148
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 80.1 bits (197), Expect = 1e-19 Identities = 50/205 (24%), Positives = 88/205 (42%), Gaps = 18/205 (8%) Query: 12 KGRVALVTGANSGLGLETAKALLNKGARVIMACRSLPTGEDVRQVILERNDSTKLDLIEL 71 +G++A +TGA G+G A+ L ++GA + + E V + ++ + Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSS--LKAEARHAEAFPA 64 Query: 72 DLADLASVRRAAEQVESQYSRVDLLINNAGV--MATPKTLSKQGLELQFAVNHLGHMALT 129 D+ D A++ ++E + +D+L+N AGV +LS + E F+VN G + Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 130 LKLLPLLAKQHGARVVTVTSGAQYMGRIAWDDLQGIKQYDRWAAYSQSKLANVMFALELD 189 + + + +VTV S + R + AAY+ SK A VMF L Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTS------------MAAYASSKAAAVMFTKCLG 172 Query: 190 KRMRQTASGIASLLAHPGLARTNLQ 214 + I + PG T++Q Sbjct: 173 --LELAEYNIRCNIVSPGSTETDMQ 195
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 31.1 bits (70), Expect = 0.004 Identities = 15/114 (13%), Positives = 34/114 (29%), Gaps = 4/114 (3%) Query: 119 ELDQQHATAYYNRGFAKFNQSDNKGAINDYNKALALNPKHAKSYYNRAIIKNNINDIKGA 178 E+ Y+ F ++ + A + L+ ++ + + + A Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLA 89 Query: 179 ISDYTKAIEAMPLFAFAYYNRGNLMERLGRRQAAVTDHEKALEINPQLITAMNE 232 I Y+ ++ + + G A E L + +LI E Sbjct: 90 IHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEA----ESGLFLAQELIADKTE 139 Score = 30.3 bits (68), Expect = 0.009 Identities = 9/48 (18%), Positives = 17/48 (35%) Query: 39 YQGAIDSYSKAIDINPNNAIAYNNRGNAKDELGDYQSALNDYNKAIDI 86 Y AI SYS ++ + + G+ A + A ++ Sbjct: 86 YDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 27.8 bits (62), Expect = 0.025 Identities = 20/78 (25%), Positives = 29/78 (37%), Gaps = 5/78 (6%) Query: 40 GIARVYCPCEETEGMTLAFLQEGDQLRTDRLCSEGVCVEALTPLCFRSDAEIRDGHDFDA 99 GI R++ T+G L L+E LR + +E D EI D H Sbjct: 42 GIERIWSAIGATDGFALLNLEEAITLRERGWKGPILMLEGFFHA---QDLEIYDQHRLTT 98 Query: 100 V--NEWTLQLLRIRHLGN 115 + W L+ L+ L Sbjct: 99 CVHSNWQLKALQNARLKA 116
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 68.2 bits (166), Expect = 7e-16 Identities = 45/190 (23%), Positives = 76/190 (40%), Gaps = 5/190 (2%) Query: 3 RTILISGASRGIGRAIAERMLADG-HRLSLGLRDPKCLIGSSLDPAIAGSEQVFLHPYEA 61 + I+GA++GIG A+A + + G H ++ K S A A + F P + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF--PADV 66 Query: 62 QDVNAAESWVSASLAHFSGFDSLIHCAGIFHRTPIRFNDNQQHEIDQLWQVNVMGPWMLS 121 +D A + + D L++ AG+ I + E + + VN G + S Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLI--HSLSDEEWEATFSVNSTGVFNAS 124 Query: 122 RAAWSQLECHAEARIIVLVSMSGKRSKGRLAGYTVSKFALMGLCQTMRNEGWEQGIRVTA 181 R+ + I+ + S + +A Y SK A + + + E E IR Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 182 ICPGWVNTDM 191 + PG TDM Sbjct: 185 VSPGSTETDM 194
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 79.9 bits (197), Expect = 1e-18 Identities = 36/169 (21%), Positives = 79/169 (46%), Gaps = 11/169 (6%) Query: 302 VEILEVRTIGPTLGAENIRRSLIAALSGLALVAVFMVVAYRLA---GLVAVLALSLYALF 358 ++I ++GP + E + ++ + L A V + + R L AV+AL L Sbjct: 135 LKITSFESVGPKVSGELVWTAVWSLL--AATVVIMFYIWVRFEWQFALGAVVALVHDVLL 192 Query: 359 NLAMYALIPVILTLPGIAGFILSIGMAVDANVLIFERVKDELR--RGNTLIRSIETGFSQ 416 + ++A++ + L +A + G +++ V++F+R+++ L + L + ++ Sbjct: 193 TVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNE 252 Query: 417 ALSSIVDGHLTTLISCAALFFLGTGLVKGFAATLGIGVVL----SLFTA 461 LS V +TTL++ + G +++GF + GV S++ A Sbjct: 253 TLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVA 301 Score = 32.1 bits (73), Expect = 0.005 Identities = 13/83 (15%), Positives = 30/83 (36%), Gaps = 12/83 (14%) Query: 1 MARQQGWFALILALAIAAGSVTASFPLELGLDLRGGSQLTLEVQPAGEITRVKSEQLEAV 60 Q F + + IA+ + L G+D +GG+ + E A ++ ++ Sbjct: 17 FRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRA------ 70 Query: 61 KAVLDRRVNGLGVAESTLQTIGD 83 + L + + + + D Sbjct: 71 ------ALEPLELGDVIISEVRD 87
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.020 Identities = 11/32 (34%), Positives = 16/32 (50%) Query: 30 CLALLGPSGCGKSTTLRLIAGLDQPNEGSITI 61 + L G G GKST + + GLD ++ I Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDI 629
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 63.2 bits (153), Expect = 5e-13 Identities = 75/317 (23%), Positives = 140/317 (44%), Gaps = 21/317 (6%) Query: 102 YAAAGWLIPLDPWIDQQKIDSIAPGAMLGNNFDGKLYRWPLVADMGLLYWRTDLMNKPPR 161 YA +G L + P D+ D + P ++GKL +P+ + L + DL+ PP+ Sbjct: 96 YAQSGLLAEITP--DKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPK 153 Query: 162 TPEELIKVSLKLQKEGRVANGYVWQGRQYEGLSCVFLEVLDGFGGQWLEPETD--NVGLD 219 T EE+ + +L+ +G+ A + Q + + + G+ ++ + D +VG+D Sbjct: 154 TWEEIPALDKELKAKGKSALMFNLQEPYF---TWPLIAADGGYAFKYENGKYDIKDVGVD 210 Query: 220 SSASLKAASWLRELILSGASPKAVINYAENEALQAFKSGDVALMRNWPYAWGELQKPNSD 279 ++ + ++L +LI A +Y+ EA AF G+ A+ N P+AW + Sbjct: 211 NAGAKAGLTFLVDLI-KNKHMNADTDYSIAEA--AFNKGETAMTINGPWAWSNIDTS--- 264 Query: 280 VRGNVGVTTMVASAGNRSTSTLGSWGFSILKGSSNPQAAAEAIAFLTSTSAQKTLFLNES 339 + N GVT + G S +G I S N + A E + T + +N+ Sbjct: 265 -KVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTD-EGLEAVNKD 322 Query: 340 YTPTKVELFKDQELLSKSQILPELAKALESTDERPSTPLYAQISDVLQRNLSSIL---TG 396 V L +E L+K P +A +E+ + P Q+S ++++ +G Sbjct: 323 KPLGAVALKSYEEELAKD---PRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASG 379 Query: 397 QSSVSDAMANAQANTEK 413 + +V +A+ +AQ K Sbjct: 380 RQTVDEALKDAQTRITK 396
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 136 bits (345), Expect = 2e-37 Identities = 81/378 (21%), Positives = 144/378 (38%), Gaps = 71/378 (18%) Query: 5 VGIDLGTTNSVVAVLEAG----RPQVIANAEGSRTTPSVVGYSKEAELLVGQLARRQLVL 60 + IDLGT N+++ V G P V+A + +P V VG A++ L Sbjct: 13 LSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSV-------AAVGHDAKQMLGR 65 Query: 61 NPRNTFANLKRFVGRGWDEMDDSSLSVPYTVRANEQGNVRVSCQVTEREYAPEELVASII 120 P N A +R + G V + E+++ I Sbjct: 66 TPGNIAA-----------------------IRPMKDG-------VIADFFVTEKMLQHFI 95 Query: 121 RKLVDDAATYLGEPVEAAVVTVPAYFNDAQRQATRDAGRLAGITVERILNEPTAAALAYG 180 +++ ++ P +V VP +R+A R++ + AG ++ EP AAA+ G Sbjct: 96 KQVHSNS---FMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAG 152 Query: 181 FDRSAARRVLVFDLGGGTFDVSLMRVANGVFDVKATCGDTQLGGNDFDQRIVDWLAEAFK 240 S A +V D+GGGT +V+++ + V ++GG+ FD+ I++++ + Sbjct: 153 LPVSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYG 207 Query: 241 TKHGLDLRRDRQALQRLIEAAEKAKQELSGVL----STPISLPFIATGPDGPLHIETSLD 296 + G AE+ K E+ I + P + Sbjct: 208 SLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLN-S 253 Query: 297 RPTFEGLCPDLLDRLLNPVQTALRDSG--WSADDVDD-VVLVGGGTRMPMVQQLLRTLVA 353 E L + L +++ V AL ++D + +VL GGG + + +LL Sbjct: 254 NEILEAL-QEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETG 312 Query: 354 SEPCQSVNPDEVVAVGGA 371 + +P VA GG Sbjct: 313 IPVVVAEDPLTCVARGGG 330
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.8 bits (80), Expect = 4e-04 Identities = 30/192 (15%), Positives = 66/192 (34%), Gaps = 7/192 (3%) Query: 42 LDAVRETLPGQVNQADQLLQKRDDFITTARKQAEEIVHQANQQREQLVNA-ASIRQEAEK 100 L A+ Q+ L + + R Q + N+ E + + +E+ Sbjct: 127 LTALGAEADTLKTQSSLLQAR----LEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEE 182 Query: 101 QVAELRDQSRQQCEQLLQATRQQSVQLEHEMQSKLVQLEQQFSSRRQ-QLEQEALERRQQ 159 +V L ++Q Q+ + L+ + +L L + ++E+ L+ Sbjct: 183 EVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS 242 Query: 160 LDREAIDIKRQLTEQHERNRQQAIQELDQIRSEGSRLQKEAQNEAERLHNDALQFRQQTH 219 L + K + EQ E +A+ EL +S+ +++ E + E F+ + Sbjct: 243 LLHKQAIAKHAVLEQ-ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL 301 Query: 220 QQCESLIQRSRQ 231 + Sbjct: 302 DKLRQTTDNIGL 313
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 205 bits (524), Expect = 3e-71 Identities = 94/157 (59%), Positives = 115/157 (73%) Query: 1 MRALYPGSFDPLTLGHLDLIERGCALFGEVVVAVLSNPAKTSTFTLQQRFNQIHVATAHC 60 M A+YPGSFDP+T GHLD+IERGC LF +V VAVL NP K F++Q+R QI A AH Sbjct: 1 MNAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHL 60 Query: 61 KGVSVICFEGLTVSCARHNQVDLILRGLRAMSDFEYELQIAHTNRSLAPDFETIFLATAA 120 V FEGLTV+ AR Q ILRGLR +SDFE ELQ+A+TN++LA D ET+FL T+ Sbjct: 61 PNAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTST 120 Query: 121 HHSFLSSSMVKEVARFGGNIDHMVPEVVAQDLHRLFN 157 +SFLSSS+VKEVARFGGN++H VP VA L+ F+ Sbjct: 121 EYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFH 157
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 229 bits (586), Expect = 2e-69 Identities = 111/457 (24%), Positives = 197/457 (43%), Gaps = 45/457 (9%) Query: 45 RRRNFAIISHPDAGKTTLTEKLLLYGGAIQQAGAVKARGEQRKVTSDWMELEKQRGISIT 104 + N +++H DAGKTTLTE LL GAI + G+V +D LE+QRGI+I Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGT----TRTDNTLLERQRGITIQ 57 Query: 105 STVLQFDYADNTINLLDTPGHQDFSEDTYRTLAAADNAVMLEDAAKGLEPQTRKLFEVCR 164 + + F + + +N++DTPGH DF + YR+L+ D A++L A G++ QTR LF R Sbjct: 58 TGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 165 MRNIPIFTFINKMDRAGRDPLLLLDEIEAELELIPWAVNWPIGSGELFRGVIDRRTRNVV 224 IP FINK+D+ G D + +I+ ++ + +V Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIK------------------------EKLSAEIV 153 Query: 225 LFTRAERG-RQASERHLHLDDPELPSLVEQELLDQALEELELLEAAGAELDLELVHAGEL 283 + + E + + +LL++ + L + + H L Sbjct: 154 IKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSL 213 Query: 284 TPVFFGSAMTNFGVRPFLDAFLEMAQRPVARSTSEGPVDPLRPSFSGFVFKLQANMDPRH 343 PV+ GSA N G+ ++ R SE G VFK++ + Sbjct: 214 FPVYHGSAKNNIGIDNLIEVITNKFYSSTHRGQSE---------LCGKVFKIE--YSEK- 261 Query: 344 RDRVAFVRVCSGRFEKDMTVRLARTGKSIRLSRPQKLFGQERSVVDDAYPGDVIGLNNPG 403 R R+A++R+ SG +VR++ K I+++ E +D AY G+++ L N Sbjct: 262 RQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKIDKAYSGEIVILQNEF 320 Query: 404 MFAIGDTLYTGSRVEYEGIPCFSPEIFSWLRNPN-PSAFKNFRKGVNELREEGAVQILYD 462 + L + + P+ P + + E+ + + + Y Sbjct: 321 -LKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPL-LRYY 378 Query: 463 TDQSKRDPILAAVGQLQLDVVQHRLENEYGVQTRLEP 499 D + + IL+ +G++Q++V L+ +Y V+ ++ Sbjct: 379 VDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKE 415
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.023 Identities = 8/47 (17%), Positives = 18/47 (38%), Gaps = 6/47 (12%) Query: 335 LIDNAFTYGLAP------VTVSLRGFENSYHIEVWDQGKGMPMDQWE 375 L++N +G+A + + + +EV + G + E Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE 309
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 98.4 bits (245), Expect = 8e-26 Identities = 44/133 (33%), Positives = 66/133 (49%), Gaps = 1/133 (0%) Query: 1 MERSSMIWVVDDDPELRQMVGTYLIDQGYDVRCLSDVKQLEARLEFQRPDLVVLDLMLPG 60 M ++ I V DDD +R ++ L GYDVR S+ L + DLVV D+++P Sbjct: 1 MTGAT-ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 61 DDGLSALRRLRDAGDDLPVVMLTARGEAVDRIIGLEQGADDYLGKPFLPRELSARIEAVL 120 ++ L R++ A DLPV++++A+ + I E+GA DYL KPF EL I L Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 121 RRRCALPAGTPLA 133 P+ Sbjct: 120 AEPKRRPSKLEDD 132
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 32.4 bits (74), Expect = 2e-04 Identities = 23/94 (24%), Positives = 45/94 (47%), Gaps = 17/94 (18%) Query: 15 FQMSEEQLKAFLEKVKADTSLQEKLKAA----ADSDAVLVIA-KDAGFSISADDLKNAQS 69 F ++E+ L+ F+++V +++ ++ + + V A +++ A ++ Sbjct: 84 FFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVF---- 139 Query: 70 EISEEELESVAGGAG--VTEAT----IDAGGGCT 97 EE + A GAG V+EAT +D GGG T Sbjct: 140 --LIEEPMAAAIGAGLPVSEATGSMVVDIGGGTT 171
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 65.8 bits (160), Expect = 3e-15 Identities = 38/178 (21%), Positives = 64/178 (35%), Gaps = 25/178 (14%) Query: 13 ALLIIDVQERLIQPVDDQ----KQIVWNIRRLIDAANALSIEMAAT----EQYPQ----- 59 LLI D+Q + ++ NIR+L + L I + T Q P Sbjct: 32 VLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDRALL 91 Query: 60 --------RLGHTIELIAKRIVHKP----YPKMSFSCVRCAETLQQFRKSGISKILLCGI 107 G E I + + K +S + L+ RK G ++++ GI Sbjct: 92 TDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGI 151 Query: 108 EAHVCVLQTAIDLISNDYQVFVAVDAIGSRRRIDYEFALRRMESVGVTLTTTESVMFE 165 AH+ L TA + D + F DA+ ++ AL T+S++ + Sbjct: 152 YAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMALEYAAGRCAFTVMTDSLLDQ 209
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 79.1 bits (195), Expect = 4e-22 Identities = 36/120 (30%), Positives = 65/120 (54%), Gaps = 14/120 (11%) Query: 9 NVLHDFTEFINRGNVVDLAVAVVVGGAFSKVVDALVKLVTIAAMDPLLRKLKVETLS--- 65 +++ +F EF RGNVVDLAV V++G AF K+V +LV + + + L+ + + + Sbjct: 2 SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61 Query: 66 -----DLPG-----GSLLVAIINFLVIAFVVFIVVRAIERFKRKQ-EVKAVAGPNTQQQL 114 D+P G + + +FL++AF +F+ ++ I + RK+ E A P ++ L Sbjct: 62 RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.4 bits (97), Expect = 2e-05 Identities = 40/246 (16%), Positives = 76/246 (30%), Gaps = 43/246 (17%) Query: 149 AGQNL--LDQGPQHYDLNGLMQQLEQRAEVSLQSSLDQKVSTELEALVEATFTSRGVRRN 206 G L L D L Q A + S EL L E +N Sbjct: 120 KGDVLLKLTALGAEADTLKTQSSLLQ-ARLEQTRYQILSRSIELNKLPELKLPDEPYFQN 178 Query: 207 SLLWQCQQQRERAEDALKTAELQRDSFESTSAELDQLEHELDLLTSDRKPALKKRRFELQ 266 E+ L+ L ++ F + + Q E L K+R E Sbjct: 179 V----------SEEEVLRLTSLIKEQFSTWQNQKYQKEL-----------NLDKKRAERL 217 Query: 267 TQQEQTRQDEAALLLYRQQLEPLQ-LRKKQLQSVLHANNQIHNEFLLCQKNLEDGSEQQT 325 T + + E + + +L+ L KQ + + L + + + Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQAIA--------KHAVLEQENKYVEAVNELR 269 Query: 326 LLKHSLSETKKQIETTQQKLNDLDQQRSDWELRGLQMRRLEELTQLKLQRESL--QRQHN 383 + K L + + +I + +++ + Q + L++L Q L + N Sbjct: 270 VYKSQLEQIESEILSAKEEYQLVTQL--------FKNEILDKLRQTTDNIGLLTLELAKN 321 Query: 384 EQQRLR 389 E+++ Sbjct: 322 EERQQA 327
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 49.3 bits (117), Expect = 7e-09 Identities = 34/148 (22%), Positives = 58/148 (39%), Gaps = 8/148 (5%) Query: 12 VQSRRILLTGASSGIGYQAAVRMHRAGHQLILPCRDRSTATATLKKLSEETAQHQQERSP 71 ++ + +TGA+ GIG A + G + + K ++ + R Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIA------AVDYNPEKLEKVVSSLKAEARHA 59 Query: 72 VSAPVMDLADLESIKHCADELLRIGQPIDTLILNAGLQYTGAAKAQLSSQGYELTIAVNH 131 + P D+ D +I + R PID L+ AG+ G LS + +E T +VN Sbjct: 60 EAFP-ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIH-SLSDEEWEATFSVNS 117 Query: 132 LGHQALSIRLLPLLDEGRSPRVVVTASE 159 G S + + + RS +V S Sbjct: 118 TGVFNASRSVSKYMMDRRSGSIVTVGSN 145
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.6 bits (69), Expect = 0.032 Identities = 37/219 (16%), Positives = 85/219 (38%), Gaps = 26/219 (11%) Query: 163 ALISVPKRQG--LIEVLDRVQSALLKISAYIARYTPLGVFAILASTTSQVSPSELPRLAI 220 A + + G ++ +++ L ++ + P G+ + T+ + + Sbjct: 287 AGLGIKLATGANALDTAKAIKAKLAELQPFF----PQGMKVLYPYDTTPFVQLSIHEVVK 342 Query: 221 YIVLQGGIAVVLTFLFLPYLVQAVIPIKAGELIKSFRTPLLIAFS-TANLLVVLPLLINQ 279 + + ++ +LFL + +IP A ++ +L AF + N L + +++ Sbjct: 343 TLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAI 402 Query: 280 G-----KQLLIEGMAR-QRSLGLEDRESRKKLAQSIELPVEVLTPLALVFPDMGRVLSLA 333 G +++E + R L +E+ +K I+ + + VLS Sbjct: 403 GLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAM----------VLSAV 452 Query: 334 FVPFAGWLTGNPLTVEQMPSFLITGLASTFLEGVLAMTF 372 F+P A + G T F IT +++ L ++A+ Sbjct: 453 FIPMA-FFGG--STGAIYRQFSITIVSAMALSVLVALIL 488
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 111 bits (279), Expect = 2e-31 Identities = 46/120 (38%), Positives = 68/120 (56%), Gaps = 6/120 (5%) Query: 97 LAADVLFDFDKANLKPSAIKSLQGVAKRIRESSRGD--VRIEGHTDSKGSNEYNQTLSEK 154 L +DVLF+F+KA LKP +L + ++ D V + G+TD GS+ YNQ LSE+ Sbjct: 217 LKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSER 276 Query: 155 RAISVRDWFVSEGGLSNVQFATKGLGELKPVVSNTTEEG---ADDPIGRQRNRRVEIIIK 211 RA SV D+ +S+ G+ + + +G+GE PV NT + A +RRVEI +K Sbjct: 277 RAQSVVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVK 335
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 25.5 bits (56), Expect = 0.039 Identities = 14/74 (18%), Positives = 33/74 (44%), Gaps = 10/74 (13%) Query: 19 MSEEQLKAFLEKVKGDTSLQEKLQAA----ADSDAVLAIA-KEAGFMISADELKKAQSEI 73 ++E+ L+ F+++V ++ ++ + + V A +E+ A E+ + Sbjct: 86 VTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREV-----FL 140 Query: 74 SEEELESAAGGRLK 87 EE + +A G L Sbjct: 141 IEEPMAAAIGAGLP 154
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 33.0 bits (75), Expect = 0.001 Identities = 21/114 (18%), Positives = 38/114 (33%), Gaps = 22/114 (19%) Query: 183 ALVPIGDVEHRLNSHYDGGALGTYGLDVGYSITPDLNASVGYYYQQGDLGDADGSGVKGR 242 + + ++D G + V Y+ITP++ + Y + ++GDA Sbjct: 121 MVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTN-NIGDA------HT 173 Query: 243 LAYNISNGLTLGANLSYDEAFDTRFTADIKYRFGSNGYGAPSKSEPAVMPAIQA 296 + NG+ + + YRFG PA P +Q Sbjct: 174 IGTRPDNGML---------------SLGVSYRFGQGEAAPVVAPAPAPAPEVQT 212
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 47.3 bits (112), Expect = 6e-08 Identities = 30/149 (20%), Positives = 48/149 (32%), Gaps = 26/149 (17%) Query: 203 GKGKYTTGEGDDVAY---MDGYGV----LSTRGGDDIVYVENTSDELW------ISAYLG 249 + YT + D G S + + + S +S G Sbjct: 278 DRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHG 337 Query: 250 EGNDMAFGGKGHQEIRGFHGNDYID--SGDDT-------DLVNGGGGADEFII----DLQ 296 + A GG G+ + G ++ + +G+D D + GG G D F+ D Sbjct: 338 VTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDST 397 Query: 297 NSGVDTILDFVHVGDKITVLDGGESSQGD 325 + D I DF DKI + Q Sbjct: 398 VAAYDWIADFQKGIDKIDLSAFRNEGQLS 426
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 37.6 bits (87), Expect = 2e-05 Identities = 20/120 (16%), Positives = 41/120 (34%), Gaps = 3/120 (2%) Query: 200 GAIADFNKAITLNPKDAAAYNNRGAVKGKSGDNQAAIADFNKAIEIDLQYADAYINRGLA 259 G IA N+ ++ + + +SG + A F +D + ++ G Sbjct: 23 GTIAMLNE---ISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGAC 79 Query: 260 KYNLGDNQGAITDYSEAIKIDPQDVFAYNNRGYVTWKLKDYQSACNDFKKAASLGSQSTA 319 + +G AI YS +D ++ + + + A + A L + T Sbjct: 80 RQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTE 139 Score = 34.9 bits (80), Expect = 2e-04 Identities = 19/119 (15%), Positives = 35/119 (29%), Gaps = 13/119 (10%) Query: 151 FLNRGLAKKNLNKYQEAIVDYNKAIVINPQLAVAYHKRGLAKVDLKDYQGAIADFNKAIT 210 FL G LN+ I+ + + Y+ A F Sbjct: 18 FLKGGGTIAMLNE-------------ISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCV 64 Query: 211 LNPKDAAAYNNRGAVKGKSGDNQAAIADFNKAIEIDLQYADAYINRGLAKYNLGDNQGA 269 L+ D+ + GA + G AI ++ +D++ + G+ A Sbjct: 65 LDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEA 123 Score = 32.6 bits (74), Expect = 0.001 Identities = 19/116 (16%), Positives = 40/116 (34%), Gaps = 3/116 (2%) Query: 96 NQGAIADFNKAIEINPQYVRAYNNRGLAKSKSGDNQGAIVDYNMAIAINPVYLYGFLNRG 155 G IA N EI+ + + + +SG + A + ++ FL G Sbjct: 21 GGGTIAMLN---EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLG 77 Query: 156 LAKKNLNKYQEAIVDYNKAIVINPQLAVAYHKRGLAKVDLKDYQGAIADFNKAITL 211 ++ + +Y AI Y+ +++ + + + A + A L Sbjct: 78 ACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133 Score = 29.1 bits (65), Expect = 0.017 Identities = 15/107 (14%), Positives = 36/107 (33%), Gaps = 4/107 (3%) Query: 75 INPKDADAYNNRGLAKSKSGDNQGAIADFNKAIEINPQYVRAYNNRGLAKSKSGDNQGAI 134 I+ + + + +SG + A F ++ R + G + G AI Sbjct: 31 ISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAI 90 Query: 135 VDYNMAIAI---NPVYLYGFLNRGLAKKNLNKYQEAIVDYNKAIVIN 178 Y+ + P + + L K L + + + + ++ + Sbjct: 91 HSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGL-FLAQELIAD 136
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 32.6 bits (74), Expect = 0.002 Identities = 20/84 (23%), Positives = 30/84 (35%), Gaps = 15/84 (17%) Query: 170 GSEGNDRLTGLPGPDLFV-------LSPGNDVITDFRIGEDSISVAGT--------PDLR 214 G G D L G G D FV D I DF+ G D I ++ + Sbjct: 372 GGAGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSAFRNEGQLSFVQDQ 431 Query: 215 FRQTGEGLLIRAGDDIRTLLLNVH 238 F G+ ++++ L +H Sbjct: 432 FTGKGQEVMLQWDAANSITNLWLH 455
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.031 Identities = 7/43 (16%), Positives = 14/43 (32%), Gaps = 5/43 (11%) Query: 72 IPDSAYKAAQERQNAQRVARLEARRAEYLSVVDQLEKQIAELQ 114 I A + + Y S ++Q+E +I + Sbjct: 249 IAKHAVLEQE-----NKYVEAVNELRVYKSQLEQIESEILSAK 286
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.4 bits (118), Expect = 2e-08 Identities = 32/274 (11%), Positives = 98/274 (35%), Gaps = 41/274 (14%) Query: 130 SAQHEQLHSELDQLKRTLRDTLAQQNNINSKQSILREELARRSSYLAQMQKLESKGYVTR 189 Q ++ Q + L A++ + ++ + S L L K + + Sbjct: 192 KEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAK 251 Query: 190 AAILQEQAQVDNLRSQIYSNKNELINLSNQLDQSYQKLGNTLSNL--------------- 234 A+L+++ + +++ K++L + +++ + ++ Sbjct: 252 HAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNI 311 Query: 235 --INQQMIFASDDVYLTQVI-PNNGE----------SVIQ-GQVVLQLSDDSLNSPILVP 280 + ++ + + + P + + V+ + ++ + + + + V Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPE--DDTLEVT 369 Query: 281 VFLGSREMAQVFPGMDALATPEGYKRSEVGGIRGRVVSMAQVPSGLED--------VHAR 332 + ++++ + G +A+ E + + G + G+V ++ +ED V Sbjct: 370 ALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN--LDAIEDQRLGLVFNVIIS 427 Query: 333 VGLKSLAQVITNREPSPTLAVLALERSGETSPLN 366 + L+ N S +AV A ++G S ++ Sbjct: 428 IEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVIS 461 Score = 33.3 bits (76), Expect = 0.002 Identities = 17/130 (13%), Positives = 43/130 (33%), Gaps = 18/130 (13%) Query: 115 GQKVPAGQLML-----------------WIQSSAQHEQLHSELDQLKRTLRDTLAQQNNI 157 G+ V G ++L +Q+ + + ++ L + Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEP 174 Query: 158 NSKQSILREELARRSSYLAQMQKLESKGYVTRAAILQEQAQVDNLRSQIYSNKNELINLS 217 + E L S Q +++ Y + +++A+ + ++I +N Sbjct: 175 YFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEK 234 Query: 218 NQLDQSYQKL 227 ++LD + L Sbjct: 235 SRLD-DFSSL 243
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 29.0 bits (65), Expect = 0.007 Identities = 12/36 (33%), Positives = 18/36 (50%) Query: 44 MRRFLVAAVFLFTTLSPAAWAEKPSVLLNTLPKEVR 79 MRR L A L ++P A+A+ P + LP + Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQ 36
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 1e-22 Identities = 33/124 (26%), Positives = 61/124 (49%), Gaps = 3/124 (2%) Query: 18 RLLVVEDDDAIRETIGEALCAEGFETILCGDGFEAVSILTSQPRHKFDLIILDVMLPGIG 77 +LV +DD AIR + +AL G++ + + + + DL++ DV++P Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD---GDLVVTDVVMPDEN 61 Query: 78 GLDICRRLREFDPKTRIFMISARDNEIDRVLGLEVGADDYLVKPFSVRELVARCRAQLRR 137 D+ R+++ P + ++SA++ + + E GA DYL KPF + EL+ L Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 138 YQER 141 + R Sbjct: 122 PKRR 125
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 26.5 bits (58), Expect = 0.035 Identities = 7/34 (20%), Positives = 13/34 (38%), Gaps = 3/34 (8%) Query: 84 KVVKSWG---FDREALNAKTRAIWSSGWRPGTAT 114 +++ + F+RE NA R + G Sbjct: 196 QILSAKPANMFEREVKNAMRRWRYEPGKPGSGIV 229
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.8 bits (67), Expect = 0.020 Identities = 29/140 (20%), Positives = 53/140 (37%), Gaps = 17/140 (12%) Query: 280 LLLYPLTAWLSDRLGRKPLLLAG-----GGMLMFGSIPLFELIHTTDPLRIFAGQLGFVI 334 P+ LSDR GR+P+LL + + P +++ RI AG G Sbjct: 57 FACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIG---RIVAGITGATG 113 Query: 335 ALATLSGGLNVANVELMPKVVRCTGLAFAYNTSMGIFGGTTPLIATWLIQGSGNPISPAY 394 A+A + ++ + + + F + G P++ + S P +P + Sbjct: 114 AVAG-AYIADITDGDERARHFGFMSACFGFGMVAG------PVLGGLMGGFS--PHAPFF 164 Query: 395 WVAGSASITLLTSIFWVRET 414 A + LT F + E+ Sbjct: 165 AAAALNGLNFLTGCFLLPES 184
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 70.6 bits (173), Expect = 7e-16 Identities = 53/273 (19%), Positives = 103/273 (37%), Gaps = 33/273 (12%) Query: 107 RELAKQQKDLQASAFLLVLDDGRYAELSAETA---LPAASSIKTAILLVALELIDSGQLS 163 ++ + L ++ +D L+A A P S+ K + L +D+G Sbjct: 27 EQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQ 86 Query: 164 WNEPLKLTKEIIGGGAGWMASKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGKDVLN 223 + ++ + + ++ K L E+ I +SDN+A NLL+ +GG L Sbjct: 87 LERKIHYRQQDLVDYSP-VSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLT 145 Query: 224 ARFNALGLSSTVVNNWLPDL------QGTNTTSSHDLARAIALVDTGKALSPRTRDLFRE 277 A +G + T ++ W +L +TT+ +A + + T + LS R++ + Sbjct: 146 AFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQ 205 Query: 278 AM-STSVSNRLLPGGFLKGLGGKQGEPDNSLLAKGYRIYNKTGDIGIAYA---DAGLIEL 333 M V+ L+ L G+ I +KTG L+ Sbjct: 206 WMVDDRVAGPLIRSV----------------LPAGWFIADKTG--AGERGARGIVALLGP 247 Query: 334 PDGS-RAVAGFMVKGPFNDPRSTELIRDMAAAM 365 + + R V ++ P + + I + AA+ Sbjct: 248 NNKAERIVVIYLRDTPASMAERNQQIAGIGAAL 280
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.029 Identities = 40/190 (21%), Positives = 58/190 (30%), Gaps = 47/190 (24%) Query: 37 VMIMGDRGTGKSTAIRALADLLPGIDVVAGDPYNSSPTDPDLQSSDVRQRIEHGESLATE 96 +MI G+ GTGK RAL D P+ + Sbjct: 163 LMITGESGTGKELVARALHDYGKR----RNGPFVA------------------------- 193 Query: 97 ERQVPMVDLPLGATEDRLCGTIDIEKALSEGVRAFEPGLLAKANRGLLYVDEVNLLDDHL 156 + M +P E L G EK G + G +A G L++DE+ + Sbjct: 194 ---INMAAIPRDLIESELFGH---EKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDA 247 Query: 157 VDVLLDSAASGWNTVEREGVSVRHPARFVLIGSGNP------EEGELRPQLLDRFGMSVE 210 LL G G + ++ + N +G R L R Sbjct: 248 QTRLLRVLQQG--EYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLN---- 301 Query: 211 VRTVRDPDLR 220 V +R P LR Sbjct: 302 VVPLRLPPLR 311
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 27.1 bits (59), Expect = 0.022 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 2/82 (2%) Query: 30 TTGGSKAKKAAEAQAKQAAEEAAAKAAAEAAAKQAAEQAAAKAAAEAAAAK--KAAEAAA 87 +KA++ A A+AK+ AEE A + AA AA A A A AA + A+ AA Sbjct: 216 AAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYAMPANGSVVATAAGRGLIQVAQGAA 275 Query: 88 SAAPAATAATPVSGEAETSQAS 109 S A A + A V G S S Sbjct: 276 SLAQAISDAIAVLGRVLASAPS 297
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 68.3 bits (167), Expect = 9e-15 Identities = 44/211 (20%), Positives = 85/211 (40%), Gaps = 29/211 (13%) Query: 108 DYNDRLDEAKALERKEQAEYETRKADHERRDNLYQQGAISADDASKYRRLYLTSRANLAA 167 + + L K+ + ++E + K +++ L++ + R + N+ Sbjct: 263 EAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN------EILDKLR---QTTDNIGL 313 Query: 168 AQERVQQRITEGSELLIRAPFSG-VITARYAEPGAFVTPTTAASATAGASSSSLVELSEG 226 + + +IRAP S V + G VT + +V + Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT--------AETLMVIVPEDDT 365 Query: 227 MEVNAKVPESDIGRIRIGQNASVRVDAFPEQRF---MARVSEIAPRAAKTENV-ISFAVK 282 +EV A V DIG I +GQNA ++V+AFP R+ + +V I A + + + + F V Sbjct: 366 LEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVI 425 Query: 283 LNLIKPSP-------QLLIGMSADVDFQTGK 306 +++ + L GM+ + +TG Sbjct: 426 ISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456 Score = 47.5 bits (113), Expect = 5e-08 Identities = 26/143 (18%), Positives = 62/143 (43%), Gaps = 15/143 (10%) Query: 56 GTLPGIVSANGEL-QAKRSVNVSPKKAGLLKELYVDQGDEVKKGEVLARMDSGDYN---- 110 G + + +ANG+L + RS + P + ++KE+ V +G+ V+KG+VL ++ + Sbjct: 78 GQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTL 137 Query: 111 ---DRLDEAKALERKEQAEYETRKADHERRDNLYQQGA---ISADDASKYRRL----YLT 160 L +A+ + + Q + + + L + +S ++ + L + T Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFST 197 Query: 161 SRANLAAAQERVQQRITEGSELL 183 + + + ++ E +L Sbjct: 198 WQNQKYQKELNLDKKRAERLTVL 220
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 30.6 bits (69), Expect = 0.019 Identities = 12/50 (24%), Positives = 25/50 (50%), Gaps = 1/50 (2%) Query: 585 GIRIDLPYLKELSIELGNTLEKLEQQAQEAAGVNFNLASPKQLGELLFET 634 ++I Y+K++S E N +Q + + + + KQ+G+ L+E Sbjct: 19 VLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEA-KQVGDDLYEV 67
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 29.0 bits (65), Expect = 0.031 Identities = 17/95 (17%), Positives = 34/95 (35%), Gaps = 6/95 (6%) Query: 113 FAVLRLNLRGAEPGRHLSAGTYAADCNSDLGPVLLRA---RQLCDQLGREG---VASRGA 166 ++ + L R ++AG Y + P ++ L G +A R Sbjct: 362 YSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYR 421 Query: 167 VPLLGAGISLGGTMLLNACLEPSHARAPGQAVLDG 201 G G ++G L+ + +++ P + DG Sbjct: 422 AFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDG 456
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.011 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 16/78 (20%) Query: 67 TGRPGTGKTTVAIRISQILHRLGYLRKGHVVTV-----TRDDLVGQYVGH------TAPK 115 TG GTGK VA + LH G R G V + RD + + GH A Sbjct: 166 TGESGTGKELVA----RALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQT 221 Query: 116 TRE-MIKRAQGGVLFIDE 132 ++A+GG LF+DE Sbjct: 222 RSTGRFEQAEGGTLFLDE 239
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 46.0 bits (109), Expect = 8e-08 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 3/95 (3%) Query: 183 GYVPVISSVAATVEGCSHNINADTVAGEIAAALEAEKLILLTDTPGILLDRDDPSS-LVH 241 G VPVI ++G I+ D ++A + A+ ++LTD G L + Sbjct: 195 GGVPVILE-DGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAALYYGTEKEQWLR 253 Query: 242 QLRLSEARQLITEG-VVAGGMTPKTECCIRALAQG 275 ++++ E R+ EG AG M PK IR + G Sbjct: 254 EVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWG 288 Score = 34.4 bits (79), Expect = 4e-04 Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 10/65 (15%) Query: 45 GRRIVIKYGGAAM----------AHANLQEAVFRDLALLVSVGVEPVVVHGGGPEINQWL 94 G+R+VI GG A+ + R +A +++ G E V+ HG GP++ L Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61 Query: 95 ERLEI 99 ++ Sbjct: 62 LHMDA 66
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 2e-21 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 3/104 (2%) Query: 20 TVAIVDDDPRVRELLKEEIQDEGHHVLSFESAETFLENSSLESIDLVLLDLMMPGMNGLE 79 T+ + DDD +R +L + + G+ V +A T + DLV+ D++MP N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 80 CLQQLHQQACHVKLPRIVVVSALSDPSKQRQALEAGAESYVIKP 123 L ++ + LP + V+SA + +A E GA Y+ KP Sbjct: 65 LLPRI--KKARPDLPVL-VMSAQNTFMTAIKASEKGAYDYLPKP 105
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 98.4 bits (245), Expect = 7e-26 Identities = 31/125 (24%), Positives = 60/125 (48%), Gaps = 2/125 (1%) Query: 7 PRTRVLLVDDEPRLTELLRLELDVEGYEVSVAEDGASGLIKARSDPSPNLIILDWNLPDF 66 +L+ DD+ + +L L GY+V + + A+ + +L++ D +PD Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDE 60 Query: 67 TGVDICQRIRSSGIKTPILMLTGHDDVTDRVKALDAGVDDYLTKPFSIEELMARL-RAMQ 125 D+ RI+ + P+L+++ + +KA + G DYL KPF + EL+ + RA+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 126 RRAEQ 130 + Sbjct: 121 EPKRR 125
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.6 bits (77), Expect = 7e-04 Identities = 24/211 (11%), Positives = 57/211 (27%), Gaps = 23/211 (10%) Query: 21 KAEDPVKILDQSVADMQADLVKLRQAVAMAIASQKRLRNQADQAEGQVR--------TWY 72 + D + L A+ AD +K + ++ A Q R + + E ++ Sbjct: 119 RKGDVLLKLTALGAE--ADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYF 176 Query: 73 ERAELALQKGEEDLAKEALTRRK----GFQESSTALTNQLKGQEGQVETLKRSLVALEGK 128 + L KE + + + + + ++ + + + Sbjct: 177 QNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSR 236 Query: 129 IAEART-KKDMLKARAQAAKAQQQLQSAVGNLGTNSAMAAFDRMEDKVQALEASSQAAAE 187 + + + A+ + + + AV L + Q A E Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLE--------QIESEILSAKEE 288 Query: 188 LAGADLESQFAALEGGNDVDDELSALRQRLE 218 + L+ D + L L Sbjct: 289 YQLVTQLFKNEILDKLRQTTDNIGLLTLELA 319
>PF01540#Adhesin lipoprotein Length = 475 Score = 29.7 bits (66), Expect = 0.037 Identities = 24/107 (22%), Positives = 46/107 (42%), Gaps = 11/107 (10%) Query: 405 QIQKMWAAKLGLKEYNSNLFEELLQLIINSKVDYTIFFRELSHIPNNLSALKKSFYIQTS 464 +++K W L E + ++L + N K+ + EL I N L K+ + Sbjct: 339 EVKKAW--SKELAEIKAEDDKKLAEE--NQKIKNGV--EELKKINNEAFELSKTVNKTIA 392 Query: 465 Q-----QIDEQWKSWLQSWRDLVLNKGSSTETSKTMKLTNPKYTWRE 506 + +ID +K L+++ D +L+K + T+ T +T E Sbjct: 393 ELEKKFKIDVSFKEQLKNFADDLLDKSRQIDEFTTVTSTQEGFTLAE 439
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 112 bits (282), Expect = 2e-36 Identities = 46/89 (51%), Positives = 63/89 (70%) Query: 2 NKADLVNLVAARTELTKTDVSLVVDAAIDTIIDSVVEGKKVSILGFGSFEPRDRSARQGL 61 NK DL+ VA TELTK D + VDA + + +G+KV ++GFG+FE R+R+AR+G Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPKTGQKIKIPAKRVPAFTAGKMFKDRVQ 90 NP+TG++IKI A +VPAF AGK KD V+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 67.9 bits (166), Expect = 2e-14 Identities = 59/262 (22%), Positives = 108/262 (41%), Gaps = 51/262 (19%) Query: 137 RLVLTAPVESYRAYRTWLNQVCTTLPVEEIALVDEPTAAAMGAGLP--PGSKLLVMDIGG 194 R+++ PV + + R + + E+ L++EP AAA+GAGLP + +V+DIGG Sbjct: 109 RVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGG 168 Query: 195 STIDLSLVALEGGEGRAAPIAQLLRFAGQDLEDSSKQALRCARVLGKAGLKLGGRDLDHW 254 T ++++++L G + +R G +++ +R G +G Sbjct: 169 GTTEVAVISLNGV-----VYSSSVRIGGDRFDEAIINYVR-----RNYGSLIGEA----- 213 Query: 255 IANHLYPDVPLSETLLNAAERLKCRLSQVDLRAEATQLEIAADSEGNEV---LP--LRLC 309 AER+K + E ++E+ G + +P L Sbjct: 214 -----------------TAERIKHEIGSAYPGDEVREIEV----RGRNLAEGVPRGFTLN 252 Query: 310 RRELEELLIARGLLNSLASLLNETLARGRGNGCEL-KDL--QGVVAVGGGAQIPLVRSWL 366 E+ E L + L + S + L + EL D+ +G+V GGGA + + L Sbjct: 253 SNEILEAL--QEPLTGIVSAVMVALEQCPP---ELASDISERGMVLTGGGALLRNLDRLL 307 Query: 367 QQQTQPAPLLTPPPIEAVAVGA 388 ++T ++ P+ VA G Sbjct: 308 MEETGIPVVVAEDPLTCVARGG 329
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 29.9 bits (67), Expect = 0.027 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 7/39 (17%) Query: 424 STVDRCIGRLLDSTGRMGGTLLITADHGNAELMQGSDGQ 462 S VD + L D+T GG L++T+ + G+DGQ Sbjct: 109 SRVDVTVSSLGDATSLRGGNLIMTS-------LSGADGQ 140
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 24.9 bits (54), Expect = 0.027 Identities = 17/71 (23%), Positives = 34/71 (47%), Gaps = 1/71 (1%) Query: 2 IISVLSWVWVASGVLLMLLVLLHSPKGGGMGGISASGSSSFTSTSSAEAT-LDRITWTCL 60 + L V++ + L+ L++L KG MG +G+S+ SS + R+T Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 61 AIFLTLAVILS 71 +F ++++L Sbjct: 61 TLFFIISLVLG 71
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 40.6 bits (95), Expect = 9e-07 Identities = 18/70 (25%), Positives = 34/70 (48%) Query: 8 IALFGTSADPPTCGHQALLEGLVAMFPKVATWASDNPMKRHCAPLEKRKALLATLVKAIA 67 A++ S DP T GH ++E +F +V NP K+ +++R +A + + Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 68 NPQLELMQEL 77 N Q++ + L Sbjct: 62 NAQVDSFEGL 71
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 27.2 bits (60), Expect = 0.046 Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 1/77 (1%) Query: 52 ELSAVVSTASSDDYAQLQRRYILATLTVSAFAVAVTALFFDLHIASSVLVGALSGVLYLR 111 E++ + ++D +L + + T + V + +IAS+ +G+L L Sbjct: 283 EVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASNGALGSLVDARGLD 342 Query: 112 LLARSVGKL-GNGSKSV 127 L V L GS V Sbjct: 343 YLLARVNLLENEGSAQV 359
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 44.5 bits (105), Expect = 5e-07 Identities = 66/388 (17%), Positives = 133/388 (34%), Gaps = 51/388 (13%) Query: 1 MLFLVCSLFYFYEFFARVAPGVLQPELMRVTGSSQGEFGLAMGMYFLAYAPSQLLVGRLL 60 +L +C L +F V V P++ + L ++ + G+L Sbjct: 15 ILIWLCILSFFSVLNEMVL-NVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 61 DRFGVRAVVAPAALVVALGCLL-FASTNNVVVLGLGRLMQGLGSSVAYLGVIYLAMIWFP 119 D+ G++ ++ ++ G ++ F + +L + R +QG G++ V+ + + P Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 120 PKRHGMVPGLTVAMGTLGASFAQYPLLILTKSWGWRIPLLVCTGAGLIIALMLWKLLPKR 179 + G GL ++ +G ++ W LL+ +I L KLL K Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITVPFLMKLLKK- 191 Query: 180 PNWFVELMREDGFDPKSPQPLASLIKEIMRD----------------------------- 210 E+ + FD K ++ I M Sbjct: 192 -----EVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDP 246 Query: 211 -------RNIWCLSLAAAGLYLPISVIGDLWGVTFL----HIHSGLSTGLSSLLTTLIFI 259 +NI + G + +V G + V ++ H S G + + + Sbjct: 247 FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSV 306 Query: 260 GFAAGGIATGHLSDRLKRRKILFITGAILSSVIAVAIALTNSAPLWLTAMLMIALGLTTG 319 G G L DR +L I LS A L + ++T +++ LG + Sbjct: 307 IIF--GYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSF 364 Query: 320 SQLLAFVMTADVAKRHNRAVKLAFVNFV 347 ++ + + + K+ ++ +NF Sbjct: 365 TKTVISTIVSSSLKQQEAGAGMSLLNFT 392
>cloacin#Cloacin signature. Length = 551 Score = 30.1 bits (67), Expect = 0.002 Identities = 19/39 (48%), Positives = 20/39 (51%), Gaps = 6/39 (15%) Query: 70 GNGGGRAWGNGGGRAVRRAWGNGGGWGNGGGGWMNGGGG 108 G+G G WG G G GNGGG GN GGG GG Sbjct: 49 GSGSGIHWGGGSGH------GNGGGNGNSGGGSGTGGNL 81 Score = 29.7 bits (66), Expect = 0.003 Identities = 19/49 (38%), Positives = 20/49 (40%), Gaps = 5/49 (10%) Query: 70 GNGGGRAWG-----NGGGRAVRRAWGNGGGWGNGGGGWMNGGGGWMNGG 113 G G W GGG WG G G GNGGG +GGG G Sbjct: 32 GASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGN 80 Score = 27.0 bits (59), Expect = 0.020 Identities = 21/60 (35%), Positives = 23/60 (38%), Gaps = 9/60 (15%) Query: 71 NGGGRAWGNGGGRAVRRAW---------GNGGGWGNGGGGWMNGGGGWMNGGYGGRGFAN 121 NGG G GGG + W G+G G GGG GGG N G G N Sbjct: 21 NGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGN 80 Score = 26.6 bits (58), Expect = 0.033 Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 1/61 (1%) Query: 56 NQLSSNERNVARAWGNGGGRAWGNGGGRAVRRAWGNGGGWGNGGGGWMNGGGGWMNGGYG 115 + S N G GGG + G+G + WG G G G GG G G NG G Sbjct: 14 HSTSGNINGGPTGLGVGGGASDGSGWS-SENNPWGGGSGSGIHWGGGSGHGNGGGNGNSG 72 Query: 116 G 116 G Sbjct: 73 G 73
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 30.5 bits (68), Expect = 0.017 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 20/83 (24%) Query: 395 EEEEALQRDAEARLAAEQATRAEEDARLRELYPLPEDEEEYDQEEPAKTMAEDENESDGQ 454 E+++AL+++ EA+ EQA +A++D R E +EE AK A EN ++ Sbjct: 143 EQKKALEKEKEAK---EQAQKAQKDKR------------EKRKEERAKNRANLENLTNAM 187 Query: 455 SD--DLSNQPDASS---EQRSNE 472 S+ +LSN + S +QR NE Sbjct: 188 SNPQNLSNNKNLSELIKQQRENE 210
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 78.4 bits (193), Expect = 9e-17 Identities = 43/143 (30%), Positives = 63/143 (44%), Gaps = 22/143 (15%) Query: 623 VMGHVDHGKTSLLDAI-----RKARVAAVEAG-------------GITQHIGAYQVEIDH 664 V+ HVD GKT+L +++ + +V+ G GIT I Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGIT--IQTGITSFQW 65 Query: 665 GGQPRKITFLDTPGHQAFTAMRARGTKVTDIAVLVVAADDGVRPQTLEAISHARAAKVPI 724 K+ +DTPGH F A R V D A+L+++A DGV+ QT R +P Sbjct: 66 ENT--KVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT 123 Query: 725 IVAINKTDKEGASPERVKQELSD 747 I INK D+ G V Q++ + Sbjct: 124 IFFINKIDQNGIDLSTVYQDIKE 146
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.032 Identities = 10/22 (45%), Positives = 13/22 (59%) Query: 32 LGLIGPNGAGKSTLLKVLAGKE 53 + L G G GKSTL+ L G + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLD 620
>PF05272#Virulence-associated E family protein Length = 892 Score = 35.4 bits (81), Expect = 4e-04 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 38 LVLVGPSGCGKSTLLRLLAGLEAPTSGEIYVG--KQPVSQLR 77 +VL G G GKSTL+ L GL+ + +G K Q+ Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIA 640
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.046 Identities = 17/62 (27%), Positives = 28/62 (45%), Gaps = 1/62 (1%) Query: 252 DPANAREAITEAQLDEQEGADILMVKPGLAYLDIIHRLSEESELPIAAYNVSGEYSMVKA 311 D A E IT E DIL+ G+ +IH LS+E + N +G ++ ++ Sbjct: 68 DSAAIDE-ITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 312 AA 313 + Sbjct: 127 VS 128
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.4 bits (123), Expect = 3e-09 Identities = 62/379 (16%), Positives = 122/379 (32%), Gaps = 91/379 (24%) Query: 49 SRITAMGRMEPQNNLIRVAPPSSRGRSRIKTLHIAEGDFVKRGQLIAEFDVV-------- 100 TA G++ + P + S +K + + EG+ V++G ++ + + Sbjct: 82 IVATANGKLTHSGRSKEIKPIEN---SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 101 ---------------------------------DERRSNLVVAEQNLAIT---KRRYEVS 124 DE V E+ L +T K ++ Sbjct: 139 TQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTW 198 Query: 125 KGESQASRIKLRRLEYELTKAER--------------DLGRYRNLYNNGAFSLSDLDAVK 170 + + + L + E L + +L + A + + + Sbjct: 199 QNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQE 258 Query: 171 LVRDKAREMLEEHKASFERIDGQ--------QVGTSLLKEGVSE------ANIKLVAAEV 216 +A L +K+ E+I+ + Q+ T L K + + NI L+ E+ Sbjct: 259 NKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLEL 318 Query: 217 SKARHYLEQAMVRAPQDGYILKLLKHVGEEVDQRGLLLMG---DTSKMVTVAEVYENDVK 273 +K + +++RAP + +L H V LM + + A V D+ Sbjct: 319 AKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIG 378 Query: 274 HIKEGQKALISSKALSS----PARGTVISVGS---------LVYKNDIIGDDPTADVDTR 320 I GQ A+I +A G V ++ LV+ I ++ + Sbjct: 379 FINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNK 438 Query: 321 VFEVRILMDASDELKKMSR 339 + M + E+K R Sbjct: 439 NIPLSSGMAVTAEIKTGMR 457
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.009 Identities = 20/77 (25%), Positives = 29/77 (37%), Gaps = 17/77 (22%) Query: 38 IVILTGPSGSGKSTLLTILGCLR----------TLQEGAASILGFPLADLSLTELSKLR- 86 V+L G G GKSTL+ L L T ++ I G +LS E++ R Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELS--EMTAFRR 655 Query: 87 ----AQIGFIFQSHNLF 99 A F + + Sbjct: 656 ADAEAVKAFFSSRKDRY 672
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 52.8 bits (126), Expect = 6e-09 Identities = 39/277 (14%), Positives = 88/277 (31%), Gaps = 6/277 (2%) Query: 249 QELMLAFETAQQGLRDLQARQQQLDEQEVRDAANLQEAEEKLAKAAANLKTLQVNVKALG 308 L L + L+ +L E+ L++ ++ L++ A+ ++ L+ KA Sbjct: 67 NTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELE-ARKADL 125 Query: 309 EDQLLGVQAELAGLETQARELERQAEQHQHEGQRLQGVRQDLSNRRKQLQQEAHSQTEDP 368 E L G + + LE + L+ + N + Sbjct: 126 EKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAK-----IKT 180 Query: 369 HRTALEDAEKNCRDAEAAVEVSRRRLGDVAGRSGAWLEQQRQRSSRRQELQSTLTPLQQE 428 E + E A+E + + + ++ ++R+ +L+ L Sbjct: 181 LEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNF 240 Query: 429 QQQLQERLRQDEERRVELEAEQQRDGTEDQQVQKQLDQLEQEWQTLLQSISDKKEQVQQA 488 +++ E + LEA Q + + +TL + + + Sbjct: 241 STADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADL 300 Query: 489 AEALAVQQRTRSRLEQEQTRLEKEIARLESRRETLQE 525 V R L ++ + +LE+ + L+E Sbjct: 301 EHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEE 337 Score = 52.0 bits (124), Expect = 1e-08 Identities = 55/320 (17%), Positives = 119/320 (37%), Gaps = 35/320 (10%) Query: 744 LRNLEQRQAALEAERSAARRSHGPLMERRHQRSQKVEELQAHQEQQQQRLNALIEKLSPL 803 ++ LE +AAL A ++ ++ M S K++ L+A + L + + L Sbjct: 143 IKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAA-------LEARQAEL 195 Query: 804 TLELQQLEQHEQEAQADGDAETWQRLQADLETADDALGTARTNRDQLLTAQQHRHLALER 863 L+ A L+A+ + + ++ Sbjct: 196 EKALEGAMNFSTADSAKIKT-----LEAEKAALAARKADLEKALEGAMNFSTADSAKIKT 250 Query: 864 LSDQQKGLEAEEKRLQEAVHALATAHAQWRDQQQELQARRQTLESQQ------------- 910 L ++ LEA + L++A+ + + L+A + LE+++ Sbjct: 251 LEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNAN 310 Query: 911 -QDLQTRFGEQRRARDAAEAEVANQRQGLQEAQWNLERLRQDRQALTEELRSGGLRLNEL 969 Q L+ R A+ EAE + + ++ + + LR+D A E + +L Sbjct: 311 RQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKL 370 Query: 970 QQALPDPPPEIPAELRSAGLEALQADLQKLQSRMEALEPVNMLALEELEQLEQRLGDLVK 1029 ++ ++ A ++L+ DL + + +E A +L LE+ +L + Sbjct: 371 EEQN---------KISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEE 421 Query: 1030 RLEVLSQEREELLLRIETVA 1049 ++ +E+ EL ++E A Sbjct: 422 SKKLTEKEKAELQAKLEAEA 441 Score = 43.5 bits (102), Expect = 5e-06 Identities = 41/306 (13%), Positives = 103/306 (33%), Gaps = 12/306 (3%) Query: 233 ARTYQELRQQLQLGRQQELMLAFETAQQGLRDLQARQQQLDEQEVRDAANLQEAEEKLAK 292 + + L+ ++ + ++ + L + ++ E E R A + E + Sbjct: 77 SFNNKALKDHNDELTEELSNAKEK-LRKNDKSLSEKASKIQELEARKADLEKALEGAMNF 135 Query: 293 AAANLKTLQV--NVKALGEDQLLGVQAELAGLETQARELERQAEQHQHEGQRLQGVRQDL 350 + A+ ++ KA + ++ L G + + + + E L+ + +L Sbjct: 136 STADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAEL 195 Query: 351 SNRRKQLQQEAHSQTEDPH---------RTALEDAEKNCRDAEAAVEVSRRRLGDVAGRS 401 + + + + D EK A ++ + Sbjct: 196 EKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEK 255 Query: 402 GAWLEQQRQRSSRRQELQSTLTPLQQEQQQLQERLRQDEERRVELEAEQQRDGTEDQQVQ 461 A +Q + + + T + + L+ E + +LE + Q Q ++ Sbjct: 256 AALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLR 315 Query: 462 KQLDQLEQEWQTLLQSISDKKEQVQQAAEALAVQQRTRSRLEQEQTRLEKEIARLESRRE 521 + LD + + L +EQ + + + +R + + +LE E +LE + + Sbjct: 316 RDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNK 375 Query: 522 TLQESR 527 + SR Sbjct: 376 ISEASR 381 Score = 42.7 bits (100), Expect = 8e-06 Identities = 66/373 (17%), Positives = 130/373 (34%), Gaps = 20/373 (5%) Query: 166 DVTRIVSMSNRDRRGLIDELAGVALFDSRIEQTRAKLDDVQERQERCRIVEQELLTTRQR 225 ++T +S + R L+ A +E +A L+ E + Sbjct: 89 ELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMN---FSTADSAKIKT 145 Query: 226 LERDCAKARTYQELRQQLQLGRQQELMLAFETAQQGLRDLQARQQQLDEQEVRDAANLQE 285 LE + R+ +L A E A A+ + L+ ++ A E Sbjct: 146 LEA-----------EKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAE 194 Query: 286 AEEKLAKAAANLKTLQVNVKALGEDQLLGVQAELAGLETQARELERQAEQHQHEGQRLQG 345 E+ L A +K L E + + A A LE + + + L+ Sbjct: 195 LEKALEGAMNFSTADSAKIKTL-EAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEA 253 Query: 346 VRQDLSNRRKQLQQEAHSQTEDPHRTALEDAEKNCRDAEAAVEVSRRRLGDVAGRSGAWL 405 + L R+ +L++ TA K +AA+E + L + A Sbjct: 254 EKAALEARQAELEKALEGAMN--FSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANR 311 Query: 406 EQQRQRSSRRQELQSTLTPLQQEQQQLQERLRQDEERRVELEAEQQRDGTEDQQVQKQLD 465 + R+ +E + L + E Q+L+E+ + E R L + +Q++ + Sbjct: 312 QSLRRDLDASREAKKQL---EAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQ 368 Query: 466 QLEQEWQTLLQSISDKKEQVQQAAEALAVQQRTRSRLEQEQTRLEKEIARLESRRETLQE 525 +LE++ + S + + + EA ++ + LEK LE ++ ++ Sbjct: 369 KLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEK 428 Query: 526 SRGTGALRLLLEA 538 + +L EA Sbjct: 429 EKAELQAKLEAEA 441 Score = 36.2 bits (83), Expect = 9e-04 Identities = 32/233 (13%), Positives = 73/233 (31%), Gaps = 19/233 (8%) Query: 303 NVKALGEDQLLGVQAELAGLETQARELERQAEQHQHEGQRLQGVRQDLSNRRKQLQQEAH 362 D L VQ E + L+ + + L+ +L+ +++ Sbjct: 43 VATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEK-- 100 Query: 363 SQTEDPHRTALEDAEKNCRDAEAAVEVSRRRLGDVAGRSGAWLEQQRQRSSRRQELQSTL 422 L +K+ + + ++ R D+ + S++ + L++ Sbjct: 101 ----------LRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEK 150 Query: 423 TPLQQEQQQLQERL-------RQDEERRVELEAEQQRDGTEDQQVQKQLDQLEQEWQTLL 475 L + L++ L D + LEAE+ +++K L+ Sbjct: 151 AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 210 Query: 476 QSISDKKEQVQQAAEALAVQQRTRSRLEQEQTRLEKEIARLESRRETLQESRG 528 I + + A A ++ T +I LE+ + L+ + Sbjct: 211 AKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQA 263
>PF03309#Bvg accessory factor Length = 271 Score = 48.6 bits (116), Expect = 5e-09 Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 32/170 (18%) Query: 91 PVWLGIDR---ALAAWGALRRAHTSGMSSSGLLVADAGTVLSLTRVTAAGDFAGGQLVPG 147 P +G DR LAA+ A +V D G+ + + V+A G+F GG + PG Sbjct: 105 PKEVGADRIVNCLAAYHKYGTA---------AIVVDFGSSICVDVVSAKGEFLGGAIAPG 155 Query: 148 LRLQLRAMEQGTQGLIDPGIGSVSAEP-FPFATAEAMRRGSLQALLGTL----------L 196 +++ A + L + T E M+ G++ G + + Sbjct: 156 VQVSSDAAAARSAAL--RRVELTRPRSVIGKNTVECMQAGAVFGFAGLVDGLVNRIRDDV 213 Query: 197 EAQREAALPLWLCGGDASVLQEALSQRGLDVVHH--PNLVLEGMVDVHDR 244 + A + + G A ++ L V H +L L+G+ V +R Sbjct: 214 DGFSGADVAVVATGHTAPLV-----LPDLRTVEHYDRHLTLDGLRLVFER 258
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.017 Identities = 9/27 (33%), Positives = 14/27 (51%), Gaps = 1/27 (3%) Query: 20 VVGVGRF-GSAVCRELMQNGADVLAVD 45 V G F G V + L++ G V+ +D Sbjct: 5 VTGAAGFIGFHVSKRLLEAGHQVVGID 31
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.024 Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 4/43 (9%) Query: 352 EPGDR----IAFIGPNGAGKSTLLRLIMGLEAADDGRASLGEH 390 EPG + + G G GKSTL+ ++GL+ D +G Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTG 632
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 77.0 bits (189), Expect = 9e-18 Identities = 36/180 (20%), Positives = 62/180 (34%), Gaps = 36/180 (20%) Query: 119 ERGQGSGVIFSAEGLVLTNAHVVEKTDQLMVGL------------PDGRRVPGRLVGQDK 166 SGV+ + +LTN HVV+ T L P+G ++ Sbjct: 100 GTFIASGVVV-GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSG 158 Query: 167 ITDLAVVQL----DGSGPW---PTAPLGDSDQLRVGDWAIAVGNPFGLENTVTLGIVSNL 219 DLA+V+ A + ++ + +V G P T+ Sbjct: 159 EGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDK-PVATMW----- 212 Query: 220 NRNVSQLGISGKRLDLIQTDAAINPGNSGGPLLNSEGNVVGINTLVRSGPGAGLGFAIPI 279 S+ I+ + + +Q D + GNSG P+ N + V+GI+ G+ Sbjct: 213 ---ESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW-------GGVPNEFNG 262
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 399 bits (1027), Expect = e-139 Identities = 156/439 (35%), Positives = 255/439 (58%), Gaps = 17/439 (3%) Query: 13 EVISQLVRNPELRGRVLTTLGLLLFIRLGIYIPMPGIDRVAFQSFLQQ---GGQLIGFLD 69 ++ R P+LR ++L TL +++ R+G +IP+PG+D Q +++ L G ++ Sbjct: 3 TAFARAFRTPDLRKKLLFTLAIIVVYRVGTHIPIPGVDYKNVQQCVREASGNQGLFGLVN 62 Query: 70 IFTGGGISTLGIFALGILPFINASIILQLLTAALPQLEDLQKNEGEAGRRKIAQITRYVA 129 +F+GG + + IFALGI+P+I ASIILQLLT +P+LE L+K EG+AG KI Q TRY+ Sbjct: 63 MFSGGALLQITIFALGIMPYITASIILQLLTVVIPRLEALKK-EGQAGTAKITQYTRYLT 121 Query: 130 LGWGLVQSVIFALILRQYAVEGLSEV----------VFVVQTALALVTGSMIVMWMSEII 179 + ++Q R + G V + + + G+ +VMW+ E+I Sbjct: 122 VALAILQGTGLVATARSAPLFGRCSVGGQIVPDQSIFTTITMVICMTAGTCVVMWLGELI 181 Query: 180 TDRGIGQGASLVIFLNIVATLPKALASTIEKAQTGDRGDVVGIIVLVMVFLMTIVGIIFV 239 TDRGIG G S+++F++I AT P AL + ++ G ++ V L+ + ++FV Sbjct: 182 TDRGIGNGMSILMFISIAATFPSALWAIKKQGTLAGGWIEFGTVIAV--GLIMVALVVFV 239 Query: 240 QEGSRRLPIVSAKRQIGGTNLLPNRQSYLPLKLNAGGVMPIIFASALIFLPITIANFTKN 299 ++ RR+P+ AKR IG + +Y+PLK+N GV+P+IFAS+L+++P +A F Sbjct: 240 EQAQRRIPVQYAKRMIGRRSYG-GTSTYIPLKVNQAGVIPVIFASSLLYIPALVAQFAGG 298 Query: 300 PLLIRAASTLNPSAANPWPYALVFFALIVGFSYFYASLTINPIDIATNLKRGGVAIPGVR 359 ++ N + + Y + +F LIV F++FY +++ NP ++A N+K+ G IPG+R Sbjct: 299 NSGWKSWVEQNLTKGDHPIYIVTYFLLIVFFAFFYVAISFNPEEVADNMKKYGGFIPGIR 358 Query: 360 PGSATANYLSGVQNRLTLLGGLFLGAVAIIPAAVERATNVQTFQGLGATSLLILVGVAID 419 G TA YLS V NR+T G L+LG +A++P G TS+LI+VGV ++ Sbjct: 359 AGRPTAEYLSYVLNRITWPGSLYLGLIALVPTMALVGFGASQNFPFGGTSILIIVGVGLE 418 Query: 420 TAKQVQTYVISQRYEGLVR 438 T KQ+++ + + YEG +R Sbjct: 419 TVKQIESQLQQRNYEGFLR 437
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 326 bits (837), Expect = e-112 Identities = 101/372 (27%), Positives = 169/372 (45%), Gaps = 22/372 (5%) Query: 29 AWVEVNPAAVEANCRSLRRHLCESCALMAVVKADGYGHGALTVARAALQGGAKSLGVATL 88 ++ A++ N +R+ + + +VVKA+ YGHG + A G + L Sbjct: 5 IQASLDLQALKQNLSIVRQAATHAR-VWSVVKANAYGHGIERIWSAI--GATDGFALLNL 61 Query: 89 QEGIELRQAGHNAPVLVLGNLTHSEDLKACLHWQLMPTLSSMREALLCQNLADGSGRQFR 148 +E I LR+ G P+L+L H++DL+ +L + S + QN Sbjct: 62 EEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNAR--LKAPLD 119 Query: 149 IQLKIDTGMTRLGCELKEAPMLVEAIGHLNQLELKGIYSHLALADGDLQGKAAMVTDQQQ 208 I LK+++GM RLG + + + + + + + SH A A+ G Sbjct: 120 IYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAE-HPDG-----ISGAM 173 Query: 209 QHFETVLRTLPEQHNGFTRHLANSAGTLRDRGLHYDMVRVGLALYGHSPNLQLQ--GKVD 266 E L R L+NSA TL H+D VR G+ LYG SP+ Q + Sbjct: 174 ARIEQAAEGLE-----CRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTG 228 Query: 267 LQPALSVKARVTLIRDVPAGVGVSYGHRFTTRRPSRLAVVGIGYADGVSRSLSGQISAIA 326 L+P +++ + + ++ + AG V YG R+T R R+ +V GYADG R + Sbjct: 229 LRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLV 288 Query: 327 DGQLLPQVGAITMDQLVLDATNHPDLEVGSIVTLLGKDGDACITPQQWSDLSGSIPWEVL 386 DG VG ++MD L +D T P +G+ V L GK+ I + +G++ +E++ Sbjct: 289 DGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKE----IKIDDVAAAAGTVGYELM 344 Query: 387 CSFKHRLPRLVI 398 C+ R+P + + Sbjct: 345 CALALRVPVVTV 356
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 29.0 bits (65), Expect = 0.022 Identities = 22/119 (18%), Positives = 42/119 (35%), Gaps = 16/119 (13%) Query: 178 RNALTTAATARLLESVMTDALVSPLACKRLRQLLSRSIDLMQRKADPENQV-DGFLGEGL 236 R+ T A+ A L ++T +S + ++L Q + ++V + L Sbjct: 174 RDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVD------------DRVAGPLIRSVL 221 Query: 237 PVGSRLWSKAGWMSQ-ARHDAAWWSLQGGRPMLLVVFTQGRE--RANDTTLLPAIAREL 292 P G + K G + AR A ++V++ + A + I L Sbjct: 222 PAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAAL 280
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 43.2 bits (101), Expect = 2e-06 Identities = 22/71 (30%), Positives = 34/71 (47%) Query: 387 PETELESGAELKPEAEPESDLNPTPDLEPNPDPDSALKPTPDLEPNPDPDSALKPTPDLE 446 P +L G+ P A+P +++P + NP P+ P+ EP+PD + P D + Sbjct: 311 PRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQ 370 Query: 447 PNPDPDSALEP 457 P PDS P Sbjct: 371 PGTRPDSPAVP 381 Score = 42.4 bits (99), Expect = 4e-06 Identities = 41/152 (26%), Positives = 60/152 (39%), Gaps = 11/152 (7%) Query: 390 ELESGAELKPEAEPESDLNPT------PDLEPNPDPDSALKPTPDLEPNPDPDSALKPTP 443 +LE LK +A P+ + T +E P + P D NP A Sbjct: 239 KLEEILSLKVDANPDKYIKATGYPGYSEKVEVAPGTKVNMGPVTDRNGNPVQVVATFGR- 297 Query: 444 DLEPNPDPDSALEPTLDLEPNPDPDSALKPTPDLEP--NPDPDSALEPTPDLEPNPDPDS 501 D + N D + P DL P +P P++ P NP + A P PNP+PD Sbjct: 298 DSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDP 357 Query: 502 ALEPTPDLEPNAELEPKLKADAAQASPAPNSQ 533 L PD P+ + +P + D+ PN + Sbjct: 358 DL--NPDANPDTDGQPGTRPDSPAVPDRPNGR 387
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 685 bits (1769), Expect = 0.0 Identities = 172/670 (25%), Positives = 294/670 (43%), Gaps = 63/670 (9%) Query: 9 RVRNIGIAAHIDAGKTTCTERILFYSGVVHKMGEVHDGAAVTDWMAQERERGITITAAAI 68 ++ NIG+ AH+DAGKTT TE +L+ SG + ++G V G TD ER+RGITI Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 STTWNDHRINIIDTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVWRQADRYSV 128 S W + ++NIIDTPGH+DF EV RS+ VLDG I + A GVQ Q+ ++ + + Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 129 PRMVFVNKMDRTGADFLKVHGQIKNRLKANAIPIQLPIGAEGDLSGIIDLVKNKAFIYKD 188 P + F+NK+D+ G D V+ IK +L A + Q K +Y + Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ------------------KVELYPN 163 Query: 189 DLGKEIEETEIPDHMKEIAAEWRSKLMECVAETDEELIEVFLETEELSEAQLASGIREGV 248 E+E +W + V E +++L+E ++ + L +L Sbjct: 164 MCVTNFTESE----------QW-----DTVIEGNDDLLEKYMSGKSLEALELEQEESIRF 208 Query: 249 LNHGLVPLLCGSAFKNKGVQLLLDAVVDYLPAPVDVPPIQGLLPNGKEAVRPSDDNAPFS 308 N L P+ GSA N G+ L++ + + + + Sbjct: 209 HNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH------------------RGQSELC 250 Query: 309 ALAFKVMSDPYG-KLTFVRMYSGVLEKGSYVLNSTKNEKERISRLIILKADDREEVDALR 367 FK+ +L ++R+YSGVL V S K EK +I+ + + ++D Sbjct: 251 GKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEK-EKIKITEMYTSINGELCKIDKAY 309 Query: 368 AGDLGAVLG--LK-NTTTGDTLCTTDDPIVLETLYIPEPVISVAVEPKTKGDMEKLSKAL 424 +G++ + LK N+ GDT E + P P++ VEP E L AL Sbjct: 310 SGEIVILQNEFLKLNSVLGDTKLLPQR----ERIENPLPLLQTTVEPSKPQQREMLLDAL 365 Query: 425 LSLAEEDPTFRVSTDPETSQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYRETIR 484 L +++ DP R D T + +++ +G++ +E+ + ++ VE I P V Y E R Sbjct: 366 LEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYME--R 423 Query: 485 ASSKGEGKFARQTGGKGQYGHVVIEMEPGEPGSGFEFVNKIVGGIVPKEYIKPAESGMRE 544 K E + + + + + P GSG ++ + + G + + + G+R Sbjct: 424 PLKKAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRY 483 Query: 545 TCESGVIAGYPLIDVKVTMVDGSYHDVDSSEMAFKIAGSMAFKDGVKKCNPVLLEPMMKV 604 CE G + G+ + D K+ G Y+ S+ F++ + + +KK LLEP + Sbjct: 484 GCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSF 542 Query: 605 EVEIPEDFLGAIIGDLSSRRGQVEGQSIDDGLSKVQSKVPLAEMFGYATQLRSMTQGRGI 664 ++ P+++L D + + + + ++P + Y + L T GR + Sbjct: 543 KIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSV 602 Query: 665 FSMEFSHYEE 674 E Y Sbjct: 603 CLTELKGYHV 612
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 82.2 bits (203), Expect = 4e-19 Identities = 55/203 (27%), Positives = 96/203 (47%), Gaps = 10/203 (4%) Query: 13 VNIGTIGHVDHGKTTLTAAI---TSVLAKKGQAKVQDYAEIDGAPEERERGITINTAHVE 69 +NIG + HVD GKTTLT ++ + + + G D ER+RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGT-TRTDNTLLERQRGITIQTGITS 62 Query: 70 YETDGRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAATDGPMAQTKEHILLAKQVGVP 129 ++ + +D PGH D++ + + +DGAIL+ +A DG AQT+ +++G+P Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 130 ALVVALNKCDMVDDEEIIELVEMEIRELLSSYDFPGDDIPIVQVSGLKAIEGEAEWEAKI 189 + +NK D + + V +I+E LS+ + + + +W+ I Sbjct: 123 TIFF-INKIDQNGID--LSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVI 179 Query: 190 ---DELMEAVDASIPEPEREIEK 209 D+L+E + E+E+ Sbjct: 180 EGNDDLLEKYMSGKSLEALELEQ 202
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 36.6 bits (84), Expect = 3e-04 Identities = 22/126 (17%), Positives = 42/126 (33%), Gaps = 10/126 (7%) Query: 518 LIEPPPENDNFLVRVVRPGEDAESVLEEAREQLSASSNRRRRRGRGGARGAGRGAPEASV 577 PPP P E E+V E ++++ S + + + A EA Sbjct: 1023 APVPPPAP-------ATPSETTETVAENSKQE-SKTVEKNEQDATETTAQNREVAKEAKS 1074 Query: 578 ETPSSNGTEVVVQQAKVVAKNEPLSVQITPLEVDHSSSSASVETVSSISEPQESEPEDPR 637 ++ T V Q + + + T A VET + P+ + P+ Sbjct: 1075 NVKANTQTNEVAQSGSETKETQTTETKETATV--EKEEKAKVETEKTQEVPKVTSQVSPK 1132 Query: 638 RRRRRS 643 + + + Sbjct: 1133 QEQSET 1138
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 32.1 bits (73), Expect = 0.008 Identities = 11/74 (14%), Positives = 24/74 (32%), Gaps = 4/74 (5%) Query: 488 AFQALRGVKVNFTDVRLSAMEDFVGRGDRRLSSVIEAAWRAGGGMDAWFEALDRTYEAWV 547 + L D + + + + +I + + EA+ + + + Sbjct: 114 IIKVLNKQGSGQYDWIIQGIYYAIEQK----VDIISMSLGGPEDVPELHEAVKKAVASQI 169 Query: 548 WAIAAAGLEGRYRD 561 + AAG EG D Sbjct: 170 LVMCAAGNEGDGDD 183
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 44.1 bits (104), Expect = 3e-07 Identities = 16/97 (16%), Positives = 34/97 (35%) Query: 7 AVALHKQGELDKAEAIYQQVLAVDVNNFYALNFCGSIKREKKRFDEGIDFLSRAISLQPD 66 A ++ G+ + A ++Q + +D + G+ ++ ++D I S + Sbjct: 43 AFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIK 102 Query: 67 NPDAIYNLGNVFKDSERWDEAISCYEKTLGLRAESPE 103 P ++ EA S L A+ E Sbjct: 103 EPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTE 139 Score = 39.9 bits (93), Expect = 6e-06 Identities = 22/124 (17%), Positives = 41/124 (33%), Gaps = 11/124 (8%) Query: 47 KKRFDEGIDFLSRAISLQPDNPDAIYNLGNVFKDSERWDEAISCYEKTLGLRAESPEALN 106 ++++ L + LG + ++D AI Y + + P Sbjct: 49 SGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPF 108 Query: 107 NLGICLKEVERFEYSEIVLRRVVSMQPGLAGAWLNLGNTFKEQEKYSEAKASYRNAIDLK 166 + CL + +E GL A + + E ++ S +S AI LK Sbjct: 109 HAAECLLQKGELAEAE----------SGLFLAQELIADK-TEFKELSTRVSSMLEAIKLK 157 Query: 167 PDFE 170 + E Sbjct: 158 KEME 161 Score = 38.4 bits (89), Expect = 3e-05 Identities = 24/160 (15%), Positives = 56/160 (35%), Gaps = 23/160 (14%) Query: 54 IDFLSRAISLQ------PDNPDAIYNLGNVFKDSERWDEAISCYEKTLGLRAESPEALNN 107 FL ++ D + +Y+L S ++++A ++ L Sbjct: 16 ESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLG 75 Query: 108 LGICLKEVERFEYSEIVLRRVVSMQPGLAGAWLNLGNTFKEQEKYSEAKASYRNAIDL-- 165 LG C + + +++ + M + ++ + +EA++ A +L Sbjct: 76 LGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIA 135 Query: 166 -KPDFEAAYFALGLVLKEEGKVEEAIASYRKAIELKPDFA 204 K +F+ L ++S +AI+LK + Sbjct: 136 DKTEFK--------ELSTR------VSSMLEAIKLKKEME 161 Score = 35.3 bits (81), Expect = 2e-04 Identities = 17/85 (20%), Positives = 28/85 (32%) Query: 141 NLGNTFKEQEKYSEAKASYRNAIDLKPDFEAAYFALGLVLKEEGKVEEAIASYRKAIELK 200 +L + KY +A ++ L + LG + G+ + AI SY + Sbjct: 41 SLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMD 100 Query: 201 PDFADVYFALGLVLKEAGEFEAARQ 225 F L + GE A Sbjct: 101 IKEPRFPFHAAECLLQKGELAEAES 125 Score = 29.9 bits (67), Expect = 0.015 Identities = 14/88 (15%), Positives = 30/88 (34%), Gaps = 6/88 (6%) Query: 144 NTFKEQEKYSEAKASYRNAIDLK------PDFEAAYFALGLVLKEEGKVEEAIASYRKAI 197 T QE ++ + + D ++L + GK E+A ++ Sbjct: 4 ETTDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALC 63 Query: 198 ELKPDFADVYFALGLVLKEAGEFEAARQ 225 L + + LG + G+++ A Sbjct: 64 VLDHYDSRFFLGLGACRQAMGQYDLAIH 91
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 43.8 bits (103), Expect = 5e-07 Identities = 28/143 (19%), Positives = 52/143 (36%), Gaps = 17/143 (11%) Query: 205 LAPESPELHLNFASALKKEGKVEEAIASCRNAIELRPDFEAAYFGLGIVLKENGEFEEAK 264 ++ ++ E + A + GK E+A + L + GLG + G+++ A Sbjct: 31 ISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAI 90 Query: 265 ASYRKAIDLKPDFADAYLNLGHVFKDHGEAEEAKASYRTAIDL---KPDFADAYLNLGNI 321 SY + + GE EA++ A +L K +F Sbjct: 91 HSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEF--------KE 142 Query: 322 LKEEGDVEEAIASYRKAIELKPD 344 L ++S +AI+LK + Sbjct: 143 LSTR------VSSMLEAIKLKKE 159 Score = 43.4 bits (102), Expect = 6e-07 Identities = 25/134 (18%), Positives = 47/134 (35%), Gaps = 5/134 (3%) Query: 8 QQQQAAVKAYQSKDLDAAEAICIQILSVNPKEPNSLHLLGCIYKDRGNLQQAFDLIQASI 67 Q+ Q A++++ A + ++ L+ L G + A + QA Sbjct: 9 QEYQLAMESFLKGGGTIA-----MLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALC 63 Query: 68 REDDSTPIPFINLGNILVMVGQHEEAARIFQQSLQRNQQIPESWFCFGNALREIGNVQEA 127 D F+ LG +GQ++ A + + + P F L + G + EA Sbjct: 64 VLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEA 123 Query: 128 KQAYRNTLQLNAAH 141 + +L A Sbjct: 124 ESGLFLAQELIADK 137 Score = 42.6 bits (100), Expect = 1e-06 Identities = 23/111 (20%), Positives = 45/111 (40%), Gaps = 3/111 (2%) Query: 238 ELRPDFEAAYFGLGIVLKENGEFEEAKASYRKAIDLKPDFADAYLNLGHVFKDHGEAEEA 297 E+ D + L ++G++E+A ++ L + +L LG + G+ + A Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLA 89 Query: 298 KASYRTAIDLKPDFADAYLNLGNILKEEGDVEEAIASYRKAIEL---KPDF 345 SY + + L ++G++ EA + A EL K +F Sbjct: 90 IHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEF 140 Score = 40.7 bits (95), Expect = 6e-06 Identities = 19/95 (20%), Positives = 34/95 (35%) Query: 273 LKPDFADAYLNLGHVFKDHGEAEEAKASYRTAIDLKPDFADAYLNLGNILKEEGDVEEAI 332 + D + +L G+ E+A ++ L + +L LG + G + AI Sbjct: 31 ISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAI 90 Query: 333 ASYRKAIELKPDFVDAYLNLGTVLNDEGEVEEARQ 367 SY + + L +GE+ EA Sbjct: 91 HSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAES 125 Score = 37.6 bits (87), Expect = 6e-05 Identities = 26/146 (17%), Positives = 44/146 (30%), Gaps = 17/146 (11%) Query: 170 EASPQDVNLRINYGKLLEDKYEYNAALEQYRFALLLAPESPELHLNFASALKKEGKVEEA 229 E S + + +Y A + ++ +L L + + G+ + A Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLA 89 Query: 230 IASCRNAIELRPDFEAAYFGLGIVLKENGEFEEAKASYRKAIDLKPDFADAYLNLGHVFK 289 I S + F L + GE EA++ A +L Sbjct: 90 IHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL--------------IA 135 Query: 290 DHGEAEEAKA---SYRTAIDLKPDFA 312 D E +E S AI LK + Sbjct: 136 DKTEFKELSTRVSSMLEAIKLKKEME 161 Score = 36.8 bits (85), Expect = 1e-04 Identities = 16/97 (16%), Positives = 28/97 (28%) Query: 13 AVKAYQSKDLDAAEAICIQILSVNPKEPNSLHLLGCIYKDRGNLQQAFDLIQASIREDDS 72 A YQS + A + + ++ + LG + G A D Sbjct: 43 AFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIK 102 Query: 73 TPIPFINLGNILVMVGQHEEAARIFQQSLQRNQQIPE 109 P + L+ G+ EA + + E Sbjct: 103 EPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTE 139
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 46.8 bits (111), Expect = 5e-08 Identities = 29/145 (20%), Positives = 54/145 (37%), Gaps = 17/145 (11%) Query: 205 LAPESPELHLNFASALKKEGKVEEAIASCRNAIELRPDFEAAYFGLGIVLKENGEFEEAK 264 ++ ++ E + A + GK E+A + L + GLG + G+++ A Sbjct: 31 ISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAI 90 Query: 265 ASYRKAIDLKPDFADAYLNLGNILKENGEFEEAKASYRTAIDL---KPDFADAYLNLGNI 321 SY + + L + GE EA++ A +L K +F Sbjct: 91 HSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEF--------KE 142 Query: 322 LKEEGDVEEAIASYRKAIELKPDFA 346 L ++S +AI+LK + Sbjct: 143 LSTR------VSSMLEAIKLKKEME 161 Score = 45.7 bits (108), Expect = 1e-07 Identities = 29/144 (20%), Positives = 57/144 (39%), Gaps = 17/144 (11%) Query: 238 ELRPDFEAAYFGLGIVLKENGEFEEAKASYRKAIDLKPDFADAYLNLGNILKENGEFEEA 297 E+ D + L ++G++E+A ++ L + +L LG + G+++ A Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLA 89 Query: 298 KASYRTAIDLKPDFADAYLNLGNILKEEGDVEEAIASYRKAIEL---KPDFADAYLNLGN 354 SY + + L ++G++ EA + A EL K +F Sbjct: 90 IHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEF--------K 141 Query: 355 ILKDKGDVGQAIASYRKAIDLKPD 378 L + ++S +AI LK + Sbjct: 142 ELSTR------VSSMLEAIKLKKE 159 Score = 42.6 bits (100), Expect = 1e-06 Identities = 25/134 (18%), Positives = 47/134 (35%), Gaps = 5/134 (3%) Query: 8 QQQQAAVKAYQSKDLDAAEAICIQILSVNPKEPNALHLLGCIYKDRGNLQQAFDLIQASI 67 Q+ Q A++++ A + ++ L+ L G + A + QA Sbjct: 9 QEYQLAMESFLKGGGTIA-----MLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALC 63 Query: 68 REDDSTPIPFINLGNILVMVGQHEEAARIFQQSLQRNQQIPESWFCFGNALREIGNVQEA 127 D F+ LG +GQ++ A + + + P F L + G + EA Sbjct: 64 VLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEA 123 Query: 128 KQAYRNTLQLNAAH 141 + +L A Sbjct: 124 ESGLFLAQELIADK 137 Score = 41.5 bits (97), Expect = 4e-06 Identities = 23/112 (20%), Positives = 45/112 (40%), Gaps = 3/112 (2%) Query: 273 LKPDFADAYLNLGNILKENGEFEEAKASYRTAIDLKPDFADAYLNLGNILKEEGDVEEAI 332 + D + +L ++G++E+A ++ L + +L LG + G + AI Sbjct: 31 ISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAI 90 Query: 333 ASYRKAIELKPDFADAYLNLGNILKDKGDVGQAIASYRKAIDL---KPDFSE 381 SY + + L KG++ +A + A +L K +F E Sbjct: 91 HSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEFKE 142 Score = 39.9 bits (93), Expect = 1e-05 Identities = 14/78 (17%), Positives = 26/78 (33%) Query: 307 LKPDFADAYLNLGNILKEEGDVEEAIASYRKAIELKPDFADAYLNLGNILKDKGDVGQAI 366 + D + +L + G E+A ++ L + +L LG + G AI Sbjct: 31 ISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAI 90 Query: 367 ASYRKAIDLKPDFSEAYY 384 SY + + Sbjct: 91 HSYSYGAIMDIKEPRFPF 108 Score = 38.4 bits (89), Expect = 4e-05 Identities = 26/146 (17%), Positives = 46/146 (31%), Gaps = 17/146 (11%) Query: 170 EASPQDVNLRINYGKLLEDKYEYNAALEQYRFALLLAPESPELHLNFASALKKEGKVEEA 229 E S + + +Y A + ++ +L L + + G+ + A Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLA 89 Query: 230 IASCRNAIELRPDFEAAYFGLGIVLKENGEFEEAKASYRKAIDLKPDFADAYLNLGNILK 289 I S + F L + GE EA++ A +L + Sbjct: 90 IHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL--------------IA 135 Query: 290 ENGEFEEAKA---SYRTAIDLKPDFA 312 + EF+E S AI LK + Sbjct: 136 DKTEFKELSTRVSSMLEAIKLKKEME 161 Score = 36.8 bits (85), Expect = 1e-04 Identities = 16/97 (16%), Positives = 28/97 (28%) Query: 13 AVKAYQSKDLDAAEAICIQILSVNPKEPNALHLLGCIYKDRGNLQQAFDLIQASIREDDS 72 A YQS + A + + ++ + LG + G A D Sbjct: 43 AFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIK 102 Query: 73 TPIPFINLGNILVMVGQHEEAARIFQQSLQRNQQIPE 109 P + L+ G+ EA + + E Sbjct: 103 EPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTE 139
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 31.4 bits (71), Expect = 0.005 Identities = 32/177 (18%), Positives = 59/177 (33%), Gaps = 24/177 (13%) Query: 119 YAISASTRFKGTNHELNASASFDFDKSVDAESVSTIDTNQGAFSIRYDRILSSTKWSAYA 178 + +T F+ N L+ S + +A +I + L S S + Sbjct: 562 FQAGLNTAFEDINWTLSYS------LTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWR 615 Query: 179 STDYTYNALNDVGVNTNVFSVGVGYKVLDHKKLSLRVSLGPSLIWFDGGSGCSTGDYVSD 238 +Y+ +D+ GV +L+ LS V G + GG ++G Sbjct: 616 HASASYSMSHDLNGRMTN-LAGVYGTLLEDNNLSYSVQTG-----YAGGGDGNSGSTGY- 668 Query: 239 GIALGKYCGEIIPSGTIGAAIEWDVNNKFRLSIKNQLTGSFV---NGMAAGNDLSGT 292 A Y G G ++ + + ++G + NG+ G L+ T Sbjct: 669 --ATLNYRG---GYGNANIGY--SHSDDIK-QLYYGVSGGVLAHANGVTLGQPLNDT 717
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.5 bits (76), Expect = 0.003 Identities = 32/164 (19%), Positives = 42/164 (25%), Gaps = 18/164 (10%) Query: 77 HQRLLAGQGWGNSPLAAVALKLQAQTAERLGEKSKANHLWQSLLKRFPNTTTAADAYYSL 136 LAG+ + SP Q RL E LW L + A Sbjct: 734 LHLYLAGERYFPSPEDEEIYFRPEQ-ELRLVETGVQGRLWALLTREGAPAAEGAAQKGYS 792 Query: 137 GRHNPELRQQLLQQHPAHPAALASAIELDTSNSRHQRAIHLTRW--GVFWPGAAEVLRSA 194 L+Q A+ D S + W W E LR Sbjct: 793 VNTTFVTIADLVQ-----------ALGADPGKSSPMLEGQVRDWLNENGW----EYLRET 837 Query: 195 CSAPARNGHSNQERQELALGLAQLGDGRTALSCLQEQPPDPAAA 238 R Q + + Q+QP +PAAA Sbjct: 838 SGQRRRGYMRPQVWPPVIAEDKEADQAHAPGDQDQQQPVEPAAA 881
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 43.9 bits (103), Expect = 9e-07 Identities = 28/118 (23%), Positives = 46/118 (38%) Query: 76 ELDDLQAKLQQSRDALNSSRSAQFNAELDLKQARSDSNQVQNELKQAKKRATALRNELAP 135 AK++ + + Q E L+ A + S ++K + AL E A Sbjct: 240 FSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKAD 299 Query: 136 LQKQRQQLEAERARLSRDISKKDADIRRTEVELANVRSRISAAEKELKQLETNLIALR 193 L+ Q Q L A R L RD+ ++ E E + + +E + L +L A R Sbjct: 300 LEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASR 357 Score = 42.7 bits (100), Expect = 2e-06 Identities = 27/111 (24%), Positives = 48/111 (43%) Query: 76 ELDDLQAKLQQSRDALNSSRSAQFNAELDLKQARSDSNQVQNELKQAKKRATALRNELAP 135 L+ L SR+A + E K + + ++ +L +++ L E Sbjct: 310 NRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQK 369 Query: 136 LQKQRQQLEAERARLSRDISKKDADIRRTEVELANVRSRISAAEKELKQLE 186 L++Q + EA R L RD+ ++ E L S+++A EK K+LE Sbjct: 370 LEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELE 420 Score = 37.4 bits (86), Expect = 1e-04 Identities = 37/161 (22%), Positives = 74/161 (45%), Gaps = 7/161 (4%) Query: 76 ELDDLQAKLQQSRDALNSSR---SAQFNAELDLKQARSDSNQVQNELKQAKKRA-TALRN 131 L+ +A L+ LN++R +A + K+ +Q E + + + +LR Sbjct: 292 ALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRR 351 Query: 132 ELAPLQKQRQQLEAERARLSRDISKKDADIRRTEVELANVRSRISAAEKELKQLETNLIA 191 +L ++ ++QLEAE +L +A + +L R EK L++ + L A Sbjct: 352 DLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAA 411 Query: 192 LRRGDVVLSSGQQLA---AATLRLDNPSQAKAVIDRLLQEA 229 L + + L ++L A L+ ++AKA+ ++L ++A Sbjct: 412 LEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQA 452 Score = 29.3 bits (65), Expect = 0.033 Identities = 21/119 (17%), Positives = 42/119 (35%), Gaps = 7/119 (5%) Query: 76 ELDDLQAKLQQSRDALNSSRSAQFNAELDLKQARSDSNQVQNELKQAKKRATALRNELAP 135 L D +L + + + + + +L++A + N Sbjct: 82 ALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALE---GAMNFSTA 138 Query: 136 LQKQRQQLEAERARLSRDISKKDADIRRTEVELANVRSRISAAEKELKQLETNLIALRR 194 + + LEAE+A L + + AD+ + N + SA K L+ + L A + Sbjct: 139 DSAKIKTLEAEKAAL----AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQA 193
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 29.0 bits (65), Expect = 0.049 Identities = 35/195 (17%), Positives = 68/195 (34%), Gaps = 32/195 (16%) Query: 26 RQLVIAAAFGVGAAY---DAYNYAYVLPGFLLILLGGINGPFHSAMVSVLSRRPRQESAH 82 +++V A +A + Y +LI PF A+ S Sbjct: 27 KEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQSYLPFSQAL-----------SYV 75 Query: 83 VLAALNTMVSAALLLLTALLVLAANPLITLVGPGLSPELHRIAVVQLQVMAPMALLAGLI 142 V L LLT ++A + G +S E + ++ + P+ Sbjct: 76 VDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKP---DIKKINPIE------ 126 Query: 143 GLG-FGSLNAADEFWIPAVSPIMSSLALVVGVGVLWWQVGTNIGSMQFALRGGIVLALAT 201 G S+ + EF + S L +V+ ++W + N+ ++ GI Sbjct: 127 GAKRIFSIKSLVEF-------LKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITP- 178 Query: 202 LVGALLQWLIQLPAL 216 L+G +L+ L+ + + Sbjct: 179 LLGQILRQLMVICTV 193
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 29.0 bits (65), Expect = 0.034 Identities = 21/126 (16%), Positives = 38/126 (30%), Gaps = 10/126 (7%) Query: 156 YRTSDGGTTWKATVSEAAGAVRDLRRSAAGNYVSVSSLGNFFSTLDLGQDVWQNHERVSS 215 D ++ A G + + GN D+ Q + VS Sbjct: 640 TLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSG 699 Query: 216 KRVQSLGY----QPNGELWMV-----ARGAEIRLNDQPGNVDSWGKAMIPITNGYNYLDL 266 + QP + ++ A+ A++ N D G A++P Y + Sbjct: 700 GVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVE-NQTGVRTDWRGYAVLPYATEYRENRV 758 Query: 267 SWDPNG 272 + D N Sbjct: 759 ALDTNT 764
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 96.3 bits (239), Expect = 3e-24 Identities = 62/257 (24%), Positives = 104/257 (40%), Gaps = 17/257 (6%) Query: 459 VVLVTGGGGGIGAAIALAFAKQGAQVVVLDKNGE---AATTTAKECGSSALGLKCDLTNA 515 + +TG GIG A+A A QGA + +D N E ++ K A D+ ++ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 516 SEVHDAFTTIAACFGGLDIVVSNAGAAWSGDIATLPESKLRASFELNLFAHQHVAQAAVR 575 + + + I G +DI+V+ AG G I +L + + A+F +N + +++ + Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 576 LFRAQGNRTTETSKSLGGQLLFNVSKQALNPGPGFGAYGIAKAALLALMKQYALEEGPSS 635 + G ++ S A P AY +KAA + K LE + Sbjct: 130 YMMDRR----------SGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 636 IRCNAINADRIRSGLLDQAMIRERAEARGI--SEANYMGGNLLGAEVRASDVANA--FVA 691 IRCN ++ + + E + I S + G L + SD+A+A F+ Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 692 LALMPRTTGALLTVDGG 708 T L VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 508 bits (1310), Expect = 0.0 Identities = 192/336 (57%), Positives = 239/336 (71%), Gaps = 4/336 (1%) Query: 5 VVVTGAAGFIGAALVQRLLAQGDRVIGIDNLNDYYDPSLKRARLAQVEAASLKASWTFYP 64 +VTGAAGFIG + +RLL G +V+GIDNLNDYYD SLK+ARL + + + F+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLA----QPGFQFHK 58 Query: 65 IALEDGAAIEELFKAEKPEVVVNLAAQAGVRYSLENPAAYIQANLVGFGHILEGCRHHGV 124 I L D + +LF + E V + VRYSLENP AY +NL GF +ILEGCRH+ + Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 125 QHLVYASSSSVYGGNRNLPFHEQQPVNHPVSLYAATKKANELMAHTYSHLYGLPATGLRF 184 QHL+YASSSSVYG NR +PF V+HPVSLYAATKKANELMAHTYSHLYGLPATGLRF Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRF 178 Query: 185 FTVYGPWGRPDMAPMLFAKAILAGEPIKVFNYGKMQRDFTYIDDIVEGLLRCCDKPATAN 244 FTVYGPWGRPDMA F KA+L G+ I V+NYGKM+RDFTYIDDI E ++R D A+ Sbjct: 179 FTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHAD 238 Query: 245 LGFDPRNPDPATAAVPHRLFNIGNSQPIELMHFIEFLENSLGREAVKDFQPMQPGDVMAT 304 + PA + P+R++NIGNS P+ELM +I+ LE++LG EA K+ P+QPGDV+ T Sbjct: 239 TQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVLET 298 Query: 305 AADTSALEAWVDFRPSTPIAEGVECFSQWYRSFYEV 340 +ADT AL + F P T + +GV+ F WYR FY+V Sbjct: 299 SADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYKV 334
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.4 bits (68), Expect = 0.014 Identities = 17/83 (20%), Positives = 34/83 (40%), Gaps = 7/83 (8%) Query: 164 NSLGTLQDRQKYREELVAWLEARSEELD--DDSRKRLYTNPLRILDSKHPAIKELLQDAP 221 ++ + + L A + + +R+ L R LD+ A K+L + Sbjct: 278 ADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSL----RRDLDASREAKKQLEAEHQ 333 Query: 222 TLFEALSVESKARFEEVQVDLEA 244 L E + S+A + ++ DL+A Sbjct: 334 KLEEQNKI-SEASRQSLRRDLDA 355
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 160 bits (406), Expect = 1e-48 Identities = 83/354 (23%), Positives = 150/354 (42%), Gaps = 45/354 (12%) Query: 5 LITGGAGFIGSHTCLVLLEAGHRLVILDNFSNSSAIASKRVAELAGVAAQERMLVLEGDI 64 L+TG AGFIG H LLEAGH++V +DN ++ ++ K+ + AQ + D+ Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQ--ARLELLAQPGFQFHKIDL 61 Query: 65 RNSNDLDRAFNSMENGIAAVVHFAGLKAVHESVQLPLKYWDVNVAGSRCLLEAMQRHNCR 124 + + F V AV S++ P Y D N+ G +LE + + + Sbjct: 62 ADREGMTDLFA--SGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 125 TIVFSSSATLYGYPEQIPIPETTRV-QPINPYGQSKAAVEQLLDDLACSEP---GWRIAR 180 ++++SS+++YG ++P V P++ Y +K A E +A + G Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANEL----MAHTYSHLYGLPATG 175 Query: 181 LRYFNPVGAHSSGCIGEDPKGIPN-NLFPFVSQVAVGRRAELQVFGADWPTPDGSGVRDY 239 LR+F G P G P+ LF F + G+ + V+ G RD+ Sbjct: 176 LRFFTVYG----------PWGRPDMALFKFTKAMLEGKSID--VYN------YGKMKRDF 217 Query: 240 IHVMDLAEGHRAALEVLQREEPQLLT--------------LNLGSGKGHSVLEVVQAFEK 285 ++ D+AE +V+ + Q N+G+ +++ +QA E Sbjct: 218 TYIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALED 277 Query: 286 ASGQPVPYSINQRRAGDAACSVADPRLAAERLGWYTQRSLSDMCRDSWNWQKAN 339 A G ++ + GD + AD + E +G+ + ++ D ++ NW + Sbjct: 278 ALGIEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 31.0 bits (70), Expect = 0.019 Identities = 30/168 (17%), Positives = 50/168 (29%), Gaps = 6/168 (3%) Query: 572 NKGSHQYDRGIYLTLGTNENGTPIINGNSVLGSKDEQPFGDINQLIETSNTIQTELNESK 631 + + R Y T+ +N ING + P + N I + L Sbjct: 352 SNALKHFYRKQYYTMDYTDNYN--INGFVNGQINTKLPLSNKNTNIISKPEKVVNLVNEN 409 Query: 632 ENKNTNKDQSSESNENEDSDQASTNNSSDDSDNTSTDSSTNDSDDTSTNNADDSSANNSG 691 + + + D ST N + NDSD+ NN ++ Sbjct: 410 NISLMKSNIYGDGLKGTTEDFYSTYKIPY---NEEYEYRFNDSDNFPLNNISIEEVDSIP 466 Query: 692 ETSTDTSSNDSGNSSTSSTSSDDTHNQATNTGTGGNR-NNNNNNNNNI 738 E D+ ++ + + T T+T N NN N Sbjct: 467 EIIDINPYKDNSDNLVFTQITSMTEEVTTHTALSINYLQAQITNNENF 514
>AEROLYSIN#Aerolysin signature. Length = 493 Score = 27.7 bits (61), Expect = 0.028 Identities = 12/25 (48%), Positives = 15/25 (60%), Gaps = 1/25 (4%) Query: 73 ASHWVICAPEYNGSIPPAFTSAVAW 97 A+ WVI P YNG I P T++ W Sbjct: 74 ANGWVIMGPGYNGEIKPG-TASNTW 97
>PF06776#Invasion associated locus B Length = 214 Score = 26.4 bits (58), Expect = 0.019 Identities = 13/41 (31%), Positives = 16/41 (39%), Gaps = 5/41 (12%) Query: 29 GDQSSRGAGVTLPTLPDGLESALLQGHTLAVDGTNVVRVPF 69 DQ S+ V P L L G L +D +V R F Sbjct: 122 ADQKSKLMRVVAP-----LGVLLPSGLGLKLDNVDVGRAGF 157
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.9 bits (192), Expect = 4e-17 Identities = 51/244 (20%), Positives = 94/244 (38%), Gaps = 34/244 (13%) Query: 20 GRPRRGVVGGSRYACKLRESIRQAANDPERKPVLISGEPGLEKDNIARLVHFGSADRRLL 79 + +VG S ++ + + ++I+GE G K+ +AR +H R Sbjct: 133 SQDGMPLVGRSAAMQEIYRVLARLM--QTDLTLMITGESGTGKELVARALHDYGKRRNGP 190 Query: 80 LMRFDASNIRGQ--GVELFGREG-------SHELSLLDCLGNGNLLIDCIDLAEPQLQAR 130 + + + I ELFG E + + G L +D I Q R Sbjct: 191 FVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTR 250 Query: 131 LIALATEGHPAFSG---------RILLTAESSLKEL--EGI----------ATQIRVPPL 169 L+ + +G G RI+ LK+ +G+ +R+PPL Sbjct: 251 LLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPL 310 Query: 170 RVRRSDLGDWLRYSLRQRSPSLGWSRPPELPEAIVRRLQSHDFPNNIRELDSVVERALQQ 229 R R D+ D +R+ + Q++ G + + +++H +P N+REL+++V R Sbjct: 311 RDRAEDIPDLVRHFV-QQAEKEG-LDVKRFDQEALELMKAHPWPGNVRELENLVRRLTAL 368 Query: 230 ARSQ 233 Sbjct: 369 YPQD 372
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 28.7 bits (64), Expect = 0.014 Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 8/86 (9%) Query: 102 SAQQLLNQVGLNGLGARRL-DRLSGGQQQRVLLA-----RALMQQTSILLLDEPCSAIDP 155 +A +LLN+ G++GL R+L +L G +Q L RAL+ ++ +L P Sbjct: 12 AALELLNETGIDGLTTRKLAQKL--GIEQPTLYWHVKNKRALLDALAVEILARHHDYSLP 69 Query: 156 PTREHLLTVMRQQAESGQTLLVSSHD 181 E + +R A S + L+ D Sbjct: 70 AAGESWQSFLRNNAMSFRRALLRYRD 95
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 140 bits (354), Expect = 2e-41 Identities = 61/310 (19%), Positives = 125/310 (40%), Gaps = 29/310 (9%) Query: 11 AIHALLVLATVSANPVSAQASQPTVVAIDGVLCDLTRTLVASDAKVVCLIQPGSDPHNYR 70 + A++++A S + + VVA + ++ D+T+ + + ++ G DPH Y Sbjct: 11 FLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYE 70 Query: 71 LKPSDRQALSSASLVLHNGYNL----TPSANKISGSAKVV-----AVAEKAIPTTDHANH 121 P D + S A L+ +NG NL K+ +AK + Sbjct: 71 PLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVDVIYLEGQ 130 Query: 122 DNGHAEHGAHDHDGSDPHVWHDPANSAAMVTVIAERLAPILPATQQSALAARAAEAINVL 181 + E DPH W + N IA++L+ P + E + L Sbjct: 131 NEKGKE---------DPHAWLNLENGIIFAKNIAKQLSAKDPN-NKEFYEKNLKEYTDKL 180 Query: 182 NAVGDWGGKQFATIPENQRVLVSEHKAYSHLTNRYGLRQITMLDSFTT--GGVLRPSSLR 239 + + +F IP ++++V+ A+ + + YG+ + + T G P ++ Sbjct: 181 DKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGT---PEQIK 237 Query: 240 TITAEVEGSGAQTLFPESLPVSKTLRRINRSTGLPVYSSPLFADGLA----PDRSTVGTA 295 T+ ++ + +LF ES + ++ +++ T +P+Y + +F D +A S Sbjct: 238 TLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIY-AQIFTDSIAEQGKEGDSYYSMM 296 Query: 296 TLNICTVVQG 305 N+ + +G Sbjct: 297 KYNLDKIAEG 306
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.4 bits (66), Expect = 0.021 Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 15/129 (11%) Query: 188 SEVLEQSSREFLDLLALLVLGCVIAALVQSWL-PRSWLLAVGSAPTLSIVALMLLAIVVS 246 E L + L ++ +V+ +AAL +SW P S +L V ++A L Sbjct: 864 QERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKND 923 Query: 247 VCSSVDAFLALGFAAQVTPGALLAFLLLGPVVDLKL--------AGLFTVLLRPKAIGIT 298 V V +G + A A L++ DL A L V +R + I +T Sbjct: 924 VYFMVGLLTTIGLS------AKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMT 977 Query: 299 AIVACLGVL 307 ++ LGVL Sbjct: 978 SLAFILGVL 986
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 177 bits (450), Expect = 4e-53 Identities = 98/439 (22%), Positives = 174/439 (39%), Gaps = 80/439 (18%) Query: 27 SHDESVLQQSRFWMRAVTWSLIGTTAFAVGWLAIARTEEIVVAQGKLEPLGDVKEIQIPV 86 +H E + R V + ++G A + + E + A GKL G KEI+ Sbjct: 44 AHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIE 103 Query: 87 GGVARDILIKGGDRVSKGQILIQLDT---------------------------------- 112 + ++I++K G+ V KG +L++L Sbjct: 104 NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELN 163 Query: 113 -------------ETSSEQVNSLEAQLTKKQ--------QQLKLKLEEQQGTLHLSQEQV 151 + SE+ L K+Q Q +L L++++ ++ Sbjct: 164 KLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARI 223 Query: 152 ATTRDNLALEQQILSRFEFLSAQGAYSELQYLQQLNKVRELRGRV--------------- 196 + +E+ L F L + A ++ L+Q NK E + Sbjct: 224 NRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEIL 283 Query: 197 -TKEKLDGARQ--QSILNQEIEQLNSQLAQLKAQLTEAKVTLKYQSLRSPVDGVVFDLKP 253 KE+ Q ++ + ++ Q + L +L + + + +R+PV V LK Sbjct: 284 SAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKV 343 Query: 254 TTPGFVAQSSEPVLKIVPFKN-LEADVEIPSNKIGFVREGMSVDISIDSFPATDFGVLEG 312 T G V ++E ++ IVP + LE + + IGF+ G + I +++FP T +G L G Sbjct: 344 HTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVG 403 Query: 313 KVTSIGSDALPPDQQEQRQEYRFPATIQLDSQQLKLKNGTTLPLQVGMSLTANIKLRSVT 372 KV +I DA+ ++QR F I ++ L +PL GM++TA IK + Sbjct: 404 KVKNINLDAI----EDQRLGLVFNVIISIEENCL-STGNKNIPLSSGMAVTAEIKTGMRS 458 Query: 373 YLQLLLGQFQ-SKTDSLRQ 390 + LL + S T+SLR+ Sbjct: 459 VISYLLSPLEESVTESLRE 477
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.2 bits (68), Expect = 0.046 Identities = 11/48 (22%), Positives = 21/48 (43%) Query: 533 QALTTLLDAAFSVIYVVVMVIYSWLLTLIALAVLPIQVGLTLVGAPLF 580 + + TL +A V V+ + + + TLI +P+ + T F Sbjct: 339 EVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAF 386
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 28.0 bits (62), Expect = 0.040 Identities = 16/70 (22%), Positives = 30/70 (42%), Gaps = 8/70 (11%) Query: 189 VVSMCMFLSPIFYPSSAIPQDLIWLARINPLAQTIEQTRQILIEG--------IAPSGLQ 240 V++ +FLS +P +P AR PL+ +I+ R I++ + + Sbjct: 185 VITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIY 244 Query: 241 IAVQFLISIG 250 I + F +S Sbjct: 245 IVIPFFLSTA 254
>SECA#SecA protein signature. Length = 901 Score = 41.0 bits (96), Expect = 1e-08 Identities = 18/32 (56%), Positives = 22/32 (68%) Query: 1 MPHACLVVSEACNRVRVIRLFDVQQIGGMVLH 32 +P A VV EA RV +R FDVQ +GGMVL+ Sbjct: 64 IPEAFAVVREASKRVFGMRHFDVQLLGGMVLN 95
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 45.9 bits (109), Expect = 9e-08 Identities = 33/129 (25%), Positives = 50/129 (38%), Gaps = 3/129 (2%) Query: 42 LDLADAQACRAAVFQHRPDWVLNAGAYTAVDHAEQEPDLALAVNASAPRALAEGLLETG- 100 +DLAD + + V + AV ++ + P N + + EG Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 101 GRMLQVSTDFVFNGAQGHPYRPNQPRD-PLGVYGATKAAGEEAVEQILGAQGRAVT-LRT 158 +L S+ V+ + P+ + D P+ +Y ATK A E G T LR Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRF 178 Query: 159 SWVYGPVGR 167 VYGP GR Sbjct: 179 FTVYGPWGR 187
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 169 bits (429), Expect = 1e-51 Identities = 83/349 (23%), Positives = 143/349 (40%), Gaps = 38/349 (10%) Query: 12 RVLITGGAGFIGGAVVRRLLEGSQANVFNLDKL--GYASDLTSIRQ----NDRYKHLHVD 65 + L+TG AGFIG V +RLLE V +D L Y L R ++ +D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQ-VVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 66 LADSAATSAAVVTADPDLVMHLAAESHVDRSIDGPKAFIESNVNGTFNLLQAVLSHWEKL 125 LAD + + + V V S++ P A+ +SN+ G N+L+ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGC------- 113 Query: 126 PEERHQHFRFHHI---STDEVFGSLGPIGRFSEITPYD-PRSPYSASKAASDHLVSAWHH 181 +H + H+ S+ V+G + FS D P S Y+A+K A++ + + H Sbjct: 114 -----RHNKIQHLLYASSSSVYGLNRKM-PFSTDDSVDHPVSLYAATKKANELMAHTYSH 167 Query: 182 TYGLPVVLTNCSNNYGPWQFPEKLIPIAILKAVAGEPIPLYGDGTNIRDWLYVEDHVEAL 241 YGLP YGPW P+ + + G+ I +Y G RD+ Y++D EA+ Sbjct: 168 LYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAI 227 Query: 242 LLAATRGGLGESYCVGGAGDHGSPSER---------TNRDVLETICNLMDSLRPYGAPHT 292 + ++ G + + ++++ I L D+L + Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNM 287 Query: 293 RLITRVSDRPGHDRRYAIDAKKITNDLGWKPRHSFEEGLEATVAWYLDN 341 + +PG + D K + +G+ P + ++G++ V WY D Sbjct: 288 -----LPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.039 Identities = 21/118 (17%), Positives = 39/118 (33%), Gaps = 17/118 (14%) Query: 266 PSQIPKLQERLISRFSMGLIADIQSPDLETRMAILQKKAEQERMMLPRDLIQYIAG-RFT 324 P ++P L++R DI PDL +K + ++ ++ + + Sbjct: 304 PLRLPPLRDR---------AEDI--PDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWP 352 Query: 325 SNIRELEGALTRAVAFA-----SITGLPMTVESVAPMLDPNGQGVDVTPQQVIDKVSE 377 N+RELE + R A + + + S P + V E Sbjct: 353 GNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEE 410
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 80.8 bits (199), Expect = 4e-19 Identities = 38/199 (19%), Positives = 66/199 (33%), Gaps = 36/199 (18%) Query: 97 GPPIQRQAGQGSGFITRSDGLIFTNAHVVDGAERVSVTL------------PDGRSYSGK 144 SG + + TN HVVD L P+G + + Sbjct: 94 QVEAPTGTFIASGVVV-GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQ 152 Query: 145 VLGGDPLTDVAVVKV--------VAKKLPVAPLGNSNNIKPGQWAIAIGNPLGLNNT--- 193 + D+A+VK + + + A + N+ + Q G P Sbjct: 153 ITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMW 212 Query: 194 VTAGIISSVDRTNALGGGQRVPYIQTDAAVNPGNSGGPLINASGQVIGINTA-IKVAPGG 252 + G I+ + + +Q D + GNSG P+ N +VIGI+ + G Sbjct: 213 ESKGKITYL----------KGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNG 262 Query: 253 GLSFAVPI-NLAKRIAQQI 270 + + N K+ + I Sbjct: 263 AVFINENVRNFLKQNIEDI 281
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.0 bits (75), Expect = 3e-04 Identities = 17/81 (20%), Positives = 29/81 (35%), Gaps = 14/81 (17%) Query: 99 ATVWDVAIHPIYQGVGLGKHLMDYTLESLKE---MGVKRVTLFADPGVVDFYERQGWTL- 154 A + D+A+ Y+ G+G L+ +E KE G+ T + FY + + + Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIG 149 Query: 155 ----------EPDGHKCAFWY 165 FWY Sbjct: 150 AVDTMLYSNFPTANEIAIFWY 170
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 27.8 bits (62), Expect = 0.029 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 3/70 (4%) Query: 20 RRRLWMVLVLLVPVALAGAIQPFLVG--QAISVLKQESTFPWLSDLPVSSAIRVLVGILL 77 + L++VL+L + I LVG Q ++ L QE T P+ L L+ Sbjct: 9 NKALYLVLILSGWPTIVATIIGLLVGLFQTVTQL-QEQTLPFGIKLLGVCLCLFLLSGWY 67 Query: 78 ISVLLRLGLQ 87 VLL G Q Sbjct: 68 GEVLLSYGRQ 77
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 27.8 bits (61), Expect = 0.020 Identities = 16/53 (30%), Positives = 20/53 (37%), Gaps = 7/53 (13%) Query: 85 EAPSLQRPANWSIRLPNLNMTATTAARPVSARRPSLRPAPPPPPATGPTKAPN 137 EAP+ Q LP ++ A P P RP P P P P P+ Sbjct: 321 EAPNAQP-------LPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPD 366
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 43.1 bits (101), Expect = 2e-06 Identities = 28/123 (22%), Positives = 43/123 (34%), Gaps = 13/123 (10%) Query: 13 IPSPAMSPAATQAAAAKAQPKASAKTAKPQVAKGTAKTKAKKVKATAAKAKTAAKPVSSA 72 +P PA + + K +KT + T T + A AK+ A ++ Sbjct: 1025 VPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNE 1084 Query: 73 AKASSPKAKKAKATPPPTVSKNLDLTADQLLATAATSAPKASAETESSQAAAKATSEADA 132 S + K+ + T +K TA KA ETE +Q K TS+ Sbjct: 1085 VAQSGSETKETQ----TTETKE---TATV------EKEEKAKVETEKTQEVPKVTSQVSP 1131 Query: 133 KAR 135 K Sbjct: 1132 KQE 1134
>PF05043#Transcriptional activator Length = 493 Score = 27.6 bits (61), Expect = 0.036 Identities = 12/48 (25%), Positives = 17/48 (35%), Gaps = 9/48 (18%) Query: 10 RSTPNLLHVLPAFADESELRLNTIVELNSNTINKYELIT---ETGHLK 54 H+L F D+ ++ +E NK LI T HL Sbjct: 285 SYVEKSYHLLSDFIDQISVKYQIEIE------NKDNLIWHLHNTAHLY 326
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 26.3 bits (58), Expect = 0.029 Identities = 8/54 (14%), Positives = 26/54 (48%), Gaps = 5/54 (9%) Query: 15 FQMSEEQLKAFLEKVKADTSLQEKLKAA----ADSDAVLVIA-KDAGFSISADD 63 F ++E+ L+ F+++V +++ ++ + + V A +++ A + Sbjct: 84 FFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGARE 137
>PF04619#Dr-family adhesin Length = 160 Score = 26.0 bits (57), Expect = 0.040 Identities = 24/108 (22%), Positives = 43/108 (39%), Gaps = 1/108 (0%) Query: 15 LAFAGAMLFLTTPSMAFKGIRQIPYPQAEQVTRTAAEAVIVRSGSESCLRGKLTNALLDL 74 LA A + S A G ++T T V V + + RG+LT+A Sbjct: 4 LAIMAAASMVFAVSSAHAGFTPSGTTGTTKLTVTEECQVRVGDLTVAKTRGQLTDAAPIG 63 Query: 75 TMSCSATGRSSSLCKLAAQVSS-QEGEFSLAQMTTTAETLLDLLDTDS 121 ++ A G + L A + ++G+F L + +++ TD+ Sbjct: 64 PVTVQALGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDN 111
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 482 bits (1243), Expect = e-154 Identities = 213/565 (37%), Positives = 338/565 (59%), Gaps = 14/565 (2%) Query: 4 SNSFITRPVLATVCSLLIVIAGLISIPILPVEMLPDIAPPTVKVNSIYTGADAESVEQGV 63 +N FI RP+ A V ++++++AG ++I LPV P IAPP V V++ Y GADA++V+ V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 TSVLEQQINGVENMDYLTSSSSADGVSSIAVAFESGSNSDINQVNVQNRVALAEPQLPEA 123 T V+EQ +NG++N+ Y++S+S + G +I + F+SG++ DI QV VQN++ LA P LP+ Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 124 VRKAGVSVNKASNSILLLYNFVSEDPSNIEYSVETISGLLDLGLTDEVKRVKGVGEVTYF 183 V++ G+SV K+S+S L++ FVS++P + + IS + + D + R+ GVG+V F Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNP---GTTQDDISDYVASNVKDTLSRLNGVGDVQLF 178 Query: 184 GNRKVAFRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGNVGGEPSAEGQIFTFPVQLN 243 G + A R+WLD + L + LT DV+ ++ QN + AG +GG P+ GQ + Sbjct: 179 GAQY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQ 237 Query: 244 GRLVSIGDFENMVVRTTEDGGLVRFSDVGHVVLGGESYSNSATDLQGVPSVSMAVYQLSG 303 R + +F + +R DG +VR DV V LGGE+Y+ A + G P+ + + +G Sbjct: 238 TRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIAR-INGKPAAGLGIKLATG 296 Query: 304 SNALEVSNGVKDVLEEFTAKMPVGMKIEKIYDNTDFINASINGVTNSLRDAIILVVLILF 363 +NAL+ + +K L E P GMK+ YD T F+ SI+ V +L +AI+LV L+++ Sbjct: 297 ANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMY 356 Query: 364 VFLQNWKATLVPGIAIPVALLGTFSLVLWFGFSLNQLTLFGLVLATGLVVDDAITVIEDT 423 +FLQN +ATL+P IA+PV LLGTF+++ FG+S+N LT+FG+VLA GL+VDDAI V+E+ Sbjct: 357 LFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENV 416 Query: 424 S-TKQSLGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATIIF 482 + EA + +M ++ A++ ++VL +VF+P+ FF G+TG+IY+QF+ TI+ Sbjct: 417 ERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVS 476 Query: 483 AIAISTFNALTFSPMLSALLLGREGTAPGRNAYAISG--------AVIGFIYGLLVVGGG 534 A+A+S AL +P L A LL N G +V + + + G Sbjct: 477 AMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGS 536 Query: 535 AALALILTAMAAILGFVLSRLTGRS 559 L++ A+ VL S Sbjct: 537 TGRYLLIYALIVAGMVVLFLRLPSS 561 Score = 438 bits (1128), Expect = e-138 Identities = 191/595 (32%), Positives = 318/595 (53%), Gaps = 12/595 (2%) Query: 533 GGAALALILTAMAAILG-FVLSRLTGRSLR-LPFSVAGAV-IGLFIAGVSSP-LPVVLFA 588 GA + + + A + TG R ++ A+ + + +A + +P L L Sbjct: 439 QGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLK 498 Query: 589 GLGLTLGWYTPWIFSHFNRIYSVFELRYADLLEWVLGRRSLVMGILAVGVLLTGVAFTAI 648 + F FN + Y + + +LG + I A+ V V F + Sbjct: 499 PVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRL 558 Query: 649 PSGFVPIEDQGYAIGVLQAPEGVSTQVTEKINQQVAE-ILRSESD-ITSAAIFSGASFDG 706 PS F+P EDQG + ++Q P G + + T+K+ QV + L++E + S +G SF G Sbjct: 559 PSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSG 618 Query: 707 NSPNKGLFFIGMRNWDERKNRDQSADAIVGRLNQKFFGAIDGARIFVVEPPAIPGYGIGS 766 + N G+ F+ ++ W+ER + SA+A++ R + G I + PAI G + Sbjct: 619 QAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMEL-GKIRDGFVIPFNMPAIVELGTAT 677 Query: 767 GFEFQLLDKSGGAYGLNNFFASAGQIIQQAKANP-MLSSVRTLFSPESPQLRVEVDRDIM 825 GF+F+L+D++G G + + Q++ A +P L SVR ++ Q ++EVD++ Sbjct: 678 GFDFELIDQAG--LGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKA 735 Query: 826 ASLDVDFSSAMRVFSANFAGAYVNDTFQEGKVRRVYVQADELGRSAPEKLSSIYVKNRVG 885 +L V S + S G YVND G+V+++YVQAD R PE + +YV++ G Sbjct: 736 QALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANG 795 Query: 886 EQIQLSEFLTVEPSVGPSVISHFNLYRSIKIEGSPAAGKSSGQAINGMKELFAAQNLKSL 945 E + S F T G + +N S++I+G A G SSG A+ M+ L A++ + Sbjct: 796 EMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENL-ASKLPAGI 854 Query: 946 GFDWTGISREEVKAGALAVVIFALGILVVYLVLAAQYESYTDPLIILMTVPTAMLGALFF 1005 G+DWTG+S +E +G A + A+ +VV+L LAA YES++ P+ +++ VP ++G L Sbjct: 855 GYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLA 914 Query: 1006 LALRGEVLNIYAQVGLVMLIGLAAKNGILIVDLANQRM-AEGVSALEAARQAAKSRLRPI 1064 L + ++Y VGL+ IGL+AKN ILIV+ A M EG +EA A + RLRPI Sbjct: 915 ATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPI 974 Query: 1065 IMTAISSLFGFMPLVLASGAGARSQASLGTVVFGGLLVATFLSLFVVPVFYVAVK 1119 +MT+++ + G +PL +++GAG+ +Q ++G V GG++ AT L++F VPVF+V ++ Sbjct: 975 LMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIR 1029 Score = 88.7 bits (220), Expect = 7e-20 Identities = 61/316 (19%), Positives = 122/316 (38%), Gaps = 16/316 (5%) Query: 190 FRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGNVGGEPSAEGQIFTFPVQLNGRLV-S 248 F+L +D EK + G++ +D+ I + G + G++ VQ + + Sbjct: 726 FKLEVDQEKAQALGVSLSDINQTISTAL----GGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 249 IGDFENMVVRTTEDGGLVRFSDVGHVVLGGESYSNSATDLQGVPSVSMAVYQLSGSNALE 308 D + + VR+ +G +V FS S G+PS+ + G A Sbjct: 782 PEDVDKLYVRS-ANGEMVPFSAFTTSHW--VYGSPRLERYNGLPSME-----IQGEAAPG 833 Query: 309 VSNG-VKDVLEEFTAKMPVGMKIEKIYDNTDFINASINGVTNSLRDAIILVVLILFVFLQ 367 S+G ++E +K+P G+ + + S N + + ++V L L + Sbjct: 834 TSSGDAMALMENLASKLPAGIGYD-WTGMSYQERLSGNQAPALVAISFVVVFLCLAALYE 892 Query: 368 NWKATLVPGIAIPVALLGTFSLVLWFGFSLNQLTLFGLVLATGLVVDDAITVIEDT-STK 426 +W + + +P+ ++G F + + GL+ GL +AI ++E Sbjct: 893 SWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLM 952 Query: 427 QSLGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATIIFAIAI 486 + G +EA + ++ TSL LP+ GA ++ + Sbjct: 953 EKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVS 1012 Query: 487 STFNALTFSPMLSALL 502 +T A+ F P+ ++ Sbjct: 1013 ATLLAIFFVPVFFVVI 1028 Score = 83.0 bits (205), Expect = 4e-18 Identities = 56/315 (17%), Positives = 119/315 (37%), Gaps = 20/315 (6%) Query: 815 QLRVEVDRDIMASLDV---DFSSAMRVFSANFAGAYVNDTFQEGKVRRVYVQADELGRSA 871 +R+ +D D++ + D + ++V + A + T + + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 872 PEKLSSIYVK-NRVGEQIQLSEFLTVEPSVGP-SVISHFNLYRSIKIEGSPAAGKSSGQA 929 PE+ + ++ N G ++L + VE +VI+ N + + A G ++ Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 930 INGMKELFAAQNLK-------SLGFDWTGISREEVKAGALAVVIFAL--GILVVYLVLAA 980 +K A +D T + + V+ L I++V+LV+ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHE-----VVKTLFEAIMLVFLVMYL 357 Query: 981 QYESYTDPLIILMTVPTAMLGALFFLALRGEVLNIYAQVGLVMLIGLAAKNGILIVDLAN 1040 ++ LI + VP +LG LA G +N G+V+ IGL + I++V+ Sbjct: 358 FLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVE 417 Query: 1041 QRMAE-GVSALEAARQAAKSRLRPIIMTAISSLFGFMPLVLASGAGARSQASLGTVVFGG 1099 + M E + EA ++ ++ A+ F+P+ G+ + Sbjct: 418 RVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSA 477 Query: 1100 LLVATFLSLFVVPVF 1114 + ++ ++L + P Sbjct: 478 MALSVLVALILTPAL 492
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.4 bits (97), Expect = 4e-06 Identities = 18/122 (14%), Positives = 41/122 (33%), Gaps = 4/122 (3%) Query: 103 DQAQIRAELADFKAQEQKNKLNWQRYEFLVPQGAASALDRDEYKAQYIASREKVKATEAT 162 + +++L +++ K +Q L L + ++ E Sbjct: 267 ELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLR--QTTDNIGLLTLELAKNEER 324 Query: 163 LAYSNLRSPISGIVADVDVK-VGDVIRSGDPFTKLI-RNNRLFARVEVPATFSDRIKIGL 220 S +R+P+S V + V G V+ + + ++ ++ L V I +G Sbjct: 325 QQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQ 384 Query: 221 PV 222 Sbjct: 385 NA 386 Score = 39.4 bits (92), Expect = 2e-05 Identities = 14/125 (11%), Positives = 42/125 (33%), Gaps = 19/125 (15%) Query: 74 LAAQASGRIIELKIDQGDQVQPGQMLVVLDQAQIRAELADFKAQEQKNKLNWQRYE---- 129 + + + E+ + +G+ V+ G +L+ L A+ ++ + +L RY+ Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 130 -----------FLVPQGAASALDRDEYKAQYIA----SREKVKATEATLAYSNLRSPISG 174 + + + + + S + + + L R+ Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 175 IVADV 179 ++A + Sbjct: 219 VLARI 223
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 39.8 bits (93), Expect = 4e-05 Identities = 50/264 (18%), Positives = 92/264 (34%), Gaps = 45/264 (17%) Query: 1 MDQNLFTYQGDQELKRHAPLADRLRPRTLEEFVGQGSILAEG-RLLRRAIAADRVGNLLL 59 + + + + P + VG+ + + E R+L R + D L++ Sbjct: 108 LTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDL--TLMI 165 Query: 60 HGPPGVGKTTLARIIAGHT-RAN--FSSLNAVLAGVKELRQE-------------VDAAK 103 G G GK +AR + + R N F ++N A ++L + + Sbjct: 166 TGESGTGKELVARALHDYGKRRNGPFVAINMA-AIPRDLIESELFGHEKGAFTGAQTRST 224 Query: 104 QRLERHGLRTILFIDEVHRFNSAQQDALLPWVENGTVT-------------LIGATTENP 150 R E+ T LF+DE+ Q LL ++ G T ++ AT ++ Sbjct: 225 GRFEQAEGGT-LFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDL 283 Query: 151 YFEVNKALVSRSRLFRLQALE---------NADLHRLLKHALQDCERGYGDRQVMLSTAA 201 +N+ L +RL + D+ L++H +Q E+ G A Sbjct: 284 KQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEK-EGLDVKRFDQEA 342 Query: 202 ANHLVNVA-NGDARSLLNALELAV 224 + G+ R L N + Sbjct: 343 LELMKAHPWPGNVRELENLVRRLT 366
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 28.1 bits (62), Expect = 0.024 Identities = 23/109 (21%), Positives = 38/109 (34%), Gaps = 5/109 (4%) Query: 24 PISPEEEQWAGRLSARRSRQFRQSRGYVRDALADLWQVSALEIPLQAPPGKPPELANGWG 83 + +R + R AL ++ + + + P P L Sbjct: 30 LLWLPHHDRLRSAGRKRKAEHLAGRIAAVHALREVGVRTVPGMGDKRQPLWPDGLFG--- 86 Query: 84 YISFSHCQDALLVGWSPQRVGVDLERSDRPIAAELLARRYFCADDQSAL 132 S SHC L S QR+G+D+E+ A LA +D++ L Sbjct: 87 --SISHCATTALAVISRQRIGIDIEKIMSQHTATELAPSIIDSDERQIL 133