PredictBias

		>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature.

		          Length = 544

		

		 Score =  251 bits (643), Expect = 2e-78

		 Identities = 131/528 (24%), Positives = 200/528 (37%), Gaps = 99/528 (18%)

		

		Query: 79  GDTYIRYQQKYEGIPVIGTQVVV-KQPKAVTGFAATSRSASTATATRISLAKDLDVDLVA 137

		           G T +R++Q       +G  +V       ++  + T             L  +LD   + 

		Sbjct: 87  GHTVMRFEQAIAASLCMGAVLVAHVNDGELSSLSGT-------------LIPNLDKRTLK 133

		

		Query: 138 T---VSADDAKAFAKQQFEKDYSGTQVADDSIKSTK-EIRIVDNKAQLYYRVTFNASNTA 193

		           T   +S   A+  AKQ      +  + A +  K T+  I   +   +L Y V        

		Sbjct: 134 TEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTRLVIYPDEETPRLAYEVNVR---FL 190

		

		Query: 194 GGKPYRMVYIINA-TGTSKAMVLSFWDSI--PNYSDTGPGGNEKTVQYGPTGVKFFYGEN 250

		              P   +Y+I+A  G     VL+ W+ +         P     TV  G  GV       

		Sbjct: 191 TPVPGNWIYMIDAADGK----VLNKWNQMDEAKPGGAQPVAGTSTVGVG-RGV------- 238

		

		Query: 251 NLPALNVSEDNSTCTMDNGDVRLVNVEHQAD----HSWDSDYNTTAYQYSCGHNQGDPIN 306

		                 + +     T  +       ++         ++D    T                

		Sbjct: 239 ------LGDQKYINTTYSSYYGYYYLQDNTRGSGIFTYDGRNRTVLPGSLWADGDNQFFA 292

		

		Query: 307 GAYSPTDDAYYFGSMIIDMYKNWYGVDALQENGEPMQLIMRVHYGTDYDNAFWDGHTMSF 366

		              +   DA+Y+  ++ D YKN +G  +   +G    +   VHYG  Y+NAFW+G  M +

		Sbjct: 293 SYDAAAVDAHYYAGVVYDYYKNVHGRLSY--DGSNAAIRSTVHYGRGYNNAFWNGSQMVY 350

		

		Query: 367 GDG--SSFYPLV-SLDVAGHEVSHGFTEQHSGLDYKYQYGSLNEAFSDMAGQAVRAYLLS 423

		           GDG   +F P    +DV GHE++H  T+  +GL Y+ + G++NEA SD+ G  V  Y   

		Sbjct: 351 GDGDGQTFLPFSGGIDVVGHELTHAVTDYTAGLVYQNESGAINEAMSDIFGTLVEFYANR 410

		

		Query: 424 TNPDLYKQLYFNQDEVTWGIGETISKGDDESDALRYMNNPSKDGVSADCDDKELAGSTCT 483

		            NPD             W IGE I       DALR M++P+K G                

		Sbjct: 411 -NPD-------------WEIGEDIYTPGVAGDALRSMSDPAKYGDPDH------------ 444

		

		Query: 484 ISYDEVVATSKDYPIKDRQSYIVHTGSGVFNKAFYLLSQQ----------VGIKDAFRVM 533

		             Y +    ++D          VHT SG+ NKA YLLSQ           +G     ++ 

		Sbjct: 445 --YSKRYTGTQDNG-------GVHTNSGIINKAAYLLSQGGVHYGVSVTGIGRDKMGKIF 495

		

		Query: 534 KDANVKYWGKYSDFSDAACGVLKAAND---DGVGSTSMIKDVFNQVGV 578

		             A V Y    S+FS      ++AA D         + +K  FN VGV

		Sbjct: 496 YRALVYYLTPTSNFSQLRAACVQAAADLYGSTSQEVNSVKQAFNAVGV 543

		

		

		>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein

		           signature.

		          Length = 522

		

		 Score = 28.2 bits (62), Expect = 0.045

		 Identities = 26/117 (22%), Positives = 49/117 (41%), Gaps = 5/117 (4%)

		

		Query: 26  LIFSQQDPKLFGRMQHYFQYIMKANLARLDQAEQTEQALNETKATLL-----VEKKQLER 80

		           L  +  +P+     ++  + I +     LDQ E+ E    + +A  L     + KKQ E 

		Sbjct: 183 LTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEE 242

		

		Query: 81  LIKQQEIDLKKLSNDKQLKDQLVTIISTSINEKSKRLVDLYKNEKRLLALIEQLDQE 137

		            ++Q+  D   +  DK  K      I  S ++ + R   + +  K L   I ++ Q+

		Sbjct: 243 AVRQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQK 299

		

		

		>FbpA_PF05833#Fibronectin-binding protein

		          Length = 577

		

		 Score = 24.1 bits (52), Expect = 0.027

		 Identities = 6/31 (19%), Positives = 9/31 (29%)

		

		Query: 6   IKKTKQELKNLELKLKNKSEELTSSEKIDKY 36

		            K     +     K K  +  L   E  D +

		Sbjct: 305 QKIVMNNINRCTKKDKILNNTLKKCEDKDIF 335

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score =  742 bits (1918), Expect = 0.0

		 Identities = 283/1032 (27%), Positives = 501/1032 (48%), Gaps = 32/1032 (3%)

		

		Query: 3    LPDFCIKNPVITVVISLVIILLGLIAYTRLSITGYPNISLPQVGVHTTLSGASASYMENQ 62

		            + +F I+ P+   V+++++++ G +A  +L +  YP I+ P V V     GA A  +++ 

		Sbjct: 1    MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60

		

		Query: 63   VSAVIEAQLANLTGVDFVESSSQP-GVSDVLLQFKHGVNINQKVNEISNALAKVSSRLPH 121

		            V+ VIE  +  +  + ++ S+S   G   + L F+ G + +    ++ N L   +  LP 

		Sbjct: 61   VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120

		

		Query: 122  GIVGPEVHAANPNETPIISVFIADDKHNIT--YLTDYIKRYIQPQLQRISGVATVNASGS 179

		             +    +     + + ++      D    T   ++DY+   ++  L R++GV  V   G+

		Sbjct: 121  EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180

		

		Query: 180  HNYAVRMWLEPAKMATLQVTVEDVINAIKSQNTLSQNGEIKTT------SRTYPLIPDAR 233

		              YA+R+WL+   +   ++T  DVIN +K QN     G++  T           +I   R

		Sbjct: 181  -QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239

		

		Query: 234  INRVNDFNHLIISHSQN-KNIRFDNIGSVGLGSDNNQSFSTYDGKKGVSIGVVPASNANP 292

		                 +F  + +  + +   +R  ++  V LG +N    +  +GK    +G+  A+ AN 

		Sbjct: 240  FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299

		

		Query: 293  LEVAQSVYQSVKMLEEHLPEGMSIKVAYDLSLFLQSSIDSVYESLWVAAALVVLIVFIFL 352

		            L+ A+++   +  L+   P+GM +   YD + F+Q SI  V ++L+ A  LV L++++FL

		Sbjct: 300  LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359

		

		Query: 353  GSLRASLIPLLTLPICLIGTFFFIYLFGFTLNIISLLALVLAIGLIVDDAIVILENSYRY 412

		             ++RA+LIP + +P+ L+GTF  +  FG+++N +++  +VLAIGL+VDDAIV++EN  R 

		Sbjct: 360  QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419

		

		Query: 413  IQS-GLPARQAAFKGTNEVVWPVIAISLTLVAVYAPLGLSQGLTGQLFWQFALTLIIAVV 471

		            +    LP ++A  K  +++   ++ I++ L AV+ P+    G TG ++ QF++T++ A+ 

		Sbjct: 420  MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479

		

		Query: 472  LSSLVALTLAPMLCAYWL-------SEKENKFQQNISSVLNYLSVRYRLILSYCLSHRKV 524

		            LS LVAL L P LCA  L        E +  F    ++  ++    Y   +   L     

		Sbjct: 480  LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539

		

		Query: 525  IIAGFIFILIAGYGSYRQLPSELAPVTDQGYINIHFNGPTNVSASDMQSHVKSLGAVFAK 584

		             +  +  I+      + +LPS   P  DQG        P   +    Q  +  +   + K

		Sbjct: 540  YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599

		

		Query: 585  QS--NVSHFLINSGEPNTSQGQ----ATLLLKPWGER---KQSQEEISQQLAGKLSQIP- 634

		                NV      +G   + Q Q    A + LKPW ER   + S E +  +   +L +I  

		Sbjct: 600  NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659

		

		Query: 635  GINAVIAPPPPLGIDGQGGFSLELVLMTPRSYQYLNQVATDLLKNLAHAPG-LQGVTTNV 693

		            G       P  + +    GF  EL+      +  L Q    LL   A  P  L  V  N 

		Sbjct: 660  GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719

		

		Query: 694  KWDNFEYRAQVNRALAADLGVDTAEVTNTLSVLMGGYQAGDYYYNGYPYDIILQALPNHV 753

		              D  +++ +V++  A  LGV  +++  T+S  +GG    D+   G    + +QA     

		Sbjct: 720  LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779

		

		Query: 754  AQLSDLQNIYVKTASDTMVPVSTLVNITQSTEPTVLANYNQLHSLHIMANLKSGVSMSDA 813

		                D+  +YV++A+  MVP S             L  YN L S+ I      G S  DA

		Sbjct: 780  MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839

		

		Query: 814  ISKISTICNKFLPDDVSYQFFGQTKSFLSSKNDMAENFILAIIFIYLFLAAQFGCFIQPL 873

		            ++ +  + +K LP  + Y + G +     S N       ++ + ++L LAA +  +  P+

		Sbjct: 840  MALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPV 898

		

		Query: 874  IILTAVPVAMAGAIFALSLTKGSLNLFSEIGLITLVGLISKHGILIIDIANK-KLAEGYD 932

		             ++  VP+ + G + A +L     +++  +GL+T +GL +K+ ILI++ A      EG  

		Sbjct: 899  SVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKG 958

		

		Query: 933  KFEAILEAAQLRLRPILMTTMTMVLGALPLIFHGGAGAESRMQLGIVIVGGLVFGTLCTL 992

		              EA L A ++RLRPILMT++  +LG LPL    GAG+ ++  +GI ++GG+V  TL  +

		Sbjct: 959  VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAI 1018

		

		Query: 993  VVVPVFYSLFST 1004

		              VPVF+ +   

		Sbjct: 1019 FFVPVFFVVIRR 1030

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 50.2 bits (120), Expect = 6e-09

		 Identities = 35/188 (18%), Positives = 73/188 (38%), Gaps = 24/188 (12%)

		

		Query: 103 QADLSSAQAKYAAYDKRYKRFVYLKKFGDVSDQDLEAAYINLRSYQAEMDKLKVLIAQTV 162

		           ++++ SA+ +Y    + +K         ++ D+ L     N+     E+ K +     +V

		Sbjct: 279 ESEILSAKEEYQLVTQLFKN--------EILDK-LRQTTDNIGLLTLELAKNEERQQASV 329

		

		Query: 163 IKAPFSGRLGKSQI-VVGSYVDAGSTLVKLV-DTEQLLASYNVPGEYYPQLRTQQVVTVA 220

		           I+AP S ++ + ++   G  V    TL+ +V + + L  +  V  +    +   Q   + 

		Sbjct: 330 IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIK 389

		

		Query: 221 SDAYP---NHLFQGNTQFISPIIAADTNTVLV----------QALIDNPDHKLTAGMYVK 267

		            +A+P        G  + I+     D    LV               N +  L++GM V 

		Sbjct: 390 VEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVT 449

		

		Query: 268 IQQNIGKK 275

		            +   G +

		Sbjct: 450 AEIKTGMR 457

		

		

		

		 Score = 44.4 bits (105), Expect = 5e-07

		 Identities = 16/53 (30%), Positives = 24/53 (45%)

		

		Query: 63  AKNQVEIASQMAGLVKHIYFHSGQSVQQGTVLVKLDDGVYQADLSSAQAKYAA 115

		           +    EI      +VK I    G+SV++G VL+KL     +AD    Q+    

		Sbjct: 93  SGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQ 145

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  100 bits (249), Expect = 2e-27

		 Identities = 68/232 (29%), Positives = 100/232 (43%), Gaps = 16/232 (6%)

		

		Query: 4   ILITGATSGFGRATAELFADKGWSLILTGRRTQYLNDLYS--KLHSKTAIHTITLDVRDT 61

		             ITGA  G G A A   A +G  +       + L  + S  K  ++ A      DVRD+

		Sbjct: 11  AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHA-EAFPADVRDS 69

		

		Query: 62  DQVFQTLSELPPPFKEIDVLINNAGLALGLETADQANLSDWHQMIETNITGLVNVTRAVL 121

		             + +  + +      ID+L+N AG+ L        +  +W      N TG+ N +R+V 

		Sbjct: 70  AAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128

		

		Query: 122 PQMKAINRGYIINISSIAANTPYIGGNVYGATKAFVDQFTKNLRTDLLGTKIRATTIAPG 181

		             M     G I+ + S  A  P      Y ++KA    FTK L  +L    IR   ++PG

		Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188

		

		Query: 182 LAETEFSMVRFKGDKNRAEQVYKD----------LKPLA-AEDIANTIDWLV 222

		             ET+     +  D+N AEQV K           LK LA   DIA+ + +LV

		Sbjct: 189 STETDMQWSLWA-DENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score =  154 bits (391), Expect = 1e-46

		 Identities = 79/354 (22%), Positives = 142/354 (40%), Gaps = 54/354 (15%)

		

		Query: 1   MKQLLVTGGAGFIGCNFVRYMLKTYNHVNIINVDKLT--YAGSLNNLKN-LPDESRHIFV 57

		           MK  LVTG AGFIG +  + +L+  + V  + +D L   Y  SL   +  L  +    F 

		Sbjct: 1   MK-YLVTGAAGFIGFHVSKRLLEAGHQV--VGIDNLNDYYDVSLKQARLELLAQPGFQFH 57

		

		Query: 58  QGDICDRPFIDQLLREYDIDTVVNFAAESHVDNSIKNPKPFIETNINGTFTLLEAARQFW 117

		           + D+ DR  +  L      + V        V  S++NP  + ++N+ G   +LE  R   

		Sbjct: 58  KIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK 117

		

		Query: 118 LEEKQWLKSDCRFHHVSTDEVYGTLSKGEPAFTEATAYAPNSPYSASKAGSDHLVRAYFH 177

		           ++            + S+  VYG L++  P  T+ +   P S Y+A+K  ++ +   Y H

		Sbjct: 118 IQ---------HLLYASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH 167

		

		Query: 178 TYGLPMTISNCSNNYGPYQHREKLIPTVIHLCLAEKKIPIYGNGSNIRDWLYVEDHCSAI 237

		            YGLP T       YGP+   +  +       L  K I +Y  G   RD+ Y++D   AI

		Sbjct: 168 LYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAI 227

		

		Query: 238 DKILHNGRL------------------GEVYNIGANNEADNLTLVKQICQILDKK----- 274

		            ++                          VYNIG ++  + +  ++ +   L  +     

		Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNM 287

		

		Query: 275 QPRKNGNSYQELITFVIDRAGHDWRYAIDNRKIKNELNWQPVYSLQGALELLIN 328

		            P + G+  +                A D + +   + + P  +++  ++  +N

		Sbjct: 288 LPLQPGDVLET--------------SA-DTKALYEVIGFTPETTVKDGVKNFVN 326

		

		

		>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein

		          signature.

		          Length = 166

		

		 Score = 43.3 bits (102), Expect = 4e-08

		 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 6/53 (11%)

		

		Query: 8  GTFDLFHYGHLRILERARALGDKLIVGVSSDALNYNKKQCYPITPQEQRLSIV 60

		          G+FD   +GHL I+ER   L D++ V V     N NK+   P+   ++RL  +

		Sbjct: 7  GSFDPITFGHLDIIERGCRLFDQVYVAV---LRNPNKQ---PMFSVQERLEQI 53

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score =  219 bits (559), Expect = 9e-72

		 Identities = 89/326 (27%), Positives = 136/326 (41%), Gaps = 33/326 (10%)

		

		Query: 2   YLVTGGAGFIGSHTVELLLAQGYKVRVLDNLSTGKLSNLPAD------QSNLEVITADVR 55

		           YLVTG AGFIG H  + LL  G++V  +DNL+     +L         Q   +    D+ 

		Sbjct: 3   YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62

		

		Query: 56  DYGAV--LQGLQGVSAVLHLAAQVSVPRSIDKPLESLDVNTKGFINVLEAVRRTDDKIHV 113

		           D   +  L        V     +++V  S++ P    D N  GF+N+LE  R    + H+

		Sbjct: 63  DREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ-HL 121

		

		Query: 114 AYASSAAVYGSAEQLPCDDTQILPVEINSFYALEKANKERYAALYHKLFNITSTGLRYFN 173

		            YASS++VYG   ++P      +   + S YA  K   E  A  Y  L+ + +TGLR+F 

		Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPV-SLYAATKKANELMAHTYSHLYGLPATGLRFFT 180

		

		Query: 174 VFGPKQDPSSQYAGVISKFMTAAANDQPISIYGDGEQSRDFIYVTDVARANMLALQNT-- 231

		           V+GP   P         KF  A    + I +Y  G+  RDF Y+ D+A A +        

		Sbjct: 181 VYGPWGRPDMAL----FKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPH 236

		

		Query: 232 -----------------QHGVCNIATGCATSLNQLVNGIEKITGNKLNCSYFYERPGDIK 274

		                             + V NI       L   +  +E   G +   +    +PGD+ 

		Sbjct: 237 ADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVL 296

		

		Query: 275 HSIASIYHADELLNFLAKIKFSDGLK 300

		            + A      E++ F  +    DG+K

		Sbjct: 297 ETSADTKALYEVIGFTPETTVKDGVK 322

		

		

		>OMPADOMAIN#OMPA domain signature.

		          Length = 346

		

		 Score =  115 bits (288), Expect = 1e-31

		 Identities = 75/359 (20%), Positives = 135/359 (37%), Gaps = 62/359 (17%)

		

		Query: 1   MKISKVACSLAVAVLALPLASFAVSQSGQFFATPSIGSGWFDSDRQVS-------NEPVL 53

		           MK  K A ++AVA+      + A  +   ++    +G   +     ++       N+   

		Sbjct: 1   MK--KTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGA 58

		

		Query: 54  NLSLGYNITDNIAVALSY---AHASNKDDVTGNSASMNQMRIDGLYRFMAKSPLQPYLLA 110

		               GY +   +   + Y        K  V   +     +++     +     L  Y   

		Sbjct: 59  GAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRL 118

		

		Query: 111 GIG------RQNLKGSNSFLD----YGVGLTYDFMPNVALDVGVRRQYQLGTYH-----R 155

		           G        + N+ G N        +  G+ Y   P +A  +  +    +G  H      

		Sbjct: 119 GGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRP 178

		

		Query: 156 NDTIAAVGIQFSFGPHGSAFSADESFDQNEIAPAPMPEQAAPPAPAPEAAAPVNPCAVPV 215

		           ++ + ++G+ + FG                      P  A  PAPAPE            

		Sbjct: 179 DNGMLSLGVSYRFG-----------------QGEAAPVVAPAPAPAPEVQTKHF-----T 216

		

		Query: 216 NEVAISFASASDMVSSKYDCQLSRIAAFLS-VNPKS-SAMIKGYADSSGSPNYNNQGLSQ 273

		            +  + F      +  +    L ++ + LS ++PK  S ++ GY D  GS  YN QGLS+

		Sbjct: 217 LKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYN-QGLSE 275

		

		Query: 274 RRAESVKDYLVTQKSINSHRLITQALGTENPVATNKT---------VEGRAKNRRVDVT 323

		           RRA+SV DYL++ K I + ++  + +G  NPV  N           ++  A +RRV++ 

		Sbjct: 276 RRAQSVVDYLIS-KGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIE 333

		

		

		>V8PROTEASE#V8 serine protease family signature.

		          Length = 336

		

		 Score = 63.9 bits (155), Expect = 2e-13

		 Identities = 40/199 (20%), Positives = 70/199 (35%), Gaps = 44/199 (22%)

		

		Query: 97  LGSGVIMDKSGYIITNYHVIRNADKIDVALH------------DGRKAKARVIGTDPEVD 144

		           + SGV++ K   ++TN HV+        AL             +G     ++     E D

		Sbjct: 103 IASGVVVGK-DTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGD 161

		

		Query: 145 LAILKINLKDL---------PVIKVNKESSAVGDVVLAIGNPYGVGQTITQGIVSALGRT 195

		           LAI+K +  +          P    N   + V   +   G P           V+ +  +

		Sbjct: 162 LAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-------KPVATMWES 214

		

		Query: 196 RLRITNY-DNLIQTDAAVNPGNSGGALVNSRGQLVGINTAIFSRTGGFDGIGFAIP---- 250

		           + +IT      +Q D +   GNSG  + N + +++GI+           G+         

		Sbjct: 215 KGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFNGAVF 265

		

		Query: 251 -VSTVENVLAQIVKTGHVT 268

		               V N L Q ++  H  

		Sbjct: 266 INENVRNFLKQNIEDIHFA 284

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 85.7 bits (212), Expect = 2e-21

		 Identities = 30/132 (22%), Positives = 58/132 (43%), Gaps = 1/132 (0%)

		

		Query: 3   KVLMVDDDQELCQLVQTFFTKHFLDIDAVHTGAAAVEKVKQGQYDAMILDQNLPDIHGLE 62

		            +L+ DDD  +  ++    ++   D+      A     +  G  D ++ D  +PD +  +

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64

		

		Query: 63  LCEKLRKHYQG-PVLILSGEGGEVARVLGLRAGADDYLEKPFSRHELLERMRKLIERCGR 121

		           L  +++K     PVL++S +   +  +     GA DYL KPF   EL+  + + +    R

		Sbjct: 65  LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124

		

		Query: 122 SAHALRAAPEEG 133

		               L    ++G

		Sbjct: 125 RPSKLEDDSQDG 136

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score =  792 bits (2047), Expect = 0.0

		 Identities = 309/1030 (30%), Positives = 524/1030 (50%), Gaps = 28/1030 (2%)

		

		Query: 5    DIFVRRPVLASVVSIMILILGLRALFELQVRQYPKIENTVITVTTTYSGASASLIQGFIT 64

		            + F+RRP+ A V++I++++ G  A+ +L V QYP I    ++V+  Y GA A  +Q  +T

		Sbjct: 3    NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62

		

		Query: 65   SPIEKAVASVDGIDYISAQSV-TSTSTISIYLKPNVNADAAFTQVMSQVNSVQNQLPQDA 123

		              IE+ +  +D + Y+S+ S    + TI++  +   + D A  QV +++      LPQ+ 

		Sbjct: 63   QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122

		

		Query: 124  DQPVIAKQKSDSVALLYISYSSN--ELTSPQIYDYLSRVIQPKLQTVQGVGSASILGGNP 181

		             Q  I+ +KS S  L+   + S+    T   I DY++  ++  L  + GVG   + G   

		Sbjct: 123  QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA-Q 181

		

		Query: 182  FAMRVWLNPIRMAALHVTASDVSSALTANNYQTAAGQTKGVFSV------YNISAKTDIN 235

		            +AMR+WL+   +    +T  DV + L   N Q AAGQ  G  ++       +I A+T   

		Sbjct: 182  YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241

		

		Query: 236  TVKDFKNIVVKGDGD-TLIHLEDIAKVELGSEDYSSSVIFNGKRGVFMAIQSTASANPLS 294

		              ++F  + ++ + D +++ L+D+A+VELG E+Y+     NGK    + I+    AN L 

		Sbjct: 242  NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301

		

		Query: 295  VIKDVRKVLPELTKDLPPSLKQNVVYDATRYINASIQEVIKTIIEATAIVIVVIFLFLGS 354

		              K ++  L EL    P  +K    YD T ++  SI EV+KT+ EA  +V +V++LFL +

		Sbjct: 302  TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361

		

		Query: 355  LRSVVIPVITIPLSLIGVCSLMLIFGYSINLLTLFAMVLAIGLVVDDAIIVVENVHRHIE 414

		            +R+ +IP I +P+ L+G  +++  FGYSIN LT+F MVLAIGL+VDDAI+VVENV R + 

		Sbjct: 362  MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421

		

		Query: 415  EGK-QPFDAALIGAREIASPVIAMTITLAAVYAPIAFVGGITGALFKEFALTLAAAVIVS 473

		            E K  P +A      +I   ++ + + L+AV+ P+AF GG TGA++++F++T+ +A+ +S

		Sbjct: 422  EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481

		

		Query: 474  GVIALTLSPMMCSKLLVAD-----NANGGLAHWLDRQFLRLQQRYERILHHTLEHRPVVL 528

		             ++AL L+P +C+ LL           GG   W +  F      Y   +   L      L

		Sbjct: 482  VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541

		

		Query: 529  TFGLIILVGIFGMLKMTQKQLAPHEDQGFLITFASAPKYANINYVEKYSEEFAKIYKSFP 588

		                +I+ G+  +         P EDQG  +T    P  A     +K  ++    Y    

		Sbjct: 542  LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601

		

		Query: 589  AIADYFIINTTGAGTFPSQVTSG---AVLKPWRDRSM---TTMQLQPLLQHKLNQITGLQ 642

		                  +    G         +G     LKPW +R+    +   +    + +L +I    

		Sbjct: 602  KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661

		

		Query: 643  AQAIQMPALPGPD---GMPIQFVLTSTADYSVLNNVMTKFKAAADKSGLFLFS-SSDLKF 698

		                 MPA+       G   + +  +   +  L     +    A +    L S   +   

		Sbjct: 662  VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721

		

		Query: 699  NKPKLNIAIDRAKAAQMGITMQQIGSTLSTLLSGGKVNYFSLDGRSYKVIPQLADNERLT 758

		            +  +  + +D+ KA  +G+++  I  T+ST L G  VN F   GR  K+  Q     R+ 

		Sbjct: 722  DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781

		

		Query: 759  PQQLNNNYIKTAAGALIPLSTLITLSTSIEPGTLNQFQQLNSATLSAVAMPGHTDTEALN 818

		            P+ ++  Y+++A G ++P S   T         L ++  L S  +   A PG +  +A+ 

		Sbjct: 782  PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841

		

		Query: 819  FLKAQATKLMPKGMSYNFSGQSRTLVQEGNALIYTFFFALIMIFLVLAAQFESFRDPFII 878

		             ++  A+KL P G+ Y+++G S      GN        + +++FL LAA +ES+  P  +

		Sbjct: 842  LMENLASKL-PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900

		

		Query: 879  MFTVPMAIFGAAIPMAFGWTSLNIYTEIGLVTLIGLITKHGILMVQFANDLQEQEGRDIR 938

		            M  VP+ I G  +         ++Y  +GL+T IGL  K+ IL+V+FA DL E+EG+ + 

		Sbjct: 901  MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960

		

		Query: 939  SAIEHAAGMRLRPILMTTAAMVVGVLPLIIASGAGAVSRHDLGLVIAMGLLIGTLFTLFV 998

		             A   A  MRLRPILMT+ A ++GVLPL I++GAG+ +++ +G+ +  G++  TL  +F 

		Sbjct: 961  EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020

		

		Query: 999  IPTMYTYLTK 1008

		            +P  +  + +

		Sbjct: 1021 VPVFFVVIRR 1030

		

		

		

		 Score = 88.7 bits (220), Expect = 6e-20

		 Identities = 53/317 (16%), Positives = 119/317 (37%), Gaps = 9/317 (2%)

		

		Query: 705  IAIDRAKAAQMGITMQQIGSTLST---LLSGGKVNYFSLDGRSYKVIPQLADNERLTPQQ 761

		            I +D     +  +T   + + L      ++ G++               +A      P++

		Sbjct: 186  IWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEE 245

		

		Query: 762  LNNNYIKTAA-GALIPLSTLITLSTSIEP-GTLNQFQQLNSATLSAVAMPGHTDTEALNF 819

		                 ++  + G+++ L  +  +    E    + +     +A L      G    +    

		Sbjct: 246  FGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKA 305

		

		Query: 820  LKAQATKL---MPKGMSYNFSGQSRTLVQEG-NALIYTFFFALIMIFLVLAAQFESFRDP 875

		            +KA+  +L    P+GM   +   +   VQ   + ++ T F A++++FLV+    ++ R  

		Sbjct: 306  IKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRAT 365

		

		Query: 876  FIIMFTVPMAIFGAAIPMAFGWTSLNIYTEIGLVTLIGLITKHGILMVQFANDLQEQEGR 935

		             I    VP+ + G    +A    S+N  T  G+V  IGL+    I++V+    +  ++  

		Sbjct: 366  LIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKL 425

		

		Query: 936  DIRSAIEHAAGMRLRPILMTTAAMVVGVLPLIIASGAGAVSRHDLGLVIAMGLLIGTLFT 995

		              + A E +       ++     +    +P+    G+         + I   + +  L  

		Sbjct: 426  PPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVA 485

		

		Query: 996  LFVIPTMYTYLTKQRTP 1012

		            L + P +   L K  + 

		Sbjct: 486  LILTPALCATLLKPVSA 502

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 50.6 bits (121), Expect = 5e-09

		 Identities = 33/175 (18%), Positives = 64/175 (36%), Gaps = 22/175 (12%)

		

		Query: 116 AKLKLDQLTYDRDRSLLKKNAISRQDVDTALTSLEQTKAQMLATEVSISQKLIRAPFSGK 175

		           AK +   +T      +L K   +  ++      L + + +  A+        IRAP S K

		Sbjct: 285 AKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASV-------IRAPVSVK 337

		

		Query: 176 IGIRNVN-LGQYISPGTNIVSLQSIN-PLHVNFSLPQEDMNKIKLGQKISAHVDTFAGRE 233

		           +    V+  G  ++    ++ +   +  L V   +  +D+  I +GQ     V+ F    

		Sbjct: 338 VQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTR 397

		

		Query: 234 F---TGTITAMNSE--VDSNT-------RTIEIQASLPNPKH-ELYPGMFTTVQV 275

		           +    G +  +N +   D           +IE        K+  L  GM  T ++

		Sbjct: 398 YGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEI 452

		

		

		

		 Score = 49.4 bits (118), Expect = 1e-08

		 Identities = 22/100 (22%), Positives = 42/100 (42%), Gaps = 2/100 (2%)

		

		Query: 74  VTSQVSGQVERILFQSGDFVEKGRPLVQLDDRTEQANLLQYKAKLKLDQLTYDRDRSLLK 133

		           +    +  V+ I+ + G+ V KG  L++L     +A+ L+ ++ L   +L   R + L +

		Sbjct: 99  IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158

		

		Query: 134 KNAISRQDVDTALTSLEQTKAQMLATEVSISQKLIRAPFS 173

		             +I    +       E     +   EV     LI+  FS

		Sbjct: 159 --SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS 196

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 33.3 bits (76), Expect = 8e-04

		 Identities = 7/81 (8%), Positives = 27/81 (33%), Gaps = 4/81 (4%)

		

		Query: 1   MLAEERQMIESLGTRLHEAGTKIEKDQEAAALIEEKISSQKDAVYQLTQATLLQEHALGQ 60

		              ++   ++           +I + +  + + + ++         L     + +HA+ +

		Sbjct: 201 QKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFS----SLLHKQAIAKHAVLE 256

		

		Query: 61  AQQQIAQLRAELAEQHQQATE 81

		            + +  +   EL     Q  +

		Sbjct: 257 QENKYVEAVNELRVYKSQLEQ 277

		

		

		

		 Score = 30.6 bits (69), Expect = 0.006

		 Identities = 16/83 (19%), Positives = 32/83 (38%), Gaps = 9/83 (10%)

		

		Query: 1   MLAEERQMIESLGTRLHEAGTKIEKDQEAAALIEEKISSQKDAVYQLTQATLLQEHALGQ 60

		           +L +E + +E     L    +++E+ +      +E+       +++           L Q

		Sbjct: 254 VLEQENKYVE-AVNELRVYKSQLEQIESEILSAKEEYQ-LVTQLFKNEILD-----KLRQ 306

		

		Query: 61  AQQQIAQLRAEL--AEQHQQATE 81

		               I  L  EL   E+ QQA+ 

		Sbjct: 307 TTDNIGLLTLELAKNEERQQASV 329

		

		

		

		 Score = 28.3 bits (63), Expect = 0.033

		 Identities = 10/64 (15%), Positives = 23/64 (35%)

		

		Query: 15  RLHEAGTKIEKDQEAAALIEEKISSQKDAVYQLTQATLLQEHALGQAQQQIAQLRAELAE 74

		           R       IE ++     + ++   Q  +  ++ + T L +      Q Q  Q    L +

		Sbjct: 152 RYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211

		

		Query: 75  QHQQ 78

		           +  +

		Sbjct: 212 KRAE 215

		

		

		>TYPE3OMGPROT#Type III secretion system outer membrane G protein

		           family signature.

		          Length = 607

		

		 Score = 27.9 bits (62), Expect = 0.017

		 Identities = 16/72 (22%), Positives = 26/72 (36%), Gaps = 8/72 (11%)

		

		Query: 68  VTGEENASI-SIDY-------PDTVTLAGPASSSLTVDIQTNDENETLNGSGQLTKSFSG 119

		           VTG+E A +  I Y       P  +T    +  SL + I+  ++    +G   +      

		Sbjct: 385 VTGKEVAELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIEGIPTISRT 444

		

		Query: 120 EVTVNATTAAGD 131

		            V   A    G 

		Sbjct: 445 VVDTVARVGHGQ 456

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 33.3 bits (76), Expect = 0.003

		 Identities = 21/82 (25%), Positives = 32/82 (39%), Gaps = 18/82 (21%)

		

		Query: 189 VLMVGPPGTGKTLLAKAI---AGEAKVPFFS-----ISGSDFVEMFVGV------GASRV 234

		           +++ G  GTGK L+A+A+         PF +     I          G       GA   

		Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR 222

		

		Query: 235 RD-MFDQAKKRAPCIIFIDEID 255

		               F+QA+      +F+DEI 

		Sbjct: 223 STGRFEQAEGGT---LFLDEIG 241

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 38.3 bits (89), Expect = 9e-05

		 Identities = 19/77 (24%), Positives = 32/77 (41%)

		

		Query: 259 EVPSPVAGVVKEIKVAEGSKVSEGDLIVLVESPGASSVVVSSVTSQGAAAVAAPAANQPV 318

		           E+      +VKEI V EG  V +GD+++ + + GA +  + + +S   A +         

		Sbjct: 98  EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157

		

		Query: 319 TSAASAAAPVLTQASGP 335

		            S      P L     P

		Sbjct: 158 RSIELNKLPELKLPDEP 174

		

		

		

		 Score = 37.9 bits (88), Expect = 1e-04

		 Identities = 45/262 (17%), Positives = 98/262 (37%), Gaps = 21/262 (8%)

		

		Query: 48  EVPAPFAGTVKAIKVKEGSKVSEGSLIVQMEGSG-----DVVESATVPAAVAAPTAVVAP 102

		           E+       VK I VKEG  V +G +++++   G        +S+ + A +      +  

		Sbjct: 98  EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157

		

		Query: 103 TGPIEVRVPDIG--------NYSGVDVIEINVAVGDQVSE---EDALITLETDKATMEVP 151

		                 ++P++         N S  +V+ +   + +Q S    +     L  DK   E  

		Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217

		

		Query: 152 SPVAGIVKEIKVAEGSQVSEGDL-VLIVEGAGGTSAVA---HTPATAQQEVTTISSAVPM 207

		           + +A I +   ++   +    D   L+ + A    AV    +    A  E+    S +  

		Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277

		

		Query: 208 AVVATASVQEVHVPDIGNYSGVDVIEINVAVGDCVNEEDPLITLETDKATMEVPSPVAGV 267

		                 S +E +      +    + ++     +       L   E  +    + +PV+  

		Sbjct: 278 IESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVK 337

		

		Query: 268 VKEIKV-AEGSKVSEGDLIVLV 288

		           V+++KV  EG  V+  + ++++

		Sbjct: 338 VQQLKVHTEGGVVTTAETLMVI 359

		

		

		>PHPHLIPASEA1#Bacterial phospholipase A1 protein signature.

		          Length = 289

		

		 Score =  171 bits (434), Expect = 2e-53

		 Identities = 88/249 (35%), Positives = 133/249 (53%), Gaps = 17/249 (6%)

		

		Query: 82  NNSLGIIFYQPNYVLPYYYTGSPYQAIYNGQTPDNQKVMSSEFKAQLSLMVPLWKDMFGN 141

		           +N   +  Y  NY++    +    +AI +    +N +    E K QLSL  PLW+ + G 

		Sbjct: 47  DNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENAR--KDEVKFQLSLAFPLWRGILG- 103

		

		Query: 142 PDYSLNVGYTQLSYWQF--YAKSQYFRETNYEPELFV---TDHFHRNW---QISYGVVHQ 193

		           P+  L   YTQ S+WQ     +S  FRETNYEP+LF+   TD+    W    +  G  H 

		Sbjct: 104 PNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHD 163

		

		Query: 194 SNGRGGSLERSWNRAYLNLEASGEHWLASIKPWVLIFKPDSSDLHNPDIAHYLGHERIMF 253

		           SNGR     RSWNR Y  L A   +WL  +KPW ++   ++ D  NPDI  Y+G+ ++  

		Sbjct: 164 SNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVV--GNTDD--NPDITKYMGYYQLKI 219

		

		Query: 254 AYVFNNKMQASIALTNIESGMKRGAVELDYSFPLTKHINGFVQYFNGYGQSLIEYDHRTQ 313

		            Y   + + ++    N  +G   G  EL  S+P+TKH+  + Q ++GYG+SLI+Y+    

		Sbjct: 220 GYHLGDAVLSAKGQYNWNTG--YGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQT 277

		

		Query: 314 SVGIGIALS 322

		            VG+G+ L+

		Sbjct: 278 RVGVGVMLN 286

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 29.8 bits (67), Expect = 0.004

		 Identities = 7/30 (23%), Positives = 17/30 (56%)

		

		Query: 125 IEADKAGVVKQILLSDGDIVEFDQPLVIIE 154

		           I+  +  +VK+I++ +G+ V     L+ + 

		Sbjct: 99  IKPIENSIVKEIIVKEGESVRKGDVLLKLT 128

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 29.1 bits (65), Expect = 0.041

		 Identities = 29/145 (20%), Positives = 56/145 (38%), Gaps = 5/145 (3%)

		

		Query: 43  LGMSDVESFSVMGAFMALVYGFVSIGGYIGDRVLGTKRTMVFGAIVLAIGYFLLAASVDL 102

		                  +  V  AFM       ++ G + D+ LG KR ++FG I+   G  +       

		Sbjct: 44  FNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ-LGIKRLLLFGIIINCFGSVIGFVGHSF 102

		

		Query: 103 PQIIFIALGTICIGNGLFKANPSSLLSK-CYKEGDPKLDGAFTLYYMSINLGSFISMSLT 161

		             ++ +A      G   F A    ++++   KE   K   AF L    + +G  +  ++ 

		Sbjct: 103 FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGK---AFGLIGSIVAMGEGVGPAIG 159

		

		Query: 162 PTISEHFGWSMAYVVCGIGLVIALL 186

		             I+ +  WS   ++  I ++    

		Sbjct: 160 GMIAHYIHWSYLLLIPMITIITVPF 184

		

		

		>BONTOXILYSIN#Bontoxilysin signature.

		          Length = 1196

		

		 Score = 31.0 bits (70), Expect = 0.018

		 Identities = 24/137 (17%), Positives = 51/137 (37%), Gaps = 14/137 (10%)

		

		Query: 508 KKIKKLSNNYTKFVVNFNNLTISKLCSRENIQRILNNPSQYYNREHLILAKLISSFNARA 567

		           + ++    + +K  +  + L + +  + E     L+N SQ       I    + +F  +A

		Sbjct: 700 QIVQNKFTDLSKASIPPDTLKLIRETT-EKTFIDLSNESQ-------ISMNRVDNFLNKA 751

		

		Query: 568 IKGSRMSKSDSKKLSRLKKLYMNDTKKLTIDQIRSVTDERTYRKTQGSTVQMIFANFTNT 627

		                +     K +S ++K Y+N+    T + I+  T+             +I +    T

		Sbjct: 752 SICVFVEDIYPKFISYMEK-YINNINIKTREFIQRCTN-----INDNEKSILINSYTFKT 805

		

		Query: 628 TSSKELDEFNKTTVFSE 644

		              K LD  +    F+ 

		Sbjct: 806 IDFKFLDIQSIKNFFNS 822

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 60.1 bits (145), Expect = 2e-11

		 Identities = 32/220 (14%), Positives = 72/220 (32%), Gaps = 19/220 (8%)

		

		Query: 12   KSQQAEEEARLKAEEEARLKAEEEARLKAEEEAR---LKAEEEARLKAEEEARLKAEEEA 68

		              Q          EE AR+             +      AE   +     E   +   E 

		Sbjct: 1002 NIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATET 1061

		

		Query: 69   RLKAEEEAR-LKAEEEARLKAEEEARLKAEEE--ARLKAEEEARLKAEEEARLKAEEEAR 125

		              +  E A+  K+  +A  +  E A+  +E +     + +E A ++ EE+A+++ E+   

		Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKT-- 1119

		

		Query: 126  LKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAE 185

		               +E  ++ ++   + +  E  + +AE           +    +       E+   +  

		Sbjct: 1120 ---QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETS 1176

		

		Query: 186  EEARRAEESAKKVKQGGRLFGRKKDKIEKNNANSNSEKKQ 225

		                +    +  V  G        + + +N  N+     Q

		Sbjct: 1177 SNVEQPVTESTTVNTG--------NSVVENPENTTPATTQ 1208

		

		

		

		 Score = 58.5 bits (141), Expect = 5e-11

		 Identities = 43/287 (14%), Positives = 97/287 (33%), Gaps = 20/287 (6%)

		

		Query: 11   KKSQQAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARL 70

		            + ++   E ++ +++     K E++A  +   + R  A+E    K+  +A  +  E A+ 

		Sbjct: 1035 ETTETVAENSKQESKTVE--KNEQDAT-ETTAQNREVAKEA---KSNVKANTQTNEVAQS 1088

		

		Query: 71   KAEEE--ARLKAEEEARLKAEEEARLKAE---EEARLKAEEEARLKAEEEARLKAEEEAR 125

		             +E +     + +E A ++ EE+A+++ E   E  ++ ++   + +  E  + +AE    

		Sbjct: 1089 GSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARE 1148

		

		Query: 126  LKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAE 185

		                   +    +       E+   +          E   +          E       +

		Sbjct: 1149 NDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQ 1208

		

		Query: 186  EEARRAEESAKKVKQGGRLFGRKKDKIEKNNANSNSEKKQGLFARLKS--GLSKTRENLA 243

		                   ES+ K K   R   R      +    S++++       L S    +   +  A

		Sbjct: 1209 PTVN--SESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARA 1266

		

		Query: 244  SGITTLLIGEKKIDDELLEDLETQLLMADVGIDATTHIITDLTKRLD 290

		                  L   K +   +     +QL M + G        T + K   

		Sbjct: 1267 KAQFVALNVGKAVSQHI-----SQLEMNNEGQYNVWVSNTSMNKNYS 1308

		

		

		

		 Score = 44.7 bits (105), Expect = 1e-06

		 Identities = 29/169 (17%), Positives = 57/169 (33%), Gaps = 13/169 (7%)

		

		Query: 35   EARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARL 94

		               L   E  +     +                     EE AR+             +  

		Sbjct: 977  RYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSET 1036

		

		Query: 95   KAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEEEARLKAEE 154

		                    K E +   K E++A  +   + R  A+E    K+  +A  +  E A+  +E 

		Sbjct: 1037 TETVAENSKQESKTVEKNEQDAT-ETTAQNREVAKEA---KSNVKANTQTNEVAQSGSE- 1091

		

		Query: 155  EARLKAEEEARLKAEEEARLKAEEEARLKAE---EEARRAEESAKKVKQ 200

		                  +E    + +E A ++ EE+A+++ E   E  +   + + K +Q

		Sbjct: 1092 -----TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQ 1135

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 37.6 bits (87), Expect = 6e-06

		 Identities = 10/50 (20%), Positives = 22/50 (44%)

		

		Query: 80  IMPELQGQGYGHYLLDAIVKEVMGQGASDVFLEVRESNLAALKLYNGYGF 129

		           +  + + +G G  LL   ++         + LE ++ N++A   Y  + F

		Sbjct: 97  VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score =  210 bits (535), Expect = 1e-62

		 Identities = 122/462 (26%), Positives = 207/462 (44%), Gaps = 49/462 (10%)

		

		Query: 9   KRRTFAIISHPDAGKTTLTEKLLLFGGAIQMAGTV-KGRKASRHATSDWMELEKQRGISV 67

		           K     +++H DAGKTTLTE LL   GAI   G+V KG        +D   LE+QRGI++

		Sbjct: 2   KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKG-----TTRTDNTLLERQRGITI 56

		

		Query: 68  TTSVMQFPYRERIINLLDTPGHEDFSEDTYRTLTAVDSALMVVDAAKGVEARTLKLWEVC 127

		            T +  F +    +N++DTPGH DF  + YR+L+ +D A++++ A  GV+A+T  L+   

		Sbjct: 57  QTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116

		

		Query: 128 QLRKTAAMTFVNKLDREARDPVEVLDDIETSLGIFCAPITWPIGMGKNFKGIYHLYEDKV 187

		           +      + F+NK+D+   D   V  DI+  L                          KV

		Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ------------------KV 158

		

		Query: 188 YLYSAGKNQQVQDAEVIVGLDNPVLDDKL--GMMASELRDELELVRGASHEFDNAAYLAG 245

		            LY         ++E    +     +D L    M+ +  + LEL +  S  F N      

		Sbjct: 159 ELYPNMCVTNFTESEQWDTVIE--GNDDLLEKYMSGKSLEALELEQEESIRFHN-----C 211

		

		Query: 246 ELTPVFFGSAINNFGIRELLNYFADYAPAPQVRKTHERTVAPTEDKLSGFVFKIQANMDP 305

		            L PV+ GSA NN GI  L+    +   +     TH       + +L G VFKI+     

		Sbjct: 212 SLFPVYHGSAKNNIGIDNLIEVITNKFYSS----THR-----GQSELCGKVFKIE--YSE 260

		

		Query: 306 AHRDRIAFMRVCAGKYTKGMKLKHVRTGKTVQIANAMTFMAGDRSQAEEAYPGDILGLHN 365

		             R R+A++R+ +G       ++     K ++I    T + G+  + ++AY G+I+ L N

		Sbjct: 261 K-RQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKIDKAYSGEIVILQN 318

		

		Query: 366 HGTIQIGDAFTQGEDLKFVGIPNFA-PELFRLVRLRDPLKSKALQKGLIQLSEEGAT-QV 423

		              +++       + L          P L   V    P + + L   L+++S+     + 

		Sbjct: 319 EF-LKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRY 377

		

		Query: 424 FRPLNSNDLILGAVGVLQFDVVAHRLKSEYNVECVYSNISIA 465

		           +    ++++IL  +G +Q +V    L+ +Y+VE      ++ 

		Sbjct: 378 YVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVI 419

		

		

		>PF04183#IucA / IucC family

		          Length = 580

		

		 Score = 26.8 bits (59), Expect = 0.030

		 Identities = 12/54 (22%), Positives = 22/54 (40%), Gaps = 3/54 (5%)

		

		Query: 66  FQFALLNQANLSGAQLSQAVLTRKRRYLGRYFAHPMMQNRRAKRDDYKPSAVRV 119

		           F   L+ +  +   +  Q +      Y+ +   HP M  R A    ++P  +RV

		Sbjct: 491 FISPLMVRLGVPERRFYQLLAAVLSDYMKK---HPQMSERFALFSLFRPQIIRV 541

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 37.4 bits (86), Expect = 2e-04

		 Identities = 32/151 (21%), Positives = 53/151 (35%), Gaps = 24/151 (15%)

		

		Query: 340  SLFYLMRKNNALLALHH--------------GQALNSANAAVTADPYDETAIVPSSPQTQ 385

		            +  Y +R  N    L++                  N+  A V + P +   I  +     

		Sbjct: 966  AWKYKLRNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEI--ARVDEA 1023

		

		Query: 386  TQTQTAEKVIAKITTETTKINQQSVSKKKEPEKAQALKINQNKTQVKPAAKLSHVKVAAP 445

		                 A    ++ TTET   N +  SK  E  +  A +      +V   AK +       

		Sbjct: 1024 PVPPPAPATPSE-TTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSN------- 1075

		

		Query: 446  VEKTSSVEKVAVKAQQIKQQQTNVTKKTPKV 476

		            V+  +   +VA    + K+ QT  TK+T  V

		Sbjct: 1076 VKANTQTNEVAQSGSETKETQTTETKETATV 1106

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 33.3 bits (76), Expect = 0.001

		 Identities = 16/146 (10%), Positives = 48/146 (32%), Gaps = 5/146 (3%)

		

		Query: 118 EEQRVLQSEVQAEQTPNEAQQTVQLERRTVGREQQAQTAEVRRSEAQEQ----QQQVVSR 173

		           EE+ +  + +  EQ      Q  Q E     +  +  T   R +  +      + ++   

		Sbjct: 181 EEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDF 240

		

		Query: 174 RTAADAGKVAESQALREQQGFIDNIRAQRRQADSLDDQKLQARRVEGGVQEHAAELRVAS 233

		            +      +A+   L ++  +++ +   R     L+  + +    +   Q      +   

		Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI 300

		

		Query: 234 RQQSAE-IDQLAAVRQRNTQVADQQA 258

		             +  +  D +  +     +  ++Q 

		Sbjct: 301 LDKLRQTTDNIGLLTLELAKNEERQQ 326

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 40.2 bits (94), Expect = 1e-05

		 Identities = 75/419 (17%), Positives = 160/419 (38%), Gaps = 44/419 (10%)

		

		Query: 12  VMIPELMHYFNVGATSVGTFAGFYFYAYTPMQLIVGPLFDRFRAHQLLTLAVIACALGTI 71

		           V +P++ + FN    S       +   ++    + G L D+    +LL   +I    G++

		Sbjct: 35  VSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSV 94

		

		Query: 72  LTGIAPTDHITIAYAGRFLQGFGSAFAFVGILKLGATILPHNRLALIAGLVTCLGFVGAM 131

		           +  +  +   ++    RF+QG G+A     ++ + A  +P        GL+  +  +G  

		Sbjct: 95  IGFVGHS-FFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEG 153

		

		Query: 132 AGQNSLAALVTHFNWQ-----PVLITIGLF-------------------GFILAPIFF-F 166

		            G      +  + +W      P++  I +                    G IL  +   F

		Sbjct: 154 VGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVF 213

		

		Query: 167 FVRNPHSTSTNHTSQQMSSKDIFQGFLLTIKQPYL---------WLVGLAGGALFMPNSV 217

		           F+    S S +     + S  IF   +  +  P++         +++G+  G +    +V

		Sbjct: 214 FMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIF-GTV 272

		

		Query: 218 FASLWGIPFLTQT-HHLSTAHATFATSLIFLGW---AIGSPLQGWLSDRLRTARLQLIFV 273

		              +  +P++ +  H LST  A   + +IF G     I   + G L DR R     L   

		Sbjct: 273 AGFVSMVPYMMKDVHQLST--AEIGSVIIFPGTMSVIIFGYIGGILVDR-RGPLYVLNIG 329

		

		Query: 274 NILIAATIIYLVIAIPGLNYTLLCILLLAFGIFASAEIAVFPLAIEHMPTQYSGTAIAFV 333

		              ++ + +     +   ++ +  I++   G  +  +  +  +    +  Q +G  ++ +

		Sbjct: 330 VTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLL 389

		

		Query: 334 NFLTMLGGLTMQRGIGEILDLEW-DGTLSHGIRVYSSTVYSYALYTLPLILLIAAVCVI 391

		           NF + L   T    +G +L +   D  L       S+ +YS  L     I++I+ +  +

		Sbjct: 390 NFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTL 448

		

		

		>BONTOXILYSIN#Bontoxilysin signature.

		          Length = 1196

		

		 Score = 25.6 bits (56), Expect = 0.024

		 Identities = 7/40 (17%), Positives = 14/40 (35%)

		

		Query: 30  GQWWLTRVKTINGKKEIKKDACENYQAGIKRIGHIKYHYE 69

		            QWW            + K +    ++ +K+I   K+   

		Sbjct: 670 DQWWTEYYSQYFELICMAKQSILAQESLVKQIVQNKFTDL 709

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  103 bits (259), Expect = 7e-29

		 Identities = 56/191 (29%), Positives = 102/191 (53%), Gaps = 2/191 (1%)

		

		Query: 5   LDGKVAIITGAASGLGLSIAEKYARSGANVVIADLNPDQAREVAAGIAKRNKVTAVGILM 64

		           ++GK+A ITGAA G+G ++A   A  GA++   D NP++  +V + +    +  A     

		Sbjct: 6   IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEAR-HAEAFPA 64

		

		Query: 65  DVTSEEQVNEGVQKIANDLGTVDILVSNAGIQTIAPIVEFDYDDWKRLLDIHINGTFLTT 124

		           DV     ++E   +I  ++G +DILV+ AG+     I     ++W+    ++  G F  +

		Sbjct: 65  DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124

		

		Query: 125 KACMQQMIRSGRGGSIIIMGSIHSVEASMNKSAYVTAKHGLLGFTRALAKEGAIHNIRAN 184

		           ++  + M+   R GSI+ +GS  +     + +AY ++K   + FT+ L  E A +NIR N

		Sbjct: 125 RSVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183

		

		Query: 185 LIGPGFVKTPL 195

		           ++ PG  +T +

		Sbjct: 184 IVSPGSTETDM 194

		

		

		>PF03309#Bvg accessory factor

		          Length = 271

		

		 Score = 29.3 bits (66), Expect = 0.016

		 Identities = 15/66 (22%), Positives = 25/66 (37%), Gaps = 4/66 (6%)

		

		Query: 1  MILVLDLGGTKLAAALFDGD----KLFERQQRATCAAADCEPLKQQLSELIAEYHGRFTA 56

		          M+L +D+  T     L  G     K+ ++ +  T      + L   +  LI +   R T 

		Sbjct: 1  MLLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDGLIGDDAERLTG 60

		

		Query: 57 ISIACT 62

		           S   T

		Sbjct: 61 ASGLST 66

		

		

		>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase

		           signature.

		          Length = 572

		

		 Score =  299 bits (768), Expect = 3e-94

		 Identities = 114/453 (25%), Positives = 189/453 (41%), Gaps = 72/453 (15%)

		

		Query: 365 RLLKSL-----QDMKNFQAGDILV-TDMTDPDWEPIMK-RAAAIVTNRGGRTCHAAIIAR 417

		           R+L  L       +       +++  D+T  D   + K       T+ GGRT H+AI++R

		Sbjct: 137 RVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSR 196

		

		Query: 418 ELGVPAVVGCGDATAELVEGQIVTVSCAEG---------DTGYIYEGALGFDVQEINCEA 468

		            L +PAVVG  + T ++  G +V V   EG         +     E    F+ Q+     

		Sbjct: 197 SLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQKQEWAK 256

		

		Query: 469 MPKIP--------VKIMMNVAHPERAFALSRLPHEGVGLARLEFVIGRTIGIHPQALLEY 520

		           +   P        V++  N+  P+    +     EG+GL R EF+            ++ 

		Sbjct: 257 LVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLY-----------MDR 305

		

		Query: 521 DQQPEAVKAEIDERTAAYGSPVDFYVEKIVESIATLAAAFAPKRVIVRLSDFKSNEYANL 580

		           DQ P       +E+  AY                 +      K V++R  D   ++  + 

		Sbjct: 306 DQLPTE-----EEQFEAY---------------KEVVQRMDGKPVVIRTLDIGGDKELSY 345

		

		Query: 581 LGGDVYEPHEENPMIGFRGASRYVSDSFKPCFELECRALLKVREEYGFKNVDVMVPFVRT 640

		           L      P E NP +GFR     +    +  F  + RALL+      + N+ VM P + T

		Sbjct: 346 L----QLPKELNPFLGFRAIRLCLE--KQDIFRTQLRALLRAS---TYGNLKVMFPMIAT 396

		

		Query: 641 LSEGQQVVEL-------LSAYGINKSHDMNLHMMCELPSNVILIDEFLDIFDGVSIGSND 693

		           L E +Q   +       L + G++ S  + + +M E+PS  +  + F    D  SIG+ND

		Sbjct: 397 LEELRQAKAIMQEEKDKLLSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTND 456

		

		Query: 694 LTQLTLGLDRDSGIVAHLFDERNLAVKRLLQQVISRCKARGRYVGICGQGPSDYPELAKW 753

		           L Q T+  DR +  V++L+   + A+ RL+  VI    + G++VG+CG+   D       

		Sbjct: 457 LIQYTMAADRMNERVSYLYQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGD-EVAIPL 515

		

		Query: 754 LLEQGIDSLSLNADTVLSTWLALAKEKVPAASE 786

		           LL  G+D  S++A ++L     L K        

		Sbjct: 516 LLGLGLDEFSMSATSILPARSQLLKLSKEELKP 548

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 29.0 bits (65), Expect = 0.034

		 Identities = 25/183 (13%), Positives = 60/183 (32%), Gaps = 33/183 (18%)

		

		Query: 65  ILGRIGDQHGRKKVLLLSISIMTISTFCIALLPTYSQTGIIAPILFILLRLIQGLAISAE 124

		           +LG + D+ GR+ VLL+S++   +    +A  P          +L+I  R++ G+   A 

		Sbjct: 62  VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW-------VLYI-GRIVAGIT-GAT 112

		

		Query: 125 FTCSTSY-----QIERKSNKKSYLGALVQSTTLIGSLFAALVVSLLSFLLPHDQLVSWGW 179

		              + +Y       + ++    ++ A      + G +   L             +  +  

		Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL-------------MGGFSP 159

		

		Query: 180 RVPFLISGFCGI------YLIKLRSKLPEPDEFNKINEKEKSLKNKKNYISSNKKIIFLS 233

		             PF  +             +   S   E     +      +       ++    ++ + 

		Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVF 219

		

		Query: 234 FFI 236

		           F +

		Sbjct: 220 FIM 222

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score =  118 bits (298), Expect = 6e-32

		 Identities = 84/384 (21%), Positives = 153/384 (39%), Gaps = 23/384 (5%)

		

		Query: 7   QLTAILLITLLGFIGLAIPYPILAPMLLKNEAFSLHTHATRMIWYGALLAAYPIGQFLGS 66

		            L  IL    L  +G+ +  P+L P LL++    L         YG LLA Y + QF  +

		Sbjct: 6   PLIVILSTVALDAVGIGLIMPVL-PGLLRD----LVHSNDVTAHYGILLALYALMQFACA 60

		

		Query: 67  AILGDLSDHWGRRKILILSLLLTTIGYAISAIAVYQHYLGLFLFARLFTGLAEGNVAICR 126

		            +LG LSD +GRR +L++SL    + YAI A A    +L +    R+  G+     A+  

		Sbjct: 61  PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATA---PFLWVLYIGRIVAGITGATGAVAG 117

		

		Query: 127 AAAADLSPKISKYTSFGLINAAGTCGFIIGPILAGVFSDKTIYLGFSYATPFFIALLLSL 186

		           A  AD++    +   FG ++A    G + GP+L G+         FS   PFF A  L+ 

		Sbjct: 118 AYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG------FSPHAPFFAAAALNG 171

		

		Query: 187 FTLIATYFFFTETFNPIKNKAHQAFSLFSLLITAMNNIIFTVRLQHIKWLLFSALLLMFS 246

		              +   F   E+    +    +        +  + +  +   +  +  L+    ++   

		Sbjct: 172 LNFLTGCFLLPESHKGERRPLRR------EALNPLASFRWARGMTVVAALMAVFFIMQLV 225

		

		Query: 247 VDLTYQFAPLFLTAHWQMTSLAIAKTLFVLWVSIIIGEVWLVPLLAKRFNKYKLIFNSTI 306

		             +      +F    +   +  I  +L    +   + +  +   +A R  + + +    I

		Sbjct: 226 GQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMI 285

		

		Query: 307 ALSIFLILMIITTYLALLYAALFLLGLFIALSTTLATILISDAVNPHIQGRILGTFSSLR 366

		           A     IL+   T   + +  + LL         L  + +S  V+   QG++ G+ ++L 

		Sbjct: 286 ADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAM-LSRQVDEERQGQLQGSLAALT 344

		

		Query: 367 VLGDAIGAITGGLCAIFYPEAPLW 390

		            L   +G +     AI+      W

		Sbjct: 345 SLTSIVGPLLFT--AIYAASITTW 366

		

		

		

		 Score = 29.4 bits (66), Expect = 0.030

		 Identities = 26/116 (22%), Positives = 50/116 (43%), Gaps = 1/116 (0%)

		

		Query: 291 LAKRFNKYKLIFNSTIALSIFLILMIITTYLALLYAALFLLGLFIALSTTLATILISDAV 350

		           L+ RF +  ++  S    ++   +M    +L +LY    + G+  A +  +A   I+D  

		Sbjct: 66  LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYIADIT 124

		

		Query: 351 NPHIQGRILGTFSSLRVLGDAIGAITGGLCAIFYPEAPLWLAVSMLIISLILLLVT 406

		           +   + R  G  S+    G   G + GGL   F P AP + A ++  ++ +     

		Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFL 180

		

		

		>FLGFLIJ#Flagellar FliJ protein signature.

		          Length = 147

		

		 Score = 41.3 bits (96), Expect = 2e-07

		 Identities = 35/142 (24%), Positives = 68/142 (47%), Gaps = 2/142 (1%)

		

		Query: 1   MKRSQRLVNIIKIAEYQERKLAKQLAASRNTLKQYQEQLAMLDLYLNDYLKKLSAIKKNN 60

		           M     L  +  +AE +    A+ L   R   +Q +EQL ML  Y N+Y   L++     

		Sbjct: 1   MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60

		

		Query: 61  QEVTVNELTIYHDFIQTIEQGIQRQQHFIADASTVIQRHEQEWRKARAKVESFKHLQQKF 120

		             +T N    Y  FIQT+E+ I + +  +   +  +      WR+ + ++++++ LQ++ 

		Sbjct: 61  --ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQ 118

		

		Query: 121 KNAEDRELDRQEQRMIDDYVNR 142

		             A     +R +Q+ +D++  R

		Sbjct: 119 STAALLAENRLDQKKMDEFAQR 140

		

		

		>FLGHOOKFLIK#Flagellar hook-length control protein signature.

		          Length = 375

		

		 Score = 46.4 bits (109), Expect = 2e-07

		 Identities = 44/167 (26%), Positives = 74/167 (44%), Gaps = 15/167 (8%)

		

		Query: 344 PSVAQHFDQPLPLVDEAELAPALG---------QRLQIMLNRQLNNATIALDPPELGPLM 394

		           P +  H  QPLP V    L+  LG         Q + +   +   +A + L P +LG + 

		Sbjct: 213 PLITPHQTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQ 272

		

		Query: 395 IKLHVDASQKTHLTFTTHSDVVREMIEQQLPRLKDMFDSQGLALGDANVAGQGAFSQGQH 454

		           I L VD +Q      + H   VR  +E  LP L+      G+ LG +N++G+    Q Q 

		Sbjct: 273 ISLKVDDNQAQIQMVSPHQH-VRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQA 331

		

		Query: 455 FNEEKEHNKNNMSKAQESVDILADEHKVEPA--EGQYIRDLGVDLFA 499

		            +++++  +    +     D   D+    P   +G+   + GVD+FA

		Sbjct: 332 ASQQQQSQRTANHEPLAGED---DDTLPVPVSLQGRVTGNSGVDIFA 375

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 45.6 bits (108), Expect = 2e-07

		 Identities = 58/361 (16%), Positives = 126/361 (34%), Gaps = 32/361 (8%)

		

		Query: 40  VITKELMHAFTINATGVGLLSSFYYYSYAAMQIPAGLAFDRMNARILITVSLTICAIGIL 99

		            + ++L+H+  +     G+L + Y     A     G   DR   R ++ VSL   A+   

		Sbjct: 30  GLLRDLVHSNDV-TAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYA 88

		

		Query: 100 LFSLTDSFTLASLGRFFTGFGSAFAFIAMLFIA---AQWFPTRYFGLIAGIGQFLASIGA 156

		           + +      +  +GR   G   A   +A  +IA         R+FG ++         G 

		Sbjct: 89  IMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSAC----FGFGM 144

		

		Query: 157 LAGQGPLAAIVSDLGWREALQGLGFIGITLAIIILLILKDKRHHHTDNQPITKKPKTTPN 216

		           +AG   L  ++              +     +    +L +           + K +  P 

		Sbjct: 145 VAGPV-LGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPE-----------SHKGERRPL 192

		

		Query: 217 NRLSIKQQLTILFKHPETFKIALY--SFAAWAPITIFASLWGVPFLRAHYQLTINDAANL 274

		            R ++    +  +    T   AL    F       + A+LW V F    +     DA  +

		Sbjct: 193 RREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALW-VIFGEDRFHW---DATTI 248

		

		Query: 275 SSTIWLGIALGSPLIGYWSDKIRQR---KPLLLLSATLGIIASLIVLYSPSLPVTLLYVL 331

		             ++     L S      +  +  R   +  L+L         +++ ++    +    ++

		Sbjct: 249 GISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMV 308

		

		Query: 332 MF-FFGVGA-AGQSLSFAYIKDYQQDNILGTAIGFNNMAVVISGALFQPLVGFIMSQLWD 389

		           +    G+G  A Q++    + + +Q  + G+     ++  ++   LF  +    ++  W+

		Sbjct: 309 LLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITT-WN 367

		

		Query: 390 G 390

		           G

		Sbjct: 368 G 368

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score = 39.8 bits (93), Expect = 4e-05

		 Identities = 36/143 (25%), Positives = 63/143 (44%), Gaps = 32/143 (22%)

		

		Query: 1   MKHIHIALLGNPNSGKTTLFNQL---TGSKQKVG---------NWA------GVTVEKKT 42

		           MK I+I +L + ++GKTTL   L   +G+  ++G         +        G+T++   

		Sbjct: 1   MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGI 60

		

		Query: 43  GSFAYQHHDIQLTDLPG--TYSLNVASAQSSLDERIACEYLLQEKVDLVINIVDAANLER 100

		            SF +++  + + D PG   +   V  + S LD  I           L+I+  D    + 

		Sbjct: 61  TSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAI-----------LLISAKDGVQAQT 109

		

		Query: 101 NLYLTSQLLEMRIPCIIALNMLD 123

		            + L   L +M IP I  +N +D

		Sbjct: 110 RI-LFHALRKMGIPTIFFINKID 131

		

		

		>PF05043#Transcriptional activator

		          Length = 493

		

		 Score = 28.8 bits (64), Expect = 0.007

		 Identities = 18/121 (14%), Positives = 36/121 (29%), Gaps = 17/121 (14%)

		

		Query: 33  AKRLRGKHKPVYTPHVDTGDYIIVVNADKVAVTGNKAKDK-LYHRHTGFPGGIKSLPFDE 91

		             R+  +   V             V+   V + GN+   +  + ++          PF+ 

		Sbjct: 117 LYRIISQINKVIKRQFQFE-----VSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFEN 171

		

		Query: 92  AKAKNPQRVIELAVKGM-LPRGPLGRAMF---------RKLKVYAGAEHDHAAQQPQLLE 141

		             ++   +++EL  K    P       M          R    +   E D  +   Q L+

		Sbjct: 172 FSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHF-MEVDKDSFNDQSLD 230

		

		Query: 142 I 142

		            

		Sbjct: 231 F 231

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score = 72.1 bits (177), Expect = 2e-16

		 Identities = 45/220 (20%), Positives = 83/220 (37%), Gaps = 32/220 (14%)

		

		Query: 6   TVFVTGGTGSFGKMCIAMLLKLWKPRKIIV------YSRDELKQFDMQQEFNQECMRYFI 59

		              VTG  G  G      LL+     +++       Y    LKQ    +   Q   ++  

		Sbjct: 2   KYLVTGAAGFIGFHVSKRLLE--AGHQVVGIDNLNDYYDVSLKQ-ARLELLAQPGFQFHK 58

		

		Query: 60  GDVRDGDRLAR--AMVGVDYVIHAAAMKQVPASEYNPMECIKTNIDGAQNVIKAAIDNKV 117

		            D+ D + +    A    + V  +     V  S  NP     +N+ G  N+++    NK+

		Sbjct: 59  IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118

		

		Query: 118 KKVIALST---------------DKAANPINLYGATKLASDKLFVAANNMVGDGPTRFAV 162

		           + ++  S+               D   +P++LY ATK A++ +    +++ G        

		Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG---LPATG 175

		

		Query: 163 VRYGNVVGSRGS---VVPFFKKLIEQGVTELPITHEKMTR 199

		           +R+  V G  G     +  F K + +G +     + KM R

		Sbjct: 176 LRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKR 215

		

		

		>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature.

		          Length = 591

		

		 Score = 27.4 bits (60), Expect = 0.027

		 Identities = 13/42 (30%), Positives = 18/42 (42%), Gaps = 3/42 (7%)

		

		Query: 96  TTEIVGKNMQMLGGGER---VQTAKPPPPPPSSLGQQAFKAK 134

		           T     + +   G G R   V    PPPPPP  +G  + + K

		Sbjct: 342 TQLCAARTLAYEGDGYRRAPVNNMMPPPPPPPMMGGNSSRPK 383

		

		

		>ENTEROTOXINA#Heat-labile enterotoxin A chain signature.

		          Length = 258

		

		 Score = 33.4 bits (76), Expect = 0.002

		 Identities = 36/132 (27%), Positives = 55/132 (41%), Gaps = 17/132 (12%)

		

		Query: 49  IFCFFIIVIINASVIFASPGPLPPRYFYRADTRTPMQIFGSAHIVGAGFLSWGIARGVAP 108

		            F FFI++        ASP        YRAD+R P +I  S  ++  G  +    RG   

		Sbjct: 5   TFIFFILL--------ASPLYANGDRLYRADSRPPDEIKRSGGLMPRG-HNEYFDRGTQM 55

		

		Query: 109 DYDVVSYAAGITVAPNDNPEDLTAGWVSASGDLYGVEHFLDNEFLGRGRGHPDVWVYQIA 168

		           + ++  +A G T       +D   G+VS S  L    H      L    G+   ++Y IA

		Sbjct: 56  NINLYDHARG-TQTGFVRYDD---GYVSTSLSLRSA-HLAGQSILS---GYSTYYIYVIA 107

		

		Query: 169 PTERAYSVNWML 180

		                ++VN +L

		Sbjct: 108 TAPNMFNVNDVL 119

		

		

		>PF05043#Transcriptional activator

		          Length = 493

		

		 Score = 26.4 bits (58), Expect = 0.004

		 Identities = 9/24 (37%), Positives = 17/24 (70%)

		

		Query: 21  GVKVEDICRQYGIAKSSYYKLRSK 44

		           G + E IC+++ I+ SS Y++ S+

		Sbjct: 100 GCQAESICKEFYISSSSLYRIISQ 123

		

		

		>BORPETOXINA#Bordetella pertussis toxin A subunit signature.

		          Length = 269

		

		 Score = 34.0 bits (77), Expect = 0.002

		 Identities = 49/226 (21%), Positives = 85/226 (37%), Gaps = 36/226 (15%)

		

		Query: 52  FFIIVIINASVIFASPGPLPPRYFYRADTRSPDQIFGNQQEIGSGFMTWAQTRDVSPNYN 111

		           +  I+ + A V   +    PP   YR D+R P+ +F N      GF  W        N N

		Sbjct: 18  WLAILAVTAPVTSPAWADDPPATVYRYDSRPPEDVFQN------GFTAWGN------NDN 65

		

		Query: 112 VIRYTAGDTVSPGPYSARTAGWVSVAGSLEGVMRFLNYEVLQRETETNPA--------YW 163

		           V+ +  G +   G   +  + +VS + S      +L +  +Q   E   A         +

		Sbjct: 66  VLDHLTGRSCQVG---SSNSAFVSTSSSRRYTEVYLEHR-MQEAVEAERAGRGTGHFIGY 121

		

		Query: 164 VYRIESTSRAYSVNWMLDDYINSPSTNTRDHEIAMSLLSRYQEEEEWMVRDGIRPEEIVD 223

		           +Y + + +  Y       +Y+++   N     I    L+ YQ   E++    I PE I  

		Sbjct: 122 IYEVRADNNFYGAASSYFEYVDTYGDNA--GRILAGALATYQ--SEYLAHRRIPPENI-- 175

		

		Query: 224 AAEYEVGFIEYNPTGRTITNPHFVHTELPSQQIE---NPALTERAL 266

		                V  + +N      T   + +    SQQ     NP  + R++

		Sbjct: 176 ---RRVTRVYHNGITGETTTTEYSNARYVSQQTRANPNPYTSRRSV 218

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 27.9 bits (62), Expect = 0.043

		 Identities = 10/43 (23%), Positives = 19/43 (44%), Gaps = 1/43 (2%)

		

		Query: 4   RHLNEKDRFYIEQRLSE-GDSLRSIARALGFSPSTISREIKRH 45

		           R L E +   I   L+    +    A  LG + +T+ ++I+  

		Sbjct: 431 RVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473

		

		

		>ARGREPRESSOR#Bacterial arginine repressor signature.

		          Length = 149

		

		 Score =  117 bits (295), Expect = 9e-37

		 Identities = 36/141 (25%), Positives = 71/141 (50%), Gaps = 5/141 (3%)

		

		Query: 11  VQQLLSDESMSSQEEICRSLAAQNFTVSQSKVSRLLRQCGAVKVQKD-GRLVYGLSKELS 69

		           ++++++   + +Q+E+   L    + V+Q+ VSR +++   VKV  + G   Y L  +  

		Sbjct: 10  IREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQR 69

		

		Query: 70  PPASDS---ALAHLVLSIEHNEVMVVLHTSPGAAQLVARLLDFHPKHSDILGTLAGDDAI 126

		                    +L    + I+    ++VL T PG AQ +  L+D      +I+GT+ GDD I

		Sbjct: 70  FNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWE-EIMGTICGDDTI 128

		

		Query: 127 FVSPRSIKNIEKLYLEIRQLL 147

		            +  R+  + + +  +I +LL

		Sbjct: 129 LIICRTHDDTKVVQKKILELL 149

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score =  537 bits (1384), Expect = 0.0

		 Identities = 281/347 (80%), Positives = 317/347 (91%)

		

		Query: 1   MLKKLRGFFSSDLSIDLGTANTLIYARGQGIVLNEPSVVAIRQDGGHGQKSVAAVGIEAK 60

		           MLKK RG FS+DLSIDLGTANTLIY +GQGIVLNEPSVVAIRQD     KSVAAVG +AK

		Sbjct: 1   MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK 60

		

		Query: 61  RMLGRTPGNMTAIRPMKDGVIADFYVTERMLKHFIQKVHAEKWIKPSPRVLVCVPCGSTQ 120

		           +MLGRTPGN+ AIRPMKDGVIADF+VTE+ML+HFI++VH+  +++PSPRVLVCVP G+TQ

		Sbjct: 61  QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ 120

		

		Query: 121 VERRAIRESALGAGAREVYLIEEPMSAAVGAGLPVEEAAGSMVVDIGGGTTEIAIISLSG 180

		           VERRAIRESA GAGAREV+LIEEPM+AA+GAGLPV EA GSMVVDIGGGTTE+A+ISL+G

		Sbjct: 121 VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG 180

		

		Query: 181 IVYSASVRIGGDRFDEAIVSYVRRNYGCLIGEATAERIKHEIGSAYPGNEVREMEVRGRN 240

		           +VYS+SVRIGGDRFDEAI++YVRRNYG LIGEATAERIKHEIGSAYPG+EVRE+EVRGRN

		Sbjct: 181 VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN 240

		

		Query: 241 LAEGVPRSFTLNSNEILEALQEPLMGIVSAVKAALEQAPPELAADIAEKGMVLTGGGALL 300

		           LAEGVPR FTLNSNEILEALQEPL GIVSAV  ALEQ PPELA+DI+E+GMVLTGGGALL

		Sbjct: 241 LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL 300

		

		Query: 301 RDLDRLLMEETSLPVLVAEDPLTCVARGGGRALELADERGFDFLATE 347

		           R+LDRLLMEET +PV+VAEDPLTCVARGGG+ALE+ D  G D  + E

		Sbjct: 301 RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347

		

		

		>FbpA_PF05833#Fibronectin-binding protein

		          Length = 577

		

		 Score = 28.7 bits (64), Expect = 0.036

		 Identities = 19/118 (16%), Positives = 40/118 (33%), Gaps = 14/118 (11%)

		

		Query: 29  DRYTEQTKMIRITLSSVLYPFEYAAAAPYQLSQWLKHSVSERYQLFIENKKLNEEVVRLQ 88

		           + Y+E    ++ITL     P +   +  Y+    LK S     +      +  EE+  L 

		Sbjct: 360 NYYSENYDTVKITLDENKTPSQNVQSY-YKKYNKLKKSEEAANEQL---LQNEEELNYLY 415

		

		Query: 89  VMLQQLLV---------IKTENQQLQALLNASHKLSPQRYRLAKVLQVKTSAYKQMIV 137

		            +L  +           IK E  +    +        ++ + +K +   +     + V

		Sbjct: 416 SVLTNINNADNYDEIEEIKKELIE-TGYIKFKKIYKSKKSKTSKPMHFISKDGIDIYV 472

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 38.3 bits (89), Expect = 3e-05

		 Identities = 16/111 (14%), Positives = 42/111 (37%), Gaps = 11/111 (9%)

		

		Query: 180 TVLLVDDSRVAKRQIANILDQLKVQYITASDGIEAFEMLTKMVEGTDNINSKLLMMLSDI 239

		           T+L+ DD    +  +   L +        S+    +  +               ++++D+

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGD---------LVVTDV 55

		

		Query: 240 EMPNMDGYTLTSKCREHPKLKDLYIVLNTSISGEFNQQMAKRVKADQFLAK 290

		            MP+ + + L  + ++     DL +++ ++ +       A    A  +L K

		Sbjct: 56  VMPDENAFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK 104

		

		

		>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature.

		          Length = 293

		

		 Score = 94.8 bits (235), Expect = 7e-25

		 Identities = 64/246 (26%), Positives = 116/246 (47%), Gaps = 5/246 (2%)

		

		Query: 48  CRLTHEIPHYGQAMFEMRTGRLQS--FVLDTHVGPSRKEPVTLTTGSPGWRLPEALILND 105

		           C+L H IP +G A+F  R  +  +  F L           V+L +  P WR  E      

		Sbjct: 46  CQLVHPIPSFGDAVFSSRASKKINLDFELKMRRPMGETRNVSLISMPPPWRPGEHADRIT 105

		

		Query: 106 HAKMSQGYAPFRFGTMTVRRMLNSLAQGYAPTLAYQSWLGNRQQVQVSISPANFSQPYTQ 165

		           + K  + +  +  G  T   +L+ L +G  PT +YQ W    Q+++V++S   F   Y  

		Sbjct: 106 NLKFFKQFDGY-VGGQTAWGILSELEKGRYPTFSYQDWQSRDQRIEVALSSVLFQSKYNA 164

		

		Query: 166 YLACSKKILPFTFVDIEHTVIYFGVNDRRILKDQRYKLERIQEYFKVMKPKIRRIVIKGY 225

		           +  C   +L ++F DI  T++++     ++ K  + +L +I +Y +     I  +++  Y

		Sbjct: 165 FSDCIANLLKYSFEDIAFTILHYERQGDQLTKASKKRLAQIADYVR-HNQDIDLVLVATY 223

		

		Query: 226 ADYAGNYLYNKYLSIDRAKALRKFIVEDMKFDAKKLVVRAYGVGQAVANNSTRSGRALNR 285

		            D       ++ LS  RA++LR +  E +     ++ V+ YG  + +A+N T  G+  NR

		Sbjct: 224 TDSTDGKSESQSLSERRAESLRTYF-ESLGLPEDRIQVQGYGKRRPIADNGTPIGKDKNR 282

		

		Query: 286 RATIDI 291

		           R  I +

		Sbjct: 283 RVVISL 288

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 72.8 bits (178), Expect = 4e-15

		 Identities = 60/301 (19%), Positives = 93/301 (30%), Gaps = 33/301 (10%)

		

		Query: 405  NP--AGHDRDILTTQIDNIRHSTWGVKAAVANNATISLGDAAQELKTGGTAGASELVDTE 462

		            NP     ++ + TT I    +    V +  +NN  I+      E      A A+    TE

		Sbjct: 982  NPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIA---RVDEAPVPPPAPATPSETTE 1038

		

		Query: 463  LVAPEGDSQEAE----SPEAESSEGDSSEGDSPEGETPEAETPEAETPEAETPEAETPEA 518

		             VA     +         +A  +   + E         +A T   E  ++ +   ET   

		Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098

		

		Query: 519  ETPEAETPEAETPEGETPEAETPEGETPEGETPEAETPEAETPEAETPEAETPEAETPEA 578

		            ET E  T E E       E      +     +P+ E  E   P+AE      P     E 

		Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158

		

		Query: 579  ETPEGETPETETP-----------------------ETETPETETPEAETSEIVEEVEEE 615

		            ++    T +TE P                         E PE  TP      +  E   +

		Sbjct: 1159 QSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNK 1218

		

		Query: 616  GAVNVNVSVRGGGEHQDVQSVSLEEGD-EATLTMGDSETEVALDDIRLEENSEEESVGAD 674

		                   SVR    + +  + S  +    A   +  + T   L D R +      +VG  

		Sbjct: 1219 PKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKA 1278

		

		Query: 675  V 675

		            V

		Sbjct: 1279 V 1279

		

		

		

		 Score = 31.2 bits (70), Expect = 0.017

		 Identities = 34/256 (13%), Positives = 70/256 (27%), Gaps = 10/256 (3%)

		

		Query: 82   IAQAKRVKAQPKVQSPVKAKPEVTTVIVPSKPQKVLIEKKVSYIPTDKPRQIDNELKKQL 141

		            IA+       P   +      E        + + V   ++ +   T + R++  E K  +

		Sbjct: 1017 IARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNV 1076

		

		Query: 142  GYITQQMSA--LTHSVEEVQEEMLSVARDVQQTSNGVLQLEEYQQQLQHAEQERIARQEA 199

		               TQ           +E Q         V++     ++ E+ Q+  +   Q    ++++

		Sbjct: 1077 KANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQS 1136

		

		Query: 200  AESMQSKQNEIAEIPVELGVHNVVTPAEPSLDQSPAASESRITHYLQGTIFDWLLLGFTL 259

		                   +      P              +  + PA   S              +     

		Sbjct: 1137 ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTE--STTVNTGNS 1194

		

		Query: 260  VVLIPLVMLKRYLRDRKLTEKTAPLSKAKKASNVKISSERKEPVVQSVLKKETAAVAMSS 319

		            VV  P           + T  +   +K K      + S        +    + + VA   

		Sbjct: 1195 VVENPENTTP---ATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA--- 1248

		

		Query: 320  MVDDVSTKRKSATHPA 335

		            + D  ST   +    A

		Sbjct: 1249 LCDLTSTNTNAVLSDA 1264

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  135 bits (341), Expect = 5e-41

		 Identities = 81/248 (32%), Positives = 119/248 (47%), Gaps = 10/248 (4%)

		

		Query: 4   KLALITGASRGIGRAVLNELGRQGLTVVGTATTEAGAENITGFINEQGYKGCGLALNVTE 63

		           K+A ITGA++GIG AV   L  QG  +          E +   +  +         +V +

		Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68

		

		Query: 64  PEQIIAAVDKITKEFGPVQVLVNNAGITRDNLMLRMKDEDWNAVIETNLSAVFRVTKACL 123

		              I     +I +E GP+ +LVN AG+ R  L+  + DE+W A    N + VF  +++  

		Sbjct: 69  SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128

		

		Query: 124 KGMMKVRWGRIINIGSVVGNMGNPGQANYCAAKAGLVGVTKSMAHEFASRNITVNVIAPG 183

		           K MM  R G I+ +GS    +     A Y ++KA  V  TK +  E A  NI  N+++PG

		Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188

		

		Query: 184 FIQTDM-----TDALAEEQRVA-LLEH----IPAKRLGQPEDIAHMAAFLSSEAASYLTG 233

		             +TDM      D    EQ +   LE     IP K+L +P DIA    FL S  A ++T 

		Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248

		

		Query: 234 QTLHINGG 241

		             L ++GG

		Sbjct: 249 HNLCVDGG 256

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 26.0 bits (57), Expect = 0.017

		 Identities = 11/42 (26%), Positives = 19/42 (45%), Gaps = 2/42 (4%)

		

		Query: 34  GADSLDTVELVMALEEEFETEIPDEDAEKIATVQDAMNYVKQ 75

		           GA++LDT + + A   E +   P     K+    D   +V+ 

		Sbjct: 296 GANALDTAKAIKAKLAELQPFFP--QGMKVLYPYDTTPFVQL 335

		

		

		>BCTERIALGSPD#Bacterial general secretion pathway protein D

		           signature.

		          Length = 660

		

		 Score = 26.8 bits (59), Expect = 0.044

		 Identities = 20/98 (20%), Positives = 29/98 (29%), Gaps = 21/98 (21%)

		

		Query: 18  TCCLLLSFLATSSANYAATANTNTNTRQSFTQAFNNSKALAVSK-LGQTF--------EI 68

		           T  +  + L   +A    +A+      Q F           VSK L +T          I

		Sbjct: 13  TLLIFAALLFRPAAAEEFSASFKGTDIQEFIN--------TVSKNLNKTVIIDPSVRGTI 64

		

		Query: 69  KV----PANPTTGFSWFLKSYDHDLLDVVNQRYNAPKT 102

		            V      N    + +FL   D     V+N      K 

		Sbjct: 65  TVRSYDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKV 102

		

		

		>UREASE#Urea amidohydrolase (urease) protein signature.

		          Length = 570

		

		 Score = 27.4 bits (61), Expect = 0.003

		 Identities = 5/28 (17%), Positives = 11/28 (39%), Gaps = 3/28 (10%)

		

		Query: 6   PVRACAVPRYDVTKKDLPLSCPMPQMEI 33

		            V+     R  + K  +  +   P +E+

		Sbjct: 515 AVQNT---RGGIGKASMIHNSLTPHIEV 539

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score =  121 bits (304), Expect = 4e-34

		 Identities = 88/354 (24%), Positives = 147/354 (41%), Gaps = 73/354 (20%)

		

		Query: 2   IIVTGGAGFIGSNLIKQLNEQGHREILVVDDLSDGKKFVNLADCDILDYLDKN-QFIE-K 59

		            +VTG AGFIG ++ K+L E GH +++ +D+L+D    V+L    +        QF +  

		Sbjct: 3   YLVTGAAGFIGFHVSKRLLEAGH-QVVGIDNLNDYYD-VSLKQARLELLAQPGFQFHKID 60

		

		Query: 60  IKNNDDFSDYVK-----VVFHQGACSKTTEWDGRYMMDNNYEYSK-------QLLHYCMA 107

		           + + +  +D         VF             RY ++N + Y+         +L  C  

		Sbjct: 61  LADREGMTDLFASGHFERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNILEGCRH 115

		

		Query: 108 RGI-AFIYASSAAVYGGSET--FKESRQFEKPLNVYGYSKWQFDQYVRQCALSAHS---- 160

		             I   +YASS++VYG +    F      + P+++Y  +K       +   L AH+    

		Sbjct: 116 NKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATK-------KANELMAHTYSHL 168

		

		Query: 161 ---QVVGLRYFNVYGPGEQHKGSMASVAYHLNNQMHETGKINLFAGCDGYEDGEQRRDFV 217

		                 GLR+F VYGP    +  MA   +     M E   I++      Y  G+ +RDF 

		Sbjct: 169 YGLPATGLRFFTVYGP--WGRPDMA--LFKFTKAMLEGKSIDV------YNYGKMKRDFT 218

		

		Query: 218 YVGDVVKANL------------WFLEHADVSG------IFNIGTGASQSFNDVARAVIDW 259

		           Y+ D+ +A +            W +E    +       ++NIG  +     D  +A+ D 

		Sbjct: 219 YIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDA 278

		

		Query: 260 HGR-GELNYIPFPEHLKGAYQSFTEADIHDLRH-VGFDERFLTVEEGVKLYLDW 311

		            G   + N +P            T AD   L   +GF     TV++GVK +++W

		Sbjct: 279 LGIEAKKNMLPLQP----GDVLETSADTKALYEVIGFTPE-TTVKDGVKNFVNW 327

		

		

		>ARGDEIMINASE#Bacterial arginine deiminase signature.

		          Length = 409

		

		 Score = 30.6 bits (69), Expect = 0.008

		 Identities = 19/91 (20%), Positives = 32/91 (35%), Gaps = 13/91 (14%)

		

		Query: 165 VELEDGDAE-LAKQVAMHVAASNPMVVNPEDMPAEIVEKEKEIIKAQPDMAGKPDNIIEK 223

		             +ED  +E L   VA+     +  ++  E      +   K+   +        DN+I K

		Sbjct: 70  EYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINLLKDYFSSLT-----IDNMISK 124

		

		Query: 224 MMGG-------RINKFLAENALVGQPFVIDP 247

		           M+ G            L +       F+IDP

		Sbjct: 125 MISGVVTEELKNYTSSLDDLVNGANLFIIDP 155

		

		

		>CARBMTKINASE#Bacterial carbamate kinase signature.

		          Length = 314

		

		 Score = 32.9 bits (75), Expect = 8e-04

		 Identities = 18/85 (21%), Positives = 29/85 (34%), Gaps = 25/85 (29%)

		

		Query: 102 VPARIMSAIPMSGLVDHYDRRKAMHHLSEGRVVIFAAGTGNPLVTT-------------D 148

		            P   + A  +  LV+             G +VI + G G P++               D

		Sbjct: 169 DPKGHVEAETIKKLVER------------GVIVIASGGGGVPVILEDGEIKGVEAVIDKD 216

		

		Query: 149 SAASLRGIEVDVDLLLKATRVDGVY 173

		            A      EV+ D+ +  T V+G  

		Sbjct: 217 LAGEKLAEEVNADIFMILTDVNGAA 241

		

		

		>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein

		           signature.

		          Length = 533

		

		 Score = 36.5 bits (84), Expect = 3e-04

		 Identities = 16/40 (40%), Positives = 17/40 (42%)

		

		Query: 450 AFTQQVTQAIQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 489

		           AF  Q+        QAQ Q     Q QAQA AQ    A A

		Sbjct: 325 AFVNQIHLNFVMPPQAQQQQGQGQQQQAQATAQEAVAAAA 364

		

		

		

		 Score = 30.7 bits (69), Expect = 0.019

		 Identities = 14/41 (34%), Positives = 16/41 (39%)

		

		Query: 450 AFTQQVTQAIQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 490

		           +F   +  A   Q         QAQ Q     Q QAQA AQ

		Sbjct: 317 SFDGYINNAFVNQIHLNFVMPPQAQQQQGQGQQQQAQATAQ 357

		

		

		>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family

		           signature.

		          Length = 290

		

		 Score = 29.8 bits (67), Expect = 0.023

		 Identities = 17/109 (15%), Positives = 44/109 (40%), Gaps = 11/109 (10%)

		

		Query: 17  LSGVTVAMALVPEAVAFSLVAHVAPLVGLYAAFIMCTLAAILGGRPGMISGATGAMAVVI 76

		             G+   +     ++  +++  +A  + L+    +     +L G+ GM  G         

		Sbjct: 167 WGGLLFNLLGGFVSLGDAVIGAMAGYLVLW---SLYWAFKLLTGKEGMGYGD-------- 215

		

		Query: 77  VGLVSQYPGWQGLQYLFVTIIMTGILEILIGVLRLGRVVRMLPQPVMFG 125

		             L++    W G Q L + ++++ ++   +G+  +        +P+ FG

		Sbjct: 216 FKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFG 264

		

		

		>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein

		           signature.

		          Length = 522

		

		 Score = 30.9 bits (69), Expect = 0.007

		 Identities = 29/122 (23%), Positives = 63/122 (51%), Gaps = 24/122 (19%)

		

		Query: 99  KQKHQGHQEHQESQKQSGSKLRAERTKIHSLRLKLLEAISSHKHVKSKENISLL-----E 153

		           +++ +  ++ Q++QK    K + ER K  +    L  A+S+ +++ + +N+S L     E

		Sbjct: 149 EKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRE 208

		

		Query: 154 AELEQKDQLLEEKQ-------RKVEELQQQLLEQ------------KSEKAEAGPEDCSS 194

		            EL+Q ++L + ++       +++EEL ++  E+            K++K++  PED S 

		Sbjct: 209 NELDQMERLEDMQEQAQANALKQIEELNKKQAEEAVRQRAKDKISIKTDKSQKSPEDNSI 268

		

		Query: 195 RL 196

		            L

		Sbjct: 269 EL 270

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 32.5 bits (74), Expect = 0.003

		 Identities = 48/312 (15%), Positives = 94/312 (30%), Gaps = 30/312 (9%)

		

		Query: 47  IIISPFAGRLVDAKGSITCIQYSSILCFFLTIGLIFTNSYFILFALVFIRSSLKTVFFPA 106

		              +P  G L D  G    +  S          +      ++L+ +  I + +       

		Sbjct: 57  FACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLY-IGRIVAGITGATGAV 115

		

		Query: 107 LSRIIKLTVDKKQLLSVNSLIQFNANGLLIIAPIIGMVVFSTLGKKWCFLITSILFFLTF 166

		               I    D  +       +       ++  P++G ++         F   + L  L F

		Sbjct: 116 AGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLM-GGFSPHAPFFAAAALNGLNF 174

		

		Query: 167 GLSFFLKEVSDKC-----SKIAMGPLSQGDLDIKKLLVPFLGMIIAAFAIYL-------- 213

		               FL   S K       + A+ PL+       + +     ++   F + L        

		Sbjct: 175 LTGCFLLPESHKGERRPLRREALNPLAS--FRWARGMTVVAALMAVFFIMQLVGQVPAAL 232

		

		Query: 214 ----GDSLFPVLLKSIGLDFKDFALIGSFFGIGGMAASIFCQCYKNSNEVTLIKLGATLV 269

		               G+  F     +IG+    F ++ S        A I         E   + LG    

		Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLA-----QAMITGPVAARLGERRALMLGMIAD 287

		

		Query: 270 IISMFTYGAFSSMLSQRVFFVFAMLNAGGITLISISSATLLQKNTPTHMMGKVSSINTMI 329

		                     +       F +  +L +GGI + ++    +L +       G++      +

		Sbjct: 288 GTGYILLAFATR--GWMAFPIMVLLASGGIGMPALQ--AMLSRQVDEERQGQLQGSLAAL 343

		

		Query: 330 FGLASIIIPMLG 341

		             L SI+ P+L 

		Sbjct: 344 TSLTSIVGPLLF 355

		

		

		>ANTHRAXTOXNA#Anthrax toxin LF subunit signature.

		          Length = 800

		

		 Score = 36.3 bits (83), Expect = 9e-04

		 Identities = 24/63 (38%), Positives = 34/63 (53%), Gaps = 16/63 (25%)

		

		Query: 16  QKLLNKIQAVVPEVSELYSEY---VYFVDVN-------RELAADEKNSLNSLLHYGEMAP 65

		           Q LL KI     +V E+YSE    +YF D++       ++L+ +EKNS+NS    GE  P

		Sbjct: 83  QDLLKKIPK---DVLEIYSELGGEIYFTDIDLVEHKELQDLSEEEKNSMNS---RGEKVP 136

		

		Query: 66  VLS 68

		             S

		Sbjct: 137 FAS 139