>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 113 bits (285), Expect = 2e-32 Identities = 74/259 (28%), Positives = 120/259 (46%), Gaps = 15/259 (5%) Query: 41 ADKLTDKKAFVTGGDSGIGRAAAIAYAKEGADV-AINYHPDEQKDAEDVKRVIETVGRKC 99 A + K AF+TG GIG A A A +GA + A++Y+P++ E V ++ R Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL---EKVVSSLKAEARHA 59 Query: 100 VLLPGDLRESTFAREVAIKAYEALGGLDILVLNAGMQQFEYDIEQLDEQQVRDTFEVNVF 159 P D+R+S E+ + +G +DILV AG+ + I L +++ TF VN Sbjct: 60 EAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGL-IHSLSDEEWEATFSVNST 118 Query: 160 SNIFTIQSVLKHL--QPGASIIITSSIQGVKPSAHLVDYAMTKSCNISMTKSLAAQLGPK 217 +SV K++ + SI+ S P + YA +K+ + TK L +L Sbjct: 119 GVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY 178 Query: 218 GIRVNSVAPGPVWTPLQISGGQPQD--------NIPEFGKKEPLGRAGQPVELADVYVLL 269 IR N V+PG T +Q S ++ ++ F PL + +P ++AD + L Sbjct: 179 NIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFL 238 Query: 270 ASDNASYITGQVYGITGGS 288 S A +IT + GG+ Sbjct: 239 VSGQAGHITMHNLCVDGGA 257
>adhesinb#Adhesin B signature. Length = 310 Score = 326 bits (837), Expect = e-114 Identities = 138/305 (45%), Positives = 212/305 (69%), Gaps = 7/305 (2%) Query: 8 KIIVFFALATLLLSACSQDKN-----EGKIKIVTSNSIIYDMTKSIAGDHADVINIVPIG 62 + +V LA + L+ACS K+ K+ +V +NSII D+TK+IAGD ++ +IVP+G Sbjct: 5 RFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSIVPVG 64 Query: 63 HDPHDYEVKPKDIKAITDADVVLFNGLNLETSSG-WFQKALQQGDKKLEDDNVIAVSDGV 121 DPH+YE P+D+K + AD++ +NG+NLET WF K ++ KK E+ + AVS+GV Sbjct: 65 QDPHEYEPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENA-KKKENKDYYAVSEGV 123 Query: 122 KKIFLNERHDDNAIDPHAWLSIDNGILYSKNIARALERADKKHSKAYHHNMEQYTKRLTA 181 I+L + + DPHAWL+++NGI+Y++NIA+ L D + + Y N++ Y ++L+A Sbjct: 124 DVIYLEGQSEKGKEDPHAWLNLENGIIYAQNIAKRLSEKDPANKETYEKNLKAYVEKLSA 183 Query: 182 LSAQYKDKFNDIPKSKRHLITSEGAFKYFSRDYELSHAYIWEINTEKQGTPEQLKQAINF 241 L + K+KFN+IP K+ ++TSEG FKYFS+ Y + AYIWEINTE++GTP+Q+K + Sbjct: 184 LDKEAKEKFNNIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEK 243 Query: 242 VKNHDVKSLFVETSVDKRSMQSLSEMTKTPIYGEVYTDSIGQKGTDGDSYYKMMEHNIKT 301 ++ V SLFVE+SVD R M+++S+ T PIY +++TDS+ +KG +GDSYY MM++N++ Sbjct: 244 LRKTKVPSLFVESSVDDRPMKTVSKDTNIPIYAKIFTDSVAEKGEEGDSYYSMMKYNLEK 303 Query: 302 IHNGL 306 I GL Sbjct: 304 IAEGL 308
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 60/345 (17%), Positives = 120/345 (34%), Gaps = 53/345 (15%) Query: 62 SIAALMLIILSPIYGIYIDRTNHKKKWVIIFTLIVFLCTFSMGYIYKHPLEGSFLDVPVT 121 ++ ALM +P+ G DR ++ V++ +L +++ + Sbjct: 50 ALYALMQFACAPVLGALSDRFG--RRPVLLVSLAGAAVDYAI------------MATAPF 95 Query: 122 FLVIIILFTIAKFTYNSSLVFYDAMMPSLTSKENHSVISGYGVALGYMGTLFGVISIMTF 181 V+ I +A T + V + E G+M FG + Sbjct: 96 LWVLYIGRIVAGITGATGAVAGAYIADITDGDERAR-------HFGFMSACFGFGMVAGP 148 Query: 182 VGTKDAGET------FIPTALMFLVFSLPIFIFGKDGKRQKEVHHTSLKSGYKEVMETFK 235 V G F AL L F F+ + K ++ L+ + +F+ Sbjct: 149 VLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGER----RPLRREALNPLASFR 204 Query: 236 LAKSKPAIYIFLIVYFFLNDALATSISMMQPYATTVVGFTSQQF----IVIFMAATVFSV 291 A+ + + V+F + + Q A V F +F I ++ F + Sbjct: 205 WARGMTVVAALMAVFFIM-------QLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGI 257 Query: 292 VGAF----VFGYIAKHIGSLKALHYVGLVLMIALILASLPLPKEVFYICAVLF---GVAM 344 + + + G +A +G +AL + IL + + + VL G+ M Sbjct: 258 LHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM 317 Query: 345 GSIWVISRTLIIELAPEEHIGQFFGLFSMSGKLSAVIGPFIYGTI 389 ++ + ++ EE GQ G + L++++GP ++ I Sbjct: 318 PAL----QAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAI 358
>PF06580#Sensor histidine kinase Length = 349 Score = 210 bits (536), Expect = 5e-65 Identities = 64/215 (29%), Positives = 112/215 (52%), Gaps = 12/215 (5%) Query: 362 QIELGEIETQSKLLKDAEIKSLQAQVNPHFFFNAMNTISALIRVDSERARELLLNLSNFF 421 Q E+ + + + + ++A++ +L+AQ+NPHF FNA+N I ALI D +ARE+L +LS Sbjct: 146 QAEIDQWK-MASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELM 204 Query: 422 RSNLQGAKSTSITIEKEIQQVEAYLALEQARFPERFNIHFDIDEALKYAKVPPFIIQILV 481 R +L+ + + +++ E+ V++YL L +F +R I+ A+ +VPP ++Q LV Sbjct: 205 RYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLV 264 Query: 482 ENAIKHAFHNRKSNNDVYVKVKEGQQTIEISVEDNGFGIPEEKRAHIGHNEVTSTSGTGS 541 EN IKH + +K + T+ + VE+ G + + TG+ Sbjct: 265 ENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK-----------ESTGT 313 Query: 542 ALENLNKRLIGLYNSNAQLNFTTSDSGTKFYTSIP 576 L+N+ +RL LY + AQ+ + IP Sbjct: 314 GLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 5e-18 Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 4/116 (3%) Query: 2 RILIVDDEPLARNELRYLLNNIDNTLVVDEADSVEETLTSLLSETYELLFLDINLIDESG 61 IL+ DD+ R L L+ V + + + +L+ D+ + DE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD--VRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 LELAEKINKMKHPPKIVFATAHDSF--AVKAFELNALDYILKPFEQKRIEAALNKA 115 +L +I K + ++ +A ++F A+KA E A DY+ KPF+ + + +A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 29.0 bits (65), Expect = 0.032 Identities = 25/128 (19%), Positives = 53/128 (41%), Gaps = 22/128 (17%) Query: 232 DIMSYFLFAISAFIIGIFLYVITIQKEPIFGLLKAQGISNGF------LAKSLLIQTLIL 285 +++S L + ++ + L + L+ A+ F + ++L++ L Sbjct: 28 EVVSTALIVALSAML-MGLSDYYFEHFSKLMLIPAEQSYLPFSQALSYVVDNVLLEFFYL 86 Query: 286 SLIAVLIALVLTIATAMVIPDIV----PIKFEWDKIAVF-GLTIMITAIIGGLFSIRSIR 340 + +A ++ IA+ +V + IK + KI G + FSI+S+ Sbjct: 87 CFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKINPIEGAKRI--------FSIKSL- 137 Query: 341 KVDPLKTI 348 V+ LK+I Sbjct: 138 -VEFLKSI 144
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 39.5 bits (92), Expect = 4e-05 Identities = 38/161 (23%), Positives = 63/161 (39%), Gaps = 20/161 (12%) Query: 783 LIGRFSLRELYLGRMILFLLLSVAQSTIVVLGNLFILDAYAKHPVYNVLFAI----LVGL 838 L + L ++ LG M + + + + Y ++L+A+ L GL Sbjct: 104 LYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAAL--GYT--QWLSLLYALPVIALTGL 159 Query: 839 AF--TIMVYTLVSLLGNIGKAIAIIIMVLQIAG----GGGTFPIQVTPKFFQAIHPFLPF 892 AF MV T ++ I L I G FP+ P FQ FLP Sbjct: 160 AFASLGMVVTALAP----SYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARFLPL 215 Query: 893 TYAVDLLREAV-GGIVPEIAFSKLGMLYLIAALTFAFGLAL 932 ++++DL+R + G V ++ +G L + + F AL Sbjct: 216 SHSIDLIRPIMLGHPVVDVCQ-HVGALCIYIVIPFFLSTAL 255
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 51.1 bits (122), Expect = 1e-09 Identities = 49/268 (18%), Positives = 104/268 (38%), Gaps = 26/268 (9%) Query: 48 PKRIVVMGASYVGNLIDLGVTPVG-ADQYAFQSDILKPKLK----GVEQLNPGDVEKVAK 102 P RIV + V L+ LG+ P G AD ++ + +P L V ++E + + Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTE 94 Query: 103 LKPDLII-SFDTDKDNKKYEKIAPTIPFTYTKHGYLEVHEL------LGKIVGKEKEAKA 155 +KP ++ S + +IAP F ++ G + + ++ + A+ Sbjct: 95 MKPSFMVWSAGYGPSPEMLARIAPGRGFNFSD-GKQPLAMARKSLTEMADLLNLQSAAET 153 Query: 156 FVDKWNKETKK-DGKEIKKHLGEDKTYSIFQFFQ-KEIYVYGDNWGRGSEIIYQAFDLKM 213 + ++ + + +K+ + + + + V+G N EI+ + + Sbjct: 154 HLAQYEDFIRSMKPRFVKRGA---RPLLLTTLIDPRHMLVFGPN-SLFQEILDE---YGI 206 Query: 214 QDKIVKDVKPTGWKKVSSESLSSYA-GDIVLVSSDAGSATNTVTESNLWKNMDAVKNNRL 272 + + G VS + L++Y D++ D + + + LW+ M V+ R Sbjct: 207 PNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRF 266 Query: 273 VEYDAEDFWF-NDPISLEHQRKVLKDKL 299 WF +S H +VL + + Sbjct: 267 --QRVPAVWFYGATLSAMHFVRVLDNAI 292
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 3e-14 Identities = 27/120 (22%), Positives = 54/120 (45%), Gaps = 3/120 (2%) Query: 2 KIVIADDHAVVRTGFSMILNYQDNMEVVATAADGMEAFQMVSQYKPDVLIMDLSMPPGES 61 I++ADD A +RT + L+ V ++ ++ ++ D+++ D+ MP E+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP-DEN 61 Query: 62 GLIATGKIKEAFPETKILILTMYDDEEYLFHVLKNGANGYILKNAPDEELIKAVRTVYQE 121 +IK+A P+ +L+++ + + GA Y+ K ELI + E Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.8 bits (93), Expect = 1e-05 Identities = 61/354 (17%), Positives = 125/354 (35%), Gaps = 39/354 (11%) Query: 21 FMAWTIIAPLMPFMSQEFTIPESQKA---IILAIPVILGSVLRIPLGYYANLIGARKVFL 77 + +I P++P + ++ A I+LA+ ++ LG ++ G R V L Sbjct: 18 AVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLL 77 Query: 78 FSFIFLLIPVFLLSLAQSTTMLMVAGLFLGVGGAIFSVGVTSVPKYFPKEKH----GLAN 133 S + +++ A +L + + G+ GA +V + ++ G + Sbjct: 78 VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMS 137 Query: 134 GIYGMGNIGTAVSAFAAPPLANAIGWSNTVKSYLVVMALFALLNFLLG----DKDEPKVK 189 +G G A P+ + + + A LNFL G + + Sbjct: 138 ACFGFG--------MVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGER 189 Query: 190 QPLMDQIKGVLPEYKLYL----LSFWYFITFGSFVAFGLFLPNFLV---NNFGLDKVDAG 242 +PL + L ++ ++ + F + + +++ + F D G Sbjct: 190 RPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIG 249 Query: 243 VRTGTFIAIATLLRP-IGGVLGDKLRAMDVLKVVFVGLIIGAAMLSINHQIFFFTAGCLI 301 + F + +L + I G + +L L + + G +L+ F T G + Sbjct: 250 ISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLA------FATRGWMA 303 Query: 302 ISACAGLGNGLIFKLA-PTYYSKQA-----GIVNGIVSMMGGLGGFFPPLVIAA 349 L +G I A S+Q G + G ++ + L PL+ A Sbjct: 304 FPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 50.0 bits (119), Expect = 1e-08 Identities = 36/178 (20%), Positives = 65/178 (36%), Gaps = 17/178 (9%) Query: 369 GTGFILKNVGIVSNYHVFEFIIEELEKGKKPICTDKYFINLYFGINCSKKVKAKVLNYDK 428 +G ++ +++N HV + G ++ Y Sbjct: 104 ASGVVVGKDTLLTNKHVVDA-----THGDPHALKAFPSAINQDNYPNGGFTAEQITKYSG 158 Query: 429 DKDLVILQPKDLNILE-LGFELEEGTIENNS------KVTLLGYPSYNEGDRIKEEQGKL 481 + DL I++ + +G ++ T+ NN+ +T+ GYP + E +GK+ Sbjct: 159 EGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKI 218 Query: 482 LRKINDKKDFEKFEISSVIHAGNSGGPVLNNKGKVLGVATEGRGNDINKVVPITNVLS 539 E + GNSG PV N K +V+G+ G N+ N V I + Sbjct: 219 TYLKG-----EAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENVR 271
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 31.0 bits (70), Expect = 0.002 Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 5/50 (10%) Query: 4 KDQRLNQIIELVESSGKMSVNDLSDML-----NVTKETIRRDLSELEADK 48 K QR +I E++ ++ + ++L D+L NVT+ T+ RD+ EL K Sbjct: 3 KGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVK 52
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.022 Identities = 10/20 (50%), Positives = 13/20 (65%) Query: 33 TLLGPSGCGKSTLLRSIAGL 52 L G G GKSTL+ ++ GL Sbjct: 600 VLEGTGGIGKSTLINTLVGL 619
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 32.9 bits (75), Expect = 0.003 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 11/102 (10%) Query: 57 GGVVFAHIGDKVGRKKTLVMTLTLMGIATVVIGLIPNYETIGIAAPLLLLLCRLVQGLGI 116 G V+ + D++G K+ L+ + + +V+ + ++ ++ I A R +QG G Sbjct: 65 GTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMA-------RFIQGAGA 117 Query: 117 GGEWGGSLLLATEYAPPERR----GFFGSVPQMGVTIGMVLG 154 +++ Y P E R G GS+ MG +G +G Sbjct: 118 AAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIG 159
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 31.2 bits (71), Expect = 0.005 Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 2/38 (5%) Query: 6 DVAKEAGVSVATVSRAMNSSGYVHEDTLKKIN-RAIET 42 VA E V V + +N SG+V EDT+ I R I Sbjct: 236 SVADEYDVQVMIHTDTLNESGFV-EDTIAAIKGRTIHA 272
>PF05272#Virulence-associated E family protein Length = 892 Score = 35.0 bits (80), Expect = 5e-04 Identities = 13/56 (23%), Positives = 19/56 (33%), Gaps = 9/56 (16%) Query: 33 IVFVGPSGCGKSTTLRMIAGLEDITSGEFTIDGARMNDVAPKNRDIAMVFQNYALY 88 +V G G GKST + + GL+ + F I +D Y Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDI---------GTGKDSYEQIAGIVAY 645
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 120 bits (303), Expect = 7e-32 Identities = 79/401 (19%), Positives = 166/401 (41%), Gaps = 16/401 (3%) Query: 15 AFFTFLNETLLNIALTKIMTVFHVDAPTVQWLATGFMLVMGVLMPLSATIIQWFTTRQLF 74 +FF+ LNE +LN++L I F+ + W+ T FML + + + ++L Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 75 IGLMSIFLIGTLVAGCAVN-FPMLLAGRMIQAAGTGLLIPVIMNAMLLLFPPYERGKVMG 133 + + I G+++ + F +L+ R IQ AG ++M + P RGK G Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFG 142 Query: 134 NFGLVMMFAPAIGPTLSGVIVDTLGWRWLFFAVVPFVVFSIGFAFKYLDNVGEVTKPKID 193 G ++ +GP + G+I + W +L ++P + L K D Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLMKLLKKEVRIKGHFD 200 Query: 194 IFSVVLSTIGVAGIIYGFSSVGNIEGGFSNKAVFLPIVIGVISLIIFIYRQNHLTSPLLD 253 I ++L ++G+ + F+ +++ V+S +IF+ +T P +D Sbjct: 201 IKGIILMSVGIVFFML-----------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVD 249 Query: 254 MSVFKYSNYSKGMFIFVVVVMAMFASEIVMPMYLQGPMGFSAKVAG-MILLPGALLNGAM 312 + K + G+ ++ + ++P ++ S G +I+ PG + Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 313 SPVMGRIFDKIGPRKMIIPGMFVLTLVMIFYSTIHPGIPLYIFIIVYMVLMVSISMIMMP 372 + G + D+ GP ++ G+ L++ + S + ++ II+ VL +S Sbjct: 310 GYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFTKTV 368 Query: 373 SHTNAINQLPKHLYPHGTAIGNMIQPIAGAMGISVFVSIMT 413 T + L + G ++ N ++ GI++ +++ Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.8 bits (67), Expect = 0.014 Identities = 10/24 (41%), Positives = 15/24 (62%) Query: 4 KVLLTGATGYIGKYISSQLTAQYD 27 K L+TGA G+IG ++S +L Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGH 25
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 40.3 bits (94), Expect = 4e-08 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 4/77 (5%) Query: 1 MNTLLTVLLIIDCFVLITVVLLQEGKSSGLSGAISGGAE-TLFGKQKQRGVELILNRITI 59 M L V+ +I L+ +++LQ+GK + + + GA TLFG G + R+T Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG---SSGSGNFMTRMTA 57 Query: 60 VASVLLFLITIAIGYFN 76 + + L F+I++ +G N Sbjct: 58 LLATLFFIISLVLGNIN 74
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 50.1 bits (119), Expect = 9e-08 Identities = 47/374 (12%), Positives = 107/374 (28%), Gaps = 55/374 (14%) Query: 3 KNNRYSIRKFSVGTGSVIIGAMLYLSTPNIVNAEESNALKEESQSTETTTNTDSNKNIET 62 N YS+RK GT SV + A+ L +VN E +A+ SQ+ + E Sbjct: 6 TNRHYSLRKLKTGTASVAV-ALTVLGAGLVVNTNEVSAVATRSQTDTLEKVQERADKFEI 64 Query: 63 SNETEVPNSVEIPT-----EESTENLPTE------EKTNDSTETAEDSTTEENTSDSNAS 111 N T + ++ ++ + L E + + +E ++ + A Sbjct: 65 ENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKAD 124 Query: 112 GD--NTTAEPKEQS-DFTIEQIDNQTVNSEDAINPIRINVEGSENNTNEVRGLPDGLTYD 168 + A + I+ ++ + + +EG+ N + Sbjct: 125 LEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTA----------- 173 Query: 169 SNTDTISGTPNTPGNYMITVTSKNDSGVQKESTFTINVEEAEKPSTEEPQTNDDSKSTEE 228 + K + + + S + Sbjct: 174 -----------------DSAKIKTLEAEKAALE-----ARQAELEKALEGAMNFSTADSA 211 Query: 229 DTTEVPTSDEQKSDGNSKSE---DPKEDKSDTTEEPKSTEEDTTEEPKTDDK--KSSEDS 283 + + + E + + S T E + + + + Sbjct: 212 KIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEG 271 Query: 284 KEADADQLKNPSEEQKSDKDSIK-EQPKADDKNSSKEDAKTDENSTNEDSNENKKDT-TE 341 + + +++K +++ E+ + ++ + + S E KK E Sbjct: 272 AMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAE 331 Query: 342 KPKSTEEDTIEEPS 355 K E++ I E S Sbjct: 332 HQKLEEQNKISEAS 345
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 29.3 bits (65), Expect = 0.007 Identities = 15/54 (27%), Positives = 29/54 (53%) Query: 96 VKHFGAEVVIAANTSQQDDTKRAESEVPVQLEKQTQVEKQQQNEQEEPTEHKDK 149 +F V A NT D+ K+A+ ++ L K+ +EK+ + + E + +K+K Sbjct: 588 TLNFNKAVADAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNK 641
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 38.2 bits (89), Expect = 5e-05 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 20/95 (21%) Query: 16 LVSKDIRIEDGKIVEMGEKLNVY-----------NSEIIELDGKFVSQGFVDVHVHLREP 64 +V DI ++DG+I +G+ N +E+I +GK V+ G +D H+H P Sbjct: 83 IVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFICP 142 Query: 65 GGEHKETIESGTRAAARGGF--------TTVCPMP 91 + +E + SG GG TT P P Sbjct: 143 -QQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGP 176
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 27.1 bits (60), Expect = 0.022 Identities = 20/94 (21%), Positives = 33/94 (35%), Gaps = 21/94 (22%) Query: 7 NTDELTFIESYYHQNLSVKEIAKRLKRSRQTIYNVINALKTGITALEYYQEYK------- 59 L + +Y + + + R+ I + AL + IT L YY Sbjct: 124 RKVTLPYSGNY-------ERLQIAAGKIRENIPLGLPALDSAITTLFYYNANSAASALMV 176 Query: 60 --QRKSNCGRYRIVLPENQSAYIREKVADGWTPD 91 Q S RY+ + E Q I ++V + P Sbjct: 177 LIQSTSEAARYKFI--EQQ---IGKRVDKTFLPS 205
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.5 bits (79), Expect = 9e-05 Identities = 24/122 (19%), Positives = 46/122 (37%), Gaps = 2/122 (1%) Query: 18 NNEYSIMSYWFEEPYESLTELQYLFDKHLLDESERRFIVEDENQVVGIVELVEINYIHRN 77 N ++ F +PY E + ++ +E + F+ EN +G +++ N+ Sbjct: 32 NGVWTYTEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRS-NWNGYA 90 Query: 78 CEIQIIIKPEFSGKGYAKFAFEKAISYAFDILNMHKIYLYVDADNKKAIHIYESQGFKTE 137 I + ++ KG KAI +A + + + L N A H Y F Sbjct: 91 LIEDIAVAKDYRKKGVGTALLHKAIEWAKEN-HFCGLMLETQDINISACHFYAKHHFIIG 149 Query: 138 GL 139 + Sbjct: 150 AV 151
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 30.5 bits (68), Expect = 0.009 Identities = 33/175 (18%), Positives = 64/175 (36%), Gaps = 7/175 (4%) Query: 107 YQNNDLEKRHRKDSEKTVKEHRKDSEKTQKKTNNNVNKDNNVNNDNKVISSSNNDDFRTV 166 Y +D+++ H+ + KT KE KDS KT + + ++ D V Sbjct: 38 YTESDIKRNHKTEKNKTEKEKFKDSINNLVKTEFTNETLDKIQQTQDLLKKIPKD----V 93 Query: 167 VSMYQE---NIELNPAPVTFQKIQQDFSDYGKDIMIYAIKKSALKNNHNYSFINYLLNDW 223 + +Y E I + K QD S+ K+ M +K + + Sbjct: 94 LEIYSELGGEIYFTDIDLVEHKELQDLSEEEKNSMNSRGEKVPFASRFVFEKKRETPKLI 153 Query: 224 KKKQLTTVDEIKQSEHNFEFKKQATYSKQNQQKEITPSWINQENTQKQDIDEEEL 278 + ++ + E +E K + ++ K + P ++N + D D +L Sbjct: 154 INIKDYAINSEQSKEVYYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSDSSDL 208
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 36.3 bits (83), Expect = 7e-04 Identities = 58/235 (24%), Positives = 93/235 (39%), Gaps = 23/235 (9%) Query: 787 GMTATKTEEATGRMANATNINTAKMASDVTSNSALMTSGFDVNMNRMSMINDSQWAMING 846 G T T E + + +S + + T+ F + M+ SQ A Sbjct: 901 GSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTL--MAGYGSSQTAREQS 958 Query: 847 TATSQSGAMQAAVLGSV---GGMSAQTTG----LLAGMSGSAQAEFASLYSAGSGQASSL 899 + T+ G+ A S G S QT G L AG + AE +S +AG G ++ Sbjct: 959 SLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEHSSTLTAGYGSTATA 1018 Query: 900 NADVLSSLGGMSSQGVGDIASMTSGINSEFQNMSSTSSSATSNMSSNVQSNMNSMRSSFT 959 AD G SS G + +T+G S +S S T+ S++ S RSS T Sbjct: 1019 GADSSLIAGYGSSLTSGIRSFLTAGYGSTL--ISGLRSVLTAGYGSSLIS---GRRSSLT 1073 Query: 960 SGASGIAQAWASAMQRITSITSSGMSAVRSASVSGMQAVVSAFRSGGQQAVSVTT 1014 +G +I S SS ++ S ++G ++++ A + Q A +T Sbjct: 1074 AGYGS---------NQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGYRST 1119 Score = 32.4 bits (73), Expect = 0.012 Identities = 59/262 (22%), Positives = 97/262 (37%), Gaps = 22/262 (8%) Query: 801 ANATNINTAKMASDVTSNSALMTSGFDVNMNRMSMINDSQWAMINGTATSQSGAMQAAVL 860 T + + DVTS NR + D A I +T + ++ A Sbjct: 113 VACTEMQAGPGSPDVTSEVK--------VGNRSLPVTDDIDATIESGSTQPTQTIEIATY 164 Query: 861 GSVGGMSAQTTGLLAGMSGSAQAEFASLYSAGSGQASSLNADVLSSLGGMSSQGVGDIAS 920 GS + Q+ L+AG + A +S AG G + AD G S+Q G+ +S Sbjct: 165 GSTLSGTHQSQ-LIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESS 223 Query: 921 MTSGINSEFQNM----------SSTSSSATSNMSSNVQSNMNSMRSSFTSGASGIAQAWA 970 +G S M S+ ++ S++ + S + S + G Q Sbjct: 224 QMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQ 283 Query: 971 SAMQRITSITSSGMSAVRSASVSGMQAVVSAFRSGGQQAVSVTTSSMAACASVMRSAYGQ 1030 S+G + S+ ++G + +A Q A +T + A S + + YG Sbjct: 284 KGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQT-AQKGSDLTAGYGS 342 Query: 1031 FSSAGSYVMSGFIAGMNSQRGA 1052 +AG S IAG S + A Sbjct: 343 TGTAGDD--SSLIAGYGSTQTA 362 Score = 32.0 bits (72), Expect = 0.015 Identities = 61/253 (24%), Positives = 102/253 (40%), Gaps = 30/253 (11%) Query: 847 TATSQSGAMQAAVLGSVGGM-----------SAQTTG----LLAGMSGSAQAEFASLYSA 891 T T++ G+ A GS G S QT L AG + A S+ + Sbjct: 567 TQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTT 626 Query: 892 GSGQASSLNADVLSSLGGMSSQGVGDIASMTSGINS-----EFQNM-----SSTSSSATS 941 G G S+ AD G S+Q G + +T+G S E ++ S++++ A S Sbjct: 627 GYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADS 686 Query: 942 NMSSNVQSNMNSMRSSFTSGASGIAQAWASAMQRITSITSSGMSAVRSASVSGMQAVVSA 1001 ++ + S + +S + G Q + S+ + S+ ++G + +A Sbjct: 687 SLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTA 746 Query: 1002 FRSGGQQAVSVTTSSMAACASVMRSAYGQFSSAGSYVMSGFIAGMNSQRGAVMAT--AAS 1059 A +T + A SV+ + YG S+AG+ S IAG S + A + A Sbjct: 747 SYHSSLTAGYGSTQT-AREQSVLTTGYGSTSTAGAD--SSLIAGYGSTQTAGYHSILTAG 803 Query: 1060 IANAASAQIRSAL 1072 + +AQ RS L Sbjct: 804 YGSTQTAQERSDL 816 Score = 30.5 bits (68), Expect = 0.049 Identities = 70/298 (23%), Positives = 119/298 (39%), Gaps = 36/298 (12%) Query: 787 GMTATKTEEATGRMANATNINTAKMASDVTSN-SALMTSGFDVNM------NRMSMINDS 839 G T T EE+T + A + TA+ SD+T+ + T+G D ++ + + + S Sbjct: 405 GSTQTAGEEST-QTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSS 463 Query: 840 QWAMINGTATSQSGAMQAAVLGSVGGM-----------SAQTTG----LLAGMSGSAQAE 884 A T T+Q G+ A GS S QT G L AG + A+ Sbjct: 464 LTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQ 523 Query: 885 FASLYSAGSGQASSLNADVLSSLGGMSSQGVGDIASMTSGINS-----EFQNM-----SS 934 S G G S+ A+ G S+Q + +T+G S E ++ S+ Sbjct: 524 NESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGST 583 Query: 935 TSSSATSNMSSNVQSNMNSMRSSFTSGASGIAQAWASAMQRITSITSSGMSAVRSASVSG 994 ++ + S++ + S + S + G Q T S+ + S+ ++G Sbjct: 584 GTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAG 643 Query: 995 MQAVVSAFRSGGQQAVSVTTSSMAACASVMRSAYGQFSSAGSYVMSGFIAGMNSQRGA 1052 + +A + A +T + A S + + YG S+AG+ S IAG S + A Sbjct: 644 YGSTQTAGYNSILTAGYGSTQT-AQEGSDLTAGYGSTSTAGA--DSSLIAGYGSTQTA 698
>PF01540#Adhesin lipoprotein Length = 475 Score = 29.7 bits (66), Expect = 0.042 Identities = 19/63 (30%), Positives = 36/63 (57%), Gaps = 4/63 (6%) Query: 369 ERISNEIKETKKEANSYIVKLKKEF--DANFEEQTLSFAKAI--EQVKINAQSEVESAEK 424 ++I+NE E K N I +L+K+F D +F+EQ +FA + + +I+ + V S ++ Sbjct: 374 KKINNEAFELSKTVNKTIAELEKKFKIDVSFKEQLKNFADDLLDKSRQIDEFTTVTSTQE 433 Query: 425 RLS 427 + Sbjct: 434 GFT 436
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.020 Identities = 8/19 (42%), Positives = 15/19 (78%) Query: 126 TIVIQGDTGTGKSFLAFSI 144 T++I G++GTGK +A ++ Sbjct: 162 TLMITGESGTGKELVARAL 180
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 30.0 bits (67), Expect = 0.006 Identities = 16/36 (44%), Positives = 18/36 (50%) Query: 150 NGPINPENKDINNNPEKPPNNLNPGGLQGNGGKDPD 185 N P NP N D NNP+ P N NP N +PD Sbjct: 299 NNPDNPNNPDEPNNPDNPNNPDNPDNGDNNNSDNPD 334
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.3 bits (65), Expect = 0.026 Identities = 17/64 (26%), Positives = 24/64 (37%) Query: 240 ESNGYPTLEIEKGFTTLENADGTTYDVAHLEDNKFVLHAAIMGATLSGPAAENNFAKGKF 299 E N YPT K TT + D +KFV A + A+ + A + K+ Sbjct: 139 EKNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDAGTYNDQNKY 198 Query: 300 AYRV 303 V Sbjct: 199 PAFV 202
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 38.1 bits (88), Expect = 2e-04 Identities = 68/312 (21%), Positives = 130/312 (41%), Gaps = 37/312 (11%) Query: 77 LQKAQKEFKDTGNINKETMQSLQKEIKSVDWKSLDANSRDTFKTVIRNVNSVERNMNKLN 136 Q+A K KD + NKE + K+V DA + + V + +E+++ K Sbjct: 567 PQEANKLIKDFLSSNKELVGKTLNFNKAV----ADAKNTGNYDEVKKAQKDLEKSLRKRE 622 Query: 137 DVKFLEGLPDDAKEAGKHLLALQKDVEKTSKSLEKTDDKVD-FNKLNSELNKAKK----- 190 ++ KE K L + + K + K + F +N E N+ + Sbjct: 623 HLE---------KEVEKKLESKSGNKNKMEAKAQANSQKDEIFALINKEANRDARAIAYA 673 Query: 191 -ELQSTGKVADNTLDQINKDIKDVD--FESMSMSANVAFGKVEERAEQLDRKLRNVGEDV 247 L+ + + L+ +NK++KD D F+ N F K EE + L ++++G + Sbjct: 674 QNLKGIKRELSDKLENVNKNLKDFDKSFDEFKNGKNKDFSKAEETLKALKGSVKDLGINP 733 Query: 248 NLSNSTKNISEDID----GATGSVGGLKGAFKGLGPVIGGALATVSITEFTKKIVESTAE 303 + +N++ ++ G + A L + + +T+ + ++ + Sbjct: 734 EWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVIINQKVTDKVDNLNQAVSV 793 Query: 304 IEALN--SQYEQVMGKMKNTTDKYLGEMAQKYNVHPNELKKSMLQYQAI-------LKSK 354 +A S+ EQ + +KN + + L + AQK N N KKS + YQ++ L Sbjct: 794 AKATGDFSRVEQALADLKNFSKEQLAQQAQK-NESLNARKKSEI-YQSVKNGVNGTLVGN 851 Query: 355 GLNEQDAYETSK 366 GL++ +A SK Sbjct: 852 GLSQAEATTLSK 863
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 33.1 bits (75), Expect = 0.007 Identities = 47/295 (15%), Positives = 110/295 (37%), Gaps = 48/295 (16%) Query: 509 LKKNVSQQSKTHKATVQALSKAQRMYNTGSAIAKRGK----TSGKVTGKEDIAIGNLIMA 564 LKK ++Q+ KA +A +KA+ + A+ +R K + + + L A Sbjct: 62 LKKTQAEQAARAKAAAEAQAKAKANRD---ALTQRLKDIVNEALRHNASRTPSATELAHA 118 Query: 565 NMKNIGKLPVEKMQSNLNAINKKINSVIASNEGKIATLNNKIVKSSKSAEIKGASREIQN 624 N MQ+ + ++A K K +++AE A +E + Sbjct: 119 NNA--------AMQAEDERL-------------RLAKAEEKARKEAEAAEK--AFQEAEQ 155 Query: 625 RKNNIATLNSKIKKTSNKKLIAKYKKD-IKAHQRKISSLENKIKRATNNKVANNARADIA 683 R+ I ++ ++ + + + + + + K+ A + +I Sbjct: 156 RRKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSE--VVKMDGEIK 213 Query: 684 AYQAQINSLKKLKQSEVLKTNFLDSLVKHKQRLQNQLNKKNEERKALTESKMSFRDSIRD 743 ++++S + +E +K +N+L + + + K L E D Sbjct: 214 TLNSRLSSSIHARDAE----------MKTLAGKRNELAQASAKYKELDELVKKLSPRAND 263 Query: 744 SYRGLAGFEAAKGNTSKDFIAFMKYRLNRMKKFAANVSKLRQMGLDPTILREILA 798 + FEA + + K R + K+ A+ +++ ++ D T +++ ++ Sbjct: 264 PLQNRPFFEATRRR-----VGAGKIREEKQKQVTASETRINRINADITQIQKAIS 313
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.2 bits (104), Expect = 3e-08 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 1/97 (1%) Query: 32 ADPSIEMINRYISKSSIYILEQSKPIGVVVLKEVSESTIEIMNIAVSEAYHGKGYGKVML 91 D + + + +Y LE IG + ++ I +IAV++ Y KG G +L Sbjct: 53 DDMDVSYVEEEGKAAFLYYLEN-NCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALL 111 Query: 92 EEAEKIAKHSGYDKLIIATANSSLNQLALYQKCGFRI 128 +A + AK + + L++ T + +++ Y K F I Sbjct: 112 HKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>PF01540#Adhesin lipoprotein Length = 475 Score = 28.9 bits (64), Expect = 0.018 Identities = 15/45 (33%), Positives = 21/45 (46%) Query: 100 LKNVNEINKLARVIFKNVQKAPSKFFNVDSFFFSHLDNTVNLLNE 144 LK +I A I + K K F +D F L +T+ LLN+ Sbjct: 131 LKLSEKIQSFADTIALTITKLEGKKFQIDETFKKQLISTIELLNK 175
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.3 bits (63), Expect = 0.038 Identities = 28/130 (21%), Positives = 48/130 (36%), Gaps = 18/130 (13%) Query: 25 NVLLKGPTGSGKTKLAETL---GNELNLKMNSINC---SVDLDAESLLGYKTIENIDGES 78 +++ G +G+GK +A L G N +IN DL L G++ ++ Sbjct: 162 TLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQT 221 Query: 79 QIIFVDGPVLEAMREGNILYIDEINMAKPETLPILNGVLDYRKTITNPFT--GEVITAHE 136 EG L++DEI + L VL + +T G Sbjct: 222 -----RSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGE-----YTTVGGRTPIRS 271 Query: 137 NFKVIAAINV 146 + +++AA N Sbjct: 272 DVRIVAATNK 281
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.0 bits (213), Expect = 1e-21 Identities = 28/123 (22%), Positives = 62/123 (50%), Gaps = 2/123 (1%) Query: 3 RILVVEDEANLARFIELELTHESYAVTVMYDGESGLQEALSTEYDCILLDIMLPKLNGLE 62 ILV +D+A + + L+ Y V + + + + + + D ++ D+++P N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 VCRKLR-REKETPVIMITAKGETYDKVIGLDYGADDYIVKPFDIEELLARL-RALLRRNK 120 + +++ + PV++++A+ + + GA DY+ KPFD+ EL+ + RAL + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 NED 123 Sbjct: 125 RPS 127
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 53.7 bits (129), Expect = 2e-12 Identities = 15/77 (19%), Positives = 41/77 (53%), Gaps = 8/77 (10%) Query: 1 MKRMARRFKKQFSKDDGFTLIEMLLVLLVISILIIVIIPNIAKQSKTVQAKGCEAQVKMV 60 M+ ++ GFTL+E+++V+++I +L +++PN+ + + + + + Sbjct: 1 MRATDKQ--------RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVAL 52 Query: 61 QGQIEAYRIDTGKTPST 77 + ++ Y++D P+T Sbjct: 53 ENALDMYKLDNHHYPTT 69
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 91.4 bits (227), Expect = 1e-22 Identities = 55/265 (20%), Positives = 121/265 (45%), Gaps = 9/265 (3%) Query: 94 EQYGDLNMTLVRCYDYLESKAKLASQLIKTIQYPLILILIFITLIFTVNLTVLPQFQSMY 153 E G L+ L R DY E + ++ S++ + + YP +L ++ I ++ + V+P+ + Sbjct: 143 ETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVAIAVVSILLSVVVPKVVEQF 202 Query: 154 DTMDVNVGIEIKVMTAILFSLPYII--YSFILLFIALILAYTFYFRKQSVAGQLKI---L 208 M + + T +L + + + +L L F + ++ L Sbjct: 203 IHMKQ----ALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQEKRRVSFHRRL 258 Query: 209 LSVPLIRDLYRLYITYRFSEMLSFFLSNGVMMKRILQILSSQNKNETFRYIALMINHKLL 268 L +PLI + R T R++ LS ++ V + + ++I N+ R+ + + Sbjct: 259 LHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMSNDYARHRLSLATDAVR 318 Query: 269 EGRPLPAAVKDMNIFEPSLVQFMEHGERNSKLDKELKYYSEFIFDRFQHRLLRCIKAIQP 328 EG L A++ +F P + + GER+ +LD L+ ++ F ++ + +P Sbjct: 319 EGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQDREFSSQMTLALGLFEP 378 Query: 329 VIFMILALLIVTMYLVIILPMLQMM 353 ++ + +A +++ + L I+ P+LQ+ Sbjct: 379 LLVVSMAAVVLFIVLAILQPILQLN 403
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.5 bits (76), Expect = 0.001 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 14/78 (17%) Query: 127 KSSGIIIISGPTGSGKSTLMYQLV---HFAKDTLKRQVISIEDPVEQHLDGIIQVNVNE- 182 K +++ G G GKSTL+ LV F+ DT + + +D EQ + GI+ ++E Sbjct: 594 KFDYSVVLEGTGGIGKSTLINTLVGLDFFS-DTH-FDIGTGKDSYEQ-IAGIVAYELSEM 650 Query: 183 ----KAEITYQTAIKAIL 196 +A+ A+KA Sbjct: 651 TAFRRADA---EAVKAFF 665
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 168 bits (426), Expect = 5e-49 Identities = 81/365 (22%), Positives = 144/365 (39%), Gaps = 62/365 (16%) Query: 2 SKVIGIDLGTTNSCVAVLEGG----EPKVIA-NPEGNRTTPSVVAFKNGETQVGEVAKRQ 56 S + IDLGT N+ + V G EP V+A + + SV A VG AK+ Sbjct: 10 SNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAA-------VGHDAKQM 62 Query: 57 AITNPNTIISIKRHMGTDYKENIEGKEYSPQEISAMILQNLKATAESYLGEKVTKAVITV 116 P I +I+ K+ + + +++ ++ + + S++ + ++ V Sbjct: 63 LGRTPGNIAAIR-----PMKDGVIADFFVTEKMLQHFIK--QVHSNSFMRPS-PRVLVCV 114 Query: 117 PAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKEQKVLVFDLGGGTFDV 176 P ER+A +++ + AG +I EP AAA+ GL + +V D+GGGT +V Sbjct: 115 PVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGL-PVSEATGSMVVDIGGGTTEV 173 Query: 177 SILELGDGVFEVLSTSGDNKLGGDDFDQVIIDYLVEEFKKENGLDLSQDKMAMQRLKDAA 236 +++ L V S ++GGD FD+ II+Y+ + G + A Sbjct: 174 AVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYGSLIG-------------EATA 215 Query: 237 EKAKKDLS----GVSSTQISLPFISAGEAGPLHLEVTLSRAKFEELSHTL---------- 282 E+ K ++ G +I + + E P + S E L L Sbjct: 216 ERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLN-SNEILEALQEPLTGIVSAVMVA 274 Query: 283 VERTMGPTRQAMKDAGLSNADIDEVILVGGSTRIPAVQEAIKKELGKEPNKGVNPDEVVA 342 +E+ + + G ++L GG + + + +E G +P VA Sbjct: 275 LEQCPPELASDISERG--------MVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVA 326 Query: 343 MGAAI 347 G Sbjct: 327 RGGGK 331
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 178 bits (452), Expect = 2e-50 Identities = 97/444 (21%), Positives = 177/444 (39%), Gaps = 97/444 (21%) Query: 12 RIRNFSIIAHIDHGKSTLADRILEN---TKSVATREMKAQLLDSMDLERERGITIKLNAV 68 +I N ++AH+D GK+TL + +L N + + + D+ LER+RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 QLNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLA 128 + E ++IDTPGH+DF EV RSL+ +GAIL++ A G++AQT + Sbjct: 62 SFQW-----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 129 LDNELELIPVINKIDLPAAEPER--------------VRQEIEDVIG------------- 161 + I INKID + ++Q++E Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 162 --LDASDAVLA--------------------------------SAKANIGIEDILEQIVE 187 ++ +D +L SAK NIGI++++E I Sbjct: 177 TVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITN 236 Query: 188 LVPPPMGDPEAPLKALIFDSAFDAYRGVISSIRIIDGTVKAGDKIKMMATGKEFEVVEVG 247 ++ L +F + R ++ IR+ G + D +++ K ++ E Sbjct: 237 KFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-KITE-- 293 Query: 248 INTPKQ---MPVAELTVGDVGYLTASI----KNVGDSRVGDTITHASNPASEPLQGYKKM 300 + T + + G++ L +GD+++ NP Sbjct: 294 MYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENP----------- 342 Query: 301 NPMVFCGVYPIDTGKYNDLREALEKLQLNDASLEFE--PETSQALGFGFRVGFLGLLHME 358 P++ V P + L +AL ++ +D L + T + + + FLG + ME Sbjct: 343 LPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEII-----LSFLGKVQME 397 Query: 359 IIQERIEREFGIELIATAPSVIYK 382 + ++ ++ +E+ P+VIY Sbjct: 398 VTCALLQEKYHVEIEIKEPTVIYM 421 Score = 46.8 bits (111), Expect = 2e-07 Identities = 18/82 (21%), Positives = 31/82 (37%), Gaps = 2/82 (2%) Query: 408 IYEPYVKASIMVPNDYVGAVMELCQKKRGNFQTMDYLDDIRVNIIYEVPLSEVVFDFFDQ 467 + EPY+ I P +Y+ K N ++ V + E+P + ++ Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNE-VILSGEIPARC-IQEYRSD 592 Query: 468 LKSSTKGYASFDYELIGYQESK 489 L T G + EL GY + Sbjct: 593 LTFFTNGRSVCLTELKGYHVTT 614
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 27.6 bits (61), Expect = 0.034 Identities = 8/25 (32%), Positives = 15/25 (60%) Query: 28 KVNDVVVKKSDIKIVPENDTVTVYD 52 ++N V+ + P+ DT+TV+D Sbjct: 12 RMNAPAVRVAKTMQTPKGDTITVFD 36
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 54.4 bits (131), Expect = 3e-10 Identities = 64/372 (17%), Positives = 128/372 (34%), Gaps = 26/372 (6%) Query: 1 MKMPKIVWLLVIGMAVNVTGSSLIWPLNTIYLHNELGKSLSLA---GFVLMLNSGASVLG 57 MK + + +++ +A++ G LI P+ L +L S + G +L L + Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLL-RDLVHSNDVTAHYGILLALYALMQFAC 59 Query: 58 NLLGGTLFDKIGGYRSILIGIVISGISLLGIIFLHGWPWYAVWLV----ILGFGSGIVFP 113 + G L D+ G +L+ + + + + +W++ I+ +G Sbjct: 60 APVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP-----FLWVLYIGRIVAGITGATGA 114 Query: 114 SIYAMAGSAWPEGGR-KTFNAIYISQNLGVALGAALGGFIADLSFTYIFILNFLMYAVFF 172 A R + F + G+ G LGG + S F + + F Sbjct: 115 VAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNF 174 Query: 173 FIAFFGYRSAKPIATGSNVMRDVGNIKDKTKFNALLMVCTAYCLCWIGYVQW------QS 226 F + + R+ + F + L + ++ + Sbjct: 175 LTGCFLLPESHK-GERRPLRREA--LNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAA 231 Query: 227 TISSYTQD-LGIPLKAYSSLWAINGVLIIAGQPLIAPVINRLSTRIKTQIAIGFVIFIVS 285 + +D A G+L Q +I + + + +G + Sbjct: 232 LWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAA-RLGERRALMLGMIADGTG 290 Query: 286 YIVTSFADTFLMFMLGMVILTIGEMFVWPAVPTIANMLAPKGRTGVYQGIVNSTATLGRA 345 YI+ +FA M MV+L G + + PA+ + + + R G QG + + +L Sbjct: 291 YILLAFATRGWMAFPIMVLLASGGIGM-PALQAMLSRQVDEERQGQLQGSLAALTSLTSI 349 Query: 346 IGPLLGGFLVDA 357 +GPLL + A Sbjct: 350 VGPLLFTAIYAA 361
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.013 Identities = 16/69 (23%), Positives = 32/69 (46%), Gaps = 4/69 (5%) Query: 75 DQKIVGMIHIRHYLNAYLNNVGGHIGYSVRPDERRQGIAKWMLHQALLFLQTKGAKKALV 134 + +G I IR N Y + I +V D R++G+ +LH+A+ + + ++ Sbjct: 73 ENNCIGRIKIRSNWNGYA--LIEDI--AVAKDYRKKGVGTALLHKAIEWAKENHFCGLML 128 Query: 135 TCDHNNIAS 143 NI++ Sbjct: 129 ETQDINISA 137
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 30.3 bits (68), Expect = 0.006 Identities = 13/29 (44%), Positives = 15/29 (51%) Query: 174 PKKPVVKQAPKPAPKPAAKPVAKQPATKA 202 + PVV + PKP PKP KPV K Sbjct: 83 KEAPVVIEKPKPKPKPKPKPVKKVQEQPK 111
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.4 bits (146), Expect = 1e-13 Identities = 33/173 (19%), Positives = 67/173 (38%), Gaps = 8/173 (4%) Query: 8 EEKKHLILEIAYHNIQELGKQGTSVRSIANAAKMTPGQIRYYFPNQSALLSEILNMLTES 67 +E + IL++A + G TS+ IA AA +T G I ++F ++S L SEI + + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 68 IESNIKSIFLDRNIPLEKRIVDAILLTMPLD---KKRTADMIVWLAVQE-----ENSAIN 119 I + + ++ + ++R M + E Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 120 ENTMSDEIYILLQTSFELLQQANKINESIDKEKAITKLHALIDGLALHKLYQP 172 + + E Y ++ + + +A + + +A + I GL + L+ P Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 155 bits (393), Expect = 1e-43 Identities = 69/209 (33%), Positives = 94/209 (44%), Gaps = 31/209 (14%) Query: 199 PSITHLKVDKVWELGNKGKGVKVGVIDTGIDYNHPDLKDVYKGGRNYVGGGDYNTKRNAD 258 + ++ VW +G+GVKV V+DTG D +HPDLK GGRN+ + + + D Sbjct: 24 RGVEMIQAPAVWNQT-RGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKD 82 Query: 259 DPYETKPEERPGHLPEVNESGSEYYTTHGTHVAGTIAAQGKNEFGMYGIAPNVDLYAYRV 318 HGTHVAGTIAA NE G+ G+AP DL +V Sbjct: 83 Y------------------------NGHGTHVAGTIAATE-NENGVVGVAPEADLLIIKV 117 Query: 319 LGAYGRGSTSWIVGGIEDAVKDDMDVINLSLGNSSPEENQANAMAVNNAMLLGVTANVAT 378 L G G WI+ GI A++ +D+I++SLG PE+ AV A+ + A Sbjct: 118 LNKQGSGQYDWIIQGIYYAIEQKVDIISMSLG--GPEDVPELHEAVKKAVASQILVMCAA 175 Query: 379 GNSGPERS---TIGGPATSPLGIGVGNTT 404 GN G +G P I VG Sbjct: 176 GNEGDGDDRTDELGYPGCYNEVISVGAIN 204 Score = 78.3 bits (193), Expect = 2e-17 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 23/126 (18%) Query: 549 TTPGDDVNDSSSRGPSLPNFDIKPDVSAPGTNILSTIPSFAVGDDYSKAYAQYTGTSMAT 608 ++ S+ D+ APG +ILST+P YA ++GTSMAT Sbjct: 203 INFDRHASEFSNSNNE-------VDLVAPGEDILSTVPG--------GKYATFSGTSMAT 247 Query: 609 PHISGVSALLKEL-----HPEWTPFDIKSALSNTAKHLDKSKFDVFSQGAGLVQPLEAAT 663 PH++G AL+K+L + T ++ + L L S +G GL+ Sbjct: 248 PHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKM---EGNGLLYLTAVEE 304 Query: 664 ATSLFK 669 + +F Sbjct: 305 LSRIFD 310
>adhesinb#Adhesin B signature. Length = 310 Score = 30.6 bits (69), Expect = 0.046 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 9/83 (10%) Query: 232 QFNLPQRYIWGIYEPESNEQNMTLERLTTLATTELNKRKSASISYEISVADIEEEYSHEI 291 +N+P YIW I + E+ T +++ TL L K K S+ E SV D + Sbjct: 215 AYNVPSAYIWEI----NTEEEGTPDQIKTLVEK-LRKTKVPSLFVESSVDD----RPMKT 265 Query: 292 VRYGDLVRIKNSDFTPSLYAESE 314 V + I FT S+ + E Sbjct: 266 VSKDTNIPIYAKIFTDSVAEKGE 288
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.7 bits (87), Expect = 3e-04 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 5/104 (4%) Query: 38 EEFKANMSAVKRTGSEMDILATRTNGLSKKYEAQKKVVEEMTKAYEKANEQASSDKATQK 97 E K + ++ + I L + +A ++ +++ KA E+AN + + A +K Sbjct: 358 EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLA---ALEK 414 Query: 98 QIKDAEAKKKALNKEIATLNDLGGALQDAQREQDELAEHNKKLE 141 K+ E KK KE A L A A +E+ LA+ ++L Sbjct: 415 LNKELEESKKLTEKEKAELQAKLEAEAKALKEK--LAKQAEELA 456 Score = 33.1 bits (75), Expect = 0.009 Identities = 21/113 (18%), Positives = 36/113 (31%), Gaps = 17/113 (15%) Query: 53 EMDILATRTNGLSKKYEAQKKVVEEMTKAYEKANEQASSDKATQKQIKDAE--------- 103 L G A ++ + + + + Q Q+ +A Sbjct: 261 RQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLE-HQSQVLNANRQSLRRDLD 319 Query: 104 ---AKKKALNKEIATLNDLGG----ALQDAQREQDELAEHNKKLESTFYKLDE 149 KK L E L + + Q +R+ D E K+LE+ KL+E Sbjct: 320 ASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEE 372
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.0 bits (80), Expect = 3e-04 Identities = 28/154 (18%), Positives = 47/154 (30%), Gaps = 1/154 (0%) Query: 76 QKGDTLEKIAKKFDTKVADLKRWNSIETNKALKVGKLIIVDKDEKRQIVTQTAAQQAPVT 135 Q+ T+EK + A + + + V + TQT + T Sbjct: 1046 QESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETAT 1105 Query: 136 VQQTVAYQAPAVKAPEQAAKPAAQAAKPAAQKPVQQVAQQPAAQQPQQVAQQPQQAAQKP 195 V++ + K E + + K + VQ A+ P ++PQ Sbjct: 1106 VEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTT 1165 Query: 196 VAQAAPAG-NSSMDAHLRVIAQRESGGNPNAVNP 228 PA SS + + GN NP Sbjct: 1166 ADTEQPAKETSSNVEQPVTESTTVNTGNSVVENP 1199
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.016 Identities = 11/82 (13%), Positives = 28/82 (34%) Query: 55 RQAGITADLDNAKRQNEEAKHYAEENKALLAKTQQEVSVIMEDAKKQAKTQQEEIIHEAN 114 + T + + + E+ K KTQ+ V + + KQ +++ + E Sbjct: 1087 QSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPA 1146 Query: 115 MRANKIVSDAQVEIENEKQRAI 136 + V+ + + + Sbjct: 1147 RENDPTVNIKEPQSQTNTTADT 1168
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 56.5 bits (136), Expect = 3e-11 Identities = 32/161 (19%), Positives = 63/161 (39%), Gaps = 7/161 (4%) Query: 124 NLGSLKEPNFEKLAEMQPDLILISGRQANQKVMDEMKKAAPKAQIVYVGADDKNYIDSIK 183 ++G EPN E L EM+P ++ S + + + AP + +D K + + Sbjct: 80 DVGLRTEPNLELLTEMKPSFMVWSAGY--GPSPEMLARIAPG--RGFNFSDGKQPLAMAR 135 Query: 184 VNTENIGKIFGKEKETEKLIADIDKKIKEVKAMTEKSDKK--GLFVLANEGELSVFGKGG 241 + + + + E +A + I+ +K K + L L + + VFG Sbjct: 136 KSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNS 195 Query: 242 RFGFIHDVLGVKETDQNITAKGHGQVINFEYINK-KNPDII 281 F I D G+ Q T ++ + + K+ D++ Sbjct: 196 LFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVL 236
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.004 Identities = 14/45 (31%), Positives = 19/45 (42%), Gaps = 7/45 (15%) Query: 34 GPNGAGKSTLLSAITRLSDFDKGTVQLNDTEISKMKSDDIAMQLA 78 G G GKSTL++ + L F +DT D Q+A Sbjct: 603 GTGGIGKSTLINTLVGLDFF-------SDTHFDIGTGKDSYEQIA 640
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 31.5 bits (71), Expect = 0.007 Identities = 21/81 (25%), Positives = 31/81 (38%), Gaps = 14/81 (17%) Query: 26 VWAIAYGSSIGWGAFILPGDWIKSAGPIGATVGILLGALLMI--------------VIAV 71 +W + W A+I PGDW++ P A + GA ++ V + Sbjct: 39 MWVRLSDAEKRWSAWIKPGDWLEHVSPALAGAAVSAGAEHLVVPWLAATERPFELPVPHL 98 Query: 72 SYGALVEKFPVSGGAFAFGYL 92 S L + PV G A G L Sbjct: 99 SCRRLCVENPVPGSALPEGKL 119
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 65.2 bits (159), Expect = 6e-14 Identities = 60/310 (19%), Positives = 113/310 (36%), Gaps = 63/310 (20%) Query: 1 MNIFLTGATGFVGAQLINKLLQNSNHHLYI----LYRDEARKNKLITKENESRLHFVQGD 56 M +TGA GF+G + +LL+ + + I Y D + K + + F + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 57 ITLPNCGLENNVIKMFPEMDYFYHLAAL--VKFDEELRKDLFNINYHGTLHALNLAQNLN 114 + + ++ + + V++ E + N G L+ L ++ Sbjct: 61 LA--DREGMTDLFASG-HFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK 117 Query: 115 TKHFLYVSTAYTVGTSEYA--KEVLHPMGTPVNNPYEESKIKAE---HAVAES-GLTYSI 168 +H LY S++ G + + PV + Y +K E H + GL + Sbjct: 118 IQHLLYASSSSVYGLNRKMPFSTD-DSVDHPV-SLYAATKKANELMAHTYSHLYGLPATG 175 Query: 169 LRPAIIIGDSVTGEADSKFTLYGF-----MKALKVFKRKMERKGLLDKQSFRLFADNNCT 223 LR FT+YG M AL F + M L+ +S ++ Sbjct: 176 LR---------------FFTVYGPWGRPDM-ALFKFTKAM-----LEGKSIDVYNYGKMK 214 Query: 224 SNLVPVDYVV----RVLTHAIPHAEHEM---------------IYHITNNQPPENLKVLE 264 + +D + R+ IPHA+ + +Y+I N+ P E + ++ Sbjct: 215 RDFTYIDDIAEAIIRLQ-DVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQ 273 Query: 265 MIKRHLQFDA 274 ++ L +A Sbjct: 274 ALEDALGIEA 283
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 54.5 bits (131), Expect = 3e-10 Identities = 59/342 (17%), Positives = 115/342 (33%), Gaps = 50/342 (14%) Query: 65 GKNIDILGQKKVLVIGVLIFTITTALYFASFNLA-LLLAIRFLNGMGNG-IASTATGTIA 122 GK D LG K++L+ G++I + + F + LL+ RF+ G G + +A Sbjct: 70 GKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVA 129 Query: 123 AFITPIKRRGEGISYFSMSTVMATAIGPFLGLSLLQFISYRQLFIFCLVLAVIGLLMVPQ 182 +I + RG+ M +GP +G + +I + L + ++ + ++ Sbjct: 130 RYIPK-ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKL 188 Query: 183 VKVSHEVKS-------------------MTSHAPKGFHI-----------------SDYI 206 +K +K T+ F I ++ Sbjct: 189 LKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFV 248 Query: 207 DI---NAIPISIVVLICCTAYSSVLSFISFFAEENNLI------TAGSFFFLTYALVVLI 257 D IP I VL + +V F+S + GS + V+I Sbjct: 249 DPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVII 308 Query: 258 SRPITGKLMDSKGTNIVMYPALISFFLGLLCLSIT--HAAWTLILSAALLGFGYGNFQSI 315 I G L+D +G V+ + + L S +W + + + G +++ Sbjct: 309 FGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTV 368 Query: 316 AQATAVKVTDHEKMGLATSTYFIFLDFALGFGPYVLGLFIPV 357 ++ G S + G G ++G + + Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410 Score = 30.6 bits (69), Expect = 0.012 Identities = 26/138 (18%), Positives = 49/138 (35%), Gaps = 1/138 (0%) Query: 251 YALVVLISRPITGKLMDSKGTNIVMYPALISFFLGLLCLSITHAAWT-LILSAALLGFGY 309 + L I + GKL D G ++ +I G + + H+ ++ LI++ + G G Sbjct: 58 FMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGA 117 Query: 310 GNFQSIAQATAVKVTDHEKMGLATSTYFIFLDFALGFGPYVLGLFIPVLGLHGLYRYMSI 369 F ++ + E G A + G GP + G+ + L I Sbjct: 118 AAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMI 177 Query: 370 LVIIGMVAYYMLHGKKAH 387 +I +L + Sbjct: 178 TIITVPFLMKLLKKEVRI 195
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 62.9 bits (153), Expect = 5e-13 Identities = 83/373 (22%), Positives = 144/373 (38%), Gaps = 32/373 (8%) Query: 1 MKKDNKLILILTLGLLAAFGPLSLDMYLPALPRVADDLSTGASFAQLSLTACMIGL-AVG 59 MK + LI+IL+ L A G + + +P LP + DL S + ++ L A+ Sbjct: 1 MKPNRPLIVILSTVALDAVG---IGLIMPVLPGLLRDL--VHSNDVTAHYGILLALYALM 55 Query: 60 QIIVGPI----SDVIGRKKPLFIVLIGYALFSYFAARAATIEWLILFRFIQGFCGGAGAV 115 Q P+ SD GR+ L + L G A+ A A + L + R + G G GAV Sbjct: 56 QFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAV 115 Query: 116 LSRAISSDLYKGKDLTKFLAVLMLVNGLAPVIAPVLGGVILSISTWHTVFYILSVYGVVM 175 I +D+ G + + + G V PVLGG++ S H F+ + + Sbjct: 116 AGAYI-ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP-HAPFFAAAALNGLN 173 Query: 176 VLLSLTLEESLPKPSRNEGALKSIWKDFKSLLTNKAFVTMLMLQSLTYGI-LFSYISGSP 234 L L K R +++ S + + L ++ + + L + + Sbjct: 174 FLTGCFLLPESHKGERRPLRREAL-NPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL 232 Query: 235 FITQKIYDMNAQQFSYLFALNGIGLIG-FSQ--LTAKLVNKMDELKILKLGQNIQLVGVI 291 ++ + + +L G++ +Q +T + ++ E + L LG G I Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 292 LTVIVLLFHLPVWM-----LCTAFFLMITPVSMIGTTGFSVAMQVQNQGAGSASAILGLM 346 L L F WM + A + P ++ V + Q Q GS +A+ L Sbjct: 293 L----LAFATRGWMAFPIMVLLASGGIGMP-ALQAMLSRQVDEERQGQLQGSLAALTSL- 346 Query: 347 QFLIGGILSPLVG 359 I+ PL+ Sbjct: 347 ----TSIVGPLLF 355
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 45.2 bits (107), Expect = 2e-07 Identities = 32/163 (19%), Positives = 65/163 (39%), Gaps = 10/163 (6%) Query: 10 FSICFLFLFSYKALAKEPYEIANDAGNYIDASYNPK-GTIVIAQKNGQVLYSDDADTKWP 68 +C + L + LA + ++ + + G I + +G+ L + AD ++P Sbjct: 4 IRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFP 63 Query: 69 LASMSKLMTLYLLLQEMDKGEITFNTKVKVTDKFYNISKLPALSNNNLRLNAVYTVDELM 128 + S K++ +L +D G+ K+ + + P + L TV EL Sbjct: 64 MMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDL-VDYSPVSEKH---LADGMTVGELC 119 Query: 129 PIMLTNSSNAATYMLSSLVTKNDSEFIDKMNQEAKRLGMNSTK 171 +T S N+A +L + V + +++G N T+ Sbjct: 120 AAAITMSDNSAANLLLATVGG-----PAGLTAFLRQIGDNVTR 157
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 621 bits (1603), Expect = 0.0 Identities = 230/1060 (21%), Positives = 458/1060 (43%), Gaps = 69/1060 (6%) Query: 5 IIDFSLHNKLAVWLMTLIILSAGVYSAMKMKMEMLPSMSTPVISITTPYPGATPEDVLNG 64 + +F + + W++ +I++ AG + +++ + P+++ P +S++ YPGA + V + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 VTDPIEKKVKNLSSVDKVTSQSLENASA-VTVQYKFGTDMDKAQSELEKQIDKV--DLPE 121 VT IE+ + + ++ ++S S S +T+ ++ GTD D AQ +++ ++ LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 GAQEKQISQMSMYTFPIISYSLSSDKADI--KDLTKRIKEDLVPEIEGVEGVTNVTFSGQ 179 Q++ IS + ++ SD D++ + ++ + + GV +V G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 EVEQVELQFDDKKLKKNNLTEESVLQFIKGATTDAPLG-----LYTFGNDL-KSIIVNGQ 233 + + + D L K LT V+ +K G G L SII + Sbjct: 181 Q-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 FTSVDALKDLKIPLSGGDNQANTAKASPEAQAALAKMMQAGKVPTVKLSDIATIK-NVES 292 F + + + + + + + V+L D+A ++ E+ Sbjct: 240 FKNPEEFGKVTL------------RVNSDGS-------------VVRLKDVARVELGGEN 274 Query: 293 RESISKTNGKDSLSIQVIKSDDANTVALANDVKDKVKEFKKNN-KDINAVLMMDQAKPIE 351 I++ NGK + + + + AN + A +K K+ E + + + + D ++ Sbjct: 275 YNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQ 334 Query: 352 DSVKTMAEKAIIGALFAVIMILVFLRNIRSTMIAVVSIPMSILMAMLILKQMDISLNIMT 411 S+ + + + +++ +FL+N+R+T+I +++P+ +L IL S+N +T Sbjct: 335 LSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLT 394 Query: 412 LGAMTVAIGRVIDDSIVVIENIFRRMSDPKEKLRGSELISSATKEMFIPIMSSTMVTIAV 471 + M +AIG ++DD+IVV+EN+ R M + +KL E + ++ ++ MV AV Sbjct: 395 MFGMVLAIGLLVDDAIVVVENVERVMME--DKLPPKEATEKSMSQIQGALVGIAMVLSAV 452 Query: 472 FLPLGLVSGSIGEIFRPFAYTVVFALLASLLIAITIVPMLGHTFFKNGIKGHHDDEAK-- 529 F+P+ GS G I+R F+ T+V A+ S+L+A+ + P L T K HH+++ Sbjct: 453 FIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFF 512 Query: 530 ------VGRIASFYHNVLEWSLKHKLIVSLLSIGLLLGSLFLTPFLGTSFISTGEDKFLA 583 + Y N + L L+ ++ G + L L +SF+ + Sbjct: 513 GWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFL 572 Query: 584 LTYKPKPGETEEEVVKKGEQVQKTLAENNDVVNIQ--YSVGGENPFNPVATNDMAMMV-- 639 + G T+E K +QV N+ N++ ++V G + F+ A N V Sbjct: 573 TMIQLPAGATQERTQKVLDQVTDYYL-KNEKANVESVFTVNGFS-FSGQAQNAGMAFVSL 630 Query: 640 ----EYKKDTPKWESEAERVLNKIASFKHEGTWKNQ-----DFATGGSTNTVTVTVNGPS 690 E D E+ R ++ + + T + + G Sbjct: 631 KPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLG 690 Query: 691 MNEIRPVIEQLEKEMKDV-KTVTNVSSSLTDSYDAYTLKVDHNKLSERGLTAGQIAMALN 749 + + QL ++ +V + + + L+VD K G++ I ++ Sbjct: 691 HDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTIS 750 Query: 750 QRSDNKVVTKIGDNGKSTDVVLTKEKETKWTKDKLENTKITSPLGKEVKLSDVVTIEEGK 809 V D G+ + + + + + + ++ + S G+ V S T Sbjct: 751 TALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVY 810 Query: 810 TSDTIKREDGNISASVEGKI-KGKDVSQATQDVAKKVNALKHPSNVDVHIGGTSEDIGES 868 S ++R +G S ++G+ G A + + L P+ + G S S Sbjct: 811 GSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKL--PAGIGYDWTGMSYQERLS 868 Query: 869 FSQLGLAMLAAIGIVYLILVLTFKGGLAPLAILFSLPFTIIGVILGLLAFGETLSVPSMI 928 +Q + + +V+L L ++ P++++ +P I+GV+L F + V M+ Sbjct: 869 GNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMV 928 Query: 929 GMLMLIGIVVTNAIVLIDRVIN-KEAEGLTTRDALLEAATTRVRPILMTALATVGALLPL 987 G+L IG+ NAI++++ + E EG +A L A R+RPILMT+LA + +LPL Sbjct: 929 GLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPL 988 Query: 988 LFGGDGSVLISKALAVTVIGGLTSSTLLTLIVVPVVYEIL 1027 A+ + V+GG+ S+TLL + VPV + ++ Sbjct: 989 AISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028 Score = 116 bits (293), Expect = 1e-28 Identities = 89/530 (16%), Positives = 213/530 (40%), Gaps = 50/530 (9%) Query: 544 SLKHKLIVSLLSIGLLLGSLFLTPFLGTSFISTGEDKFLALTYK------PKPGETEEEV 597 ++ + +L+I L++ + + ++ + PG + V Sbjct: 5 FIRRPIFAWVLAIILMMAGAL-------AILQLPVAQYPTIAPPAVSVSANYPGADAQTV 57 Query: 598 VKKGEQVQKTLAEN-NDVVNIQYSVGGENPFNPVATNDMAMMV--EYKKDTPKWESEAER 654 + V + + +N N + N+ Y + + + ++ + ++ T ++ + Sbjct: 58 Q---DTVTQVIEQNMNGIDNLMY-------MSSTSDSAGSVTITLTFQSGTDPDIAQVQ- 106 Query: 655 VLNKIASFKH------EGTWKNQDFATGGSTNTVTVTVNGPSMNEI---RPVIEQLEKEM 705 V NK+ + + + ++ + P + V ++ + Sbjct: 107 VQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTL 166 Query: 706 KDVKTVTNVSSSLTDSYDAYTLKVDHNKLSERGLTAGQIAMALNQRSDNKVVTKIGD--- 762 + V +V L + A + +D + L++ LT + L ++D ++G Sbjct: 167 SRLNGVGDVQ--LFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPA 224 Query: 763 -NGKSTDVVLTKEKETKWTKDKLENTKITSPLGKEVKLSDVVTIEEGKTSDTIK-REDGN 820 G+ + + + K ++ + T + G V+L DV +E G + + R +G Sbjct: 225 LPGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK 284 Query: 821 ISASVE-GKIKGKDVSQATQDVAKKVNALK--HPSNVDVHIG-GTSEDIGESFSQLGLAM 876 +A + G + + + K+ L+ P + V T+ + S ++ + Sbjct: 285 PAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTL 344 Query: 877 LAAIGIVYLILVLTFKGGLAPLAILFSLPFTIIGVILGLLAFGETLSVPSMIGMLMLIGI 936 AI +V+L++ L + A L ++P ++G L AFG +++ +M GM++ IG+ Sbjct: 345 FEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGL 404 Query: 937 VVTNAIVLIDRVIN-KEAEGLTTRDALLEAATTRVRPILMTALATVGALLPLLFGGDGSV 995 +V +AIV+++ V + L ++A ++ + ++ A+ +P+ F G + Sbjct: 405 LVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 996 LISKALAVTVIGGLTSSTLLTLIVVPVVYEILMNLKQRFTKDEKNIDPFI 1045 I + ++T++ + S L+ LI+ P + L LK + +N F Sbjct: 465 AIYRQFSITIVSAMALSVLVALILTPALCATL--LKPVSAEHHENKGGFF 512
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 176 bits (447), Expect = 1e-53 Identities = 91/362 (25%), Positives = 173/362 (47%), Gaps = 14/362 (3%) Query: 4 QFKLLMMIQFFIYFGFSIVIPVIPALVHSLNLN---AFHMGLLLASYSIVSFIVAPMWGY 60 +++ G +++PV+P L+ L + H G+LLA Y+++ F AP+ G Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 61 LSDKYGRKKILIIGLIGFTLSFVLFGLFIDNLPMLYTSRILGGLFSGACFSTTTSMVSDM 120 LSD++GR+ +L++ L G + + + L +LY RI+ G+ +GA + + ++D+ Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMA-TAPFLWVLYIGRIVAGI-TGATGAVAGAYIADI 123 Query: 121 TTHEERNKYMGLMGMMIGLGFIFGPAVGGLLSGISYQIPYFVTAAILTVIALFCLFTIQE 180 T +ER ++ G M G G + GP +GGL+ G S P+F AA+ + L F + E Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 181 TLQHSTDSEQ-------ATVNPKLLTPAVYMLLLSTFIVTFTMSGMESSFQLFEIEKINI 233 + + + A+ V L+ FI+ + + +F ++ + Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHW 243 Query: 234 TATQMGMLFMIGGLVNAGLQGGYLRKV-KHGQEKPVIITGQLITIVAFIMLPFSMNLFYA 292 AT +G+ G++++ Q V E+ ++ G + +I+L F+ + A Sbjct: 244 DATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMA 303 Query: 293 GLCLVLLMSGNALVRTLLTSQLTKETSSNKMGKLTSISYSMDSLGRILGPLLFTALLSRH 352 +VLL SG + L + L+++ + G+L ++ SL I+GPLLFTA+ + Sbjct: 304 FPIMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362 Query: 353 LE 354 + Sbjct: 363 IT 364
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 29.2 bits (65), Expect = 0.027 Identities = 13/42 (30%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Query: 31 EQLLKKVDFSHEDILIINGDIIDKGPDSIQMITYVERLMAQG 72 +Q+ + + + EDI D++D+G DS++++T VE+ +G Sbjct: 237 KQIAELLQETPEDI-TDQEDLLDRGLDSVRIMTLVEQWRREG 277
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 125 bits (315), Expect = 6e-37 Identities = 73/256 (28%), Positives = 127/256 (49%), Gaps = 12/256 (4%) Query: 5 LKDKVVVITGASSGIGKAMAEQFGAEGCKVVA-NYNSSESEALEIAETIKKSGGDAITIQ 63 ++ K+ ITGA+ GIG+A+A ++G + A +YN + E + + + +A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF--P 63 Query: 64 ADVSKENEVTALISEAVKHFGTMDIMINNAGFEKATPSLEMSAEDFNHVMNINLTGAFVG 123 ADV + + + + G +DI++N AG + +S E++ ++N TG F Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 124 SREAAKHFTQTKKKGVIINMSSVHDVIPWPNYVNYAASKGGLKLMMETLSMEFAPHGIRV 183 SR +K+ ++ G I+ + S +P + YA+SK + + L +E A + IR Sbjct: 124 SRSVSKYM-MDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 184 NNISPGAIVTEHTKEKFSDPATREETERM--------IPMGFIGEPEHVANAALFLASTQ 235 N +SPG+ T+ ++D E+ + IP+ + +P +A+A LFL S Q Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 236 ADYITGTTLYVDGGMT 251 A +IT L VDGG T Sbjct: 243 AGHITMHNLCVDGGAT 258
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 5e-05 Identities = 28/119 (23%), Positives = 47/119 (39%), Gaps = 12/119 (10%) Query: 164 KYKPVYKKSFTEIMKDMYIDYKPRRDKILNSIGSSHELYLYLNEGIAKGFIWMQINDDDS 223 ++ Y K + + DM + Y K +LY E G I ++ N + Sbjct: 41 RFSKPYFKQYED--DDMDVSYVEEEGKAA---------FLYYLENNCIGRIKIRSNWNGY 89 Query: 224 CDIQFVYTHLQYRHKGIGHDLVSFAVDHAFKKHHATSVQLSVKSKREKDIAFYEKLGFK 282 I+ + YR KG+G L+ A++ A K++H + L + FY K F Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWA-KENHFCGLMLETQDINISACHFYAKHHFI 147
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 28.0 bits (62), Expect = 0.047 Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 4/59 (6%) Query: 39 VWEVVKEEAKKDGINIEFVEFQDY--TAPNNALSEGE--IDLNAFQHFAFLDQFKKDHN 93 +E +K K+ GI I VE +A N+ALS G LN F+H + Q+ H Sbjct: 82 AFEALKAINKQTGIEINNVEPSSNFESAYNSALSAGHKIWVLNGFKHQQSIKQYIDAHR 140
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.3 bits (138), Expect = 1e-12 Identities = 16/104 (15%), Positives = 43/104 (41%), Gaps = 5/104 (4%) Query: 3 KKQLIENSLIQLMEEKRFREITIKMLCNKAGINRSTFYAYFEDKYALLDSMIDSHISHLE 62 ++ +++ +L +L ++ ++ + AG+ R Y +F+DK L + + S++ Sbjct: 13 RQHILDVAL-RLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 63 SILNNDLQDLHLQKDKKSSIEKYLEHIFQYIYE--HRQFFRVLL 104 + D S + + L H+ + R+ ++ Sbjct: 72 ELELEYQAKFP--GDPLSVLREILIHVLESTVTEERRRLLMEII 113
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 72.6 bits (178), Expect = 4e-17 Identities = 34/167 (20%), Positives = 61/167 (36%), Gaps = 19/167 (11%) Query: 58 FNKTVGDKLSK-DDKLGTV----AGAGQDGNPTKIDIKMPQDGTIVKKQA-TENGFVGAG 111 F + DKL + D +G + A + I+ P + + + TE G V Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQ--ASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 112 TPI-AYAYDMNQLFVTANIKETELDGIKKGQEVDVYVDGYKDTT---LSGEVEQIGLATA 167 + + + L VTA ++ ++ I GQ + V+ + T L G+V+ I L Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413 Query: 168 SSFSLLPSSNGNANFTKVTQVVPVKIKLSKDKSLDILPGMNVTVRIH 214 V + + +K++ + GM VT I Sbjct: 414 ED-------QRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIK 453
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 138 bits (349), Expect = 2e-37 Identities = 99/412 (24%), Positives = 188/412 (45%), Gaps = 18/412 (4%) Query: 100 KIIIALMAGMFVAILNQTLINVALPVMINDFSISTSTAQWLTTGFMLVNGILVPVSAYLI 159 +I+I L F ++LN+ ++NV+LP + NDF+ ++ W+ T FML I V L Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 160 QKFTYRQLFMFAMIAFTIGSVICAIS-TNFPVMMTGRVIQAVGAGILMPLGTNVFMTVFP 218 + ++L +F +I GSVI + + F +++ R IQ GA L V P Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 219 PEKRGAAMGMMGIAFILAPAIGPTLTGWVIQNYHWNVMFYGMSVVGILAIIIGFFWFKIY 278 E RG A G++G + +GP + G + HW+ + ++ ++ II F K+ Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL----LIPMITIITVPFLMKLL 189 Query: 279 QPISNPK--LDVPGVIFSSLGFGSLLYGFSEAGNKGWDSGIVITTMIIGLLFVALFVYRE 336 + K D+ G+I S+G + + I+ +I+ +L +FV Sbjct: 190 KKEVRIKGHFDIKGIILMSVGIVFFMLFTTSY---------SISFLIVSVLSFLIFVKHI 240 Query: 337 ISMKAPMMDLRALKYTGFSFTLLINVIVTMSLFGGMLLLPVYLQSIRGFSPLDSG-LLLL 395 + P +D K F +L I+ ++ G + ++P ++ + S + G +++ Sbjct: 241 RKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIF 300 Query: 396 PGSLLMGLMGPISGRLLDKFGIKPIAIFGLLIMTYATWELTKLSMDTSYSTILGIYVLRS 455 PG++ + + G I G L+D+ G + G+ ++ + + L TS+ + I V Sbjct: 301 PGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIII-VFVL 359 Query: 456 FGMSFIMMPIMTAGMNALPQRMIPHGNAISNTVRQLAGSIGTAVLVTIMTQQ 507 G+SF I T ++L Q+ G ++ N L+ G A++ +++ Sbjct: 360 GGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 111 bits (279), Expect = 2e-31 Identities = 79/253 (31%), Positives = 127/253 (50%), Gaps = 13/253 (5%) Query: 43 LRGKVALITGGDSGIGRAVAICYAKEGADVAIGYYNEHEDAKDTVARLESLGVKAKAYAF 102 + GK+A ITG GIG AVA A +GA +A YN E + V+ L++ A+A+ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPA 64 Query: 103 DLKSEEQCNQLVADVTSEFGSLNILVNNGGVQYPQESLLDISSEQIKETFETNIFGMMYV 162 D++ +++ A + E G ++ILVN GV P + +S E+ + TF N G+ Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPG-LIHSLSDEEWEATFSVNSTGVFNA 123 Query: 163 TKAALPHL--SKGDAIVNTSSVTAYRGSKTLIDYSATKGAITSFTRSLSQNIAEEGIRVN 220 +++ ++ + +IV S A ++ Y+++K A FT+ L +AE IR N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 221 AVAPGPIYT----PLIPATFPAEKVENHGQET-----ALERRGQPSEIAPAYVFLASDDA 271 V+PG T L AE+V ET L++ +PS+IA A +FL S A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 272 SYITGETIHINGG 284 +IT + ++GG Sbjct: 244 GHITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 49.4 bits (118), Expect = 1e-08 Identities = 56/356 (15%), Positives = 125/356 (35%), Gaps = 20/356 (5%) Query: 18 IVILFLMEFARGMYILSFLPVLPTL------SNVTVGIISACITLHFVSDALTNFGIGFL 71 ++++ + I +PVLP L SN + L+ + +G L Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 72 LKRYGTKKVLNAGFFIAAAGLALIIFDRNPATLVAAAILLGIAVSPIWVI---MLSSVED 128 R+G + VL AA A++ L I+ GI + V + + Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDG 126 Query: 129 NKRSKHMGYVYFAWLVGMMSGMIIMNLIIKVHPVQYIFLMPLFVLCAWMLYLFVHVEVSF 188 ++R++H G++ + GM++G ++ L+ P F ++ F+ E Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHK 186 Query: 189 IEKKSLKTQYKHIKHVMSRHLVLFPGILFQGIAIGMLVP------ILPSYAVHSLNVSTL 242 E++ L+ + + + + M + + + + Sbjct: 187 GERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDAT 246 Query: 243 EYTYLLIAGGAGCTVSMLFISKFMDDISNIYAHI-VILAGFFIFGISILLMTQVTNYMIV 301 L A G + L + ++ ++ G G +L+ T + Sbjct: 247 TIGISLAAFGI---LHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMA 303 Query: 302 LGAALVIGLFYGLLLPGWNAFMASQVDVALKEESWGVFNSLQGIGTMLGPIIGGLI 357 +++ G+ +P A ++ QVD + + G +L + +++GP++ I Sbjct: 304 FPIMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAI 358 Score = 39.8 bits (93), Expect = 1e-05 Identities = 35/182 (19%), Positives = 70/182 (38%), Gaps = 11/182 (6%) Query: 210 VLFPGILFQGIAIGMLVPILPSY--AVHSLNVSTLEYTYLLIAGGAGCTVSMLFISKFMD 267 V+ + + IG+++P+LP + N T Y LL A + + + Sbjct: 9 VILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILL----ALYALMQFACAPVLG 64 Query: 268 DISNIYAH-IVILAGFFIFGISILLMTQVTNYMIVLGAALVIGLFYGLLLPGWNAFMASQ 326 +S+ + V+L + +M ++ VL ++ G A++A Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMA-TAPFLWVLYIGRIVAGITGATGAVAGAYIADI 123 Query: 327 VDVALKEESWGVFNSLQGIGTMLGPIIGGLITELFRDTDYTLFTSAIVFIGLAFFYLFYF 386 D + +G ++ G G + GP++GGL+ + + F +A GL F + Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGLMGGF---SPHAPFFAAAALNGLNFLTGCFL 180 Query: 387 YR 388 Sbjct: 181 LP 182
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 220 bits (563), Expect = 1e-66 Identities = 118/457 (25%), Positives = 209/457 (45%), Gaps = 68/457 (14%) Query: 15 IISHPDAGKTTLTEKLLLFGGAIREAGTVKGKKTGKFATSDWMEVEKQRGISVTSSVMQF 74 +++H DAGKTTLTE LL GAI E G+V T +D +E+QRGI++ + + F Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTT----RTDNTLLERQRGITIQTGITSF 63 Query: 75 DYDNFKINILDTPGHEDFSEDTYRTLMAVDSAVMVIDCAKGIEPQTLKLFKVCKMRGIPI 134 ++N K+NI+DTPGH DF + YR+L +D A+++I G++ QT LF + GIP Sbjct: 64 QWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT 123 Query: 135 FTFINKLDRVGKEPFELLEEIEKTLEIETYPMNWPIGMGQSFFGIIDRKTKTIEPFRDEE 194 FINK+D+ G + + ++I++ L E +I +K Sbjct: 124 IFFINKIDQNGIDLSTVYQDIKEKLSAEI---------------VIKQKV---------- 158 Query: 195 NVLHLNEDYELQESHAITSDSAYEQAIE---ELMLVDEAGETFDKEKLMT--------GD 243 E Y T ++ IE +L+ +G++ + +L Sbjct: 159 ------ELYPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCS 212 Query: 244 LTPVFFGSALANFGVQNFLNAYVDHAPMPSGRKTESGEEISPFDESFSGFIFKIQANMNP 303 L PV+ GSA N G+ N + + T G+ G +FKI Sbjct: 213 LFPVYHGSAKNNIGIDNLIEVITNKFYSS----THRGQ------SELCGKVFKI---EYS 259 Query: 304 QHRDRIAFMRIVSGAFERGMDIKMTRTDKKMKISRSTSFMADDTQTVNHAVSGDIIGLYD 363 + R R+A++R+ SG ++++ +K KI+ + + + ++ A SG+I+ L + Sbjct: 260 EKRQRLAYIRLYSGVLHLRDSVRISEKEKI-KITEMYTSINGELCKIDKAYSGEIVILQN 318 Query: 364 SG---NFQIGDTLVGGNQKFQFEKLPQFTPEIFMKVSPKNVMKQKHFHKGIEQLVQEG-A 419 N +GDT + ++ LP + V P +++ + ++ Sbjct: 319 EFLKLNSVLGDTKLLPQRERIENPLPL----LQTTVEPSKPQQREMLLDALLEISDSDPL 374 Query: 420 IQLYRTLHTNQIILGAVGQLQFEVFEHRMNNEYNVDV 456 ++ Y T++IIL +G++Q EV + +Y+V++ Sbjct: 375 LRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEI 411
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 60.8 bits (147), Expect = 3e-12 Identities = 48/259 (18%), Positives = 89/259 (34%), Gaps = 57/259 (22%) Query: 140 FQQKDKPQEKAALSQTEQIAQHK-----DTVVTVTNLQKASTDEPIDA--QASEKAPEET 192 QQ K Q+ L EQ + +T+ +T+ +AP T Sbjct: 46 KQQTPKIQKGGNLKPLEQREHANVILPNNDRHQITD----TTNGHYAPVTYIQVEAPTGT 101 Query: 193 GIGSGVIYKIDEKYAYIVTNHHVVAKAPTIEVT--------------QGKLKEKATLIGK 238 I SGV+ D ++TN HVV G + + Sbjct: 102 FIASGVVVGKDT----LLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAE-QITKY 156 Query: 239 DIWTDIAVIRI----PNGNLKSTVT---FGDSSKLEVGEHVLALGSPLGK-IFAGSVTSG 290 D+A+++ N ++ V ++++ +V +++ G P K + + G Sbjct: 157 SGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKG 216 Query: 291 IISGLERTVPVDIDGDNEYDWSMDVIQTDAAINPGNSGGALFNDKGEMIGLNSLKITMNG 350 I+ L+ +Q D + GNSG +FN+K E+IG++ + Sbjct: 217 KITYLKGEA----------------MQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEF 260 Query: 351 VEGIAFSIPANAVKKNIKA 369 + V+ +K Sbjct: 261 NGAVFI---NENVRNFLKQ 276
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 31.6 bits (71), Expect = 0.007 Identities = 25/153 (16%), Positives = 52/153 (33%), Gaps = 15/153 (9%) Query: 154 DEQYIITMEIDVNTIGAVIDSLQKDTTVTIK-----DFDGQTIFQSINPHRNSISASEKF 208 + + + ++ N G SL K V+I F + I S+ + Sbjct: 54 EPSVVSSQILNPNETGTFSQSLTKSKEVSINVNFSVGFTSEFIQASVEYGFGITIGEQNT 113 Query: 209 FKVPWEITLTTNRNVYYDVYSSALIYTLIASL--------IFLTLHLLYISYRNKRANEK 260 + T N VYY VY++ Y I L +++S + + Sbjct: 114 IERSVSTTAGPNEYVYYKVYATYRKYQAIRISHGNISDDGSIYKLTGIWLSKTSADSLGN 173 Query: 261 VLED--INTQRKEIIGLLAANTAHEIKNPLTSI 291 + + I T + ++ + + + EI + + Sbjct: 174 IDQGSLIETGERCVLTVPSTDIEKEILDLAAAT 206
>PF03309#Bvg accessory factor Length = 271 Score = 30.5 bits (69), Expect = 0.008 Identities = 9/37 (24%), Positives = 20/37 (54%), Gaps = 3/37 (8%) Query: 1 MILAADIGGTTCKLGILDSN---LNIIKKWEIVTNKD 34 M+LA D+ T +G++ + ++++W I T + Sbjct: 1 MLLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPE 37
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.1 bits (65), Expect = 0.010 Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 5/78 (6%) Query: 163 VAYIDNMPAGKIEAIIE-DKTVEIDDFYVIETYRKRGIGSRLQEAVYDLAHGKQVFLI-- 219 + Y++N G+I+ + I+D V + YRK+G+G+ L + A + Sbjct: 69 LYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLML 128 Query: 220 --ADGNDTARDMYQRQGY 235 D N +A Y + + Sbjct: 129 ETQDINISACHFYAKHHF 146
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 33.9 bits (78), Expect = 0.001 Identities = 45/205 (21%), Positives = 69/205 (33%), Gaps = 58/205 (28%) Query: 1 MKTLINNVNILDVERGAYMNHRSVVIEDNRIISF------DDTDNADII-------IDGE 47 + T+I N ILD G + ++D RI + D II I GE Sbjct: 68 VDTVITNALILDHW-GIV--KADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGE 124 Query: 48 DRYLLPGMIDSHVHMVFEFKPVESRLATPFSYNFYQAMDYAKSTIDAGITTVRDALGADI 107 + + G +DSH+H + P Q ++ A + +G+T + Sbjct: 125 GKIVTAGGMDSHIHFI-----------CP------QQIEEA---LMSGLTCM-------- 156 Query: 108 GYKKAIEDGLFIGPRTVCSINALTITGGHGDGYQYSGNSIDIIPTDYPGMPNGICDGVEE 167 + G GP A T T G + + D P + G Sbjct: 157 -----LGGG--TGPAH--GTLATTCTPGPWHIARMIE-AADAFPMNLAFAGKGNASLPGA 206 Query: 168 VRKKAREMLRAGADVLKVHATGGVT 192 + EM+ GA LK+H G T Sbjct: 207 L----VEMVLGGATSLKLHEDWGTT 227
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.016 Identities = 9/26 (34%), Positives = 12/26 (46%), Gaps = 1/26 (3%) Query: 28 FKGEICAII-GKNGAGKSTFFKLLAG 52 K + ++ G G GKST L G Sbjct: 593 CKFDYSVVLEGTGGIGKSTLINTLVG 618
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.9 bits (223), Expect = 5e-23 Identities = 33/112 (29%), Positives = 56/112 (50%), Gaps = 2/112 (1%) Query: 2 AHILIIEDDRDIADLLALTLSGH-YDVTLAHDGKEGYMYIKEQAFDLILLDLMMPYMNGE 60 A IL+ +DD I +L LS YDV + + + +I DL++ D++MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 61 TLLGEIK-HHTNTKVIIITAKHELEHKVNLLTLGADDYITKPFYQEEVLARV 111 LL IK + V++++A++ + GA DY+ KPF E++ + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 26.1 bits (57), Expect = 0.038 Identities = 11/79 (13%), Positives = 34/79 (43%), Gaps = 7/79 (8%) Query: 13 LIVILTLVYSSIHLYGNDHILWSIVYCLLIFIMLMTFFITTS-------DEEEINEQLDQ 65 L +L ++S + +G I+ + + +++ + + + + + + E+L Sbjct: 340 LFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGD 399 Query: 66 EVKRLNMPRERLYQVTGYN 84 + +R++ LY+ N Sbjct: 400 DKQRISQEMMALYKAEKVN 418
>PF04647#Accessory gene regulator B Length = 212 Score = 25.9 bits (57), Expect = 0.040 Identities = 10/52 (19%), Positives = 19/52 (36%) Query: 45 AKSYGLILLVELILIIAAPLIKIPIPLLTVLMIIALALVIVLLPLSLKLVAE 96 + Y L L++ I I ++I +A + LL L + + Sbjct: 74 CEKYYRCTLTSLLVFNVLAYIAHLIDPAYFQLLILIAFITSLLALLFLVPVD 125
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 49.2 bits (117), Expect = 8e-10 Identities = 23/109 (21%), Positives = 43/109 (39%), Gaps = 7/109 (6%) Query: 54 YLKTAFTDEKVERELSNPHSFFYFIFHEEQLAGYLKLNIKDAQTEPFDEHHLEIERIYIL 113 Y K D+ + + + E G +K+ ++ + IE I + Sbjct: 46 YFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIR------SNWNGY-ALIEDIAVA 98 Query: 114 KQFQKHGLGQSLYQHALQKARALSCEHIWLGVWEKNTNAIDFYQKMGFT 162 K ++K G+G +L A++ A+ + L + N +A FY K F Sbjct: 99 KDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 165 bits (418), Expect = 2e-55 Identities = 67/148 (45%), Positives = 99/148 (66%) Query: 2 AKKSNDNKVVTALNQQVANWTVLYTKIHNYHWYVKGPHFFSLHMKFEEFYNEASTYIDEL 61 K+N V +LN Q++NW +LY+K+H +HWYVKGPHFF+LH KFEE Y+ A+ +D + Sbjct: 5 NAKTNQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTI 64 Query: 62 AERILAIQGHPIATLKESLELSVVKEAKKDLAAEDMVKDLSKDFDKIIKQLEEGKAAAEE 121 AER+LAI G P+AT+KE E + + + + +A +MV+ L D+ +I + + AEE Sbjct: 65 AERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLAEE 124 Query: 122 AGDEMTADMFLGMITNLEKHNWMLKSFL 149 D TAD+F+G+I +EK WML S+L Sbjct: 125 NQDNATADLFVGLIEEVEKQVWMLSSYL 152
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.1 bits (99), Expect = 3e-06 Identities = 63/371 (16%), Positives = 116/371 (31%), Gaps = 55/371 (14%) Query: 54 VFAAGYALMQVP----AGIMAEKFGPKKMLTFALVWWSAFTILTGVVKNHGLLYTMRFLF 109 + A YALMQ G ++++FG + +L +L + + +LY R + Sbjct: 47 ILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVA 106 Query: 110 GIGEGPMYPSNAVF--------NTYWFAKSEKGRASSALLAGSYFGPVIAPFVTIAIYQA 161 GI + A F G S+ G GPV+ + Sbjct: 107 GITGATGAVAGAYIADITDGDERARHF-----GFMSACFGFGMVAGPVLGGLMG-----G 156 Query: 162 FGWEAVFFIFGAIGIVIAAIWAIIAKDLPEHHKMVNEAEKAYIMENRDVVQTDKKSAPWG 221 F A FF A+ + + LPE HK + + S W Sbjct: 157 FSPHAPFFAAAALNG-LNFLTGCFL--LPESHKGERRPLRREALN-------PLASFRWA 206 Query: 222 IFFKRFSFFAIAGQYFVVQFVITLFLIWLPTYLQEEYHVVLKDMKF-LAAAPWLMMFILI 280 + + F++ L + V+ + +F A + Sbjct: 207 RGMTVVAA-----------LMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAF 255 Query: 281 MAGGTISDAIISRGYSRFRARALIAIFGFIVFAVSLFLSVQTNDM-MMNLIYLSLCLGGV 339 +++ A+I+ + + G I L M I + L GG+ Sbjct: 256 GILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGI 315 Query: 340 GLSMGMSWASATDLGRNFSGTVSGWMNLWGNVGAFLSPMLGGYLVQHY-----GW----D 390 G+ + S + G + G + ++ + + P+L + GW Sbjct: 316 GMPALQAMLS-RQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAG 374 Query: 391 TTFYLMIIPAV 401 YL+ +PA+ Sbjct: 375 AALYLLCLPAL 385
>PF07472#Fucose-binding lectin II Length = 245 Score = 27.3 bits (60), Expect = 0.028 Identities = 32/134 (23%), Positives = 49/134 (36%), Gaps = 14/134 (10%) Query: 46 SGEVDAVKAIKEIVPG---GVDRSFEVAGVTPTFVQA--IDATRPRGTMVIVSIFAGDIS 100 +G+V A PG G F V V F +A GT G + Sbjct: 78 AGQVIACTVTWAGAPGVLPGAAAKFGVGAVVNYFSKATPQPEPTQPGTTTGGGERDGIFN 137 Query: 101 WPPLQLTNTGVKITSTIAYSRASYQQTIDLMGSGQIDTESTITGEIELDDIVEHGFEKLT 160 PP N +T A +S QQTI++ +T G D + + + Sbjct: 138 LPP----NIAFGVT---ALVNSSAQQTIEVYVDDNPKPAATFQGAGTQDANL--NTQIVN 188 Query: 161 NDKSQVKILVKLNG 174 + K +V+++V NG Sbjct: 189 SGKGKVRVVVTANG 202
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.5 bits (71), Expect = 0.001 Identities = 28/134 (20%), Positives = 47/134 (35%), Gaps = 28/134 (20%) Query: 18 QKAAIKEIGNKDMLVTLSEEEIAQNVDDGVLCVCQIDERIVAFRSMHIPVDDYLGKYIAL 77 K K+ + DM V+ EEE + ++ + I + Sbjct: 43 SKPYFKQYEDDDMDVSYVEEE------GKAAFLYYLENNCIG--------------RIKI 82 Query: 78 DPSYRDQLIYSDITVVHPDYRGRGLQKIL----GEWLFQAIDDKFKIIMATVHPDNIASI 133 ++ + DI V DYR +G+ L EW A ++ F +M NI++ Sbjct: 83 RSNWNGYALIEDI-AVAKDYRKKGVGTALLHKAIEW---AKENHFCGLMLETQDINISAC 138 Query: 134 KDKFHHGMKIVALD 147 H I A+D Sbjct: 139 HFYAKHHFIIGAVD 152
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 27.6 bits (61), Expect = 0.016 Identities = 17/72 (23%), Positives = 29/72 (40%), Gaps = 2/72 (2%) Query: 2 IKLEQSIFKTASQVEHVLNAILLKRFGITFAEFL--ILYKVYKDSNSSVTDIQDDIQYKM 59 ++L F TA +V V+NA R+G AE V K + +T + +I+ Sbjct: 195 LQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRVADLTRLMAEIENLT 254 Query: 60 DSASKKTKKLRD 71 K + + Sbjct: 255 VETDTPAKVVIN 266
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 28.2 bits (63), Expect = 0.049 Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 11/67 (16%) Query: 89 IIGLMIASMISLIFNFMGF-------PFLKNTVPIILAVVLGYLGFQVGIQKRGEILSFL 141 II + +++ S F F+ F++ P +A++L YL QK ILS L Sbjct: 104 IINNLGSALQSRPFEFVRRADPANILNFIQQEHPQTIALILSYLD----PQKASFILSSL 159 Query: 142 PERFQPN 148 P Q N Sbjct: 160 PTEVQTN 166
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.024 Identities = 17/89 (19%), Positives = 36/89 (40%), Gaps = 4/89 (4%) Query: 80 RVLGGGIVPGSLILIGGDPGIGKSTLLLQVCAMLSQ-NHPVLYISGEESVRQTKLRADRL 138 RV+ G +++ G GIGKSTL+ + + + +G++S Q + Sbjct: 587 RVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQ--IAGIVA 644 Query: 139 LEDAGELDVYAETNLQIIHETVKRSKPKF 167 E E+ + + + + K ++ Sbjct: 645 YE-LSEMTAFRRADAEAVKAFFSSRKDRY 672
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 43.7 bits (103), Expect = 1e-06 Identities = 38/177 (21%), Positives = 61/177 (34%), Gaps = 39/177 (22%) Query: 247 VIGQSDAVSSISKAVRR-ARAGLKDPKRPIGSFIFLGPTGVGKTELAKALAEAMFGEEDA 305 ++G+S A+ I + + R + L + + G +G GK +A+AL + Sbjct: 139 LVGRSAAMQEIYRVLARLMQTDL--------TLMITGESGTGKELVARALHDYGKRRNGP 190 Query: 306 MIRVDM---------SEFM--EKHSVSRMVGSPPGYVGHDDGGQLTEKVRRKPYSVILFD 354 + ++M SE EK + + G +GG L D Sbjct: 191 FVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTL------------FLD 238 Query: 355 EIEKAHPDVFNILLQVLDDG---RLTDSKGRTVDFRNTVIIMTSNVG-AQEIKDNKF 407 EI D LL+VL G + D R I+ +N Q I F Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IVAATNKDLKQSINQGLF 292
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.1 bits (73), Expect = 0.002 Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 11/87 (12%) Query: 133 ARSQVVKLLGSPEMAGKDANASKSQNTPTLDELARDLTVIAKDG-TLDPVIGRSAEITRV 191 A + K E+ G A L E R + + D P++GRSA + + Sbjct: 98 AYDYLPKPFDLTELIGIIGRA--------LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEI 149 Query: 192 IEVLSRRTKNN-PVLI-GEPGVGKTAI 216 VL+R + + ++I GE G GK + Sbjct: 150 YRVLARLMQTDLTLMITGESGTGKELV 176