>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 34.0 bits (78), Expect = 9e-04 Identities = 38/242 (15%), Positives = 73/242 (30%), Gaps = 64/242 (26%) Query: 222 NADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGKISKTA 281 AD++ S K+ +V ++ +G + + Y + DY P +S+ Sbjct: 57 RADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQ---DLVDYSP-----VSEKH 108 Query: 282 DKKDYNVMELLKAVAQQSDNVATNILGYYL-----CNQY------------------NQA 318 V EL A SDN A N+L + + N+A Sbjct: 109 LADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEA 168 Query: 319 FQSEIRALAGVDWDMEKRLLSSHAAANLMEAIYY-------QKGQIISYLSQTAFDDQRI 371 + R D + + A + + + Q++ ++ I Sbjct: 169 LPGDAR-----DTT------TPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLI 217 Query: 372 SKNISVP----VAHKIGD-AYDYKHDVAIVYGDN--PFILSVFT------DKASYDDITA 418 +P +A K G + VA++ +N I+ ++ I Sbjct: 218 RS--VLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAG 275 Query: 419 IA 420 I Sbjct: 276 IG 277
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 36.0 bits (83), Expect = 5e-04 Identities = 22/88 (25%), Positives = 34/88 (38%), Gaps = 18/88 (20%) Query: 216 ARIPAGVLLEGPPGTGKTLLAKAV---AGEAGVPFFS-----ISGSDFVEMFVGV----- 262 + +++ G GTGK L+A+A+ PF + I G Sbjct: 157 MQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAF 216 Query: 263 -GASRVRS-LFEDAKKAERAIIFIDEID 288 GA + FE +AE +F+DEI Sbjct: 217 TGAQTRSTGRFE---QAEGGTLFLDEIG 241
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 30.8 bits (69), Expect = 0.011 Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 242 GGQVMETVGIENMIGTLYT--EGPKLMAQVEEHTKSYDVDIIKAQ 284 G M+ G+E +GTL E P + A +E+ + +DI+K Q Sbjct: 205 NGSAMQIRGVEKALGTLKITHENPNVEANYDENAAALSIDIVKKQ 249
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 30.8 bits (69), Expect = 0.003 Identities = 8/21 (38%), Positives = 14/21 (66%) Query: 15 NVSVEELAKKLGVSKTTIYRY 35 + S+ E+AK GV++ IY + Sbjct: 31 STSLGEIAKAAGVTRGAIYWH 51
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 27.5 bits (61), Expect = 0.004 Identities = 7/20 (35%), Positives = 14/20 (70%) Query: 18 QQAVADSIGIDRSTFYRKMK 37 Q AD +G++R+T +K++ Sbjct: 452 QIKAADLLGLNRNTLRKKIR 471
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 26.4 bits (58), Expect = 0.033 Identities = 8/31 (25%), Positives = 16/31 (51%), Gaps = 3/31 (9%) Query: 18 ISPFEIEDIQ---KWIHQDNMPIDVVNLALR 45 I P+ + D W+ + +P V+++ LR Sbjct: 54 IVPYGVADTINYRLWVSEPPLPDSVIDVGLR 84
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 29.2 bits (65), Expect = 0.020 Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 3/42 (7%) Query: 7 KKGDKVWVEGIISSSFSNGG---VHVNHAGIDAFYNLERTKI 45 +K VW I +S ++GG ++ AG+DA+ N E I Sbjct: 1020 EKPTNVWANAIGGTSLNSGGNASLYGTSAGVDAYLNGEVEAI 1061
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 34.4 bits (78), Expect = 0.003 Identities = 46/209 (22%), Positives = 91/209 (43%), Gaps = 31/209 (14%) Query: 456 RESDETKK-LKKEQEGLVESNKKLRDSVKEGVQERKKNLESVKESTAA------------ 502 +E +E KK L+KE+E ++ K +D ++ +ER KN +++ T A Sbjct: 139 KELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKN 198 Query: 503 -----HQKLADEIVKLAAKENKTAGEKQNLKNKIDQLNG----------SIDGLNLAYDK 547 Q+ +E+ ++ E+ + N +I++LN + D +++ DK Sbjct: 199 LSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEEAVRQRAKDKISIKTDK 258 Query: 548 NSNSLSHNADQIKARISAMEAESVWQTAQ---QNLLSIEQKRSEVSKKLAENAELRKKWN 604 + S N+ ++ SA V +T + Q +L I QK + S L E ++ Sbjct: 259 SQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHE 318 Query: 605 EEANVSDSARKEKIAELTEEEGKLKNMQT 633 + + + +K + A+ E K +N+ T Sbjct: 319 VSSVIEEELKKREEAKRQRELIKQENLNT 347
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 30.0 bits (67), Expect = 0.033 Identities = 29/142 (20%), Positives = 49/142 (34%), Gaps = 17/142 (11%) Query: 548 LNAEIIGTDGKTRYNKNLLVGDPSRTKSYDEDFIEIEANDG-GFKRGETYTISFSQTCEL 606 LN GT ++ + + + + + +FI+ G G GE TI S Sbjct: 63 LNPNETGTFSQSLTKSKEVSINVNFSVGFTSEFIQASVEYGFGITIGEQNTIERS----- 117 Query: 607 LKKVAITLTQPHNKGLKLVLTSTKAKMEAQTFDLTKDIEVISVYPLSYRAVLTGDWYKSK 666 ++ T N+ + + +T K +A + S+Y LTG W Sbjct: 118 -----VSTTAGPNEYVYYKVYATYRKYQAIRISHGNISDDGSIY------KLTGIWLSKT 166 Query: 667 QMDFNAAEVQDLALEMSYRDVV 688 D Q +E R V+ Sbjct: 167 SADSLGNIDQGSLIETGERCVL 188
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 65.5 bits (159), Expect = 9e-15 Identities = 28/58 (48%), Positives = 40/58 (68%) Query: 1 MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGDGKNRYADLIYQGGP 58 M+ETI V K MT EW SD+IL + ++ +E+DTG++KFGDGKN+++ L Y P Sbjct: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKP 58
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.1 bits (86), Expect = 2e-04 Identities = 31/200 (15%), Positives = 67/200 (33%), Gaps = 19/200 (9%) Query: 112 RDHISTEIVETADGIAKRISDDTGQKLALINETIKGIKREYQDADERLSA--SYQAGIEG 169 R I + +E ++ D+ + E + R E+ S + + E Sbjct: 152 RYQILSRSIELNKLPELKLPDEPYFQNVSEEE----VLRLTSLIKEQFSTWQNQKYQKEL 207 Query: 170 LKAQLANDKIGLQAEI--KLSAQGLSQKYDDELRKLYAKITTTSSGTTEAYENKLEGLRA 227 + +++ + A I + + + D+ L K + ENK Sbjct: 208 NLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHK-QAIAKHAVLEQENKYVEAVN 266 Query: 228 EFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIRDRTGAISRVQQDLASYQRRLQDAE 287 E R + ++ES+I K Q + EI D+ + + ++ L E Sbjct: 267 EL-RVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK---LRQTTDNIGLLTLELAKNE 322 Query: 288 KN------YSSLTQTVKGLQ 301 + + ++ V+ L+ Sbjct: 323 ERQQASVIRAPVSVKVQQLK 342
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 90.9 bits (225), Expect = 1e-22 Identities = 44/123 (35%), Positives = 62/123 (50%), Gaps = 8/123 (6%) Query: 23 SLTAAQAILESGWGKYA-------PHNALFGIKADSSWTGKSFNTKTQEEYQPGVVTDIV 75 L AQA LESGWG+ P LFG+KA +W G T E Y+ G + Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230 Query: 76 DRFRAYDSWDESILDHGQFLVDNPRYKSVVGETDYKKACHAIKAAGYATASDYAELLIQL 135 +FR Y S+ E++ D+ L NPRY +V ++ A++ AGYAT YA L + Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290 Query: 136 IEE 138 I++ Sbjct: 291 IQQ 293
>PF05043#Transcriptional activator Length = 493 Score = 29.5 bits (66), Expect = 0.035 Identities = 22/124 (17%), Positives = 44/124 (35%), Gaps = 28/124 (22%) Query: 258 NLIWKRKEYQI--------------------AKALASELYHNFKLHLDDIEVGMI----- 292 NL + + + + +A + + LD+ V + Sbjct: 207 NLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYF 266 Query: 293 -AMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHFTHKKDLLRQLTRHCKAL 351 M + + E+ + DFIDQ+ ++YQ+ +K +L+ L H A Sbjct: 267 QKMFFIDESLFMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEIENKDNLIWHL--HNTAH 324 Query: 352 VYRK 355 +YR+ Sbjct: 325 LYRQ 328
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 67.0 bits (163), Expect = 3e-14 Identities = 64/327 (19%), Positives = 123/327 (37%), Gaps = 30/327 (9%) Query: 52 KEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQKVKELNDKV 111 + ++K + +L L G N ++K E + L + Sbjct: 238 MNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEK 297 Query: 112 NSETQGKQELQNQLEKEKEELET---LKKELEAEKAKGTGETEKLQKEIEAKNAMISDLQ 168 Q L + + +L+ KK+LEAE K + + + ++ + + Sbjct: 298 ADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASR 357 Query: 169 KQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKAQIEKLKHCQD 228 + ++ + Q+ E + A + L+ L+ + +++K +E+ +++ L+ + Sbjct: 358 EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALE--KL 415 Query: 229 TPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPGPKPEPKPEPKP--GPKPEPKPEP 286 + E + + K E + + + E K + K + K P+ KP Sbjct: 416 NKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGN 475 Query: 287 KPGPKPGPKPEPKPGPKPEPKPEPKPEPKPEAKKPEQPKPMTKPGAKKPEQSLPSTGDIR 346 K P G P+ P P K+ ++ LPSTG+ Sbjct: 476 KAVPGKGQAPQAGTKPNQNKAP-----------------------MKETKRQLPSTGETA 512 Query: 347 NPFFTPAAIAIMIAAGTIAIPKRKEED 373 NPFFT AA+ +M AG A+ KRKEE+ Sbjct: 513 NPFFTAAALTVMATAGVAAVVKRKEEN 539 Score = 42.4 bits (99), Expect = 2e-06 Identities = 25/165 (15%), Positives = 51/165 (30%) Query: 61 ELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQKVKELNDKVNSETQGKQE 120 E +++ + +K + L+ + + + +G Sbjct: 110 EKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 169 Query: 121 LQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAKNAMISDLQKQLEETKQRVQE 180 + + LE K LEA +A+ E A +A I L+ + R + Sbjct: 170 FSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKAD 229 Query: 181 FEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKAQIEKLKH 225 E + M K+ E A L+ +L+ +E + Sbjct: 230 LEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN 274 Score = 41.6 bits (97), Expect = 4e-06 Identities = 31/194 (15%), Positives = 63/194 (32%) Query: 31 TTLAGQTEVRADNILRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLR 90 L T + R E V++ A++ + E + ++ L + + Sbjct: 31 AGLVVNTNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDEL 90 Query: 91 EQIETELKNSEQKVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGET 150 + + K +K + + S+ Q + + LEK E A+ E Sbjct: 91 TEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEK 150 Query: 151 EKLQKEIEAKNAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQ 210 L + +++ EAE L A +A+L+ L + Sbjct: 151 AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 210 Query: 211 KEIEDLKAQIEKLK 224 +I+ L+A+ L Sbjct: 211 AKIKTLEAEKAALA 224
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 58.8 bits (142), Expect = 4e-12 Identities = 51/253 (20%), Positives = 99/253 (39%), Gaps = 28/253 (11%) Query: 32 DKERIVATSVAVVDICDRLSLDLVGVCDSKLYQL----PKRYDAVKRIGLPMNPDMEVIA 87 D RIVA V++ L + GV D+ Y+L P D+V +GL P++E++ Sbjct: 34 DPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLT 93 Query: 88 SLKPTWILSPNSLQNDLEPKYQQLDTEYGFLNLTSLEG------MYQSIDDLGDLFDRKK 141 +KP++++ P + L +G +S+ ++ DL + + Sbjct: 94 EMKPSFMV----WSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQS 149 Query: 142 EAKRLRADYEEFYRAFKKKHKGQ-KKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENV 200 A+ A YE+F R+ K + + +P +L + P L+ S +L+ G N Sbjct: 150 AAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNA 209 Query: 201 YHSEDKEFLSA--NPEDMLQQQPELILRTAHAI---PDKVKDMFDKEFAENDIWKHFEAV 255 + E + S + + + + + D KDM +W+ V Sbjct: 210 WQGETNFWGSTAVSIDRLAA------YKDVDVLCFDHDNSKDM--DALMATPLWQAMPFV 261 Query: 256 KSQQVYDLDNTLF 268 ++ + + F Sbjct: 262 RAGRFQRVPAVWF 274
>SECA#SecA protein signature. Length = 901 Score = 33.7 bits (77), Expect = 0.003 Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 7/80 (8%) Query: 276 RLLQGDV-----GSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQL--FPDL 328 L + + G GKT+ A+L Y G ++ + LA++ ++ L F L Sbjct: 93 VLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGL 152 Query: 329 SIALLTSGMKAAEKRAALSA 348 ++ + GM A KR A +A Sbjct: 153 TVGINLPGMPAPAKREAYAA 172
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 55.4 bits (133), Expect = 1e-11 Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Query: 78 RDLYGPLMT-------VYTRYQQDQRVFWLDKRHYSAFSGTDLDIRLRERGVTTLVLTGV 130 D +GP + + T + L K YSAF T+L +R+ G L++TG+ Sbjct: 92 TDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGI 151 Query: 131 LTDICVLHTAIDAYKLGYKLEIITSAVASNSTENHQWALNH 171 I L TA +A+ K + AVA S E HQ AL + Sbjct: 152 YAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMALEY 192
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 82.6 bits (204), Expect = 3e-18 Identities = 46/139 (33%), Positives = 65/139 (46%), Gaps = 18/139 (12%) Query: 464 IMGHVDHGKTTLLDTLRNSRVATGEAG------------------GITQHIGAYQIEEAG 505 ++ HVD GKTTL ++L + A E G GIT G + Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 506 KKITFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAI 565 K+ +DTPGH F + R SV D IL+++A DGV QT + + G+P I I Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 566 NKIDKPGANPERVISELAE 584 NKID+ G + V ++ E Sbjct: 128 NKIDQNGIDLSTVYQDIKE 146
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.3 bits (125), Expect = 8e-11 Identities = 15/65 (23%), Positives = 30/65 (46%) Query: 19 QESRRLTREAIEIALLSLLEKKPLGHITISELVARAGVSRNAFYRNYSSKEDILECLLTS 78 ++ + TR+ I L L ++ + ++ E+ AGV+R A Y ++ K D+ + Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 79 VIRRI 83 I Sbjct: 66 SESNI 70
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 50.4 bits (120), Expect = 2e-09 Identities = 37/221 (16%), Positives = 66/221 (29%), Gaps = 18/221 (8%) Query: 32 SPKPATITTQSKGYELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLT 91 P PAT + + T A+ +E++ E A A N+ ++K ++A Sbjct: 1027 PPAPATPSETT-----ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQ 1081 Query: 92 AISLKHNQEDVAIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPS 151 + + + ++ + E +E A+ K + K + P Sbjct: 1082 TNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQ---------VSPK 1132 Query: 152 TAQPETATPAAEKNIAPAPAA----PQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAP 207 Q ET P AE P PQ + T + +P + + Sbjct: 1133 QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTG 1192 Query: 208 ENPEPTPSPNPQPNPQPETNTPSPQPPATEQSENTAPAGQN 248 + P QP N+ S P + N Sbjct: 1193 NSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHN 1233 Score = 35.8 bits (82), Expect = 2e-04 Identities = 39/211 (18%), Positives = 59/211 (27%), Gaps = 27/211 (12%) Query: 39 TTQSKGYELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHN 98 T + QA V N E IA+ +A + A + K Sbjct: 991 TVDTTNITTPNNIQADVPSVPSN--NEEIARVDEAPVP-PPAPATPSETTETVAENSKQE 1047 Query: 99 QEDVAIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETA 158 + V A E + + +E A++A S + + + A+ + +T ETA Sbjct: 1048 SKTVEKNEQDATE--TTAQNREVAKEAKSNVKANTQTNEV-AQSGSETKETQTTETKETA 1104 Query: 159 TPAAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPT-PSPN 217 T E K P SP E E P Sbjct: 1105 TVEKE--------------------EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAE 1144 Query: 218 PQPNPQPETNTPSPQPPATEQSENTAPAGQN 248 P P N PQ ++ PA + Sbjct: 1145 PARENDPTVNIKEPQSQTNTTADTEQPAKET 1175
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 27.6 bits (61), Expect = 0.022 Identities = 19/89 (21%), Positives = 32/89 (35%), Gaps = 8/89 (8%) Query: 88 NHHRYVTFHRVAVLSDRTGQGIAQTFLQGLIE---GQHGPDFRIDTHEHNQVMRHIIEKL 144 N + Y +AV D +G+ L IE H ++T + N H K Sbjct: 85 NWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKH 144 Query: 145 GFVYCGKVPIDGERLAYQKIKKSHERAAY 173 F+ +D + Y ++E A + Sbjct: 145 HFIIGA---VD--TMLYSNFPTANEIAIF 168
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 89.1 bits (221), Expect = 6e-21 Identities = 42/173 (24%), Positives = 72/173 (41%), Gaps = 16/173 (9%) Query: 245 VIKLDDTSGGTIIDWQDTDDDSKYESHGMHVTGIAAGNGLKAAAAGERFLGIAPEAQVMF 304 +I + + D + D + HG HV G A +G+APEA ++ Sbjct: 63 IIGGRNFTDDDEGDPEIFKDYNG---HGTHVAGTIAATE-----NENGVVGVAPEADLLI 114 Query: 305 MRVFTHDLMGTGDPLFIKAIEDAVALGADVINLSLGSANGSQLNGNRALMAAIEKARQAG 364 ++V G D + I+ I A+ D+I++SLG L A++KA + Sbjct: 115 IKVLNKQGSGQYDWI-IQGIYYAIEQKVDIISMSLGGPEDV-----PELHEAVKKAVASQ 168 Query: 365 VSVVVAAGNERAFGSDHADPLVTN--PDYGLVGAPSAGRTPTSVASINNKVII 415 + V+ AAGNE + + VGA + R + ++ NN+V + Sbjct: 169 ILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNSNNEVDL 221 Score = 81.0 bits (200), Expect = 3e-18 Identities = 40/140 (28%), Positives = 59/140 (42%), Gaps = 19/140 (13%) Query: 560 AISQKGNEMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGAS 619 AI+ + + FSN + D+ APG DI ST Y + SGTSMATPH+AGA Sbjct: 202 AINFDRH-ASEFSNSNN------EVDLVAPGEDILSTVPGGKYATFSGTSMATPHVAGAL 254 Query: 620 LLVKQYLEALQPQLAKDKLADL-VKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAV 678 L+KQ L + L + + L+ SP+ +G GLL + Sbjct: 255 ALIKQ----LANASFERDLTEPELYAQLIKRT-------IPLGNSPKMEGNGLLYLTAVE 303 Query: 679 TSGLYLTGKDNYGSISLGNV 698 + G +S ++ Sbjct: 304 ELSRIFDTQRVAGILSTASL 323 Score = 39.8 bits (93), Expect = 6e-05 Identities = 13/29 (44%), Positives = 18/29 (62%), Gaps = 1/29 (3%) Query: 126 IKTEGAWNRGYKGQGKVIAVIDTGIDASH 154 I+ WN+ G+G +AV+DTG DA H Sbjct: 29 IQAPAVWNQTR-GRGVKVAVLDTGCDADH 56
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.1 bits (75), Expect = 8e-04 Identities = 19/130 (14%), Positives = 47/130 (36%), Gaps = 8/130 (6%) Query: 20 SEVEEELSSKKQEEPVTKSQQTSR--PNQQQQAARASQPQQPKQARPQ-MQAQQRPQSQS 76 SE +E +++ +E + ++ ++ + Q+ + + PKQ + + +Q Q P ++ Sbjct: 1090 SETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREN 1149 Query: 77 RAAYAERPYQGQSQARVSHDYNDRRATSAPSASSRREQYQHAAHQ-----EQTTIALKYP 131 + Q Q+ + + +S + + E TT A P Sbjct: 1150 DPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQP 1209 Query: 132 RKYEDAQEIV 141 ++ Sbjct: 1210 TVNSESSNKP 1219 Score = 32.3 bits (73), Expect = 0.001 Identities = 18/121 (14%), Positives = 37/121 (30%), Gaps = 6/121 (4%) Query: 25 ELSSKKQEEPVTKSQQTSRPNQQQQAARASQPQQPKQARPQMQAQQRP-QSQSRAAYAER 83 E++ E T++ +T ++ +A + Q P++ +Q P Q QS + Sbjct: 1084 EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQA 1143 Query: 84 PYQGQSQARVSHD-----YNDRRATSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQ 138 ++ V+ N T P+ + Q E+ Sbjct: 1144 EPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203 Query: 139 E 139 Sbjct: 1204 P 1204 Score = 30.0 bits (67), Expect = 0.008 Identities = 21/120 (17%), Positives = 37/120 (30%), Gaps = 2/120 (1%) Query: 21 EVEEELSSKKQEEPVTKSQQTSRPNQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAY 80 E + + K QE P SQ + P Q+Q Q + ++ P + ++ + A Sbjct: 1110 EKAKVETEKTQEVPKVTSQVS--PKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTAD 1167 Query: 81 AERPYQGQSQARVSHDYNDRRATSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEI 140 E+P + S + S E A Q K + + Sbjct: 1168 TEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSV 1227
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.048 Identities = 13/46 (28%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 125 AKRGDIDPVIGRDDEIIRVIEILNRRTKNN-PVLI-GEPGVGKTAV 168 D P++GR + + +L R + + ++I GE G GK V Sbjct: 131 DDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELV 176
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 50.8 bits (121), Expect = 3e-09 Identities = 35/84 (41%), Positives = 44/84 (52%), Gaps = 5/84 (5%) Query: 228 KGEQKPKGDQGKDTKPSAPKAPEKTPAPKAPEKSAQPKAPAPKSAPAAQKSTLPATGETN 287 K Q D KP P K AP+A K Q KAP + K LP+TGET Sbjct: 458 LRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKE-----TKRQLPSTGETA 512 Query: 288 HPFFTLAALSVITSAGVLNLKKKK 311 +PFFT AAL+V+ +AGV + K+K Sbjct: 513 NPFFTAAALTVMATAGVAAVVKRK 536
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 88.4 bits (219), Expect = 3e-25 Identities = 43/148 (29%), Positives = 82/148 (55%), Gaps = 3/148 (2%) Query: 1 MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRDMNEIGIVKIPSGTGRY 60 M K +R I++++ ++EIETQ EL+ +L G +TQAT+SRD+ E+ +VK+P+ G Y Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSY 60 Query: 61 VYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVVPGNSKLIKRYLMTDFSGQ 120 Y L D + + K+++++ K I L +PGN++ I + + Sbjct: 61 KYSLPADQRFNPLSKL---KRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE 117 Query: 121 LFSLIADDDSLLLIAKSEADADHIRQEL 148 + I DD++L+I ++ D +++++ Sbjct: 118 IMGTICGDDTILIICRTHDDTKVVQKKI 145
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 125 bits (315), Expect = 2e-41 Identities = 84/91 (92%), Positives = 89/91 (97%) Query: 1 MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQLIGFGNFEVRERAARK 60 MANKQDLIAKVAEATELTKKDSAAAVDAVFSA+ ++LA+GEKVQLIGFGNFEVRERAARK Sbjct: 1 MANKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARK 60 Query: 61 GRNPQTGEEIEIAASKVPAFKAGKALKDAVK 91 GRNPQTGEEI+I ASKVPAFKAGKALKDAVK Sbjct: 61 GRNPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 41.6 bits (97), Expect = 2e-06 Identities = 38/159 (23%), Positives = 68/159 (42%), Gaps = 16/159 (10%) Query: 111 GDTSQLDAQLQQSVALLDSATHKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTF 170 G + + +L V +++A IP N+IVYR G E L + F Sbjct: 303 GPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRS--------GPQEFGLTLTSPEYDF 354 Query: 171 DP-QILSAIK---PGTHYTKQGFMSTT--AIKNAAMPHRSVELRIQVPQGSQAAFVQPYS 224 + + + A K G T F+ST+ ++ +A R + LRI +P+ S A++ Sbjct: 355 NKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIP 414 Query: 225 FYPYEMELLFPRQCTLEI--IGANLSDDHTRLLIETRLL 261 Y E E+L +I + + T+L+++ L+ Sbjct: 415 GYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLI 453
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.1 bits (60), Expect = 0.041 Identities = 10/28 (35%), Positives = 18/28 (64%) Query: 33 MKEAEKLGGLEKLVNANGNEVKLKDMVK 60 K E+ G + VN++G+ V+LKD+ + Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVAR 267
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.0 bits (72), Expect = 0.006 Identities = 11/131 (8%), Positives = 41/131 (31%), Gaps = 3/131 (2%) Query: 113 KVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISKMEKEAKELQEKF 172 + K ++ ++ + E+ + ++ K + + + +EK + Sbjct: 182 EAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFS 241 Query: 173 DKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKKEIDKLTDKVKELEK 232 + ++K + + LE L++ ++ K ++ ++ + Sbjct: 242 TADSAKIKTLEAE---KAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKA 298 Query: 233 KATETKKSSEA 243 + A Sbjct: 299 DLEHQSQVLNA 309
>PF05272#Virulence-associated E family protein Length = 892 Score = 190 bits (484), Expect = 6e-55 Identities = 77/309 (24%), Positives = 133/309 (43%), Gaps = 19/309 (6%) Query: 42 NVLLAMKSDNKLNDFLRHNEFTGEHEIVEDVKLDAIQLRRGQLPSTFESYLSVYLENHFK 101 ++ A++S L + +E + V G L L+ Y+E + Sbjct: 454 ALIEALRSAPALAGCVAFDELREQPVAVRAFPWRK---APGPLEDADVLRLADYVETTYG 510 Query: 102 TVFKAGALRD-GIEAFFAEKTYNPVQEYMEHAYESWDHRERLAQVFQTWLGAEDSIF--- 157 T + + I +P +++++ WD RL + LG + Sbjct: 511 TGEASAQTTEQAINVAADMNRVHPFRDWVKAQ--QWDEVPRLEKWLVHVLGKTPDDYKPR 568 Query: 158 ----VQRIAVMFFVGAVSKVFNPWVKFDYTLDLVGGQGAGKTTFLQKVA-VEWYTDSAKD 212 +Q + +G V++V P KFDY++ L G G GK+T + + +++++D+ D Sbjct: 569 RLRYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFD 628 Query: 213 FMD-KDNYEIMLKSLIVNDDEMVASRKTTFDELKAFVTKTELSFRRSYGRRAEKFPKNFV 271 KD+YE + + EM A R+ + +KAF + + +R +YGR + P+ V Sbjct: 629 IGTGKDSYEQIAGIVAYELSEMTAFRRADAEAVKAFFSSRKDRYRGAYGRYVQDHPRQVV 688 Query: 272 IARTSNKVEYLGDKTGERRFLPVLVDADQQLVKPFDMTDRDVLQLWGEAVAIYKKGFTLT 331 I T+NK +YL D TG RRF PVLV L + QL+ EA+ +Y G Sbjct: 689 IWCTTNKRQYLFDITGNRRFWPVLVPGRANL----VWLQKFRGQLFAEALHLYLAGERYF 744 Query: 332 FDDDFEDEL 340 + E+ Sbjct: 745 PSPEDEEIY 753
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 34.3 bits (78), Expect = 0.004 Identities = 55/287 (19%), Positives = 112/287 (39%), Gaps = 20/287 (6%) Query: 728 RAKEERRSLTEEEKTVVTKNLNDMIQTELSLMNYSKKEKIAILKAMNGEIETLNYEQLKK 787 +AK R +LT+ K +V + L S + A AM E E L +L K Sbjct: 82 KAKANRDALTQRLKDIVNEALRHNASRTPSATELAH----ANNAAMQAEDERL---RLAK 134 Query: 788 AQEVAQKMIESENKTYKKRRSNLKEMYDNIKGDSETAVRAREEIHRQLETLEDSHTA--- 844 A+E A+K E+ K +++ KE+ + K ++E ++ E ++L L + A Sbjct: 135 AEEKARKEAEAAEKAFQEAEQRRKEI-EREKAETERQLKLAEAEEKRLAALSEEAKAVEI 193 Query: 845 KMESLGERYLKIRKKLLEDPALDPRVKQAMIDSLDKEFEKLGLSFEKLSKRSEEASSKTK 904 + L ++ K E L+ R+ ++ + D E + L KR+E A + K Sbjct: 194 AQKKLSAAQSEVVKMDGEIKTLNSRLSSSI-HARDAEMKTLA------GKRNELAQASAK 246 Query: 905 I-SMQDMTSSFRASIGEAISSLQGWDNLTPQEKQLLIDGNKAVSEILNSKTLLEQWQALT 963 + ++ + + + ++ + I K + + +T Sbjct: 247 YKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINADIT 306 Query: 964 PQQKELLAKNLTQDPTLS-AQQAIDNVKQRVPADVKASDKTAPDVAS 1009 QK + + ++ ++ +A +N+K+ + + K A D Sbjct: 307 QIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDATV 353
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 64.3 bits (156), Expect = 4e-14 Identities = 28/58 (48%), Positives = 40/58 (68%) Query: 1 MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGDGKNRYADLIYQGGP 58 M+ETI V K MT EW SD+IL + ++ +E+DTG++KFGDGKN+++ L Y P Sbjct: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKP 58
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 28.2 bits (63), Expect = 0.005 Identities = 18/73 (24%), Positives = 27/73 (36%), Gaps = 8/73 (10%) Query: 4 FVQIGTFCGAALSIFGVWGFIVNPFKKALEANELAMAQLKDSIKELAYELKNLDRDGEIT 63 Q+ C + + + F+ EL M+ KD IK E K ++ EI Sbjct: 184 LRQLMVICTVGFVVISIADYA---FEYYQYIKELKMS--KDEIKR---EYKEMEGSPEIK 235 Query: 64 KKIIDRHEERLGR 76 K H+E R Sbjct: 236 SKRRQFHQEIQSR 248
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 93.2 bits (231), Expect = 2e-23 Identities = 45/123 (36%), Positives = 63/123 (51%), Gaps = 8/123 (6%) Query: 23 SLTAAQAILESGWGKYA-------PHNALFGIKADSSWSGKSFDTKTQEEYQPGVVTDLV 75 L AQA LESGWG+ P LFG+KA +W G + T E Y+ G + Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230 Query: 76 DRFRAYDSWDESILDHGQFLVDNPRYHAVIGETDYKKACHAIKAAGYATASDYAELLIQL 135 +FR Y S+ E++ D+ L NPRY AV ++ A++ AGYAT YA L + Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290 Query: 136 IEE 138 I++ Sbjct: 291 IQQ 293
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 41.6 bits (97), Expect = 3e-06 Identities = 35/97 (36%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Query: 269 EQGPKGERGEQGPKGDRGEQGPKKEPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSA 328 E+ K + E+ K G+ + P D KP P AP+A K N K Sbjct: 446 EKLAK--QAEELAKLRAGKASDSQTP--DAKPGNKAVPGKGQAPQAGTKPNQNKAPMKET 501 Query: 329 PKASLPSTGDTSQS-FVAAALGFIASAGLL-VFKRKK 363 K LPSTG+T+ F AAAL +A+AG+ V KRK+ Sbjct: 502 -KRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKE 537
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 27.0 bits (59), Expect = 0.028 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 4/50 (8%) Query: 89 RDIDVSRAERAKLRAERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK 138 RD+D SR + +L AE E + + I E R +LRR L+ +KK Sbjct: 351 RDLDASREAKKQLEAEHQKLEEQ--NKISEASRQ--SLRRDLDASREAKK 396
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 27.6 bits (61), Expect = 0.027 Identities = 19/86 (22%), Positives = 40/86 (46%), Gaps = 13/86 (15%) Query: 24 IGQQYDIQVSNLKYMVKLMDRYGVEIVRKGKNKYYPPELKQEI---IDKVLLEGQSQLSV 80 I + Y Q S+L +V+ D G+E+ KN + +++ +K++ G ++ V Sbjct: 53 IPKDYKGQGSSLNDLVRTADELGIEVQYDEKNG---TAITKQVFGTAEKLI--GLTERGV 107 Query: 81 SLEYALPNAGMLPNWIAQYKKNGYTI 106 ++ A L + +Y+K G + Sbjct: 108 TI-----FAPQLDKLLQKYQKAGNIL 128
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 167 bits (423), Expect = 4e-49 Identities = 82/335 (24%), Positives = 124/335 (37%), Gaps = 8/335 (2%) Query: 48 DSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELEQKIPE 107 S A EA+ A A A E A+ A A + T EA A LE + E Sbjct: 205 FSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAE 264 Query: 108 LEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEALDTAKRA 167 LEK ++ A ++ + L + + L A Q + LD ++ A Sbjct: 265 LEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREA 324 Query: 168 YAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVK----AELKAAGA 223 +E Q + + + + + A A +++ + +E Sbjct: 325 KKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSL 384 Query: 224 SDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKP----EPKPE 279 ++ V+ L ++ K E E + + K E + E K Sbjct: 385 RRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKAL 444 Query: 280 PKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPKQDTNK 339 + K + K P +P K P AP+ K + KA K+ + Sbjct: 445 KEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQ 504 Query: 340 LPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN 374 LPSTGE NPFFTAAAL VMA AGVAAV R++EN Sbjct: 505 LPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN 539
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 28.3 bits (63), Expect = 0.039 Identities = 9/44 (20%), Positives = 16/44 (36%) Query: 61 QYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIPKV 104 + LK N + D +E + L N I +I ++ Sbjct: 57 VFASILKNNLVEIEYIEDLISEVLVSSVALENKFISQFILEAEI 100
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 38.3 bits (89), Expect = 2e-05 Identities = 13/95 (13%), Positives = 30/95 (31%), Gaps = 2/95 (2%) Query: 46 NVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQVSA 105 G L D+ ++ + I+K P ++ ++ + M + A Sbjct: 41 RWIAAGDGDLVVTDV--VMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGA 98 Query: 106 LDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEG 140 D++ K + I RA+ + + Sbjct: 99 YDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDS 133
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.9 bits (166), Expect = 2e-15 Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 3/123 (2%) Query: 4 AGKIYIVEDDAAILTPLKEHLSQ-NYQVLTVSNFRDIKQEVIDYKPDIILMDITLPFFNG 62 I + +DDAAI T L + LS+ Y V SN + + + D+++ D+ +P N Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 63 FYWTTEIRKT-STVPIVFISSSNDEMDTVMALNMGGDDFISKPFSL-TILDAKIAAFLRR 120 F I+K +P++ +S+ N M + A G D++ KPF L ++ A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 121 SQQ 123 ++ Sbjct: 123 KRR 125
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 53.6 bits (128), Expect = 1e-10 Identities = 44/145 (30%), Positives = 73/145 (50%), Gaps = 6/145 (4%) Query: 45 TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQA---PYYNFFGIK--GA 99 ++AF+ ++ A + +Q+ + +++AQA LES G+ + + P YN FG+K G Sbjct: 149 SKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGN 208 Query: 100 YNGSSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQ 159 + G +TT E + G + FR Y + ++L DY LL+ + A + + Q Sbjct: 209 WKGPVTEITTTEYEN-GEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQ 267 Query: 160 DATAALTGLYATDTSYNWKLNNIIE 184 A A YATD Y KL N+I+ Sbjct: 268 GAQALQDAGYATDPHYARKLTNMIQ 292
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.005 Identities = 12/48 (25%), Positives = 20/48 (41%) Query: 3 TYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVGGDKTVV 50 T + TG + ++VG + K + F V +V G T+V Sbjct: 454 TLIVEGTGDNKGSLKVGDGTVILKQQTNGSGQHAFASVGIVSGRSTLV 501
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 82.2 bits (203), Expect = 4e-19 Identities = 73/323 (22%), Positives = 124/323 (38%), Gaps = 72/323 (22%) Query: 19 VNIGTIGHVDHGKTTLTAAI---TTVLARRLPSSVNQPKDYASIDAAPEERERGITINTA 75 +NIG + HVD GKTTLT ++ + + SV+ K D ER+RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITE--LGSVD--KGTTRTDNTLLERQRGITIQTG 59 Query: 76 HVEYETATRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQV 135 ++ ID PGH D++ + + +DGAIL++++ DG QTR R++ Sbjct: 60 ITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKM 119 Query: 136 GVKHLIVFMNKVD----------------------------------------------- 148 G+ I F+NK+D Sbjct: 120 GIP-TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTV 178 Query: 149 LVDDEELLE-------LVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMEL 201 + +++LLE L +E+ S PV GSA + I L Sbjct: 179 IEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIG--------IDNL 230 Query: 202 MDTVDSYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEI 261 ++ + + L V + R +A R+ G + + D + I +++I Sbjct: 231 IEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISE-KEKI 289 Query: 262 K-KAVVTGVEMFRKQLDEGLAGD 283 K + T + ++D+ +G+ Sbjct: 290 KITEMYTSINGELCKIDKAYSGE 312
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 26.3 bits (58), Expect = 0.021 Identities = 8/35 (22%), Positives = 17/35 (48%), Gaps = 4/35 (11%) Query: 3 NLDHQKAELLEA--VHQLGYDSLRYSIFSKERPGE 35 LD +L+ +G+ SL+Y + K++ + Sbjct: 65 TLDKAVGGILQQQGWPVVGWSSLKY--YWKQKDPK 97
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 29.7 bits (66), Expect = 0.003 Identities = 14/43 (32%), Positives = 21/43 (48%) Query: 67 QAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKNVSENIRW 109 Q+G GL S++LP P E+ F ++L Y N + W Sbjct: 29 QSGPDGLASITLPLPISAERGFAPALALHYSSGGGNGPFGVGW 71
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 53.5 bits (128), Expect = 3e-09 Identities = 56/301 (18%), Positives = 114/301 (37%), Gaps = 9/301 (2%) Query: 170 YKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLE-RQAKTARQFLALDADRKQLQLD 228 K E +L+ ++ L + D + E + LE R+A + Sbjct: 83 LKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAK 142 Query: 229 ILVKDIEQDRMEQEAQ--EKALVALREDLAAYHRKRQSLEAENHRLKTKRQKLSAVAEQT 286 I + E+ + EKAL A K ++LEAE L+ ++ +L E Sbjct: 143 IKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA 202 Query: 287 QADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLAFQQEHQQKSRQL 346 + I LE + + + ++ A ++ + E + Sbjct: 203 MNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQ 262 Query: 347 DEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQEADVSNQLTAIVAQL 406 E+ +AL + S +++ ++ L + L Q ++ ++ L Sbjct: 263 AELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKAD----LEHQSQVLNANRQSLRRDL 318 Query: 407 DKESQAKASQAQEYQVLQEKVNQLSQDTQTALLA-YQASQSRLEQLLADYQELAKTVEAL 465 D +AK E+Q L+E+ N++S+ ++ +L AS+ +QL A++Q+L + + Sbjct: 319 DASREAKKQLEAEHQKLEEQ-NKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKIS 377 Query: 466 E 466 E Sbjct: 378 E 378 Score = 38.1 bits (88), Expect = 2e-04 Identities = 35/218 (16%), Positives = 81/218 (37%), Gaps = 3/218 (1%) Query: 169 KYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTA-RQFLALDADRKQLQL 227 + + + L+ LE + LE+ + A A A K L+ Sbjct: 229 DLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEA 288 Query: 228 DILVKDIEQDRMEQEAQ--EKALVALREDLAAYHRKRQSLEAENHRLKTKRQKLSAVAEQ 285 + + E+ +E ++Q +LR DL A ++ LEAE+ +L+ + + A + Sbjct: 289 EKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQS 348 Query: 286 TQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLAFQQEHQQKSRQ 345 + DL + LE + ++ + + + ++E ++ ++ + + Sbjct: 349 LRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSK 408 Query: 346 LDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALRE 383 L + + E +E + + +AL+E Sbjct: 409 LAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKE 446 Score = 36.6 bits (84), Expect = 7e-04 Identities = 49/322 (15%), Positives = 92/322 (28%), Gaps = 24/322 (7%) Query: 700 AVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKLADSKELLELLSNRQTGQSS 759 V + + A ++ T E+ + K ++ L K +D + L + + Sbjct: 34 VVNTNEVSAVATRSQTD-TLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTE 92 Query: 760 E--RLLSEKARLEEALQLLA---DEKSALTSEIEQIKENKDTIKQKKDQLSQELS----- 809 E + + +++L A E A +++E+ E + L Sbjct: 93 ELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAA 152 Query: 810 ------QARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLS-----HQVSQEA 858 +N ++A + LE A + A LE L Sbjct: 153 LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAK 212 Query: 859 IDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAFIRQQ 918 I L + L D K E + LE +A L + E + Sbjct: 213 IKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA 272 Query: 919 ARLEADLEQVIGRLRQHARSLSEELQL--SLEEAKEQASPINDTDMAAARQKLQQVQQSI 976 I L +L E + D+ A+R+ +Q++ Sbjct: 273 MNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEH 332 Query: 977 RALGPINSDAIAQFDEVSERLA 998 + L N + A + L Sbjct: 333 QKLEEQNKISEASRQSLRRDLD 354 Score = 35.0 bits (80), Expect = 0.002 Identities = 53/270 (19%), Positives = 100/270 (37%), Gaps = 14/270 (5%) Query: 676 ELEQIEKELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQ 735 LE S +IK E AA+ A + A + + Sbjct: 198 ALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAA 257 Query: 736 LAEKLADSKELLELLSNR--QTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKEN 793 L + A+ ++ LE N + L +EKA LE L + L + + ++ + Sbjct: 258 LEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRD 317 Query: 794 KDTIKQKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQ 853 D ++ K QL E + L + K A+++ L + ++ LE Sbjct: 318 LDASREAKKQLEAEHQK-------LEEQNKISEASRQSLRRDLDASREAKKQLEAEH--- 367 Query: 854 VSQEAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEA 913 Q+ +Q E +D ++E Q+ E+ +++L LE + + + Sbjct: 368 --QKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKL 425 Query: 914 FIRQQARLEADLEQVIGRLRQHARSLSEEL 943 +++A L+A LE L++ +EEL Sbjct: 426 TEKEKAELQAKLEAEAKALKEKLAKQAEEL 455
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 353 bits (907), Expect = e-118 Identities = 146/476 (30%), Positives = 259/476 (54%), Gaps = 5/476 (1%) Query: 5 SYQLKCIWSYKLIRR-EIILLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRK 63 +YQ + IW K +R + L++ YLE I + ++ + + + + +T +T + Sbjct: 16 TYQ-RLIWLSKCRKRGPLSLIEKYLESSIESKCQLVVLFFKTSSLPITEVAEKTGLTFLQ 74 Query: 64 AKEYLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYR 123 Y ++NA F LS+T+ K I+C+F +KE Y + +YASS+ L++L FL+ + Sbjct: 75 LNHYCEELNAFFPDSLSMTIQKRMISCQFTHPSKETYLYQLYASSNVLQLLAFLIKNGSH 134 Query: 124 TKCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEYG 183 ++ LT F R F+S S AY + L L++ L + +++G+EYRIRYLIA+L+ ++G Sbjct: 135 SRPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKFG 194 Query: 184 FAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQLTL 243 VY++T +D IIH+F+ + T LK + +L + F +DILL LSWKR + V++PQ + Sbjct: 195 IKVYDLTQQDKNIIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQTRI 254 Query: 244 FDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWNDKQLRL 303 F +LK+L +++ + ++ IET Q+ F++GDLDYLYL+Y+T ++SF W + +R Sbjct: 255 FQQLKKLFVYDSLKKSSRDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTPEHIRQ 314 Query: 304 VYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFF-RRCLFQLHDLISFQDYY-SK 361 + EE+ ++ L+N + L + + L FF + LF L I + + S Sbjct: 315 CCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPETNLFVSP 374 Query: 362 RYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVEVIIVENK 421 Y+G+Q L ++ +++W+ L+ H H C ++EQ+L PP+ V+ V + Sbjct: 375 YYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKHFHLFCHYVEQILRNIQPPLVVVFVASN 434 Query: 422 RALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQ-APDFVITSDNILPFLEEQ 476 +L+ ++ +L D++ PD VIT ++PF+ + Sbjct: 435 FINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITHSQLIPFVHHE 490
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 4e-05 Identities = 30/193 (15%), Positives = 69/193 (35%), Gaps = 46/193 (23%) Query: 253 DETNRMMRMISDLL--NLSRIDNHVTQLSVEMTNFTAFMTSILNRF-DLVKNQHTSTGKS 309 + M+ +S+L+ +L + L+ E+T +++ +F D ++ Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQ--------- 241 Query: 310 YEI-----VRDYPITSIWLEIDNDKMTQVIENILNNAIKYSPDGGKIIVNMKTTDTQLII 364 +E + D + + ++ ++EN + + I P GGKI++ + + + Sbjct: 242 FENQINPAIMDVQVPPMLVQT-------LVENGIKHGIAQLPQGGKILLKGTKDNGTVTL 294 Query: 365 SISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGAGLGLAIAKEIIKQRRGF---IWAKS 421 + + G K + G GL +E ++ G I Sbjct: 295 EVENTGSLALKNT------------------KESTGTGLQNVRERLQMLYGTEAQIKLSE 336 Query: 422 DYGKGSTFTIVLP 434 GK +++P Sbjct: 337 KQGKV-NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.1 bits (234), Expect = 2e-24 Identities = 29/134 (21%), Positives = 64/134 (47%), Gaps = 1/134 (0%) Query: 3 KILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEEKPDLIILDLMLPELDGLE 62 IL+ DD+ I ++ L++ GYD + DL++ D+++P+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 VAKEIRKT-SHIPIIMLSAKDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTET 121 + I+K +P++++SA+++ + E GA DY+ KPF EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 IETAVAEENASSGS 135 + + +++ Sbjct: 125 RPSKLEDDSQDGMP 138
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 29.0 bits (65), Expect = 0.034 Identities = 28/142 (19%), Positives = 52/142 (36%), Gaps = 26/142 (18%) Query: 273 ALLTGIISAIVLFNKYIDKKIATLSIGASGAVGPI-FATASAVAFGSVVTAASGFGVFSD 331 ++ GI AI + +D I ++S+G V + A AVA +V A+G D Sbjct: 128 WIIQGIYYAI---EQKVD--IISMSLGGPEDVPELHEAVKKAVASQILVMCAAGNEGDGD 182 Query: 332 IILNIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVAS 391 + G P V++ +S + ++ ++ A Sbjct: 183 DRTDELGYPGCYNEVISVGAINFDRHAS------------EFSNSNNEVDL----VAPGE 226 Query: 392 NILTIVPQSGVFLTFLSLTGLS 413 +IL+ VP + + +G S Sbjct: 227 DILSTVPGGK----YATFSGTS 244
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 118 bits (296), Expect = 3e-34 Identities = 77/259 (29%), Positives = 118/259 (45%), Gaps = 16/259 (6%) Query: 4 QVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDAVVDEYTTKGWAADSVLCDVTN 63 ++ F+TGAA GIG+ + T +G + D N EKL+ VV + A++ DV + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 64 EEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFPTAKYEFMLKVMLTAPFIAIKRAF 123 AI++ + G +DILVN AG+ +I ++E V T F A + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 124 PTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHGLIGLTKVAALEAAELGITVNAICPG 183 M + G ++ + S + AAY S+K + TK LE AE I N + PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 184 YVDTPLVRGQFEDLSKTRKIPLENVLEEVL------YPL-VPQKRLIDVQEIADYVSFLA 236 +T + + D EN E+V+ + +P K+L +IAD V FL Sbjct: 189 STETDMQWSLWAD---------ENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 237 SDKAKGITGQPVILDGGYT 255 S +A IT + +DGG T Sbjct: 240 SGQAGHITMHNLCVDGGAT 258
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 28.0 bits (62), Expect = 0.036 Identities = 11/27 (40%), Positives = 17/27 (62%), Gaps = 2/27 (7%) Query: 2 NKRISIEEAVNLVKDGDTIMVGGFMTN 28 N R ++ AV LV G+T++VGG + Sbjct: 527 NTR-TVNNAV-LVGSGETVVVGGLLDK 551
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 33.4 bits (76), Expect = 0.001 Identities = 37/174 (21%), Positives = 70/174 (40%), Gaps = 27/174 (15%) Query: 17 FNLSRTAQQLYISQPTLSIMINDFEEKQGIKLFNKKYN---KILGLTMTGKQFYEDSLE- 72 +L RTA +L I ++EK G + + + K++GLT G + L+ Sbjct: 65 NDLVRTADELGIEV--------QYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDK 116 Query: 73 VIRKYDKMHQNLFSTNQKLDGNI-----TIGIPPLILSIVFSKIMPEIILENPNIHFNIK 127 +++KY K L + + N+ + L S + + +++ N+ Sbjct: 117 LLQKYQKAGNILGGGAENIGDNLGKAGGILSTFQNFLGTALSSMKIDELIKKQKSGGNVS 176 Query: 128 EYGANRLRQELILENVDIAILLHPERIAA--NTIDSFQIQESELCAFVSKNHHL 179 + ELI + VD +A+ N ++SF Q + L + +S HL Sbjct: 177 SSELAKASIELINQLVD--------TVASLNNNVNSFSQQLNTLGSVLSNTKHL 222
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 33.7 bits (77), Expect = 0.001 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 10/82 (12%) Query: 57 IDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERLKAARIPVI 116 IDTPG H DF+ E Y +L ++ + ++ A + ++ L+ IP I Sbjct: 73 IDTPG-HM------DFLAE-VYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTI 124 Query: 117 LVINKIDK--VHPDQLLEQIDD 136 INKID+ + + + I + Sbjct: 125 FFINKIDQNGIDLSTVYQDIKE 146
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 86.3 bits (213), Expect = 2e-22 Identities = 65/252 (25%), Positives = 110/252 (43%), Gaps = 24/252 (9%) Query: 3 KRVLITGVSSGIGLAQARLFLRNGFTVYGVD----KAKKPDLSGDFQ-FLQLDITGDLAE 57 K ITG + GIG A AR G + VD K +K S + D+ + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 58 ----------LFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVRITRHY 107 + + +D+L + AGVL + + ++EA F VN +R Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 108 LAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGIQVFGIAP 167 M+ +SG I+ + S + + AAY SSK A FT+ L L+ A+ I+ ++P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 168 GAVQTAMTATDF-EPGGLAQWVADE-------TPIGRWLRAEEIAELTMFLASGKASAMQ 219 G+ +T M + + + G Q + P+ + + +IA+ +FL SG+A + Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 220 GEIVKIDGGWSL 231 + +DGG +L Sbjct: 248 MHNLCVDGGATL 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.6 bits (217), Expect = 1e-20 Identities = 31/137 (22%), Positives = 58/137 (42%), Gaps = 5/137 (3%) Query: 3 KVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYLDDCAVDVMISDVNMPGMT 62 +L+ DD+ I L + G++V +A ++ D++++DV MP Sbjct: 5 TILVADDDAAIRTVLNQAL--SRAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGYLLKPVDKKELVAKMLYFKEW 122 +L+ + P L L++S F +A E YL KP D EL+ + + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG--IIGRAL 119 Query: 123 LDEQRAASLRQAAYREG 139 + +R S + ++G Sbjct: 120 AEPKRRPSKLEDDSQDG 136
>PF06580#Sensor histidine kinase Length = 349 Score = 173 bits (441), Expect = 2e-51 Identities = 51/214 (23%), Positives = 101/214 (47%), Gaps = 17/214 (7%) Query: 359 LEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYIRMYALSCQQEELADVIYAFAALLRNN 418 ++ + + ++AQ+ AL +QINPHF++N L IR L + +++ + + L+R + Sbjct: 149 IDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILE-DPTKAREMLTSLSELMRYS 207 Query: 419 I--SQDKVTTLKEELAFCEKYIYLYQMRYPDSFAYHVKLDPVVADVEIPKFIIQPLVENY 476 + S + +L +EL + Y+ L +++ D + +++P + DV++P ++Q LVEN Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENG 267 Query: 477 FVHGIDYSRYDNALSIKALDEEDSILIQVLDNGKGISPERLVAIEKGLEEPQSTGNSSIG 536 HGI + +K + ++ ++V + G L + ++ G Sbjct: 268 IKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG-------------SLALKNTKESTGTG 314 Query: 537 LQNVYMRLFHKYRDRVTWSMSQAPTGGFRIQIRI 570 LQNV RL Y +S+ G + I Sbjct: 315 LQNVRERLQMLYGTEAQIKLSEKQ-GKVNAMVLI 347
>PF03309#Bvg accessory factor Length = 271 Score = 36.7 bits (85), Expect = 7e-05 Identities = 14/64 (21%), Positives = 25/64 (39%), Gaps = 5/64 (7%) Query: 3 LLCIDIGGTSIKFAICH----KGRLKKQSSRPT-PQSLEDFYHMLDERLAYYRTEKLSGI 57 LL ID+ T + ++ +Q T P+ D + + L E+L+G Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDGLIGDDAERLTGA 61 Query: 58 AISS 61 + S Sbjct: 62 SGLS 65
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 25.1 bits (55), Expect = 0.026 Identities = 10/64 (15%), Positives = 20/64 (31%) Query: 3 LKYIFTIVIFTFQIYFIYRSVRGLDKNNDIVDISTINSFFLLFLAHDNLMFLFILYIMIL 62 LK I +V+ + I+ I + I I L ++ ++ + Sbjct: 141 LKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVICTVGFVVISI 200 Query: 63 IDLI 66 D Sbjct: 201 ADYA 204
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 59.5 bits (144), Expect = 1e-11 Identities = 38/313 (12%), Positives = 90/313 (28%), Gaps = 44/313 (14%) Query: 27 LALLLTFLILFSCFVYKEITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDS 86 + L + S EI T+ G++T + ++ I N+ + + + +++GD Sbjct: 64 IMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDV 123 Query: 87 II-----QYAKDLEESQKQVLEKQLATYEKQKSS-------LNTLLLSLKQGQNLFQNDD 134 ++ D ++Q +L+ +L Q S L L L + ++ Sbjct: 124 LLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEE 183 Query: 135 QFGYVNTFNHFMSQAQDIDLGFSKIKAETSQQAQLIQDSIVAINQQINSLSQQISDYEEL 194 + S Q+ + + + I ++ D+ L Sbjct: 184 VLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSL 243 Query: 195 RSAIINQSDSLSSNNPHQATLDAYLSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQ 254 +++ + + + + + Q Sbjct: 244 LH-------------------KQAIAKHA----------VLEQENKYVEAVNELRVYKSQ 274 Query: 255 RANLHQSTSYDNSLNTKLEILRTQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIK 314 + S + +++ F +L +I L +L + + VI+ Sbjct: 275 LEQIESEIL---SAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIR 331 Query: 315 ASKSGIVQLNSAF 327 A S VQ Sbjct: 332 APVSVKVQQLKVH 344
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 40.6 bits (95), Expect = 3e-06 Identities = 26/133 (19%), Positives = 50/133 (37%), Gaps = 14/133 (10%) Query: 2 RVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDC--FGRPHQLLSAIKKNCGQQLFFLD 59 +++ +DD + L + L G D L I L D Sbjct: 5 TILVADDDAAIRTVLNQA---------LSRAGYDVRITSNAATLWRWIAAG-DGDLVVTD 54 Query: 60 IEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPQTEFV 119 + + +EN ++ +I++ PD ++ ++ + FM + A DY+ K TE + Sbjct: 55 VVMPDEN--AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELI 112 Query: 120 QRVETALLYAVRQ 132 + AL R+ Sbjct: 113 GIIGRALAEPKRR 125
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 26.5 bits (58), Expect = 0.012 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 5/45 (11%) Query: 33 MGGYMLIGAGSGALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMG 77 +GG L G+ +L+G AG A++ V AI GGF G Sbjct: 1030 IGGTSLNSGGNASLYGTSAG-----VDAYLNGEVEAIVGGFGSYG 1069
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 51.8 bits (124), Expect = 4e-10 Identities = 50/271 (18%), Positives = 100/271 (36%), Gaps = 40/271 (14%) Query: 14 MSTTFFIVVLSLVVFSVRMVSAEGTINIKDIYSPRWDVDKTLSPTTLREIYNRDTIKKEN 73 +S I L LV+ + +++ + D + T+ ++ +Y+ + Sbjct: 7 ISRVILIFALILVISTPNVLAESQPDPMPDDLHKSSEFTGTMG--NMKYLYDDHYVSATK 64 Query: 74 KPVTGKRGTQVIIDAQHKTKVWEFDDYNFIISSNLYPSVEGKFNVGDNVDVFGL--ALSA 131 K +I K+ +D + L + K+ + VDV+G ++ Sbjct: 65 VKSVDKFLAHDLIYNISDKKLKNYDKV---KTELLNEDLAKKYK-DEVVDVYGSNYYVNC 120 Query: 132 EVFSKDQIHSINGGLV------------KVNERKGAGKTIYMNVFIDGHKKDETSKYKIT 179 SKD + + GG + + + + V+ + K T +++ Sbjct: 121 YFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNL--QNVLVRVYEN---KRNTISFEVQ 175 Query: 180 FEKSPVTFQEVDVRLRKSFMLNDEIKLYQYG-SKVLSGNWEFHGSGENEEGADLFKYPD- 237 +K VT QE+D++ R L ++ LY++ S +G +F + N D+ P Sbjct: 176 TDKKSVTAQELDIKARN--FLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGD 233 Query: 238 ----------YRYNNLIDIDKKSHIDVYLFT 258 Y N +D K I+V+L T Sbjct: 234 KFDQSKYLMMYNDNKTVD-SKSVKIEVHLTT 263
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 46.5 bits (110), Expect = 3e-08 Identities = 43/225 (19%), Positives = 87/225 (38%), Gaps = 36/225 (16%) Query: 56 LKEIYN-KEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKKVISSNLSPSQERMFNV 114 +K +Y+ + S++ LI+N + D KV + L+ + + Sbjct: 51 MKYLYDDHYVSATKVKSVDKFLAHDLIYNISDKKLKNYD----KVKTELLNEDLAKKYK- 105 Query: 115 GDHVNIFAIVKSYHVVCKEQFNY---------IDGGIIKTSDVKPEE---KAIYINIFGE 162 + V+++ + + N + GGI K + + + + ++ Sbjct: 106 DEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYEN 165 Query: 163 KELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYD-SLYKKGFWDIHYKDG 221 K T ++ VT QE+D++ R L+ +K LYE++ S Y+ G+ +G Sbjct: 166 KRN---TISFEVQTDKKSVTAQELDIKARNFLI--NKKNLYEFNSSPYETGYIKFIENNG 220 Query: 222 GIRHTNLFTYPD-----------YTDNETIDMSKVSHFDVYLNEE 255 ++ P Y DN+T+D SK +V+L + Sbjct: 221 NTFWYDMMPAPGDKFDQSKYLMMYNDNKTVD-SKSVKIEVHLTTK 264
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 91.7 bits (227), Expect = 6e-23 Identities = 45/125 (36%), Positives = 63/125 (50%), Gaps = 8/125 (6%) Query: 23 SLTAAQAILESGWGKYA-------PHNALFGIKADSSWSGKSFDTKTQEEYQPGVVTDLV 75 L AQA LESGWG+ P LFG+KA +W G + T E Y+ G + Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230 Query: 76 DRFRAYDSWDESILDHGQFLVDNPRYKSVIGETDYKKACHAIKAAGYATASDYAELLIQL 135 +FR Y S+ E++ D+ L NPRY +V ++ A++ AGYAT YA L + Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290 Query: 136 IEQND 140 I+Q Sbjct: 291 IQQMK 295
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.0 bits (72), Expect = 0.009 Identities = 25/116 (21%), Positives = 43/116 (37%), Gaps = 11/116 (9%) Query: 143 QKLALINETIKGVKREYQDADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQK 202 + A + + + Q R L AS +A L+A+ + + + S Q L + Sbjct: 295 AEKADLEHQSQVLNANRQSLRRDLDASREA-KKQLEAEHQKLEEQNKIS-EASRQSLRRD 352 Query: 203 YDDELRKLSAKITTTSSGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQ 258 D R+ + EA KLE S Q +R +L++ K V+ Sbjct: 353 LD-ASREAKKQ--------LEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVE 399
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 65.8 bits (160), Expect = 1e-14 Identities = 28/58 (48%), Positives = 40/58 (68%) Query: 1 MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGDGKNRYADLIYQGGP 58 M+ETI V K MT EW SD+IL + ++ +E+DTG++KFGDGKN+++ L Y P Sbjct: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKP 58
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 48.1 bits (114), Expect = 6e-08 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 9/95 (9%) Query: 396 QQPKGDQGKDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSASPKAPAPQSTPSK 455 Q + + + K S + P++ P P K AP+A Q+ +P Sbjct: 451 QAEELAKLRAGKASDSQTPDAK--PGNKAVPGKGQAPQAGTKPNQNKAPMK-------ET 501 Query: 456 KAVLPATGEASHPFFSLAALSVIASAGLLTLKRKK 490 K LP+TGE ++PFF+ AAL+V+A+AG+ + ++K Sbjct: 502 KRQLPSTGETANPFFTAAALTVMATAGVAAVVKRK 536
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 35.4 bits (81), Expect = 1e-04 Identities = 18/109 (16%), Positives = 38/109 (34%), Gaps = 3/109 (2%) Query: 24 QQNQALGQNGSAQNHRKASVSEDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEF 83 + + + + +D A + + + RL + + + R+ Y++ Sbjct: 128 DKRTLKTEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTRLVIYPDEETPRLAYEVNV 187 Query: 84 DAKDQE---YSYTIDANTGEILEKSSEPITEAPASAQAAGGQADQAAGI 129 + Y IDA G++L K ++ P AQ G + G Sbjct: 188 RFLTPVPGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAGTSTVGVGR 236 Score = 31.1 bits (70), Expect = 0.002 Identities = 19/95 (20%), Positives = 37/95 (38%), Gaps = 16/95 (16%) Query: 102 LEKSSEPITEAPASAQA-AGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD 160 L+K + A + QA + D A +++++ A + + +L D+ Sbjct: 127 LDKRTLKTEAAISIQQAEMIAKQDVADRVTKERPA----------AEEGKPTRLVIYPDE 176 Query: 161 G--RVVYDIEFDAKDQE---YSYTIDANSGDILEK 190 R+ Y++ + Y IDA G +L K Sbjct: 177 ETPRLAYEVNVRFLTPVPGNWIYMIDAADGKVLNK 211
>adhesinb#Adhesin B signature. Length = 310 Score = 27.9 bits (62), Expect = 0.023 Identities = 12/59 (20%), Positives = 27/59 (45%), Gaps = 5/59 (8%) Query: 48 LADYFGVSVAYILGID-EEKYAPSNLKIVTDSFKTSEITSV----TPFKSDMEKLKKGI 101 + + V AYI I+ EE+ P +K + + + +++ S+ + M+ + K Sbjct: 212 FSKAYNVPSAYIWEINTEEEGTPDQIKTLVEKLRKTKVPSLFVESSVDDRPMKTVSKDT 270
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.017 Identities = 32/150 (21%), Positives = 50/150 (33%), Gaps = 28/150 (18%) Query: 8 RMRPRTITEVIGQQHLVGEGKIIDRMVK-----ANRLASMILYGPPGIGKTSIASAIAGT 62 R + + LVG + + + ++++ G G GK +A A+ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 63 TKYAFRTF----NATIDNKKRLQEIA----EEAKFSG-------------GLVLLLDEIH 101 K F A I + L E E+ F+G G L LDEI Sbjct: 184 GKRRNGPFVAINMAAI--PRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIG 241 Query: 102 RLDKSKQDFLLPLLEHGHIIMIGATTGNPF 131 + Q LL +L+ G +G T Sbjct: 242 DMPMDAQTRLLRVLQQGEYTTVGGRTPIRS 271
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 93.4 bits (232), Expect = 4e-25 Identities = 54/218 (24%), Positives = 95/218 (43%), Gaps = 24/218 (11%) Query: 37 TTNRHNLESLYKHDSNLIEADSIKNSPDIVTSHMLKYSVKDKNLSVF------FEKDWIS 90 T N++ LY D + + A +K S D +H L Y++ DK L + + ++ Sbjct: 45 TGTMGNMKYLY--DDHYVSATKVK-SVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLA 101 Query: 91 QEFKDKEVDIYAL---------SAQEACECPGKRYEAFGGITLTN----SEKKEIKVPIN 137 +++KD+ VD+Y S + G + +GGIT V + Sbjct: 102 KKYKDEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVR 161 Query: 138 VWDKSKQHPPMFITVNKPKVTAQEVDIKVRKLLIKKYDIYNNREQKYSKGTVTLDLNSGK 197 V++ + + +K VTAQE+DIK R LI K ++Y Y G + N+G Sbjct: 162 VYENKRNTISFEVQTDKKSVTAQELDIKARNFLINKKNLYEFNSSPYETGYIKFIENNGN 221 Query: 198 DIVFDLYYFGNGDF--NSMLKIYSNNERIDSTQFHVDV 233 +D+ F + L +Y++N+ +DS ++V Sbjct: 222 TFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEV 259
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 111 bits (280), Expect = 9e-32 Identities = 65/234 (27%), Positives = 102/234 (43%), Gaps = 35/234 (14%) Query: 42 NLRNLYSTYDPTEVKGKINEGPPFSGSLFYK--NIPYGNSSIELKVELNSVEKAKFFSGK 99 N++ LY + + K K + + L Y + N ++K EL + + AK + + Sbjct: 50 NMKYLYDDHYVSATKVK-SVDKFLAHDLIYNISDKKLKNYD-KVKTELLNEDLAKKYKDE 107 Query: 100 RVDIFTLEYSPPCNSNIKKNS----------YGGITLSDGNRID---KKNIPVNIFIDGV 146 VD++ Y C + K N YGGIT +GN D +N+ V ++ + Sbjct: 108 VVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKR 167 Query: 147 QQKYSYTDISTVSTDKKEVTIQELDVKSRYYLQKHFNIYGYGDVKDFGRSSRFQSGFEEG 206 T V TDKK VT QELD+K+R +L N+Y + S +E G Sbjct: 168 N-----TISFEVQTDKKSVTAQELDIKARNFLINKKNLYEFNS-----------SPYETG 211 Query: 207 NIIFHLNSGERISYNLFDT--GHGDRESMLKKYSDNKTAYSDQLHIDIYLVKFN 258 I F N+G Y++ D+ L Y+DNKT S + I+++L N Sbjct: 212 YIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEVHLTTKN 265
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 502 bits (1294), Expect = 0.0 Identities = 274/369 (74%), Positives = 295/369 (79%), Gaps = 37/369 (10%) Query: 4 EVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVGDGKNKFKDLKDLRGPMGPQ 63 E R+Q + MT +EW S IL+E EIG + TGY K GDGKN+F LK L Sbjct: 3 ETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYL------- 55 Query: 64 GPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFAQKKETNSKITKLESSKADKSA 123 NKP+L AFAQK+ETNSKITKLESSKADK+A Sbjct: 56 ------------------------------NKPDLGAFAQKEETNSKITKLESSKADKNA 85 Query: 124 VYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAGVVVY 183 VY KAESKIELDKKL+L GG++TGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAGVVVY Sbjct: 86 VYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAGVVVY 145 Query: 184 SNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNAVNIVMRQPTTPNFSSALNITSDNEN 243 SNNDTSDGPLMSLRTGKETFN+SALFVDY G TNAVNI MRQPTTPNFSSALNITS NEN Sbjct: 146 SNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNAVNIAMRQPTTPNFSSALNITSGNEN 205 Query: 244 GSAMQLRGSEKALGTLKITHENPNVEAKYDENATALSIDIVKKQKGGKGTAAQGIYINST 303 GSAMQ+RG EKALGTLKITHENPNVEA YDENA ALSIDIVKKQKGGKGTAAQGIYINST Sbjct: 206 GSAMQIRGVEKALGTLKITHENPNVEANYDENAAALSIDIVKKQKGGKGTAAQGIYINST 265 Query: 304 SGTTGKLLRIRNLSDDKFYVKSDGGFYAKETSQIDGNLKLKDPTANDHAATKAYVDKAIS 363 SGTTGKLLRIRNL DDKFYVK DGGFYAK+TSQIDGNLKLK+PTA+DHAATKAYVD + Sbjct: 266 SGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQIDGNLKLKNPTADDHAATKAYVDSEVK 325 Query: 364 ELKKLILKK 372 +LK L++ K Sbjct: 326 KLKALLMDK 334
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 28.9 bits (64), Expect = 0.038 Identities = 16/72 (22%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Query: 123 TSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYALGAYASYDMV--YDFDRIKMTII 180 + + ++ D +E+I+ ANQ + + G + D Y FD K + Sbjct: 850 SKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKGNV 909 Query: 181 QPRLDSVSSVDI 192 + L++++SV I Sbjct: 910 KITLNNLNSVGI 921
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 24.4 bits (53), Expect = 0.032 Identities = 9/32 (28%), Positives = 16/32 (50%) Query: 24 DLAAAYGLNRQEVTNILSGSTRGPKANQFILR 55 + A A G++ ++ +S + G N FI R Sbjct: 733 EKAQALGVSLSDINQTISTALGGTYVNDFIDR 764
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 70.9 bits (173), Expect = 3e-15 Identities = 43/90 (47%), Positives = 49/90 (54%), Gaps = 3/90 (3%) Query: 359 KPQEDAPKVPETKPETKPEAKPLSPEKADQAGKVAAPAHTASKAAAAKAEMKKTTNQLPA 418 K E+ K+ K P GK AP +K KA MK+T QLP+ Sbjct: 450 KQAEELAKLRAGKASDSQTPDA-KPGNKAVPGKGQAP-QAGTKPNQNKAPMKETKRQLPS 507 Query: 419 TGEAVNPFFTAAALAVMATAGVAAI-KRKE 447 TGE NPFFTAAAL VMATAGVAA+ KRKE Sbjct: 508 TGETANPFFTAAALTVMATAGVAAVVKRKE 537
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 48.9 bits (116), Expect = 1e-08 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 4/91 (4%) Query: 212 QKPKGDQGKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALP 271 Q + + + K S + P+ P KA Q K +K A K LP Sbjct: 451 QAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQ---APQAGTKPNQNK-APMKETKRQLP 506 Query: 272 ATGEINHPFFTLAALSVIASVGVLTLKGKKD 302 +TGE +PFFT AAL+V+A+ GV + +K+ Sbjct: 507 STGETANPFFTAAALTVMATAGVAAVVKRKE 537
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 36.1 bits (83), Expect = 8e-05 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 7/144 (4%) Query: 107 LIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMI---SMGFAIAYWSTPS 163 + W T G I VV LSL LP++ +T + S+G + + Sbjct: 118 MAWAATKAALAGAGIGVVAAALGYTQWLSL--LYALPVIALTGLAFASLGMVVTALAPSY 175 Query: 164 TMMLVTQLLLMIGLLF-SPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHSISVV 222 + Q L++ +LF S ++P +++P V FLP + DLIR + + V Sbjct: 176 DYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVC 235 Query: 223 KLV-VLLLWLVATALLSVNWLNRQ 245 + V L +++V LS L R+ Sbjct: 236 QHVGALCIYIVIPFFLSTALLRRR 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 45.2 bits (107), Expect = 1e-07 Identities = 24/127 (18%), Positives = 49/127 (38%), Gaps = 10/127 (7%) Query: 3 KIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQSLSND-YHIFLLDIEMDNM 61 I + DD+ A T + L ++ I + L + ++ + + D+ M + Sbjct: 5 TILVADDDAAIRTVLNQAL----SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 SGIALAEHIRKDNLSAIIIFLTSHKEYMENI--FHVQTFDYLIKPLNEPYFFECLNRALR 119 + L I+K ++ +++ +M I +DYL KP + E + R Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT---ELIGIIGR 117 Query: 120 VLELDKK 126 L K+ Sbjct: 118 ALAEPKR 124
>PF06580#Sensor histidine kinase Length = 349 Score = 44.1 bits (104), Expect = 6e-07 Identities = 59/353 (16%), Positives = 139/353 (39%), Gaps = 47/353 (13%) Query: 73 ISSSYRYSMKQCIFWSVTLQSIGILLEASLGIILISLKYQISSISGTFLFINLLTISSII 132 ++S++R + K +W Q IG + G SL S +F +++ ++ Sbjct: 1 MASTHRQANKY--YW--YCQGIGWGVYTLTGFGFASLYGSPKLHS--MIFNIAISLMGLV 54 Query: 133 IIFVLKQLFLKTTDNWLDEQTQTNWILKLSII----PMISLSLLLLQLLRLKEEPLFDLF 188 + + + L+ +L ++ ++ + + L + +P+ Sbjct: 55 LTHAYRSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTL 114 Query: 189 TILLTLGFIIITITSLY--LYTYISD----QHLQMQDINLDRVRFQSELKHLENVKENQL 242 + L++ F ++ +T ++ LY + ++ + + +++L L+ Q+ Sbjct: 115 PLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKA----QI 170 Query: 243 SIRALKHDLHN--QNIVLLGLLEQKQYTKAQQLLNHNLNL----LDGTDTFFTN-----D 291 + H + N NI L L + TKA+++L L L ++ + Sbjct: 171 N----PHFMFNALNNIRALIL---EDPTKAREMLTSLSELMRYSLRYSNARQVSLADELT 223 Query: 292 TILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIGNLLDNSIAATIRNQNKA 351 + +YL + L I I + +V +++ L++N I I + Sbjct: 224 VVDSYLQLASIQFEDR----LQFENQINPAI-MDVQVPPMLVQTLVENGIKHGIAQLPQ- 277 Query: 352 EKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGIKNVQKIVQQYYG 404 +I LK + +++E + LA ++ ++ G G++NV++ +Q YG Sbjct: 278 GGKILLKGTKDNGTVTLEVE---NTGSLALKNTKESTGTGLQNVRERLQMLYG 327
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 60.1 bits (145), Expect = 2e-11 Identities = 58/358 (16%), Positives = 120/358 (33%), Gaps = 17/358 (4%) Query: 150 TRNAFKVTIENLHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAETKARTAEEE 209 R+ V++ G K K R V + D E +KRN +T + Sbjct: 949 QRDHLNVSLVGNTVDLGAW---KYKLRNVN-----GRYDLYNPEVEKRN-----QTVDTT 995 Query: 210 AKQATADKEKAETEAKKAKEEAKTAKEAAHQEQEKAKQLEQANQQANQRANLAEKSKKDL 269 + + EE EA A E A ++ +K+ Sbjct: 996 NITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNE 1055 Query: 270 ETQKEKLEQEIKEATEAKNKAEQKLKDLQDSASQGSELSKQLLKEKEELTTKLQELQKQA 329 + E Q + A EAK+ + + + + S Q + KE T + +E K Sbjct: 1056 QDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVE 1115 Query: 330 EEKTTEIEKLKQELEANKQNSGQLGQQEQKLQEQLNKVQKELKQKEMELKQAQEQLKQEQ 389 EKT E+ K+ ++ ++ S + Q + +E V + Q + EQ +E Sbjct: 1116 TEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKET 1175 Query: 390 ----KPHEGGGDSDASKARITELEKQVQTLTKEKADLSSTLESTKAQLSETQARLSEAQK 445 + + + + E + T + S + K + + + + Sbjct: 1176 SSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE 1235 Query: 446 QLTAAQEKLTTLEAEKTALQHQVETISKQLSETRDLSEKEKAALQEQINKLKAEIEQK 503 T + +T+ + +S ++ + ++ A+ + I++L+ E + Sbjct: 1236 PATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293
>PF06580#Sensor histidine kinase Length = 349 Score = 32.5 bits (74), Expect = 0.005 Identities = 25/136 (18%), Positives = 54/136 (39%), Gaps = 18/136 (13%) Query: 464 QELGLKNAILDIIS-KFQKKESVIINDNIQVEQLDFGQPINNFILRSIRELINNSILHG- 521 EL + ++ L + S +F+ + N + + + ++++ L+ N I HG Sbjct: 220 DELTVVDSYLQLASIQFEDRLQFENQINPAIMDV----QVPPMLVQT---LVENGIKHGI 272 Query: 522 ----NAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEKLALLGG----- 572 +I + V +++ + G E+ GL + E+L +L G Sbjct: 273 AQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQI 332 Query: 573 QLLVDKHPTTIVMLIP 588 +L + ++LIP Sbjct: 333 KLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 51.4 bits (123), Expect = 4e-10 Identities = 24/112 (21%), Positives = 52/112 (46%), Gaps = 3/112 (2%) Query: 2 IKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLKYKSVDVLIIDLMLKDIH 61 I + DD + L L + ++V ++ L + D+++ D+++ D + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAG-YDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAFLPKECSYDELI 113 FDL+ +I++ +P ++++S + +A + G +LPK ELI Sbjct: 62 AFDLLPRIKKARPDLP-VLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELI 112
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.5 bits (76), Expect = 7e-04 Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 2/41 (4%) Query: 30 KGRFTVIL-GPSGSGKSTLLNLLGGMDRASKGTF-IFEGKD 68 K ++V+L G G GKSTL+N L G+D S F I GKD Sbjct: 594 KFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 56.6 bits (136), Expect = 3e-10 Identities = 47/309 (15%), Positives = 105/309 (33%), Gaps = 4/309 (1%) Query: 246 AEAKARTAEEEAKQATADKEKAETEAKKAKEEAKTAKEAAHQEQEKAKQLEQANQQANQR 305 E + +T + + + EE EA A E A Sbjct: 985 VEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENS 1044 Query: 306 ANLAEKSKKDLETQKEKLEQEIKEATEAKNKAEQKLKDLQDSASQGSELSKQLLKEKEEL 365 ++ +K+ + E Q + A EAK+ + + + + S Q + KE Sbjct: 1045 KQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETA 1104 Query: 366 TTKLQELQKQAEEKTTEIEKLKQELEANKQNSGQLGQQEQKLQEQLNKVQKELKQKEMEL 425 T + +E K EKT E+ K+ ++ ++ S + Q + +E V + Q + Sbjct: 1105 TVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNT 1164 Query: 426 KQAQEQLKQEQ----KPHEGGGDSDASKARITELEKQVQTLTKEKADLSSTLESTKAQLS 481 EQ +E + + + + E + T + S + K + Sbjct: 1165 TADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHR 1224 Query: 482 ETQARLSEAQKQLTAAQEKLTTLEAEKTALQHQVETISKQLSETRDLSEKEKAALQEQIN 541 + + + T + +T+ + +S ++ + ++ A+ + I+ Sbjct: 1225 RSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHIS 1284 Query: 542 KLKAEIEQK 550 +L+ E + Sbjct: 1285 QLEMNNEGQ 1293 Score = 55.1 bits (132), Expect = 9e-10 Identities = 48/317 (15%), Positives = 101/317 (31%), Gaps = 31/317 (9%) Query: 227 EEAKTAEGKVKQAETEKRNAEAKARTAE---------EEAKQATADKEKAETEAKKAKEE 277 T + N E AR E ++ E ++ E+K ++ Sbjct: 995 TNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN 1054 Query: 278 AKTAKEAAHQEQEKAKQLEQANQQANQRANLAEKSKKDLETQKEKLEQEIKEATEAKNKA 337 + A E Q +E AK+ + + Q +A+ + ETQ + ++ E K K Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 338 EQKLKDLQDSASQGSELSKQLLKEKEELTTKLQELQKQAEEKTTEIEKLKQELEANKQNS 397 E + Q+ S++S + +E+ T + + E T K Q Sbjct: 1115 E--TEKTQEVPKVTSQVSPK----QEQSETVQPQAEPARENDPTVNIKEPQSQT------ 1162 Query: 398 GQLGQQEQKLQEQLNKVQKELKQKEMELKQAQEQLKQEQKPHEGGGDSDASKARITELEK 457 EQ K ++ + + E + +E Sbjct: 1163 -----NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 458 QVQTLTKEKADLSSTLESTKAQLSETQARLSEAQKQLTAAQEKLTTLEAEKTALQHQVET 517 + + + + + S + + + + R + A LT+ +A A Q Sbjct: 1218 KPK--NRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKA---QFVA 1272 Query: 518 ISKQLSETRDLSEKEKA 534 ++ + ++ +S+ E Sbjct: 1273 LNVGKAVSQHISQLEMN 1289 Score = 53.1 bits (127), Expect = 3e-09 Identities = 37/281 (13%), Positives = 89/281 (31%), Gaps = 5/281 (1%) Query: 144 ERSKKAKEATEALNQKAQLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRT 203 ++ T N +V + NEE+ + E + E + + Sbjct: 989 NQTVDTTNIT-TPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQE 1047 Query: 204 AEETAKQAKTDKERAEAEAKKAKEEAKTAEGKVKQAETEKRNAEAK-ARTAEEEAKQATA 262 ++ K + E + AKE + + E + +E K +T E + Sbjct: 1048 SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE 1107 Query: 263 DKEKAETEAKKAKEEAKTAKEAAHQEQEKAKQLEQANQQANQRANLAEKSKKDLETQKEK 322 +EKA+ E +K +E K + + +QE+++ ++ + A + + +T Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVS-PKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTA 1166 Query: 323 LEQEIKEATEAKNKAEQKLKDLQDSASQGSELSKQLLKE--KEELTTKLQELQKQAEEKT 380 ++ + T + + ++ + E + + + ++ K ++ Sbjct: 1167 DTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRS 1226 Query: 381 TEIEKLKQELEANKQNSGQLGQQEQKLQEQLNKVQKELKQK 421 E N N V + + K Sbjct: 1227 VRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAK 1267 Score = 52.4 bits (125), Expect = 5e-09 Identities = 48/312 (15%), Positives = 99/312 (31%), Gaps = 20/312 (6%) Query: 115 ISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEA----TEALNQKAQLEATVKNIN 170 I+ + + + + + + A + T A N K + + KN Sbjct: 997 ITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 171 EELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKERAEAEAKKAKEEAK 230 + E T + +V E K + +T + A++ E E + + KE A Sbjct: 1057 DATETTAQNREVAKE-----------AKSNVKANTQTNEVAQSGSETKETQTTETKETAT 1105 Query: 231 TAEGKVKQAETEKRNAEAKARTAEEEAKQATADKEKAETEAKKAKEEAKTAKEAAHQEQE 290 + + + ETEK K T++ KQ ++ + + E + + KE Q Sbjct: 1106 VEKEEKAKVETEKTQEVPK-VTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNT 1164 Query: 291 KAKQLEQANQQANQRANLAEKSKKDLETQKEKLEQEIKEATEAKNKAEQKLKDLQDSASQ 350 A + A + ++ +S E + + + + + Sbjct: 1165 TADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHR 1224 Query: 351 GSELSKQLLKEKEELTTKLQELQKQAEEKTTEIEKLKQELEANKQ----NSGQLGQQEQK 406 S S E ++ + + +T + + A Q N G+ Q Sbjct: 1225 RSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHIS 1284 Query: 407 LQEQLNKVQKEL 418 E N+ Q + Sbjct: 1285 QLEMNNEGQYNV 1296
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 31.2 bits (70), Expect = 0.006 Identities = 16/54 (29%), Positives = 31/54 (57%), Gaps = 2/54 (3%) Query: 107 FDHVIGRYMDLIS--IEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRH 158 F + D I+ ++YS E+ +++ + + R +QL +A K+RL +I +RH Sbjct: 158 FQSKYNAFSDCIANLLKYSFEDIAFTILHYERQGDQLTKASKKRLAQIADYVRH 211
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 31.7 bits (72), Expect = 0.004 Identities = 29/188 (15%), Positives = 62/188 (32%), Gaps = 13/188 (6%) Query: 33 YVLETTNSTWYVGLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGM 92 V + Y LL + + + G D + ++ +L L+++ G + Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVL-------LVSLAGAAVDY 87 Query: 93 SLREIHASLSLTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTD 152 ++ L +++ +A + G T V A + + + A+ +MS + Sbjct: 88 AIMATAPFLW--VLYIGRIVAGITGA-TGAVAGAYIADITDGDERARHFGFMSACFGFGM 144 Query: 153 YVFTAISGFLLSVISYIPLLF---INIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLR 209 + G + + P +N + FL E E + L+ R Sbjct: 145 VAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFR 204 Query: 210 FIWHNKVV 217 + VV Sbjct: 205 WARGMTVV 212
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 42.7 bits (100), Expect = 2e-06 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 5/97 (5%) Query: 299 EKGEQSQRGEKGEQGKDTKPSAPKAPEQSPAPQVPKTSEQQSASPKVPAPKSAPSKSAAP 358 K + +++ E+ + + K S + P+ P + Q + P AP K Sbjct: 444 LKEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKE--- 500 Query: 359 AAQKGILPATGETNHPFFTLAALGVIASAGLLTLKRK 395 K LP+TGET +PFFT AAL V+A+AG+ + ++ Sbjct: 501 --TKRQLPSTGETANPFFTAAALTVMATAGVAAVVKR 535
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 27.1 bits (60), Expect = 0.037 Identities = 15/61 (24%), Positives = 24/61 (39%), Gaps = 1/61 (1%) Query: 110 DTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIP-YFKSKIDMCFELVGQY 168 D F+IL V+ L TE+ Q +R +E+ + G F K+ + Sbjct: 229 DIFMILTDVNGAALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWG 288 Query: 169 G 169 G Sbjct: 289 G 289
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 28.8 bits (64), Expect = 0.019 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 4/63 (6%) Query: 174 MSVLFNIVTGVAIALTIPAAGALLVSTIM-VLPASIAMRLGKNFKSVIFLGIMIGFTGML 232 M ++ + G+A++ + A A ++T L SI LGKNFK+ GI I + Sbjct: 3 MKLVTAAIMGLAMSTAMAATDATSLTTDKDKLSYSIGADLGKNFKN---QGIDINPDVLA 59 Query: 233 SGI 235 G+ Sbjct: 60 KGM 62
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.9 bits (64), Expect = 0.032 Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 7 IIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAGTGGGRCNVTNSGSHD 59 + +G PAG+ ++Y K + K LG +LA RCN+ + GS + Sbjct: 140 VTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY-NIRCNIVSPGSTE 191
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.3 bits (73), Expect = 0.001 Identities = 23/107 (21%), Positives = 45/107 (42%), Gaps = 13/107 (12%) Query: 80 EPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAAKDEQMRIK-DVQIAEKDKQL 138 E ++E +KQ K E ++ AK+ + +K + Q E + Sbjct: 1038 ETVAENSKQES--------KTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQS- 1088 Query: 139 DQQQQLTAKAMADKETLKLELEE-AKAEADQVRLQAEEIQSEMGPKK 184 + + KET +E EE AK E ++ + + ++ S++ PK+ Sbjct: 1089 -GSETKETQTTETKETATVEKEEKAKVETEKTQ-EVPKVTSQVSPKQ 1133
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 25.9 bits (56), Expect = 0.034 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 7/85 (8%) Query: 9 KQAQKLQKQMEQKQADLAAMQFTGKSAQELVTA-----TFTGDKQLVSIDFKEAVVDPED 63 +QAQK QK +K+ + A + + L A + +K L + ++ + + Sbjct: 156 EQAQKAQKDKREKRKEERAKNRA--NLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQ 213 Query: 64 IETLQDMTAQAINAALAQIDEATKK 88 +E L+DM QA AL QI+E KK Sbjct: 214 MERLEDMQEQAQANALKQIEELNKK 238
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 33.8 bits (77), Expect = 3e-04 Identities = 16/97 (16%), Positives = 36/97 (37%), Gaps = 13/97 (13%) Query: 99 SEAPQPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAA 158 +E P+P ++ T++ QK+D +LN N + LE +E + + Sbjct: 50 NEQPKPESSELTTEKAGQKMD----------DMLNSNDMIKLAPKEMPLESAEKEEKKSE 99 Query: 159 PQLTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY 195 ++ ++ D + Y N+ + + Sbjct: 100 DNKKSEEDHTEEINDKIYSLNY---NELEVLAKNGET 133 Score = 28.4 bits (63), Expect = 0.022 Identities = 22/115 (19%), Positives = 42/115 (36%), Gaps = 16/115 (13%) Query: 20 LTSAMFAGGAFLALGSAP---AVSASTHAGNDQPATQRLTDQEIYERA-QKLDLPDYVRG 75 LT+A+ G A + + T N+QP + + + E+A QK+D Sbjct: 20 LTAALIVGNLVTANADSNKQNTANTETTTTNEQPKPE--SSELTTEKAGQKMD------- 70 Query: 76 SIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQLTDQDAQKLDLPDYVRGSIYG 130 +LN N + LE +E + + ++ ++ D + Y Sbjct: 71 ---DMLNSNDMIKLAPKEMPLESAEKEEKKSEDNKKSEEDHTEEINDKIYSLNYN 122
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 7e-04 Identities = 18/106 (16%), Positives = 35/106 (33%), Gaps = 26/106 (24%) Query: 244 LVSNALKY----SKANTALTIHAYQQEQSIRIDVIDQGQGIKKEDLPLIFKRLYRVEASR 299 LV N +K+ + + + ++ ++V + G K Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT--------------- 307 Query: 300 NMKTGGHGLGLSIARQLARQLGGD---IAVESQLGKGSCFSLLLPA 342 G GL R+ + L G I + + GK + +L+P Sbjct: 308 ---KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIPG 349
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 306 bits (785), Expect = e-100 Identities = 137/503 (27%), Positives = 254/503 (50%), Gaps = 10/503 (1%) Query: 1 MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKRYIHQLEELFQGDIAFE 60 ++E+YLE I + L+ + + + +KTG + + Y +L F ++ Sbjct: 34 LIEKYLESSIESKCQLVVLFFKTSSLPITEVAEKTGLTFLQLNHYCEELNAFFPDSLSMT 93 Query: 61 WDSTIVRCTVLKRGK-PFLKTIYRQSVRLHILKFLLIKAPCYKVKSVSGFAREHFISTPS 119 ++ C K +L +Y S L +L FL+ + ++ FAR HF+S S Sbjct: 94 IQKRMISCQFTHPSKETYLYQLYASSNVLQLLAFLIKNGS--HSRPLTDFARSHFLSNSS 151 Query: 120 AYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDKYGIVIYELTDHDLDIVHDF 179 AYR+ + + P + L L N +VGEE+RIRYLIALL+ K+GI +Y+LT D +I+H F Sbjct: 152 AYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKFGIKVYDLTQQDKNIIHSF 211 Query: 180 IFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIPQEGIFKRLKSLALYGYLEDFF 239 + P L + F F+D+LL+LSWKR +F V IPQ IF++LK L +Y L+ Sbjct: 212 LSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQTRIFQQLKKLFVYDSLKKSS 271 Query: 240 KREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWSEEDSSALLTIIQEDPAYQELLGE 299 + + ++F + ++DY++L+Y+T NNSF+ QW+ E + +E+ ++ LL Sbjct: 272 RDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTPEHIRQCCQLFEENDTFRLLLNP 331 Query: 300 LRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIPQ-KYYYAEEYQGSKLLANRIELMIN 358 + L + + ++ L+ + + LF+L FIP+ + + Y+G++ L ++L++ Sbjct: 332 IITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPETNLFVSPYYKGNQKLYTSLKLIVE 391 Query: 359 SWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPPLAIAVIEINKKNIDILYSLVMQQVSP 418 W ++ G L + HL C +EQ++R PPL + + N N +L + S Sbjct: 392 EWMAKLPGKRYLNHKHFHLFCHYVEQILRNIQPPLVVVFVASNFINAHLLTDSFPRYFSD 451 Query: 419 CVAKVYRFNILSEAELPWRTDF-DLIVTTAEMTAFIEERLSLNENTKILDFNFDFVMYQA 477 + + +L + DL++T +++ F+ L+ + F+ + Q Sbjct: 452 KSIDFHSYYLLQDNVYQIPDLKPDLVITHSQLIPFVHHELTKGIAVAEISFDESILSIQ- 510 Query: 478 EYLSQVIRELRDKQYQEALDTIL 500 +++ +++++++Q L L Sbjct: 511 ----ELMYQVKEEKFQADLTKQL 529
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 9e-22 Identities = 31/129 (24%), Positives = 59/129 (45%), Gaps = 6/129 (4%) Query: 3 SLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELFQENPYDIVLTDINMPKLN 62 ++L+ +D+ +R + + + + N W D+V+TD+ MP N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY---DVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKSDVEEMLKKLKQK 122 L IK P ++ ++ + F A+ A + GA DYL KPF D+ E++ + + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF---DLTELIGIIGRA 118 Query: 123 LEKLKKTEA 131 L + K+ + Sbjct: 119 LAEPKRRPS 127
>PF06580#Sensor histidine kinase Length = 349 Score = 187 bits (477), Expect = 1e-56 Identities = 58/202 (28%), Positives = 101/202 (50%), Gaps = 9/202 (4%) Query: 362 EKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSQRVVDVTKSLAKYFRLALNQGN- 420 + +L AL +QINPHF++N L+ I + D + ++ SL++ R +L N Sbjct: 155 ASMAQEAQLMALKAQINPHFMFNALNNIRALIL-EDPTKAREMLTSLSELMRYSLRYSNA 213 Query: 421 ELISLADELDHARQYLFIQKQRYGDKLHYEIKGLEKYQDFMIPKLILQPLVENAIYHGIK 480 +SLADEL YL + ++ D+L +E + D +P +++Q LVEN I HGI Sbjct: 214 RQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA 273 Query: 481 EVDRPGMIRVTVLEADRHVILSVWDNGKGISLADDSSQALLECGGVGLKNVDQRLKLQYG 540 ++ + G I + + + V L V + G S G GL+NV +RL++ YG Sbjct: 274 QLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES------TGTGLQNVRERLQMLYG 327 Query: 541 HLYRMAITSEQAVFTEIKLYLP 562 ++ ++ +Q + + +P Sbjct: 328 TEAQIKLSEKQGKVNAM-VLIP 348
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 123 bits (311), Expect = 4e-39 Identities = 63/146 (43%), Positives = 93/146 (63%), Gaps = 2/146 (1%) Query: 1 MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSRDMKELNLVKVTTGNDT 60 MNK + RH IR +I+ I TQ EL + L+K+G ++TQAT+SRD+KEL+LVKV T N + Sbjct: 1 MNKGQ-RHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGS 59 Query: 61 HYEALAISQTRWEH-RLRFYMEDALVMLRVVQHQIILKTLPGLAQSFGSILDAMQISEIV 119 + +L Q +L+ + DA V + H I+LKT+PG AQ+ G+++D + EI+ Sbjct: 60 YKYSLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEEIM 119 Query: 120 ATICGDDTCLIICEDNEQAKACFEIL 145 TICGDDT LIIC ++ K + + Sbjct: 120 GTICGDDTILIICRTHDDTKVVQKKI 145
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 568 bits (1466), Expect = 0.0 Identities = 189/410 (46%), Positives = 274/410 (66%), Gaps = 9/410 (2%) Query: 5 TPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDE 64 PI+++SEIG+LKKVLLHRPG+E+ENL P ++ LFDDIP+LE A++EH+ FA L++ Sbjct: 6 NPINIFSEIGRLKKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQEHEVFASILKNN 65 Query: 65 GVEVLYLETLAAESLVTP-EIREAFIDEYLSEANIRGRATKKAIRELLMSIEDNQELIEK 123 VE+ Y+E L +E LV+ + FI +++ EA I+ T +++ S+ +I K Sbjct: 66 LVEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINLLKDYFSSL-TIDNMISK 124 Query: 124 TMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSE 183 ++GV EL ++ L DLV + F IDPMPN+ FTRDPFA+IG GV++N MF++ Sbjct: 125 MISGVVTEELKNYTSS---LDDLVNGANLFIIDPMPNVLFTRDPFASIGNGVTINKMFTK 181 Query: 184 TRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAA 243 R RETI+ +YIF +HP+Y VP+ +R E +EGGDELVL+K +L +GIS+RT+A Sbjct: 182 VRQRETIFAEYIFKYHPVYKE-NVPIWLNRWEEASLEGGDELVLNKGLLVIGISERTEAK 240 Query: 244 SIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSV 303 S+EKL +++FK F +LAF+ NR +MHLDTVFT +DY FT + +Y + Sbjct: 241 SVEKLAISLFKNKTSFDTILAFQIPKNRSYMHLDTVFTQIDYSVFTSFTSDDMYFSIYVL 300 Query: 304 TYENE--ELRIVEETGDLAELLAANLGVERVELIRCGGDNLVAAGREQWNDGSNTLTIAP 361 TY ++ I +E + ++L+ LG ++++I+C G +L+ REQWNDG+N L IAP Sbjct: 301 TYNPSSSKIHIKKEKARIKDVLSFYLG-RKIDIIKCAGGDLIHGAREQWNDGANVLAIAP 359 Query: 362 GVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI 411 G ++ Y+RN +TN + E G+K+ +I SEL RGRGGPRCMSMP REDI Sbjct: 360 GEIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGPRCMSMPLIREDI 409
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 37.9 bits (88), Expect = 4e-06 Identities = 14/65 (21%), Positives = 27/65 (41%), Gaps = 5/65 (7%) Query: 8 NQPFQRAASLY-IRYQVFV--LERQIDRQD--EFDCFDDNDRVYAVLYDGDQPVSTARFL 62 ++ L+ +R + F L + D EFD +D+N+ Y + + + RF+ Sbjct: 11 LLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNNNTTYLFGIKDNTVICSLRFI 70 Query: 63 PTAKD 67 T Sbjct: 71 ETKYP 75
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 409 bits (1054), Expect = e-147 Identities = 143/315 (45%), Positives = 206/315 (65%), Gaps = 6/315 (1%) Query: 3 KQKIVVALGGNAIL--STDASAKAQQEALVSTSKSLVKLIKEGHEVIITHGNGPQVGNLL 60 +++V+ALGGNA+ S + + + T++ + ++I G+EV+ITHGNGPQVG+LL Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61 Query: 61 LQQAAADSEKN-PAMPLDTCVAMTEGSIGFWLVNALDNELQAQGITKEVAAVVTQVIVDE 119 L A + PA P+D AM++G IG+ + AL NEL+ +G+ K+V ++TQ IVD+ Sbjct: 62 LHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDK 121 Query: 120 NDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWRKVVPSPKPIGIKEANVIRS 179 NDPAF+NPTKP+GPF EE AK+ E G KED+GRGWR+VVPSP P G EA I+ Sbjct: 122 NDPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKK 181 Query: 180 LVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFASQTLSELVDADLFIVLTGVDN 239 LV+ GV+V+++GGGGVPV+ + + GVEAVIDKD A + L+E V+AD+F++LT V+ Sbjct: 182 LVERGVIVIASGGGGVPVILE--DGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNG 239 Query: 240 VYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLPKVEAAIAFVENKSNAKAIITSLE 299 + + ++ L EV V ++++Y + F GSM PKV AAI F+E +AII LE Sbjct: 240 AALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGE-RAIIAHLE 298 Query: 300 NIDNVLSANAGTQII 314 L GTQ++ Sbjct: 299 KAVEALEGKTGTQVL 313
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 153 bits (389), Expect = 2e-50 Identities = 58/157 (36%), Positives = 94/157 (59%), Gaps = 2/157 (1%) Query: 5 IGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQSFFTFELRAQMLSEAVCALP 64 +Y GSFDP+T GH+D+I+R LF+ VYV + NPNKQ F+ + R + +++A+ LP Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 65 NVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEIGLEYFNHRLAPDIETIYLMATH 124 N V S E GL V+ AR+ ++RGLR +DF+ E+ + N LA D+ET++L + Sbjct: 62 NAQVDSFE-GLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTST 120 Query: 125 DLQPVSSSRIRELIAFRAPITGLVPQAVINQV-EKMN 160 + +SSS ++E+ F + VP V + ++ + Sbjct: 121 EYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFH 157
>BACSURFANTGN#Yersinia/Haemophilus virulence surface antigen signature. Length = 322 Score = 29.3 bits (65), Expect = 0.021 Identities = 25/98 (25%), Positives = 36/98 (36%), Gaps = 11/98 (11%) Query: 123 IKKQRDLNSGEITAQIMMVQNYFDKRAQDER-------VSHVVVMGIGEPFDNYQNVMTF 175 IK+ + Q + ++F K ER + V V G E + Sbjct: 177 IKQLQIDGCKADVDQDEVTLDWFKKNGISERMIERHCLLRPVDVTGTTESEG----LDQL 232 Query: 176 LRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQV 213 L I D HG+ G + I +S AH I + NE V Sbjct: 233 LNAILDTHGIGYGYKKIHLSGQMSAHAIAAYVNEKSGV 270
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 35.2 bits (81), Expect = 1e-04 Identities = 42/170 (24%), Positives = 65/170 (38%), Gaps = 26/170 (15%) Query: 64 VMLPYLEIITSLIFGLAALCGLTWTQLY----LLCFSLLLCFFDLDSQEYPLLIWLMSFL 119 P +E++T+L+ A+ L + L F DLD P + L Sbjct: 108 ARYPLVELLTALLSVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLW 167 Query: 120 FLLPFYSINLLTVL----------LLLLALLSVAFPI-----NIGAGDFLYLANLALVVK 164 L F + L L+L L AF + +G GDF LA L + Sbjct: 168 GGLLFNLLGGFVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLG 227 Query: 165 LSSLLWIVQIASLIGILACLLLQ-------TKKIPFIPYLTLGLIAILLF 207 +L ++ ++SL+G + L +K IPF PYL + LL+ Sbjct: 228 WQALPIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLW 277
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 146 bits (370), Expect = 1e-47 Identities = 48/154 (31%), Positives = 87/154 (56%), Gaps = 4/154 (2%) Query: 19 KKEASKNEKT--KAVLNQAVADLSVAASIVHQVHWYMRGPGFLYLHPKMDELLDRLNANL 76 K E +K +T + LN +++ + S +H+ HWY++GP F LH K +EL D + Sbjct: 2 KTENAKTNQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETV 61 Query: 77 DEMSERLITIGGAPYSTLEEFSQHSKLDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGL 136 D ++ERL+ IGG P +T++E+++H+ + + + S ++ + LV Y ++S + + Sbjct: 62 DTIAERLLAIGGQPVATVKEYTEHASITDGGN--ETSASEMVQALVNDYKQISSESKFVI 119 Query: 137 DITDEEGDAASNDLFTAAKADAEKTIWMLQAERG 170 + +E D A+ DLF + EK +WML + G Sbjct: 120 GLAEENQDNATADLFVGLIEEVEKQVWMLSSYLG 153
>PF03309#Bvg accessory factor Length = 271 Score = 29.0 bits (65), Expect = 0.024 Identities = 30/126 (23%), Positives = 42/126 (33%), Gaps = 14/126 (11%) Query: 5 LIGIDLGGTTIKFGILTSEGDVQE---KWAIETNVLEDGKHIVPDIVASLKHRLDLYGLT 61 L+ ID+ T G+++ GD + +W I T + D +A L G Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTE-----PEVTADELALTIDG--LIGDD 54 Query: 62 KDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIERELGIPFAIDNDANVAALG 121 + G S V H V W V GIP +DN V A Sbjct: 55 AERLTGASGLS--TVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVGA-- 110 Query: 122 ERWVGA 127 +R V Sbjct: 111 DRIVNC 116
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 187 bits (477), Expect = 9e-54 Identities = 107/477 (22%), Positives = 192/477 (40%), Gaps = 97/477 (20%) Query: 8 IRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQE--RAMDSNDLEKERGITILAKNTA 65 I N+ ++AHVD GKTTL + LL S + E + + D+ LE++RGITI T+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 66 VAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQNLT 125 + + ++NI+DTPGH DF EV R + ++DG +L++ A +G QTR + + + Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 126 PIVVVNKIDKPSARPAEVVDEVLELF---------IELG-------------------AD 157 I +NKID+ + V ++ E +EL + Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182 Query: 158 DDQLE--------------------------FPVVYASAINGTSSLSDDPADQEKTMAPI 191 DD LE FPV + SA N + + Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNN------------IGIDNL 230 Query: 192 FDTIIDHIPAPVDNSAEPLQFQVSLLDYNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTT 251 + I + + L +V ++Y++ R+ R++ G + + D V +S Sbjct: 231 IEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRIS----EK 286 Query: 252 KNFRVTKLFGFFGLERKEIQEAKAGDLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPT 311 + ++T+++ E +I +A +G+++ + E + + + T + + P Sbjct: 287 EKIKITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPL 345 Query: 312 LQMTFLVNNSPFAGREGKWVTSRKVEER--LLVELQT----DVSLRVEPTESPDKWIVSG 365 LQ T V K ++R LL L D LR + + I+S Sbjct: 346 LQTT---------------VEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSF 390 Query: 366 RGELHLSILIETMRRE-GYELQVSRPEVIIKEIDGVKCEPFERVQIDTPEEYQGAII 421 G++ + + ++ + E+++ P VI E K E + I+ P A I Sbjct: 391 LGKVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAE--YTIHIEVPPNPFWASI 445 Score = 42.9 bits (101), Expect = 3e-06 Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 1/80 (1%) Query: 403 EPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPARGLIGYSTEFLS 462 EP+ +I P+EY + +++D Q + N + L IPAR + Y ++ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRSDLTF 595 Query: 463 MTRGYGIMNHTFDQYLPVVA 482 T G + Y Sbjct: 596 FTNGRSVCLTELKGYHVTTG 615
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.9 bits (69), Expect = 0.008 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 11/69 (15%) Query: 332 TTAEIENMPE---VPASAQASQADKPAEASPEQG--------EEQATQEQPSPETPANPE 380 TT +++ +P P SA+A A E SP + E T+ P P+ NP+ Sbjct: 303 TTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPD 362 Query: 381 ATNPSVAQP 389 A + QP Sbjct: 363 ANPDTDGQP 371
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 49.4 bits (118), Expect = 1e-08 Identities = 42/191 (21%), Positives = 78/191 (40%), Gaps = 16/191 (8%) Query: 170 RKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVASMRAQELQYTNI 229 R++ + AG + +I P+A A G+ V+D+GGG T VA + + Y++ Sbjct: 127 RESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSS 186 Query: 230 YAEGGEYITKDISKVLKTSMSI------AEALKYNFGQADMAEASLTDTVKVDVVGSDEP 283 GG+ + I ++ + AE +K+ G A + V+ + P Sbjct: 187 VRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVP 246 Query: 284 --VEVTERYLSEIISARVRHILDRVKQDLER------GRLLDLPGGIVLIGGGAIMPGVV 335 + + E + + I+ V LE+ + + G+VL GGGA++ + Sbjct: 247 RGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISE--RGMVLTGGGALLRNLD 304 Query: 336 EVAQEIFGTNV 346 + E G V Sbjct: 305 RLLMEETGIPV 315 Score = 29.3 bits (66), Expect = 0.030 Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 42 VKDGIIIDIEAAAAAIKTAVEQAEEKAGMT-IERVNVGLPANLLQIE 87 +KDG+I D ++ ++Q + M RV V +P Q+E Sbjct: 76 MKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVE 122
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 82.0 bits (202), Expect = 6e-19 Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 8/142 (5%) Query: 274 EPEAKPKPMPKPETKPEVKPEAKPMPKPEPKPEPEAKPKPMPKPETKPEVKPEAKPMPKP 333 E +K + K + E + K E + + EA+ K + + K + K Sbjct: 404 EANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKA 463 Query: 334 EPKPEPEAKPKPMPKPETKPEVKPEAKPMPKPEAQKGDKPAVPKAMEHKLPSTGEATAPF 393 P+AKP P + KP K + +LPSTGE PF Sbjct: 464 SDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAP--------MKETKRQLPSTGETANPF 515 Query: 394 FTAAALAVLASLGVAVVSRKRK 415 FTAAAL V+A+ GVA V ++++ Sbjct: 516 FTAAALTVMATAGVAAVVKRKE 537 Score = 44.3 bits (104), Expect = 6e-07 Identities = 18/95 (18%), Positives = 33/95 (34%), Gaps = 2/95 (2%) Query: 230 LEEPMPKPEPKPEPEAKPKPMPKPETKPEVKPEAKPMPKPEPKPEPEAKPKPMPKPETKP 289 LE+ + E + K K + + + E K + + K + K P Sbjct: 412 LEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQ--TP 469 Query: 290 EVKPEAKPMPKPEPKPEPEAKPKPMPKPETKPEVK 324 + KP K +P P+ KP P + + + Sbjct: 470 DAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQ 504
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.8 bits (82), Expect = 0.001 Identities = 11/48 (22%), Positives = 17/48 (35%) Query: 13 EERQLFGIRKLKLGVASVAIATAFSLGTASGQITAAAESLTSVEPADG 60 + + +RKLK G ASVA+A + T + Sbjct: 5 NTNRHYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTL 52
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.4 bits (66), Expect = 0.009 Identities = 15/67 (22%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Query: 90 MESLEIVDAKGHDEPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDI 149 +E++E V + P + + + +I ++ + AVF+ + G S I + Sbjct: 413 VENVERVMMEDKLPPKE-ATEKSMSQIQGALVGIAM-VLSAVFIPMAFFGGSTGAIYRQF 470 Query: 150 GITVSSA 156 IT+ SA Sbjct: 471 SITIVSA 477
>FLAGELLIN#Flagellin signature. Length = 507 Score = 28.5 bits (63), Expect = 0.025 Identities = 8/25 (32%), Positives = 14/25 (56%) Query: 150 EISELQARKIQQQLKQAMLKEANAT 174 E+S + +I QQ ++L +AN Sbjct: 474 EVSNMSKAQILQQAGTSVLAQANQV 498
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 51.9 bits (124), Expect = 1e-10 Identities = 19/94 (20%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Query: 1 MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTFYLHYRDKHDMMTHLIN 60 T+ ++ + L +++ + ++ ++ K AGV RG Y H++DK D+ + + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 DTLDDLYQLLNDP--HIFTDTRLVLKEALAYIID 92 + ++ +L + D VL+E L ++++ Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLE 98
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.010 Identities = 11/25 (44%), Positives = 17/25 (68%), Gaps = 1/25 (4%) Query: 34 ELVIIL-GASGAGKSTVLNILGGMD 57 + ++L G G GKST++N L G+D Sbjct: 596 DYSVVLEGTGGIGKSTLINTLVGLD 620
>CHLAMIDIAOM6#Chlamydia cysteine-rich outer membrane protein 6 signature. Length = 547 Score = 33.5 bits (76), Expect = 0.004 Identities = 36/160 (22%), Positives = 68/160 (42%), Gaps = 16/160 (10%) Query: 516 RMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLT---AYDMLVVEAPTA------- 565 R +T+ V SVA LF+ +++S+A SLS L A D ++ A Sbjct: 6 RRAVTIFAVT-SVASLFASGVLETSMAESLSTNVISLADTKAKDNTSHKSKKARKNHSKE 64 Query: 566 EAHDRQELAQYLKADQIASKKEIYYANL-SLKIKDLDNKQTVSLISSDQSTLSPYFSLIG 624 DR+E+A ++ K++ + + ++K+ D N + + + SPY I Sbjct: 65 TPVDRKEVAPVHESKATGPKQDSCFGRMYTVKVNDDRNVEITQAVPEYATVGSPYPIEIT 124 Query: 625 AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGK 664 A ++ V+I+++L + D ++GK Sbjct: 125 ATGKRD----CVDVIITQQLPCEAEFVRSDPATTPTADGK 160
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 28.3 bits (63), Expect = 0.021 Identities = 6/21 (28%), Positives = 11/21 (52%) Query: 124 SAIGQALLKAADHGKDVINLS 144 I Q + A + D+I++S Sbjct: 127 DWIIQGIYYAIEQKVDIISMS 147
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 27.1 bits (60), Expect = 0.024 Identities = 12/21 (57%), Positives = 15/21 (71%), Gaps = 1/21 (4%) Query: 61 KTDPAYQAPPKRIGRPEYDKE 81 K DPA+Q P K +G P YD+E Sbjct: 121 KNDPAFQNPTKPVG-PFYDEE 140
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 197 bits (502), Expect = 2e-63 Identities = 74/305 (24%), Positives = 127/305 (41%), Gaps = 11/305 (3%) Query: 10 VAVGLLAVLLGLSACHQSS-SSRKAGLVIKTSFYPIYAMTKEICGDLNDVQVIAQ-NTSI 67 + V L+ ++ ++ ++ L + + I +TK I GD D+ I Sbjct: 7 LLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDP 66 Query: 68 HSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAPQLEKKGLAVMEGTSHLTLDKVQGLE 127 H YEP P V K + D+ Y+ LE K + + G++ Sbjct: 67 HEYEPLPEDVKKTSEADLIFYNGINLET---GGNAWFTKLVENAKKTENKDYFAVSDGVD 123 Query: 128 HFTIKKGMNTDALYDPHTWTDPILASQEAEQIAALLSQKDPAHKAVYLQNAKRFKAKAQK 187 ++ DPH W + A+ IA LS KDP +K Y +N K + K K Sbjct: 124 VIYLEGQNEKG-KEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDK 182 Query: 188 LVKTYKEKFESLG--RKTFVTQHTAFSYLAKRFDLKQLGIAGISPEQEPSPRQLAQIDRF 245 L K K+KF + +K VT AF Y +K + + I I+ E+E +P Q+ + Sbjct: 183 LDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGTPEQIKTLVEK 242 Query: 246 IKKYDVKTIFVEENASDKLAKTLAQSNGVAID---ILSPLEVVPADQKTYLEHLKMNLET 302 +++ V ++FVE + D+ KT++Q + I + + +Y +K NL+ Sbjct: 243 LRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGDSYYSMMKYNLDK 302 Query: 303 LYRVL 307 + L Sbjct: 303 IAEGL 307
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 28.7 bits (64), Expect = 0.027 Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 5/59 (8%) Query: 235 YGLTKA---VTPDQINLIINFALNLSNSGVISNENFTKTLNALKDSIVEKAGSTFKNIN 290 YG+ K + DQ N I + A L+N + N + ALK +EK F+N+ Sbjct: 2 YGVIKMEAFIRSDQYNFIKSQAYILAN--GHATANDRGVIQALKSLAIEKIIHVFENLT 58
>adhesinb#Adhesin B signature. Length = 310 Score = 28.7 bits (64), Expect = 0.043 Identities = 18/81 (22%), Positives = 31/81 (38%), Gaps = 2/81 (2%) Query: 227 LMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARLTDQKQSLQRY 286 Y N L++ + P + YE LKA ++L+ K++ + +K+ + Sbjct: 147 NGIIYAQNIAKRLSEKD-PANKETYEKNLKAYVEKLSALDKEAKEKFNNIPGEKKMIVTS 205 Query: 287 LSEFKDFLDKYPDEVV-IAGI 306 FK F Y I I Sbjct: 206 EGCFKYFSKAYNVPSAYIWEI 226
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 42.8 bits (101), Expect = 2e-06 Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 20/81 (24%) Query: 20 ADVLIDNGRILRIA----PDIEHD-------EVEQIDASGLVVAPGLVDIHVHFREPGQT 68 AD+ + +GRI I PD++ E I G +V G +D H+HF P Q Sbjct: 86 ADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFICPQQ- 144 Query: 69 HKEDIHTGALAAAAGGVTTVV 89 A G+T ++ Sbjct: 145 --------IEEALMSGLTCML 157
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.5 bits (79), Expect = 5e-05 Identities = 14/74 (18%), Positives = 32/74 (43%) Query: 23 EASGIKRPTKDEARLSQMLKHSNYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQ 82 K+ D+ +S + + + + + +G + +++ I D+AV + Y+ Sbjct: 43 SKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYR 102 Query: 83 GQGIGKQLLSFISE 96 +G+G LL E Sbjct: 103 KKGVGTALLHKAIE 116
>adhesinb#Adhesin B signature. Length = 310 Score = 28.3 bits (63), Expect = 0.038 Identities = 15/35 (42%), Positives = 21/35 (60%) Query: 1 MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIK 35 MKK L+ + LA + LAAC SQ S+ +T K+ Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLN 35
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.4 bits (76), Expect = 4e-04 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 6/64 (9%) Query: 149 ADNEANLLTN-GSTIYLAIKEGKIIGDI---TAWECGDYIEMDDFSVDEAYRGRGIGTAL 204 D + + + G +L E IG I + W Y ++D +V + YR +G+GTAL Sbjct: 53 DDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWN--GYALIEDIAVAKDYRKKGVGTAL 110 Query: 205 QRKA 208 KA Sbjct: 111 LHKA 114
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 134 bits (339), Expect = 7e-38 Identities = 62/222 (27%), Positives = 106/222 (47%), Gaps = 21/222 (9%) Query: 38 WDYLGKPVSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQS-EKMAYL 96 ++ +P+ L+ + + +G +II++T IVR I+ PL KA Y S KM L Sbjct: 333 LWFISQPLFKLLKWIHSFVG-NWGFSIIIITFIVRGIMYPLT-----KAQYTSMAKMRML 386 Query: 97 KPFFEPINQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVA 156 +P + + +R+ + +K E+MA + VNPLGG C PLLIQMP F A+Y Sbjct: 387 QPKIQAMRERLGD-----DKQRISQEMMALYKAEKVNPLGG--CFPLLIQMPIFLALYYM 439 Query: 157 VQFTKGVSTSTFMG----IDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLY 212 + + + + F + +L ++ F +S V + + ++ Sbjct: 440 LMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPM---QQKIMT 496 Query: 213 TMPIMMIVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPR 254 MP++ V + P+GL LY++V +IIQQ + L+ R Sbjct: 497 FMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKR 538
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.3 bits (78), Expect = 0.002 Identities = 27/169 (15%), Positives = 52/169 (30%), Gaps = 16/169 (9%) Query: 2 ALTDFKDDEQRRQQQKSFKEKILAE----LEKANQIRKEKEEELFKKDLEVQEAARRTAQ 57 A + + Q + + + E EKEE+ + + QE + T+Q Sbjct: 1069 AKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQ 1128 Query: 58 LYAEYKRQEAL--------SNNPKQASDIAAASQETTSTASTA---HTSAIKLEETAVAT 106 + + ++ E + N+P + TT+ +S ++ T T Sbjct: 1129 VSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTT 1188 Query: 107 GDQALSPPEEPALSESLLKE-EASVEGQTKKGGPVRRKTSKRQQTDRMA 154 + S E P + + + E K RR A Sbjct: 1189 VNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPA 1237
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.9 bits (80), Expect = 5e-05 Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 3/76 (3%) Query: 66 RLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIGTALLAAMKDLAVAQDRLGIILTC 125 LE++ + GY I ++VA Y+K+G+GTALL + A G++L Sbjct: 71 YLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLET 130 Query: 126 HDYLIP---YYEMNGF 138 D I +Y + F Sbjct: 131 QDINISACHFYAKHHF 146
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 37.1 bits (86), Expect = 1e-04 Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 8/87 (9%) Query: 46 GVTRDRIYTTGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEG 105 G+T T+ +W N + ++IDT G D F+ ++ ++ D + ++S K+G Sbjct: 53 GITIQTGITSFQWENTKVNIIDTPGHMD----FLAEVYR----SLSVLDGAILLISAKDG 104 Query: 106 VTDADEYVSKLLYRTNKPVILVVNKVD 132 V + L + P I +NK+D Sbjct: 105 VQAQTRILFHALRKMGIPTIFFINKID 131
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.5 bits (74), Expect = 0.007 Identities = 37/237 (15%), Positives = 76/237 (32%), Gaps = 20/237 (8%) Query: 183 GQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGAGNLSSGIAAYTAGVGQLDTAGLGQ 242 G+ + G V+ + + L + ++SS ++ Y ++ L + Sbjct: 115 GESVRKGDVLLKLT-ALGAEADTLKTQSSLLQARLEQ------TRYQILSRSIELNKLPE 167 Query: 243 LAADMPAYLDGVS------RLSKGANQLNAGLTQLALGSDLSQDKQANIQALMASLPKLN 296 L Y VS S Q + Q K+A ++A + + Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 297 QAIQQLKTNLSLSLAPNVDSGAIAKH-LADMTRLVQELVVDDTADKNN----QLAALQAT 351 + K+ L + + AIAKH + + E V + K+ + L A Sbjct: 228 NLSRVEKSRLD-DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAK 286 Query: 352 ATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSEELEAMSTSAGVADQLR 408 YQ + + E+ + T+ + L + + + + QL+ Sbjct: 287 EEYQLVTQLFKNEILDKLRQTTDNIG-LLTLELAKNEERQQASVIRAPVSVKVQQLK 342
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 49.6 bits (118), Expect = 8e-10 Identities = 15/53 (28%), Positives = 30/53 (56%) Query: 4 RKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSFYTHYKDKYEMID 56 Q+T++ IL+ + L + + ++AK AG++R + Y H+KDK ++ Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 25.2 bits (55), Expect = 0.031 Identities = 9/28 (32%), Positives = 12/28 (42%) Query: 7 DVAKMKKIKEDIKAHEGQLVELTLENGR 34 + A +K DI A E L L+N Sbjct: 38 EKADKQKAVSDIVALENALDMYKLDNHH 65
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 29.9 bits (67), Expect = 0.032 Identities = 15/35 (42%), Positives = 20/35 (57%) Query: 369 FTAGQTNGTSGYEEAAGQGLVAGINAALKVQGKPE 403 + G+ NG + Y GLV G+N AL+ QGK E Sbjct: 143 YMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNE 177