>PF07201#Hypersensitivity response secretion protein HrpJ

		          Length = 293

		

		 Score = 30.2 bits (68), Expect = 0.006

		 Identities = 9/51 (17%), Positives = 24/51 (47%)

		

		Query: 138 LHAVDARVNELEELLPLLMKDKLLAKGVSHLLSSQLTRILRTHAAMSVLGH 188

		           +  V+ +VN+    +P L + + +++ +S L +S    + +  A +     

		Sbjct: 80  VSDVEEQVNQYLSKVPELEQKQNVSELLSLLSNSPNISLSQLKAYLEGKSE 130

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score =  142 bits (361), Expect = 7e-40

		 Identities = 83/387 (21%), Positives = 149/387 (38%), Gaps = 84/387 (21%)

		

		Query: 5   IGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGET------LVGQPAKRQA 58

		           + IDLGT N+ + +       + E        PS++A  QD          VG  AK+  

		Sbjct: 13  LSIDLGTANTLIYVKGQGIV-LNE--------PSVVAIRQDRAGSPKSVAAVGHDAKQML 63

		

		Query: 59  VTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAE 118

		              P N + AI+ +           +D  I  F +                     +   

		Sbjct: 64  GRTPGN-IAAIRPM-----------KDGVIADFFVTEK------------------MLQH 93

		

		Query: 119 VLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALA 178

		            +K++     +    P    ++ VP      +R+A +++ + AG     +I EP AAA+ 

		Sbjct: 94  FIKQVHS---NSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIG 150

		

		Query: 179 YGL--DKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRL 236

		            GL   + TG+    V D+GGGT ++++I ++ V           +    +GG+ FD  +

		Sbjct: 151 AGLPVSEATGS---MVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEAI 198

		

		Query: 237 INYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA----QQTDVNLPYITADATG 292

		           INY+   +    G             +  AE+ K E+ SA    +  ++ +         

		Sbjct: 199 INYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGV 245

		

		Query: 293 PKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQD-AGLSVSDIDD--VILVGGQTRMPMV 349

		           P+   +  +   LE+L E  +   +  + VAL+       SDI +  ++L GG   +  +

		Sbjct: 246 PRGFTLN-SNEILEALQEP-LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNL 303

		

		Query: 350 QKKVAEFFGKEPRKDVNPDEAVAIGAA 376

		            + + E  G       +P   VA G  

		Sbjct: 304 DRLLMEETGIPVVVAEDPLTCVARGGG 330

		

		

		>SECYTRNLCASE#Preprotein translocase SecY subunit signature.

		          Length = 437

		

		 Score = 26.6 bits (59), Expect = 0.042

		 Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 1/29 (3%)

		

		Query: 2   SKYIYILLSF-LVLFFIFFYAYISLMSKE 29

		              IYI+  F L++FF FFY  IS   +E

		Sbjct: 314 DHPIYIVTYFLLIVFFAFFYVAISFNPEE 342

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 30.6 bits (69), Expect = 0.014

		 Identities = 17/80 (21%), Positives = 27/80 (33%), Gaps = 5/80 (6%)

		

		Query: 4   RRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWVAVWQDS-YLWHVVRFSFWQ 62

		           R      GWL   +    L V  A      +W+ A      ++W+   ++          

		Sbjct: 60  RSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFVAN----TSIWRLLAFINTKPVAFTLP 115

		

		Query: 63  AFLSAQLSVVPAIFLARALY 82

		             LS   +VV   F+   LY

		Sbjct: 116 LALSIIFNVVVVTFMWSLLY 135

		

		

		>PF04605#Virulence-associated protein D (VapD)

		          Length = 125

		

		 Score = 26.0 bits (57), Expect = 0.019

		 Identities = 13/34 (38%), Positives = 20/34 (58%)

		

		Query: 1   MYNFKDKIEDYTEREFIELLGEFTNPTGDNAQLK 34

		            Y+ K+ I+D   ++F + L EFT  T  N +LK

		Sbjct: 88  QYSLKETIQDLCAKDFHQKLKEFTEKTPKNQKLK 121

		

		

		>FLGMRINGFLIF#Flagellar M-ring protein signature.

		          Length = 559

		

		 Score = 29.2 bits (65), Expect = 0.018

		 Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 22/100 (22%)

		

		Query: 110 MVKIEGGEWL----VETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDRLL- 164

		            V +E G  L    +  V  L   AV      GL P +V +          D++G  LL 

		Sbjct: 176 TVTLEPGRALDEGQISAVVHLVSSAVA-----GLPPGNVTLV---------DQSG-HLLT 220

		

		Query: 165 -SDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIG 203

		            S+    +   AQL     V   + +RI   L+ P++G G

		Sbjct: 221 QSNTSGRDLNDAQLKFANDVESRIQRRIEAILS-PIVGNG 259

		

		

		>PF00577#Outer membrane usher protein FimD

		          Length = 878

		

		 Score =  807 bits (2085), Expect = 0.0

		 Identities = 263/869 (30%), Positives = 429/869 (49%), Gaps = 40/869 (4%)

		

		Query: 12  IATFCALLYSNSALCAELVEYDHTFLMGKDASNIDLSRYTEGNPTLPGIYDVSVYVNDQP 71

		           +   CA         AE + ++  FL     +  DLSR+  G    PG Y V +Y+N+  

		Sbjct: 30  LFVACAFAAQAPLSSAE-LYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGY 88

		

		Query: 72  IMSQSIAFAVIEGKKNAQACITQKNLLQFHISSPDKNSEKAILLKRDDDLGDCLNLAEMI 131

		           + ++ + F   + ++    C+T+  L    +++   +    +          C+ L  MI

		Sbjct: 89  MATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLL------ADDACVPLTSMI 142

		

		Query: 132 PQSSIRYDVNDQRLDIDVPQAWIMKNYQNYVDPSLWENGINAAMLSYNLNGYHSESP-GR 190

		             ++ + DV  QRL++ +PQA++    + Y+ P LW+ GINA +L+YN +G   ++  G 

		Sbjct: 143 HDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGG 202

		

		Query: 191 TNDSIYAAFNGGINLGAWRLRASGNYNWMTNVHS-----DYDFQNRYLQRDLASLRSQLV 245

		            +   Y     G+N+GAWRLR +  +++ ++  S      +   N +L+RD+  LRS+L 

		Sbjct: 203 NSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLT 262

		

		Query: 246 IGESYTTGETFDSVSIRGIRLYSDSRMLPPVLASFAPIIHGVANTNAKVTVMQNGYKIYE 305

		           +G+ YT G+ FD ++ RG +L SD  MLP     FAP+IHG+A   A+VT+ QNGY IY 

		Sbjct: 263 LGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYN 322

		

		Query: 306 TTVPPGAFAIDDLSPSGYGSDLIVTIEEADGTKRTFSQPFSSVVQMLRPGVGRWDISAGQ 365

		           +TVPPG F I+D+  +G   DL VTI+EADG+ + F+ P+SSV  + R G  R+ I+AG+

		Sbjct: 323 STVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGE 382

		

		Query: 366 VLKD-SIQDEPNLFQASYYYGLNNYLTGYTGIQLTDNNYTAGLLGLGMNT-PVGAFSVDV 423

		                + Q++P  FQ++  +GL    T Y G QL D  Y A   G+G N   +GA SVD+

		Sbjct: 383 YRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLAD-RYRAFNFGIGKNMGALGALSVDM 441

		

		Query: 424 THSNVSIPDDKTYQGQSYRISWNKLFENTSTSLNIAAYRYSTQHYLGLNDALTLIDEVEH 483

		           T +N ++PDD  + GQS R  +NK    + T++ +  YRYST  Y    D         +

		Sbjct: 442 TQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYN 501

		

		Query: 484 PE-----QDLEPKSMRNYSRM---KNQVTVSINQPLKFEKKDYGSFYLSGSWSDYWASGQ 535

		            E       ++PK    Y+     + ++ +++ Q L        + YLSGS   YW +  

		Sbjct: 502 IETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL----GRTSTLYLSGSHQTYWGTSN 557

		

		Query: 536 NSTNYSIGYSNSASWGSYSISAQRSLNE-DGQTDDSIYLSFTIPIENLLGTEHRSS-GFQ 593

		               +  G + +    ++++S   + N      D  + L+  IP  + L ++ +S     

		Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617

		

		Query: 594 SIDTQLNSDFKGNNQLNISSSGYSDT-NRISYSVNTGYMMNKSSDDLSYIGGYASYESPW 652

		           S    ++ D  G         G     N +SYSV TGY      +  S      +Y   +

		Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677

		

		Query: 653 GTLSGSASASSDNSRQFSLNTDGGFVLHSGGLTFSNDSFSDSDTLAVIQAPGAKGARINY 712

		           G  +   S S D  +Q      GG + H+ G+T        +DT+ +++APGAK A++  

		Sbjct: 678 GNANIGYSHSDDI-KQLYYGVSGGVLAHANGVTLGQPL---NDTVVLVKAPGAKDAKVEN 733

		

		Query: 713 GNST-VDRWGYGVTSALSPYHENRIALDINDLENDVELKSTSTVAVPRQGAVVFADFETV 771

		                 D  GY V    + Y ENR+ALD N L ++V+L +     VP +GA+V A+F+  

		Sbjct: 734 QTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKAR 793

		

		Query: 772 QGQSAIMNIVRSDGKNIPFAADIYDEQNNIIGNVGQGGQAFVRGIEQEGNIRITWIEEGK 831

		            G   +M  +  + K +PF A +  E +   G V   GQ ++ G+   G +++ W EE  

		Sbjct: 794 VGIKLLMT-LTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEEN 852

		

		Query: 832 PVSCFAHYQQNTTSEKIAQSIILNGLRCQ 860

		              C A+YQ    S++  Q +      C+

		Sbjct: 853 A-HCVANYQLPPESQQ--QLLTQLSAECR 878

		

		

		>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature.

		          Length = 296

		

		 Score =  509 bits (1312), Expect = 0.0

		 Identities = 293/296 (98%), Positives = 294/296 (99%)

		

		Query: 2   MSGLPLISRRRLLTAMALSPLLWQMNTAHAAVIDPNRIVALEWLPVELLLALGIVPYGVA 61

		           MSGLPLISRRRLLTAMALSPLLWQMNTAHAA IDPNRIVALEWLPVELLLALGIVPYGVA

		Sbjct: 1   MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60

		

		Query: 62  DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 121

		           DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR

		Sbjct: 61  DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120

		

		Query: 122 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAHYEDFIRSMKPRFVKRGARPLLLT 181

		           GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLA YEDFIRSMKPRFVKRGARPLLLT

		Sbjct: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180

		

		Query: 182 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 241

		           TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH

		Sbjct: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240

		

		Query: 242 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRILDNAIGGKA 297

		           DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVR+LDNAIGGKA

		Sbjct: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296

		

		

		>BINARYTOXINB#Binary toxin B family signature.

		          Length = 764

		

		 Score = 34.3 bits (78), Expect = 5e-04

		 Identities = 12/55 (21%), Positives = 28/55 (50%), Gaps = 4/55 (7%)

		

		Query: 186 NDYYRKVKELRAKNQITLPVILKNERQINVFLRT----EDIDLINVINEETLLQQ 236

		            +   ++ EL A N  T+   +K   ++N+ +R      D + I V  +E+++++

		Sbjct: 589 QNIKNQLAELNATNIYTVLDKIKLNAKMNILIRDKRFHYDRNNIAVGADESVVKE 643

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 33.3 bits (76), Expect = 6e-04

		 Identities = 9/74 (12%), Positives = 29/74 (39%), Gaps = 8/74 (10%)

		

		Query: 16  LRQKDQQLSLVEETKTFLRSALARAEEKIEEDEREIEHLRA--QIEKLRRMLFGTCSEKL 73

		           L    +   ++      +R +L  +  +      E+  + +  Q+  ++   F    ++L

		Sbjct: 187 LEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQ---FE---DRL 240

		

		Query: 74  RREVEQAEALLKQR 87

		           + E +   A++  +

		Sbjct: 241 QFENQINPAIMDVQ 254

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 28.3 bits (63), Expect = 0.034

		 Identities = 8/39 (20%), Positives = 18/39 (46%), Gaps = 1/39 (2%)

		

		Query: 84  NGAQFRQLCETTDWVDAGE-NVLLFGASGLGKSHLAAAI 121

		             A  +++      +   +  +++ G SG GK  +A A+

		Sbjct: 142 RSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 32.7 bits (74), Expect = 0.002

		 Identities = 12/22 (54%), Positives = 13/22 (59%)

		

		Query: 32  VTVLLGPNGCGKSTLLRALAGL 53

		             VL G  G GKSTL+  L GL

		Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  132 bits (333), Expect = 1e-39

		 Identities = 77/262 (29%), Positives = 131/262 (50%), Gaps = 14/262 (5%)

		

		Query: 4   INMFSLKGKNALVTGASYGIGFEIAKALSNAGATIIFNDVIEENIKKGLAAYKENNINAH 63

		           +N   ++GK A +TGA+ GIG  +A+ L++ GA I   D   E ++K +++ K    +A 

		Sbjct: 1   MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60

		

		Query: 64  GYLFDITDEQSVKENIKKIESDVGIIDILVNNAGIIQRKPMLETTAADYRKIIDIDLTGQ 123

		            +  D+ D  ++ E   +IE ++G IDILVN AG+++   +   +  ++     ++ TG 

		Sbjct: 61  AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120

		

		Query: 124 FIMAKAVLPSMIKKGHGKIINICSMMSELGRETVVGYASAKGGLKMLTKNICSEFGEKNI 183

		           F  +++V   M+ +  G I+ + S  + + R ++  YAS+K    M TK +  E  E NI

		Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180

		

		Query: 184 QCNGIGPGYIAT--------PQTAPLREIQPDGSRHPFDQFIISKTPAGRWGKPDDLAGA 235

		           +CN + PG   T         +    + I+        + F     P  +  KP D+A A

		Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSL-----ETFKTG-IPLKKLAKPSDIADA 234

		

		Query: 236 AIFLASDASNFINGHILYVDGG 257

		            +FL S  +  I  H L VDGG

		Sbjct: 235 VLFLVSGQAGHITMHNLCVDGG 256

		

		

		>PF05860#haemagglutination activity domain.

		          Length = 117

		

		 Score = 74.1 bits (182), Expect = 2e-17

		 Identities = 25/139 (17%), Positives = 44/139 (31%), Gaps = 26/139 (18%)

		

		Query: 32  AVITPQNGA---GMDKAANGVPVVNIATPNGAGISHNRFTDYNVGKEGLILNNATGKLNP 88

		           A ITP                 ++   T  G+ + H+ F +++V   G    N       

		Sbjct: 1   AQITPDTTLPINSNITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNPT---- 55

		

		Query: 89  TQLGGLIQNNPNLKAGGEAKGIINEVTGGKRSLLQGYTEVAGKAANVMVANPYGITCDGC 148

		                              + II+ VTGG  S + G       A N+ + NP GI     

		Sbjct: 56  -----------------NIQNIISRVTGGSVSNIDGLIRANATA-NLFLINPNGIIFGQN 97

		

		Query: 149 GFINTPHATLTTGKPVMNA 167

		             ++   + + +    +  

		Sbjct: 98  ARLDIGGSFVGSTANRLKF 116

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score =  738 bits (1906), Expect = 0.0

		 Identities = 260/862 (30%), Positives = 401/862 (46%), Gaps = 116/862 (13%)

		

		Query: 53  SQAGIVRSDIAYQIYRDFAENKGLFVPGATDIPVYDKDGKLVGRL--DKAPMADFSSVSS 110

		           ++A +VR D+ YQI+RDFAENKG F  GAT++ V DK+ K +G    +  PM DFS V  

		Sbjct: 23  TEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNKDLGTALPNGIPMIDFSVVDV 82

		

		Query: 111 N-GVATLVSPQYIVSVKH-NGGYQSVSFGN------------------GKNTYSLVDRNN 150

		           +  +ATL++PQY+V VKH + G   + FGN                   +N Y  V++N 

		Sbjct: 83  DKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKAHRDVSSEENRYFSVEKNE 142

		

		Query: 151 HSSV-----------------DFHAPRLNKLVTEVIPSAITSEGTKANAYKDTERYTAFY 193

		           + +                  D++ PRL+K VTEV P   ++  + A  Y D  +Y AF 

		Sbjct: 143 YPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDAGTYNDQNKYPAFV 202

		

		Query: 194 RVGSGTQYTKDKDGNLVKVAGGYAFKTGGTTGVPLISDATIVSNPGQTYNPVNG------ 247

		           R+GSG+Q+   K  N   +   +         V       I   P +  +  NG      

		Sbjct: 203 RLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDAYTYGIAGTPYKVNHENNGLIGFGN 262

		

		Query: 248 ---------------PLPDYGAPGDSGSPLFAYDEQQKKWVIVAVLRAYAGINGAT-NWW 291

		                          PL +Y   GDSGSPLF YD ++ KW+ +     +AG N  +   W

		Sbjct: 263 SKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYDFWAGYNKKSWQEW 322

		

		Query: 292 NVIPTDYLNQVMQDDFDAPVDFVSGLPPLNWTYDKTSGTGTLSQGSKNWTMHGQKDNDLN 351

		           N+  + +   V+  D  +    +      +W+ +  + T T  + S N  +   KD   N

		Sbjct: 323 NIYKSQFTKDVLNKD--SAGSLIGSKTDYSWSSNGKTSTITGGEKSLNVDLADGKDKP-N 379

		

		Query: 352 AGKNLVFSGQNGAIVLKDSVTQGAGYLEFKDSYTVSAES-GKTWTGAGIITDKGTNVTWK 410

		            GK++ F G +G + L +++ QGAG L F+  Y V   S   TW GAG+   +G  VTWK

		Sbjct: 380 HGKSVTFEG-SGTLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWKGAGVSVAEGKTVTWK 438

		

		Query: 411 VNGVAGDNLHKLGEGTLTINGTGVNPGGLKTGDGTVVLNQQADTAGNVQAFSSVNLASGR 470

		           V+    D L K+G+GTL + GTG N G LK GDGTV+L QQ + +G   AF+SV + SGR

		Sbjct: 439 VHNPQYDRLAKIGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGSGQ-HAFASVGIVSGR 497

		

		Query: 471 PTVVLGDARQVNPDNISWGYRGGKLDLNGNAVTFTRLQAADYGAVITN-NAQQKSRLLLD 529

		            T+VL D +QV+P++I +G+RGG+LDLNGN++TF  ++  D GA + N N    S + + 

		Sbjct: 498 STLVLNDDKQVDPNSIYFGFRGGRLDLNGNSLTFDHIRNIDDGARLVNHNMTNASNITIT 557

		

		Query: 530 LKAQDT--------NVSVP-IGSISPFGGTGTPGNLYSMILNGQTRFYILKSASYGNTLW 580

		            ++  T        N+  P   +   F      G LY + L   T + + K AS  + L 

		Sbjct: 558 GESLITDPNTITPYNIDAPDEDNPYAFRRIKDGGQLY-LNLENYTYYALRKGASTRSELP 616

		

		Query: 581 GNSLNDPAQWEFVGTDKNKAVQTVKDRILAGRAKQPVIF----HGQLTGNMDVTIPQLPG 636

		            NS      W ++G   ++A + V + I   R      +     G+  GN++VT      

		Sbjct: 617 KNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSE 676

		

		Query: 637 GRKVILDGSVNLPEGTLSEDSGTLIFQGHPVIHA-SVSGSAPVSLN-----------QKD 684

		             + +L G  NL  G L+ + GTL   G P  HA  ++G +    +           + D

		Sbjct: 677 QNRFLLTGGTNL-NGDLTVEKGTLFLSGRPTPHARDIAGISSTKKDPHFAENNEVVVEDD 735

		

		Query: 685 WENRQFIMKTLSLK-DADFHLSRN-ASLNSDIKSDNS---HITLGSDRVFVDKNDGTGNY 739

		           W NR F   T+++  +A  +  RN A++ S+I + N    HI   +      ++D TG  

		Sbjct: 736 WINRNFKATTMNVTGNASLYSGRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGY- 794

		

		Query: 740 VILEEGTSVPDTVNDR-------SQYEGNITLDHNSTLDIGSR--FTGGIEAYDSAVSIT 790

		                 T   D ++D+       +   GN+ L  ++   +G    F       +S V +T

		Sbjct: 795 -----VTCTTDKLSDKALNSFNPTNLRGNVNLTESANFVLGKANLFGTIQSRGNSQVRLT 849

		

		Query: 791 SPDVLLTAPGAFAGSSLTVHDG 812

		             +      G      L + +G

		Sbjct: 850 E-NSHWHLTGNSDVHQLDLANG 870

		

		

		

		 Score = 80.1 bits (197), Expect = 4e-17

		 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 18/154 (11%)

		

		Query: 864  DNATLEITRGAHASGDIHASAASTVTIGSDTPAELASAETTASAFAG--------SLLEG 915

		            + A + I      +  + +     VT  +D  ++ A      +   G        + + G

		Sbjct: 771  NKAQVHIGYKTGDTVCVRSDYTGYVTCTTDKLSDKALNSFNPTNLRGNVNLTESANFVLG 830

		

		Query: 916  YNAAFNGAITGGRADVSM-HNALWTLGGDSAIHTLTVRNSRI------SSEGDRTFRTLT 968

		                F    + G + V +  N+ W L G+S +H L + N  I      +S     + TLT

		Sbjct: 831  KANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSADNSNNVTKYNTLT 890

		

		Query: 969  VNKLDATGSDFVLRTDLKN--ADKINVTEKATGS 1000

		            VN L   GS + L TDL N   DK+ VT+ ATG+

		Sbjct: 891  VNSLSGNGSFYYL-TDLSNKQGDKVVVTKSATGN 923

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score =  234 bits (598), Expect = 2e-74

		 Identities = 88/430 (20%), Positives = 179/430 (41%), Gaps = 64/430 (14%)

		

		Query: 45  LMVIFLLVLVVTFVIWAWNSPLDEVTRGQGSIIPGSREQVIQTLDPGILKTLEVREGDIV 104

		           L+  F++  +V   I +    ++ V    G +    R + I+ ++  I+K + V+EG+ V

		Sbjct: 59  LVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESV 118

		

		Query: 105 EKGQVLLTLDDTRSSAMLRESEARVNNLEAVRARLRAEAYS------ESLTFPDD-VPAD 157

		            KG VLL L    + A   ++++ +      + R +  + S        L  PD+    +

		Sbjct: 119 RKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQN 178

		

		Query: 158 LRERESTVYR--------LRKTELAQS-----------------IAGLKQSKALLDKEIA 192

		           + E E               + +  Q                  I   +    +    + 

		Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLD 238

		

		Query: 193 MTRPIVREGAMSEVELLRMQRQSAEL---------------------QLQMDEKQNKYLT 231

		               ++ + A+++  +L  + +  E                      + +       +  

		Sbjct: 239 DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN 298

		

		Query: 232 EAGAELVKTEAELAQAKENMAGRADPVERSRIRAPLRGIVKNIRVNTLGGVVSAGQDIME 291

		           E   +L +T   +      +A   +  + S IRAP+   V+ ++V+T GGVV+  + +M 

		Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358

		

		Query: 292 IIPLEDQLLIEAYINPRDVAYVRTGMPALVKLTAYDYAIYGGLDGVVTLVSPDTLRDQKR 351

		           I+P +D L + A +  +D+ ++  G  A++K+ A+ Y  YG L G V  ++ D + DQ+ 

		Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQR- 417

		

		Query: 352 PGDLKLDPNEAYYRVLVTTSNNYLTDRNGKILPVIPGMIASVDIKTGQKSVFQYLIKPIT 411

		                       + V+++   N L+    K +P+  GM  + +IKTG +SV  YL+ P+ 

		Sbjct: 418 --------LGLVFNVIISIEENCLS-TGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLE 468

		

		Query: 412 -RMKQALQER 420

		             + ++L+ER

		Sbjct: 469 ESVTESLRER 478

		

		

		>CABNDNGRPT#NodO calcium binding signature.

		          Length = 479

		

		 Score = 47.7 bits (113), Expect = 3e-07

		 Identities = 32/192 (16%), Positives = 58/192 (30%), Gaps = 25/192 (13%)

		

		Query: 1327 NNIDTATDVNTVTIYGSVSGEILGGYGSDNITVTKNLTGNISVGDNADTLTAGWIYGGST 1386

		             N+ T T  +      +   +      S    +      ++      DT           

		Sbjct: 260  ANMTTRTGDSVYGFNSNTDRDFYTATDSSKALI-----FSVWDAGGTDTFDFSGYSNNQR 314

		

		Query: 1387 VSMGDGNDT--------VTITDGAYNTTISLGAGDDVFDATSGVMGDSAYATVVNGEDGN 1438

		            +++ +G+ +        V+I  G        G+G+D+    S          ++ G  GN

		Sbjct: 315  INLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSA-------DNILQGGAGN 367

		

		Query: 1439 DTFKLGTIAKNLTIDAGAGDDIVVLTKDYDSTSSGN---QGYINGGEGSDTLVLTGTISV 1495

		            D    G  A   T+  GAG D  V     DST +       +  G +  D         +

		Sbjct: 368  DVLYGG--AGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSAFRNEGQL 425

		

		Query: 1496 NLAAGKNEGIAG 1507

		            +    +  G   

		Sbjct: 426  SFVQDQFTGKGQ 437

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score =  614 bits (1585), Expect = 0.0

		 Identities = 267/886 (30%), Positives = 407/886 (45%), Gaps = 123/886 (13%)

		

		Query: 42  SLALSALLPTVAGASTVGGNNPYQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DK 99

		           +L ++  L     A+ V  +  YQ +RDFAENKG+F  GATN+ + +   + +G    + 

		Sbjct: 12  ALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNKDLGTALPNG 71

		

		Query: 100 APMVDFSSVNVSSNPGVATLINPQYIASVKH-NKGYQSVSFG------------------ 140

		            PM+DFS V    +  +ATLINPQY+  VKH + G   + FG                  

		Sbjct: 72  IPMIDFSVV--DVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKAHRDVS 129

		

		Query: 141 DGQNSYHIVDRNEHSSS-----------------DLHTPRLDKLVTEVAPATVTSSST-- 181

		             +N Y  V++NE+ +                  D + PRLDK VTEVAP   +++S+  

		Sbjct: 130 SEENRYFSVEKNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDA 189

		

		Query: 182 ADILNPSKYSAFYRAGSGSQYIQDSQGKRHWVTGGYGYLTGGILPTSFFYH--------- 232

		               + +KY AF R GSGSQ+I         +   +      +      Y          

		Sbjct: 190 GTYNDQNKYPAFVRLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDAYTYGIAGTPYK 249

		

		Query: 233 --GSDGIQLYMGGNIHDHSI---------LPSFGEAGDSGSPLFGWNTAKGQWELVGVYS 281

		               +   +  G +  +HS          L ++   GDSGSPLF ++  KG+W  +G Y 

		Sbjct: 250 VNHENNGLIGFGNSKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYD 309

		

		Query: 282 ---GVGGGTNLIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPLQWKFDSSTGTGSLKQGS 338

		              G    +   +++    F   + ++D+   +  +        + + S+  T ++  G 

		Sbjct: 310 FWAGYNKKSWQEWNIYKSQFTKDVLNKDSAGSLIGSK-----TDYSWSSNGKTSTITGGE 364

		

		Query: 339 DEYAMHGQKGSDL-NAGKNLTFLGHNGQIDLENSVTQGAGSLTFTDDYTVT-TSNGSTWT 396

		               +    G D  N GK++TF G +G + L N++ QGAG L F  DY V  TS+ +TW 

		Sbjct: 365 KSLNVDLADGKDKPNHGKSVTFEG-SGTLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWK 423

		

		Query: 397 GAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSS 456

		           GAG+ V +  +V W+V+  + D L KIG+GTL+V+GTG N+G LKVGDGTV+L QQ + S

		Sbjct: 424 GAGVSVAEGKTVTWKVHNPQYDRLAKIGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGS 483

		

		Query: 457 GHVQAFSSVNIASGRPTVVLADNQQVNPDNISWGYRGGVLDVNGNDLTFHKLNAADYGAT 516

		           G   AF+SV I SGR T+VL D++QV+P++I +G+RGG LD+NGN LTF  +   D GA 

		Sbjct: 484 GQ-HAFASVGIVSGRSTLVLNDDKQVDPNSIYFGFRGGRLDLNGNSLTFDHIRNIDDGAR 542

		

		Query: 517 LGNS-SDKTANITLD---YQTRPADVKV---------NEWSSSNRGTVGSLYIYNNPYTH 563

		           L N      +NIT+      T P  +           N ++       G LY+    YT 

		Sbjct: 543 LVNHNMTNASNITITGESLITDPNTITPYNIDAPDEDNPYAFRRIKDGGQLYLNLENYT- 601

		

		Query: 564 TVDYFILK--TSSYGWFP-TGQVSNEHWEYVGHDQNSAQALLANRINNK------GYLY- 613

		              Y+ L+   S+    P     SNE+W Y+G   + A+  + N INN+      GY   

		Sbjct: 602 ---YYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGE 658

		

		Query: 614 -HGKLLGNINFSNKATPGTTGALVMDGSANMSGTFTQENGRLTIQGHPVIHASTSQSIAN 672

		             GK  GN+N + K         ++ G  N++G  T E G L + G P  HA   + IA 

		Sbjct: 659 EEGKNNGNLNVTFKGKSE-QNRFLLTGGTNLNGDLTVEKGTLFLSGRPTPHA---RDIAG 714

		

		Query: 673 TVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLK-DTDFGLGRN-ATLNTTIQADNSS- 729

		             S+  D           +DDW NR F   ++ +  +     GRN A + + I A N + 

		Sbjct: 715 ISSTKKDPHFAENNEVVVEDDWINRNFKATTMNVTGNASLYSGRNVANITSNITASNKAQ 774

		

		Query: 730 ----VTLGDSRVFIDKKDGQGTAFTLEEGTSVATKDADKSVFNGTVNLDNQS--VLNINE 783

		                  GD+        G  T  T ++ +  A    + +   G VNL   +  VL    

		Sbjct: 775 VHIGYKTGDTVCVRSDYTGYVTC-TTDKLSDKALNSFNPTNLRGNVNLTESANFVLGKAN 833

		

		Query: 784 IFNGGIQANNSTVNISSDS-------AVLENSTLTSTALNLNKGAN 822

		           +F       NS V ++ +S       + +    L +  ++LN   N

		Sbjct: 834 LFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSADN 879

		

		

		

		 Score = 53.9 bits (129), Expect = 5e-09

		 Identities = 65/329 (19%), Positives = 121/329 (36%), Gaps = 54/329 (16%)

		

		Query: 760  KDADKSVFNGTVNLDNQSVLNINEIFNGGIQANNSTVNISSDSAVLENSTLTSTALNLNK 819

		            K +D++  N   +++N+ +   N  F      NN  +N++      +N  L +   NLN 

		Sbjct: 631  KTSDEAKRNVMNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSEQNRFLLTGGTNLNG 690

		

		Query: 820  GANVLASQSFVSDGPVNISDATLSLNSRPDEVSHTLLPVYDYAGSW----------NLKG 869

		               V     F+S  P   +     ++S   +              W          N+ G

		Sbjct: 691  DLTVEKGTLFLSGRPTPHARDIAGISSTKKDPHFAENNEVVVEDDWINRNFKATTMNVTG 750

		

		Query: 870  DDARLNVGPYSMLSGNINVQDKGTVTLG--------------GEGELSPDLTLQNQMLYS 915

		            + +  +    + ++ NI   +K  V +G              G    + D  L ++ L S

		Sbjct: 751  NASLYSGRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTD-KLSDKALNS 809

		

		Query: 916  LFN-----------------GYRNTWSGSLNAPDATVSMT-DTQWSMNGNSTAGNMKLNR 957

		                                G  N +    +  ++ V +T ++ W + GNS    + L  

		Sbjct: 810  FNPTNLRGNVNLTESANFVLGKANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLAN 869

		

		Query: 958  TIVGFNGGTSS-----FTTLTTDNLDAVQSAFVMRTDL--NKADKLVINKSATGHDNSIW 1010

		              +  N   +S     + TLT ++L     +F   TDL   + DK+V+ KSATG+     

		Sbjct: 870  GHIHLNSADNSNNVTKYNTLTVNSLSG-NGSFYYLTDLSNKQGDKVVVTKSATGNFTLQV 928

		

		Query: 1011 VNFLKKPSDKDTLDIPLVSAPEATADNLF 1039

		             +   +P+     ++ L  A +A  D+L 

		Sbjct: 929  ADKTGEPNHN---ELTLFDASKAQRDHLN 954

		

		

		>PF00577#Outer membrane usher protein FimD

		          Length = 878

		

		 Score = 62.6 bits (152), Expect = 5e-12

		 Identities = 29/247 (11%), Positives = 73/247 (29%), Gaps = 23/247 (9%)

		

		Query: 487 TLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQSVYSGTFGSLGLRAGIQRYNNGDSS 546

		            L +     +  T  +S    + Y       + +Q+  +  F  +          N    

		Sbjct: 530 QLTVTQQLGRTSTLYLSG-SHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQK 588

		

		Query: 547 ANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGT------------IRTV 594

		               + +AL++++P  +W  +    Q  +  A+ S     +                  +

		Sbjct: 589 -GRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNL 647

		

		Query: 595 GANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYINTNLTANGSVGWQGK 654

		             ++    +G    +   +G A   +   Y +  +   S +D         +G V     

		Sbjct: 648 SYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGY-SHSDDIKQLYYGVSGGVLAHAN 706

		

		Query: 655 NIAASGRTDGNAGVIFDTGLEN---DGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQ 711

		            +      +    ++   G ++   + Q   + + R     G       + Y    V L 

		Sbjct: 707 GVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR-----GYAVLPYATEYRENRVALD 761

		

		Query: 712 NSKNSLD 718

		            +  + +

		Sbjct: 762 TNTLADN 768

		

		

		>INTIMIN#Intimin signature.

		          Length = 939

		

		 Score =  548 bits (1413), Expect = e-178

		 Identities = 233/832 (28%), Positives = 355/832 (42%), Gaps = 78/832 (9%)

		

		Query: 41  PVMAARAQHAVQPRLSMENTTVTADNNVEKNVASLAANAGTFLSSQPDS-----DATRNF 95

		           P++AA        +L+  +  VT  N  +    + AA     L SQ  S     D  ++ 

		Sbjct: 131 PLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSRSLNGDYAKDT 190

		

		Query: 96  ITGMATAKANQEIQEWLGKYGTARVKLNVDKKFSLKDSSLEMLYPIYDTPTNMLFTQGAI 155

		             G+A  +A+ ++Q WL  YGTA V L     F    SSL+ L P YD+   + F Q   

		Sbjct: 191 ALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD--GSSLDFLLPFYDSEKMLAFGQVGA 248

		

		Query: 156 HRTDDRTQSNIGFGWRHFSENDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGY 215

		              D R  +N+G G R F   + M G N FID D S  +TR+G+G EYWRDY K S NGY

		Sbjct: 249 RYIDSRFTANLGAGQRFF-LPENMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGY 307

		

		Query: 216 IRASGWKKSPDVEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQ 275

		            R SGW +S + +DY ERPANG+DIR  GYLP++P LGA LMYEQYYGD V LF  DK Q

		Sbjct: 308 FRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQ 367

		

		Query: 276 KDPHAITAEVNYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLEKQLDTDSIRER 335

		            +P A T  VNYTP+PL+T+   ++ G   END  + ++  Y+  +P  +Q++   + E 

		Sbjct: 368 SNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNEL 427

		

		Query: 336 RMLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTVSLGLVVSKATHGLKNVQ 395

		           R L+GSRYDLV+RNNNI+LEY+K +++ + +P  I G    T  + L+V K+ +GL  + 

		Sbjct: 428 RTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTERSTQKIQLIV-KSKYGLDRIV 486

		

		Query: 396 WEAPSLLAAGGKITGQG----NQWQVTLPAYQAGKDNYYAISAIAYDNKGNASKRVQTEV 451

		           W+  +L + GG+I   G      +Q  LPAY  G  N Y ++A AYD  GN+S  V   +

		Sbjct: 487 WDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNVLLTI 546

		

		Query: 452 VISGAGMSADRTALTLDGQSRIQMLANGNEQKPLVLSLR----DAEGQPVTGMKDQIKTE 507

		            +   G   D+  +T     +    A+G E      +++         PV+         

		Sbjct: 547 TVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVS--------- 597

		

		Query: 508 LTFKPAGNIVTRTLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDDMSK 567

		                  NIV+ T   + + A           +G       +    G+  ++    +M+ 

		Sbjct: 598 ------FNIVSGTAVLSANSAN-------TNGSGKATVTLKSDK-PGQVVVSAKTAEMTS 643

		

		Query: 568 TVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLRLVP 627

		            + A     +     S           VA+GQ A T T+  V     PV+ +        

		Sbjct: 644 ALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVK-VMKGDKPVSNQEVTF---- 698

		

		Query: 628 QDTNGVTVGAIS--EIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP--- 682

		             T    +   +      G    T++ST  G  +V A      +      ++F       

		Sbjct: 699 -TTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTID 757

		

		Query: 683 ----------LDAAHSSITLNPDK---PVVGGTVTAIWTAKDANDNPVTGLNPDAPSLSG 729

		                     +     ++ L   +      GG     W + +     V   +    +L  

		Sbjct: 758 DGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDA-SSGQVTLKE 816

		

		Query: 730 AAAAGSTASGWTDNGDGTWTAQISLGTTAGELDVMPKLNGQDAAANAAKVTVVADALSSN 789

		                 +    +DN   T+T       T   L V                      L S+

		Sbjct: 817 KGTTTISVIS-SDNQTATYTIA-----TPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSS 870

		

		Query: 790 QSKV-------SVAEDHVKAGESTTVTLVAKDAHGNAISGLSLSASLTGTAS 834

		           Q+++         A  +     S T+    +    +A SG++ +  L     

		Sbjct: 871 QNELENVFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVASTYDLVKQNP 922

		

		

		

		 Score = 74.0 bits (181), Expect = 4e-15

		 Identities = 74/345 (21%), Positives = 113/345 (32%), Gaps = 42/345 (12%)

		

		Query: 905  KTTTELTFTVK----DAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVSTL 960

		                  T TVK         PV+       + SG A       SA +    G+G    TL

		Sbjct: 575  TEAITYTATVKKNGVAQANVPVSFN-----IVSGTAV-----LSANSANTNGSGKATVTL 624

		

		Query: 961  TLGSAAGQLSVMPRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITL 1020

		                    +         +A+    V+ V  D +KA I ++       +ANGQ A  IT 

		Sbjct: 625  KSDKPGQVVVSAKTAEMTSALNANAVIFV--DQTKASITEIKADKTTAVANGQDA--ITY 680

		

		Query: 1021 TV-VDSYGNPLQGQEVTLTLPQGVTSKTGNTVTTNAAGKVDIELMSTVAGELEIEASVKN 1079

		            TV V     P+  QEVT T   G  S +  T  T+  G   + L ST  G+  + A V +

		Sbjct: 681  TVKVMKGDKPVSNQEVTFTTTLGKLSNS--TEKTDTNGYAKVTLTSTTPGKSLVSARVSD 738

		

		Query: 1080 SQKTVKVKFKADFSTGQASLEVDAA-AQKVANGKDAFTLTATVK-DQYGNLLPGAVVVFN 1137

		                VK      F     +L +D    + V  G      T  ++  Q      G    + 

		Sbjct: 739  VAVDVKAPEVEFF----TTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYT 794

		

		Query: 1138 LPRGVKPLADGNIMVNADKEGKAELKVVSVTAGTYEITASAGNDQPSNAQSVTFVADKTT 1197

		                    A+  I       G+  LK      GT  I+  + ++Q       T+      

		Sbjct: 795  W-----RSANPAIASVDASSGQVTLK----EKGTTTISVISSDNQT-----ATYTIATPN 840

		

		Query: 1198 ATISSIEVIGNRAVADGKTKQTYKVTVTDANNNLLKDSEVTLTAS 1242

		            + I    +       D             ++ N L++      A+

		Sbjct: 841  SLI-VPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAA 884

		

		

		

		 Score = 54.7 bits (131), Expect = 2e-09

		 Identities = 46/249 (18%), Positives = 82/249 (32%), Gaps = 24/249 (9%)

		

		Query: 1168 TAGTYEITASA----GNDQPSNAQSVTFVADKTTAT---ISSIEVIGNRAVADGKTKQTY 1220

		             +  Y++TA A    GN   +   ++T +++        ++        A ADG    TY

		Sbjct: 521  GSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITY 580

		

		Query: 1221 KVTVTDANNNLLKDSEVTLTASPENLVLTPNGTATTNEQGQAIFTATTTVAATYTLTAKV 1280

		              TV                 S     +    +A TN  G+A  T  +       ++AK 

		Sbjct: 581  TATVKKNGVAQANVPVSFNIVS--GTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAK- 637

		

		Query: 1281 EQADGQESTKTAESKFVADDKNAVLAASPERVDSLVADGKTTATLTVTLMSGVNPVGGTM 1340

		              A+   +       FV   K ++     ++  + VA+G+   T TV +M G  PV    

		Sbjct: 638  -TAEMTSALNANAVIFVDQTKASITEIKADK-TTAVANGQDAITYTVKVMKGDKPVSNQE 695

		

		Query: 1341 WVDIEA--PEGVTEADYQFLPSKNDHFASGKITRTFSTNKPGTYTFTFNSLTYGGYEMKP 1398

		                        +         K D   +G    T ++  PG    +   ++    ++K 

		Sbjct: 696  VTFTTTLGKLSNSTE-------KTD--TNGYAKVTLTSTTPGKSLVS-ARVSDVAVDVKA 745

		

		Query: 1399 VTVTINAVP 1407

		              V      

		Sbjct: 746  PEVEFFTTL 754

		

		

		

		 Score = 47.0 bits (111), Expect = 5e-07

		 Identities = 56/368 (15%), Positives = 104/368 (28%), Gaps = 56/368 (15%)

		

		Query: 779  VTVVADALSSNQSKV---SVAEDHVKAGESTTVTLVA------KDAHGNAISGLSLSASL 829

		            +TV+++    +Q  V   +  +   KA  +  +T  A             +S   +S   

		Sbjct: 546  ITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSG-- 603

		

		Query: 830  TGTASEGATVSSWTEKGDGSYVAT--LTTGGKTGELRVMPLFNGQPAATEAAQLTVIAGE 887

		                   A +S+ +   +GS  AT  L +      +          A    A   +   +

		Sbjct: 604  ------TAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALN--ANAVIFVDQ 655

		

		Query: 888  MSSANSTLVADNKTPTVKTTTELTFTVKDAY-GNPVTGLKPDAPVFSGAASTGSERPSAG 946

		              ++ + + AD  T        +T+TVK      PV+  +          +T   + S  

		Sbjct: 656  TKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEV-------TFTTTLGKLSNS 708

		

		Query: 947  NWTEKGNGVYVSTLTLGSAAGQLSVMPRVNGQN-AVAQPLVLNVAG---DASKAEIRDMT 1002

		                  NG    TLT  +  G+  V  RV+     V  P V        D    EI    

		Sbjct: 709  TEKTDTNGYAKVTLT-STTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEI---- 763

		

		Query: 1003 VKVNNQLANGQSANQITLTV-VDSYGNPLQGQEVTLTLPQGVTSKTGNTVTTNAAGKVDI 1061

		                  +  G      T+ +          G     T     ++         ++G+V +

		Sbjct: 764  ------VGTGVKGKLPTVWLQYGQVNLKASGGNGKYTW---RSANPAIASVDASSGQVTL 814

		

		Query: 1062 ELMSTVAGELEIEASVKNSQKTVKVKFKADFSTGQASLEVDAAAQKVANGKDAFTLTATV 1121

		            +      G   I     ++Q      +            +        +  +        

		Sbjct: 815  K----EKGTTTISVISSDNQ---TATYTIATPNSLIVPNMSKRVT-YNDAVNTCKNFGGK 866

		

		Query: 1122 KDQYGNLL 1129

		                 N L

		Sbjct: 867  LPSSQNEL 874

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 28.4 bits (63), Expect = 0.027

		 Identities = 12/42 (28%), Positives = 19/42 (45%)

		

		Query: 14 RQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN 55

		          RQ IL   L           S+ +IA+ +G +R  I   F++

		Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKD 54

		

		

		>PRTACTNFAMLY#Pertactin virulence factor family signature.

		          Length = 910

		

		 Score =  122 bits (307), Expect = 1e-30

		 Identities = 112/509 (22%), Positives = 187/509 (36%), Gaps = 73/509 (14%)

		

		Query: 330 LDINLSDSSVWKGKVSGAGDASVSLQNGSVWNVTGSSTVDALAVKDSTVNITKATVNTGT 389

		           LD+ L+  + W G        S+S+ N   W +T +S V AL +        +     G 

		Sbjct: 413 LDVALASQARWTGATRAVD--SLSIDNA-TWVMTDNSNVGALRLASDGSVDFQQPAEAGR 469

		

		Query: 390 FA-------SQNGTLI----VDASSENTLDISGKASGDLRVY---------SAGSLDLIN 429

		           F        + +G        D    + L +   ASG  R++         SA +L L+ 

		Sbjct: 470 FKVLTVNTLAGSGLFRMNVFADLGLSDKLVVMQDASGQHRLWVRNSGSEPASANTLLLVQ 529

		

		Query: 430 EQ----TAFISTGKDSTLKATGTTEGGLYQYDLTQGADGNFYFVKNTHK----------- 474

		                   F    KD      G  + G Y+Y L    +G +  V                

		Sbjct: 530 TPLGSAATFTLANKD------GKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGP 583

		

		Query: 475 -----------------------ASNASSVIQAMA-AAPANVANLQADTLSARQDAVRLS 510

		                                  ++ A++ +        + +   +++ LS R   +RL+

		Sbjct: 584 QPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLN 643

		

		Query: 511 ENDKGGVWIQYFGGKQKHTTAGNASYDLDVNGVMLGGDTRFMTEDGSWLAGVAMSSAKGD 570

		             D GG W + F  +Q+        +D  V G  LG D       G W  G      +GD

		Sbjct: 644 P-DAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGD 702

		

		Query: 571 MT-TMQSKGDTEGYSFHAYLSRQYNNGIFIDTAAQFGHYSNTADVRLMNGGGTIKADFNT 629

		              T    G T+      Y +   ++G ++D   +     N   V   +G   +K  + T

		Sbjct: 703 RGFTGDGGGHTDSVHVGGYATYIADSGFYLDATLRASRLENDFKVAGSDGY-AVKGKYRT 761

		

		Query: 630 NGFGAMVKGGYTWKDGNGLFIQPYAKLSALTLEGVDYQL-NGVDVHSDSYNSVLGEAGTR 688

		           +G GA ++ G  +   +G F++P A+L+     G  Y+  NG+ V  +  +SVLG  G  

		Sbjct: 762 HGVGASLEAGRRFTHADGWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLE 821

		

		Query: 689 VGYDFAVGNA-TVKPYLNLAALNEFSDGNKVRLGDESVNASIDGAAFRVGAGVQADITKN 747

		           VG    +     V+PY+  + L EF     V     +    + G    +G G+ A + + 

		Sbjct: 822 VGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRG 881

		

		Query: 748 MGAYASLDYTKGDDIENPLQGVVGINVTW 776

		              YAS +Y+KG  +  P     G   +W

		Sbjct: 882 HSLYASYEYSKGPKLAMPWTFHAGYRYSW 910

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 62.7 bits (152), Expect = 2e-14

		 Identities = 31/172 (18%), Positives = 58/172 (33%), Gaps = 15/172 (8%)

		

		Query: 16  RRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLR 75

		            R+ ++D  L   ++ G+   ++ +IA+ AGV+ G I  +F+DK+ L         S + 

		Sbjct: 12  TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71

		

		Query: 76  DAVLNRLHALPQGSAERRLQAIVGGNFDETQVSSAAMKAWLAFWASSMHQP-------ML 128

		           +  L      P       L+ I+    + T V+    +  +                   

		Sbjct: 72  ELELEYQAKFPGDPLS-VLREILIHVLEST-VTEERRRLLMEIIFHKCEFVGEMAVVQQA 129

		

		Query: 129 YRLQQVSSRRLLSNLVSEFRRE---LPRQQAQEAGYGLAALIDGL---WLRA 174

		            R   + S   +   +               + A   +   I GL   WL A

		Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181

		

		

		>ACETATEKNASE#Acetate kinase family signature.

		          Length = 400

		

		 Score = 29.4 bits (66), Expect = 0.020

		 Identities = 17/69 (24%), Positives = 29/69 (42%), Gaps = 10/69 (14%)

		

		Query: 233 FISGTGFATDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVVNILDP- 291

		               +G ++D+R L   A          +  D  A+LAL  +  R+ K++      +   

		Sbjct: 273 VYGISGISSDFRDLEDAAF---------KNGDKRAQLALNVFAYRVKKTIGSYAAAMGGV 323

		

		Query: 292 DVIVLGGGM 300

		           DVIV   G+

		Sbjct: 324 DVIVFTAGI 332

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 51.4 bits (123), Expect = 3e-09

		 Identities = 73/356 (20%), Positives = 126/356 (35%), Gaps = 35/356 (9%)

		

		Query: 33  ILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGH---MISYYALGVVVGAPIIALF 89

		           + ++AL   G+G+    IM VL  L  ++  S     H   +++ YAL     AP++   

		Sbjct: 11  LSTVALDAVGIGL----IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66

		

		Query: 90  SSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIK 149

		           S R+  + +LL  +A   +  A+   +    +L IGR+V+G         GA +    I 

		Sbjct: 67  SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD--IT 124

		

		Query: 150 PGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDI 209

		            G   A   G +S      ++  P+   L   FS    F   A  N     +  F +P+ 

		Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184

		

		Query: 210 RDEAKGKLREQ----------FHFLRSPAPWLI--FAATMFGNAGVFAWFSYVKPYMMFI 257

		               +  LR +             +   A  +   F   + G      W  +        

		Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG------E 238

		

		Query: 258 SGFSETAMTFIMMLVGLGM---VLGNVLSGRISGRYSPLRIAAVTDFIIVLALLMLFFFG 314

		             F   A T  + L   G+   +   +++G ++ R    R   +         ++L F  

		Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298

		

		Query: 315 GMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAF--NLGSAVG 368

		                  I   +   G+      LQ +L +     E  G   G +A   +L S VG

		Sbjct: 299 RGWMAFPIMVLLASGGIG--MPALQAMLSRQV-DEERQGQLQGSLAALTSLTSIVG 351

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 40.4 bits (94), Expect = 4e-05

		 Identities = 40/264 (15%), Positives = 81/264 (30%), Gaps = 11/264 (4%)

		

		Query: 162  LNAKPKERAELLEELTGTEIYGKISAMVFEQHKSARTELEKLQAQASGVALLTPEQVQSL 221

		              A P E  E + E +  E     S  V +  + A     + +  A           Q+ 

		Sbjct: 1029 APATPSETTETVAENSKQE-----SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTN 1083

		

		Query: 222  TASLQVLTDEEKQLLTAQQQEQQSLNWLTRLD-ELQQEASRRQQALQQALAEEEKAQPQL 280

		              +      +E Q    ++          +++ E  QE  +    +     + E  QPQ 

		Sbjct: 1084 EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQA 1143

		

		Query: 281  AALSLAQPARNLRPHWE---RIAEHSAALAHTRQQIEEVNTRLQSTMALRASIRHHAAKQ 337

		                   P  N++         A+       T   +E+  T   +     + + +     

		Sbjct: 1144 EPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203

		

		Query: 338  SAELQQQQQSLNAWLQEHDRFRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLN 397

		             A  Q    S ++   ++   R   +         +  ++DR  +       T+    L+

		Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPA-TTSSNDRSTVALCDLTSTNTNAVLS 1262

		

		Query: 398  ALAAITLTLTADEVASALAQHAEQ 421

		               A    +  + V  A++QH  Q

		Sbjct: 1263 DARAKAQFVALN-VGKAVSQHISQ 1285

		

		

		

		 Score = 33.5 bits (76), Expect = 0.005

		 Identities = 27/139 (19%), Positives = 54/139 (38%), Gaps = 13/139 (9%)

		

		Query: 738  QQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQ 797

		            Q DV +  S  +  A+ D A              A   E T T  E  KQ  +   +  Q

		Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPP-------APATPSETTETVAENSKQESKTVEKNEQ 1056

		

		Query: 798  TLVTQTAETLTQHQQHRPGGLSLTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDAD 857

		                 TA+     ++ +       V       E+AQ+  + +E  T++ +    ++++  

		Sbjct: 1057 DATETTAQNREVAKEAKS-----NVKANTQTNEVAQSGSETKETQTTETKETATVEKEEK 1111

		

		Query: 858  NRQQQQTLMQQIAQMTQQV 876

		             + + +   Q++ ++T QV

		Sbjct: 1112 AKVETEK-TQEVPKVTSQV 1129

		

		

		>PF06291#Lambda prophage Bor protein

		          Length = 102

		

		 Score = 28.9 bits (64), Expect = 0.006

		 Identities = 12/37 (32%), Positives = 19/37 (51%)

		

		Query: 34 NMFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQ 70

		          N  KK+LF      ++ GCA+   T+   PT   P++

		Sbjct: 4  NKMKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKE 40

		

		

		>BCTERIALGSPF#Bacterial general secretion pathway protein F

		           signature.

		          Length = 408

		

		 Score = 29.4 bits (66), Expect = 0.034

		 Identities = 31/137 (22%), Positives = 54/137 (39%), Gaps = 24/137 (17%)

		

		Query: 247 IWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEA 306

		            W+ L L+ G +A   +LR          R+          + + P++    G+I     

		Sbjct: 228 PWMLLALLAGFMAFRVMLR------QEKRRVS-----FHRRLLHLPLI----GRIARGLN 272

		

		Query: 307 LARWPQTDGSWLSPDSFIPLAQQTGLS-EPLTLLIIRSVFEDMGDWLRQHPQQHISINLE 365

		            AR+ +T     +  S +PL Q   +S + ++    R       D +R+    H +  LE

		Sbjct: 273 TARYARTLSILNA--SAVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVSLHKA--LE 328

		

		Query: 366 STVLTSEKIPQLLREMI 382

		            T L     P ++R MI

		Sbjct: 329 QTAL----FPPMMRHMI 341

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 1368 bits (3543), Expect = 0.0

		 Identities = 802/1033 (77%), Positives = 916/1033 (88%), Gaps = 1/1033 (0%)

		

		Query: 1    MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60

		            M NFFI RPIFAWV+AII+M+AG LAIL+LPVAQYPTIAPPAV++SA+YPGADA+TVQDT

		Sbjct: 1    MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60

		

		Query: 61   VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120

		            VTQVIEQNMNGIDNLMYMSS SDS G+V ITLTF+SGTD DIAQVQVQNKLQLA PLLPQ

		Sbjct: 61   VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120

		

		Query: 121  EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180

		            EVQQQG+SVEKSSSS+LMV G ++ +   TQ+DISDYVA+N+KD +SR +GVGDVQLFG+

		Sbjct: 121  EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180

		

		Query: 181  QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240

		            QYAMRIW++ + LNK++LTPVDVI  +K QN Q+AAGQLGGTP + GQQLNASIIAQTR 

		Sbjct: 181  QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240

		

		Query: 241  TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300

		             + EEFGK+ L+VN DGS V L+DVA++ELGGENY++IA  NG+PA+GLGIKLATGANAL

		Sbjct: 241  KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300

		

		Query: 301  DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360

		            DTA AI+A+LA+++PFFP G+K++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ

		Sbjct: 301  DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360

		

		Query: 361  NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420

		            N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM

		Sbjct: 361  NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420

		

		Query: 421  AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480

		             E+ LPPKEAT KSM QIQGALVGIAMVLSAVF+PMAFFGGSTGAIYRQFSITIVSAMAL

		Sbjct: 421  MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480

		

		Query: 481  SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540

		            SVLVALILTPALCAT+LKP++   H E K GFFGWFN  F+ S +HYT+SVG IL STGR

		Sbjct: 481  SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539

		

		Query: 541  YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTNYYLT 600

		            YL++Y +IV GM  LF+RLPSSFLP+EDQGVF+TM+QLPAGATQERTQKVL++VT+YYL 

		Sbjct: 540  YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599

		

		Query: 601  KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660

		             EK NVESVF VNGF F+G+ QN G+AFVSLK W +R G+EN  EA+  RA     +I+D

		Sbjct: 600  NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659

		

		Query: 661  AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720

		              V  FN+PAIVELGTATGFDFELIDQAGLGH+ LTQARNQLL  AA+HP  L SVRPNG

		Sbjct: 660  GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719

		

		Query: 721  LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780

		            LEDT QFK+++DQEKAQALGVS++DIN T+  A GG+YVNDFIDRGRVKK+YV ++AK+R

		Sbjct: 720  LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779

		

		Query: 781  MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840

		            MLP+D+   YVR+A+G+MVPFSAF++S W YGSPRLERYNGLPSMEI G+AAPG S+G+A

		Sbjct: 780  MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839

		

		Query: 841  MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900

		            M LME LASKLP G+GYDWTGMSYQERLSGNQAP+L AIS +VVFLCLAALYESWSIP S

		Sbjct: 840  MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899

		

		Query: 901  VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960

		            VMLVVPLG++G LLAAT     NDVYF VGLLTTIGLSAKNAILIVEFAKDLM+KEGKG+

		Sbjct: 900  VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959

		

		Query: 961  IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF 1020

		            +EATL AVRMRLRPILMTSLAFILGV+PL IS GAGSGAQNAVG GVMGGMV+AT+LAIF

		Sbjct: 960  VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019

		

		Query: 1021 FVPVFFVVVRRRF 1033

		            FVPVFFVV+RR F

		Sbjct: 1020 FVPVFFVVIRRCF 1032

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 44.4 bits (105), Expect = 6e-07

		 Identities = 33/212 (15%), Positives = 71/212 (33%), Gaps = 23/212 (10%)

		

		Query: 112 TYQAAYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTA 171

		             +  Y  A  +L      + + Q+           Q +++   ++ L   +Q    +  

		Sbjct: 256 EQENKYVEAVNELR--VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313

		

		Query: 172 AKAAVETARINLAYTKVTSPISGRIGKSNV-TEGALVQNGQATALATVQQLDPIYVDVTQ 230

		               +         + + +P+S ++ +  V TEG +V   + T +  V + D + V    

		Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALV 372

		

		Query: 231 SSNDFLRLKQELA----------NGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVD 280

		            + D   +                          KV  I  D I+  + G +    ++++

		Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLV---GKVKNINLDAIEDQRLGLVFNVIISIE 429

		

		Query: 281 QTTGSITLRAIFPNPDHTLLPGMFVRARLEEG 312

		           +   S   + I       L  GM V A ++ G

		Sbjct: 430 ENCLSTGNKNIP------LSSGMAVTAEIKTG 455

		

		

		

		 Score = 34.4 bits (79), Expect = 7e-04

		 Identities = 24/125 (19%), Positives = 43/125 (34%), Gaps = 13/125 (10%)

		

		Query: 61  PLQITTELPGR-TSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQAAYDS 119

		            ++I     G+ T + R  E++P  + I+ +   KEG  +  G  L ++     +A    

		Sbjct: 79  QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA---- 134

		

		Query: 120 AKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETA 179

		              D  K Q++   A+L   RYQ L         E ++                      

		Sbjct: 135 ---DTLKTQSSLLQARLEQTRYQILS-----RSIELNKLPELKLPDEPYFQNVSEEEVLR 186

		

		Query: 180 RINLA 184

		             +L 

		Sbjct: 187 LTSLI 191

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score =  222 bits (567), Expect = 5e-76

		 Identities = 215/215 (100%), Positives = 215/215 (100%)

		

		Query: 1   MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60

		           MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS

		Sbjct: 1   MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60

		

		Query: 61  EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120

		           EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV

		Sbjct: 61  EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120

		

		Query: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180

		           GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF

		Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180

		

		Query: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215

		           APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE

		Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 31.7 bits (72), Expect = 0.017

		 Identities = 19/125 (15%), Positives = 40/125 (32%), Gaps = 6/125 (4%)

		

		Query: 28  QNTAFARASSNGDLPTKADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRVKEE 87

		            N    RA     L      +        +  L     L+ +      A L++ ++  E 

		Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSR--LDDFSSLLHKQAIAKHAVLEQENKYVEA 264

		

		Query: 88  TVQLRQKVAEAPEKMRQATAALTALSDVDND--EETRKIL--STLSLRQLETRVAQALDD 143

		             +LR   ++  +   +  +A      V      E    L  +T ++  L   +A+  + 

		Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEER 324

		

		Query: 144 LQNAQ 148

		            Q + 

		Sbjct: 325 QQASV 329

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 38.5 bits (89), Expect = 9e-05

		 Identities = 40/251 (15%), Positives = 78/251 (31%), Gaps = 31/251 (12%)

		

		Query: 404  PLPETTSQVLAARQQLQRVQGATKAKKSEPAA----ATRARPVNNAALERLASVTDRVQA 459

		            P  E  +Q +        +      +   P+        AR  + A +   A  T     

		Sbjct: 983  PEVEKRNQTVDTTN----ITTPNNIQADVPSVPSNNEEIARV-DEAPVPPPAPATPSETT 1037

		

		Query: 460  RPVPSALEKAPAKKEAYRWKATTPVMQQKE--------VVATPKALKKA---LEHEKTPE 508

		              V    ++     E     AT    Q +E        V A  +  + A    E ++T  

		Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097

		

		Query: 509  LAAKLAA---------EAIERDPWAAQVSQLSLPKLVEQVALNAWKE-ESDNAVCLHLRS 558

		               K  A            E+     +V+    PK  +   +    E   +N   ++++ 

		Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157

		

		Query: 559  SQRHLNNRGAQQKLAEALST-LKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARES 617

		             Q   N     ++ A+  S+ ++    E T V   N  V  P     A  +  +     +

		Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217

		

		Query: 618  IIADNNIQTLR 628

		               + + +++R

		Sbjct: 1218 KPKNRHRRSVR 1228

		

		

		>BLACTAMASEA#Beta-lactamase class A signature.

		          Length = 286

		

		 Score = 29.0 bits (65), Expect = 0.020

		 Identities = 11/43 (25%), Positives = 19/43 (44%)

		

		Query: 38 GQLAAVAIVTSDGNVYSAGDSDYRFALESISKVCTLALALEDV 80

		          G++  + +  + G   +A  +D RF + S  KV      L  V

		Sbjct: 38 GRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARV 80

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 77.8 bits (191), Expect = 5e-19

		 Identities = 49/212 (23%), Positives = 81/212 (38%), Gaps = 7/212 (3%)

		

		Query: 16  KSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNS----MGFT--GVLIDLDS 69

		           K   ITG + GIG   A  L  QG H+ A    P+ +E++ S              D+  

		Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68

		

		Query: 70  PESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRL 129

		             ++D     +       +  + N AG    G + ++S  + E  FS N  G    +  +

		Sbjct: 69  SAAIDEITARIEREMGP-IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127

		

		Query: 130 LPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEP 189

		              M+    G IV   S    +      AYA+SK A   ++  L +EL    I+ +++ P

		Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187

		

		Query: 190 GPIRTRFTDNVNQTQSDKPVENPGIAARFTLG 221

		           G   T    ++   ++       G    F  G

		Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTG 219

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 29.7 bits (66), Expect = 0.013

		 Identities = 12/20 (60%), Positives = 13/20 (65%)

		

		Query: 41  LVGESGSGKSTLLAILAGLD 60

		           L G  G GKSTL+  L GLD

		Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620

		

		

		>PF09025#YopR Core

		          Length = 143

		

		 Score = 28.1 bits (62), Expect = 0.020

		 Identities = 17/61 (27%), Positives = 25/61 (40%), Gaps = 8/61 (13%)

		

		Query: 126 EAVLIGQLECKSMVRMCAPLGSR--------LPLHASGAGKALLYPLAEEELMSIILQTG 177

		           + +   +LE K+M+R   PLG +        L       G   L  LA  EL  +I   G

		Sbjct: 68  QGLEADRLELKAMLRAELPLGRQQQTFLLQLLGAVEHAPGGEYLAQLARRELQVLIPLNG 127

		

		Query: 178 L 178

		           +

		Sbjct: 128 M 128

		

		

		>UREASE#Urea amidohydrolase (urease) protein signature.

		          Length = 570

		

		 Score = 56.3 bits (136), Expect = 1e-10

		 Identities = 39/163 (23%), Positives = 60/163 (36%), Gaps = 32/163 (19%)

		

		Query: 4   DLIIKNGTVILENEARVVDIAVKDGKIAAIG-------QD-----LGDAKDVMDASGLVV 51

		           D +I N  ++        DI +KDG+IAAIG       Q      +G   +V+   G +V

		Sbjct: 69  DTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIV 128

		

		Query: 52  SPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRAS------- 104

		           + G +D+H H   P +            A   G+T M+       PA    A+       

		Sbjct: 129 TAGGMDSHIHFICPQQIE---------EALMSGLTCMLGGGTG--PAHGTLATTCTPGPW 177

		

		Query: 105 -IELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFK 146

		            I    +AA     ++ A  G   +     L E+   G    K

		Sbjct: 178 HIARMIEAADA-FPMNLAFAGKGNASLPGALVEMVLGGATSLK 219

		

		

		>CARBMTKINASE#Bacterial carbamate kinase signature.

		          Length = 314

		

		 Score =  386 bits (994), Expect = e-138

		 Identities = 126/310 (40%), Positives = 176/310 (56%), Gaps = 16/310 (5%)

		

		Query: 2   KTLVVALGGNALLQRGEALTAENQYRNIASAVPALARL-ARSYRLAIVHGNGPQVGLLAL 60

		           K +V+ALGGNAL QRG+  + E    N+      +A + AR Y + I HGNGPQVG L L

		Sbjct: 3   KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62

		

		Query: 61  QNLAWKE---VEPYPLDVLVAESQGMIGYMLAQSLSAQPQM----PHVTTVLTRIEVSPD 113

		              A +    +   P+DV  A SQG IGYM+ Q+L  + +       V T++T+  V  +

		Sbjct: 63  HMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKN 122

		

		Query: 114 DPAFLQPEKFIGPVYQPEEQEALEATYGWQMKRD-GKYLRRVVASPQPRKILDSEAIELL 172

		           DPAF  P K +GP Y  E  + L    GW +K D G+  RRVV SP P+  +++E I+ L

		Sbjct: 123 DPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKL 182

		

		Query: 173 LKEGHVVICSGGGGVPVTEDG---AGSEAVIDKDLAAALLAEQINADGLVILTDADAVYE 229

		           ++ G +VI SGGGGVPV  +     G EAVIDKDLA   LAE++NAD  +ILTD +    

		Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242

		

		Query: 230 NWGTPQQRAIRHATPDELAPFAKAD----GSMGPKVTAVSGYVRSRGKPAWIGALSRIEE 285

		            +GT +++ +R    +EL  + +      GSMGPKV A   ++   G+ A I  L +  E

		Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVE 302

		

		Query: 286 TLAGEAGTCI 295

		            L G+ GT +

		Sbjct: 303 ALEGKTGTQV 312

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 29.4 bits (66), Expect = 0.030

		 Identities = 16/150 (10%), Positives = 44/150 (29%), Gaps = 8/150 (5%)

		

		Query: 299 RSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTP----- 353

		            +    ++ +L QAR    R     R  +    P      E  F    +++         

		Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192

		

		Query: 354 EAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEV 413

		           E +S   +   +      +  A    + + + +   +  + +   + F           +

		Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS---LLHKQAI 249

		

		Query: 414 AEIEALIQQRLDARKAKDWAAADAARDRLN 443

		           A+   L Q+        +     +  +++ 

		Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIE 279

		

		

		>ENTSNTHTASED#Enterobactin synthetase component D signature.

		          Length = 234

		

		 Score =  267 bits (684), Expect = 7e-93

		 Identities = 108/183 (59%), Positives = 132/183 (72%), Gaps = 1/183 (0%)

		

		Query: 51  MKTTHTSLPFAGHTLHFVEFDPASFREQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAIYA 110

		           M T+H  LPFAGH LH V+FD +SFRE DLLWLPH+ +L+ AGRKRK EHLAGRIAA++A

		Sbjct: 1   MLTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA 60

		

		Query: 111 LREYGYKCVPAIGELRQPVWPAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSAQTAREL 170

		           LRE G + VP +G+ RQP+WP G++GSISHC TTALAV+SRQ IGIDIE+I S  TA EL

		Sbjct: 61  LREVGVRTVPGMGDKRQPLWPDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATEL 120

		

		Query: 171 TDNIITPAEHKRLADCGLAFPLALTLAFSAKESAFKA-SEIQTDADFLDYQIISRNKQQV 229

		             +II   E + L    L FPLALTLAFSAKES +KA S+  T   F   ++ S     +

		Sbjct: 121 APSIIDSDERQILQASLLPFPLALTLAFSAKESVYKAFSDRVTLPGFNSAKVTSLTATHI 180

		

		Query: 230 IIH 232

		            +H

		Sbjct: 181 SLH 183

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 36.3 bits (84), Expect = 2e-04

		 Identities = 82/394 (20%), Positives = 146/394 (37%), Gaps = 38/394 (9%)

		

		Query: 27  FISIVSLGLLGVAVPVQIQMMTHSTWQV---GLSVTLTGGAMFVGLMVGGVLADRYERKK 83

		            +  V +GL+   +P  ++ + HS       G+ + L     F    V G L+DR+ R+ 

		Sbjct: 15  ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74

		

		Query: 84  VILLARGTCGIGFIGLCLNALL--PEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGR 141

		           V+L       +   G  ++  +    P L  +Y+  +  G   + G  A  A    +   

		Sbjct: 75  VLL-------VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA-GAYIADITDG 126

		

		Query: 142 ENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPP 201

		           +   +           G V  P++GGL+   GG + +    AA     L  L     LP 

		Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLM---GGFSPHAPFFAAAALNGLNFLTGCFLLPE 183

		

		Query: 202 PPQPREHPLK----SLLAGFRFLLASPLVGGIALLGGLLTMAS----AVRVLYPALADNW 253

		             +    PL+    + LA FR+     +V  +  +  ++ +      A+ V++    D +

		Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG--EDRF 241

		

		Query: 254 QMSAAQIGFLYAAIP-LGAAIGALTSGKLAHSVRPGLLMLLSTLG---AFLAIGLFGLMP 309

		              A  IG   AA   L +   A+ +G +A  +     ++L  +     ++ +       

		Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301

		

		Query: 310 MWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGG 369

		           M    +V LA  G            ML  Q  E   G++ G   A       +G  L   

		Sbjct: 302 MAFPIMVLLASGGIGMPALQ----AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357

		

		Query: 370 LGAMMTPVASASASGFGLLIIGVLLLLVLVELRR 403

		           + A     +  + +G+  +    L LL L  LRR

		Sbjct: 358 IYA----ASITTWNGWAWIAGAALYLLCLPALRR 387

		

		

		>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature.

		          Length = 296

		

		 Score = 62.7 bits (152), Expect = 2e-13

		 Identities = 60/280 (21%), Positives = 100/280 (35%), Gaps = 35/280 (12%)

		

		Query: 40  HTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQ 99

		           H     P RIV+        LLA+               VAD   + R W     E  L 

		Sbjct: 29  HAAAIDPNRIVALEWLPVELLLALGIVPYG---------VADTINY-RLW---VSEPPLP 75

		

		Query: 100 RLYIG-----EPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKS--- 151

		              I      EP+ E +    P  ++ SA  G S     + L+ IAP    N+ D     

		Sbjct: 76  DSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPS----PEMLARIAPGRGFNFSDGKQPL 131

		

		Query: 152 --WQSLLTQLGEITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLW 209

		              +  LT++ ++   +  A   +AQ++  + + K +          +          ++

		Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVF 191

		

		Query: 210 TPESAQGQMLEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQ 269

		            P S   ++L++ G          NA Q +        +  + LAA  + + L     + 

		Sbjct: 192 GPNSLFQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNS 243

		

		Query: 270 KDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQ 309

		           KD DA+ A PL   +P V+  +   +    F     SAM 

		Sbjct: 244 KDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMH 283

		

		

		>ISCHRISMTASE#Isochorismatase signature.

		          Length = 312

		

		 Score =  443 bits (1141), Expect = e-161

		 Identities = 146/299 (48%), Positives = 195/299 (65%), Gaps = 18/299 (6%)

		

		Query: 1   MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANI 60

		           MAIP +Q Y +P + D+PQNKV W  +P RA LLIHDMQ+YFV  +      + ++ ANI

		Sbjct: 1   MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60

		

		Query: 61  AALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTV 120

		             L++ C Q  IPV YTAQP  Q+ +DRALL D WGPGL   P ++K++  L P+ DD V

		Sbjct: 61  RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120

		

		Query: 121 LVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 180

		           L KWRYSAF R+ L +M+++ GR+QLIITG+YAHIGC+ TA +AFM DIK F V DA+AD

		Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180

		

		Query: 181 FSRDEHLMSLKYVAGRSGRVVMTEELL------PAPIPASKAE-----------LREVIL 223

		           FS ++H M+L+Y AGR    VMT+ LL      PA +  + A            +R+ I 

		Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240

		

		Query: 224 PLLDESDEPFDDD-NLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLS 281

		            LL E+ E   D  +L+D GLDSVR+M L  +WR+   ++ FV LA+ PTI+ W KLL+

		Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  362 bits (930), Expect = e-130

		 Identities = 110/258 (42%), Positives = 150/258 (58%), Gaps = 20/258 (7%)

		

		Query: 5   GKNVWVTGAGKGIGYATAMAFVEAGAKVTGFD---------------QAFTQEQYPFATE 49

		           GK  ++TGA +GIG A A      GA +   D               +A   E +P    

		Sbjct: 8   GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP---- 63

		

		Query: 50  VMDVADAAQVAQVCQRLLAETERLDVLVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109

		             DV D+A + ++  R+  E   +D+LVN AG+LR G    LS E+W+ TF+VN  G FN

		Sbjct: 64  -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122

		

		Query: 110 LFQQTMNQFRHQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169

		             +        +R G+IVTV S+ A  PR  M+AY +SKAA       +GLELA   +RC

		Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182

		

		Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229

		           N+VSPGST+TDMQ +LW  ++  EQ I+G  E FK GIPL K+A+P +IA+ +LFL S  

		Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242

		

		Query: 230 ASHITLQDIVVDGGSTLG 247

		           A HIT+ ++ VDGG+TLG

		Sbjct: 243 AGHITMHNLCVDGGATLG 260

		

		

		>BCTLIPOCALIN#Bacterial lipocalin signature.

		          Length = 171

		

		 Score = 28.8 bits (64), Expect = 0.017

		 Identities = 18/98 (18%), Positives = 39/98 (39%), Gaps = 13/98 (13%)

		

		Query: 50  QGITIIKTFDAPGGMKGYLGKYQDMGVTIYLTPDGKHAISG--YMYNEKGENLSNTLIEK 107

		           + +  +  F+       YLGK+ ++    +    G   ++    + N+ G ++ N     

		Sbjct: 21  ESVKPVSDFEL----NNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLN----- 71

		

		Query: 108 EIYAPAGREMWQRMEQSHWLLDGKKDAPVIVYVFADPF 145

		             Y+   +  W+  E   + ++G  D  + V  F  PF

		Sbjct: 72  RGYSEE-KGEWKEAEGKAYFVNGSTDGYLKVSFFG-PF 107

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 92.2 bits (229), Expect = 8e-24

		 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 1/125 (0%)

		

		Query: 2   TNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGI 61

		             +L+ +D+ AIR  L  AL   G  V             A    DL++ D+ +PD +  

		Sbjct: 4   ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63

		

		Query: 62  EFIRDLRQWSA-VPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS 120

		           + +  +++    +PV+V+SA++     I A + GA DYL KPF + EL   +  AL    

		Sbjct: 64  DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123

		

		Query: 121 ATTTP 125

		              + 

		Sbjct: 124 RRPSK 128

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 32.5 bits (74), Expect = 0.007

		 Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 4/48 (8%)

		

		Query: 786 LLENAVKYAGAQAE----IGINAHVEGENLQLDVWDNGPGLPPGQEQT 829

		           L+EN +K+  AQ      I +    +   + L+V + G       +++

		Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES 310

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score = 31.4 bits (71), Expect = 0.003

		 Identities = 11/41 (26%), Positives = 23/41 (56%), Gaps = 1/41 (2%)

		

		Query: 14  VDDAPRMQDYTLEAEEGRDM-MLLDALIQLKEKDPSLSFRR 53

		           +++   +   T+E  + +   MLLDAL+++ + DP L +  

		Sbjct: 339 IENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 30.2 bits (68), Expect = 0.017

		 Identities = 27/196 (13%), Positives = 56/196 (28%), Gaps = 12/196 (6%)

		

		Query: 48  EVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSE-EKASTPAQRQQASL 106

		           E+    + I+  ++  EG +V    +L +L    +       +S   +A     R Q   

		Sbjct: 98  EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157

		

		Query: 107 EEQNNDAL----SPAIRRLLAEHNLDASAIKGTGVGGRLTRED----VEKHLAKAPAKES 158

		                + L     P           +   +         T ++     E +L K  A+  

		Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217

		

		Query: 159 APAAAAPAAQPTLAARSEKRVPMTRLRKRVA---ERLLEAKNSTAMLTTFNEVNMKPIMD 215

		              A     +        +    + L  + A     +LE +N          V    +  

		Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277

		

		Query: 216 LRKQYGEAFEKRHGIR 231

		           +  +   A E+   + 

		Sbjct: 278 IESEILSAKEEYQLVT 293

		

		

		>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD

		           chaperone signature.

		          Length = 168

		

		 Score = 28.4 bits (63), Expect = 0.025

		 Identities = 18/65 (27%), Positives = 26/65 (40%)

		

		Query: 255 AMQNSGDTQLARKYNREGEAVYKTGQLEQAIQLFQQATELDGNYGQAFSNLGLAYQKNGN 314

		           AM N   +    +        Y++G+ E A ++FQ    LD    + F  LG   Q  G 

		Sbjct: 26  AMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQ 85

		

		Query: 315 IAEAI 319

		              AI

		Sbjct: 86  YDLAI 90

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 58.9 bits (142), Expect = 2e-11

		 Identities = 33/199 (16%), Positives = 68/199 (34%), Gaps = 8/199 (4%)

		

		Query: 99   EQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEE 158

		            E E+  Q             QA+  +          E A    A          ++  E 

		Sbjct: 984  EVEKRNQTVDTTNITTPNNIQADVPSVP----SNNEEIARVDEAPVPPPAPATPSETTET 1039

		

		Query: 159  AAK--KAAADAKKKAEAEAAKAAVEAQKKAEAAAAALKKKAEAAEAA--AAEARKKAATE 214

		             A+  K  +   +K E +A +   + ++ A+ A + +K   +  E A   +E ++   TE

		Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099

		

		Query: 215  AAEKAKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKK 274

		              E A  E E+KA  E     +        + K+   +    +A   ++        + +

		Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159

		

		Query: 275  AAAAKAAAEKAAAAKAAAE 293

		            +     A  +  A + ++ 

		Sbjct: 1160 SQTNTTADTEQPAKETSSN 1178

		

		

		

		 Score = 56.6 bits (136), Expect = 1e-10

		 Identities = 30/236 (12%), Positives = 85/236 (36%), Gaps = 11/236 (4%)

		

		Query: 68   QSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQA 127

		            Q+   S   ++E+    ++           +E         ++ +   +K   E+ A + 

		Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN--EQDATET 1061

		

		Query: 128  ELKQKQ-AEEAAAKAAAD------AKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAV 180

		              + ++ A+EA +   A+      A++ +E       E  + A  + ++KA+ E  K   

		Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQE 1121

		

		Query: 181  EAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAA 240

		              +  ++ +    ++++E  +  A  AR+   T   ++ +++    A  E+ A +  +  

		Sbjct: 1122 VPKVTSQVSPK--QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV 1179

		

		Query: 241  EKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEADD 296

		            E+   +        +     +    A         ++ K       + ++     +

		Sbjct: 1180 EQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE 1235

		

		

		

		 Score = 56.2 bits (135), Expect = 2e-10

		 Identities = 30/229 (13%), Positives = 72/229 (31%), Gaps = 4/229 (1%)

		

		Query: 66   RMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAK 125

		            R  ++E+ +      +  +  Q+  E +E Q  E +    +EKE  A  E +K  E    

		Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125

		

		Query: 126  QAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAVEAQKK 185

		             +++  KQ +    +  A+   + +      +E   +    A  +  A+   + VE    

		Sbjct: 1126 TSQVSPKQEQSETVQPQAEPARENDP-TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVT 1184

		

		Query: 186  AEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAA---EK 242

		                        E  E       +      +        +++        + A     ++

		Sbjct: 1185 ESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDR 1244

		

		Query: 243  AAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAA 291

		            +                +D +A A+  A +   A ++  ++     +  

		Sbjct: 1245 STVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293

		

		

		

		 Score = 55.8 bits (134), Expect = 2e-10

		 Identities = 32/265 (12%), Positives = 86/265 (32%), Gaps = 14/265 (5%)

		

		Query: 51   DAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAE-ELREKQAAEQER------L 103

		            D   V   A     +  ++   ++K+  +  +  EQ A E   + ++ A++ +       

		Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080

		

		Query: 104  KQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKA 163

		            +  E  +  ++ ++ Q     K+    +K+      KA  + +   E     ++ + K+ 

		Sbjct: 1081 QTNEVAQSGSETKETQ-TTETKETATVEKE-----EKAKVETEKTQEVPKVTSQVSPKQE 1134

		

		Query: 164  AADA-KKKAEAEAAKAAVEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAE 222

		             ++  + +AE           K+ ++         + A+  ++   +             

		Sbjct: 1135 QSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194

		

		Query: 223  AEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAA 282

		              +       A  +     +++   K   + +      + + A   +      A     +

		Sbjct: 1195 VVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTS 1254

		

		Query: 283  EKAAAAKAAAEADDIFGELSSGKNA 307

		                A  + A A   F  L+ GK  

		Sbjct: 1255 TNTNAVLSDARAKAQFVALNVGKAV 1279

		

		

		>ABC2TRNSPORT#ABC-2 type transport system membrane protein

		           signature.

		          Length = 262

		

		 Score = 46.1 bits (109), Expect = 9e-08

		 Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 5/146 (3%)

		

		Query: 197 AREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALF 256

		            R   Q T + +L + L    I +G+   A   A         IG+ A  + +   L+L 

		Sbjct: 92  GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGA---GIGVVAAALGYTQWLSLL 148

		

		Query: 257 YFTMVV--YGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPMWLQN 314

		           Y   V+   GL+    G+++++L  +         + + P + LSG V PV+ +P+  Q 

		Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208

		

		Query: 315 LTWINPIRHFTDITKQIYLKDASLDI 340

		                P+ H  D+ + I L    +D+

		Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDV 234

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 31.2 bits (70), Expect = 0.012

		 Identities = 20/90 (22%), Positives = 28/90 (31%), Gaps = 21/90 (23%)

		

		Query: 298 TPRFEDAFIDLLGGAGTSESPLGAILHTVGGTPGETVIEAKELTKKFGDFAATDHVNFAV 357

		            PR E   + +LG       P               +   + + K         HV   +

		Sbjct: 547 VPRLEKWLVHVLGKTPDDYKP-------------RRLRYLQLVGKYI----LMGHVARVM 589

		

		Query: 358 KRGEIFG----LLGPNGAGKSTTFKMMCGL 383

		           + G  F     L G  G GKST    + GL

		Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619

		

		

		

		 Score = 29.3 bits (65), Expect = 0.047

		 Identities = 11/23 (47%), Positives = 13/23 (56%)

		

		Query: 39  YVTGLVGPDGAGKTTLMRMLAGL 61

		           Y   L G  G GK+TL+  L GL

		Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 62.2 bits (151), Expect = 6e-13

		 Identities = 42/259 (16%), Positives = 92/259 (35%), Gaps = 25/259 (9%)

		

		Query: 83  ALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRT 142

		              Q +  +   +A+   +LA     E        +    +    +    +   L +   

		Sbjct: 201 QKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENK 260

		

		Query: 143 ISA--NDLENARSSRDQAQATLKSAQDKLRQYRSGNREQ---DIAQAKASLEQAQAQLAQ 197

		                N+L   +S  +Q ++ + SA+++ +      + +    + Q   ++     +LA+

		Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAK 320

		

		Query: 198 AELNLQDSTLVAPSDGTLLTRAV-EPGTVLNEGGTVFTVSLT-RPVWVRAYVDERNLDQA 255

		            E   Q S + AP    +    V   G V+    T+  +      + V A V  +++   

		Sbjct: 321 NEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFI 380

		

		Query: 256 QPGRKVLLYTDGRPNKPYH---GQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVT--- 309

		             G+  ++  +  P   Y    G++  ++  A          D R  LV+ + I +    

		Sbjct: 381 NVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA--------IEDQRLGLVFNVIISIEENC 432

		

		Query: 310 ----DADDALRQGMPVTVQ 324

		               + +  L  GM VT +

		Sbjct: 433 LSTGNKNIPLSSGMAVTAE 451

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 72.7 bits (178), Expect = 7e-18

		 Identities = 33/214 (15%), Positives = 78/214 (36%), Gaps = 17/214 (7%)

		

		Query: 13  KGEQAKKQLIAAALAQFGEYGMNATT-REIAAQAGQNIAAITYYFGSKEDLYLACAQWIA 71

		           + ++ ++ ++  AL  F + G+++T+  EIA  AG    AI ++F  K DL+    +   

		Sbjct: 8   EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67

		

		Query: 72  DFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRACKNMIKLLTQDDTVNLSKFISREQL 131

		             IGE      E   +    P    + +RE+++   ++ +    +   + +  F   E +

		Sbjct: 68  SNIGELEL---EYQAKFPGDP---LSVLREILIHVLESTVTEERRRLLMEII-FHKCEFV 120

		

		Query: 132 SPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDANDTRMILHTHALIGEILAFRLGKETIL 191

		              A        +    +  + + +      +A      L T      +  +  G     

		Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKH--CIEAKMLPADLMTRRAAIIMRGYISG----- 173

		

		Query: 192 LRTGWTAFDEEKTELINQTVTCHIDLILQGLSQR 225

		           L   W    +     + +    ++ ++L+     

		Sbjct: 174 LMENWLFAPQSFD--LKKEARDYVAILLEMYLLC 205

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 29.8 bits (67), Expect = 0.026

		 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%)

		

		Query: 246 QQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG-NKSQGARTRALADFKSGDIRVLVATDI 304

		           Q VLV T +   +  ++ +L K GI+   ++    +  A   A A + +    V +AT++

		Sbjct: 450 QPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNM 506

		

		Query: 305 AARGLDI 311

		           A RG DI

		Sbjct: 507 AGRGTDI 513

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 33.7 bits (77), Expect = 0.001

		 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 6/150 (4%)

		

		Query: 239 LLIGVVVLAMAFAEGSANDWL-PLLMVDGHGFSP-TSGSLIYAGFTLGMTVGRFIGGWFI 296

		            +IGV+   + F   +    + P +M D H  S    GS+I    T+ + +  +IGG  +

		Sbjct: 258 FMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILV 317

		

		Query: 297 DHYSRVAVVR-ASALM--GALGIGLIIFVDSAWVA-GVSVVLWGLGASLGFPLTISAASD 352

		           D    + V+      +    L    ++   S ++   +  VL GL  +     TI ++S 

		Sbjct: 318 DRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSL 377

		

		Query: 353 TGPDAPTRVSVVATTGYLAFLVGPPLLGYL 382

		              +A   +S++  T +L+   G  ++G L

		Sbjct: 378 KQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 52.3 bits (125), Expect = 1e-10

		 Identities = 14/81 (17%), Positives = 31/81 (38%)

		

		Query: 12 RRANDPQRREKIIQATLEAVKLYGIHAVTHRKIAALAGVPLGSMTYYFSGIDELLLEAFS 71

		           +    + R+ I+   L      G+ + +  +IA  AGV  G++ ++F    +L  E + 

		Sbjct: 5  TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64

		

		Query: 72 RFTEIMSRQYQAFFSDVSDAP 92

		               +      + +     P

		Sbjct: 65 LSESNIGELELEYQAKFPGDP 85

		

		

		>DNABINDNGFIS#DNA-binding protein FIS signature.

		          Length = 98

		

		 Score = 29.6 bits (66), Expect = 0.012

		 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 9/72 (12%)

		

		Query: 100 QQRFNPDMVILADVNAQPSHISKPLMQRIE-----YFSSL-GRP--KAYSRYLRETIKPC 151

		           +QR N D++ ++ VN+Q     KPL   ++     YF+ L G+     Y   L E  +P 

		Sbjct: 3   EQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPL 62

		

		Query: 152 LER-LEHIRDSQ 162

		           L+  +++ R +Q

		Sbjct: 63  LDMVMQYTRGNQ 74

		

		

		>60KDINNERMP#60kDa inner membrane protein signature.

		          Length = 548

		

		 Score = 26.8 bits (59), Expect = 0.033

		 Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 14/80 (17%)

		

		Query: 3  RLLLVVLALLLAALGWQTWR-------LADASQTISTQSDELQSKSQALAKSNSQLIS-- 53

		          R LLV+  L ++ + WQ W         A  +   +T +    +     A    +LIS  

		Sbjct: 5  RNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVK 64

		

		Query: 54 -----LSILTETNNREQARL 68

		               L+I T   + EQA L

		Sbjct: 65 TDVLDLTINTRGGDVEQALL 84

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 28.7 bits (64), Expect = 0.049

		 Identities = 20/114 (17%), Positives = 34/114 (29%), Gaps = 11/114 (9%)

		

		Query: 50  PFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSIFMSGIGTLL--------FFFITGGR 101

		           PF    + G      + G   ++P +M     LS    G   +         F +I G  

		Sbjct: 257 PFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGIL 316

		

		Query: 102 VPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKI 155

		           V          +GV   +  F         +      +   +V+ + GL   K 

		Sbjct: 317 VDRRGPLYVLNIGVTFLSVSFLTASFLLETTSW---FMTIIIVFVLGGLSFTKT 367