>PF08280#M protein trans-acting positive regulator Length = 530 Score = 802 bits (2073), Expect = 0.0 Identities = 522/530 (98%), Positives = 522/530 (98%) Query: 1 MISIFSLDRIEIGEYTYQRLIWLSKCRKRGPLYLIEKYLESSIESKCQLVVLFFKTSYLP 60 MISIFSLDRIEIGEYTYQRLIWLSKCRKRGPL LIEKYLESSIESKCQLVVLFFKTS LP Sbjct: 1 MISIFSLDRIEIGEYTYQRLIWLSKCRKRGPLSLIEKYLESSIESKCQLVVLFFKTSSLP 60 Query: 61 ITEVAEKTGLTFLQLNHYCEELNAFFPGSLSMTIQKRMISCQFTHPFKETYLYQLYASSN 120 ITEVAEKTGLTFLQLNHYCEELNAFFP SLSMTIQKRMISCQFTHP KETYLYQLYASSN Sbjct: 61 ITEVAEKTGLTFLQLNHYCEELNAFFPDSLSMTIQKRMISCQFTHPSKETYLYQLYASSN 120 Query: 121 VLQLLAFLIKNGSHSRPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEY 180 VLQLLAFLIKNGSHSRPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEY Sbjct: 121 VLQLLAFLIKNGSHSRPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEY 180 Query: 181 RIRYLIALLYSKFGIKVYDLTQQDKNTIHSFLSHSSTHLKTSPWLSESFSFYDILLALSW 240 RIRYLIALLYSKFGIKVYDLTQQDKN IHSFLSHSSTHLKTSPWLSESFSFYDILLALSW Sbjct: 181 RIRYLIALLYSKFGIKVYDLTQQDKNIIHSFLSHSSTHLKTSPWLSESFSFYDILLALSW 240 Query: 241 KRHQFSVTIPQTRIFQQLKKLFVYDSLKKSSHDIIETYCQLNFSAGDLDYLYLIYITANN 300 KRHQFSVTIPQTRIFQQLKKLFVYDSLKKSS DIIETYCQLNFSAGDLDYLYLIYITANN Sbjct: 241 KRHQFSVTIPQTRIFQQLKKLFVYDSLKKSSRDIIETYCQLNFSAGDLDYLYLIYITANN 300 Query: 301 SFASLQWTPEHTRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFN 360 SFASLQWTPEH RQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFN Sbjct: 301 SFASLQWTPEHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFN 360 Query: 361 LQHFIPETNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKHFHLFCHYVEQILR 420 LQHFIPETNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKHFHLFCHYVEQILR Sbjct: 361 LQHFIPETNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKHFHLFCHYVEQILR 420 Query: 421 NIQPPLVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITH 480 NIQPPLVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITH Sbjct: 421 NIQPPLVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITH 480 Query: 481 SQLIPFVQHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT 530 SQLIPFV HELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT Sbjct: 481 SQLIPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT 530
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 31.1 bits (70), Expect = 0.010 Identities = 18/85 (21%), Positives = 27/85 (31%), Gaps = 5/85 (5%) Query: 275 PPRPGETPEYGPKTPELDGSPIPEDPKHPDDNLEPTLPPVMLDGEEVPEVPSESLEPALP 334 PP+ + P PE + PIPE PK +E P + P + +E Sbjct: 62 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPK-----PKPKPKPVKKVEQPKR 116 Query: 335 PLMPELDGQEVPEVPSESLEPALPP 359 + P P + P Sbjct: 117 DVKPVESRPASPFENTAPARPTSST 141
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 26.4 bits (58), Expect = 0.031 Identities = 10/29 (34%), Positives = 20/29 (68%), Gaps = 1/29 (3%) Query: 10 RFVYLLVALFAALLLIARP-VMADEENDP 37 F+ ++ +FA +L+I+ P V+A+ + DP Sbjct: 5 LFISRVILIFALILVISTPNVLAESQPDP 33
>PF05844#YopD protein Length = 295 Score = 26.5 bits (58), Expect = 0.013 Identities = 10/39 (25%), Positives = 20/39 (51%), Gaps = 1/39 (2%) Query: 13 SKDLPVATKVAAHRGKKAFEENTAFATDLMKEVSRLITQ 51 +++ V + + +K E+ +F MK+V +LI Q Sbjct: 242 AREEEVNATIGQSQKQKV-EDQMSFDAGFMKDVLQLIQQ 279
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 90.7 bits (225), Expect = 8e-22 Identities = 42/160 (26%), Positives = 64/160 (40%), Gaps = 24/160 (15%) Query: 264 DIDWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGS 323 + D D HG HV G +A +G+APEA ++ ++V G Sbjct: 74 EGDPEIFKDY---NGHGTHVAGTIAAT-----ENENGVVGVAPEADLLIIKVLNKQGSGQ 125 Query: 324 AESLFIKAIEDAVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNER 383 + + I+ I A+ D+I++SLG L EA++KA + + V+ AAGNE Sbjct: 126 YDWI-IQGIYYAIEQKVDIISMSLGGP-----EDVPELHEAVKKAVASQILVMCAAGNEG 179 Query: 384 VYGSDHDDPLATNPDYGLVGSPSTGRTPTSVAAINSKWVI 423 D+ +G P SV AIN Sbjct: 180 DGDDRTDE----------LGYPGCYNEVISVGAINFDRHA 209 Score = 77.6 bits (191), Expect = 2e-17 Identities = 36/147 (24%), Positives = 58/147 (39%), Gaps = 18/147 (12%) Query: 561 FDSVVSKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMAS 620 ++ V+S + FSN + D+ APG DI ST Y + +GTSMA+ Sbjct: 194 YNEVISVGAINFDRHASEFSNSNN------EVDLVAPGEDILSTVPGGKYATFSGTSMAT 247 Query: 621 PQIAGASLLVKQ-YLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGL 679 P +AGA L+KQ + +L + L+ SP+ +G GL Sbjct: 248 PHVAGALALIKQLANASFERDL----TEPELYAQLIKRT-------IPLGNSPKMEGNGL 296 Query: 680 LNIDGAVTSGLYVTGKDNYGSISLGNI 706 L + + G +S ++ Sbjct: 297 LYLTAVEELSRIFDTQRVAGILSTASL 323 Score = 39.8 bits (93), Expect = 3e-05 Identities = 11/34 (32%), Positives = 18/34 (52%), Gaps = 1/34 (2%) Query: 129 HDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS 162 + ++ W++ G+G VAV+DTG D H Sbjct: 26 VEMIQAPAVWNQTR-GRGVKVAVLDTGCDADHPD 58
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 38.5 bits (89), Expect = 2e-05 Identities = 42/170 (24%), Positives = 70/170 (41%), Gaps = 27/170 (15%) Query: 93 INTSLDKTKGELSQLTPELKDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADL 152 IN L + G L+ PEL +V ++ A IP N++VYR G L Sbjct: 295 INNYL-ISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRS--------GPQEFGL 345 Query: 153 TSYYRNHQFDPHILCKIK---------LGTRYTKHSFMSTT--ALKNGAMTHRPVEVRIC 201 T + F+ KI+ G T +F+ST+ ++ A R + +RI Sbjct: 346 TLTSPEYDFN-----KIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRIN 400 Query: 202 VKKGAKAAFVEPYSAVPSEVELLFPRGCQLEV--VGAYVSQDHKKLHIEA 249 + K + A++ E E+L G + ++ V +Y KL ++A Sbjct: 401 IPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDA 450
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 27.7 bits (61), Expect = 0.040 Identities = 12/66 (18%), Positives = 19/66 (28%), Gaps = 1/66 (1%) Query: 162 KLKDSQTLKKEKEKKERQLAEEKQIEEERKHVEQKQLEESM-LKQIREEDHKPWHQRLSE 220 L+ + K + L EK RK +K LE +M K + Sbjct: 128 ALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAA 187 Query: 221 SIQQDQ 226 + Sbjct: 188 LEARQA 193
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 100 bits (249), Expect = 1e-27 Identities = 68/252 (26%), Positives = 111/252 (44%), Gaps = 24/252 (9%) Query: 3 KVVLVTGCASGIGYAQARYFLSQGYHVYGVDKSDKPDLNGNFHFIKLDLSSELSPL---- 58 K+ +TG A GIG A AR SQG H+ VD + + +E P Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 59 -----------FKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVKLTRHY 107 + + +DIL N AG+L + +SDEE E F +N +R Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 108 LRHMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQIHIFGIAP 167 ++M++++SG I+ + S + + AY SSK A FT+ L L+ A+ I ++P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 168 GAVKTAM-----TASDFEP---GGLADWVARETPIGRWTEPSEVAELTGFLASGKTRSMQ 219 G+ +T M + G + P+ + +PS++A+ FL SG+ + Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 220 GEIVKIDGGWTL 231 + +DGG TL Sbjct: 248 MHNLCVDGGATL 259
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.3 bits (78), Expect = 0.001 Identities = 40/205 (19%), Positives = 71/205 (34%), Gaps = 15/205 (7%) Query: 91 ANYNQHGQATTLTVQAPASSPASVSHVPSSEPLPQASATSQSTVPMAPSATP--SDVPTT 148 +N + + V PA + S + +E Q S T + A T +V Sbjct: 1012 SNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKE 1071 Query: 149 PFASAKPDSSVTASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAE----TTEVEP 204 ++ K ++ ++ S T + T + E+ + + V T K E T++V P Sbjct: 1072 AKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSP 1131 Query: 205 KTDISEDSTSANRPVPNESASEEVSSAAPAQAPAEKEETSQMLTAPAAQKAVADTTSVAT 264 K + SE P + + P + T+ PA + + V Sbjct: 1132 KQEQSETVQPQAEPARENDPTVN------IKEPQSQTNTTADTEQPAKETSSNVEQPVTE 1185 Query: 265 SNGLSYAPNHAYNPMN---AGLQPQ 286 S ++ + NP N A QP Sbjct: 1186 STTVNTGNSVVENPENTTPATTQPT 1210 Score = 33.1 bits (75), Expect = 0.002 Identities = 30/172 (17%), Positives = 55/172 (31%), Gaps = 14/172 (8%) Query: 98 QATTLTVQAPASSPASVSHVPSSEPLPQASATSQSTVPMAPSATPSDVPTTPFASAKPDS 157 + +T Q S + P +EP + T P + + T +D P + Sbjct: 1121 EVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT-EQPAKETSSNV 1179 Query: 158 SVTASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETTEVEPKTDISEDSTSANR 217 + T +T + E PE A P + +PK + R Sbjct: 1180 EQPVTESTTVNTGNSVVE-------NPENTTPATTQPTVNSESSNKPKN----RHRRSVR 1228 Query: 218 PVPNESASEEVSSAAPAQAPAEKEETSQMLTAPAAQKAVADTTSVATSNGLS 269 VP E ++++ ++ + + T A A VA + G + Sbjct: 1229 SVP--HNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKA 1278
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 32.1 bits (73), Expect = 0.003 Identities = 31/138 (22%), Positives = 59/138 (42%), Gaps = 17/138 (12%) Query: 1 MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTETEQIVFIDTP 60 ++ SG + LG + G + N ++ ++ I T+ + E ++ IDTP Sbjct: 24 LYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS-------FQWENTKVNIIDTP 76 Query: 61 GIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERLKAAKIPVILVIN 120 G H DF+ E Y +L ++ + ++ A + ++ L+ IP I IN Sbjct: 77 G-HM------DFLAE-VYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFIN 128 Query: 121 KIDK--VHPDQLLAQIDD 136 KID+ + + I + Sbjct: 129 KIDQNGIDLSTVYQDIKE 146
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.5 bits (87), Expect = 3e-05 Identities = 23/137 (16%), Positives = 49/137 (35%), Gaps = 10/137 (7%) Query: 3 IFVLEDDFLHQTRIGKIIYKILTDNKLEVNHLEVYGKPNQLLEDISERGRHQLFFLDIDI 62 I V +DD I ++ + L+ +V + L I+ G L D+ + Sbjct: 6 ILVADDD----AAIRTVLNQALSRAGYDV---RITSNAATLWRWIA-AGDGDLVVTDVVM 57 Query: 63 KGEDKKGMEIAVEIRNRDPHAVIVFVTTHSEFMPVSFQYQVSALDFIDKELPEELFSHRI 122 E+ ++ I+ P ++ ++ + FM + A D++ K I Sbjct: 58 PDEN--AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115 Query: 123 EKAITYVQDNQGKTLAE 139 +A+ + K + Sbjct: 116 GRALAEPKRRPSKLEDD 132
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.0 bits (91), Expect = 7e-06 Identities = 17/139 (12%), Positives = 52/139 (37%), Gaps = 4/139 (2%) Query: 22 RIKIDILKTQFLQNASQQLTTVENQITELKDQIEQANIQLKNNIIIAPETGTIHLNSEFE 81 + + ++ F +L + I L ++ + + + ++I AP + + Sbjct: 286 KEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHT 345 Query: 82 GKSLIPNGSEVAQIYPDIQKIKEVFITYYVTSEHVSLLKEKQGVRLSLEKV-GNQTLTIN 140 ++ + I P+ ++ +T V ++ + + Q + +E + + Sbjct: 346 EGGVVTTAETLMVIVPEDDTLE---VTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLV 402 Query: 141 GTIQTIDKSATKTDQGNLF 159 G ++ I+ A + + L Sbjct: 403 GKVKNINLDAIEDQRLGLV 421
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 6e-08 Identities = 24/103 (23%), Positives = 50/103 (48%), Gaps = 9/103 (8%) Query: 34 VLLVSFLVLF---SLFAKKEITITSQGEMTP---TKVIASVQSTSDHTIVVNNLKNNKFI 87 ++ FLV+ S+ + EI T+ G++T +K I ++++ I+V K + + Sbjct: 62 YFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIV---KEGESV 118 Query: 88 KKGDVIIQYSKTMENSQKKALEKQLATLNKQKNGLQILKTSLE 130 +KGDV+++ + + + L ++ QIL S+E Sbjct: 119 RKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIE 161
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.8 bits (228), Expect = 1e-23 Identities = 29/133 (21%), Positives = 65/133 (48%), Gaps = 1/133 (0%) Query: 3 KILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLE 62 IL+ DD+ I ++ L++ GYD+ + DL++ D+++P+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 VAKEIRKT-SHVPIIMLSAKDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTET 121 + I+K +P++++SA+++ + E GA DY+ KPF EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 IETAVAEENASSG 134 + + +++ Sbjct: 125 RPSKLEDDSQDGM 137
>PF06580#Sensor histidine kinase Length = 349 Score = 44.5 bits (105), Expect = 5e-07 Identities = 30/187 (16%), Positives = 72/187 (38%), Gaps = 34/187 (18%) Query: 253 DETNRMMRMISDLL--NLSRIDNQVTQLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVY 310 + M+ +S+L+ +L + + LA E+T +++ +F +++ ++ Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQF---EDRLQFENQIN 247 Query: 311 EIVRDYPITSVWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQG 370 + D + + ++ ++EN + + I P GGKI ++ + + + + + G Sbjct: 248 PAIMDVQVPPMLVQT-------LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG 300 Query: 371 LGIPKTDLPLIFDRFYRVDKARSRAQGGTGLGLAIAKEIIKQHHGF---IWAKSDYGKGS 427 K + TG GL +E ++ +G I GK Sbjct: 301 SLALKNT------------------KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV- 341 Query: 428 TFTIVLP 434 +++P Sbjct: 342 NAMVLIP 348
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 48.5 bits (115), Expect = 1e-07 Identities = 48/313 (15%), Positives = 95/313 (30%), Gaps = 10/313 (3%) Query: 209 AKVAKQFLELDANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSMEED 268 + VA + + Q + D + + + + + + AL+ + + +E Sbjct: 41 SAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEK 100 Query: 269 YQKFKQKKQVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQ---EAEKKAEAKKHL 325 +K + + + + + +L K + + E A K L Sbjct: 101 LRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL 160 Query: 326 EQLQEQLDGFQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEF 385 E+ E F + + + L L + +L + FS+ ++TL E Sbjct: 161 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 220 Query: 386 VLLMQKEAALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQK 445 L ++A L L + + E L + +L + A A Sbjct: 221 AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 280 Query: 446 EQVEMLLQNYQEGDKRVQELERDYQLNQERLFDLLDQ-------KKGKEARKASLESIQK 498 +++ L + +LE Q+ L KK EA LE K Sbjct: 281 AKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNK 340 Query: 499 SHSQFYAGVRAVL 511 +R L Sbjct: 341 ISEASRQSLRRDL 353 Score = 30.4 bits (68), Expect = 0.044 Identities = 38/243 (15%), Positives = 88/243 (36%), Gaps = 18/243 (7%) Query: 169 KYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLELDANRKQLQLD 228 + + + LE L+ + A LEK + A F ++ Sbjct: 229 DLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTA----DSAKIK 284 Query: 229 ILVKDIDIAQERQTKDTEALAALQ-------QDLASYYAKRQSMEEDYQKFKQKKQVLSQ 281 L + + + L +DL + ++ +E ++QK +++ ++ Sbjct: 285 TLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEA 344 Query: 282 ESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDGFQAEEKQ 341 + L + LE + + ++ E+ ++ + L+ LD + +KQ Sbjct: 345 SRQSLRRDLDASREAKKQLEAEHQKLE-------EQNKISEASRQSLRRDLDASREAKKQ 397 Query: 342 RTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKEAALSNQLTA 401 + L + +L +++ EL + + + +L L E L +K A + +L Sbjct: 398 VEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAK 457 Query: 402 LKA 404 L+A Sbjct: 458 LRA 460
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.3 bits (89), Expect = 4e-05 Identities = 28/141 (19%), Positives = 59/141 (41%), Gaps = 13/141 (9%) Query: 52 SVIGVLFNLFGGVIADSFKR----KKIIITTNILCGTACLVLSFLTKEQWLVYAIVLTNV 107 + G+L +L +I ++ ++ I GT ++L+F T W+ + I+ V Sbjct: 253 AAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT-RGWMAFPIM---V 308 Query: 108 ILAFMSAFSSPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYKLLGIHGV 167 +LA P+ +A V ++ QL L +++ + P++ +Y + Sbjct: 309 LLAS-GGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA----ASI 363 Query: 168 LLLDGLSFLIAALLISFILPV 188 +G +++ A L LP Sbjct: 364 TTWNGWAWIAGAALYLLCLPA 384
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 25.4 bits (55), Expect = 0.021 Identities = 10/45 (22%), Positives = 18/45 (40%), Gaps = 5/45 (11%) Query: 9 EIGHIFPSNLNKEEKSRVYSWAEKLHQILQLNHITTHTEFRIGRN 53 E+GHI + K +Y+ L+H++ I +N Sbjct: 357 ELGHILGAEHTDNSKDLMYATFTG-----YLSHLSEKNMDIIAKN 396
>PF06580#Sensor histidine kinase Length = 349 Score = 26.0 bits (57), Expect = 0.021 Identities = 7/45 (15%), Positives = 19/45 (42%) Query: 29 LFLAIAIFGMMVTVSYFSYRDARQYYESQITGLRTQLSRTQKQLK 73 + + + M ++ YF + + Y +++I + + QL Sbjct: 120 IIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLM 164
>PRPHPHLPASEC#Prokaryotic zinc-dependent phospholipase C signature. Length = 398 Score = 29.6 bits (66), Expect = 0.016 Identities = 32/180 (17%), Positives = 65/180 (36%), Gaps = 14/180 (7%) Query: 109 NKIRQKEPKSVDDNLKLLVNSFGNELSSYLYGADWSDTKYDLAVEIINKHDVFSGYKQTE 168 N + + EP+SV NL++L +EL D+ YDL + D + + + Sbjct: 52 NDLSKNEPESVRKNLEIL-KENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDN 110 Query: 169 TYKKADKPYDEGELEKNKKLTQLEQLQQLGRLQQL-----EQLQQLGRLQQLEQLQQLGR 223 ++ A D GE + K Q G +Q E + G + + Sbjct: 111 SWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTA 170 Query: 224 LQQLGRLEQLEPTNYSYEAFSDIEDAIFYLDPPYENTTQKSYKGDFNSQAFYDWAFGMSK 283 + G ++ +E F++ + ++ T + Y ++ F W+ ++ Sbjct: 171 VDSAGHVK--------FETFAEERKEQYKINTAGCKTNEDFYADILKNKDFNAWSKEYAR 222
>SSPAMPROTEIN#Salmonella surface presentation of antigen gene type M signature. Length = 147 Score = 28.9 bits (64), Expect = 0.036 Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 6/65 (9%) Query: 387 ERINALENNQKVITNNQKQFELNLPKYLNDINGKRVWYEKPDDNIEHKIGDYWFEKNGKY 446 E I AL Q ++ K EL + + I KR EK + + K YW K G Y Sbjct: 66 EEIYALLRKQSIVRRQIKDLELQIIQ----IQEKRSELEKKREEFQEK-SKYWLRKEGNY 120 Query: 447 QRTWI 451 QR WI Sbjct: 121 QR-WI 124
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 563 bits (1452), Expect = 0.0 Identities = 336/336 (100%), Positives = 336/336 (100%) Query: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL 60 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL Sbjct: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL 60 Query: 61 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI 120 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI Sbjct: 61 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI 120 Query: 121 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA 180 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA Sbjct: 121 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA 180 Query: 181 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA 240 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA Sbjct: 181 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA 240 Query: 241 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQID 300 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQID Sbjct: 241 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQID 300 Query: 301 GNLKLKNPTADDHAATKAYVDSEVKKLKALLMDKQV 336 GNLKLKNPTADDHAATKAYVDSEVKKLKALLMDKQV Sbjct: 301 GNLKLKNPTADDHAATKAYVDSEVKKLKALLMDKQV 336
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.6 bits (77), Expect = 0.003 Identities = 27/145 (18%), Positives = 51/145 (35%), Gaps = 21/145 (14%) Query: 158 RLSSSYQSGINGLKAQLANDKI---GLQAEIQATAQGLSQKYDNELRQLSAKITTTSSGT 214 RL+S + + + Q ++ +AE T +Y+N R +++ SS Sbjct: 186 RLTSLIKEQFSTWQNQKYQKELNLDKKRAERL-TVLARINRYENLSRVEKSRLDDFSSLL 244 Query: 215 TEAYESKLAGLRAEFTRSNQGMRIELESQISGLRAVQQSTASQISQEIRDRTGAVSRVQQ 274 + +K A L E E++ + SQ+ Q + A Q Sbjct: 245 HKQAIAKHAVL-------------EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL 291 Query: 275 DLESYQR----RLQDAEDNYSSLTH 295 + ++ +L+ DN LT Sbjct: 292 VTQLFKNEILDKLRQTTDNIGLLTL 316
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 26.0 bits (57), Expect = 0.043 Identities = 16/63 (25%), Positives = 25/63 (39%), Gaps = 8/63 (12%) Query: 3 PLIQSLTEGQLR-SDIPNFRPGDTVRVHAKVVE-------GTRERIQIFEGVVISRKGQG 54 ++ + +L DI R GD +R+H V G R++ GVV + Sbjct: 260 DVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIGNRKKFLCQPGVVGKKIAAQ 319 Query: 55 ISE 57 I E Sbjct: 320 ILE 322
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 247 bits (633), Expect = 4e-78 Identities = 130/442 (29%), Positives = 224/442 (50%), Gaps = 7/442 (1%) Query: 1 MLDVSEVSIDQLCQETELKKQRVYNLLIEMIKDLEDTLTLTICDDTVSIPYKTYQLKMPY 60 S + I ++ ++T L ++ + E+ D+L++TI +S + T+ K Y Sbjct: 53 FFKTSSLPITEVAEKTGLTFLQLNHYCEELNAFFPDSLSMTIQKRMISCQF-THPSKETY 111 Query: 61 FKKLYQTSIFLKMLCFLIE--PGELSLHDFIKREYISQATAYRIRTNCRKYLKKVGLNVR 118 +LY +S L++L FLI+ L DF + ++S ++AYR+R L+ L + Sbjct: 112 LYQLYASSNVLQLLAFLIKNGSHSRPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLS 171 Query: 119 QNHVVGPEYRIRFLIALLHYQFGMTIYDFDKTSMNKVVSLIINSNQAITLNDASKAPYEF 178 +N +VG EYRIR+LIALL+ +FG+ +YD + N + S + +S+ L + F Sbjct: 172 KNKIVGEEYRIRYLIALLYSKFGIKVYDLTQQDKNIIHSFLSHSS--THLKTSPWLSESF 229 Query: 179 SYFAILISLIWKRQHGNLGIPQTDAFKHLKKLSIYHDIKMTSQEIIGKWYHPDLTDEDLD 238 S++ IL++L WKR ++ IPQT F+ LKKL +Y +K +S++II + + + DLD Sbjct: 230 SFYDILLALSWKRHQFSVTIPQTRIFQQLKKLFVYDSLKKSSRDIIETYCQLNFSAGDLD 289 Query: 239 YIFLCFCTTNNPFHKDKWTPKKVKELFELVMTKTNGKTLKASLRPLLGDNILNSLPFKRI 298 Y++L + T NN F +WTP+ +++ +L + L + LL + + Sbjct: 290 YLYLIYITANNSFASLQWTPEHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKA 349 Query: 299 LVSFSRLFISNLQVLLPDIHLFHYLRRQQKRNKSFYNTLKTIVEEWMSAEGIVGKLPSYH 358 L+ FS+ F+ NLQ +P+ +LF + K N+ Y +LK IVEEWM+ L H Sbjct: 350 LMFFSKSFLFNLQHFIPETNLF--VSPYYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKH 407 Query: 359 LLLFTIQLEELLKTYLPPIPVYLLTNNTAALDLMTNALSIYFPPAIATVMPVNVEIIPFK 418 LF +E++L+ PP+ V + +N L+T++ YF + Sbjct: 408 FHLFCHYVEQILRNIQPPLVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVY 467 Query: 419 DIVKEKQSVIIADRQYLNLIQH 440 I K ++I Q + + H Sbjct: 468 QIPDLKPDLVITHSQLIPFVHH 489
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.8 bits (69), Expect = 0.045 Identities = 51/259 (19%), Positives = 97/259 (37%), Gaps = 7/259 (2%) Query: 1070 KAYRPGEAVKARKEAAKADLEREAAKVR-EAIANDPTLTKADKAKQTEAVAKALKAAIAA 1128 +A + A A + AKA R+A R + I N+ A + +A A AA+ A Sbjct: 66 QAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRHNASRTPSATELAHANNAAMQA 125 Query: 1129 VDKATTAEGINQELGKGITAINKAYRPGEAVKARKEAAKANLEKVAKETKALISGDRYLS 1188 D+ ++ K A KA++ E + E KA E+ K +A LS Sbjct: 126 EDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALS 185 Query: 1189 ETEKAVQKQAVEQALAKA---LGQVEAAKTVEAVKLAENLGTVAIRSAYVAGLAKDTDQA 1245 E KAV + ++ L+ A + +++ +L+ ++ +AG + QA Sbjct: 186 EEAKAV--EIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQA 243 Query: 1246 TAALNEAKQAAIEALKQAAAETLAKITTDAKLTEAQKAEQSENVSLALKTAIATVRSAQS 1305 +A E + + +A + +A + E + + + + Sbjct: 244 SAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINA 303 Query: 1306 -IASVKEAIDKGITAIRAA 1323 I +++AI + A Sbjct: 304 DITQIQKAISQVSNNRNAG 322
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 31.3 bits (71), Expect = 0.003 Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 1/76 (1%) Query: 37 SYQDFLDVLLSLFQFVIIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIE 96 S + ++ L S+ + V++ ++++ NL +L T L +L + +I Sbjct: 133 SIKSLVEFLKSILKVVLLSILIWII-IKGNLVTLLQLPTCGIECITPLLGQILRQLMVIC 191 Query: 97 MTLLVLILIFDVLLQK 112 V+I I D + Sbjct: 192 TVGFVVISIADYAFEY 207
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 31.8 bits (72), Expect = 0.004 Identities = 23/117 (19%), Positives = 46/117 (39%), Gaps = 3/117 (2%) Query: 255 FVPTSLLLIIFFLFSLLAIGF---GLLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLS 311 + LL + +L + F G+++ A+ + L++ P L+G ++P+ Sbjct: 141 YTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVD 200 Query: 312 ITPSYMQAIGKLLPQNWVLSAIAIFQSGGTLSQAWPHLLALMGTALALIIFSSLLLK 368 P Q + LP + + I G + H+ AL + S+ LL+ Sbjct: 201 QLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLR 257
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 133 bits (336), Expect = 2e-38 Identities = 74/344 (21%), Positives = 136/344 (39%), Gaps = 44/344 (12%) Query: 4 NIIVTGGAGFIGSNFVHY-VYNNHPDVHVTVLDKLT--YAGN--RANIEAILGDRVELVV 58 +VTG AGFIG + + H V +D L Y + +A +E + + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGH---QVVGIDNLNDYYDVSLKQARLELLAQPGFQFHK 58 Query: 59 GDIADAELVDKLAA--KADAIVHYAAESHNDNSLEDPSPFIHTNFIGTYTLLEAARKYDI 116 D+AD E + L A + + SLE+P + +N G +LE R I Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 117 RFHHV--STDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYSSTKAASDLIVKAWV 174 + H + S+ VYG L +P + + +P S Y++TK A++L+ + Sbjct: 119 Q-HLLYASSSSVYG---LNRKMPFSTDDSVD--------HPVSLYAATKKANELMAHTYS 166 Query: 175 RSFGVKATISNCSNNYGPYQHIEKFIPRQITNILAGIKPKLYGEGKNVRDWIHTNDHSTG 234 +G+ AT YGP+ + + + +L G +Y GK RD+ + +D + Sbjct: 167 HLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEA 226 Query: 235 VWAIL------------------TKGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAY 276 + + Y IG + ++ + + +G Sbjct: 227 IIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKK- 285 Query: 277 DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWY 320 + + + G L + D+ L E +G+ P+ T +G++ + WY Sbjct: 286 NMLPLQPGDVLETSADTKALYEVIGFTPE-TTVKDGVKNFVNWY 328
>SECA#SecA protein signature. Length = 901 Score = 29.5 bits (66), Expect = 0.028 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Query: 165 VIKH-YEKLAKGKQAIVYTHSVEASHLVSDTFNQAGYQSQSVSGKTSKSEREEAMQAFRD 223 +I+ E+ AKG+ +V T S+E S LVS+ +AG + ++ K +E QA Sbjct: 438 IIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYP 497 Query: 224 GKLRILVN 231 + I N Sbjct: 498 AAVTIATN 505
>PF05272#Virulence-associated E family protein Length = 892 Score = 25.4 bits (55), Expect = 0.046 Identities = 14/55 (25%), Positives = 19/55 (34%), Gaps = 4/55 (7%) Query: 10 TPQKTGKKDKLGNDITKDVVKRDAKGRFTEWSADDVSLYGRDLTSSARKLLTNQV 64 P+K G D D + F EW D+V+ L R LL + Sbjct: 402 PPKKRDPSAGAGTDPGGPGGGDDGEDPFGEWLDDEVA----RLRLRGRWLLKPRR 452
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 39.7 bits (92), Expect = 5e-05 Identities = 32/139 (23%), Positives = 56/139 (40%), Gaps = 9/139 (6%) Query: 294 VFSQLYLESFWGDTPVGRAD----NNWGGI----TWTGATTRPSGINVSQGQPRAEGGHY 345 + +Q LES WG + R + N G+ W G T + G+ + + Sbjct: 174 ILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKF 233 Query: 346 NHYASVDDYLKDYTYLLAEQGIY-AVKGKLTIDEYTRGLFRVGGATYDYAAAGYDHYAPL 404 Y+S + L DY LL Y AV + ++ + L G AT + A + Sbjct: 234 RVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQ 293 Query: 405 MRDIRAGINRNNNGAMDNV 423 M+ I +++ + +DN+ Sbjct: 294 MKSISDKVSKTYSMNIDNL 312
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 25.9 bits (57), Expect = 0.007 Identities = 13/41 (31%), Positives = 18/41 (43%), Gaps = 14/41 (34%) Query: 25 EFGWITLEDVPKKYR--------------DKVKQLVESGNI 51 E GWI ED + +R + +K+LVE G I Sbjct: 148 EKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLVERGVI 188
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 28.5 bits (63), Expect = 0.006 Identities = 15/63 (23%), Positives = 25/63 (39%), Gaps = 5/63 (7%) Query: 40 VSAPVKHVLDNNKKAMEALESAIVKISDD-----LKDNNFKWTESKNHRDRLQKVQDQHE 94 + APV +D + L + + +SD LKDN F + R + D Sbjct: 38 IDAPVTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNEN 97 Query: 95 IRI 97 +R+ Sbjct: 98 VRL 100
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 27.8 bits (62), Expect = 0.009 Identities = 11/54 (20%), Positives = 21/54 (38%), Gaps = 5/54 (9%) Query: 46 VARNAVEAVEQIAYDKDIK---GIEKLTEAKIAVRDELSKHNVYLSDK--QMEV 94 ++V V Q + D + G+ K A R + K ++ + +EV Sbjct: 486 RTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEV 539
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 27.5 bits (61), Expect = 0.008 Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 5/44 (11%) Query: 7 RMILMFDMPTDTAEE-----RKAYRKFRKFLLSEGFIMHQFSIY 45 R + FD+ T + E+ R+ Y +KF+L GF Q+S Y Sbjct: 5 RKAINFDLSTKSLEKYFKDTREPYSLIKKFMLENGFEHRQYSGY 48
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 159 bits (403), Expect = 1e-43 Identities = 90/437 (20%), Positives = 178/437 (40%), Gaps = 85/437 (19%) Query: 12 KIRNFSIIAHIDHGKSTLADRILEK---TETVSSREMQAQLLDSMDLERERGITIKLNAI 68 KI N ++AH+D GK+TL + +L + S + D+ LER+RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 ELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLA 128 + E ++IDTPGH+DF EV RSL+ +GAIL++ A G++AQT + Sbjct: 62 SFQW-----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 129 LDNDLEILPVINKIDLPAADPERVRHEVEDVIG--------------------------- 161 + + INKID D V ++++ + Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 162 --LDASEAVLASAKAGIGI--EEI--------------------------LEQIVEKV-- 189 ++ ++ +L +G + E+ ++ ++E + Sbjct: 177 TVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITN 236 Query: 190 --PAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVG 247 + T + L +F Y R + +R+ +G++ D +++ K +TE+ Sbjct: 237 KFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-KITEMY 295 Query: 248 IFTP-KAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFA 306 + D +G++ + + +GDT L E P++ Sbjct: 296 TSINGELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQRERIENPL------PLLQT 348 Query: 307 GIYPIESNKYNDLREALEKLQLNDASLQFE--PETSQALGFGFRCGFLGLLHMDVIQERL 364 + P + + L +AL ++ +D L++ T + + FLG + M+V L Sbjct: 349 TVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEII-----LSFLGKVQMEVTCALL 403 Query: 365 EREFNIDLIMTAPSVVY 381 + ++++++ + P+V+Y Sbjct: 404 QEKYHVEIEIKEPTVIY 420 Score = 43.7 bits (103), Expect = 2e-06 Identities = 21/104 (20%), Positives = 41/104 (39%), Gaps = 12/104 (11%) Query: 393 VSNPSEFPDPTRVAFIE----------EPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMD 442 VS P++F + + EPY+ +I PQE++ + + + V Sbjct: 510 VSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ 569 Query: 443 YIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYR 486 + +N V + +IP I ++ L T G + ++ Y Sbjct: 570 -LKNNEVILSGEIPARCI-QEYRSDLTFFTNGRSVCLTELKGYH 611
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 67.8 bits (165), Expect = 3e-14 Identities = 39/105 (37%), Positives = 49/105 (46%), Gaps = 9/105 (8%) Query: 324 LPGKPAPQTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKLQTQGGNQLAK 383 L K A Q E+ + +TP P N + G + G Sbjct: 444 LKEKLAKQAEELAKLRAGKASDSQTP---------DAKPGNKAVPGKGQAPQAGTKPNQN 494 Query: 384 TPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN 428 +T RQLP+TGET NPFFTAAA+ +M TAGV AV KR+E N Sbjct: 495 KAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN 539
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-17 Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Query: 3 KILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFKGYDLILLDIMMPNISGTE 62 IL DDD I ++ AL Y V + DL++ D++MP+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 FCYKIREE-VHSPIIFVSALDGDNEIVQALNIGGDDFIVKPFSLKQFVAKVNSHLKREER 121 +I++ P++ +SA + ++A G D++ KPF L + + + L +R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 AKIKNEAEER 131 K E + + Sbjct: 125 RPSKLEDDSQ 134
>NISIN#Nisin signature. Length = 57 Score = 26.3 bits (57), Expect = 0.002 Identities = 17/32 (53%), Positives = 23/32 (71%), Gaps = 2/32 (6%) Query: 4 TIKDFDLDL-KTNKKDT-ATPYVGSRYLCTPG 33 + KDF+LDL +KKD+ A+P + S LCTPG Sbjct: 2 STKDFNLDLVSVSKKDSGASPRITSISLCTPG 33
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 31.3 bits (70), Expect = 0.003 Identities = 17/47 (36%), Positives = 29/47 (61%), Gaps = 7/47 (14%) Query: 184 NKWYLFPYDWSLKLLEPMTRMRINSIPFGAEFVPDYSQIFISLFLGI 230 NK Y+ +W+ +P+T+ +IN+IP AEF+ + S I S +G+ Sbjct: 639 NKAYI---EWT----DPITKAKINTIPTSAEFIKNLSSIRRSSNVGV 678
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 36.6 bits (84), Expect = 1e-04 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 31 SGSQSDKLVIYNWGDYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVP 90 S S V+ N+ YI P LL++ + + + T+ SNE + TY +AV Sbjct: 21 SSCGSTTFVLANFESYISPLLLER--VQEKHPLTFLTYPSNEKLINGF--ANNTYSVAVA 76 Query: 91 SDYTIDKMIKENLLNKLDKSKL 112 S Y + ++I+ +LL+ +D S+ Sbjct: 77 STYAVSELIERDLLSPIDWSQF 98
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.2 bits (164), Expect = 3e-15 Identities = 23/131 (17%), Positives = 50/131 (38%), Gaps = 2/131 (1%) Query: 3 VLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTDYAIDLILLDIHITDGNGI 62 +L+ +DD + + L + + + + + + DL++ D+ + D N Sbjct: 6 ILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 QFLEKWRAQHIPCEVIIISAANDGNIIRDGFHLGIIDYLIKPFTFERFQESIQQFVTHRE 122 L + + V+++SA N G DYL KPF I + + + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 123 HLANQQLEQAQ 133 ++ + +Q Sbjct: 124 RRPSKLEDDSQ 134
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 32.0 bits (73), Expect = 0.002 Identities = 14/75 (18%), Positives = 27/75 (36%), Gaps = 8/75 (10%) Query: 172 TIGILERIVIGVCMIMG---QFASIGLVFTAKSIA-RYNKISESPAFAEYYLIGSLF--- 224 L ++ V +M G + + ++I KI+ + I SL Sbjct: 82 EFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKINPIEGAKRIFSIKSLVEFL 141 Query: 225 -SILSVFIAAWICFF 238 SIL V + + + + Sbjct: 142 KSILKVVLLSILIWI 156
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.025 Identities = 8/28 (28%), Positives = 14/28 (50%) Query: 87 EILAPADGLVSKIHVVANQTVESEQVLI 114 EI + +V +I V ++V VL+ Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLL 125 Score = 26.3 bits (58), Expect = 0.031 Identities = 13/40 (32%), Positives = 22/40 (55%) Query: 51 VKAPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILA 90 +K + V I EG++V+KG+ +L L A+ E + L Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.004 Identities = 10/49 (20%), Positives = 22/49 (44%) Query: 65 AIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEIVASSAGTITA 113 I + +++V G+ V + LL L A+ E + + + + + A Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQA 146 Score = 26.7 bits (59), Expect = 0.030 Identities = 9/30 (30%), Positives = 14/30 (46%) Query: 102 EIVASSAGTITAIHVGQGQVVNPGDGLITI 131 EI + I V +G+ V GD L+ + Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKL 127
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 65.8 bits (160), Expect = 5e-14 Identities = 76/299 (25%), Positives = 120/299 (40%), Gaps = 45/299 (15%) Query: 36 DLKVAMVTDTGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAV 95 LK ++TD G +DDKSFNQSA+E L++ + K TG + S + + ++A+ Sbjct: 61 KLKPVLITDEGKIDDKSFNQSAFEALKA------INKQTGIEINNVEPSSNFESAYNSAL 114 Query: 96 SGGYQLIYGIGFALKDAIAKAAGD------NEGVKFVIIDDIIEGKDNV-ASVTFADHEA 148 S G+++ GF + +I + +K + ID IE + S+ F E+ Sbjct: 115 SAGHKIWVLNGFKHQQSIKQYIDAHREELERNQIKIIGIDFDIETEYKWFYSLQFNIKES 174 Query: 149 AYLAGIAAAKTTKTK-----TVGFVGGMEGTVITRFEKGFEAGVKS---------VDDTI 194 A+ G A A + V GG +T F +GF G+ + T Sbjct: 175 AFTTGYAIASWLSEQDESKRVVASFGGGAFPGVTTFNEGFAKGILYYNQKHKSSKIYHTS 234 Query: 195 QVKVDYAGSFGDAAKGKTIAAAQYAAGADVIYQAAGG---TGAGVFNEAKAINEKRSEAD 251 VK+D +G I + ADV Y G F + N+ + Sbjct: 235 PVKLD-SGFTAGEKMNTVINNVLSSTPADVKYNPHVILSVAGPATFETVRLANKGQ---- 289 Query: 252 KVWVIGVDRDQKDEGKYTSKDGKEANFVLASSIKEVGKAVQLINKQVADKKFPGGKTTV 310 +VIGVD DQ +D +L S +K + +AV + +K G K V Sbjct: 290 --YVIGVDSDQG-----MIQDKDR---ILTSVLKHIKQAVYETLLDLILEKEEGYKPYV 338
>PF06580#Sensor histidine kinase Length = 349 Score = 39.1 bits (91), Expect = 2e-05 Identities = 15/75 (20%), Positives = 31/75 (41%), Gaps = 5/75 (6%) Query: 312 YGKIFYFQNQVNRSLRMDKALLKQLITILFDNAIKY----TDKNGIIEIIVKTTDKNLLI 367 + F+NQ+N ++ D + L+ L +N IK+ + G I + + + + Sbjct: 236 FEDRLQFENQINPAIM-DVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTL 294 Query: 368 SVIDNGPGITDEEKK 382 V + G K+ Sbjct: 295 EVENTGSLALKNTKE 309
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.5 bits (76), Expect = 7e-04 Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Query: 36 KGELVVIL-GASGAGKSTVLNILGGMD-TVDAGQVIIDGKD 74 K + V+L G G GKST++N L G+D D I GKD Sbjct: 594 KFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 41.2 bits (96), Expect = 6e-07 Identities = 13/48 (27%), Positives = 25/48 (52%) Query: 4 RHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTFYLHYTDK 51 ET+ ++ L ++Q + ++ ++ K AG+ RG Y H+ DK Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDK 55
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.3 bits (73), Expect = 0.002 Identities = 13/42 (30%), Positives = 22/42 (52%) Query: 64 TKYAVAESVQKVEELSLAQKEIEQNAEQAKVTAEAAEKQAKS 105 T+ + VE+ A+ E E+ E KVT++ + KQ +S Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQS 1136
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 548 bits (1414), Expect = 0.0 Identities = 269/371 (72%), Positives = 297/371 (80%), Gaps = 37/371 (9%) Query: 1 MTETIPLRVQFKRMKAAEWASSDVVLLEGEIGFETDTGFAKFGDGQNTFSKLKYLTGPKG 60 MTETIPLRVQFKRM A EW SDV+LLE EIGFETDTG+AKFGDG+N FSKLKYL Sbjct: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYL----- 55 Query: 61 PKGDTGIQGKTGGTGPRGPAGKPGTTDYDQLQNKPDLGAFAQKEETNSKITKLESSKADK 120 NKPDLGAFAQKEETNSKITKLESSKADK Sbjct: 56 --------------------------------NKPDLGAFAQKEETNSKITKLESSKADK 83 Query: 121 SAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAAMV 180 +AVY KAESKIELDKKL+L GG++TGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGA +V Sbjct: 84 NAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAGVV 143 Query: 181 MYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGKTNAVNIVMRQPSAPNFSSALNITSAN 240 +Y+N DT+DGPLM LR+ K+TF+QSA FVDYSGKTNAVNI MRQP+ PNFSSALNITS N Sbjct: 144 VYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNAVNIAMRQPTTPNFSSALNITSGN 203 Query: 241 EGGSAMQIRGVEKALGTLKITHENPNVEAKYDENAAALSIDIVKKQKGGKGTAAQGIYIN 300 E GSAMQIRGVEKALGTLKITHENPNVEA YDENAAALSIDIVKKQKGGKGTAAQGIYIN Sbjct: 204 ENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAALSIDIVKKQKGGKGTAAQGIYIN 263 Query: 301 STSGTAGKMLRIRNKNEDKFYVGPDGGFHSGANSTVAGNLTVNYPTSEKHAATKKYVDEK 360 STSGT GK+LRIRN +DKFYV DGGF++ S + GNL + PT++ HAATK YVD + Sbjct: 264 STSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQIDGNLKLKNPTADDHAATKAYVDSE 323 Query: 361 IAELKKLILKK 371 + +LK L++ K Sbjct: 324 VKKLKALLMDK 334
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 39.6 bits (92), Expect = 5e-05 Identities = 25/133 (18%), Positives = 59/133 (44%), Gaps = 7/133 (5%) Query: 501 LGASGQGLSSMLSSAWGNIQTVVSTAKNMITLAIDGIKL--VFSNLGNAGNILKGLLSAA 558 G G + + G ++ST +N + A+ +K+ + + GN+ L+ A Sbjct: 124 AGNILGGGAENIGDNLGKAGGILSTFQNFLGTALSSMKIDELIKKQKSGGNVSSSELAKA 183 Query: 559 WSAMQNAVVIAKGIINSAISAIKTAFSSFGNLVSSVSGTIKSVIGSLKNAFYSLASIDLV 618 + N +V +N+ +++ ++ G+++S+ + + N +L ++D + Sbjct: 184 SIELINQLVDTVASLNNNVNSFSQQLNTLGSVLSNTKH-----LNGVGNKLQNLPNLDNI 238 Query: 619 GAGRAIMQGFLNG 631 GAG + G L+ Sbjct: 239 GAGLDTVSGILSA 251
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.032 Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 139 KSEETEDYITDYVEGLVAAGLGAYQEDNLHMKVKLRS 175 K E +D YVE A Y E+N ++K+RS Sbjct: 48 KQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRS 84
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 151 bits (383), Expect = 1e-49 Identities = 49/154 (31%), Positives = 85/154 (55%), Gaps = 4/154 (2%) Query: 19 KKEASKNEKT--KAVLNQAVADLSVAASIVHQVHWYMRGPGFLYLHPKMDELLDSLNANL 76 K E +K +T + LN +++ + S +H+ HWY++GP F LH K +EL D + Sbjct: 2 KTENAKTNQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETV 61 Query: 77 DEMSERLITIGGAPYSTLAEFSKHSKLDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGL 136 D ++ERL+ IGG P +T+ E+++H+ + + + + ++ + LV Y +SS + + Sbjct: 62 DTIAERLLAIGGQPVATVKEYTEHASITDGGN--ETSASEMVQALVNDYKQISSESKFVI 119 Query: 137 DITDEEGDAGTNDLFTAAKTEAEKTIWMLQAERG 170 + +E D T DLF E EK +WML + G Sbjct: 120 GLAEENQDNATADLFVGLIEEVEKQVWMLSSYLG 153
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 33.4 bits (76), Expect = 7e-04 Identities = 9/34 (26%), Positives = 19/34 (55%) Query: 8 KLILQGGKAMVTIKQVAEEAGVSRSTVSRYISQK 41 +L Q G + ++ ++A+ AGV+R + + K Sbjct: 22 RLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDK 55
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 153 bits (388), Expect = 2e-50 Identities = 58/157 (36%), Positives = 94/157 (59%), Gaps = 2/157 (1%) Query: 5 IGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKKSYFKLEVRKAMLTQALADFT 64 +Y GSFDP+T GHLDI++R LFDQ+YV + NP K+ F ++ R + +A+A Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 65 NVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEENLEYFNHLLAPNIETVYLISRN 124 N V + E L ++ A++ + ++RGLR +DFE E + N LA ++ETV+L + Sbjct: 62 NAQVDSF-EGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTST 120 Query: 125 KWQALSSSRVRELIHFQSSLEGLVPQSVIAQV-EKMN 160 ++ LSSS V+E+ F ++E VP V A + ++ + Sbjct: 121 EYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFH 157
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 407 bits (1047), Expect = e-146 Identities = 141/315 (44%), Positives = 204/315 (64%), Gaps = 6/315 (1%) Query: 3 KQKIVVALGGNAIL--STDASAKAQQEALMSTSKSLVKLIKEGHEVIVTHGNGPQVGNLL 60 +++V+ALGGNA+ S + + + T++ + ++I G+EV++THGNGPQVG+LL Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61 Query: 61 LQQAAADSEKN-PAMPLDTCVAMTEGSIGFWLVNALDNELQAQGIQKEVAAVVTQVIVDA 119 L A + PA P+D AM++G IG+ + AL NEL+ +G++K+V ++TQ IVD Sbjct: 62 LHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDK 121 Query: 120 KDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWRKVVPSPKPVGIKEANVIRS 179 DPAF+NPTKP+GPF EE AK+ E G KED+GRGWR+VVPSP P G EA I+ Sbjct: 122 NDPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKK 181 Query: 180 LVDSGVVVVSAGGGGVPVVEDATSKTLTGVEAVIDKDFASQTLSELVDADLFIVLTGVDN 239 LV+ GV+V+++GGGGVPV+ + + GVEAVIDKD A + L+E V+AD+F++LT V+ Sbjct: 182 LVERGVIVIASGGGGVPVILED--GEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNG 239 Query: 240 VYVNFNKPDQTKLEEVTVSQMKEYITQDQFAPGSMLPKVEAAIAFVENKPNAKAIITSLE 299 + + + L EV V ++++Y + F GSM PKV AAI F+E +AII LE Sbjct: 240 AALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEW-GGERAIIAHLE 298 Query: 300 NIDNVLSANAGTQII 314 L GTQ++ Sbjct: 299 KAVEALEGKTGTQVL 313
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.7 bits (85), Expect = 4e-04 Identities = 11/74 (14%), Positives = 27/74 (36%), Gaps = 6/74 (8%) Query: 805 YLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVIQKEKDKQADYQ 864 + +L E + EL ++ +L+ + ++ +AK E + + + Sbjct: 248 AIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEI------LSAKEEYQLVTQLFKNEIL 301 Query: 865 AKYDATQERIAEMQ 878 K T + I + Sbjct: 302 DKLRQTTDNIGLLT 315
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.9 bits (210), Expect = 1e-19 Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 6/133 (4%) Query: 4 KVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPGMT 63 +L+ DD+ I L + G++V + ++ D++++DV MP Sbjct: 5 TILVADDDAAIRTVLNQAL--SRAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 64 GLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQAKMKQFKDC 123 DL+ K P L L++S F KA E YL KP D L + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFD---LTELIGIIGRA 118 Query: 124 LDAQQAESIRQEA 136 L + + E Sbjct: 119 LAEPKRRPSKLED 131
>PF06580#Sensor histidine kinase Length = 349 Score = 179 bits (456), Expect = 2e-53 Identities = 71/324 (21%), Positives = 132/324 (40%), Gaps = 34/324 (10%) Query: 251 LSKAYRMQYNRSGDLLAYVAVRKSYLLAEAVRTVFVYGLVSLLLAWLLLQLL-FRVFRNY 309 L+ AYR R G L + + A + + V+ W LL + + Sbjct: 55 LTHAYRSFIKRQG-WLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFT 113 Query: 310 IQQVSEITDTVEMVAAGDLSLTIDNSHMELELYHISEAINQMLASIKAYIDEVYVLEVEQ 369 + I V +V + M LY + +A ID+ + Sbjct: 114 LPLALSIIFNVVVV-----------TFMWSLLYF---GWHFFKNYKQAEIDQWK-MASMA 158 Query: 370 RDAQMRALQSQINPHFLYNTLEYIRMYALSCQQEELADVIYAFASLLRNNI--SQDKMTT 427 ++AQ+ AL++QINPHF++N L IR L + +++ + + L+R ++ S + + Sbjct: 159 QEAQLMALKAQINPHFMFNALNNIRALILE-DPTKAREMLTSLSELMRYSLRYSNARQVS 217 Query: 428 LKEELAFCEKYIYLYQMRYPDSFAYHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRH 487 L +EL + Y+ L +++ D + +I+ +I D+ +P ++Q LVEN HGI Sbjct: 218 LADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQ 277 Query: 488 DNALSIKALDETDHFLIQVLDNGRGISQERLADMERRLQEHQTTGNSSIGLQNVYLRLFH 547 + +K + ++V + G L T ++ GLQNV RL Sbjct: 278 GGKILLKGTKDNGTVTLEVENTG-------------SLALKNTKESTGTGLQNVRERLQM 324 Query: 548 HFRDRVSWSMAKEPNGGFIIQIRI 571 + ++++ G + I Sbjct: 325 LYGTEAQIKLSEKQ-GKVNAMVLI 347
>PF05043#Transcriptional activator Length = 493 Score = 54.6 bits (131), Expect = 5e-10 Identities = 30/162 (18%), Positives = 71/162 (43%), Gaps = 7/162 (4%) Query: 23 IEDLMDKERRAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTLLKYIDNLNHLCREQGLAC 82 + DL+ K+ Q LL L+ K +L L N ++ + + ++ + Sbjct: 1 MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIF-- 58 Query: 83 QLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMYCHEHFNITNLSVELMVSEAT 142 + + E + K S + IL +++ +E ++ E +S ++ Sbjct: 59 -HSSTNGIRIINTDDS-DIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSS 116 Query: 143 LNRQLAHLNQLLS---EFDLALSQGRQLGSELQWRYFYFELF 181 L R ++ +N+++ +F+++L+ + +G+E RYF+ + F Sbjct: 117 LYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYF 158
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 40.0 bits (93), Expect = 1e-06 Identities = 15/78 (19%), Positives = 29/78 (37%), Gaps = 3/78 (3%) Query: 69 NQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEFQNKDQE 128 + S ++ +D A + + + E L + D E + YE+ + Sbjct: 134 TEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTRLVIYPDEETPRLAYEVNVRFLTPV 193 Query: 129 ---YSYTIDANSGDIVEK 143 + Y IDA G ++ K Sbjct: 194 PGNWIYMIDAADGKVLNK 211
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 63.8 bits (155), Expect = 2e-15 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 4/86 (4%) Query: 62 CLLARLDEKVVGLLNLSGEVLSQGQVEADVFMLVAKTYRGYGIGQLLLEIALDWAEENPY 121 L L+ +G + + +E + VAK YR G+G LL A++WA+EN + Sbjct: 67 AFLYYLENNCIGRIKIRSNWNGYALIED---IAVAKDYRKKGVGTALLHKAIEWAKENHF 123 Query: 122 IESLKLDVQVRNTKAIYLYKKYGFRI 147 L L+ Q N A + Y K+ F I Sbjct: 124 C-GLMLETQDINISACHFYAKHHFII 148
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 31.7 bits (72), Expect = 0.006 Identities = 19/123 (15%), Positives = 43/123 (34%), Gaps = 8/123 (6%) Query: 372 LTAVSTAVCFLLSILLLPLVGIVPAAATAPALIVVGVMMVSSFLDVNWSKF--ADALPAF 429 L+ V V L PL+ + A A ++ G ++ + + K + Sbjct: 72 LSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKINPIEGAKRI 131 Query: 430 FAA-FFMALCCSISYGIAAAFIFYCLVK-----VVEGKTKDIHPIIWGATFLFIVNFIIL 483 F+ + SI + + + + ++K +++ T I I + +I Sbjct: 132 FSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVIC 191 Query: 484 TIL 486 T+ Sbjct: 192 TVG 194
>INTIMIN#Intimin signature. Length = 939 Score = 30.0 bits (67), Expect = 0.011 Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 15/90 (16%) Query: 171 NLSNIPLLILD-----DLGIERDTSYAREQVYNI-------INSRYLKGRPTIFTTNLSL 218 N + IPL+ + G E D Y+ + Y I +Y+ T+ + L Sbjct: 378 NYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDL 437 Query: 219 EIIQNPNIDLEYQRIYSRILEMTIPVKVTG 248 + +N NI LEY++ IL + IP + G Sbjct: 438 -VQRNNNIILEYKK--QDILSLNIPHDING 464
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.7 bits (74), Expect = 0.007 Identities = 32/301 (10%), Positives = 77/301 (25%), Gaps = 16/301 (5%) Query: 63 AKDQKQDKLKDFQKAKNKERIRKEVLDNKNKAEETKQTNLEIRTDESYKLDEELDVDIKK 122 A + D L+ Q+ +K I L KN L+ DE + ++K Sbjct: 44 ATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRK 103 Query: 123 VNFDSENSRNINSNKLTTDDISAKAQPISNKKSSSKRQVLKNYENKFIHSKDKFQDKINE 182 + + KA + + K + Sbjct: 104 NDKSLSEKASKIQELEARKADLEKALEGAMNF---STADSAKIKTLEAEKAALAARKADL 160 Query: 183 RESKRIHTSEDKPIEAKKSKRIYRKDKLVKDEVSKNESNANIDKKQKQKLYQEKRFRDKE 242 ++ + AK + + E + E ++ + + E Sbjct: 161 EKALEGAMNFSTADSAKIKTL---EAEKAALEARQAELEKALEGAMNFSTADSAKIKTLE 217 Query: 243 KISKEIDKESKLSEVDTDKTFDNPEFKDNNLEFIKDEKETSLKPSEQKKVNKKKTYYKR- 301 + E + + ++ + E E + + Q ++ K Sbjct: 218 AEKAALAARKADLEKALEGAMN--FSTADSAKIKTLEAEKAALEARQAELEKALEGAMNF 275 Query: 302 ---KNYESDKFTRKKIDDLKNESKKVSTKD----SKKAQDVKDFISDKKIGELEKSKSKL 354 + + +K ++ ++++ S + +LE KL Sbjct: 276 STADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKL 335 Query: 355 K 355 + Sbjct: 336 E 336
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 76.3 bits (187), Expect = 1e-16 Identities = 54/312 (17%), Positives = 116/312 (37%), Gaps = 20/312 (6%) Query: 292 DEKDNKIDDLTKNIKDLENQIKDLNDKKQEDQSKIDELKEKLESCKDNGEKLKQEKAKLE 351 + D + + I++LE + DL + + K+++ + L KA LE Sbjct: 102 RKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLE 161 Query: 352 EEIRNKDNKIAQLNKEIEDLKNSNNDELIAEITQLKDELKRLQDENEKLKEDYSSTKWEL 411 + + N + +I+ L+ L A +L+ L+ + + + + E Sbjct: 162 KALEGAMNFSTADSAKIKTLEAEKA-ALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 220 Query: 412 EAEKEKTDKNENKIKEMQEKLESLEGELAKKTKEIGDKDNRIKDLEKALDEKDTKIKDLE 471 A + E ++ + ++ E + R +LEKAL+ Sbjct: 221 AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 280 Query: 472 SKKKETENSKSECFKKIEELQKAIDSLKESSENTKKELEEKIKGLEEKQKSSEEEIKKLK 531 +K K E K +E + ++ + ++ L + E +K E E +KL+ Sbjct: 281 AKIKTLEAEK----AALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLE 336 Query: 532 EELD-------------KKIEEAKKLIEEANKKAKEELEKQTKDDKDKNLNQDLSKKLDE 578 E+ EAKK +E ++K +E + + + ++L +DL + Sbjct: 337 EQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEE--QNKISEASRQSLRRDLDASREA 394 Query: 579 LLKLQKENKEKK 590 +++K +E Sbjct: 395 KKQVEKALEEAN 406 Score = 70.9 bits (173), Expect = 1e-14 Identities = 40/300 (13%), Positives = 111/300 (37%), Gaps = 9/300 (3%) Query: 319 KQEDQSKIDELKEKLESCKDNGEKLKQEKAKLEEEIRNKDNKIAQLNKEIEDLKNSNNDE 378 + +++++E+ + + LK + + L + + +L +E+ + K Sbjct: 45 TRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKN 104 Query: 379 ---------LIAEITQLKDELKRLQDENEKLKEDYSSTKWELEAEKEKTDKNENKIKEMQ 429 I E+ K +L++ + S+ LEAEK + +++ Sbjct: 105 DKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKAL 164 Query: 430 EKLESLEGELAKKTKEIGDKDNRIKDLEKALDEKDTKIKDLESKKKETENSKSECFKKIE 489 E + + K K + + ++ + L++ + + + + Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224 Query: 490 ELQKAIDSLKESSENTKKELEEKIKGLEEKQKSSEEEIKKLKEELDKKIEEAKKLIEEAN 549 + ++ E + N KIK LE ++ + E +L++ L+ + + + Sbjct: 225 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIK 284 Query: 550 KKAKEELEKQTKDDKDKNLNQDLSKKLDELLKLQKENKEKKEDKKSQDKKWDELLKADDK 609 E+ + + ++ +Q L+ L + ++E K+ +++ +K +E K + Sbjct: 285 TLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEA 344 Score = 62.0 bits (150), Expect = 6e-12 Identities = 60/308 (19%), Positives = 121/308 (39%), Gaps = 7/308 (2%) Query: 289 QDIDEKDNKIDDLTKNIKDLENQIKDLNDKKQEDQSKIDELKEKLESCKDNGEKLKQEKA 348 KI L L + DL + + K+++ + L+ +A Sbjct: 204 NFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQA 263 Query: 349 KLEEEIRNKDNKIAQLNKEIEDLKNSNNDELIAEITQLKDELKRLQDENEKLKEDYSSTK 408 +LE+ + N + +I+ L+ + L AE L+ + + L + L+ D +++ Sbjct: 264 ELEKALEGAMNFSTADSAKIKTLE-AEKAALEAEKADLEHQSQVLNANRQSLRRDLDASR 322 Query: 409 WELEAEKEKTDKNENKIKEMQEKLESLEGELAKKTKEIGDKDNRIKDLEKALDEKDTKIK 468 + + + K E + K + +SL +L + + + LE+ + + Sbjct: 323 EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQ 382 Query: 469 DLESKKKETENSKSECFKKIEELQKAIDSLKESSENTKKELEEKIKGLEEKQKSSEEEIK 528 L + +K + K +EE + +L++ ++ ++ + K E Q E E K Sbjct: 383 SLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAK 442 Query: 529 KLKEELDKKIEEAKKLIEEANKKAKEELEKQTKDDKDKNLNQDLSKKLDELLKLQKENKE 588 LKE+L K+ EE KL +A + + QT D K N + + +NK Sbjct: 443 ALKEKLAKQAEELAKL------RAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKA 496 Query: 589 KKEDKKSQ 596 ++ K Q Sbjct: 497 PMKETKRQ 504 Score = 52.0 bits (124), Expect = 7e-09 Identities = 31/235 (13%), Positives = 74/235 (31%), Gaps = 11/235 (4%) Query: 410 ELEAEKEKTDKNENKIKEMQEKLESLEGELAKKTKEIGDKDNRIKDLEKALDEKDTKIKD 469 LE +E+ DK E + ++ K L + + + ++ L + D + + Sbjct: 51 TLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSE 110 Query: 470 LESKKKETENSKSECFKKIEELQKAIDSLKESSENTKKELEEKIKGLEEKQKSSEEEIKK 529 SK +E E K++ K +E + + LE + L ++ E+ ++ Sbjct: 111 KASKIQELEARKADLEKALEGAMNFSTADSAKIKT----LEAEKAALAARKADLEKALEG 166 Query: 530 LKEELD------KKIEEAKKLIEEANKKAKEELEKQTKDDKD-KNLNQDLSKKLDELLKL 582 K +E K +E + ++ LE + L + L Sbjct: 167 AMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAAR 226 Query: 583 QKENKEKKEDKKSQDKKWDELLKADDKNILNQFDLNKMKKQEEQQNKKQVKDEKE 637 + + ++ E + +K + ++ + + Sbjct: 227 KADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.6 bits (149), Expect = 7e-14 Identities = 31/183 (16%), Positives = 68/183 (37%), Gaps = 8/183 (4%) Query: 15 EKQKQIINAAIKEFVRNGFEKASTNEIVKRANISKGSLFNYFNSKKDLYLYLIE-YSSKA 73 E ++ I++ A++ F + G S EI K A +++G+++ +F K DL+ + E S Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 74 IVNLNEEIDLSETDLFKRIERVALQKFYVQQKYPQAFEFLASTKQE-ESVEVKDIIKQRL 132 E D + + + + + + E V +++Q Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 133 NPIYNQAINK----LYKDIDYSKFREGVDIEKAIEILNWTMFGVGEKGL--KELFTFDDI 186 + ++ ++ L I+ + +A I+ + G+ E L + F Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKE 190 Query: 187 GRF 189 R Sbjct: 191 ARD 193
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 26.4 bits (58), Expect = 0.035 Identities = 13/70 (18%), Positives = 25/70 (35%), Gaps = 9/70 (12%) Query: 3 ITKIH-PIKSTLNLAIDYITNSEKTDEKVLVSTFKCHPSTAHIQFLKTREDNDTKGTVLA 61 I K++ P K + L I + K+L+S + I + N K + Sbjct: 24 IDKVNQPEKDEIILNI----RKGRLSFKLLIS---SSSNYPRIHLTDLTKPNPIKAPMFC 76 Query: 62 RHLIQSFLPG 71 L + ++ Sbjct: 77 MVL-RKYISN 85
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.8 bits (69), Expect = 0.013 Identities = 19/93 (20%), Positives = 41/93 (44%) Query: 376 KNSRAGSLEEQVFEAIKEKYGLEDPIKDEKVKVKPMEKSIEDLEAKKMQSFEKYKLGKMN 435 + +LE + E K G + + K+K +E LEA+K + ++ N Sbjct: 251 LEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNAN 310 Query: 436 RQKFIDLKNSIDEELQAIKEKIQKAKEEKEVID 468 RQ ++ E + ++ + QK +E+ ++ + Sbjct: 311 RQSLRRDLDASREAKKQLEAEHQKLEEQNKISE 343
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.0 bits (109), Expect = 3e-08 Identities = 21/118 (17%), Positives = 51/118 (43%), Gaps = 6/118 (5%) Query: 2 KILLIDDHRLFAKSIQLLFQQYD-EVDVIDTITSHFNDVTIDLSKYDIILLDINLTNISK 60 IL+ DD + + +V + + + + D+++ D+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI--AAGDGDLVVTDVVM---PD 59 Query: 61 ENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGFVDKNIDPKQLISILKK 118 EN ++ + ++ P L V++++ + +A + GAY ++ K D +LI I+ + Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 29.8 bits (67), Expect = 0.005 Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 11/85 (12%) Query: 1 MKKKERHEKILDILKVDGFIKVKDIIDEM-----NISDMTARRDLDTLADKGLL-IRTHG 54 M K +RH KI +I+ + +++D + N++ T RD+ L L+ + T+ Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKEL---HLVKVPTNN 57 Query: 55 GAQYLDYSSAKDEGHEKTHTEKKVL 79 G+ YS D+ K+ L Sbjct: 58 GSYK--YSLPADQRFNPLSKLKRSL 80
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 29.8 bits (67), Expect = 0.009 Identities = 8/44 (18%), Positives = 17/44 (38%), Gaps = 2/44 (4%) Query: 227 INGYKVTSWNDLTEAV-DLATRD-LGPSQTIKVTYKSHQRLKTV 268 + ++ L E + DL +D + +Q+LK + Sbjct: 80 FDITEIGEQYSLKETIQDLCAKDFHQKLKEFTEKTPKNQKLKDL 123
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 34.7 bits (79), Expect = 0.003 Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 5/96 (5%) Query: 1066 QAGVTAIAKPKGVQFTKEGLTIDSLTALVLKVSSKPADPSQKKSQTGNHQTKTPDGSKDL 1125 QA + A AK + K+ + L A S P K+ G Q + Sbjct: 434 QAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQ 493 Query: 1126 DKSLMTRPKRAQTNQKLPKTGEASSKGLLAAGVALL 1161 +K+ M KR +LP TGE ++ AA + ++ Sbjct: 494 NKAPMKETKR-----QLPSTGETANPFFTAAALTVM 524
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.4 bits (73), Expect = 0.003 Identities = 14/56 (25%), Positives = 20/56 (35%), Gaps = 9/56 (16%) Query: 34 IVFVGPSGCGKSTTLPMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALY 89 +V G G GKST + + GL+ S+ IG +D Y Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG---------TGKDSYEQIAGIVAY 645
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 7e-04 Identities = 10/30 (33%), Positives = 19/30 (63%) Query: 243 ALWSEHGNLVQTAQRLYIHRNSLQYKLDKF 272 AL + GN ++ A L ++RN+L+ K+ + Sbjct: 444 ALTATRGNQIKAADLLGLNRNTLRKKIREL 473
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 789 bits (2039), Expect = 0.0 Identities = 374/440 (85%), Positives = 398/440 (90%) Query: 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLDRPSVNNIQLVVSVAGTVEGTNQEIS 60 MKNYLSFGMFALLFALTFGTV VQAIAGPEWLLDRPSVNN QLVVSVAGTVEGTNQ+IS Sbjct: 1 MKNYLSFGMFALLFALTFGTVNSVQAIAGPEWLLDRPSVNNSQLVVSVAGTVEGTNQDIS 60 Query: 61 LKFFEIDLTSGPAQGGKTEQGLSPKSKPFATNKGAMPHKLEKADLLKAIQEQLIANVHSN 120 LKFFEIDLTS PA GGKTEQGLSPKSKPFAT+ GAM HKLEKADLLKAIQEQLIANVHSN Sbjct: 61 LKFFEIDLTSRPAHGGKTEQGLSPKSKPFATDSGAMSHKLEKADLLKAIQEQLIANVHSN 120 Query: 121 DGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYQPKAVHNS 180 D YFEVIDFASDATITDRNGKVYFAD+D SVTLPTQPVQEFLLSGHVRVRPY+ K + N Sbjct: 121 DDYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLSGHVRVRPYKEKPIQNQ 180 Query: 181 AERVNVNYEVSFVSETGDLDFTPLLRNQYQLTTLAVGDSLSSQELAAIAQFILSKKYPDY 240 A+ V+V Y V F D DF P L++ L TLA+GD+++SQEL A AQ IL+K +P Y Sbjct: 181 AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKNHPGY 240 Query: 241 IITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIVEKTNNTDLISEKY 300 I +RDSSIVTHDNDIFRTILPMDQEFTY +K+REQAY+ N K+G+ E+ NNTDLISEKY Sbjct: 241 TIYERDSSIVTHDNDIFRTILPMDQEFTYRVKNREQAYRINKKSGLNEEINNTDLISEKY 300 Query: 301 YVLKKGEKPYDPFDRSHLKLFTINYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK 360 YVLKKGEKPYDPFDRSHLKLFTI YVDV+TNELLKSEQLLTASERNLDFRDLYDPRDKAK Sbjct: 301 YVLKKGEKPYDPFDRSHLKLFTIKYVDVDTNELLKSEQLLTASERNLDFRDLYDPRDKAK 360 Query: 361 LLYNNLDAFGIMDYTLTGKVEDNHNDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEER 420 LLYNNLDAFGIMDYTLTGKVEDNH+DTNRIITVYMGKRPEGENASYHLAYDKDRYTEEER Sbjct: 361 LLYNNLDAFGIMDYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEER 420 Query: 421 EVYSYLRYTGTPIPDNPNDK 440 EVYSYLRYTGTPIPDNPNDK Sbjct: 421 EVYSYLRYTGTPIPDNPNDK 440
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 63.2 bits (153), Expect = 5e-13 Identities = 42/124 (33%), Positives = 53/124 (42%), Gaps = 3/124 (2%) Query: 272 EKAPEKSPEVTPTPETPEQP---GEKAPEKSPEVTPTPETPEQPGEKAPEKSKEVTPAPE 328 K E+S ++T + Q E K E + KA + Sbjct: 416 NKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGN 475 Query: 329 KPADKEANQTPERRNGNMAKTPVANNHRRLPATGEQANPFFTAAAVAVMTTAGVLAVTKR 388 K + N K P+ R+LP+TGE ANPFFTAAA+ VM TAGV AV KR Sbjct: 476 KAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKR 535 Query: 389 KENN 392 KE N Sbjct: 536 KEEN 539
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.7 bits (77), Expect = 0.001 Identities = 28/155 (18%), Positives = 46/155 (29%), Gaps = 38/155 (24%) Query: 8 RMRPKTISEVIGQKHLVGEGKIIRRMVE-----ANRLSSMILYGPPGIGKTSIASAIAGT 62 R K + LVG ++ + ++++ G G GK +A A+ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 63 TRYAFRTF--------------------------NATIDSKKRLQEIAEEAKFSGGLVLL 96 + F A S R ++ + G L Sbjct: 184 GKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQ-------AEGGTLF 236 Query: 97 LDEIHRLDKTKQDFLLPLLENGTIIMIGATTENPF 131 LDEI + Q LL +L+ G +G T Sbjct: 237 LDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRS 271
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 247 bits (633), Expect = 3e-83 Identities = 82/323 (25%), Positives = 143/323 (44%), Gaps = 34/323 (10%) Query: 1 MKKGFFLMAMAVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVR-MI 59 MKK L+ + +S +++ C Q + VV + + +TK ++GD D+ ++ Sbjct: 1 MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIV 60 Query: 60 QSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLE----AWARDLDPNLKKSKVDVFEASKP 115 G H +EP DV +ADL Y+ LE AW L N KK++ + A Sbjct: 61 PIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFA--- 117 Query: 116 LTLDRVKGLEDMEVTQGIDPATLY--------DPHTWTDPVLAGEEAVNIAKELGRLDPK 167 V+ G+D L DPH W + A NIAK+L DP Sbjct: 118 -------------VSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPN 164 Query: 168 HKDSYTKKAKAFKKEAEQLTEEYTQKFKKVR--SKTFVTQHTAFSYLAKRFGLKQLGISG 225 +K+ Y K K + + ++L +E KF K+ K VT AF Y +K +G+ I Sbjct: 165 NKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWE 224 Query: 226 ISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT---LSPLEA 282 I+ E+E +P Q+K + + +++ V ++F E +V+ + +++ T + + Sbjct: 225 INTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAE 284 Query: 283 APSGNKTYLENLRANLEVLYQQL 305 +Y ++ NL+ + + L Sbjct: 285 QGKEGDSYYSMMKYNLDKIAEGL 307
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 41.6 bits (97), Expect = 3e-06 Identities = 37/249 (14%), Positives = 76/249 (30%), Gaps = 27/249 (10%) Query: 37 AVDSIPPISLTQRTPATTSEKWHHIDDKGSIPLGISLEAAKKDFKEEVEKSRLSEEQKQT 96 VD P TP+ T+E ++ + ++ E + +E Q Sbjct: 1019 RVDEAPVPPPAPATPSETTET-------------VAENSKQESKTVEKNEQDATETTAQ- 1064 Query: 97 YNQKIDAETDKDELLSTYHRDYLTAVKNLPTSTEPVEASVQETQASVSDSMVTGDSTSVT 156 + A+ K + + + + + T+ E T + V + T Sbjct: 1065 --NREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQ-- 1120 Query: 157 ADSPKESPVAPASSPESEDSSVASSEETSSPETPVAPETPEEPAAPSPSPESEEPSVAAS 216 + V SP+ E S + + E +EP + + + E + Sbjct: 1121 ----EVPKVTSQVSPKQEQSETVQPQAEPARE-NDPTVNIKEPQSQTNTTADTEQPAKET 1175 Query: 217 SEETPTPSTPEEPA----APSPSPESEEPSVAASSEETPTPSTPEEPAAPSPSPESEDSS 272 S P T + +PE+ P+ + + + + P+ S + Sbjct: 1176 SSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE 1235 Query: 273 VAATTSPSP 281 A T+S Sbjct: 1236 PATTSSNDR 1244 Score = 35.4 bits (81), Expect = 2e-04 Identities = 36/195 (18%), Positives = 72/195 (36%), Gaps = 13/195 (6%) Query: 90 SEEQKQTYNQKIDAETDKDELLSTYHRDYLTAVKNLPTSTEPVEASVQE-TQASVSDSMV 148 S ++D +T T +N ++ VE + Q+ T+ + + V Sbjct: 1009 SVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREV 1068 Query: 149 TGDSTSVTADSPKESPVAPASSPESEDSSVASSEETSSPETPVAPETPEEPAAPSPSPES 208 ++ S + + + VA + S E++++ ++ET++ E EE A Sbjct: 1069 AKEAKSNVKANTQTNEVAQSGS-ETKETQTTETKETATVEK-------EEKAKVETEKTQ 1120 Query: 209 EEPSVAASSEETPTPSTPEEPAAPSPSPESEEPSVAASSEETPTPSTPEEPA----APSP 264 E P V + S +P A ++ +T T + E+PA + Sbjct: 1121 EVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVE 1180 Query: 265 SPESEDSSVAATTSP 279 P +E ++V S Sbjct: 1181 QPVTESTTVNTGNSV 1195 Score = 28.5 bits (63), Expect = 0.033 Identities = 15/75 (20%), Positives = 27/75 (36%), Gaps = 5/75 (6%) Query: 203 SPSPESEEPSVAASSEETPTPSTPEEPAAPSPSPESEEPSVAASSEETPTPSTPEEPAAP 262 +P E +V ++ TP + P+ PS + E +A E P P P+ Sbjct: 982 NPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEE-----IARVDEAPVPPPAPATPSET 1036 Query: 263 SPSPESEDSSVAATT 277 + + + T Sbjct: 1037 TETVAENSKQESKTV 1051
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 107 bits (269), Expect = 3e-27 Identities = 50/226 (22%), Positives = 85/226 (37%), Gaps = 47/226 (20%) Query: 118 KAGKGAGTVVAVIDAGFDKNHEAWRLTDKSKARYQSKEDLEKAKKDHGITYGEWVNDKVA 177 +G G VAV+D G D +H DL KA+ G + + Sbjct: 36 NQTRGRGVKVAVLDTGCDADHP----------------DL-KARIIGGRNFTDDDEGDPE 78 Query: 178 YYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLA 237 + DY+ HGTHV+G ++ + G PEA LL+++V G Sbjct: 79 IFKDYNG---------HGTHVAGTIAATENE-----NGVVGVAPEADLLIIKVLNKQGSG 124 Query: 238 DYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGND 297 Y Q I A+ +I+MS G E +A A + + ++ +AGN+ Sbjct: 125 QYD-WIIQGIYYAIEQKVDIISMSLGGPED-----VPELHEAVKKAVASQILVMCAAGNE 178 Query: 298 SSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETAT 343 +T +G P + ++V + + D+ +E + Sbjct: 179 GDGDDRT----------DELGYPGCYNEVISVGAINFDRHASEFSN 214 Score = 79.9 bits (197), Expect = 5e-18 Identities = 37/139 (26%), Positives = 58/139 (41%), Gaps = 22/139 (15%) Query: 458 NATPKVLPTASGTK---LSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSM 514 +V+ + S FS+ + D+ APG+DILS+V KYA SGTSM Sbjct: 192 GCYNEVISVGAINFDRHASEFSNSNN------EVDLVAPGEDILSTVPGGKYATFSGTSM 245 Query: 515 SAPLVAGIMGL-LQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGA 573 + P VAG + L Q + D+T E L+ L + SP+ +G Sbjct: 246 ATPHVAGALALIKQLANASFERDLTEPE----LYAQLIKRTIPLGN-------SPKMEGN 294 Query: 574 GAVDAKKASA-ATMYVTDK 591 G + + ++ T + Sbjct: 295 GLLYLTAVEELSRIFDTQR 313
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 117 bits (293), Expect = 2e-31 Identities = 151/314 (48%), Positives = 202/314 (64%), Gaps = 20/314 (6%) Query: 28 KAKYDALRDENTGLRGDRTKLLKKLEEEQEKSKNLEKQKQELENQALNFHDVIETQEKEK 87 + + + +T L + + + LEK + N + I+T E EK Sbjct: 231 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 290 Query: 88 EDLKTTLAKTTKENEISEASRKGLSSDLEASRAAKKELEAKHQKLEAENKKLTEANQVSE 147 L+ A ++++ A+R+ L DL+ASR AKK+LEA+HQKLE E N++SE Sbjct: 291 AALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLE-------EQNKISE 343 Query: 148 ASRKGLSNDLEASRAAKKELEAKHQKLEADYQVSETSRKGLSRDLEASREANKKVTSELT 207 ASR+ L DL+ASR AKK+LEA+HQKLE ++SE SR+ L RDL+ASREA K+V L Sbjct: 344 ASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALE 403 Query: 208 QAKAQLSALE-------ESKKLSEKEKAELQAKLDAQGKALKEQLAKQTEELAKLRAEKA 260 +A ++L+ALE ESKKL+EKEKAELQAKL+A+ KALKE+LAKQ EELAKLRA KA Sbjct: 404 EANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKA 463 Query: 261 AGSKTPATKPANKERSGR--AAQTATRPSQNKG----MRSQLPSTGEAANPFFTAAAATV 314 + S+TP KP NK G+ A Q T+P+QNK + QLPSTGE ANPFFTAAA TV Sbjct: 464 SDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTV 523 Query: 315 MVSAGMLALKRKEE 328 M +AG+ A+ +++E Sbjct: 524 MATAGVAAVVKRKE 537 Score = 52.8 bits (126), Expect = 9e-10 Identities = 51/250 (20%), Positives = 91/250 (36%), Gaps = 11/250 (4%) Query: 1 MTVLGAGFANQTEVRAEGVKATTNLPEKAKYDALRDENTGLRGDRTKLLKKLEEEQEKSK 60 +TVLGAG T + + + + +++ + L K + +K Sbjct: 26 LTVLGAGLVVNTNEVSAVATRS----QTDTLEKVQERADKFEIENNTLKLKNSDLSFNNK 81 Query: 61 NLEKQKQELENQALNFHDVIETQEKEKEDLKTTLAKTTKENEISEASRKGLSSDLEASRA 120 L+ EL + + +++ +L++ + + EA + L LE + Sbjct: 82 ALKDHNDELTEE-------LSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMN 134 Query: 121 AKKELEAKHQKLEAENKKLTEANQVSEASRKGLSNDLEASRAAKKELEAKHQKLEADYQV 180 AK + LEAE L E + +G N A A K LEA+ LEA Sbjct: 135 FSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAE 194 Query: 181 SETSRKGLSRDLEASREANKKVTSELTQAKAQLSALEESKKLSEKEKAELQAKLDAQGKA 240 E + +G A K + +E A+ + LE++ + + AK+ Sbjct: 195 LEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAE 254 Query: 241 LKEQLAKQTE 250 A+Q E Sbjct: 255 KAALEARQAE 264 Score = 40.4 bits (94), Expect = 7e-06 Identities = 50/211 (23%), Positives = 83/211 (39%) Query: 11 QTEVRAEGVKATTNLPEKAKYDALRDENTGLRGDRTKLLKKLEEEQEKSKNLEKQKQELE 70 + A+ L G T K++ + + LE ++ ELE Sbjct: 137 TADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELE 196 Query: 71 NQALNFHDVIETQEKEKEDLKTTLAKTTKENEISEASRKGLSSDLEASRAAKKELEAKHQ 130 + + + L+ A E + +G + A A K LEA+ Sbjct: 197 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKA 256 Query: 131 KLEAENKKLTEANQVSEASRKGLSNDLEASRAAKKELEAKHQKLEADYQVSETSRKGLSR 190 LEA +L +A + + S ++ A K LEA+ LE QV +R+ L R Sbjct: 257 ALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRR 316 Query: 191 DLEASREANKKVTSELTQAKAQLSALEESKK 221 DL+ASREA K++ +E + + Q E S++ Sbjct: 317 DLDASREAKKQLEAEHQKLEEQNKISEASRQ 347 Score = 37.7 bits (87), Expect = 5e-05 Identities = 51/232 (21%), Positives = 83/232 (35%) Query: 30 KYDALRDENTGLRGDRTKLLKKLEEEQEKSKNLEKQKQELENQALNFHDVIETQEKEKED 89 K L L + + K K LE +K L + + +E Sbjct: 114 KIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTA 173 Query: 90 LKTTLAKTTKENEISEASRKGLSSDLEASRAAKKELEAKHQKLEAENKKLTEANQVSEAS 149 + E EA + L LE + AK + LEAE L E + Sbjct: 174 DSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKA 233 Query: 150 RKGLSNDLEASRAAKKELEAKHQKLEADYQVSETSRKGLSRDLEASREANKKVTSELTQA 209 +G N A A K LEA+ LEA E + +G A K + +E Sbjct: 234 LEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAAL 293 Query: 210 KAQLSALEESKKLSEKEKAELQAKLDAQGKALKEQLAKQTEELAKLRAEKAA 261 +A+ + LE ++ + L+ LDA +A K+ A+ + + + +A+ Sbjct: 294 EAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEAS 345 Score = 37.7 bits (87), Expect = 5e-05 Identities = 51/238 (21%), Positives = 86/238 (36%), Gaps = 10/238 (4%) Query: 33 ALRDENTGLRGDRTKLLKKLEEEQEKSKNLEKQKQELENQALNFHDVIETQEKEKEDLKT 92 +++ ++ K++E + + +LEK + N + I+T E EK L Sbjct: 96 NAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAA 155 Query: 93 TLAKTTKENEISEASRKGLSSDLEASRAAKKELEAKHQKLEAENKKLTEANQVSEASRKG 152 A K E + S+ ++ A K LEA+ +LE + + A K Sbjct: 156 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKT 215 Query: 153 LSNDLEASRAAKKELEAKHQKLEADYQVSETSRKGLSRDLEASREANKKVTSELTQAKAQ 212 L + A A K +LE + K L + A ++ L A Sbjct: 216 LEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNF 275 Query: 213 LSALEESKKLSEKEKAELQAKL----------DAQGKALKEQLAKQTEELAKLRAEKA 260 +A K E EKA L+A+ +A ++L+ L E +L AE Sbjct: 276 STADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQ 333
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 100 bits (250), Expect = 2e-25 Identities = 148/308 (48%), Positives = 193/308 (62%), Gaps = 28/308 (9%) Query: 64 KENEELKVEREKYLSYADDKEKDPQYRALMGENQDLRKREGQYQDKIEELEKERKEKQER 123 N + A+ + + L + KI+ LE E+ + Sbjct: 237 AMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAE 296 Query: 124 QEQLERQYQIE--ADKHYQEQQKKHQQEQQQLEAEKQKLAKDKQISDASRQGLSRDLEAS 181 + LE Q Q+ + + ++ ++QLEAE QKL + +IS+ASRQ L RDL+AS Sbjct: 297 KADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS 356 Query: 182 REAKKKVEADLAALTAEHQKLKEDKQISDASRQGLSRDLEASREAKKKVEADLAEANSKL 241 REAKK++EA EHQKL+E +IS+ASRQ L RDL+ASREAKK+VE L EANSKL Sbjct: 357 REAKKQLEA-------EHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKL 409 Query: 242 QALEKLNKELEEGKKLSEKEKAELQARLEAEAKALKEQLAKQAEELAKLK-----GNQTP 296 ALEKLNKELEE KKL+EKEKAELQA+LEAEAKALKE+LAKQAEELAKL+ +QTP Sbjct: 410 AALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTP 469 Query: 297 NAKVAPQA--------------NRSRSAMTQQKRTLPSTGETANPFFTAAAATVMVSAGM 342 +AK +A N++++ M + KR LPSTGETANPFFTAAA TVM +AG+ Sbjct: 470 DAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGV 529 Query: 343 LALKRKEE 350 A+ +++E Sbjct: 530 AAVVKRKE 537 Score = 69.7 bits (170), Expect = 4e-15 Identities = 77/320 (24%), Positives = 122/320 (38%), Gaps = 4/320 (1%) Query: 1 MARKDTNKQYSLRKLKTGTASVAVAVAVLGAGFANQTEVKAAEIKKPQADSAWNWPKEYN 60 M + +TN+ YSLRKLKTGTASVAVA+ VLGAG T +A + Q D+ + + Sbjct: 1 MTKNNTNRHYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTLEKVQERAD 60 Query: 61 ALLKENEELKVEREKYLSYADDKEKDPQYRALMGENQDLRKREGQYQDKIEELEKERKEK 120 EN LK++ + L E + +++ + + E + +E Sbjct: 61 KFEIENNTLKLKNSDLSFNNKALKD--HNDELTEELSNAKEKLRKNDKSLSEKASKIQEL 118 Query: 121 QERQEQLERQYQI--EADKHYQEQQKKHQQEQQQLEAEKQKLAKDKQISDASRQGLSRDL 178 + R+ LE+ + + K + E+ L A K L K + + S + Sbjct: 119 EARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKI 178 Query: 179 EASREAKKKVEADLAALTAEHQKLKEDKQISDASRQGLSRDLEASREAKKKVEADLAEAN 238 + K +EA A L + A + L + A K +E L A Sbjct: 179 KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAM 238 Query: 239 SKLQALEKLNKELEEGKKLSEKEKAELQARLEAEAKALKEQLAKQAEELAKLKGNQTPNA 298 + A K LE K E +AEL+ LE AK A+ + A Sbjct: 239 NFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKA 298 Query: 299 KVAPQANRSRSAMTQQKRTL 318 + Q+ + +R L Sbjct: 299 DLEHQSQVLNANRQSLRRDL 318 Score = 31.6 bits (71), Expect = 0.005 Identities = 52/234 (22%), Positives = 90/234 (38%), Gaps = 21/234 (8%) Query: 57 KEYNALLKENEELKVEREKYLSYADDKEKDPQY-----RALMGENQDLRKREGQYQDKIE 111 A + + L+ E+ + D EK + A + + L + + + Sbjct: 134 NFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQA 193 Query: 112 ELEKERKEKQERQEQLERQYQIEADKH----------------YQEQQKKHQQEQQQLEA 155 ELEK + + + + + + LEA Sbjct: 194 ELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEA 253 Query: 156 EKQKLAKDKQISDASRQGLSRDLEASREAKKKVEADLAALTAEHQKLKEDKQISDASRQG 215 EK L + + + +G A K +EA+ AAL AE L+ Q+ +A+RQ Sbjct: 254 EKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQS 313 Query: 216 LSRDLEASREAKKKVEADLAEANSKLQALEKLNKELEEGKKLSEKEKAELQARL 269 L RDL+ASREAKK++EA+ + + + E + L S + K +L+A Sbjct: 314 LRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEH 367
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 129 bits (326), Expect = 2e-35 Identities = 117/346 (33%), Positives = 176/346 (50%), Gaps = 16/346 (4%) Query: 57 KEANKVFEERKALEKQARDLGDTINHMSQTISEQSRKIAALKSEAELKNQQALEALNNKN 116 E K E T+ ++ + + A + + Sbjct: 193 AELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLE 252 Query: 117 KQISDLTNENAQLKEAIEGYVQ-------TIQNASREIAAKQQELAAAKSQLEAKNAEIE 169 + + L A+L++A+EG + I+ E AA + E A + Q + NA + Sbjct: 253 AEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQ 312 Query: 170 ALKQQDASKTEEIAKLQSEAATLENLLGSAKRELTELQAKLDTATAEKAKLESQVTTLEN 229 +L++ + E +L++E LE ++ L+ LD + K +LE++ LE Sbjct: 313 SLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEE 372 Query: 230 LLGSAKRELTDLQAKLDAANAEKEKLQSQAATLEKQLEATKKELADLQAKLAATNQEKE- 288 ++ L+ LDA+ K++++ +L A +K +L+ T +EK Sbjct: 373 QNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAE 432 Query: 289 ---KLEAEAKALKEQLAKQAEELAKLKADKASGAQKPDTKPGNKEVPTR----PSQTRTN 341 KLEAEAKALKE+LAKQAEELAKL+A KAS +Q PD KPGNK VP + + T+ N Sbjct: 433 LQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPN 492 Query: 342 TNKAPMAQTKRQLPSTGEETTNPFFTAAALTVIASAGVLALKRKEE 387 NKAPM +TKRQLPSTG ET NPFFTAAALTV+A+AGV A+ +++E Sbjct: 493 QNKAPMKETKRQLPSTG-ETANPFFTAAALTVMATAGVAAVVKRKE 537 Score = 86.7 bits (214), Expect = 1e-20 Identities = 93/334 (27%), Positives = 149/334 (44%), Gaps = 19/334 (5%) Query: 1 MSKRNPNKLYSLRKLKTGTASVAVALTVLGTGLANTTDVKAESRRYQAPPRVLLQGKEAN 60 M+K N N+ YSLRKLKTGTASVAVALTVLG GL T+ + + + A+ Sbjct: 1 MTKNNTNRHYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTLEKVQERAD 60 Query: 61 KVFEERKALEKQARDLGDTINHMSQTISEQSRKIAALKSEAELKNQQALEALNNKNKQIS 120 K E L+ + DL + E + +++ K + KN ++L +K +++ Sbjct: 61 KFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLR-KNDKSLSEKASKIQELE 119 Query: 121 DLTNENAQLKEAIEGYVQTIQNASREIAAKQQELAAAKSQLEAKNAEIEALKQQDASKTE 180 + + E + + + A++ LAA K+ LE D++K + Sbjct: 120 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIK 179 Query: 181 EI----AKLQSEAATLENLLGSAKRELTELQAKLDTATAEKAKLESQVTTLENLLGSAKR 236 + A L++ A LE L A T AK+ T AEKA L ++ LE L A Sbjct: 180 TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 239 Query: 237 ELTDLQAKLDAANAEKEKLQSQAATLEK--------------QLEATKKELADLQAKLAA 282 T AK+ AEK L+++ A LEK +++ + E A L+A+ A Sbjct: 240 FSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKAD 299 Query: 283 TNQEKEKLEAEAKALKEQLAKQAEELAKLKADKA 316 + + L A ++L+ L E +L+A+ Sbjct: 300 LEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQ 333 Score = 29.6 bits (66), Expect = 0.022 Identities = 34/203 (16%), Positives = 74/203 (36%) Query: 123 TNENAQLKEAIEGYVQTIQNASREIAAKQQELAAAKSQLEAKNAEIEALKQQDASKTEEI 182 T+ +++E + + + + A K + E+ K++ + + Sbjct: 49 TDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSL 108 Query: 183 AKLQSEAATLENLLGSAKRELTELQAKLDTATAEKAKLESQVTTLENLLGSAKRELTDLQ 242 ++ S+ LE ++ L +A+ LE++ L ++ L Sbjct: 109 SEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAM 168 Query: 243 AKLDAANAEKEKLQSQAATLEKQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLA 302 A +A+ + L+++ A LE + +K L A + + + LEAE AL + A Sbjct: 169 NFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKA 228 Query: 303 KQAEELAKLKADKASGAQKPDTK 325 + L + + K T Sbjct: 229 DLEKALEGAMNFSTADSAKIKTL 251
>PF05043#Transcriptional activator Length = 493 Score = 536 bits (1383), Expect = 0.0 Identities = 107/491 (21%), Positives = 217/491 (44%), Gaps = 16/491 (3%) Query: 16 RELKLISYLTENSNVIGVKDKELSKALNISMLTLQSCLTNMQFMKEVGGITYKDGYINIW 75 R+L+L+ L E+ EL++ LN + ++ L++++ I I Sbjct: 11 RQLELLELLFEHKRWFHRS--ELAELLNCTERAVKDDLSHVKSAFPDLIFHSSTNGIRII 68 Query: 76 YHQCCGLQEVYQKALRESPSLKLLELLFFRDFSSLEELAEELFVSLSTLKRLIKKTNTYL 135 ++ VY + S +LE +FF + E + +E ++S S+L R+I + N + Sbjct: 69 NTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRIISQINKVI 128 Query: 136 SHTFAISIVTSPVQVSGDERQIRLFYLKYFSEAYKISEWPFGDILNLKNCERLLSLLIKE 195 F + +PVQ+ G+ER IR F+ +YFSE Y EWPF + + + +LL L+ KE Sbjct: 129 KRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFEN-FSSEPLSQLLELVYKE 187 Query: 196 VDVKVHFTLFQHLKILSGVNLIRYYKGYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYL 255 ++ + + LK+L NL R G+ + + + + + I+ +++ F Sbjct: 188 TSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEGVAQSFES 247 Query: 256 KFGLHLDEYTIAEMLSNHLNDKLEIGCAFEIINQDPTSGGRQVTNWIHLL----DEMEIK 311 ++ + LDE + ++ ++ I E + V HLL D++ +K Sbjct: 248 EYNISLDEEVVCQLFVSYFQKMFFID---ESLFMKCVKKDSYVEKSYHLLSDFIDQISVK 304 Query: 312 LNLSITNKYEVAVTLHNASVLNEEDITANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEK 371 + I NK + LHN + L +++ ++LFD K + + +Q P+ + Sbjct: 305 YQIEIENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDVKKELSH 364 Query: 372 LMQADNAQVSKELINQLTYCFFITWENSFLKVNQKDEKVRLLVI----ERSYNSVGNFLK 427 ++ S ++N L+Y F ++ + + Q K+++LV+ + V L Sbjct: 365 YLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLS 424 Query: 428 KYIGEFFSITNFDELDCLTIDLVEIEKQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDR 487 Y F + + EL+ L + YD+I+++ ++ E + + + ++I Sbjct: 425 YYCSNNFELEVWTELELSKESLE--DSPYDIIISNFIIPPIENKRLIYSNNINTVSLIYL 482 Query: 488 LNEFLNVSFTD 498 LN + + + Sbjct: 483 LNAMMFIRLDE 493
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 35.3 bits (81), Expect = 4e-04 Identities = 15/74 (20%), Positives = 18/74 (24%), Gaps = 2/74 (2%) Query: 119 PSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSADKAPEKGPEKAVEKTPEPNRD 178 P+P Q P Q P PE + PE E V + Sbjct: 44 PAP-AQPISVTMVAPADLEPP-QAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP 101 Query: 179 TPKPIQPPLAAAAP 192 PKP Sbjct: 102 KPKPKPVKKVEQPK 115 Score = 32.6 bits (74), Expect = 0.003 Identities = 14/87 (16%), Positives = 23/87 (26%), Gaps = 4/87 (4%) Query: 111 PNSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSADKAPEKGPE---- 166 P T ++ P P+ + + P+ E K Sbjct: 46 PAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP 105 Query: 167 KAVEKTPEPNRDTPKPIQPPLAAAAPV 193 K V+K +P RD P + Sbjct: 106 KPVKKVEQPKRDVKPVESRPASPFENT 132 Score = 32.3 bits (73), Expect = 0.004 Identities = 19/84 (22%), Positives = 29/84 (34%), Gaps = 6/84 (7%) Query: 139 PSPDQQKD---QTPDKTPEK---SADKAPEKGPEKAVEKTPEPNRDTPKPIQPPLAAAAP 192 P+P Q P P PE E PEP ++ P I+ P P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 103 Query: 193 VFAPWRESDKDLSKLKPSSRSSAA 216 P ++ ++ +KP A+ Sbjct: 104 KPKPVKKVEQPKRDVKPVESRPAS 127 Score = 30.3 bits (68), Expect = 0.017 Identities = 13/87 (14%), Positives = 25/87 (28%), Gaps = 4/87 (4%) Query: 108 TKQPNSSDQSTPSPKDQSSQKE-SQNKDGRPTPSPDQQKDQTPDKTPEKSADKAPEKGPE 166 + + P + + + +P P P + + P+ PE + Sbjct: 38 HQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKP 97 Query: 167 KAVEKTPEPNRDTPKPIQPPLAAAAPV 193 K K K ++ P PV Sbjct: 98 KPKPKPKPK---PVKKVEQPKRDVKPV 121
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 32.1 bits (73), Expect = 0.002 Identities = 14/62 (22%), Positives = 28/62 (45%), Gaps = 8/62 (12%) Query: 10 VINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKREFDQTSKQIKGKTVTEIRDILTKKI 69 V + LI+ ++ A+ + + KE +K+ +TEIRD+L ++ Sbjct: 82 VFDFLIVA------FAIFMAIKLINKLNRKKEEPAAAPAPTKEEV--LLTEIRDLLKEQN 133 Query: 70 NK 71 N+ Sbjct: 134 NR 135
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 1e-20 Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 1/128 (0%) Query: 3 KILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLE 62 ILV +DD I V+ + L YD + DL++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 VLKTIRKT-SDVPIIMLTALDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTP 121 +L I+K D+P+++++A + T + + DY+ KPF LI I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 DEKRQIGD 129 + D Sbjct: 125 RPSKLEDD 132
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 54.4 bits (131), Expect = 4e-10 Identities = 34/144 (23%), Positives = 55/144 (38%), Gaps = 10/144 (6%) Query: 60 DISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQPLFSYETSQRLTAQSSEF 119 +I T G++T + SK VK++ VK+G+ V+ G L +LTA +E Sbjct: 81 EIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLL------KLTALGAEA 134 Query: 120 DVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESLLEQIRSAEDSVSQAL 179 D + Q + A L+ Y I K PDE + + E +L Sbjct: 135 DTL----KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190 Query: 180 SDAKTADSDVKTAQIELDKANATA 203 + + + Q EL+ A Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRA 214 Score = 39.4 bits (92), Expect = 2e-05 Identities = 28/180 (15%), Positives = 61/180 (33%), Gaps = 16/180 (8%) Query: 120 DVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESL---LEQIRSAEDSVS 176 D + ++ +AK + Y VNE+ KS+ E L E + + Sbjct: 239 DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN 298 Query: 177 QALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKS 236 + L + ++ +EL K + + +++ + + L Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEE-------RQQASVIRAPVSVKVQQLKVHTEGGVV- 350 Query: 237 KKENETFMEII-DKSKMLVKGNISEFDRDKLKIGQKVEV-IDRKDNSK--KWTGKVTQVG 292 ET M I+ + + V + D + +GQ + ++ ++ GKV + Sbjct: 351 -TTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN 409
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 45.8 bits (108), Expect = 5e-07 Identities = 62/330 (18%), Positives = 108/330 (32%), Gaps = 49/330 (14%) Query: 290 KVVLSEEAPNLRTAKEKVKTLKGI--LHDYYVE-------TNDLEKAKEYHVEDETSPSQ 340 V L +L K K++ + G L++ VE T ++ + + PS Sbjct: 954 NVSLVGNTVDLGAWKYKLRNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSN 1013 Query: 341 PEAPAKP-EAPSPSPAPGQKPAEDERSSQATEPANPSKEDSSTDASQGSHDSENPATDSP 399 E A+ EAP P PAP E ++ ++ + + E + DA++ + + Sbjct: 1014 NEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNR------- 1066 Query: 400 SQPQAPDQGNHQSQVPNDKPQTDKTDTPNVPAPPQDTPKVPEAGGQSGPAGNAEEKAPDS 459 + K NV A Q T +V ++G ++ E K + Sbjct: 1067 --------------------EVAKEAKSNVKANTQ-TNEVAQSGSETKETQTTETKETAT 1105 Query: 460 GPKESDQ----SSSKESPSVGEDTTPNQPDVLVGGQSEPIDITEDTITDAPPTVSGHNAS 515 KE ++E P V +P Q QSE + + + PTV+ Sbjct: 1106 VEKEEKAKVETEKTQEVPKVTSQVSPKQE------QSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 516 TQPQSVVEDTAPQRPDVLVGGQSEPIDITQDTQPGMSGSNDATVINEDTKPKRVFHFDNK 575 +Q + + P + Q T +T + N T+P NK Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVV-ENPENTTPATTQPTVNSESSNK 1218 Query: 576 ESQASEKAAEQKLAPHDSHTTPQASDDTAA 605 ++ + TT T A Sbjct: 1219 PKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 34.7 bits (79), Expect = 0.002 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 5/117 (4%) Query: 33 STSASSTKTSASTNINTNTSTASAGTG---TSGTASTTPSVGTSTGGAAGGEAAVASSGG 89 T T ST T+ S AG G T+G +ST + STG A VA G Sbjct: 155 PTQTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGS 214 Query: 90 SQSS--ESAQASTQPQAQTAVAASASTTASPSSSEEKTPKTVTSSTSSTPAASSSSN 144 +Q++ ES+Q + QT + S T S+ ++ + ST A S+ Sbjct: 215 TQTAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSS 271 Score = 34.3 bits (78), Expect = 0.003 Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 8/148 (5%) Query: 12 SVGLVSVGTMLIAPTVLGQEVSTSASSTKTSASTNINTNTSTASAGTGTSGTASTTPSVG 71 S G + LIA Q ++ T ST S +AG G++GTA S+ Sbjct: 294 STGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLI 353 Query: 72 T---STGGAAGGEAAVASSGGSQSSESAQASTQPQAQTAVAASASTT-----ASPSSSEE 123 ST A + A G +Q+++ T T A + S+ ++ ++ EE Sbjct: 354 AGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEE 413 Query: 124 KTPKTVTSSTSSTPAASSSSNGNQVTGT 151 T ST + S + G TGT Sbjct: 414 STQTAGYGSTQTAQKGSDLTAGYGSTGT 441 Score = 32.8 bits (74), Expect = 0.009 Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 5/138 (3%) Query: 12 SVGLVSVGTMLIAPTVLGQEVSTSASSTKTSASTNINTNTSTASAGTGTSGTASTTPSV- 70 S G + LIA Q ++ T ST S +AG G++GTA S+ Sbjct: 390 STGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLI 449 Query: 71 -GTSTGGAAGGEAAV-ASSGGSQSSESAQASTQPQAQTAVAASASTTASPSSSEEKT--P 126 G + AG ++++ A G +Q+++ T T+ A S+ + S + Sbjct: 450 AGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYG 509 Query: 127 KTVTSSTSSTPAASSSSN 144 T+T+ ST A + S+ Sbjct: 510 STLTAGYGSTQTAQNESD 527 Score = 32.8 bits (74), Expect = 0.009 Identities = 32/138 (23%), Positives = 55/138 (39%), Gaps = 5/138 (3%) Query: 12 SVGLVSVGTMLIAPTVLGQEVSTSASSTKTSASTNINTNTSTASAGTGTSGTASTTPSV- 70 S + LIA Q S ++ T ST S +AG G++GTA + S+ Sbjct: 534 STSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSII 593 Query: 71 -GTSTGGAAGGEAAV-ASSGGSQSSESAQASTQPQAQTAVAASASTTASPSSSEEKT--P 126 G + A +++ A G +Q++ T T+ A + S+ + S + Sbjct: 594 AGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYN 653 Query: 127 KTVTSSTSSTPAASSSSN 144 +T+ ST A S+ Sbjct: 654 SILTAGYGSTQTAQEGSD 671 Score = 32.4 bits (73), Expect = 0.011 Identities = 37/148 (25%), Positives = 56/148 (37%), Gaps = 8/148 (5%) Query: 12 SVGLVSVGTMLIAPTVLGQEVSTSASSTKTSASTNINTNTSTASAGTGTSGTASTTPSVG 71 S G + LIA Q +S T ST S +AG G++ TA S+ Sbjct: 438 STGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLI 497 Query: 72 T---STGGAAGGEAAVASSGGSQSSESAQASTQPQAQTAVAASASTTASPSSSEEKTP-- 126 ST A G A G +Q++++ T+ A + S+ + S + Sbjct: 498 AGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYN 557 Query: 127 KTVTSSTSSTPAASSSSN---GNQVTGT 151 +T+ ST A S+ G TGT Sbjct: 558 SVLTAGYGSTQTAREGSDLTAGYGSTGT 585 Score = 31.6 bits (71), Expect = 0.017 Identities = 37/148 (25%), Positives = 58/148 (39%), Gaps = 8/148 (5%) Query: 12 SVGLVSVGTMLIAPTVLGQEVSTSASSTKTSASTNINTNTSTASAGTGTSGTASTTPSV- 70 S G + LIA Q +S T ST S +AG G++GTA S+ Sbjct: 246 STGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLI 305 Query: 71 -GTSTGGAAGGEAA-VASSGGSQSSESAQASTQPQAQTAVAASASTT-----ASPSSSEE 123 G + AG E+ A G +Q+++ T T A S+ ++ ++ E+ Sbjct: 306 AGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGED 365 Query: 124 KTPKTVTSSTSSTPAASSSSNGNQVTGT 151 + ST + S + G TGT Sbjct: 366 SSLTAGYGSTQTAQKGSDLTAGYGSTGT 393 Score = 31.6 bits (71), Expect = 0.020 Identities = 36/148 (24%), Positives = 56/148 (37%), Gaps = 8/148 (5%) Query: 12 SVGLVSVGTMLIAPTVLGQEVSTSASSTKTSASTNINTNTSTASAGTGTSGTASTTPSVG 71 S G + L+A Q +S ST S +AG G++GTA S+ Sbjct: 198 STGTAGADSTLVAGYGSTQTAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLI 257 Query: 72 T---STGGAAGGEAAVASSGGSQSSESAQASTQPQAQTAVAASASTT-----ASPSSSEE 123 ST A + A G +Q+++ T T A + S+ ++ ++ EE Sbjct: 258 AGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEE 317 Query: 124 KTPKTVTSSTSSTPAASSSSNGNQVTGT 151 T ST + S + G TGT Sbjct: 318 STQTAGYGSTQTAQKGSDLTAGYGSTGT 345 Score = 31.6 bits (71), Expect = 0.021 Identities = 36/148 (24%), Positives = 57/148 (38%), Gaps = 8/148 (5%) Query: 12 SVGLVSVGTMLIAPTVLGQEVSTSASSTKTSASTNINTNTSTASAGTGTSGTASTTPSV- 70 S G + LIA Q +S T ST S +AG G++GTA S+ Sbjct: 342 STGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLI 401 Query: 71 -GTSTGGAAGGEAA-VASSGGSQSSESAQASTQPQAQTAVAASASTT-----ASPSSSEE 123 G + AG E+ A G +Q+++ T T A S+ ++ ++ E+ Sbjct: 402 AGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGED 461 Query: 124 KTPKTVTSSTSSTPAASSSSNGNQVTGT 151 + ST + S + G T T Sbjct: 462 SSLTAGYGSTQTAQKGSDLTAGYGSTST 489 Score = 31.3 bits (70), Expect = 0.023 Identities = 35/144 (24%), Positives = 54/144 (37%), Gaps = 7/144 (4%) Query: 12 SVGLVSVGTMLIAPTVLGQEVSTSASSTKTSASTNINTNTSTASAGTGTSGTASTTPSV- 70 S G + +IA Q S +S T ST S + G G++ TA S+ Sbjct: 582 STGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLI 641 Query: 71 -GTSTGGAAGGEAAVASSGGSQSSESAQASTQPQAQTAVAASASTTASPSSSEEKTPKTV 129 G + AG + + + G S Q + + TA S ST + SS T Sbjct: 642 AGYGSTQTAGYNSILTAGYG-----STQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQ 696 Query: 130 TSSTSSTPAASSSSNGNQVTGTEV 153 T+ +S A S G+++ Sbjct: 697 TAGYNSILTAGYGSTQTAQEGSDL 720 Score = 30.5 bits (68), Expect = 0.041 Identities = 32/138 (23%), Positives = 48/138 (34%), Gaps = 5/138 (3%) Query: 12 SVGLVSVGTMLIAPTVLGQEVSTSASSTKTSASTNINTNTSTASAGTGTSGTASTTPSVG 71 S + LIA Q ++ T ST N S G G++ TA S+ Sbjct: 486 STSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLI 545 Query: 72 T---STGGAAGGEAAVASSGGSQSSESAQASTQPQAQTAVAASASTTASPSSSEEKT--P 126 ST A+ A G +Q++ T T A S S+ + S + Sbjct: 546 AGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYH 605 Query: 127 KTVTSSTSSTPAASSSSN 144 ++T+ ST A S Sbjct: 606 SSLTAGYGSTQTAREQSV 623 Score = 30.5 bits (68), Expect = 0.043 Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 5/105 (4%) Query: 44 STNINTNTSTASAGTGTSGTASTTPSVGT---STGGAAGGEAAVASSGGSQ--SSESAQA 98 ST S +AG G++ TA + + ST A + +A G +Q S S+ Sbjct: 694 STQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLT 753 Query: 99 STQPQAQTAVAASASTTASPSSSEEKTPKTVTSSTSSTPAASSSS 143 + QTA S TT S+S ++ + ST A S Sbjct: 754 AGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHS 798
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 27.2 bits (60), Expect = 0.006 Identities = 6/24 (25%), Positives = 9/24 (37%) Query: 22 YSKKVLADEPTSYQPPAAHSPCDD 45 + + A + T AA S D Sbjct: 27 KNPQPQAQQTTQTTTTAAGSAADQ 50
>STREPTOPAIN#Streptopain (C10) cysteine protease family signature. Length = 398 Score = 59.3 bits (143), Expect = 6e-14 Identities = 39/102 (38%), Positives = 56/102 (54%), Gaps = 7/102 (6%) Query: 2 EMHFVRTEPEARRIAETFCAENTQTKTPMRVQQLSYPSDTDHSGGEL-----YIYALSPA 56 + +F R E EA+ A TF ++ K R + D + GGEL Y+Y +S Sbjct: 28 DQNFARNEKEAKDSAITFIQKSAAIKAGARSAE-DIKLDKVNLGGELSGSNMYVYNISTG 86 Query: 57 GFIIVSGDTRAHTILGYSFDNNLDLN-HDNVRSMVEAYQKQI 97 GF+IVSGD R+ ILGYS + D N +N+ S +E+Y +QI Sbjct: 87 GFVIVSGDKRSPEILGYSTSGSFDANGKENIASFMESYVEQI 128
>STREPTOPAIN#Streptopain (C10) cysteine protease family signature. Length = 398 Score = 711 bits (1835), Expect = 0.0 Identities = 395/398 (99%), Positives = 396/398 (99%) Query: 1 MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAITFIQKSAAIKAGARSTE 60 MNKKKLG+RLLSLLALGGFVLANPVFADQNFARNEKEAKDSAITFIQKSAAIKAGARS E Sbjct: 1 MNKKKLGVRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAITFIQKSAAIKAGARSAE 60 Query: 61 DIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILGYSTSGSFDANGKENIASF 120 DIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILGYSTSGSFDANGKENIASF Sbjct: 61 DIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILGYSTSGSFDANGKENIASF 120 Query: 121 MESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGE 180 MESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGE Sbjct: 121 MESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGE 180 Query: 181 QSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQY 240 QSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQY Sbjct: 181 QSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQY 240 Query: 241 NWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQ 300 NWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQ Sbjct: 241 NWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQ 300 Query: 301 SVHQINRSDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWG 360 SVHQINR DFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWG Sbjct: 301 SVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWG 360 Query: 361 GVSDGFFRLDALNPSALGTGGGAGGFNGYQSAVVGIKP 398 GVSDGFFRLDALNPSALGTGGGAGGFNGYQSAVVGIKP Sbjct: 361 GVSDGFFRLDALNPSALGTGGGAGGFNGYQSAVVGIKP 398
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 30.0 bits (67), Expect = 0.022 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 22/145 (15%) Query: 242 GGQVMETVGIENMIGTLYT--EGPKLMAEVEAHTKSYDVDIIKAQLATSIEKKENIEVTL 299 G M+ G+E +GTL E P + A + + + +DI+K K++ + T Sbjct: 205 NGSAMQIRGVEKALGTLKITHENPNVEANYDENAAALSIDIVK--------KQKGGKGTA 256 Query: 300 ANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGVTYCPHCDGPLFEGKDVAVIGGGNSG 359 A G + + + + RN+ +D+F K DG + K + GN Sbjct: 257 AQGIYINSTSGTTGKLLRIRNLG---DDKFYVKH-------DGGFYAKKTSQI--DGNLK 304 Query: 360 LEAALDLAGLAKHVYVLEFLPELKA 384 L+ A YV + +LKA Sbjct: 305 LKNPTADDHAATKAYVDSEVKKLKA 329
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 44.3 bits (105), Expect = 7e-07 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 6/53 (11%) Query: 46 IAIKDSLIVALG-SGEPDAE-----LVGPQTIMRSYKGKIATPGIIDCHTHLV 92 I +KD I A+G +G PD + +VGP T + + +GKI T G +D H H + Sbjct: 88 IGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFI 140
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.8 bits (69), Expect = 0.020 Identities = 20/118 (16%), Positives = 35/118 (29%), Gaps = 17/118 (14%) Query: 438 NAYYDPQQNQIVFPAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDT---------N 488 + + A + S+ N+ +G + + N Sbjct: 594 YLNLENYTYYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFN 653 Query: 489 GASFDEHGSLNDWWTQEDYAAFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGG 546 G +E G N FK ++++ G G +NG LTV + L G Sbjct: 654 GYFGEEEGKNNGNLN----VTFKGKSEQNRFLLTG----GTNLNGDLTVEKGTLFLSG 703
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.007 Identities = 6/18 (33%), Positives = 12/18 (66%) Query: 610 LVKQGDQVKAGQTLIQFD 627 +VK+G+ V+ G L++ Sbjct: 111 IVKEGESVRKGDVLLKLT 128
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 90.3 bits (224), Expect = 3e-22 Identities = 65/341 (19%), Positives = 135/341 (39%), Gaps = 22/341 (6%) Query: 37 KKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRS--QLLQLDYVLKMEESLLKGQGLAD 94 +LS+ + LA L++ E + + + + + + +++G LAD Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 95 MLSGLG--FSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRRKTVEVITYPLILLLF 152 + F ++ + G+++ L + Y Q ++R + + + YP +L + Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 153 LFVMMLGLRRYLVPQLETQNQ---------------ITYFLNHFPAFFIGFCSGLILLFG 197 ++ L +VP++ Q ++ + F + + + F Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 198 MVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDIMAIE 257 + LR + + R+ + RL P +G++ + T+ YAR L + L+ + I Sbjct: 243 V-MLR-QEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 258 KSSL-MKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELEIYAQE 316 S+ + ++ EG + H + F + MI GE +L + LE A Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 317 SWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQ 357 +F SQ+ L +P + + +A ++ I AIL PI Q Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQ 401 Score = 34.8 bits (80), Expect = 4e-04 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 6/129 (4%) Query: 235 REWGTLIGQGLDLMTILDIMAIE-KSSLMKELAEDIRMSLLEGQAFHIKVATYP-FFKKE 292 R+ TL+ + L LD +A + + + +L +R ++EG + + +P F++ Sbjct: 75 RQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADAMKCFPGSFERL 134 Query: 293 LSLMIEYGEIKSKLGAELEIYA--QESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAA 350 M+ GE L A L A E +Q S++ Q +I P + VVA+ +V I + Sbjct: 135 YCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQA--MIYPCVLTVVAIAVVSILLS 192 Query: 351 ILLPIYQNM 359 +++P Sbjct: 193 VVVPKVVEQ 201
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 52.2 bits (125), Expect = 7e-12 Identities = 27/89 (30%), Positives = 49/89 (55%), Gaps = 4/89 (4%) Query: 14 KGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKP 73 +GFTLLE+++VI++I VL L VPNL K++ + + + +EN ++Y+L P Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHYP 67 Query: 74 SLSQ-LKA--DGSITEKQEKAY-QDYYDK 98 + +Q L++ + Y ++ Y K Sbjct: 68 TTNQGLESLVEAPTLPPLAANYNKEGYIK 96
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 26.9 bits (59), Expect = 0.034 Identities = 17/71 (23%), Positives = 25/71 (35%), Gaps = 9/71 (12%) Query: 37 LLKRSHYLARHDQDNWLLFSHQL--REELSGARFYKVADNK-LYVEKGKKVLAFGQFKSH 93 K S ++ D D ++ R ++ +Y VA N YV KV G + Sbjct: 217 TFKYSGWVESSDNDEHYDPGKRITYRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRV 276 Query: 94 DFRKSASNGKG 104 N KG Sbjct: 277 T------NKKG 281
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 498 bits (1285), Expect = e-179 Identities = 208/401 (51%), Positives = 280/401 (69%), Gaps = 7/401 (1%) Query: 3 KTIAINAGSSSLKWQLYQMPEEAVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTE 62 K + IN GSSSLK+QL + + VLA+G+ ERIG+ DS+ T +G+K + D+ DH + Sbjct: 2 KILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKD 61 Query: 63 AVKILLNDLI--HFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEQIEELSVLAPL 120 A+K++L+ L+ +G+I EI VGHRVV GGE F SV++ D VL+ I + LAPL Sbjct: 62 AIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121 Query: 121 HNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGT 180 HNP GI+A I+PD+ V VFDT+FH +M + YLYPIP +YYT YK+RKYG HGT Sbjct: 122 HNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGT 181 Query: 181 SHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGQSADTSMGFTPLAGPMMGTRS 240 SHKYV+Q AA++L +P+E LK+IT H+GNG SI A +G+S DTSMGFTPL G MGTRS Sbjct: 182 SHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRS 241 Query: 241 GDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDI-EAGLQEDNPDAV 299 G IDP+II YL+E+ E A +VVN+LNKKSG+ G+SGISSD RD+ +A + + A Sbjct: 242 GSIDPSIISYLMEK--ENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQ 299 Query: 300 LAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKN 359 LA N+F R+KK IG Y A + G D +VFTAG+GEN P +R+ ++ GL + G +D EKN Sbjct: 300 LALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKN 359 Query: 360 -VFGYRGDISTPESKVKVLVISTDEELCIARDVERL-KNTK 398 V G IST +SKV V+V+ T+EE IA+D E++ ++ K Sbjct: 360 KVRGEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIVESLK 400
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 97.1 bits (241), Expect = 7e-25 Identities = 46/123 (37%), Positives = 65/123 (52%), Gaps = 8/123 (6%) Query: 23 SLTAAQAILESGWGKHA-------PHNALFGIKADASWTGKSFNTKTQEEYQAGVITDIV 75 L AQA LESGWG+ P LFG+KA +W G T E Y+ G + Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230 Query: 76 DRFRAYDSWDESIADHGQFLVDNPRYQSVIGEADYKKACHAIKDAGYATASGYAELLIQI 135 +FR Y S+ E+++D+ L NPRY +V A ++ A++DAGYAT YA L + Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290 Query: 136 IEE 138 I++ Sbjct: 291 IQQ 293
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 173 bits (440), Expect = 6e-56 Identities = 61/255 (23%), Positives = 117/255 (45%), Gaps = 28/255 (10%) Query: 5 HIIKIVFIITVILISTISPIIKSDSKKDISNVKSDLLYAYTITPYDYKDCRVNFSTT--- 61 +I I +I VI + + D D + S+ Y Y D V+ + Sbjct: 9 RVILIFALILVISTPNVLAESQPDPMPDDLHKSSEFTGTMGNMKYLYDDHYVSATKVKSV 68 Query: 62 -----HTL--NIDTQKYRGKDYYISSEMSYEASQKFKRDDHVDVFGLFYILNSHTGEY-- 112 H L NI +K + D + ++ + ++K+K D+ VDV+G Y +N + Sbjct: 69 DKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYK-DEVVDVYGSNYYVNCYFSSKDN 127 Query: 113 ----------IYGGITPAQNNKVNHKLLGNLFIS-GESQQN-LNNKIILEKDIVTFQEID 160 +YGGIT + N ++ L N+ + E+++N ++ ++ +K VT QE+D Sbjct: 128 VGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTAQELD 187 Query: 161 FKIRKYLMDNYKIYD-ATSPYVSGRIEIGTKDGKHEQIDLFDSPNEG-TRSDIFAKYKDN 218 K R +L++ +Y+ +SPY +G I+ +G D+ +P + +S Y DN Sbjct: 188 IKARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDN 247 Query: 219 RIINMKNFSHFDIYL 233 + ++ K+ +++L Sbjct: 248 KTVDSKS-VKIEVHL 261
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 29.6 bits (66), Expect = 0.018 Identities = 19/98 (19%), Positives = 28/98 (28%), Gaps = 8/98 (8%) Query: 154 FEQEDQLSKVKHLGAVTKVFKDTNQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQ 213 FE ++K + N P S A S K + G Q Sbjct: 83 FEALKAINKQTGIEIN-------NVEPSSNFESAYNSALSAGHKIWVLNGFKHQQS-IKQ 134 Query: 214 FISDHPELKQRYNIINITGDPHLNELSSHLYRVDYVTD 251 +I H E +R I I D + Y + + Sbjct: 135 YIDAHREELERNQIKIIGIDFDIETEYKWFYSLQFNIK 172
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 186 bits (473), Expect = 4e-53 Identities = 102/477 (21%), Positives = 187/477 (39%), Gaps = 97/477 (20%) Query: 8 IRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQE--RAMDSNDLEKERGITILAKNTA 65 I N+ ++AHVD GKTTL + LL S + E + + D+ LE++RGITI T+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 66 VAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQNLI 125 + + ++NI+DTPGH DF EV R + ++DG +L++ A +G QTR + + + Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 126 PIVVVNKIDKPSARP-------------------------------------AEVVDEVL 148 I +NKID+ + V E Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182 Query: 149 ELFIELGADDEQLE-----------------FPVVYASAINGTSSLSDDPADQEHTMAPI 191 + +E + LE FPV + SA N + + Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIG------------IDNL 230 Query: 192 FDTIIDHIPAPVDNSDEPLQFQVSLLDYNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTT 251 + I + + L +V ++Y++ R+ R++ G + + D V +S Sbjct: 231 IEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRIS----EK 286 Query: 252 KNFRVTKLFGFFGLERREIQEAKAGDLIAVSGMEDIFVGETITPTDCVEALPILRIDEPT 311 + ++T+++ E +I +A +G+++ + E + + + T + + P Sbjct: 287 EKIKITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPL 345 Query: 312 LQMTFLVNNSPFAGREGKWITSRKVEER--LLAELQT----DVSLRVDPTDSPDKWTVSG 365 LQ T + K ++R LL L D LR + + +S Sbjct: 346 LQTT---------------VEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSF 390 Query: 366 RGELHLSILIETMRRE-GYELQVSRPEVIIKEIDGVKCEPFERVQIDTPEEYQGAII 421 G++ + + ++ + E+++ P VI E K E + I+ P A I Sbjct: 391 LGKVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAE--YTIHIEVPPNPFWASI 445 Score = 42.5 bits (100), Expect = 4e-06 Identities = 18/79 (22%), Positives = 31/79 (39%), Gaps = 1/79 (1%) Query: 403 EPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPARGLIGYSTEFLS 462 EP+ +I P+EY + +++D Q + N + L IPAR + Y ++ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRSDLTF 595 Query: 463 MTRGYGIMNHTFDQYLPVV 481 T G + Y Sbjct: 596 FTNGRSVCLTELKGYHVTT 614
>PF03309#Bvg accessory factor Length = 271 Score = 29.3 bits (66), Expect = 0.017 Identities = 28/126 (22%), Positives = 42/126 (33%), Gaps = 14/126 (11%) Query: 5 LLGIDLGGTTIKFGILTAAGEVQE---KWAIETNILEGGKHIVPDIIASIKHRLDLYDLS 61 LL ID+ T G+++ +G+ + +W I T + D +A L Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTE-----PEVTADELALTIDG--LIGDD 54 Query: 62 SADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVEKELGIPFAIDNDANVAALG 121 + G S V + V W V GIP +DN V A Sbjct: 55 AERLTGASGLS--TVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVGA-- 110 Query: 122 ERWVGA 127 +R V Sbjct: 111 DRIVNC 116
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 578 bits (1492), Expect = 0.0 Identities = 191/410 (46%), Positives = 276/410 (67%), Gaps = 9/410 (2%) Query: 5 TPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDE 64 PI+++SEIG+LKKVLLHRPG+E+ENL P ++ LFDDIP+LE A++EH+ FA L++ Sbjct: 6 NPINIFSEIGRLKKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQEHEVFASILKNN 65 Query: 65 GIEVLYLETLAAESLVTP-EIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEK 123 +E+ Y+E L +E LV+ + FI +++ EA I+ T +++ ++ +I K Sbjct: 66 LVEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINLLKDYFSSL-TIDNMISK 124 Query: 124 TMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSE 183 ++GV EL +S L DLV F IDPMPN+ FTRDPFA+IG GV++N MF++ Sbjct: 125 MISGVVTEELKNYTSS---LDDLVNGANLFIIDPMPNVLFTRDPFASIGNGVTINKMFTK 181 Query: 184 TRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAA 243 R RET++ +YIF +HP+Y VP+ +R E +EGGDELVL+K +L +GIS+RT+A Sbjct: 182 VRQRETIFAEYIFKYHPVYKE-NVPIWLNRWEEASLEGGDELVLNKGLLVIGISERTEAK 240 Query: 244 SIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSV 303 S+EKL +++FK F +LAF+ NR +MHLDTVFT +DY FT + +Y + Sbjct: 241 SVEKLAISLFKNKTSFDTILAFQIPKNRSYMHLDTVFTQIDYSVFTSFTSDDMYFSIYVL 300 Query: 304 TYDNE--ELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAP 361 TY+ ++HI +EK + ++L+ LG K+D+I+C G +L+ REQWNDG+N L IAP Sbjct: 301 TYNPSSSKIHIKKEKARIKDVLSFYLG-RKIDIIKCAGGDLIHGAREQWNDGANVLAIAP 359 Query: 362 GVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI 411 G ++ Y+RN +TN + E G+K+ +I SEL RGRGGPRCMSMP REDI Sbjct: 360 GEIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGPRCMSMPLIREDI 409
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 124 bits (314), Expect = 2e-39 Identities = 61/146 (41%), Positives = 92/146 (63%), Gaps = 2/146 (1%) Query: 1 MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDT 60 MNK + RH IR +I+ I TQ EL + L+K+G +TQAT+SRD+KEL+LVKV + N + Sbjct: 1 MNKGQ-RHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGS 59 Query: 61 HYEALAISQTRWEH-RLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIV 119 + +L Q +L+ + DA V + H I+LKT+PG AQ+ G+++D + EI+ Sbjct: 60 YKYSLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEEIM 119 Query: 120 ATICGDDTCLIVCEDNEQAKACYETL 145 TICGDDT LI+C ++ K + + Sbjct: 120 GTICGDDTILIICRTHDDTKVVQKKI 145
>PF06580#Sensor histidine kinase Length = 349 Score = 182 bits (464), Expect = 1e-54 Identities = 57/203 (28%), Positives = 101/203 (49%), Gaps = 10/203 (4%) Query: 362 EKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGN- 420 + +L AL +QINPHF++N L+ I + D + E+ SL++ R +L N Sbjct: 155 ASMAQEAQLMALKAQINPHFMFNALNNIRALIL-EDPTKAREMLTSLSELMRYSLRYSNA 213 Query: 421 EYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIK 480 + LADEL V YL + ++ D+L +E Q D +P +++Q LVEN I HGI Sbjct: 214 RQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA 273 Query: 481 EVDRKGMIKVTVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHY 540 ++ + G I + + + L V + G ++ ++ G GL+NV +RL++ Y Sbjct: 274 QLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKEST-------GTGLQNVRERLQMLY 326 Query: 541 GEGYHMTIHSQSDQFTEIQLSLP 563 G + + + + + + +P Sbjct: 327 GTEAQIKLSEKQGKVNAM-VLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.1 bits (239), Expect = 6e-25 Identities = 42/165 (25%), Positives = 75/165 (45%), Gaps = 12/165 (7%) Query: 3 SLLIVEDEYLIRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLN 62 ++L+ +D+ IR + + + + V N W D+V+TD+ MP N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY---DVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GIQLAELIKEHAPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLRKK 122 L IK+ P ++ ++ + F A+ A + GA DYL KPF D+ +++G + + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF---DLTELIGIIGRA 118 Query: 123 LDLSKKTETIQELVEQPQKEVSAIAMAIHE------QLADSDLTL 161 L K+ + E Q + + A+ E +L +DLTL Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 28.6 bits (64), Expect = 0.040 Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Query: 264 LASVATSIVGVVSFLGL---IVPHMSRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLA 320 + S A + +GL H S+L++ Q +PFS L V + L Sbjct: 29 VVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQSYLPFSQALSYVVDNVLLEFF-YLC 87 Query: 321 YPLEISPAIIMSIVGG 336 +PL ++ A +M+I Sbjct: 88 FPL-LTVAALMAIASH 102
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 68.4 bits (167), Expect = 2e-15 Identities = 56/266 (21%), Positives = 102/266 (38%), Gaps = 26/266 (9%) Query: 29 VACVNQHPKTAKETEQQRIVATSVAVVDICDRLNLDLVGVCDSKLYTL----PKRYDAVK 84 + A + RIVA V++ L + GV D+ Y L P D+V Sbjct: 20 PLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVI 79 Query: 85 RVGLPMNPDIELIASLKPTWILSPNSLQEDLEPKYQKLDTEYGFLNLRSVEG------MY 138 VGL P++EL+ +KP++++ P + L +G Sbjct: 80 DVGLRTEPNLELLTEMKPSFMV----WSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMAR 135 Query: 139 QSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAKRKGK-KKPKVLILMGLPGSYLVATNQS 197 +S+ ++ +L Q A+ QY+D+ R+ + + + +P +L + P LV S Sbjct: 136 KSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNS 195 Query: 198 YVGNLLDLAGGENVYQSDEKEFLSANP---EDMLA-KEPDLILRTAHAIPDKVKVMFDKE 253 +LD G N +Q E F + + + A K+ D++ D +M Sbjct: 196 LFQEILDEYGIPNAWQG-ETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALM---- 250 Query: 254 FAENDIWKHFTAVKEGKVYDLDNTLF 279 +W+ V+ G+ + F Sbjct: 251 --ATPLWQAMPFVRAGRFQRVPAVWF 274
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 30.3 bits (68), Expect = 0.015 Identities = 14/42 (33%), Positives = 17/42 (40%) Query: 117 KPTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLPEVRT 158 KP KP K +QPK V++ PAS P T Sbjct: 93 KPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLT 134
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 345 bits (888), Expect = e-120 Identities = 122/367 (33%), Positives = 194/367 (52%), Gaps = 21/367 (5%) Query: 7 RPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQVSKALLPQVDGYCVSN 66 RP A ++LQA+K+N++ V++ + ++VVKA+AYGHG ++ A+ DG+ + N Sbjct: 3 RPIQASLDLQALKQNLSIVRQAAT-HARVWSVVKANAYGHGIERIWSAI-GATDGFALLN 60 Query: 67 LDEALQLRQAGIDKEILIL-GVLLPNELKLAITRQVTVTVASLEWLAMAKQEWPDLKG-L 124 L+EA+ LR+ G IL+L G +L++ ++T V S L + LK L Sbjct: 61 LEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNA--RLKAPL 118 Query: 125 KVHIKIDSGMGRIGLRSVTEVDNLIAGLKSMGA-EVEGIFTHFATADEADDTKFNQQLQF 183 +++K++SGM R+G + V + L++M + +HFA A+ D + Sbjct: 119 DIYLKVNSGMNRLGFQP-DRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGIS--GAMAR 175 Query: 184 FKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVRLGIVSYGLNPSGS-DLSLPFPLQEA 242 ++ GL SNSA ++WH + F+ VR GI+ YG +PSG L+ Sbjct: 176 IEQAAEGL---ECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPV 232 Query: 243 LSLESSLVHVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNM-QGFSVLVDGQF 301 ++L S ++ V+ + AG+ VGYG YTA+ + +G V GYADG+ R+ G VLVDG Sbjct: 233 MTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVR 292 Query: 302 CEIIGRVSMDQLTIRLPKA--YPLGTKVTLIGSNQQKNISTTDIANYRNTINYEVLCLLS 359 +G VSMD L + L +GT V L G K I D+A T+ YE++C L+ Sbjct: 293 TMTVGTVSMDMLAVDLTPCPQAGIGTPVELWG----KEIKIDDVAAAAGTVGYELMCALA 348 Query: 360 DRIPRIY 366 R+P + Sbjct: 349 LRVPVVT 355
>SECA#SecA protein signature. Length = 901 Score = 1052 bits (2723), Expect = 0.0 Identities = 394/903 (43%), Positives = 560/903 (62%), Gaps = 73/903 (8%) Query: 1 MANILRKVIENDKG-ELRKLEKIAKKVESYADQMASLSDRDLQGKTLEFKERYQKGETLE 59 + +L KV + LR++ K+ + + +M LSD +L+GKT EF+ R +KGE LE Sbjct: 2 LIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLE 61 Query: 60 QLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNAI 119 L+PEAFAVVREA+KRV G+ + VQ++GG+VL+ + EMRTGEGKTLTAT+P YLNA+ Sbjct: 62 NLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL 121 Query: 120 AGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKSPAEKREAYNCDITYSTNSE 179 G+GVHV+TVN+YL+ RDA ++ +LGL+VGINL KREAY DITY TN+E Sbjct: 122 TGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNE 181 Query: 180 VGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRAD 239 GFDYLRDNM E+ VQR L++ALVDEVDS+LIDEARTPLI+SG + ++Y R + Sbjct: 182 YGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSS-EMYKRVN 240 Query: 240 MFVKTLT------------SVDYVIDVPTKTIGLSDSGIDKAESYFNLS-------NLYD 280 + L + +D ++ + L++ G+ E +LY Sbjct: 241 KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS 300 Query: 281 IENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGLHQAIEA 340 N+ L H + ALRA+ + D+DY+V +DGE++IVD+ TGRTM+GRR+SDGLHQA+EA Sbjct: 301 PANIMLMHHVTAALRAHALFTRDVDYIV-KDGEVIIVDEHTGRTMQGRRWSDGLHQAVEA 359 Query: 341 KEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIA 400 KEGV+IQ E++T ASIT+QN FR+Y+KLAGMTGTA TE EF +Y + + +PTNRP+ Sbjct: 360 KEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMI 419 Query: 401 RIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKLVEAGIPHEVL 460 R D DL+Y T K +A++ED+K R AKGQP+LVGT+++E S+L+S +L +AGI H VL Sbjct: 420 RKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVL 479 Query: 461 NAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLG----------------------- 497 NAK H EA I+ AG AVTIATNMAGRGTDI LG Sbjct: 480 NAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKA 539 Query: 498 ------EGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFG 551 + V E GGL +IGTERHESRRIDNQLRGRSGRQGD G S+FYLS+ED LMR F Sbjct: 540 DWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFA 599 Query: 552 SDRIKAFLDRMKLDEEDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREI 611 SDR+ + ++ + + I+ + + + +AQ++VE N+D RKQ+L+YDDV +QR Sbjct: 600 SDRVSGMMRKLGM-KPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRA 658 Query: 612 IYANRRDVITANRDLGPEIKAMIKRTIDRAVDAHARSNR---KDAVDAIVTFARTSLVPE 668 IY+ R +++ + D+ I ++ + +DA+ + + + + Sbjct: 659 IYSQRNELLDVS-DVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLD 717 Query: 669 ESIS--AKELRGLKDEQIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWT 726 I+ + L +E ++E++ +++ +Y ++ + E + F+K ++L +D+ W Sbjct: 718 LPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVG-AEMMRHFEKGVMLQTLDSLWK 776 Query: 727 EHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIH-EQE 785 EH+ A+D LR + LRGYAQ +P EY+ E F MF M+ +++++V T+ K Q+ +E Sbjct: 777 EHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEE 836 Query: 786 RERASQRATTAAPQNIQSQQSANTDD-------------LPKVERNEACPCGSGKKFKNC 832 E Q+ A + Q QQ ++ DD KV RN+ CPCGSGKK+K C Sbjct: 837 VEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQC 896 Query: 833 HGR 835 HGR Sbjct: 897 HGR 899
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.022 Identities = 9/16 (56%), Positives = 12/16 (75%) Query: 45 IIGASGSGKSLLAHAI 60 I G SG+GK L+A A+ Sbjct: 165 ITGESGTGKELVARAL 180
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 34.0 bits (77), Expect = 0.002 Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 2/87 (2%) Query: 41 IPKKDLSPSELAAAQAYWSQKQGRGARPSDY-RPTPAPGRRKAPIPDVTPNPGQGHQPD- 98 IP+ DL+P A A + P++ P PG R P PD NP D Sbjct: 310 IPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDG 369 Query: 99 NGGYHPAPPRPNDASQNKHQRDEFKGK 125 G P P D +H+++ +G+ Sbjct: 370 QPGTRPDSPAVPDRPNGRHRKERKEGE 396