>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 40.2 bits (94), Expect = 6e-06 Identities = 40/194 (20%), Positives = 74/194 (38%), Gaps = 26/194 (13%) Query: 5 RTLASLFVVCLASLPVLHAQAAKPAVQELASGSAL-------LVDLNTNEVLYSSNPDMV 57 R + + LA+LP+ + +P Q S S L +DL + L + D Sbjct: 2 RYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADER 61 Query: 58 VPIASVTKLMTAIVALD----AKLPLDQVLPVTIRDAKEMQGVFSRVRIGSEISRRELLL 113 P+ S K++ L L++ + +D + V S + ++ EL Sbjct: 62 FPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPV-SEKHLADGMTVGELCA 120 Query: 114 LTLMSSENRAAASLAHHYPGGYSAFIQAMNAKARALG--MSRTYYVEPTGLSE------R 165 + S+N +AA+L GG + A R +G ++R E L+E R Sbjct: 121 AAITMSDN-SAANLLLATVGG----PAGLTAFLRQIGDNVTRLDRWETE-LNEALPGDAR 174 Query: 166 NVSSANDLVKLIRA 179 + ++ + +R Sbjct: 175 DTTTPASMAATLRK 188
>BACSURFANTGN#Yersinia/Haemophilus virulence surface antigen signature. Length = 322 Score = 30.5 bits (68), Expect = 0.019 Identities = 26/120 (21%), Positives = 42/120 (35%), Gaps = 17/120 (14%) Query: 7 HLSRRSALPRLVIAALAAAYLPASLADTAASALSLG------SSTVTASQSGGGLPTSSV 60 LS SA L A L + A ALS S+T+ +QSG + + Sbjct: 11 QLSNYSAGENLQSATLTEGVIGAHRVKVET-ALSHSNLQKKLSATIKHNQSGRSMLDRKL 69 Query: 61 ISSVDLLGGDILEQQPVLYSWELFRRAPGVMLTEFGQGTSS-----GKLSFRGFNGEGEV 115 S G ++ +S ++R V+ T S G ++F+ +G Sbjct: 70 TSD-----GKANQRSSFTFSMIMYRMIHFVLSTRVPAVRESVANYGGNINFKFAQTKGAF 124
>PF06580#Sensor histidine kinase Length = 349 Score = 27.9 bits (62), Expect = 0.026 Identities = 20/92 (21%), Positives = 34/92 (36%), Gaps = 11/92 (11%) Query: 116 ALNAGNTLLRNPDVNAVTLIDVI--VFRH--ASDAQDNVALWAHELKHVEQYLDWGVAEF 171 ALN L+ A ++ + + R+ V+L A EL V+ YL +F Sbjct: 178 ALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSL-ADELTVVDSYLQLASIQF 236 Query: 172 ARRYTLDY------RAVEQPAYALELEVEKAL 197 R + V+ P ++ VE + Sbjct: 237 EDRLQFENQINPAIMDVQVPPMLVQTLVENGI 268
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 173 bits (441), Expect = 2e-52 Identities = 95/298 (31%), Positives = 130/298 (43%), Gaps = 47/298 (15%) Query: 147 APYGSGAL---AAWNAGAACSSQIHVGIIDEGVMTTHGDLRANIWINPGEGSRADRKDND 203 P G + A WN + V ++D G H DL+A I Sbjct: 22 IPRGVEMIQAPAVWNQTRG--RGVKVAVLDTGCDADHPDLKARI---------------- 63 Query: 204 RNGFIDDIHGWDFSANDASVYDGPADD--HGSHVAGTVAAVANNGAGVFGVCPSARLITA 261 I G +F+ +D + D HG+HVAGT+AA N GV GV P A L+ Sbjct: 64 -------IGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAAT-ENENGVVGVAPEADLLII 115 Query: 262 KFLGANG-GTTAGAVKAVNYLTQLKLAKKINLVATNNSWGGGGYSQALYDAIRAAGNANI 320 K L G G ++ + Y + +K++++ + S GG L++A++ A + I Sbjct: 116 KVLNKQGSGQYDWIIQGIYYAIE----QKVDII--SMSLGGPEDVPELHEAVKKAVASQI 169 Query: 321 LFVAAAGNSGLDID--ATPSYPASYQLPNVIAVAAIGQNGQRAGFSNYGAKSVHIAAPGV 378 L + AAGN G D YP Y VI+V AI + + FSN V + APG Sbjct: 170 LVMCAAGNEGDGDDRTDELGYPGCY--NEVISVGAINFDRHASEFSNSNN-EVDLVAPGE 226 Query: 379 DIVSTVPTAKGAAGYAYMSGTSMAAPHVTGAAALYASLNPCATAAQTREALLRLAVQD 436 DI+STVP K YA SGTSMA PHV GA AL L + E L + Sbjct: 227 DILSTVPGGK----YATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIK 280
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 179 bits (457), Expect = 5e-56 Identities = 85/349 (24%), Positives = 148/349 (42%), Gaps = 47/349 (13%) Query: 2 ILVTGGAGYIGSHAVLELLQAGHEVLVLDNLCNSSQLAL--DRVEQLAGRPLHFVKGDVR 59 LVTG AG+IG H LL+AGH+V+ +DNL + ++L R+E LA F K D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62 Query: 60 NRALLKALFAAYPVTAVMHFAGLKAVGESVREPLRYYETNVGGSIALCQAMAEAGVFKLV 119 +R + LFA+ V AV S+ P Y ++N+ G + + + + L+ Sbjct: 63 DREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHLL 122 Query: 120 FSSSATVYGESPVMPITEDRPTGVPTNPYGQSKLMAE------NVLKGLADSDPRWSIGL 173 ++SS++VYG + MP + D P + Y +K E + L GL + G Sbjct: 123 YASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLP------ATG- 175 Query: 174 LRYFNPIGAHESGLIGEDPNGVPNNLLPYMLQVAVGRRKQLNVYGNDYPTLDGTGVRDYI 233 LR+F G P G P ++ + A+ K ++VY G RD+ Sbjct: 176 LRFFTVYG----------PWGRP-DMALFKFTKAMLEGKSIDVYN------YGKMKRDFT 218 Query: 234 HVVDLAKGHLKALERLQLIHGVST---------------WNLGTGKGHSVREMITAFEEV 278 ++ D+A+ ++ + + T +N+G + + I A E+ Sbjct: 219 YIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDA 278 Query: 279 TGRSLPHVIKPRRSGDIAQCWSDPSKAERELGWRAEKDLTSMLADAWRW 327 G + P + GD+ + +D +G+ E + + + W Sbjct: 279 LGIEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNW 327
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 35.1 bits (81), Expect = 4e-04 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 20/92 (21%) Query: 288 IAAAD-LAQRGVLDILSSD--------------YYPASLLQAALGLAEQDNGYD----LP 328 IAA D L G I+SSD + A ++ G +++ G + + Sbjct: 344 IAAEDILHDIGAFSIISSDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVK 403 Query: 329 RAIATISLAPARAAGLDDR-GEIAVGLRADLV 359 R IA ++ PA A GL G + VG RADLV Sbjct: 404 RYIAKYTINPAIAHGLSHEIGSLEVGKRADLV 435
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.0 bits (72), Expect = 0.002 Identities = 12/24 (50%), Positives = 14/24 (58%) Query: 39 CLVLHGQSGAGKSTLLRTLYGNYL 62 +VL G G GKSTL+ TL G Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDF 621
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 100 bits (251), Expect = 9e-28 Identities = 70/247 (28%), Positives = 107/247 (43%), Gaps = 14/247 (5%) Query: 4 KIVFITGATSGFGRATARRFAEAGWALVLTGRRSERLEELQSELSAKVPVHIA-TLDVRH 62 KI FITGA G G A AR A G + E+LE++ S L A+ A DVR Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 63 AGAVKEVVEQLPAEFSQIDCLVNNAGLALAPQPAQQVDLTDWHTMIDTNITGLVNVTHAL 122 + A+ E+ ++ E ID LVN AG+ L P + +W N TG+ N + ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 123 LPTLIATGKGASIVNIGSVAGHWPYPGGHVYGATKAFVEQFGYNLRCDLLGTGVRVTDIA 182 ++ + SIV +GS P Y ++KA F L +L +R ++ Sbjct: 128 SKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PGMAETEFTLVRTKGDQAASDKL------YRGTTPLTA----EDIAEQI-FYVATLPDHI 231 PG ET+ + A + ++ PL DIA+ + F V+ HI Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 232 NINRLEV 238 ++ L V Sbjct: 247 TMHNLCV 253
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.029 Identities = 26/118 (22%), Positives = 45/118 (38%), Gaps = 14/118 (11%) Query: 129 LGLSLTTVEGLLTEAAEPAYLANINAD------------NQLVIAGSDAAMAAVAARAKA 176 +G L TV G+L+ + L+N +AD +++ + A+ A Sbjct: 238 IGAGLDTVSGILSAISASFILSNADADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAA 297 Query: 177 LGASCARRLAMSVPSHCALLEQPARELAEAFADVSLRAPQVRYLSSSSARPIFDTERL 234 G S + A + S L P L + AD RA ++ S + +D + L Sbjct: 298 QGLSTSAAAAGLIASAVTLAISPLSFL--SIADKFKRANKIEEYSQRFKKLGYDGDSL 353
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.2 bits (203), Expect = 2e-20 Identities = 35/127 (27%), Positives = 61/127 (48%) Query: 2 RILLVEDHPQLAESVAQALRAAGWTVDLLQDGIAADLALASEDYALAILDVGLPRLDGFQ 61 IL+ +D + + QAL AG+ V + + +A+ D L + DV +P + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLARLRERGKTLPVLMLTARGEVSDRVHGLNLGADDYLAKPFELSELEARVKALLRRSVG 121 +L R+++ LPVL+++A+ + GA DYL KPF+L+EL + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 GGERQQR 128 + + Sbjct: 125 RPSKLED 131
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.0 bits (65), Expect = 0.039 Identities = 17/80 (21%), Positives = 30/80 (37%), Gaps = 9/80 (11%) Query: 225 ALGALPALLGFSVPDV--------EQIRASGALGGDLEGARQHWAGWLVGVLLIYGLLPR 276 A+ + LL VP V + + S + + A + + W++ LL + R Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 277 LLLAGFSLWRWRRGRAALKL 296 ++L R R L L Sbjct: 243 VMLRQ-EKRRVSFHRRLLHL 261
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 29.3 bits (65), Expect = 0.008 Identities = 18/46 (39%), Positives = 23/46 (50%) Query: 58 RPLPGRLNLVVSRQADLQLDGAETFTDLDAALVRAEQWAREQGVDE 103 R L L +S A QLD +DLD LV ++ RE GVD+ Sbjct: 446 RELSDLLRTHLSSAATKQLDMGGVLSDLDTMLVALDKAEREGGVDK 491
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 135 bits (340), Expect = 1e-40 Identities = 75/254 (29%), Positives = 119/254 (46%), Gaps = 12/254 (4%) Query: 3 LQNQVALVTGSTQGIGRGIALRLAEEGADIVINGRQDDEQARESLEQ-VHARGRRVCFIA 61 ++ ++A +TG+ QGIG +A LA +GA I + + E + + A R Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIA--AVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 62 ADVGDVEQCQRLVREGIEQMGRLDILVNNAGVQRHAAFLDAQADDYDQVLNVNLRGPFFL 121 ADV D + +MG +DILVN AGV R ++++ +VN G F Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 122 AQAFARYLREHGRGGRIINNSSVHEELPHPNFTAYCASKGGLKMLMRNIAIELAPLGITV 181 +++ ++Y+ + R G I+ S +P + AY +SK M + + +ELA I Sbjct: 124 SRSVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 182 NNVAPGAVETPINRELMNQPEKLASLLQ--------NIPAGRLGRPHDVAGVVAFLASPD 233 N V+PG+ ET + L +++ IP +L +P D+A V FL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 234 AEYITGTTLVVDGG 247 A +IT L VDGG Sbjct: 243 AGHITMHNLCVDGG 256
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 71.0 bits (174), Expect = 3e-16 Identities = 41/176 (23%), Positives = 74/176 (42%), Gaps = 17/176 (9%) Query: 11 RLLLTGAAGGLGKELRERL-QPYARIIRLSDIAP-------MAPAAGAHEE---VMPCDL 59 + L+TGAAG +G + +RL + +++ + ++ A + DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 60 ADKAAVHALCE--GVDAIAHFGG-VSVERSFEE---ILDANIRGTFHIYEAARLHGIKRV 113 AD+ + L + + ++V S E D+N+ G +I E R + I+ + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 114 VFASSNHVIGFYPQTETLDAHSPRRPDGYYGLSKSYGEDMANFYYDRYGIETVSIR 169 ++ASS+ V G + S P Y +K E MA+ Y YG+ +R Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLR 177
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 28.2 bits (63), Expect = 0.004 Identities = 11/54 (20%), Positives = 22/54 (40%), Gaps = 1/54 (1%) Query: 40 YAWVKRYSKPQAQRQQVDDQQAELRRLRAELKRVTEE-RDILKKAAAYFAKESG 92 A++ ++ + D E+ +L A L++ EE R I + A + Sbjct: 18 KAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKA 71
>cdtoxinb#Cytolethal distending toxin B signature. Length = 269 Score = 28.8 bits (64), Expect = 0.022 Identities = 14/63 (22%), Positives = 26/63 (41%), Gaps = 3/63 (4%) Query: 184 VANGNADAGGLSEVIFNHAVERGLIDPSKVKV-LGYSGEYPQYPWAMRSNLSPELKTKVR 242 +A N DA L E ++N R DP + G++ + P + NL+ ++ Sbjct: 156 IAMRNNDAPALVEEVYNFF--RDSRDPVHQALNWMILGDFNREPADLEMNLTVPVRRASE 213 Query: 243 DVF 245 + Sbjct: 214 IIS 216
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 79.5 bits (196), Expect = 4e-18 Identities = 80/417 (19%), Positives = 133/417 (31%), Gaps = 119/417 (28%) Query: 221 RLVDLIPATGISIQQLNRDINELPRNIPAPAADAA------RVCILDSGINGNHPLLKPA 274 R V +IP I +Q +I I APA +V +LD+G + +HP LK Sbjct: 3 RKVHIIPYQVIKQEQQVNEIPRGVEMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKAR 62 Query: 275 MAESASFVDEEGDD-----DQAGHGTAVAGVALYGDVEACNNSNFWR----PELWIFNGK 325 + +F D++ D D GHGT VAG A + PE + K Sbjct: 63 IIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTI------AATENENGVVGVAPEADLLIIK 116 Query: 326 VMKKCPHTGDAIYDELSLEASLTKAVEYFVELGCRIFNLSLGNNNAPYDGAHVRGLAYIL 385 V+ + + + + Y +E I ++SLG V L + Sbjct: 117 VL------NKQGSGQYD---WIIQGIYYAIEQKVDIISMSLGG------PEDVPELHEAV 161 Query: 386 DVLSRRHNILFVVSTGNFRGSEEPPVPVNSWRDEYPEYLVAEQSAIIDPAPAMMVLTVGS 445 + IL + + GN E + YP V++VG+ Sbjct: 162 K-KAVASQILVMCAAGN-----EGDGDDRTDELGYP-------------GCYNEVISVGA 202 Query: 446 ISRHNATFDSQKYPDISQLSPASENQPSPFTRHGPSVKGALKPELVAAGGNLASPMRQAN 505 I+ + S F+ V +LVA G ++ S Sbjct: 203 IN--------------------FDRHASEFSNSNNEV------DLVAPGEDILS------ 230 Query: 506 AQWSPHMRGLGVLTLNHQWAGNTIFKEVSGTSFAAPYITHLAGRLLNEYPTA-----SAN 560 T+ + SGTS A P++ + + + Sbjct: 231 -------------TVPGGK-----YATFSGTSMATPHVAGALALIKQLANASFERDLTEP 272 Query: 561 MLRAMLVNQAYLPGEVISTFSNEFRKGYKEAKATRKRDVAR---DVAGYGVVSEADL 614 L A L+ + I ++ +G T +++R G++S A L Sbjct: 273 ELYAQLIKRT------IPLGNSPKMEGNGLLYLTAVEELSRIFDTQRVAGILSTASL 323
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.020 Identities = 26/140 (18%), Positives = 46/140 (32%), Gaps = 9/140 (6%) Query: 208 RDQSYLFYILYIAAFGLYQVSVNGAGVQFLWPDRPWWANAATPLLIGATGLFGCLFTRSF 267 R + ++ +G+Y ++ G G L+ P + + I GL RSF Sbjct: 6 RQANKYYWYCQGIGWGVY--TLTGFGFASLY-GSPKLHSMIFNIAISLMGLVLTHAYRSF 62 Query: 268 LRTAEHSRWMDRLLRLIIGFSVVVMVLALTTDYGLSLRLATALALLFTLAVFAAGILAWL 327 ++ + + L + + VV+ + RL L F A L Sbjct: 63 IKRQGWLKLNMGQIILRVLPACVVIGMVWFVANTSIWRL-----LAFINTKPVAFTLPLA 117 Query: 328 RGMRVARYFII-AWSALLIG 346 + + WS L G Sbjct: 118 LSIIFNVVVVTFMWSLLYFG 137
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1115 bits (2885), Expect = 0.0 Identities = 430/567 (75%), Positives = 486/567 (85%), Gaps = 2/567 (0%) Query: 2 KISRQAYADMFGPTVGDKVRLADTDLWIEVEKDFTTYGEEVKFGGGKVIRDGMGQSQLC- 60 ++SR AYA+MFGPTVGDKVRLADT+L+IEVEKDFTT+GEEVKFGGGKVIRDGMGQSQ+ Sbjct: 4 RMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTR 63 Query: 61 AAEVVDTLITNALILDHWGIVKADVGLKDGRIAAIGKAGNPDIQPDVTIAIGASTEVIAG 120 VDT+ITNALILDHWGIVKAD+GLKDGRIAAIGKAGNPD+QP VTI +G TEVIAG Sbjct: 64 EGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAG 123 Query: 121 EGMILTAGGIDSHIHFICPQQIEEALMSGVTTMIGGGTGPATGTNATTVTPGPWHMAMML 180 EG I+TAGG+DSHIHFICPQQIEEALMSG+T M+GGGTGPA GT ATT TPGPWH+A M+ Sbjct: 124 EGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMI 183 Query: 181 KAADAFPMNIGFTGKGNASLPEPLIEQVRAGAIGLKLHEDWGTTPAAIDNCLSVADQYDV 240 +AADAFPMN+ F GKGNASLP L+E V GA LKLHEDWGTTPAAID CLSVAD+YDV Sbjct: 184 EAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEYDV 243 Query: 241 QVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVLPSSTNPT 300 QV IHTDTLNESGFVE T+ A KGRTIH YHTEGAGGGHAPDII+ CG NV+PSSTNPT Sbjct: 244 QVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPT 303 Query: 301 RPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDS 360 RP+T NT+ EHLDMLMVCHHL P+I ED+AFAESRIR+ETIAAEDILHD+GAFS+ISSDS Sbjct: 304 RPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDS 363 Query: 361 QAMGRVGEVITRTWQTADKMKKQRGALPGDGAGNDNFRAKRYIAKYTINPAITHGVSHEV 420 QAMGRVGEV RTWQTADKMK+QRG L + NDNFR KRYIAKYTINPAI HG+SHE+ Sbjct: 364 QAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSHEI 423 Query: 421 GSIEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASFG 480 GS+EVGK ADLVLW PAFFGVKP ++L GG IAA+ MGD NASIPTPQPVHYRPMF ++G Sbjct: 424 GSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGAYG 483 Query: 481 GSLHASSFTFISQAAFEAGVPEQLGLKKKIGVVKGCR-SVQKKDLIHNDYTPDIQVDPQN 539 S SS TF+SQA+ +AG+ +LG+ K++ V+ R + K +IHN TP I+VDP+ Sbjct: 484 RSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDPET 543 Query: 540 YQVRADGQLLWCEPAEVLPMAQRYFLF 566 Y+VRADG+LL CEPA VLPMAQRYFLF Sbjct: 544 YEVRADGELLTCEPATVLPMAQRYFLF 570
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 40.7 bits (95), Expect = 5e-07 Identities = 14/60 (23%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Query: 79 RHTVENSVYVSPDHRGSGIGRSLMKALIERARVLEKHVMVAFIESENRASVHMHQQLGFI 138 +E+ + V+ D+R G+G +L+ IE A+ ++ + N ++ H + + FI Sbjct: 89 YALIED-IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.2 bits (216), Expect = 5e-22 Identities = 39/117 (33%), Positives = 62/117 (52%) Query: 2 KLLVAEDEPKTGTYLQQGLSEAGFTVDRVENGTDAAQHALHTTYDLLILDVMMPGLDGWQ 61 +LVA+D+ T L Q LS AG+ V N + DL++ DV+MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLQKVRAAGNEVPVLFLTARDGVQDRVKGLELGADDYLIKPFAFSELLARIRTLLRR 118 +L +++ A ++PVL ++A++ +K E GA DYL KPF +EL+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 33.5 bits (76), Expect = 0.002 Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 18/116 (15%) Query: 156 PLVIDAKDPE-----PFSYDRDYVVMLTDWSDEDPARILSKLKKQSDYYNFHKRTVG--D 208 PL+I K P+ P+ D ++ +I+ + + Y V D Sbjct: 194 PLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLD 253 Query: 209 FINDVSE-DGWAATIANRKMWAQMKMSPTDLADVSGYT---YT----YLMNGQAPD 256 F +DVS+ D W N W+ K++P +LADV+ Y YT YL++ + Sbjct: 254 FKDDVSKGDLWGK--ENYSDWSN-KLTPNELADVNDYMRGGYTAINNYLISNGPLN 306
>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature. Length = 393 Score = 31.1 bits (70), Expect = 0.006 Identities = 13/25 (52%), Positives = 15/25 (60%), Gaps = 1/25 (4%) Query: 280 EVGLRLRYEIVREFAPYIGVTWSRA 304 + L L Y + F PYIGV WSRA Sbjct: 272 QASLALSYRL-NMFTPYIGVKWSRA 295
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 62.0 bits (150), Expect = 1e-13 Identities = 43/169 (25%), Positives = 70/169 (41%), Gaps = 4/169 (2%) Query: 43 KTFVITGASSGFGRGVALKLAALQGDVVLAARRTDVLEELAAQIRMAGGSALVVTTDVSN 102 K ITGA+ G G VA LA+ + + LE++ + ++ A DV + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 103 PNEMQDLARAAIERFGRIDVWINNAAVGALGRFEDVPVEDHARIVDVNLKGMIYGSHAAM 162 + ++ G ID+ +N A V G + E+ VN G+ S + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 163 RQFRAQGFGTLVNVGSVESEIPL----AYHASSAATKGGVINLGAAIAE 207 + + G++V VGS + +P AY +S AA LG +AE Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE 177
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 673 bits (1737), Expect = 0.0 Identities = 196/1057 (18%), Positives = 420/1057 (39%), Gaps = 50/1057 (4%) Query: 5 IIRWSVANRFLILLATVFAVAWGVWSVKNTAVDALPDLSDVQVIIRTPYPGQAPRIVENQ 64 + + + + + + G ++ V P ++ V + YPG + V++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 VTYPLTTTMLSVPGAKTVRGYSF-FGDSYVYVLFEDGTDLYWARSRVLEYLSQVQSRLPA 123 VT + M + + S G + + F+ GTD A+ +V L LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 124 AAK-PALGPDATGVGWIYQYALVDRTGKHDLSQLRSLQDWFLRYELKTLPNVAEVAPIGG 182 + + + + ++ V + ++ L L V +V G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 183 MVKQYQVVLDPVRMASRGVTQQQIAKAIDEANRETGGSVLELAET------EFMVRATGY 236 ++ LD + +T + + N + L + A Sbjct: 181 Q-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 237 LKTLKDFRAIPLRLDG-GVPVTLGDVAHIQLGPEMRRGISELDGEGEVVGGVVILRSGKN 295 K ++F + LR++ G V L DVA ++LG E I+ ++G+ G + L +G N Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLATGAN 298 Query: 296 ARETIAAVQTKLDELKASLPQGVEIVTTYDRSKLIDSAVENLTHKLIEEFIVVALVCAIF 355 A +T A++ KL EL+ PQG++++ YD + + ++ + L E ++V LV +F Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 356 LWHLRSSLVAIVSLPIGILIAFVIMQRQGINANIMSLGGIAIAIGAMVDAAIVMIENAHK 415 L ++R++L+ +++P+ +L F I+ G + N +++ G+ +AIG +VD AIV++EN + Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 416 HIEAWHKRHPDSTLKGQEHWKVITDAAVEVGPALFFSLLIITLSFIPVFTLEAQEGRLFG 475 + + + ++ AL ++++ FIP+ G ++ Sbjct: 419 VMME----------DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYR 468 Query: 476 PLAFTKTYAMAAAAGLSVTLVPVLMGYWIRGKIPDEHRNP------LNRGLIWI---YKP 526 + T AMA + +++ L P L ++ + H N N Y Sbjct: 469 QFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTN 528 Query: 527 ALDAVLRWPKMTLLVAVLVFLTGLWPASRLGGEFLPPLDEGDLLYMPTALPGLSAQKASE 586 ++ +L LL+ L+ + RL FLP D+G L M G + ++ + Sbjct: 529 SVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQK 588 Query: 587 LLQQTDRLIKT--VPEVAHVFGKAGRADTATDPAPLEMFETTIQFKPKDQW-RPGMTPDK 643 +L Q V VF G + + KP ++ + + Sbjct: 589 VLDQVTDYYLKNEKANVESVFTVNGF---SFSGQAQNAGMAFVSLKPWEERNGDENSAEA 645 Query: 644 LVEELDRTVQVPGLANLWIPPIRNRIDMLATGIKSPIGVKVYGTDLAQIDKATQAVEKIA 703 ++ + + + +++ + G + +A + +A Sbjct: 646 VIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMA 705 Query: 704 KTVPG-VSSALAERLTGGRYIDVDIDRVAAARYGLNIADVQSIVAGAIGGQTIGETVEGL 762 P + S L +++D+ A G++++D+ ++ A+GG + + ++ Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 763 ARYPINLRYGREWRDSISDLRNLPIYTPQGSQITLGTVAKVQVTDGPPMLKSENARLSGW 822 + ++ ++R D+ L + + G + G P L+ N S Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPS-- 823 Query: 823 VYVDVRGRDMA-AVVGDLREKISK-GVQLESGMSISYSGQFEFMERANAKLKLVVPATLL 880 ++++G GD + +L +G+ ++G + + +V + + Sbjct: 824 --MEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFV 881 Query: 881 IIFVLLYLTFGRFGEALLIMATLPFALTGGVWFLYLLGYNLSVATGIGFIALAGVSAEFG 940 ++F+ L + + + +M +P + G + L V +G + G+SA+ Sbjct: 882 VVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNA 941 Query: 941 VIMLLYLKNAWTDRVNAGAHGEGVLLDAIREGAVQRVRPKAMTVAVIIAGLLPILWGSGT 1000 ++++ + K+ G+G +++A R+RP MT I G+LP+ +G Sbjct: 942 ILIVEFAKDLME------KEGKG-VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGA 994 Query: 1001 GSEIMSRIAAPMVGGMITAPLLSLFVLPAAYLLMRRR 1037 GS + + ++GGM++A LL++F +P ++++RR Sbjct: 995 GSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.1 bits (99), Expect = 4e-06 Identities = 30/138 (21%), Positives = 50/138 (36%), Gaps = 18/138 (13%) Query: 208 TVRSPIGGVLNSLDVR-EGMTVSTGASL-ARVNGLEKVWLEVAVPEAQVANVAPGQLVNA 265 +R+P+ + L V EG V+T +L V + + + V + + GQ Sbjct: 329 VIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAII 388 Query: 266 RLPAFAGE---VLEGTIQAVLPQANLDSRT-----VRVRVELPNPQQ-----RLRPGMTA 312 ++ AF L G ++ + A D R V + +E L GM Sbjct: 389 KVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAV 448 Query: 313 EV---TLSRNVEDVLVIP 327 T R+V L+ P Sbjct: 449 TAEIKTGMRSVISYLLSP 466
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 27.5 bits (61), Expect = 0.043 Identities = 21/71 (29%), Positives = 34/71 (47%) Query: 24 RQLMQNLRLQGKTPRPDDARTLMTRNLGLAGAADYFGAQLSNSELASLESDLFTELASVR 83 RQ Q LR +G P D + G G + +LS S+LA L L T +A+ Sbjct: 26 RQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRKIRLSTSDLALLTRQLATLVAASM 85 Query: 84 LFDDALESLNQ 94 ++AL+++ + Sbjct: 86 PLEEALDAVAK 96
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 1e-20 Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 4/135 (2%) Query: 2 RILVVEDEIKAAEYLQQGLIECGYLVDCVSDGLDGFHLALQNDYDIVLLDVNLPTMDGWE 61 ILV +D+ L Q L GY V S+ + D D+V+ DV +P + ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLELIR-RRKQTRVIMLTANGRLEQKVRGLESGADDYLVKPFQFPELLARIRTLL---RR 117 +L I+ R V++++A ++ E GA DYL KPF EL+ I L +R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 118 GEAVTLPSNLRVADL 132 + + L Sbjct: 125 RPSKLEDDSQDGMPL 139
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.8 bits (119), Expect = 1e-08 Identities = 35/211 (16%), Positives = 71/211 (33%), Gaps = 31/211 (14%) Query: 171 ASTDLSERRSEFYAAQKRLALAQKTYRREKELWEERISAEQDYLQAQQALREAELTVANA 230 A +L +S+ + + A++ Y+ +L++ I + L EL Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE 323 Query: 231 NAQLQALGSDAGKPDALSRYELRAPFDGMIVEKDI-TLGESVNTDDQIFIIS-DLSTVWA 288 +RAP + + + T G V T + + +I + T+ Sbjct: 324 R---------------QQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEV 368 Query: 289 DISVPANALSAVRVGSNAVIEATAFESSA----NGTVSYVG--SLVGQQSRAAT-ARVTL 341 V + + VG NA+I+ AF + G V + ++ Q+ +++ Sbjct: 369 TALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISI 428 Query: 342 PNPEGV-------WRPGLFVKVQVGAGEASV 365 G+ V ++ G SV Sbjct: 429 EENCLSTGNKNIPLSSGMAVTAEIKTGMRSV 459 Score = 44.8 bits (106), Expect = 5e-07 Identities = 36/204 (17%), Positives = 74/204 (36%), Gaps = 36/204 (17%) Query: 80 AEKDEHEDEPEGAEHTET----AEVELSETQILAAGISLATAQPAKIKSAIELPGEITFN 135 EKDE+E P E ET ++ + I+ + +++ G++T + Sbjct: 34 REKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHS 93 Query: 136 QDRTAQVVPRLSGVVEAVKVDLGEQVKQGQVLAVIASTDLSERRSEFYAAQKRLALAQKT 195 R+ ++ P + +V+ + V GE V++G VL + + ++ Q L A+ Sbjct: 94 -GRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGA---EADTLKTQSSLLQARLE 149 Query: 196 YRR----------------------------EKELWEERISAEQDYLQAQQALREAELTV 227 R E+E+ ++ + Q + EL + Sbjct: 150 QTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNL 209 Query: 228 ANANAQLQALGSDAGKPDALSRYE 251 A+ + + + + LSR E Sbjct: 210 DKKRAERLTVLARINRYENLSRVE 233
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 801 bits (2070), Expect = 0.0 Identities = 226/1062 (21%), Positives = 448/1062 (42%), Gaps = 58/1062 (5%) Query: 5 IIRFSIEHRWLVMLAVLGMAALGAYSYQKLPIDAVPDITNVQVQINTAAPGYSPLEVEQR 64 + F I + + + GA + +LP+ P I V ++ PG V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 ITYPLETVMAGLPKLEQTRSLS-RYGLSQITVIFEEGTDIYFARQLVNERLGGAKDQLPD 123 +T +E M G+ L S S G IT+ F+ GTD A+ V +L A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 124 GVTPTLGPISTGLGEIYFWTVEAEEGATKSDGTPYTPADLREIQDWIIKPQVRNVPGVTE 183 V + Y SD T D+ + +K + + GV + Sbjct: 121 EVQQQGISVEKSSS-SYLMVA-----GFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGD 174 Query: 184 INTIGGYAKEYQIAPNPDTLRSFGLTLQDLIEAVEQNNNNLGAGYI------EKRGEQYL 237 + G +I + D L + LT D+I ++ N+ + AG + + Sbjct: 175 VQLFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS 233 Query: 238 VRAPGQMQSVEDIRDTLI-SNVDGTPVRIRDVATVEVGKELRTGAATENGREVVLGTAFM 296 + A + ++ E+ + N DG+ VR++DVA VE+G E A NG+ + Sbjct: 234 IIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKL 293 Query: 297 LIGENSRVVSRAVDDKMKEINLSLPEGVKAITVYDRTVLVDKAISTVKKNLTEGAILVVV 356 G N+ ++A+ K+ E+ P+G+K + YD T V +I V K L E +LV + Sbjct: 294 ATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFL 353 Query: 357 ILFLFLGNIRAAILTALVIPLSMLFTFTGMVANQVSANLMSLG--ALDFGIIIDGAVVIV 414 +++LFL N+RA ++ + +P+ +L TF + A S N +++ L G+++D A+V+V Sbjct: 354 VMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVV 413 Query: 415 ENCVRRLAHAQSHHGRALTLSERLHEVFAAAKEVRRPLLYGQLIIMIVYLPIFALTGVEG 474 EN R + + + +++ L+ +++ V++P+ G G Sbjct: 414 ENVERVMMEDK---------LPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 475 KMFTPMAFTVVTALFGAIILSVTFVPAAVALFIGKRVTE----KENFL------IRNAKR 524 ++ + T+V+A+ ++++++ PA A + E K F ++ Sbjct: 465 AIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVN 524 Query: 525 AYAPALDAVMANKPAVLTFAVVVVILSGLVGSRMGSEFVPSLNEGDFAIQALRVPATSLS 584 Y ++ ++ + L ++V ++ R+ S F+P ++G F + +++PA + Sbjct: 525 HYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVF-LTMIQLPAGATQ 583 Query: 585 QSVE--MQQQLERKLMDEFPEIERIFARTGTAEVASDAMPPNISDGYVMLKPQEQWPDPG 642 + + + Q + L +E +E +F G + N +V LKP E+ Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNG---FSFSGQAQNAGMAFVSLKPWEERNGDE 640 Query: 643 KSRNQLLSEVQASAAELP-GNNYEFSQPIQLRFNELISGVRAAVA-VKIYGDDMDVLNST 700 S ++ + ++ G F+ P EL + + G D L Sbjct: 641 NSAEAVIHRAKMELGKIRDGFVIPFNMP---AIVELGTATGFDFELIDQAGLGHDALTQA 697 Query: 701 AAEVSEVLGQVPGA-SEVTVEQTTGLPMLTIDIDRDQIARYGLSLDTVQQAVAVAIGGRE 759 ++ + Q P + V +++D+++ G+SL + Q ++ A+GG Sbjct: 698 RNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTY 757 Query: 760 AGTLFQGDRRFDIVVRLPDEIRSDLAAIERLPIALPRELNSTISYIPLGEVATLDLAPGP 819 R + V+ + R +++L + ++ +P T G Sbjct: 758 VNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVR-----SANGEMVPFSAFTTSHWVYGS 812 Query: 820 NQISREEGKRRIVVSANVRGRDIGSFVSEAEQKIQAQVD-IPAGYWIDWGGTFEQLESAT 878 ++ R G + + G+ +A ++ +PAG DW G Q + Sbjct: 813 PRLERYNGLPSMEIQGEAAP---GTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSG 869 Query: 879 KRLQIVVPVALLLVFILLFMMFNNVKDGLLVFTGIPFALTGGIVALWLRDIPLSISAGVG 938 + +V ++ ++VF+ L ++ + + V +P + G ++A L + + VG Sbjct: 870 NQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVG 929 Query: 939 FIALSGVAVLNGLVMISFIRSLRE-QGLPLDTAIREGALTRLRPVLMTALVASLGFVPMA 997 + G++ N ++++ F + L E +G + A RLRP+LMT+L LG +P+A Sbjct: 930 LLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLA 989 Query: 998 LNVGTGAEVQRPLATVVIGGILSSTVLTLLVLPLLYQMAHRR 1039 ++ G G+ Q + V+GG++S+T+L + +P+ + + R Sbjct: 990 ISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Score = 90.7 bits (225), Expect = 2e-20 Identities = 69/524 (13%), Positives = 160/524 (30%), Gaps = 40/524 (7%) Query: 2 FERIIRFSIEHRWLVMLAVLGMAALGAYSYQKLPIDAVPDITNVQVQINTAAPGYSPLEV 61 + + + +L + A + +LP +P+ P + E Sbjct: 526 YTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQER 585 Query: 62 EQRITYPLETVMAGLPKLEQTRSLSRYG-----------LSQITV-IFEEGTDIYFARQL 109 Q++ + K + G ++ +++ +EE + + Sbjct: 586 TQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEA 645 Query: 110 VNERLGGAKDQLPDGVT-PTLGPISTGLGEIYFWTVEAEEGATKSDGTPYTPADLREIQD 168 V R ++ DG P P LG D L + ++ Sbjct: 646 VIHRAKMELGKIRDGFVIPFNMPAIVELG------TATGFDFELIDQAGLGHDALTQARN 699 Query: 169 WIIKPQVRNVPGVTEINTIGGY-AKEYQIAPNPDTLRSFGLTLQDLIEAVEQNNNNLGAG 227 ++ ++ + + G ++++ + + ++ G++L D+ + + Sbjct: 700 QLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVN 759 Query: 228 YIEKRGEQY--LVRAPGQM-QSVEDIRDTLISNVDGTPVRIRDVATVEVGKELRTGAATE 284 RG V+A + ED+ + + +G V T + Sbjct: 760 DFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVY-----GSPR 814 Query: 285 NGREVVLGTAFMLIGENSRVVSRAVDDKMKEINLSLPEGVKAITVYDRTVLVDKAISTVK 344 R L + + S M+ + LP G+ + + + Sbjct: 815 LERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGI-GYDWTGMSYQERLSGNQAP 873 Query: 345 KNLTEGAILVVVILFLFLGNIRAAILTALVIPLSMLFTFTGMVANQVSANLMSLGAL--D 402 + ++V + L + + LV+PL ++ ++ + L Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTT 933 Query: 403 FGIIIDGAVVIVENCVRRLAHAQSHHGRALTLSERLHEVFAAAKEVRRPLLYGQLIIMIV 462 G+ A++IVE G+ + + A + RP+L L ++ Sbjct: 934 IGLSAKNAILIVE----FAKDLMEKEGKGV-----VEATLMAVRMRLRPILMTSLAFILG 984 Query: 463 YLPIFALTGVEGKMFTPMAFTVVTALFGAIILSVTFVPAAVALF 506 LP+ G + V+ + A +L++ FVP + Sbjct: 985 VLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.8 bits (67), Expect = 0.014 Identities = 38/208 (18%), Positives = 77/208 (37%), Gaps = 20/208 (9%) Query: 40 SLSLIADALHNLSDAASLVIALIARKIGRKPPDAFKTFGYRRSETIAALINLVTLIIVGL 99 ++ + A+ L D A +V+ + R + + K + I + + +++ + Sbjct: 394 TMFGMVLAIGLLVDDAIVVVENVERVM-MEDKLPPKEATEKSMSQIQGALVGIAMVLSAV 452 Query: 100 YL----IYEAIGRFFAPQPIEGWTVVVVAGIALIVDV-VTALLTYTM----SKNSMNIKA 150 ++ + G + I T+V ++++V + +T L T+ S K Sbjct: 453 FIPMAFFGGSTGAIYRQFSI---TIVSAMALSVLVALILTPALCATLLKPVSAEHHENKG 509 Query: 151 AFLHNVSDAL-ASVGVIIAGTLILLYDWYWTDTVLTLMIAG-YVLWQ--GFSMLP---KT 203 F + SV +L + L++AG VL+ S LP + Sbjct: 510 GFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQG 569 Query: 204 IHLLMEGAPEGVSITDIINVMEQVDDVV 231 + L M P G + V++QV D Sbjct: 570 VFLTMIQLPAGATQERTQKVLDQVTDYY 597
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 106 bits (265), Expect = 1e-29 Identities = 64/235 (27%), Positives = 112/235 (47%), Gaps = 15/235 (6%) Query: 9 KVFDRKLVVITGGCAGIGRALAVRMAQAGARLVIFDLQQDALDGLVQHL-ADHHNAEALG 67 K + K+ ITG GIG A+A +A GA + D + L+ +V L A+ +AEA Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 68 LCCDVSDAEAVQRAIALVVERFGGIDVLINNAGITHRSPVASTSLAVFQRVMAVNFYGAL 127 DV D+ A+ A + G ID+L+N AG+ + S S ++ +VN G Sbjct: 64 A--DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 128 HCTQAALPSLIA-RNGQVIVLSSLSQYAPVPNRAAYNASKHALHGLFETLRGELSDTEVS 186 + +++ ++ R+G ++ + S P + AAY +SK A + L EL++ + Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 187 VMLVCPGYTATDLRK----------HVLVGDGSTAPSPVLDIGRVASAQDVAEAI 231 +V PG T TD++ V+ G T + + + ++A D+A+A+ Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGI-PLKKLAKPSDIADAV 235
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 28.8 bits (64), Expect = 0.017 Identities = 9/22 (40%), Positives = 12/22 (54%) Query: 216 LQRKACCQHFRRADGELCDSCP 237 L R+ CCQ +R D + C C Sbjct: 239 LVRRTCCQRYRLPDVQQCGDCT 260
>PF04183#IucA / IucC family Length = 580 Score = 579 bits (1495), Expect = 0.0 Identities = 163/583 (27%), Positives = 283/583 (48%), Gaps = 18/583 (3%) Query: 19 LQAEHWARANRLLVKKALAEFSHEKLLSPEPLGDSHYRVAVPDSSTEYRFKARRLALDHW 78 + + W NR LV K L+E +E++ E GD Y + +P + ++RF A R Sbjct: 1 MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGA--QWRFIAERGIWGWL 58 Query: 79 SIVTDSIEKLGDGQPQPLDALSFIIEFADTLGISENNLPVYLDEISSTLFGSAYKLANS- 137 I ++ +P+ A + +++ L +S+ + ++ ++ +TL G L Sbjct: 59 WIDAQTLRC----ADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARR 114 Query: 138 PLSAAQLALADFQQIETGMREGHPGFVANNGRMGFDAQDYRAYAPEAASPVRLVWLAVHR 197 LSA+ L + +++ + GHP FV N GR G+ + YAPE A+ RL WLAV R Sbjct: 115 GLSASDLINLNADRLQ-CLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKR 173 Query: 198 SRASYSAIDGLDQPTLLREELGGQLDVFHNQLHALQLAPDDYLLMPAHPWQWHNILAIGF 257 + + +D LL + Q +Q+ ++L +P HPWQW +A F Sbjct: 174 EHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDF 233 Query: 258 AAEIANRQIVYLGLSNDRYLAQQSIRTFFNQSQPQRRYVKTALSILNMGFMRGLSPYYMQ 317 A+ A ++V LG D++LAQQS+RT N S+ +K L+I N RG+ Y+ Sbjct: 234 IADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIA 293 Query: 318 ATPAINTYLAERVASDPLLRDCGFQLLREVAAIGYRNPYYEQALPASSPYRKMLSALWRE 377 A P + +L + A+D L G +L E AA + Y A Y++ML +WRE Sbjct: 294 AGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRE 353 Query: 378 SPYGHIQSGQRLMTMAALLHSDGEERALLATLISASGLTADRWVRRYLDAYLTPLLHCFY 437 +P ++ + + MA L+ D + L I SGL A+ W+ + + PL H Sbjct: 354 NPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLC 413 Query: 438 AHDLVFMPHGENLILVLEDHVPVRVLMKDIGEEAVILDAD----AQIPEAVGRLAVSVPD 493 + + + HG+N+ L +++ VP RVL+KD + ++ + +P+ V + + Sbjct: 414 RYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSA 473 Query: 494 ELKVLSIFTDVFDGFFRYLGQILDEQVGLPEQRFWQQVADCIADYQACQPQLRDKFARYD 553 + + + T F R++ ++ ++G+PE+RF+Q +A ++DY PQ+ ++FA + Sbjct: 474 DYLIHDLQTGHFVTVLRFISPLMV-RLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFS 532 Query: 554 LFAEEFARSCLNRLQLGNNRQMLDLADPAGAL-KFAGTLKNPV 595 LF + R LN ++L DL + L + L+NP+ Sbjct: 533 LFRPQIIRVVLNPVKL----TWPDLDGGSRMLPNYLEDLQNPL 571
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.0 bits (83), Expect = 2e-04 Identities = 49/267 (18%), Positives = 89/267 (33%), Gaps = 7/267 (2%) Query: 7 LIGMTLLAVLGDSLLMPFYPQYFTERFG-ELRSEQVGLYLAAVCLVAMLALPLWVRLSRH 65 ++ L +G L+MP P + + G+ LA L+ P+ LS Sbjct: 10 ILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDR 69 Query: 66 AHPLRLLIFGQLMAGLLALACAAIEQQWLFWPVSLTMIAFKASYLLMYPYVMGLVGADQQ 125 +L+ A + A W+ + + A+ + Y+ + D++ Sbjct: 70 FGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDER 129 Query: 126 VRTIGLLSVVVHLGAIAGATLGGGVLHYLSPARMFVLMGLMDFVQMAVSLLLLRHAPQPT 185 R G +S G +AG L GG++ SP F ++ + LL + + Sbjct: 130 ARHFGFMSACFGFGMVAGPVL-GGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGE 188 Query: 186 RVDASTPPRPRGEHLAIARL---CLLMLAFYFCIYLARPFFTVYWEQLGGPQASWITGLV 242 R AR ++A +F + L W G + W + Sbjct: 189 RRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTI 248 Query: 243 -YAIPGMLALLALALHYHAGQRLTAWL 268 ++ L +LA G + A L Sbjct: 249 GISLAAFGILHSLAQAMITG-PVAARL 274
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.9 bits (153), Expect = 5e-13 Identities = 37/187 (19%), Positives = 60/187 (32%), Gaps = 29/187 (15%) Query: 2 IKVFIVDDSALVRQVLTACLDSHPGIQVIGQAADPLFALEKMQRDWPDVLVLDVEMPRMD 61 + + DD A +R VL L S G V ++ + D++V DV MP + Sbjct: 4 ATILVADDDAAIRTVLNQAL-SRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GITFLRKIMAERP-TPAIICSTLTEAGAAITLEALAAGAVGVFTKARLGLKESLQQLSSE 120 L +I RP P ++ S AI +A GA K Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAI--KASEKGAYDYLPKP-------------- 105 Query: 121 LIRQIEQAARSRPRAAVRAQAKPSSPSREPSPAAGLTTTDRVIALGTSTGGTQALELVLR 180 + + RA + +PS + L +G S + ++ R Sbjct: 106 --FDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPL--------VGRSAAMQEIYRVLAR 155 Query: 181 QLPADSP 187 + D Sbjct: 156 LMQTDLT 162
>PF06580#Sensor histidine kinase Length = 349 Score = 45.6 bits (108), Expect = 4e-07 Identities = 17/91 (18%), Positives = 30/91 (32%), Gaps = 11/91 (12%) Query: 419 QLGKDIRLEIQGADTELDKAVIDRLADPLTHLVRNAIDHGIEPAEQRLAAGKPAEGHLRL 478 Q ++ E Q + + + + + LV N I HGI P G + L Sbjct: 235 QFEDRLQFENQ-INPAIMDVQVPPML--VQTLVENGIKHGIAQ--------LPQGGKILL 283 Query: 479 DAYHESGMIVIEVADDGRGLNTQRIREKAIA 509 ++G + +EV + G Sbjct: 284 KGTKDNGTVTLEVENTGSLALKNTKESTGTG 314
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.005 Identities = 30/198 (15%), Positives = 51/198 (25%), Gaps = 48/198 (24%) Query: 59 QLSALVSRAMQQNHDVRLAMARVTAARAQ--LRQSRAGLLPSFDLPGSASRQWNENDQEA 116 +L+AL + A L AR+ R Q R LP L Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKL--------------- 170 Query: 117 EPDSPLADLIPDDDVISFDTWELALQATWELDLFGATRARRDSAARQLRSAEAQTVAARL 176 PD P + +++V+ Q + + Q L Sbjct: 171 -PDEPYFQNVSEEEVL----------------------RLTSLIKEQFSTWQNQKYQKEL 207 Query: 177 AVASNTAQGYLQLRALQGQRALLVEGIEVARELERIAGL--LFHAGEVTRLDVEATSAER 234 + A+ L + L E R+ L H + + V + Sbjct: 208 NLDKKRAERLTVLARINRYENLS------RVEKSRLDDFSSLLHKQAIAKHAVLEQENKY 261 Query: 235 ASLEADLDELDIHLAEAQ 252 +L L + + Sbjct: 262 VEAVNELRVYKSQLEQIE 279
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 444 bits (1144), Expect = e-141 Identities = 214/1052 (20%), Positives = 422/1052 (40%), Gaps = 71/1052 (6%) Query: 4 ARYSITRPVNIWILVLICLFGGILAFFEIGRLEDPEFTIKQAIVNVQYPGATALEVEQQV 63 A + I RP+ W+L +I + G LA ++ + P V+ YPGA A V+ V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 TEPLESAIQQMSQIKEIRSRSMP-GIAEIRVEMQDRYAGDALPQIWDELRNKINDAQGDL 122 T+ +E + + + + S S G I + Q G +++NK+ A L Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQS---GTDPDIAQVQVQNKLQLATPLL 118 Query: 123 PPGIEPPQV-NDDFGDVYGIFYALTGDG--LTLKELHETAKD-LRRALLTADGVGKVEIA 178 P ++ + + Y + D T ++ + ++ L +GVG V++ Sbjct: 119 PQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLF 178 Query: 179 GVQEERILVEVDQAQLAALGVAPDEIAAALADTDAAVDAGGVNAG------EFFVRLRPS 232 G + + + +D L + P ++ L + + AG + + + Sbjct: 179 G-AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQ 237 Query: 233 GAFDSLEELRALPV--GQGPQRVELGAIARLSREYAERPQQIIRHNGQQALTLGISGVSG 290 F + EE + + V L +AR+ E I R NG+ A LGI +G Sbjct: 238 TRFKNPEEFGKVTLRVNSDGSVVRLKDVARV-ELGGENYNVIARINGKPAAGLGIKLATG 296 Query: 291 ANIVEVGHSVEAVLQANEHRMPLGADLHPLYEQHQIVDESVNSFALNVFLSVAIVVGVLC 350 AN ++ +++A L + P G + Y+ V S++ +F ++ +V V+ Sbjct: 297 ANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMY 356 Query: 351 IAMG-LRAGFIIGAVLFLTVLGTLLVMWLVGIELERISLGALIIAMGMLVDNAVVVCDGM 409 + + +RA I + + +LGT ++ G + +++ +++A+G+LVD+A+VV + + Sbjct: 357 LFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENV 416 Query: 410 L-VRQRQGKSILEASQQTLRQTQWPLLGATIIGILAFAGIGLSQDTTGELLFSLFFVIAV 468 V EA+++++ Q Q L+G ++ F + +TG + I Sbjct: 417 ERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVS 476 Query: 469 SLLLSWLLALLLVPLFGHYLLRNADTDEDPDAAYNGPWYNR--------YRRLAGGVLHR 520 ++ LS L+AL+L P LL+ + + W+N Y G +L Sbjct: 477 AMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGS 536 Query: 521 PWLTIGVLLVLTVVSAVIFTRLPQSFFPPSSTPLFYVNLFLPQGTHIRDTARTASDVEEY 580 + + ++ V+F RLP SF P +F + LP G T + V +Y Sbjct: 537 TGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDY 596 Query: 581 L--AEMEGVSGVSSFIGAGASRFMLTYMPEQPNSSLMHFLV-----RTEDAELIDRLVRQ 633 E V V + G ++ + N+ + + R D + ++ + Sbjct: 597 YLKNEKANVESVFTVNG-------FSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHR 649 Query: 634 INQELPQRYPSADVTAAQFMFGPNAEAKLEARISGPDIEVLRAISAEGRKRLQDEGKVF- 692 EL + F+ N A +E + L + G L Sbjct: 650 AKMELGKIRDG-------FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLL 702 Query: 693 -----------NVRDDWRQPVLVLRPQLALDRLADAGLTRQAVARALAAGSEGQRVSLLR 741 +VR + + + ++ ++ G++ + + ++ G V+ Sbjct: 703 GMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFI 762 Query: 742 ERDELIPVLLRAAPEDRVSSDDLLQRLIWSPAGNGYVPLAQVADGIEPTSEDSIIVRYDR 801 +R + + ++A + R+ +D+ + + S G VP + + RY+ Sbjct: 763 DRGRVKKLYVQADAKFRMLPEDVDKLYVRSANG-EMVPFSAFTT-SHWVYGSPRLERYNG 820 Query: 802 ERTISIRAEPRDGENTNEAHQRIRPLIEGIELPVNYSLKWGGDYEQSSDAQQALASTLAV 861 ++ I+ E G ++ +A + L +LP W G Q + + +A+ Sbjct: 821 LPSMEIQGEAAPGTSSGDAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAI 878 Query: 862 PYLAMVLVTVLLFARVRQPLMIWLVVPMAICGVSFGLLLTGQAFGFMALLGLLSLTGMLI 921 ++ + L L+ P+ + LVVP+ I GV L Q ++GLL+ G+ Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 922 KNAVVLVDEI-DRQIDDEVPRLTAIIEASASRLRPVMMAAGTTVLGMVPLLFDP-----F 975 KNA+++V+ D + + A + A RLRP++M + +LG++PL Sbjct: 939 KNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGA 998 Query: 976 FANMAVTIMGGLGFATLLTLLAVPCLYLLFMK 1007 + + +MGG+ ATLL + VP +++ + Sbjct: 999 QNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 99 bits (249), Expect = 2e-23 Identities = 85/520 (16%), Positives = 193/520 (37%), Gaps = 37/520 (7%) Query: 513 LAGGVLHRPWLTIGVLLVLTVVSAVIFTRLPQSFFPPSSTPLFYVNLFLPQGTHIRDTAR 572 +A + RP + ++L + A+ +LP + +P + P V+ P Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 573 TASDVEEYLAEMEGVSGVSSF-IGAGASRFMLTYMPEQPNSSLMHFLVRTEDAELIDRLV 631 +E+ + ++ + +SS AG+ LT+ + + + + Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDP-----DIAQVQVQNKLQLAT 115 Query: 632 RQINQEL-PQRYPSADVTAAQFMFGPNAEAKLEARISGPDIEVLRAIS-AEGRKRLQDEG 689 + QE+ Q +++ M + DI A + + RL G Sbjct: 116 PLLPQEVQQQGISVEKSSSSYLMVA--GFVSDNPGTTQDDISDYVASNVKDTLSRLNGVG 173 Query: 690 KVFNVRDDWRQPVLVLRPQLALDRLADAGLTRQAVARAL-------AAGSEGQRVSLLRE 742 V + + L L LT V L AAG G +L + Sbjct: 174 DV-QLFGAQYAMRIWLDAD----LLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQ 228 Query: 743 RDELIPVLLRAAPEDRVSSDDLLQRLIWSPAGNGY-VPLAQVADGIEPTSEDSIIVRYDR 801 + + + R + + ++ +G V L VA ++I R + Sbjct: 229 Q-----LNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARING 283 Query: 802 ERTISIRAEPRDGENTNEAHQRIRPLIEGIELPVNYSLKWGGDYEQSSDAQQALASTLAV 861 + + + G N + + I+ + ++ +K Y+ + Q ++ + Sbjct: 284 KPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKT 343 Query: 862 PYLAMVLVTVLLFA---RVRQPLMIWLVVPMAICGVSFGLLLTGQAFGFMALLGLLSLTG 918 + A++LV ++++ +R L+ + VP+ + G L G + + + G++ G Sbjct: 344 LFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIG 403 Query: 919 MLIKNAVVLVDEIDR-QIDDEVPRLTAIIEASASRLRPVMMAAGTTVLGMVPLLF----- 972 +L+ +A+V+V+ ++R ++D++P A ++ + ++ A +P+ F Sbjct: 404 LLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGST 463 Query: 973 DPFFANMAVTIMGGLGFATLLTLLAVPCLYLLFMKVRPEE 1012 + ++TI+ + + L+ L+ P L +K E Sbjct: 464 GAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAE 503
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.1 bits (117), Expect = 2e-08 Identities = 16/86 (18%), Positives = 30/86 (34%) Query: 74 VSGRIERILIDEGTRVRRGQTLAQLDRTDYRLQLREAEARLRQLEADLARKRTLLAEGIL 133 + ++ I++ EG VR+G L +L + ++ L Q + R + L L Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 134 APAAIEALQANTVAARVARDSAQRNI 159 L V+ + R Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLT 188 Score = 36.0 bits (83), Expect = 2e-04 Identities = 20/130 (15%), Positives = 44/130 (33%), Gaps = 9/130 (6%) Query: 80 RILIDEGTRVRRGQTLAQLDRTDYRLQLREAEARLRQLEADLARKRTLLAEGILAPAAIE 139 +L E V L Y+ QL + E+ + + + L IL Sbjct: 253 AVLEQENKYVEAVNELRV-----YKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQT 307 Query: 140 ALQANTVAARVARDSAQRNIDHSTLTAPFDGVVAR-RLAEPDMVVAVGTPVFEM-QDNRH 197 + +A++ ++ S + AP V + ++ VV + + ++ Sbjct: 308 TDNIGLLTLELAKNEERQQ--ASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT 365 Query: 198 IEVSVDLPES 207 +EV+ + Sbjct: 366 LEVTALVQNK 375
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 36.0 bits (83), Expect = 2e-05 Identities = 22/114 (19%), Positives = 46/114 (40%), Gaps = 14/114 (12%) Query: 37 FSKLYERINHEMEEETQHADALLQRILFLEGTP-----------DMTPEPIHPGHTVPDM 85 F L+E+ + + D + +R+L + G P +T + +M Sbjct: 43 FFTLHEKFEELYDHAAETVDTIAERLLAIGGQPVATVKEYTEHASITDGGNET--SASEM 100 Query: 86 LRSDLALEYKVRAALAQGIALAEQHGDYPTRDMLALQLHDTEEDHAYWLEQQLG 139 +++ + ++ + I LAE++ D T D+ + L + E + L LG Sbjct: 101 VQALVNDYKQISSESKFVIGLAEENQDNATADLF-VGLIEEVEKQVWMLSSYLG 153
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.3 bits (71), Expect = 0.013 Identities = 26/225 (11%), Positives = 66/225 (29%), Gaps = 26/225 (11%) Query: 433 REGDRV----------VTEVVTQIERMASAVVRSTEAMTALQEESDKIGSVMNVIRAVAE 482 +EG+ V + S+++++ T Q S I + + Sbjct: 113 KEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPD 172 Query: 483 QTNLLALNAAIEAARAGEAGRGFAVVADEVRGLAQRTQKSTEEIEGLVAALQNGTQQVAS 542 + ++ F+ ++ K E ++A + Sbjct: 173 EPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRV 232 Query: 543 I---MHTSRDLTDSG-------VELARRAGASLGSITRTVSNIQAMNQQIAAAAEEQSAV 592 + L +E + ++ + S ++ + +I +A EE V Sbjct: 233 EKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLV 292 Query: 593 AEEISRSVVNVRDVSEQTAAASEETAASSTELARLGGQLQMMVSR 637 + ++ ++ ++ + ELA+ + Q V R Sbjct: 293 TQLFKN------EILDKLRQTTDNIGLLTLELAKNEERQQASVIR 331
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 112 bits (280), Expect = 8e-33 Identities = 62/207 (29%), Positives = 103/207 (49%), Gaps = 5/207 (2%) Query: 1 MRRTKEEAEKTRIAILASAERLFLDKGVAHTSLDQIARDAGVTRGAVYWHFQNKAHLFHE 60 R+TK+EA++TR IL A RLF +GV+ TSL +IA+ AGVTRGA+YWHF++K+ LF E Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 61 MLNQIRLPPEQMTERLCSCDQQQPLQALIALRNLTVEAISTLASNEQKRRIFTILLHKCE 120 + + E + P L LR + + + + + E++R + I+ HKCE Sbjct: 62 IWELSE---SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCE 118 Query: 121 FTDELREAEERHHAFINQFIDLCENLLRNA--STCLRPGVTPRLAALSLHALVVGLFTDW 178 F E+ ++ + D E L++ + L + R AA+ + + GL +W Sbjct: 119 FVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENW 178 Query: 179 TRDTELFAPEVDTRALIDPLFRGLVRD 205 + F + + R + L + Sbjct: 179 LFAPQSFDLKKEARDYVAILLEMYLLC 205
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 81.5 bits (201), Expect = 6e-19 Identities = 58/265 (21%), Positives = 93/265 (35%), Gaps = 10/265 (3%) Query: 4 RILLILGALSAFGPLAIDMYLPAFPLLAQSFGTSVDHVQLSLAAYFIGLAIGQLVYGPLA 63 +IL+ L LS F L + + P +A F A+ + +IG VYG L+ Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 64 DRYGRRGPLLIGVTLFTLASLASAFAPSM-DWLIGVRFVQALGGCAGMVVARAVVRDLCD 122 D+ G + LL G+ + S+ S LI RF+Q G A + VV Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 123 PMTSAKVFSQLMLVMGLAPILAPVAGGALLASFGWPSIFILLTLFSAMCLVAVTLWLPE- 181 K F + ++ + + P GG + W + ++ + + L E Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEV 193 Query: 182 --TYPAGLPRQPMSGALGQYLRLFRDRFFIGHVLTGALCMAGMFAYI--TGSPFVFIELY 237 + + + LF + I ++ L +I PFV L Sbjct: 194 RIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLG 253 Query: 238 GVKPEHFGWLFG----INAAGFILM 258 P G L G AGF+ M Sbjct: 254 KNIPFMIGVLCGGIIFGTVAGFVSM 278
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 28.6 bits (63), Expect = 0.014 Identities = 17/36 (47%), Positives = 21/36 (58%), Gaps = 3/36 (8%) Query: 154 LRFDQI---DQALLQEAASMQHGGMHGHMPSDSHNA 186 LR DQ+ D +L EAA Q G GH+ S SH+A Sbjct: 103 LRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSA 138
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 33.5 bits (76), Expect = 1e-05 Identities = 13/58 (22%), Positives = 25/58 (43%) Query: 2 GISVWQLLIILLIVVMLFGTKRLRGLGSDLGGAISGFRKSVSDGETTAQAETVKQELK 59 I +LL++ +I +++ G +RL + G I R + + E QE + Sbjct: 3 DIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQ 60
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 101 bits (253), Expect = 4e-28 Identities = 70/256 (27%), Positives = 122/256 (47%), Gaps = 18/256 (7%) Query: 6 QDRLAVVTGASSGIGLALCSALLQRGARVLAMSRSIGGLEPLLET------HAEQLQWLR 59 + ++A +TGA+ GIG A+ L +GA + A+ + LE ++ + HAE Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF---P 63 Query: 60 GDVTSAEDLAQL-ARRAAQLGPVHYLVPNAGIAELA--DGLDMAAFDRQWAVNGAGALNT 116 DV + + ++ AR ++GP+ LV AG+ L ++ ++VN G N Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 117 FAALRNELA--KPASVVFVGTFLIRSTFPGLAAYIASKAALAAQARTLAVEFAPLDVRIN 174 ++ + + S+V VG+ +AAY +SKAA + L +E A ++R N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 175 MVSPGPTATAIWGSLGLSDDQLESVAEGVTKRLLPGHFL----ESAAVANVILFQLSQGA 230 +VSPG T T + SL ++ E V +G + G L + + +A+ +LF +S A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 231 RGVFGQDWVVDNGYTI 246 + + VD G T+ Sbjct: 244 GHITMHNLCVDGGATL 259
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 43.0 bits (101), Expect = 7e-08 Identities = 12/28 (42%), Positives = 21/28 (75%) Query: 14 RQRAFTLIELMVALAVLAILAAIAVPGY 41 +QR FTL+E+MV + ++ +LA++ VP Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNL 33
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.5 bits (66), Expect = 0.004 Identities = 9/22 (40%), Positives = 17/22 (77%) Query: 4 ATSRQTGVSLIEVLITLVILAV 25 AT +Q G +L+E+++ +VI+ V Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGV 24
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 56.8 bits (137), Expect = 2e-13 Identities = 23/61 (37%), Positives = 39/61 (63%) Query: 5 KARGFTLIEVMIVVVIIGILASIALPNYRQYVIRSNRTAAQAQMLDIANRQQHFLLANRA 64 K RGFTL+E+M+V+VIIG+LAS+ +PN ++++ A + ++ + N + L N Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHH 65 Query: 65 Y 65 Y Sbjct: 66 Y 66
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 135 bits (341), Expect = 5e-37 Identities = 90/411 (21%), Positives = 178/411 (43%), Gaps = 15/411 (3%) Query: 10 RTARVLPWLVAIAFFMQTLDGTILNTALPAMARDLAENPLRMQGVVIAYMLTVALLIPAS 69 R ++L WL ++FF L+ +LN +LP +A D + P V A+MLT ++ Sbjct: 11 RHNQILIWLCILSFF-SVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVY 69 Query: 70 GWIADRFGSRRIFVTAIVLFSVGSLLCALSTS-FNQLVASRVLQGLGGALMLPVGRLVVL 128 G ++D+ G +R+ + I++ GS++ + S F+ L+ +R +QG G A + +VV Sbjct: 70 GKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVA 129 Query: 129 RAFPRSEFVRIMAFIALPGLVGPLLGPTLGGWLVEYASWHWIFLINLPVGVIGCIAALRF 188 R P+ + I +G +GP +GG + Y HW +L+ +P+ I + L Sbjct: 130 RYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMK 187 Query: 189 MPDLKGPERVRFDTLGFVLFGAAMVLVTIALEGLGHMHMSHARVMLLLVVGAACMTAYWL 248 + + + FD G +L +V + + + + L+ V Sbjct: 188 LLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFV---------K 238 Query: 249 RAGRIDAPLFSPKLFRTRSFAVGIFGNLFARLGGGALPFLLPLLLQVALGYSPAQAGMS- 307 ++ P P L + F +G+ ++P +++ S A+ G Sbjct: 239 HIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI 298 Query: 308 MIPLALGAMAVKSMAKPIIDRLGYRRLLIGNTLLLGGLIASLATIDTQTPTWLLLVHLGL 367 + P + + + ++DR G +L L + + + T ++ ++ + + Sbjct: 299 IFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFV 358 Query: 368 IGMVNSMQFTAMNTVTLVGLSHADASSGNSLLSVVVQLSMSLGVATAGALL 418 +G ++ + T ++T+ L +A +G SLL+ LS G+A G LL Sbjct: 359 LGGLSFTK-TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 25.4 bits (55), Expect = 0.036 Identities = 12/51 (23%), Positives = 18/51 (35%) Query: 32 RQSQCRELAVLRELLDDLGQVIVRLEQDKAELTSGLRAEKAHVAQLRRQLD 82 + + L LE +KA+L + A+ LRR LD Sbjct: 269 LEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLD 319
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 82.8 bits (204), Expect = 4e-21 Identities = 48/194 (24%), Positives = 86/194 (44%), Gaps = 2/194 (1%) Query: 2 SNNISGKVVVITGASSGLGEVTARHLAALGARVVLAARRKDKLDALVAELTNAGGQAIAY 61 + I GK+ ITGA+ G+GE AR LA+ GA + +KL+ +V+ L A A+ Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 62 QTDVTSQEEVKTLIQGAVDTYGRIDVLINNAGLMAIAPLSDTRTDEWDRMIDINIKGLLY 121 DV + + G ID+L+N AG++ + +EW+ +N G+ Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 122 GVAAALPVFQKQNSGHFINIASVAGLKVFSPGGTVYSGTKFAVRAISEGLRHEVGGS-IR 180 + + SG + + S V Y+ +K A ++ L E+ IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPA-GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 181 TTTIEPGAVDSELK 194 + PG+ +++++ Sbjct: 182 CNIVSPGSTETDMQ 195
>SECA#SecA protein signature. Length = 901 Score = 52.2 bits (125), Expect = 3e-09 Identities = 19/34 (55%), Positives = 21/34 (61%) Query: 411 NALPFLGPNTDAPKQGRNEPCSCGSGKKYKKCCG 444 A L T K GRN+PC CGSGKKYK+C G Sbjct: 865 AAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHG 898
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 27.8 bits (62), Expect = 0.031 Identities = 11/50 (22%), Positives = 19/50 (38%) Query: 153 GAAALGLDATPMEGFDFKKLDEELGLRAQGLTSLVLVALGYRDETDFNAG 202 G + +GF L+E + LR +G +L+ G+ D Sbjct: 42 GIERIWSAIGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIY 91
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 32.1 bits (73), Expect = 0.003 Identities = 11/27 (40%), Positives = 14/27 (51%) Query: 151 VLVTGANGGVGSFAIALLARRGYQVIA 177 LVTGA G +G L G+QV+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVG 29
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.9 bits (168), Expect = 6e-17 Identities = 23/144 (15%), Positives = 48/144 (33%), Gaps = 1/144 (0%) Query: 1 MEVLSEQGFAATGIDSVLKRINVPKGSFYHYFNSKEAFGQAVLDRYASRFARKLDLLLLN 60 + + S+QG ++T + + K V +G+ Y +F K + + S Sbjct: 21 LRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAK 80 Query: 61 EADPPLQRIRNFVEDAKEGMAKYEFRRGCLVGNLGQEIMALPESFRLALEHTL-IDWQER 119 PL +R + E E RR + + + + L ++ +R Sbjct: 81 FPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDR 140 Query: 120 LACCLREAASQGQIDSDSDCDSLA 143 + L+ + +D A Sbjct: 141 IEQTLKHCIEAKMLPADLMTRRAA 164
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.8 bits (67), Expect = 0.001 Identities = 11/54 (20%), Positives = 23/54 (42%), Gaps = 1/54 (1%) Query: 40 YAWVKRYSKPQVQRQQVDDQQAELRRLRAELKRVTEE-RDILKKAAAYFAKESG 92 A++ +++ + D E+ +L A L++ EE R I + A + Sbjct: 18 KAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKA 71
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 30.7 bits (69), Expect = 0.004 Identities = 23/149 (15%), Positives = 39/149 (26%), Gaps = 12/149 (8%) Query: 86 AIAVAPTAPATSPSAPVEVIPAPEQPTAPEQAAGLQHEMSITLSPN-QGAEVKLEMKQGA 144 ++ VA AT S+P + + Q Q + S +P Q ++Q Sbjct: 10 SLFVATLTTATLVSSPAANALSSKAMDNHPQ----QTQSSKQQTPKIQKGGNLKPLEQRE 65 Query: 145 KVNYLWTANGGVVNYDTHGDPYNAPRDFYHGYGKGRSTAE-----DSGVLEAA--FDGKH 197 N + N DT Y G A +L D H Sbjct: 66 HANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATH 125 Query: 198 GWFWRNRTSKPVTVTLRTQGDYISIKRVI 226 G + + +++ Sbjct: 126 GDPHALKAFPSAINQDNYPNGGFTAEQIT 154
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 135 bits (341), Expect = 4e-37 Identities = 82/386 (21%), Positives = 151/386 (39%), Gaps = 80/386 (20%) Query: 5 IGIDLGTTNSCVSILENGKAKVIENAEGGRTTPSIIAYANDGE------ILVGQSAKRQA 58 + IDLGT N+ + + G+ V+ PS++A D VG AK+ Sbjct: 13 LSIDLGTANTLIYVK--GQGIVLNE-------PSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 59 VTNPHNTLYAVKRLIGRRFDEDVVQKDIQMVPYKIVKADNSDAWVEVNGQKMAPPQISAE 118 P N + A++ + +D V D + +KM Sbjct: 64 GRTPGN-IAAIRPM------KDGVIADFFVT------------------EKM-----LQH 93 Query: 119 ILKKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALA 178 +K++ + P ++ VP +R+A +++ + AG +I EP AAA+ Sbjct: 94 FIKQVHS---NSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIG 150 Query: 179 YGMDKAKGDHTVIVYDLGGGTFDVSVIEIAEVDGEHQFEVLATNGDTFLGGEDFDIRLID 238 G+ ++ +++V D+GGGT +V+VI + V + +GG+ FD +I+ Sbjct: 151 AGLPVSEATGSMVV-DIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEAIIN 200 Query: 239 YLVDEFKKESGMNLKGDPLAMQRLKEAAEKAKIELSSS----QQTDVNLPYITADATGPK 294 Y+ + G + AE+ K E+ S+ + ++ + P+ Sbjct: 201 YVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPR 247 Query: 295 HLNVKISRAKLEALVEDLVQRTIEPCRIALKDAGVD-VSKIDD--VILVGGQTRMPLVQQ 351 + S LEAL E L + +AL+ + S I + ++L GG + + + Sbjct: 248 GFTLN-SNEILEALQEPLTG-IVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDR 305 Query: 352 KVAEFFGKEARKDVNPDEAVAMGAAI 377 + E G +P VA G Sbjct: 306 LLMEETGIPVVVAEDPLTCVARGGGK 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.9 bits (75), Expect = 0.004 Identities = 22/82 (26%), Positives = 31/82 (37%), Gaps = 18/82 (21%) Query: 190 VLMVGPPGTGKTLLAKAI---AGEAKVPFFT-----ISGSDFVEMFVGV------GASRV 235 +++ G GTGK L+A+A+ PF I G GA Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR 222 Query: 236 RD-MFEQAKKHAPCIIFIDEID 256 FEQA+ +F+DEI Sbjct: 223 STGRFEQAEGGT---LFLDEIG 241
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 112 bits (282), Expect = 1e-35 Identities = 52/119 (43%), Positives = 73/119 (61%), Gaps = 13/119 (10%) Query: 4 TVVIVVHLLVALGVVALVLLQQGKGADAGASFGSGASATVFGSQGSATFLSRLTAILAGV 63 ++VV L+VA+G+V L++LQQGKGAD GASFG+GASAT+FGS GS F++R+TA+LA + Sbjct: 3 EALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLATL 62 Query: 64 FFVTSLGLAFFAKQQADQLSQ-AGLPDPAVLEVPVSKPAVEDVPVLEQRKPADTASDLP 121 FF+ SL L + ++ S+ L PA E + PA SD+P Sbjct: 63 FFIISLVLGNINSNKTNKGSEWENLSAPAKTEQT------------QPAAPAKPTSDIP 109
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 78.4 bits (193), Expect = 5e-17 Identities = 66/277 (23%), Positives = 96/277 (34%), Gaps = 76/277 (27%) Query: 340 VMGHVDHGKTSLLDYIRRAKVAVGEAG------------------GITQHIGAYHVETER 381 V+ HVD GKT+L + + A+ E G GIT G + E Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 382 GMVTFLDTPGHAAFTAMRARGAKATDIVILVVAADDGVMPQTQEAVQHAKAAGVPIVVAV 441 V +DTPGH F A R D IL+++A DGV QT+ + G+P + + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 442 NKIDKPDANPD----NIKNGLGALDVI-----------------PEEWG----------- 469 NKID+ + +IK L A VI E+W Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 470 ----GDTP-----------------FIPV---SAKMGTGVDELLEAVLLQAELLELKATP 505 G + PV SAK G+D L+E + + Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 506 SAPGRGVVVESRLDKGRGPVATVLVQDGTLRQGDMVL 542 + G V + + R +A + + G L D V Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVR 282
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 27.0 bits (59), Expect = 0.033 Identities = 19/105 (18%), Positives = 38/105 (36%), Gaps = 5/105 (4%) Query: 37 AQPPQGQQVETVNTVTAPAKPAAAPQPPVQDEAEADQSSIDRKV----KQQVAAQEAERK 92 P Q + + + + A + PV A A S V KQ+ E + Sbjct: 997 ITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 93 RYCETMRTNLAQLQNNPRVRVEDNGETRRLTEEERQSRINETRDK 137 ET N ++ + V+ N +T + + +++ +T + Sbjct: 1057 DATETTAQN-REVAKEAKSNVKANTQTNEVAQSGSETKETQTTET 1100
>SALVRPPROT#Salmonella virulence-associated 28kDa protein signature. Length = 241 Score = 29.3 bits (65), Expect = 0.017 Identities = 17/32 (53%), Positives = 18/32 (56%), Gaps = 1/32 (3%) Query: 8 SGECRESDVTPEA-AYLSRRQVLRGAMLSGAM 38 SG+C ESDV PE YLS R LR G M Sbjct: 194 SGQCPESDVHPENWKYLSYRNELRSGRDGGEM 225
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 380 bits (977), Expect = e-130 Identities = 139/365 (38%), Positives = 197/365 (53%), Gaps = 12/365 (3%) Query: 145 QTQLVATQNELAKARRARYTIAGFIGNSPAASEIKRQARRAAQLDATVLLRGETGTGKEL 204 L + +K +G S A EI R R Q D T+++ GE+GTGKEL Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKEL 175 Query: 205 LAQGIHNLSPRARGPFVAVNVAAIPESLVEAELFGTAPGAFTGADRKARIGKFEVANGGT 264 +A+ +H+ R GPFVA+N+AAIP L+E+ELFG GAFTGA + G+FE A GGT Sbjct: 176 VARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR-STGRFEQAEGGT 234 Query: 265 LFLDEIGDLPLPLQAKLLRVLQEQEVEPLGSNQVKALNVRVIAATHIDLEAKVAAGQFRD 324 LFLDEIGD+P+ Q +LLRVLQ+ E +G +VR++AAT+ DL+ + G FR+ Sbjct: 235 LFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFRE 294 Query: 325 DLYYRLNVLALRVPPLRERSSDIPAVVEHLLDDIANRSGQPPMELSPEALALLCAQPWRG 384 DLYYRLNV+ LR+PPLR+R+ DIP +V H + A + G EAL L+ A PW G Sbjct: 295 DLYYRLNVVPLRLPPLRDRAEDIPDLVRHFV-QQAEKEGLDVKRFDQEALELMKAHPWPG 353 Query: 385 NVRELGNLLERAQLSADGPQLQAAHL----------LPLLGEQARSADAPAYATSAPSAA 434 NVREL NL+ R + + P+ ARS + Sbjct: 354 NVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMR 413 Query: 435 LPTEATPSEELPLQPLAQTIAQAERRALQSALAACKGNRRRAAMELGISRASLYSKLQQH 494 + P + +A+ E + +AL A +GN+ +AA LG++R +L K+++ Sbjct: 414 QYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473 Query: 495 GLSQR 499 G+S Sbjct: 474 GVSVY 478
>SECA#SecA protein signature. Length = 901 Score = 29.5 bits (66), Expect = 0.042 Identities = 12/49 (24%), Positives = 24/49 (48%), Gaps = 3/49 (6%) Query: 165 IDQR-KQHLQQLDDLLKSVFLEMFG--DPVRNEKGWGKKQFSELLDDIE 210 +D K+HL +D L + + L + DP + K F+ +L+ ++ Sbjct: 771 LDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLK 819
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 77.6 bits (191), Expect = 1e-17 Identities = 52/248 (20%), Positives = 111/248 (44%), Gaps = 15/248 (6%) Query: 380 QMVDGVEQEVRVETFQEEKKIISLATIQSPLGSQFRITGLDGQGESSELALLLRAGGLAA 439 ++ D + EVR +F+E++ + + G G GQ +++ L A A Sbjct: 76 ELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAVDPAL 135 Query: 440 PMYFAEERTIGPSLGAENIKLGVQAAMWGFLFVAIFMVLIY------KFFGVLATIALLF 493 + E ++GP + E + V + L A +++ Y F + A +AL+ Sbjct: 136 KITSFE--SVGPKVSGELVWTAVWS-----LLAATVVIMFYIWVRFEWQFALGAVVALVH 188 Query: 494 NMVVLTAMMSMLNATLTLPGIAGIVLTMGMAVDANVLIFSRIREEI--ANGMSIQRAIHE 551 ++++ + ++L L +A ++ G +++ V++F R+RE + M ++ ++ Sbjct: 189 DVLLTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNL 248 Query: 552 GFDRAFSAIVDGNLTTLLVGGILFAMGTGPIKGFAVTLSIGILTSMFTAIIVTRGMVNLI 611 + S V +TTLL + G I+GF + G+ T ++++ V + +V I Sbjct: 249 SVNETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFI 308 Query: 612 YGGRDLKK 619 R+ +K Sbjct: 309 GLDRNKEK 316
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 297 bits (762), Expect = e-102 Identities = 104/305 (34%), Positives = 168/305 (55%), Gaps = 20/305 (6%) Query: 2 KRVINFMGVRHVAFALTVLLTVASLASLVVKGLNFGLDFTGGTLIELGYERPVELEQVRG 61 K +F + F +++ +AS+ +V GLNFG+DF GGT I +++ R Sbjct: 11 KTNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRA 70 Query: 62 QLVQAGFADAVVQSFG------ATTDVLVRMP------------GDDPQLGERVASALRN 103 L D ++ ++R+ +L +V +AL Sbjct: 71 ALEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTA 130 Query: 104 ADSGNSVSVKRVEFVGPAVGEELRDQGGLGMLLALGGILVYVAFRFQWKFGLGAVLSLFH 163 D ++ + E VGP V EL +L A I+ Y+ RF+W+F LGAV++L H Sbjct: 131 VDP--ALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVH 188 Query: 164 DVILVLGVFSFFQISFDLTVLAAVLAVIGYSLNDTIVIFDRIRENFRMLRKAELLENINI 223 DV+L +G+F+ Q+ FDLT +AA+L + GYS+NDT+V+FDR+REN + L + +N+ Sbjct: 189 DVLLTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNL 248 Query: 224 STTQTLLRTVATSVSTLLAVGALMVFGGENLWGFSLALLIGVGAGTYSSVYVAGMLLVWL 283 S +TL RTV T ++TLLA+ ++++GG+ + GF A++ GV GTYSSVYVA +++++ Sbjct: 249 SVNETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFI 308 Query: 284 KLTRD 288 L R+ Sbjct: 309 GLDRN 313
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 108 bits (271), Expect = 7e-28 Identities = 82/380 (21%), Positives = 138/380 (36%), Gaps = 66/380 (17%) Query: 22 VGIDLGTTNSLVAALRSGVTAPLADADGQVILPSVVRYHADH-------VEVGAQAKLAA 74 + IDLGT N+L+ G+ + PSVV D VG AK Sbjct: 13 LSIDLGTANTLIYVKGQGIV---------LNEPSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 75 ATDPFNTISSVKRLMGRGLADVKQMGEQLPYRFRQAESQMPFIETVQGAKSPVEVSAEIL 134 P N I++++ + +AD + L + FI+ V Sbjct: 64 GRTPGN-IAAIRPMKDGVIADFFVTEKMLQH----------FIKQVHSN----------- 101 Query: 135 RALRLRAEESLGGELVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAVAYG 194 S ++ VP +R+A +++A+ AG + L+ EP AAA+ G Sbjct: 102 ---------SFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAG 152 Query: 195 LDRQAEGVVAIYDLGGGTFDISILRLTKGVFEVLATGGDTALGGDDFDHTVADWILECAG 254 L + D+GGGT +++++ L V +GGD FD + +++ G Sbjct: 153 LPVSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYG 207 Query: 255 VSGDLEPGAQRELLKIA-----CDAKERLTDVDVVTVAYAGWSGEL--HRETFDALIEPM 307 L A E +K + R +V +A G E +AL EP Sbjct: 208 S---LIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEP- 263 Query: 308 IARSLKSCRRAVRDSGVELEEITA---VVMVGGSTRVPKVRSAVGQLFGREPLTDIDPDE 364 + + + A+ EL + +V+ GG + + + + G + DP Sbjct: 264 LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLT 323 Query: 365 VVAIGAAIQAETLAGNNRDG 384 VA G E + + D Sbjct: 324 CVARGGGKALEMIDMHGGDL 343
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 31.0 bits (70), Expect = 0.009 Identities = 14/84 (16%), Positives = 32/84 (38%), Gaps = 9/84 (10%) Query: 302 IIGNKLIDDTRVELRVDKGR-----PPLAKNPASERLAETAQRLYSEIDQRIEPI----A 352 + L + VE+ + + PL K + + ++ I + P+ Sbjct: 398 VTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVSPLPLGSG 457 Query: 353 MRFGTDAGYAYVPDSDKPAVLETM 376 M++ + Y+ S + AV+E + Sbjct: 458 MQYESSVSLGYLNQSFQNAVMEGI 481
>PF04183#IucA / IucC family Length = 580 Score = 29.1 bits (65), Expect = 0.008 Identities = 12/48 (25%), Positives = 21/48 (43%) Query: 18 REVAKAVLAATHEAATHAESKAENKYDTRGLEAAYLADGQRRRLHEIE 65 R VAK + +E HAES+ +++Y A + +R + Sbjct: 12 RLVAKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLW 59
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 100 bits (250), Expect = 1e-27 Identities = 74/254 (29%), Positives = 119/254 (46%), Gaps = 13/254 (5%) Query: 4 INGKVVLITGASSGIGEATARLLAAQGATVVLGARRLDRLEKLVAEIDESGGIAACRALD 63 I GK+ ITGA+ GIGEA AR LA+QGA + ++LEK+V+ + A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 64 VTSREDTQAFVDFAEQRFGRVDVIVNNAGVMPLSPLDALKVDEWNRMIDVNIRGVLHGIA 123 V E+ G +D++VN AGV+ + +L +EW VN GV + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 124 AGLPLMQRQRAGQFVNIASIGAYAVSPTAAVYCATKYAVRAISEGLRQEVGG-DIRVTLV 182 + M +R+G V + S A + A Y ++K A ++ L E+ +IR +V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 183 SPGVTESELAESI--SDDSARSAMDDFR---RIAIPAEAIARA--IAYAI-----DQPAD 230 SPG TE+++ S+ ++ A + + IP + +A+ IA A+ Q Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 231 VDVSELVVRPTASL 244 + + L V A+L Sbjct: 246 ITMHNLCVDGGATL 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.0 bits (200), Expect = 2e-18 Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 4/121 (3%) Query: 405 SAGTVLLVDDDEEVAALVGEMLEHLGYRVTHAASATDALGALQDGCQVDIVFSDVMMPGG 464 + T+L+ DDD + ++ + L GY V ++A + G D+V +DV+MP Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAG-DGDLVVTDVVMP-D 59 Query: 465 MNGVELAREIRTRALGVPVLLTSGYAEAAQQSAAAEG--VHVLAKPYRLEELATSLREAI 522 N +L I+ +PVL+ S A+E L KP+ L EL + A+ Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 523 E 523 Sbjct: 120 A 120
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 57.4 bits (138), Expect = 5e-12 Identities = 51/208 (24%), Positives = 89/208 (42%), Gaps = 27/208 (12%) Query: 8 EGFRALVIGASGGIGAALVDALRS---------------DPRCASVIALSRSSEP-ALDL 51 EG A + GA+ GIG A+ L S + +S+ A +R +E D+ Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 52 TDPASIEQAAASVAGQ-GPFHLIVNAAGVLHGADFMPEKRLADLNQAQLLATFQINTFGP 110 D A+I++ A + + GP ++VN AGVL + L+ + ATF +N+ G Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPG------LIHSLSDEEWEATFSVNSTGV 120 Query: 111 AMLLRHFSGLLDRQRGVFAMLSAKVGSIGDNRLGGWYSYRASKAALNMLIKTASIEVRRS 170 R S + +R ++++ G R +Y +SKAA M K +E+ Sbjct: 121 FNASRSVSKYMMDRRS-GSIVTVGSNPAGVPRTS-MAAYASSKAAAVMFTKCLGLELAEY 178 Query: 171 QPNAVLLALHPGTVNSRLSQPFRGEEIG 198 +++ PG+ + + +E G Sbjct: 179 NIRCNIVS--PGSTETDMQWSLWADENG 204
>PF06580#Sensor histidine kinase Length = 349 Score = 33.3 bits (76), Expect = 0.001 Identities = 20/137 (14%), Positives = 46/137 (33%), Gaps = 8/137 (5%) Query: 145 LLGAGFATSTYIASLSLISGPYALIGV-GTLIKVMPLLLSVAAFTLIYAAVPNTRVPLR- 202 +G G T T SL P + I +M L+L+ A + I + Sbjct: 17 GIGWGVYTLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQI 76 Query: 203 --HAIVGGVFTAVLFEAAKQLFGVYVSYFPSYQLIYGAFAAVPLFLLWVYLSWMIVLFGA 260 + V +++ A +++ + +PL L ++ ++ + Sbjct: 77 ILRVLPACVVIGMVWFVANTSIWRLLAFINTK----PVAFTLPLALSIIFNVVVVTFMWS 132 Query: 261 ELVCGLSSSQQWRRRPL 277 L G + +++ + Sbjct: 133 LLYFGWHFFKNYKQAEI 149
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 157 bits (398), Expect = 3e-52 Identities = 51/147 (34%), Positives = 74/147 (50%) Query: 8 AEQDRAAIAEGLSRLLADTYTLYLKTHNFHWNVTGPMFNTLHTMFETQYTELALAVDDIA 67 A+ ++ + L+ L++ + LY K H FHW V GP F TLH FE Y A VD IA Sbjct: 6 AKTNQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIA 65 Query: 68 ERIRTLGFPAPGTYAAYARLSSIKEEEGVPSAEEMIKLLVEGQEAVVRTARGIFPLLDKV 127 ER+ +G T Y +SI + SA EM++ LV + + ++ + L ++ Sbjct: 66 ERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLAEEN 125 Query: 128 NDEPTADLLTQRMQSHEKTAWMLRSLL 154 D TADL ++ EK WML S L Sbjct: 126 QDNATADLFVGLIEEVEKQVWMLSSYL 152
>SSPAMPROTEIN#Salmonella surface presentation of antigen gene type M signature. Length = 147 Score = 28.9 bits (64), Expect = 0.017 Identities = 16/49 (32%), Positives = 27/49 (55%) Query: 219 TPRIANRLLRRVRDFAEVRGRGEITRQIADLALNMLDVDERGFDHQDRR 267 T R NR L R +A +R + + RQI DL L ++ + E+ + + +R Sbjct: 55 TLRAENRQLSREEIYALLRKQSIVRRQIKDLELQIIQIQEKRSELEKKR 103
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 56.2 bits (135), Expect = 9e-11 Identities = 25/177 (14%), Positives = 51/177 (28%), Gaps = 3/177 (1%) Query: 56 SQSQATTQTNQKIAGEAKKTAAKQFESEQMEQRKVEQEKQAAAARAAEQKKAEEARKADA 115 + + E AE K E Sbjct: 995 TNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN 1054 Query: 116 AKAAAEKAAAAKKAEEAKKVEQQKQAEIAKKKAAEDLAKQKAAEEAKKKAAEEAKRKAAE 175 + A E A ++ + K + + + + K+ E K+ A E + KA Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 176 EAKKKAAAEAAKKKAAEDAKKKAAADAARKAAEDKKAQALAELLSDTTERQQALADT 232 E +K + K ++ + K+ ++ + AE + + + + ADT Sbjct: 1115 ETEKT---QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT 1168 Score = 55.1 bits (132), Expect = 2e-10 Identities = 24/148 (16%), Positives = 54/148 (36%), Gaps = 6/148 (4%) Query: 81 ESEQMEQRKVEQEKQAAAARAAEQKKAE-EARKADAAKAAAEKAAAAKKAEEAKKVEQQK 139 SE E ++++ EQ E A+ + AK A A + + + Sbjct: 1033 PSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT--NEVAQSGS 1090 Query: 140 QAEIAKKKAAEDLAKQKAAEEAKKKAAE--EAKRKAAEEAKKKAAAEAAKKKAAEDAKKK 197 + + + ++ A + E+AK + + E + ++ + K+ +E + AE A++ Sbjct: 1091 ETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETV-QPQAEPAREN 1149 Query: 198 AAADAARKAAEDKKAQALAELLSDTTER 225 ++ A E + T Sbjct: 1150 DPTVNIKEPQSQTNTTADTEQPAKETSS 1177 Score = 54.7 bits (131), Expect = 2e-10 Identities = 29/191 (15%), Positives = 62/191 (32%), Gaps = 1/191 (0%) Query: 34 FSMTPELPPSKPIVQATLYQLKSQSQATTQTNQKIAGEAKKTAAKQFESEQMEQRKVEQE 93 P PP+ T + S+ ++T +K +A +T A+ E + + V+ Sbjct: 1020 VDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKAN 1079 Query: 94 KQAAAARAAEQKKAEEARKADAAKAAAEKAAAAKKAEEAKKVEQQKQAEIAKKKAAEDLA 153 Q + + E A EK AK E + + ++++ K+ + Sbjct: 1080 TQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSE-T 1138 Query: 154 KQKAAEEAKKKAAEEAKRKAAEEAKKKAAAEAAKKKAAEDAKKKAAADAARKAAEDKKAQ 213 Q AE A++ ++ + A E K+ + + ++ Sbjct: 1139 VQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVEN 1198 Query: 214 ALAELLSDTTE 224 + T Sbjct: 1199 PENTTPATTQP 1209
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 116 bits (291), Expect = 5e-34 Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 14/113 (12%) Query: 67 YFEYDSSDLKPEAMRALDVHA---KDLKGNGARVVLEGHTDERGTREYNMALGERRSKAV 123 F ++ + LKPE ALD +L VV+ G+TD G+ YN L ERR+++V Sbjct: 222 LFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSV 281 Query: 124 QRYLVLQGVSPAQLELVSYGEERPVAMGN--DEQS--------WAQNRRVELR 166 YL+ +G+ ++ GE PV GN D A +RRVE+ Sbjct: 282 VDYLISKGIPADKISARGMGESNPVT-GNTCDNVKQRAALIDCLAPDRRVEIE 333
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.6 bits (69), Expect = 0.013 Identities = 23/107 (21%), Positives = 46/107 (42%), Gaps = 11/107 (10%) Query: 63 FMRPIGGVLLGIYADRKGRKAALQLIISLMTLSIAMIAFAPPFAAIGIAAPLLIVLARLM 122 M+ +LG +DR GR+ L + ++ + A++A AP ++ + R++ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW--------VLYIGRIV 105 Query: 123 QGFATGGEFASATSFLIESAPANRRGLYGSW--QMFGQGLAVFCGAG 167 G TG A A +++ + + R + + FG G+ G Sbjct: 106 AGI-TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG 151
>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature. Length = 393 Score = 32.3 bits (73), Expect = 0.002 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 2/33 (6%) Query: 275 VGLRLRYEISRQFAPYIGVTWSRAYGNTADMLR 307 L L Y ++ F PYIGV WSRA + AD +R Sbjct: 273 ASLALSYRLN-MFTPYIGVKWSRASFD-ADTIR 303
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 2e-22 Identities = 35/117 (29%), Positives = 64/117 (54%) Query: 2 KLLVAEDEPKTGIYLQQGLSEAGFTVDRVTSGTDALQHVLSAPYDLLILDVMMPGLDGWE 61 +LVA+D+ L Q LS AG+ V ++ + + + DL++ DV+MP + ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRLVRASGNEVPVLFLTARDRVEDRVKGLELGADDYLVKPFAFSELLARVRTLLRR 118 +L ++ + ++PVL ++A++ +K E GA DYL KPF +EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.3 bits (211), Expect = 2e-21 Identities = 39/134 (29%), Positives = 68/134 (50%) Query: 2 HVLLAEDDALIASGIVAGLNAQGLTVDHATTAANAEAMLRAANFDVLILDLGLPDEDGIS 61 +L+A+DDA I + + L+ G V + AA + A + D+++ D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LLRRLRQQGMALPVLVLTARDAVSDRVTGLQAGADDYLLKPFDLRELAARLHTLMRRMAG 121 LL R+++ LPVLV++A++ + + GA DYL KPFDL EL + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 RSVNIIEHGRLSYD 135 R + + + Sbjct: 125 RPSKLEDDSQDGMP 138
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 67.0 bits (163), Expect = 4e-13 Identities = 48/248 (19%), Positives = 83/248 (33%), Gaps = 15/248 (6%) Query: 816 PQVKLADDAVIQTSTEGVATIVEQAAVAEVTDERTAAEEPAVVEAAVEAPVQP-TEVAAG 874 P+V+ + V T+ I A+V + EE A V+ A P P T Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQ-----ADVPSVPSNNEEIARVDEAPVPPPAPATPSETT 1037 Query: 875 EVAPSEVPAVQ--TDVTPQPASEPVVEKTEAAPAAAPALTPSGRAPNDPREVRRRQREAE 932 E + Q A+E + E A A + N+ + +E + Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSN-VKANTQTNEVAQSGSETKETQ 1096 Query: 933 RL-AKEAA----EAEAKAAAAQPLASPEIVASEPAEETQTEAIAQPVASDAQPEQVVESA 987 KE A E +AK + P++ + ++ Q+E + + + V Sbjct: 1097 TTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK 1156 Query: 988 PAAEQLASEEPSVSPTVEPTQQAQTPVTE-PVAEVVEEKPEAPVSEEAPQTAPEEKAAEG 1046 Q + + P E + + PVTE E P + T P + Sbjct: 1157 EPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESS 1216 Query: 1047 DEPDNREK 1054 ++P NR + Sbjct: 1217 NKPKNRHR 1224 Score = 64.3 bits (156), Expect = 2e-12 Identities = 51/338 (15%), Positives = 101/338 (29%), Gaps = 43/338 (12%) Query: 496 YEMSQTEAEEA-QPVSSTR--TLVRQEAAVKTAPQRTAPAPAAAAAPAEAPAAAPAQEPS 552 Y++ E E+ Q V +T T +A V + P A EAP PA Sbjct: 978 YDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNE----EIARVDEAPVPPPAP--- 1030 Query: 553 LFKGLIKSLVGLFAGEAKEPQAAAEVEKKPASPRPQRNDERRSGRQQNRRRDSRGGRDEE 612 A ++ + AE K+ + + + QNR + + Sbjct: 1031 -------------ATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVK 1077 Query: 613 RKPREERQPREERQPREERQPRDDRQPREERQPRPPREERKPREQVEATEAQPRRERAPR 672 + + + +E Q E ++ +E K + + E T+ P+ Sbjct: 1078 ANTQTNEVAQSGSETKE-------TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVS 1130 Query: 673 EERKPREERKRELRAPIDEAPVTAAEEEQVERQPRA---------PREERKPRAEQQAVA 723 +++ E + + + P +E Q + A +P E V Sbjct: 1131 PKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVN 1190 Query: 724 AADELLQQTEDANEAEDAQDTNEASEGNDGERPRRRSRGQRRRSNRRERQRDANGNEIDE 783 + +++ E+ A N S +P+ R R R + N+ Sbjct: 1191 TGNSVVENPENTTPATTQPTVNSESS----NKPKNRHRRSVRSVPHNVEPATTSSNDRST 1246 Query: 784 VDESNAPVKTEEIAVAATAAALAANTTDTEAAPQVKLA 821 V + ++ A + A ++ Sbjct: 1247 VALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHIS 1284 Score = 61.2 bits (148), Expect = 2e-11 Identities = 46/312 (14%), Positives = 89/312 (28%), Gaps = 25/312 (8%) Query: 665 PRRERAPREERKPREERKRELRAPIDEAPVTAAEEEQVERQPRAPREERKPRAEQQAVAA 724 P E+ + ++A + P E +V+ P P P + VA Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 725 ADELLQQTEDANEAEDAQDTNEASEGNDGERPRRRSRGQ-----RRRSNRRERQRDANGN 779 + +T + NE + + T + E + ++ Q + S +E Q Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 780 EIDEVDESNAPVKTEEIAVAATAAALAANTTDTEAAPQVKLADDAVIQTSTEGVATIVEQ 839 E A V+TE+ + + +P+ + ++ T+ Q Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTS--------QVSPKQEQSE------------TVQPQ 1142 Query: 840 AAVAEVTDERTAAEEPAVVEAAVEAPVQPTEVAAGEVAPSEVPAVQTDVTPQPASEPVVE 899 A A D +EP QP + + V + + P Sbjct: 1143 AEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENT 1202 Query: 900 KTEAAPAAAPALTPSGRAPNDPREVRRRQREAERLAKEAAEAEAKAAAAQPLASPEIVAS 959 + + + R VR E + + A + V S Sbjct: 1203 TPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLS 1262 Query: 960 EPAEETQTEAIA 971 + + Q A+ Sbjct: 1263 DARAKAQFVALN 1274 Score = 50.4 bits (120), Expect = 4e-08 Identities = 54/293 (18%), Positives = 87/293 (29%), Gaps = 33/293 (11%) Query: 730 QQTEDANEAEDAQDTNEASEGNDGERPRRRSRGQRRRSNRRERQRDANGNEIDEVDESNA 789 ++ + + N + R + A E E+ A Sbjct: 986 EKRNQTVDTTNITTPNNIQADVPSVPSNNE---EIARVDEAPVPPPAPATP-SETTETVA 1041 Query: 790 PVKTEEIAVAATAAALAANTT--DTEAAPQVKLADDAVIQTSTEGVATIVEQAAVAEVTD 847 +E A TT + E A + K A QT+ V Q+ Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNE------VAQSGSETKET 1095 Query: 848 ERTAAEEPAVVEAAVEAPVQPTEVAAGEVAPSEVPAVQTDVTP-QPASEPVVEKTEAAPA 906 + T +E A VE +A V+ + EVP V + V+P Q SE V + E A Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQ-------EVPKVTSQVSPKQEQSETVQPQAEPARE 1148 Query: 907 AAPALTPSGRAPNDPREVRRRQREAERLAKEAAEAEAKAAAAQPLASPEIVASEPAEETQ 966 P + +P+ + E+ AKE + QP+ V + + Sbjct: 1149 NDPTV-----NIKEPQSQTNTTADTEQPAKET-----SSNVEQPVTESTTVNTGNSVVEN 1198 Query: 967 TEAIAQPVASDAQPEQVVESAPAAEQLASEEPSVSPTVEPTQQAQTPVTEPVA 1019 E + QP ES+ + P + VA Sbjct: 1199 PE---NTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248 Score = 48.5 bits (115), Expect = 2e-07 Identities = 55/354 (15%), Positives = 96/354 (27%), Gaps = 64/354 (18%) Query: 424 EALKDRTAEVRARVPFQVAAFLLNEKRNAITKIELRTRARIFILPDDHLETPHFEVQRLR 483 A T E A Q + + +++A + T EV + Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSG 1089 Query: 484 DDSPEILAGQASYEMSQTEAEEAQPVSSTRTLVRQEAAVKTAPQRTAPAPAAAAAPAEAP 543 ++ E + E + E EE V + +T QE T+ +P + P Sbjct: 1090 SETKET-QTTETKETATVEKEEKAKVETEKT---QEVPKVTSQV----SPKQEQSETVQP 1141 Query: 544 AAAPAQEPSLFKGLIKSLVGLFAGEAKEPQAAAEVEKKPASPRPQRNDERRSGRQQNRRR 603 A PA+E KEPQ ++ + +P + + Sbjct: 1142 QAEPARENDP------------TVNIKEPQ--SQTNTTADTEQPAKETSSNVEQPVTEST 1187 Query: 604 DSRGGRDEERKPREERQPREERQPREERQPRDDRQPREERQPRPPREERKPREQVEATEA 663 G P + E + + R + P E AT + Sbjct: 1188 TVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE-------PATTS 1240 Query: 664 QPRRERAPREERKPREERKRELRAPIDEAPVTAAEEEQVERQPRAPREERKPRAEQQAV- 722 R T A + A + + +A+ A+ Sbjct: 1241 SNDRS--------------------------TVALCDLTSTNTNAVLSDARAKAQFVALN 1274 Query: 723 --AAADELLQQTEDANEAEDAQDTNEASEGNDGERPRRRSRGQRRRSNRRERQR 774 A + + Q E NE + + S + S Q RR + + Q Sbjct: 1275 VGKAVSQHISQLEMNNEGQYNVWVSNTSMN------KNYSSSQYRRFSSKSTQT 1322
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 66.3 bits (162), Expect = 2e-16 Identities = 19/73 (26%), Positives = 29/73 (39%), Gaps = 3/73 (4%) Query: 9 AIALSYDG--VNAPSLSAKGDDELAEAILAIAREHEVPIYENADLVR-LLARLELGDEIP 65 AI + Y P ++ K D + + IA E VPI + L R L + IP Sbjct: 268 AIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEEGVPILQRIPLARALYWDALVDHYIP 327 Query: 66 EALYRTIAEIIAF 78 AE++ + Sbjct: 328 AEQIEATAEVLRW 340
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 115 bits (291), Expect = 9e-38 Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 1/89 (1%) Query: 2 TKSELIERIVTQQGLLSSKDVELAIKTMLEQMAQALATGDRIEIRGFGSFSLHYRAPRVG 61 K +LI ++ L + KD A+ + ++ LA G+++++ GFG+F + RA R G Sbjct: 3 NKQDLIAKVAEATEL-TKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 62 RNPKTGQSVSLDGKFVPHFKPGKELRDRV 90 RNP+TG+ + + VP FK GK L+D V Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 73.3 bits (180), Expect = 8e-17 Identities = 39/192 (20%), Positives = 75/192 (39%), Gaps = 30/192 (15%) Query: 6 TILVTGGTGSFGNTFVPMTLARYNPKKIIIFSRDEMKQ-WDMAKKFE-----GDKRVRFF 59 LVTG G G V L + + I D + +D++ K +F Sbjct: 2 KYLVTGAAGFIG-FHVSKRLLEAGHQVVGI---DNLNDYYDVSLKQARLELLAQPGFQFH 57 Query: 60 IGDVRDKDRLYRALD--GVDYVVHAAATKIVPTAEYNPFECVKTNVDGAMNLIDACIDKG 117 D+ D++ + + V + V + NP +N+ G +N+++ C Sbjct: 58 KIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK 117 Query: 118 VKGVVALST---------------DKASSPINLYGATKLASDKLFVAGNSYSGEHGTRFS 162 ++ ++ S+ D P++LY ATK A++ + ++YS +G + Sbjct: 118 IQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELM---AHTYSHLYGLPAT 174 Query: 163 VVRYGNVMGSRG 174 +R+ V G G Sbjct: 175 GLRFFTVYGPWG 186
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 107 bits (269), Expect = 1e-28 Identities = 72/348 (20%), Positives = 123/348 (35%), Gaps = 26/348 (7%) Query: 3 KALITGITGQDGSYLAELLLEKGYEVHGIKRRASLFNTQRVDHLYQDPHVNNRNFVLHYG 62 K L+TG G G ++++ LLE G++V GI ++ + + F H Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLE--LLAQPGFQFHKI 59 Query: 63 DLSDSSNLTRIIQEVQPDEVYNLGAQSHVAVSFESPEYTADVDAMGTLRLLEAIRLLGLE 122 DL+D +T + + V+ + V S E+P AD + G L +LE R ++ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 123 KKTRFYQASTSELYGLVQEIPQKETTPF-YPRSPYAVAKLYAYWITVNYREAYGMYACNG 181 AS+S +YGL +++P +P S YA K + Y YG+ A Sbjct: 120 ---HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 182 ILFNHESPRRGETFVTRKITRGLANIAQGLEQCLYMGNLDALRDWGHAKDYVRMQWMMLQ 241 F P K T+ + +G +Y RD+ + D + Sbjct: 177 RFFTVYGPWGRPDMALFKFTK---AMLEGKSIDVY-NYGKMKRDFTYIDDIAEAIIRLQD 232 Query: 242 QEQPEDFVIATGVQYSVREFIRWSAAELGITLKFEGQGVEELAIIEAIEGEKAPALKVGD 301 D + +G VE + I+A+E Sbjct: 233 VIPHADTQWTVETGTPAASIAPYRVYNIG-----NSSPVELMDYIQALEDA--------- 278 Query: 302 VVVRVDPRY--FRPAEVETLLGDPTKAKDKLGWVPEITVQEMCAEMVR 347 + + +P +V D + +G+ PE TV++ V Sbjct: 279 LGIEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVN 326
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 91.8 bits (228), Expect = 3e-23 Identities = 71/350 (20%), Positives = 129/350 (36%), Gaps = 65/350 (18%) Query: 8 TIFVAGHRGMVGSAIVRRLRALG------------YDNILTTGRDEL-----------NL 44 V G G +G + +RL G YD L R EL +L Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 45 LDQQAVHAWFQSHAINQVYLAAAKVGGIHANNTFPADFIYENLMIEANIIHAAHIHGVQK 104 D++ + F S +V+++ + + + P + NL NI+ + +Q Sbjct: 62 ADREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 105 LLFLGSSCIYPKHAEQPMREESLLTATLEPTNEP---YAIAKIAGIKLCESYNRQHVRDY 161 LL+ SS +Y + + P + + P YA K A + +Y+ H+ Sbjct: 121 LLYASSSSVYGLNRKMPFSTDD-------SVDHPVSLYAATKKANELMAHTYS--HLYG- 170 Query: 162 RSVMPT------NLYGPHDNFHPDNSHVIPALLRRFHEAVQRGDKEVVIWGSGKAMREFL 215 +P +YGP PD L +F +A+ G K + ++ GK R+F Sbjct: 171 ---LPATGLRFFTVYGPWGR--PD------MALFKFTKAMLEG-KSIDVYNYGKMKRDFT 218 Query: 216 HVDDMAAASVHVMEL----DQAAYQAATQPMLSH-----INVGTGVDCTIRTLAETIASV 266 ++DD+A A + + ++ D P S N+G + + + Sbjct: 219 YIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDA 278 Query: 267 TGFKGQLIFDSNKPDGAPRKLMDASRLKS-LGWEASITLEDGLRSAYGWY 315 G + + +P D L +G+ T++DG+++ WY Sbjct: 279 LGIEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 97.5 bits (243), Expect = 2e-25 Identities = 73/343 (21%), Positives = 121/343 (35%), Gaps = 56/343 (16%) Query: 1 MNVLLTGANGFLGRAIVAHLCRQ-------DRIT------LSCAVRSPLAQVRFATFAVG 47 M L+TGA GF+G + L D + L A LAQ F F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGF-QFHKI 59 Query: 48 DLCGANDWSQPLLGQQV--VIHAAARAHIMKDELADPLSEYRLVNVEGTLNLARQAAAAG 105 DL + V + R + + L +P + Y N+ G LN+ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAV-RYSLENPHA-YADSNLTGFLNILEGCRHNK 117 Query: 106 VERFIYISSIKVNGESTPLGKPFVSSD-APAPEDPYGLSKLEAEQGLMQLAAETGMEVVI 164 ++ +Y SS V G + + PF + D P Y +K E + G+ Sbjct: 118 IQHLLYASSSSVYGLNRKM--PFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATG 175 Query: 165 IRPPLVYGPGVKGNFA--SMIKLIDRGIPLP-FGAIHNKRSLVGVDNLVDLIIRCVDHPA 221 +R VYGP + + A K + G + + KR +D++ + IIR D Sbjct: 176 LRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIP 235 Query: 222 AANQ-----------------IFLAGDGKDLSTTELLLGVGKAMDKPAKLIPAPAGFLQL 264 A+ ++ G+ + + + + A+ AK P LQ Sbjct: 236 HADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLP---LQP 292 Query: 265 GATLLGKKAMAQRLLGSLQVDISKTCELLDWKPPYTVEEGLRR 307 G L + A D E++ + P TV++G++ Sbjct: 293 GDVL---ETSA---------DTKALYEVIGFTPETTVKDGVKN 323
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 66.7 bits (163), Expect = 5e-14 Identities = 52/293 (17%), Positives = 104/293 (35%), Gaps = 58/293 (19%) Query: 304 VMVTGAGGSIGSELCRQILSNKPQALLLFEHSEFN-LYSIHMELERLIERTSLPIRLVPI 362 +VTGA G IG + +++L Q + + N Y + ++ RL E + P Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGI---DNLNDYYDVSLKQARL-ELLAQP-GFQFH 57 Query: 363 LGSIRNADRLLDVMRTWGVETIYHAAAYKHVPMVEHNVAEGVLNNVIGTLNTAQAAVQAG 422 + + + + D+ + E ++ + V N +N+ G LN + Sbjct: 58 KIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK 117 Query: 423 VSNFVLIST---------------DKAVRPTNVMGSTKRVAELVLQALSREPAPGLFGTA 467 + + + S+ D P ++ +TK+ EL A Sbjct: 118 IQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANEL---------------MA 162 Query: 468 GSVHHVNKTRFTMVRFGNVLGSSGS---VIPRFYAQIRAGGPVTV-THPKITRYFMTIPE 523 + H+ T +RF V G G + +F + G + V + K+ R F I + Sbjct: 163 HTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDD 222 Query: 524 AAQLVIQA----------GSMGQGGD--------VFVLDMGQPVKIAELAEKL 558 A+ +I+ ++ G V+ + PV++ + + L Sbjct: 223 IAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQAL 275
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 106 bits (266), Expect = 3e-30 Identities = 80/241 (33%), Positives = 115/241 (47%), Gaps = 29/241 (12%) Query: 20 HWPLPEALTGARLLSTSFDPAQLDPEDFDRWGIP----VQKGVSKRQAEFLAGRLCALEA 75 H+PLP A G RL FD + D W +P ++ KR+AE LAGR+ A+ A Sbjct: 5 HFPLPFA--GHRLHIVDFDASSFREHDLL-W-LPHHDRLRSAGRKRKAEHLAGRIAAVHA 60 Query: 76 LRGLTGKPFVPPVGEDRAPQWPQGVVGSITHSAGWAGVVAGHREHWAGLGLDIERVMTSE 135 LR + G VP +G+ R P WP G+ GSI+H A A V + +G+DIE++M+ Sbjct: 61 LREV-GVRTVPGMGDKRQPLWPDGLFGSISHCATTALAVISRQR----IGIDIEKIMSQH 115 Query: 136 RADRLANEILTPSELEGYTLLSLGERAELVTR-SFSLKESLFKALYPLVKQRFYFQDAAV 194 A LA I+ E + L + L +FS KES++KA + F A V Sbjct: 116 TATELAPSIIDSDERQI--LQASLLPFPLALTLAFSAKESVYKA-FSDRVTLPGFNSAKV 172 Query: 195 AEVT-QHGTARLRLLIDLPGGWRTGAE--LDGQFATFDGYLLSLVS----IPAQHSLVAS 247 +T H + L LP T AE + ++ D +++LVS +P S AS Sbjct: 173 TSLTATHISLHL-----LPAFAATMAERTVRTEWFQRDNSVITLVSAITRVPHDRSAPAS 227 Query: 248 I 248 I Sbjct: 228 I 228
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 27.9 bits (62), Expect = 0.049 Identities = 10/32 (31%), Positives = 16/32 (50%), Gaps = 1/32 (3%) Query: 15 LKLAVNAAITLQRPLLVKGEPGTGKTMLAEQL 46 ++ T L++ GE GTGK ++A L Sbjct: 150 YRVLARLMQT-DLTLMITGESGTGKELVARAL 180
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 300 bits (771), Expect = e-100 Identities = 108/445 (24%), Positives = 201/445 (45%), Gaps = 8/445 (1%) Query: 9 RRKQDTEYMPEIQGAILEDSPWLARLTVWLTALLLAAVLIWANYAVLEEVTTGEGKAIPS 68 R K + E++P I RL + L I + +E V T GK S Sbjct: 34 REKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHS 93 Query: 69 SKIQTVQNLEGGIVAQIYVREGQVVNKGDTLLRLDNTRFLSNQEETEAERLSLLARVERL 128 + + ++ +E IV +I V+EG+ V KGD LL+L ++ +T++ L R Sbjct: 94 GRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRY 153 Query: 129 AAEAEGRPLALPEEIT---RDAPQLAEDE-----RALYESRQQRLRSEQRILKEQLTQKQ 180 + L E+ Q +E +L + + ++++ + L +K+ Sbjct: 154 QILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKR 213 Query: 181 QEVAEFRSKQQQYRSSLSLIQQELNMSTPLVETGAISQVEILRLRRSIVDVRGALDATTL 240 E ++ +Y + + + L+ + L+ AI++ +L V+ L Sbjct: 214 AERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKS 273 Query: 241 ALPRAEAAASEIQSRIEQSELAFRAEAFKDLNAARTLLQKITATSVAIDDRVSRTTVVSP 300 L + E+ + + F+ E L + +T ++R + + +P Sbjct: 274 QLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAP 333 Query: 301 VHGIIKQLRINTIGGVVQPGSDLLEIVPLEDSLLIEAKVRPQDIAFLHPGQKAMVKFSAY 360 V ++QL+++T GGVV L+ IVP +D+L + A V+ +DI F++ GQ A++K A+ Sbjct: 334 VSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF 393 Query: 361 DYTIYGGLKANLELISADTITDKDGRSFYLIQVRTEKNYLGSPGHQLVIIPGMVATVDII 420 YT YG L ++ I+ D I D+ + + + E+N L + + + GM T +I Sbjct: 394 PYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIK 453 Query: 421 TGEKSVLDYMLKPILKARHEALRER 445 TG +SV+ Y+L P+ ++ E+LRER Sbjct: 454 TGMRSVISYLLSPLEESVTESLRER 478
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 104 bits (261), Expect = 2e-24 Identities = 63/187 (33%), Positives = 84/187 (44%), Gaps = 39/187 (20%) Query: 1969 DSYSSIEGLMGGSGNDQLSGDSQANYLAGGAGDDILQGGAGDDVLVGGLGDDVLSGGEGD 2028 D+ S+E L+G + D+ G + G GDD+++G G+D L G G+D LSGG GD Sbjct: 714 DNLYSVEELIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGD 773 Query: 2029 DVLVGDPGSDQLLGGEGFDTVDYSADTAGVTVNLETGIGEGGLAEGDTYNSIEGILGGAG 2088 D L G G+D+L+G G + ++ GG G Sbjct: 774 DQLYGGDGNDKLIGVAGNNYLN----------------------------------GGDG 799 Query: 2089 NDTLTGDGG---DNYLDGGAGNDTLLGGAGDDILVGGVGDDTLTGGAGRDSFVWRVGDEG 2145 +D G N L GG GND L G G D+L GG GDD L GG G D + + G Sbjct: 800 DDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGY-- 857 Query: 2146 GTDTITD 2152 G I D Sbjct: 858 GHHIIDD 864 Score = 75.4 bits (185), Expect = 2e-15 Identities = 51/154 (33%), Positives = 67/154 (43%), Gaps = 28/154 (18%) Query: 1915 VLEGTAGDDVIAASNLTDIIDGKAGFDIVDYGDDTAGIAASLALAAGLSGTALGDSYSSI 1974 + G GDD+I ++ D + G G D + G+ GD Sbjct: 739 IFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGN--------------------GDDQ--- 775 Query: 1975 EGLMGGSGNDQLSGDSQANYLAGGAGDDILQ---GGAGDDVLVGGLGDDVLSGGEGDDVL 2031 L GG GND+L G + NYL GG GDD Q +VL GG G+D L G EG D+L Sbjct: 776 --LYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLL 833 Query: 2032 VGDPGSDQLLGGEGFDTVDYSADTAGVTVNLETG 2065 G G D L GG G D Y + ++ + G Sbjct: 834 DGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGG 867 Score = 70.0 bits (171), Expect = 1e-13 Identities = 59/222 (26%), Positives = 77/222 (34%), Gaps = 80/222 (36%) Query: 1918 GTAGDDVIAASNLTDIIDGKAGFDIVD--YGDDTAGIAASLALAAGLSGTALGDSYSSIE 1975 GT D S TDI G G D+++ G+D Sbjct: 724 GTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDR-------------------------- 757 Query: 1976 GLMGGSGNDQLSGDSQANYLAGGAGDDILQGGAGDDVLVGGLGDDVLSGGEGDDVLVGDP 2035 L G GND LSG + + L GG G+D L G AG++ L GG GDD Sbjct: 758 -LYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQGN-------- 808 Query: 2036 GSDQLLGGEGFDTVDYSADTAGVTVNLETGIGEGGLAEGDTYNSIEGILGGAGNDTLTGD 2095 + N+ + GG GND L G Sbjct: 809 ---------------------SLAKNV--------------------LFGGKGNDKLYGS 827 Query: 2096 GGDNYLDGGAGNDTLLGGAGDDILV--GGVGDDTLTGGAGRD 2135 G + LDGG G+D L GG G+DI G G + G++ Sbjct: 828 EGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKE 869 Score = 63.8 bits (155), Expect = 8e-12 Identities = 51/186 (27%), Positives = 69/186 (37%), Gaps = 38/186 (20%) Query: 1997 GGAGDDILQGGAGDDVLVGGLGDDVLSGGEGDDVLVGDPGSDQLLGGEGFDTVDYSADT- 2055 G GDD + AG + G G DV+ + D + G+ G T D Sbjct: 616 LGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVK 675 Query: 2056 -------------AGVTVNLE------TGIGEGGLAEGDTYNSIEGILGGA--------- 2087 T + T I L E D S+E ++G Sbjct: 676 VLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSK 735 Query: 2088 ---------GNDTLTGDGGDNYLDGGAGNDTLLGGAGDDILVGGVGDDTLTGGAGRDSFV 2138 G+D + G+ G++ L G GNDTL GG GDD L GG G+D L G AG + Sbjct: 736 FTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLN 795 Query: 2139 WRVGDE 2144 GD+ Sbjct: 796 GGDGDD 801 Score = 61.5 bits (149), Expect = 4e-11 Identities = 65/269 (24%), Positives = 89/269 (33%), Gaps = 50/269 (18%) Query: 2003 ILQGGAGDDVLVGGLGDDVLSGGEGDDVLVGDPGSDQLLGGEGFDTVDYSADTAGVTVNL 2062 G GDD + G + G+G DV+ D L +G T A VT L Sbjct: 613 ESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDG--TKATEAGNYTVTRVL 670 Query: 2063 ETG-------------------------------IGEGGLAEGDTYNSIEGILGGAGNDT 2091 I L E D S+E ++G D Sbjct: 671 GGDVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADK 730 Query: 2092 LTGD---------GGDNYLDGGAGNDTLLGGAGDDILVGGVGDDTLTGGAGRDSFVWRVG 2142 G GD+ ++G GND L G G+D L GG GDD L GG G D + G Sbjct: 731 FFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAG 790 Query: 2143 DE--GGTDTITDFQIDPAGTNTDVID----LSQLLVGVTEDAATLGDYLDFAFGGGSTTI 2196 + G D +FQ+ +V+ +L D G+ D GG I Sbjct: 791 NNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDI 850 Query: 2197 SVSLTPGGAPVQDITLSGIDLSTIYGTDV 2225 L+ G + I G + D+ Sbjct: 851 YRYLSGYGHHI--IDDDGGKEDKLSLADI 877
>PF06872#EspG protein Length = 398 Score = 29.3 bits (65), Expect = 0.024 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 11/91 (12%) Query: 227 FALANSQYTMGEKSAAEESLRVSVRLDPGFAIGWFNLSQLLAEQGCGSSAQ------EAR 280 L N +Y+ E+ + L V + P L ++ A+ GSS + E Sbjct: 60 LGLWNPKYSQDERQQFQGLLTVLEPVSPAHN----ELGRVYAKFSDGSSLRISVTNSELI 115 Query: 281 NCAIRLAPNDKRFRVALPAQEERRAAQCVPI 311 I PN+++F V L A E+ R Q +PI Sbjct: 116 EAEIH-TPNNEKFLVLLEANEQNRLLQSLPI 145
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 44.2 bits (104), Expect = 1e-07 Identities = 34/134 (25%), Positives = 52/134 (38%), Gaps = 14/134 (10%) Query: 23 ATLLVIDVQEEY-RSGVLALPALDRALPEITRLLAAAREAGAPIVHVHHLGISG----GL 77 A LL+ D+Q + + + I +L + G P+V+ G L Sbjct: 31 AVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDRAL 90 Query: 78 ---FDPQGFRG-----QIMPEAAPLPGEAVVAKRLPNAFSGTELHELLQKLGRLDLIVCG 129 F G +I+ E AP + V+ K +AF T L E+++K GR LI+ G Sbjct: 91 LTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITG 150 Query: 130 FMTHSSI-STTVRA 142 H T A Sbjct: 151 IYAHIGCLVTACEA 164
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 90.5 bits (224), Expect = 6e-24 Identities = 59/203 (29%), Positives = 99/203 (48%), Gaps = 5/203 (2%) Query: 11 LKGRIILVTGAGRGIGEAAAKAYAAHGATVLLLGKNEDNLNRVYDDIEAAGHPHPAIIPF 70 ++G+I +TGA +GIGEA A+ A+ GA + + N + L +V ++A H P Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEAR-HAEAFP- 63 Query: 71 NLETALPHQYDELAAMIEREFGHLDGLLHNAAIVGPRTPLEQLSGDNFMRVMQVNVNAMF 130 + DE+ A IERE G +D L++ A ++ P + LS + + VN +F Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVF 121 Query: 131 MLTSTLLPLLKLAKDASVIFTSSSVGRKGRAYWGAYAVSKFATEGLMQVLADEVDETAPV 190 + ++ + + S++ S+ R AYA SK A + L E+ E + Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN-I 180 Query: 191 RANSINPGATRTDMRAKAYPGEN 213 R N ++PG+T TDM+ + EN Sbjct: 181 RCNIVSPGSTETDMQWSLWADEN 203
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 42.4 bits (100), Expect = 3e-06 Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 3/41 (7%) Query: 342 DAHRALRMA---TLNGARALGIEDHTGSLEVGKFADLVAFD 379 D R R T+N A A G+ GSLEVGK ADLV ++ Sbjct: 398 DNFRVKRYIAKYTINPAIAHGLSHEIGSLEVGKRADLVLWN 438
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 54.2 bits (130), Expect = 2e-10 Identities = 58/317 (18%), Positives = 105/317 (33%), Gaps = 77/317 (24%) Query: 18 LHAATEVIQLNNRMAEDVIPVAESV----------------LGNQGRVTAYG--NQLIVN 59 T+VI L A D++ V + L + A+G N LIV Sbjct: 265 TQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNALIVT 324 Query: 60 APDSMISELRRVIDQLDVAPKRLLIS---VDTQDSASSSAG----------------GYQ 100 A ++++L RVI QLD+ ++L+ + QD+ + G G Sbjct: 325 AAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLP 384 Query: 101 VDGSVRSGDVEFETGR-------------GEIAG------RDRVRIIRRSTNSRDGGIQQ 141 + ++ + + G G AG + + ST + Sbjct: 385 ISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPS 444 Query: 142 VQASEGYPALIQVGQSVP-LTTQGTDGYGQIYQQTQYRDVLRGFYATATVHGD-----RV 195 + + A VGQ VP LT T I+ + + V ++ + Sbjct: 445 IVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEI 504 Query: 196 QISISSTRDRLAQGRSGVVEMQNA---DTRVSGRVGEWITIGGI--DESADSEQR----- 245 + +SS D + S + N + V GE + +GG+ +D+ + Sbjct: 505 EQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLG 564 Query: 246 -----GTLRRYSTQSSQ 257 G L R +++ Sbjct: 565 DIPVIGALFRSTSKKVS 581 Score = 35.3 bits (81), Expect = 2e-04 Identities = 17/72 (23%), Positives = 34/72 (47%), Gaps = 4/72 (5%) Query: 22 TEVIQLNNRMAEDVIPVAESVLGNQGRVTAYG----NQLIVNAPDSMISELRRVIDQLDV 77 T V+ L N A D+ P+ + N G + N L++ ++I L +++++D Sbjct: 129 TRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDN 188 Query: 78 APKRLLISVDTQ 89 A R +++V Sbjct: 189 AGDRSVVTVPLS 200
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 37.2 bits (86), Expect = 6e-06 Identities = 24/100 (24%), Positives = 41/100 (41%), Gaps = 8/100 (8%) Query: 41 DDADAIHFLALEGDYPIGTARLLAD----GQIGRVAVLRDWRGMNVGDALMRAVIAEAER 96 ++ FL + IG ++ ++ I +AV +D+R VG AL+ I A+ Sbjct: 61 EEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKE 120 Query: 97 RGLAEQKLTAQ---VHATAFYERLGFEVVS-DEFLEAGIP 132 L Q + A FY + F + + D L + P Sbjct: 121 NHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSNFP 160
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 154 bits (390), Expect = 3e-46 Identities = 86/357 (24%), Positives = 139/357 (38%), Gaps = 51/357 (14%) Query: 1 MKLKNTLGVVIGSMVAATSLSALAQGQGAVEVEAFGKHYFTDS-----SRDVQRDGELYG 55 MK K + + + AT A + G + D+ + + G Sbjct: 1 MK-KTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAG 59 Query: 56 AGVSYFLTDDVSLGLSYGEYHDLTSKDPVGVDGGHKN------IKGSLTSLDAAYHFGAP 109 A Y + V + Y + K V +G +K K D + Sbjct: 60 AFGGYQVNPYVGFEMGYDWLGRMPYKGSV-ENGAYKAQGVQLTAKLGYPITDDLDIYTRL 118 Query: 110 GVGLRPYVSAGVAHQSIGQADR--------GGRDSSTFANVGTGLKYYFTENFFAKASVD 161 G A G+ GG + + + T L+Y +T N ++ Sbjct: 119 GGM---VWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIG 175 Query: 162 GMYNIDADEAEWMAGVGVGLNFGGGARQVAAVEPTPEPAPAPIVDTEPEPAPELVRVELD 221 D M +GV FG G AA P PAPAP V T+ ++ D Sbjct: 176 --TRPDNG----MLSLGVSYRFGQGE---AAPVVAPAPAPAPEVQTKH------FTLKSD 220 Query: 222 VKFDFDKSRVREESYSDIKNLADFMQQY--PQTSTTVEGHTDSVGTDQYNQRLSERRAEA 279 V F+F+K+ ++ E + + L + S V G+TD +G+D YNQ LSERRA++ Sbjct: 221 VLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQS 280 Query: 280 VRNVLVNEYGVEGGRVNSVGYGESRPVADNSTEEGRQ---------INRRVEAEVEA 327 V + L+++ G+ ++++ G GES PV N+ + +Q +RRVE EV+ Sbjct: 281 VVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKG 336
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 309 bits (793), Expect = 6e-98 Identities = 108/446 (24%), Positives = 191/446 (42%), Gaps = 68/446 (15%) Query: 360 RAIGQRI-GAGPVKVIHDVSEMDKVQPGDVLVSDMTDPDWEPVMK-RASAIVTNRGGRTC 417 R + +R+ G ++ + + ++ D+T D + K T+ GGRT Sbjct: 132 RDVSKRVLGHLIGVETGSLATIA--EETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTS 189 Query: 418 HAAIIARELGIPAVVGCGNATELLKDGQRVTVSCAEG---------DTGLIFDGELGFDI 468 H+AI++R L IPAVVG TE ++ G V V EG + + F+ Sbjct: 190 HSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEK 249 Query: 469 RQNSIDAMPELP--------FKIMMNVGNPDRAFDFAHLPNEGVGLARLEFIINRMIGVH 520 ++ + P ++ N+G P EG+GL R EF+ Sbjct: 250 QKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLY------- 302 Query: 521 PKALLNFEGLPADVKSSVEKRIAGYDDPVNFYVEKLVEGVSTLAAAFWPKKVIVRLSDFK 580 ++ + LP + E++ Y + K V++R D Sbjct: 303 ----MDRDQLP-----TEEEQFEAY---------------KEVVQRMDGKPVVIRTLDIG 338 Query: 581 SNEYANLIGGKLYEPEEENPMLGFRGASRYISDSFRDCFELECRAMKKVRDVMGLTNVEL 640 ++ + L P+E NP LGFR + +D F + RA+ + N+++ Sbjct: 339 GDKELSY----LQLPKELNPFLGFRAIRLCLE--KQDIFRTQLRALLRAS---TYGNLKV 389 Query: 641 MVPFVRTLGEASQVIDLLAKYGLKRGENG------LRVIMMCELPSNALLADEFLEFFDG 694 M P + TL E Q ++ + K G + V +M E+PS A+ A+ F + D Sbjct: 390 MFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDF 449 Query: 695 FSIGSNDMTQLTLGLDRDSGIIAHLFDERNPAVKKLLANAIQACNKAGKYIGICGQGPSD 754 FSIG+ND+ Q T+ DR + +++L+ +PA+ +L+ I+A + GK++G+CG+ D Sbjct: 450 FSIGTNDLIQYTMAADRMNERVSYLYQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGD 509 Query: 755 HPDLAKWLMEQGIESVSLNPDSVLDT 780 L+ G++ S++ S+L Sbjct: 510 -EVAIPLLLGLGLDEFSMSATSILPA 534
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 29.5 bits (66), Expect = 0.034 Identities = 33/114 (28%), Positives = 45/114 (39%), Gaps = 21/114 (18%) Query: 434 FTDQYLLSLADALQRQHGIALIGGQS---------ITSPAPQNPARNDRARVVVCGAHLD 484 FT+Q S+ LQ GI GGQS +T+ P + R V V + D Sbjct: 66 FTEQ---SMRAMLQNL-GITTQGGQSNAKNIAAVMVTANLPPFASPGSRVDVTV-SSLGD 120 Query: 485 GLPLNWQLRQRGGRLLETTRSSPDYKLYALAGGPPLRPGMVRVAEGGAAVEVEV 538 L RGG L+ T+ S D ++YA+A G L A + V Sbjct: 121 ATSL------RGGNLIMTSLSGADGQIYAVAQG-ALIVNGFSAQGDAATLTQGV 167
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 88.6 bits (219), Expect = 5e-23 Identities = 71/259 (27%), Positives = 109/259 (42%), Gaps = 13/259 (5%) Query: 9 GRCVVITGAAGGIGRGLAQSFAAAGATLELLDRDADALARLADELAGDA-PLRCTALDLG 67 G+ ITGAA GIG +A++ A+ GA + +D + + L ++ L +A D+ Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 68 DRQAVQRYADDLACRGLHADVLVNNAGVEYATPLDECSFEADQCWSTLLENNVGSMQRLT 127 D A+ + D+LVN AGV + S E W N + + Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEE---WEATFSVNSTGVFNAS 124 Query: 128 RALLPRLRA--GASVINQASIWGLKGVP--GFSAYVASKHAVVGLTRSLAWELGPRRIRV 183 R++ + S++ S GVP +AY +SK A V T+ L EL IR Sbjct: 125 RSVSKYMMDRRSGSIVTVGS--NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 184 NAVCPGWIATDAAM-RSLQVMADANGRSDSAELATILSNQAIPELLTPADLGGTFLFLGS 242 N V PG +T+ M SL + + L T + + +L P+D+ LFL S Sbjct: 183 NIVSPG--STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 243 PLAAALTGQALSVSHGEVM 261 A +T L V G + Sbjct: 241 GQAGHITMHNLCVDGGATL 259
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 135 bits (340), Expect = 7e-41 Identities = 87/261 (33%), Positives = 128/261 (49%), Gaps = 11/261 (4%) Query: 1 MGSKRFAGQTALITGAATGIGRATALALAAEGARVWINHRDQHDLANQLVEQITANGGDA 60 M +K G+ A ITGAA GIG A A LA++GA + + L ++V + A A Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLE-KVVSSLKAEARHA 59 Query: 61 WAIEADVSDPAAVAAMFETIEAQ-GSLDLLVNNAGVILEKPFLETSEADWAMVLGVDLGG 119 A ADV D AA+ + IE + G +D+LVN AGV+ S+ +W V+ G Sbjct: 60 EAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTG 119 Query: 120 VYRCCRHALAQMQPRRSGAIVNVASDLGFLGREQYVAYCTAKAGVIGLTRSLAREFAADG 179 V+ R M RRSG+IV V S+ + R AY ++KA + T+ L E A Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 180 IRVNGVAPGPIATAMVSPEHMSDEWMAK---------ELAIPMARLGTPEEVAAAIVFLL 230 IR N V+PG T M + + + IP+ +L P ++A A++FL+ Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 231 SPQASYFTGQLLGPNGGSWMG 251 S QA + T L +GG+ +G Sbjct: 240 SGQAGHITMHNLCVDGGATLG 260
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 60.8 bits (147), Expect = 3e-13 Identities = 53/211 (25%), Positives = 83/211 (39%), Gaps = 23/211 (10%) Query: 7 LNPGRTALLVIDMQRDFCALGGYADQAGMDVSRLRAPIPAIQALLDRARSLGMLVVHTRE 66 +P R LL+ DMQ F + + A I+ L ++ LG+ VV+T Sbjct: 26 PDPNRAVLLIHDMQNYF--VDAFTAGASPVTEL----SANIRKLKNQCVQLGIPVVYT-- 77 Query: 67 GHRPDLSDLPEPKRRRAEATGAPIGSPGPLGRLLVRGEFGHDLIDELQPRAGEPVIDKPG 126 +P + + GP L G + +I EL P + V+ K Sbjct: 78 ---------AQPGSQNPDDRALLTDFWGPG---LNSGPYEEKIITELAPEDDDLVLTKWR 125 Query: 127 YSAFAYTDLELILRRRGIEQLILSGVTTEVCVSSTLRQAIDLGFDCVSISDACASSDPQL 186 YSAF T+L ++R+ G +QLI++G+ + T +A + DA A + Sbjct: 126 YSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEK 185 Query: 187 HAAALAMIEVEGGLFGSVTDSTELLRCLERA 217 H AL E G + LL L+ A Sbjct: 186 HQMAL---EYAAGRCAFTVMTDSLLDQLQNA 213
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.013 Identities = 16/55 (29%), Positives = 19/55 (34%), Gaps = 6/55 (10%) Query: 40 VTFVGASGCGKSTLLRIIAGLETLSRGEILLDGRPIDGPGVDRAMVFQHYSLYPW 94 V G G GKSTL+ + GL+ S D G G D Y Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFS------DTHFDIGTGKDSYEQIAGIVAYEL 647
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 103 bits (259), Expect = 7e-30 Identities = 60/203 (29%), Positives = 101/203 (49%), Gaps = 6/203 (2%) Query: 1 MRRTKEDAEQTRLKIIAAALELFSRNGYSNTTLAMIAEAAGFSRGPIYWHFKSKDELYEA 60 R+TK++A++TR I+ AL LFS+ G S+T+L IA+AAG +RG IYWHFK K +L+ Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 61 VLAYSQEPL-ERLIEQSRERAADPRAALEHFISEWFRLLLDERWYRQSFEILLNKTELTA 119 + S+ + E +E + DP + L + + E R EI+ +K E Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 120 QMASTLKRERKLTRAMVQLLEELIAKVHEDE-----RPARSLALLLYSSLMGITHTWLLS 174 +MA + +R L +E+ + E + R A+++ + G+ WL + Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181 Query: 175 PKLFSLREQAPCMALSLLALVKP 197 P+ F L+++A LL + Sbjct: 182 PQSFDLKKEARDYVAILLEMYLL 204
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.6 bits (199), Expect = 9e-18 Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 3/118 (2%) Query: 882 TLLAVDDDELVLFGTAGMLEAAGHRVLTARSAGEALDLLRTNQVDMLITDHAMPLMSGAQ 941 T+L DDD + L AG+ V +A + D+++TD MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 942 LAAVVRETRPQLPILLVSGYAELPSATPALPLR---RLAKPFSQNELLDAVEQLSARR 996 L +++ RP LP+L++S +A A L KPF EL+ + + A Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 54.6 bits (131), Expect = 5e-11 Identities = 37/195 (18%), Positives = 73/195 (37%), Gaps = 1/195 (0%) Query: 55 VMQTQLISLPPPVPVLPEPPVAEPVEAPPPPVQVEAPPQVEQADLAFKRAEREREAEQQR 114 Q+I LP P + VA PP VQ P VE E +EA Sbjct: 35 TSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVI 94 Query: 115 KQQLERRREEQRRRDEQQRREQERLAEQARLDAQRRQAEATARAEAAERARQAAAAEAAS 174 ++ + + + + + ++ +++ ++R + + A + + + Sbjct: 95 EKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVA 154 Query: 175 RQYLPIAKKPPVYPQRALDSGLQGACTVSYTVDVQGRVRSPKVV-GDCHPLFIRPSLIAA 233 +++ P YP RA ++G V + V GRV + +++ +F R A Sbjct: 155 SGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAM 214 Query: 234 QSFRYQPRIVDGRAV 248 + +RY+P V Sbjct: 215 RRWRYEPGKPGSGIV 229
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.017 Identities = 15/51 (29%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 54 GVLTEIVKNEGDTVLSGELLGKLEA-GAAAAAAPAQAAAPAAAAPAAAASA 103 ++ EI+ EG++V G++L KL A GA A Q++ A Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQI 155
>FLAGELLIN#Flagellin signature. Length = 507 Score = 152 bits (384), Expect = 1e-43 Identities = 110/374 (29%), Positives = 172/374 (45%), Gaps = 8/374 (2%) Query: 2 ALTVNTNIPSLNTQRNLNSSSNALATSMQRLSTGSRINSAKDDAAGLQIANRLTSQVNGL 61 A +NTN SL TQ NLN S ++L+++++RLS+G RINSAKDDAAG IANR TS + GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 GVAVRNANDGISLAQTAEGALQQSTNILQRMRDLALQSANGSNSTSEREALNSEVGQLKK 121 A RNANDGIS+AQT EGAL + N LQR+R+L++Q+ NG+NS S+ +++ E+ Q + Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 ELDRISNTTTFGGRQLLDGSFGVASFQVGSAANEIISVGIAEMSSKSLSAKFFENTSPKA 181 E+DR+SN T F G ++L + QVG+ E I++ + ++ KSL F PK Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQM-KIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 AVATTVTTAGEIDVG---FTVNGKAYAVTANVAVGDDEKTVNQKIAAAINDTNSGVGAFV 238 A + ++ + G + V Y V N + T + +G Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 239 KDDNTLSIVSRETEAGANSLSALSIAISTTAGKIPAGVTNPAAATLAATATSQKVSGVDL 298 +N ++ +T + G + T + + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKV 299 Query: 299 LSAENAQKAVL----VFDKAIQAIDAQRADLGAVQNRFDNTIANLQNISENVSAARGRIE 354 + N +K L + A A V N + ++N SA +E Sbjct: 300 STTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLE 359 Query: 355 DTDFAAETANLSKN 368 + + ++ N Sbjct: 360 ANNAVKGESKITVN 373 Score = 95.9 bits (238), Expect = 1e-23 Identities = 67/268 (25%), Positives = 110/268 (41%), Gaps = 2/268 (0%) Query: 127 SNTTTFGGRQLLDGSFGVASFQVGSAANEIISVGIAEMSSKSLSAKFFENTSPKAAVATT 186 N T + + G A + + A + G + + +T Sbjct: 242 ENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVST 301 Query: 187 VTTAGEIDVGFTVNGKAYAVTANVAVGDDEKTVNQKIAAAINDTNSGVGAFVKDDNTLSI 246 ++ + A + + + + K + + Sbjct: 302 TINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEAN 361 Query: 247 VSRETEAGANSLSALSIAISTTAGKIPAGVTNPAAATLAATATSQKVSGVDLLSAENAQK 306 + + E+ A A + AG T A+ S ++ + ++ Sbjct: 362 NAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDK--TASGVSTLINEDAAAAKKSTAN 419 Query: 307 AVLVFDKAIQAIDAQRADLGAVQNRFDNTIANLQNISENVSAARGRIEDTDFAAETANLS 366 + D A+ +DA R+ LGA+QNRFD+ I NL N N+++AR RIED D+A E +N+S Sbjct: 420 PLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMS 479 Query: 367 KNQILQQAGTAILAQAKQLPQAVLSLLQ 394 K QILQQAGT++LAQA Q+PQ VLSLL+ Sbjct: 480 KAQILQQAGTSVLAQANQVPQNVLSLLR 507
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 55.5 bits (133), Expect = 1e-09 Identities = 38/261 (14%), Positives = 85/261 (32%) Query: 652 RGQELERLLAERDEREAALAVVEERISELRAAQSRLEEEREQQRRRQQEEARIQGDLKAQ 711 + LE + A + +E + L A ++ LE+ E ++ L+A+ Sbjct: 125 LEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAE 184 Query: 712 LSAGQARLEQLGLRRQRLDEELAEQQDRREIETEQLGEARLQLQDALDAMAHDAEQRETL 771 +A +AR +L + + + + + D A+ Sbjct: 185 KAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTAD 244 Query: 772 LASRDGIRERLDRIRQDARQQKDHAHQLALRVGSLKAQHESTRQALERLEQQFERAIERR 831 A + + + + + A+ ++ LE + + Sbjct: 245 SAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQS 304 Query: 832 EQLTLNLEEGEAPLEELRMKLEELLERRMGVEEELKHARLALEDADRELRDAEKRRTQAE 891 + L N + L+ R ++L +EE+ K + + + R+L + + + Q E Sbjct: 305 QVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLE 364 Query: 892 QQAQLLRGQLEQQRLDWQGLS 912 + Q L Q + Q L Sbjct: 365 AEHQKLEEQNKISEASRQSLR 385 Score = 54.7 bits (131), Expect = 1e-09 Identities = 53/263 (20%), Positives = 99/263 (37%), Gaps = 9/263 (3%) Query: 634 QHFLRVRRASEAESGVLARGQELERLLAERDEREAALAVVEERISELRAAQSRLEEEREQ 693 + E+ A L + +I L A ++ LE + + Sbjct: 205 FSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAE 264 Query: 694 QRRRQQEEARIQGDLKAQLSAGQARLEQLGLRRQRLDEELAEQQDRREIETEQLGEARLQ 753 + + A++ +A L + L+ + R+ L +R Sbjct: 265 LEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREA 324 Query: 754 LQDALDAMAHDAEQRETLLASRDGIRERLDRIRQDARQQKDHAHQLALRVGSLKAQHEST 813 + EQ + ASR +R LD R +A++Q + HQ L+ Q++ + Sbjct: 325 KKQLEAEHQKLEEQNKISEASRQSLRRDLDASR-EAKKQLEAEHQ------KLEEQNKIS 377 Query: 814 RQALERLEQQFERAIERREQLTLNLEEGEAPLEELRMKLEELLERRMGVEEELKHARLAL 873 + + L + + + E ++Q+ LEE + L L +EL E + E+E + L Sbjct: 378 EASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKL 437 Query: 874 EDADRELRDAEKRRTQAEQQAQL 896 E + L+ EK QAE+ A+L Sbjct: 438 EAEAKALK--EKLAKQAEELAKL 458 Score = 49.7 bits (118), Expect = 6e-08 Identities = 54/366 (14%), Positives = 107/366 (29%), Gaps = 6/366 (1%) Query: 154 EAKPEDLRNFIEEAAGISKYKERRRETENRIRRTHENLARLTDLREELERQLERLHRQAQ 213 A + K++ + + N L D +EL +L + + Sbjct: 43 VATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLR 102 Query: 214 SAEKYQEYKAEERQLKAQLSALRWQALNELVGQREQVIGDQEVAFEALVAEQRSADASIE 273 +K E+ K Q R L + + + L AE+ + A Sbjct: 103 KNDK----SLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKA 158 Query: 274 RLRDGHHELSERFNQVQGRFYSVGGDIARVEQSIQHGQQRLRQLQDDLREAEQARLETES 333 L + ++ + A +E ++ L + E+ Sbjct: 159 DLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEA 218 Query: 334 HLGHDRTLLATLGEELAMLEPEQELSGAAAEESAVQLEEAEAAMQAWQEQWERFNQHSAE 393 A L + L A + + EA ++ E S Sbjct: 219 EKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTA 278 Query: 394 PRRAAEVQQSRIQQLEQSLERLAERQRRLDEERALLAADPEDV--AILELGEQLAASELD 451 + ++ LE L + + L+ R L D + A +L + E Sbjct: 279 DSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQ 338 Query: 452 LEALAAAAEDINERLEQLREELQQATRTQQQMQGELQRLNGRIASLEALQQAAMDPGKGV 511 + A+ + + L+ RE +Q Q+++ + + SL A+ + K V Sbjct: 339 NKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQV 398 Query: 512 AEWLRE 517 + L E Sbjct: 399 EKALEE 404 Score = 48.1 bits (114), Expect = 2e-07 Identities = 37/248 (14%), Positives = 92/248 (37%), Gaps = 7/248 (2%) Query: 655 ELERLLAERDEREAALAVVEERISELRAAQSRLEEEREQQRRRQQEEARIQGDLKAQLS- 713 EL + + + +L+ +I EL A ++ LE+ E ++ L+A+ + Sbjct: 93 ELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAA 152 Query: 714 ------AGQARLEQLGLRRQRLDEELAEQQDRREIETEQLGEARLQLQDALDAMAHDAEQ 767 + LE ++ + + + E L+ A++ D+ + Sbjct: 153 LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAK 212 Query: 768 RETLLASRDGIRERLDRIRQDARQQKDHAHQLALRVGSLKAQHESTRQALERLEQQFERA 827 +TL A + + R + + + + + ++ +L+A+ + LE+ E A Sbjct: 213 IKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA 272 Query: 828 IERREQLTLNLEEGEAPLEELRMKLEELLERRMGVEEELKHARLALEDADRELRDAEKRR 887 + + ++ EA L + +L + + + R L+ + + E Sbjct: 273 MNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEH 332 Query: 888 TQAEQQAQ 895 + E+Q + Sbjct: 333 QKLEEQNK 340 Score = 45.1 bits (106), Expect = 2e-06 Identities = 34/249 (13%), Positives = 80/249 (32%), Gaps = 8/249 (3%) Query: 659 LLAERDEREAALAVVEERISELRAAQSRLEEEREQQRRRQQEEARIQGDLKAQLSAGQAR 718 L + +I L A ++ LE + + + + A++ +A Sbjct: 160 LEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAE 219 Query: 719 LEQLGLRRQRLDEELAEQQDRREIETEQLGEARLQLQDALDAMAHDAEQRETLLASRDGI 778 L R+ L++ L + ++ ++ + A + E + Sbjct: 220 KAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTAD 279 Query: 779 RERLDRIRQDARQQKDHAHQLALRVGSLKAQHESTRQALERLEQQFERAIERREQLTLNL 838 ++ + + + L + RQ+L R A ++ E L Sbjct: 280 SAKIKTLEAEKAALEAEKADLE----HQSQVLNANRQSLRRDLDASREAKKQLEAEHQKL 335 Query: 839 EEG----EAPLEELRMKLEELLERRMGVEEELKHARLALEDADRELRDAEKRRTQAEQQA 894 EE EA + LR L+ E + +E E + + ++ + + + + Sbjct: 336 EEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAK 395 Query: 895 QLLRGQLEQ 903 + + LE+ Sbjct: 396 KQVEKALEE 404 Score = 44.3 bits (104), Expect = 3e-06 Identities = 52/343 (15%), Positives = 99/343 (28%), Gaps = 22/343 (6%) Query: 172 KYKERRRETENRIRRTHENLARLTDLREELERQLERLHRQA-QSAEKYQEYKAEERQLKA 230 R + + + E + L+ + L + E E K Sbjct: 40 VSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKE 99 Query: 231 QLSALR--WQALNELVGQREQVIGDQEVAFEALVAEQRSADASIERLRDGHHELSERFNQ 288 +L + + E D E A E + + A I+ L L+ R Sbjct: 100 KLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKAD 159 Query: 289 VQGRFYSVGGDIARVEQSIQHGQQRLRQLQDDLREAEQARLETESHLGHDRTLLATLGEE 348 ++ I+ + L+ E E+A + D + TL E Sbjct: 160 LEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAE 219 Query: 349 LAMLEPEQELSGAAAEESAVQLEEAEAAMQAWQEQWERFNQHSAEPRRAAEVQQSRIQQL 408 A L + A E + A ++ + + AE +A E + Sbjct: 220 KAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTAD 279 Query: 409 EQSLERLAERQRRLDEERALLAADPEDVAILELGEQLAASELDLEALAAAAEDINERLEQ 468 ++ L + L+ E A E + L A + + L+ Sbjct: 280 SAKIKTLEAEKAALEAE-------------------KADLEHQSQVLNANRQSLRRDLDA 320 Query: 469 LREELQQATRTQQQMQGELQRLNGRIASLEALQQAAMDPGKGV 511 RE +Q Q+++ + + SL A+ + K + Sbjct: 321 SREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQL 363 Score = 44.3 bits (104), Expect = 3e-06 Identities = 49/314 (15%), Positives = 104/314 (33%), Gaps = 9/314 (2%) Query: 170 ISKYKERRRETENRIRRTHENLARLTDLREELERQLERLHRQAQSAEKYQEYKAEERQLK 229 +S KE+ R+ + + + L + +LE+ LE + + + E+ Sbjct: 94 LSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 153 Query: 230 AQLSALRWQALNELVGQREQVIGDQ---EVAFEALVAEQRSADASIERLRDGHHELSERF 286 A A +AL + E AL A Q + ++E + S + Sbjct: 154 AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 213 Query: 287 NQVQGRFYSVGGDIARVEQSIQHGQQRLRQLQDDLREAEQARLETESHLGHDRTLLATLG 346 ++ ++ A +E++++ ++ E + E+ L Sbjct: 214 KTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAM 273 Query: 347 EELAMLEPEQELSGAAAEESAVQLEEAEAAMQAWQEQWERFNQHSAEPRRAAEVQQSRIQ 406 + + A + + E Q + + R A + ++ Q Sbjct: 274 NFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQ 333 Query: 407 QLEQSLE----RLAERQRRLDEERALLAADPEDVAILELGEQLAASELDLEALAAAAEDI 462 +LE+ + +R LD R + LE EQ SE ++L + Sbjct: 334 KLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLE--EQNKISEASRQSLRRDLDAS 391 Query: 463 NERLEQLREELQQA 476 E +Q+ + L++A Sbjct: 392 REAKKQVEKALEEA 405 Score = 43.9 bits (103), Expect = 3e-06 Identities = 40/237 (16%), Positives = 82/237 (34%), Gaps = 6/237 (2%) Query: 674 EERISELRAAQSRLEEEREQQRRRQQEEARIQGDLKAQLSAGQARLEQLGLRRQRLD--- 730 ++ EL S +E+ + + E+A +L+A+ + + LE Sbjct: 84 KDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKI 143 Query: 731 EELAEQQDRREIETEQLGEARLQLQDALDAMAHDAEQRETLLASRDGIRERLDRIRQDAR 790 + L ++ L +A + A + + E A+ + + L++ + A Sbjct: 144 KTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAM 203 Query: 791 QQKDHAHQLALRVGSLKAQHESTRQALERLEQQFERAIERREQLTLNLEEGEAPLEELRM 850 + + KA + + LE+ + LE +A LE + Sbjct: 204 NFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQA 263 Query: 851 KLEELLERRMGVEEELKHARLALEDADRELRDAEKRRTQAEQQAQLLRGQLEQQRLD 907 +LE+ LE G ++ + E E + E Q+Q+L + R D Sbjct: 264 ELEKALE---GAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRD 317
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 31.2 bits (70), Expect = 0.005 Identities = 15/38 (39%), Positives = 18/38 (47%), Gaps = 1/38 (2%) Query: 2 PVTRLPLRWAAITLAAIVLPAPAHAHGL-FDAHLLDRA 38 P+ RL AA +AA L PA A L D + D A Sbjct: 3 PLRRLTNLLAACAVAAAALIQPALAADLAQDPFITDNA 40
>PF01206#SirA family protein Length = 76 Score = 94.8 bits (236), Expect = 1e-29 Identities = 28/71 (39%), Positives = 44/71 (61%) Query: 10 DAVLDASGLNCPEPVMMLHNKVRDLAGGALLKVIATDPSTQRDIPKFCIFLGHDLVEQQE 69 D LDA+GLNCP P++ + + G +L V+ATDP + +D F GH+L+EQ+E Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 70 AAGTYLYWIRK 80 GTY + +++ Sbjct: 65 EDGTYHFRLKR 75
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 33.4 bits (76), Expect = 6e-04 Identities = 23/111 (20%), Positives = 46/111 (41%), Gaps = 6/111 (5%) Query: 194 GYYQLALKIEPRSLLAQNSLGYSYYLAGRWQDAERTFRRALDQNGSYTPLWRNYGLLLAR 253 G + +I +L SL ++ Y +G+++DA + F+ + + + G Sbjct: 23 GTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQA 82 Query: 254 TARYEEALSAFEQIGSRAQASNDV----GYVCLVE-GKLDEAEQFFRSALE 299 +Y+ A+ ++ G+ CL++ G+L EAE A E Sbjct: 83 MGQYDLAIHSY-SYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQE 132
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.3 bits (76), Expect = 0.002 Identities = 33/164 (20%), Positives = 57/164 (34%), Gaps = 5/164 (3%) Query: 20 LLISSRDAAALERLSTAIGSHPAWQVTTRLVNNGHTDPLFGLDHLPDLLLLHVSNLWRDE 79 +L++ DAA L+ A+ R+ +N T + DL++ V + Sbjct: 6 ILVADDDAAIRTVLNQALSR---AGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 80 LAAL-LLRPASQRPPLLVCGPLDEREGLRLAMQAGARDFLAEPVVAAELLAAIQRVAFES 138 L ++ A P+LV + A + GA D+L +P EL+ I R E Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 139 QAGVDAGGRLVA-VMNAKGGSGATMLACNLAHQLSGHGARTLLL 181 + M G S A + +L ++ Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT 166
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 30.1 bits (67), Expect = 0.012 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 5/69 (7%) Query: 82 DADLSEFSQGVKGHVRIHANTSAVIEFLPEDLSTFTRQHPEVKIDLEERVS--SDTLRAL 139 DA ++Q +KG I S +E + ++L F + E K + S +TL+AL Sbjct: 666 DARAIAYAQNLKG---IKRELSDKLENVNKNLKDFDKSFDEFKNGKNKDFSKAEETLKAL 722 Query: 140 REGLTDIGI 148 + + D+GI Sbjct: 723 KGSVKDLGI 731
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 5e-17 Identities = 34/119 (28%), Positives = 60/119 (50%), Gaps = 1/119 (0%) Query: 9 STVVVIDDITASLRLLESSVRAIGVQRIMAFSDSAAGLAWLQQNDWDLLLLDVDMPAPNG 68 +T++V DD A +L ++ G + S++A W+ D DL++ DV MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 69 FDILRSLSGREHNRMVVMVSALSDRESRCSSLKLGANDFISKPLDLPELLLRVRNQLQL 127 FD+L + + V+++SA + + + + GA D++ KP DL EL+ + L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.2 bits (172), Expect = 1e-14 Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 10/123 (8%) Query: 838 PRVFYVEDNPASQFLVRTALADIAL-VEVASNGVSALQQILAAPPDLVLLDLKLPEMNGE 896 + +D+ A + ++ AL+ V + SN + + I A DLV+ D+ +P+ N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 897 ELLSRLRRDVRCQGVPVVVLSA----VTGAEALRAASLDCQGLLRKPLDMQELRGLIEAL 952 +LL R+++ +PV+V+SA +T +A + D L KP D+ EL G+I Sbjct: 64 DLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYD---YLPKPFDLTELIGIIGRA 118 Query: 953 LAE 955 LAE Sbjct: 119 LAE 121
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.3 bits (154), Expect = 4e-14 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 5/112 (4%) Query: 23 RLLVVDDYPPGLMLLQQQFSFLGYRVVGASDGEAALAQWFAGDVDVVITDSRMPVMDGCA 82 +LV DD +L Q S GY V S+ AGD D+V+TD MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 83 LTEAIRQAERAKSAQPCLIIGFTANAVAEERERCLAAGMDECFFKPMDLVDI 134 L I+ +A+ P L++ +A + G + KP DL ++ Sbjct: 65 LLPRIK---KARPDLPVLVM--SAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.0 bits (161), Expect = 6e-15 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 1/113 (0%) Query: 3 TVLIVDDHPFICLAVRMLLERDGYSVVGEADNGVDAIQQAKVLQPDLVIVDIGIPKLDGL 62 T+L+ DD I + L R GY V N + DLV+ D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 SVIMRLRLLNDALKVLVLSSQPAGLFSTRCRQAGAAGYVCKSGDLGELSSAIQ 115 ++ R++ L VLV+S+Q + + + + GA Y+ K DL EL I Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 119 bits (301), Expect = 5e-32 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 1/128 (0%) Query: 6 ATLLIIDDDDVVRASLAAYLDDSGFRVLQAANGPQGMDLFDSEQPDLVICDLRMPQMDGL 65 AT+L+ DDD +R L L +G+ V +N + DLV+ D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 ELIRQISERQIDLPVIVVSGAGVMSDAVEALRLGAADYLIKPLEDLAMLEHSVRRALDRS 125 +L+ +I + + DLPV+V+S A++A GA DYL KP + ++ + RAL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG-IIGRALAEP 122 Query: 126 RLRLENRR 133 + R Sbjct: 123 KRRPSKLE 130
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.4 bits (188), Expect = 3e-18 Identities = 38/141 (26%), Positives = 64/141 (45%), Gaps = 3/141 (2%) Query: 7 RILIVEDDRRLAELTQEYLQGNGGFEVSIESDGACAVDRIIEERPDLVVLDLMLPGEDGL 66 IL+ +DD + + + L G++V I S+ A I DLVV D+++P E+ Sbjct: 5 TILVADDDAAIRTVLNQAL-SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 SICRRVRDRYDG-PILMLTARADDLDQVLGLETGADDYVCKP-VRPRLLLARIRALLRRQ 124 + R++ P+L+++A+ + + E GA DY+ KP L+ RAL + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 125 PPEASTNAKRLQFGPLVIDSA 145 + PLV SA Sbjct: 124 RRPSKLEDDSQDGMPLVGRSA 144
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.2 bits (135), Expect = 3e-12 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Query: 1 MGRKRTIDRDALLDVAEGIVNRQGAAALTIDAVAKAAGITKGGVQYSFGSKDDLINAMFE 60 ++ R +LDVA + ++QG ++ ++ +AKAAG+T+G + + F K DL + ++E Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 RWGKGYTEQFQRIAGDQP-DPLTAVRAHVEAT 91 E P DPL+ +R + Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHV 96
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 182 bits (464), Expect = 2e-54 Identities = 82/398 (20%), Positives = 164/398 (41%), Gaps = 14/398 (3%) Query: 18 LLIVIDMTVIYLALPSLTYELRASATEKLWIVNAYALTVAGLLPGMGALGDRFGHKRMFI 77 V++ V+ ++LP + + W+ A+ LT + G L D+ G KR+ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 78 SGLVVFGWASLGAAFSPTP-EILIAARVALAVGAAMMMPATLAIIRHVFEDTRERALAFG 136 G+++ + S+ + +LI AR GAA PA + ++ + R AFG Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAF-PALVMVVVARYIPKENRGKAFG 142 Query: 137 IWAAIASGGAAFGPVVGGVLLEHFWWGSVFIINVPIVLLALVLAVIWVPSRPGNPQRPFD 196 + +I + G GP +GG++ + W +++ +P++ + V ++ + + + FD Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKGHFD 200 Query: 197 LLASLWVMGALVGLTLAIKEAGKADPSLLQASVAACTAVVCALAFLRRQRQTAVPMIDFT 256 + + + +V L + + +V+ L F++ R+ P +D Sbjct: 201 IKGIILMSVGIVFFMLFTTSYSISFLIV---------SVLSFLIFVKHIRKVTDPFVDPG 251 Query: 257 LFRDRSFSAGVITASVASAALMGMELVVSQRLQLVVGLSPLQAG-LTILPIPLGAFIVGP 315 L ++ F GV+ + + G +V ++ V LS + G + I P + I G Sbjct: 252 LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGY 311 Query: 316 LAGLALPRIGAERILSTSLALSAAGALLYLLGYAGEQWLQILSFSLLGFGVGAAMTAASS 375 + G+ + R G +L+ + + L W + + G+ T S+ Sbjct: 312 IGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVIST 371 Query: 376 AMLLQAPADRAGMAASIEEVSYELGGALGIAILGSLMS 413 + AG S+ + L GIAI+G L+S Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>FLAGELLIN#Flagellin signature. Length = 507 Score = 66.2 bits (161), Expect = 7e-14 Identities = 60/352 (17%), Positives = 106/352 (30%), Gaps = 18/352 (5%) Query: 1 MRISTVQAFNNGVAGLQRNYANATRTQEQISTGNRILTPADDPVASVRLLQLEQQQNVLS 60 I+T L ++ ++ + E++S+G RI + DD + L+ Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLT 61 Query: 61 QYNSNLTAAKNSLTQEEVTLNSVNTVLQRVRELAVQAGNGGLSADDRKSIAAELTEREDE 120 Q + N + E LN +N LQRVREL+VQA NG S D KSI E+ +R +E Sbjct: 62 QASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEE 121 Query: 121 LLSLMNTRNARGEYLFSGFQGKTQPFVRDGAGSYSYQGDEGQRKLQIASSLNIAISDSGK 180 + + N G + S D ++G+ ++++ D Sbjct: 122 IDRVSNQTQFNGVKVLSQ----------DNQMKIQVGANDGETI-----TIDLQKIDVKS 166 Query: 181 SIFENVTNAGRYLSSLDITGQPGSTLRVSTPLVQDEVAIS---GNPPFPAAGVGVRFTSD 237 + G +++ + + Sbjct: 167 LGLDGFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDK 226 Query: 238 TEYVVYDLAAAPDFANPPIDPNLVLASGVVDQQEKTTEKLVFRGVVVQFDGIPVGGETVE 297 + D A +L + + + D G T Sbjct: 227 VYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFT 286 Query: 298 VQLDPAVQKQGILETISNLRKALEDPSSGNAGVRDAVAVALTNLDHGMISVD 349 + G + T N K + AG + A L + + SV Sbjct: 287 IDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVV 338 Score = 31.2 bits (70), Expect = 0.009 Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Query: 332 DAVAVALTNLDHGMISVDAARGNIGARLNVIETTQTDNEDVTLVN-KAVQAELRELDYAE 390 + A L ++D + VDA R ++GA N ++ N T+ N + ++ + + DYA Sbjct: 415 KSTANPLASIDSALSKVDAVRSSLGAIQNRFDSA-ITNLGNTVTNLNSARSRIEDADYAT 473 Query: 391 ALSRLSFQTIILEAAQQS 408 +S +S I+ +A Sbjct: 474 EVSNMSKAQILQQAGTSV 491
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 263 bits (674), Expect = 5e-82 Identities = 136/451 (30%), Positives = 237/451 (52%), Gaps = 21/451 (4%) Query: 2 ADLLSIGLSGLAASKTQLSITGHNITNVNTPGYSRQDATQATRSPQFSGAGYIGSGTTLV 61 + L++ +SGL A++ L+ +NI++ N GY+RQ A + G++G+G + Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 62 EVRRSYSEFLTSQLRSSTSLSADVEAYKSQINQLDSLLAGTTTGITPSLQKFFSALQTAA 121 V+R Y F+T+QLR++ + S+ + A Q++++D++L+ +T+ + +Q FF++LQT Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 122 EDPANIPARQLVLAEAEGLARRFNTVYDRLSEQNNFTNKQMSAVTDQVNRLAGSIGSLNE 181 + + ARQ ++ ++EGL +F T L +Q+ N + A DQ+N A I SLN+ Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 182 AIAIAAAN--GKQPNDLLDARDEAVRQLSGYIGVTVVPQDDSSFNIFIGSGQPLVVGSTV 239 I+ G PN+LLD RD+ V +L+ +GV V QD ++NI + +G LV GST Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 240 ARLEVVPGQGDPNRHEVQFISG--GSRQGITSQITGGELGGLIRYREEVLDSTMNSLGRL 297 +L VP DP+R V ++ G G+ + + G LGG++ +R + LD T N+LG+L Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 298 ALAVSDQVNTQLGQGLDLKGQVGSALFGDYNDPALAKLRVNAFAGNSSAQPVLN--ITNT 355 ALA ++ NTQ G D G G F A+ K V + + +T+ Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFF------AIGKPAV-LQNTKNKGDVAIGATVTDA 353 Query: 356 SQLSTSDYLMEYDGSSFKIRRLSDNQLMTATENPAGTLSITDKNGRDQGFQIVLGNPPPA 415 S + +DY + +D + +++ RL+ N T T + G ++ G ++ PA Sbjct: 354 SAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAF-------DGLELTFTG-TPA 405 Query: 416 PGDKFSLQPTRRGASDIKATLDQADQLAFAA 446 D F+L+P ++ + ++A A+ Sbjct: 406 VNDSFTLKPVSDAIVNMDVLITDEAKIAMAS 436 Score = 81.5 bits (201), Expect = 3e-18 Identities = 74/264 (28%), Positives = 112/264 (42%), Gaps = 34/264 (12%) Query: 431 DIKATLDQADQLAFAAPVRAQSTLQNSGTGV----------IGQPNLLSAPSPINAAALS 480 D+ T + QLA A A +T +G IG+P +L A+ Sbjct: 289 DLDQTRNTLGQLA-LAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIG 347 Query: 481 AAFEGLT--------LSYDGNGLTLPAPAPAGL-TLSPSSITAGQTNTLNLTLTTGTAPN 531 A + +S+D N + A T++P + + L LT T A N Sbjct: 348 ATVTDASAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVN 407 Query: 532 VQQYSFEFTVSG----RPETGDTFSF---NFNQSGVSDNRNALKLVDLQTKQTVGVTPGV 584 ++ + D + +G SDNRN L+DLQ+ Sbjct: 408 -DSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKT------ 460 Query: 585 AGSGFSFTDGYGELVERVGTLTAQARMDSEATGAILKQATDNRDSLSAVNLDEEAANLIK 644 G SF D Y LV +G TA + S G ++ Q ++ + S+S VNLDEE NL + Sbjct: 461 VGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQR 520 Query: 645 FEQYYNASAQIIQVARSLFDTLIS 668 F+QYY A+AQ++Q A ++FD LI+ Sbjct: 521 FQQYYLANAQVLQTANAIFDALIN 544
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 182 bits (462), Expect = 1e-56 Identities = 112/356 (31%), Positives = 180/356 (50%), Gaps = 74/356 (20%) Query: 19 DLNRLSQLKVGKDRDGEENVRKVAQEFESLFLNEMLKSMRAATEVLAKDNPLNSQASKQY 78 D L++LK D N+R VA++ E +F+ MLKSMR A L KD +S+ ++ Y Sbjct: 14 DAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDA---LPKDGLFSSEHTRLY 70 Query: 79 QDMYDQQLSVSLSKEGGGIGLADVLVRQLSKQTETVTRNNPFAQVAQTEGAAWPSKPAAG 138 MYDQQ++ ++ G G+GLA+++V+Q++ + + S PAA Sbjct: 71 TSMYDQQIAQQMTA-GKGLGLAEMMVKQMTPE----------------QPLPEESTPAAP 113 Query: 139 VESARDDSRLLNQRRLALPGKLSERQVANVSATAVPPAGDAVQPLVNVDWKPATAFVPPA 198 ++ + + Q +S VQ V Sbjct: 114 MKFPLE--------------TVVRYQNQALSQ--------LVQKAV-------------- 137 Query: 199 DKPLTINGVEKGAPNAPSKTRFSSSQEFIATMLPMAEKAAERLGIEPRFLVAQAALETGW 258 P + S+ F+A + A+ A+++ G+ ++AQAALE+GW Sbjct: 138 -------------PRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGW 184 Query: 259 GKSMIRQKDGSNSHNLFGIKATG-WKGASATVTTTEYVNGKATREKAGFRAYDSFEQSFD 317 G+ IR+++G S+NLFG+KA+G WKG +TTTEY NG+A + KA FR Y S+ ++ Sbjct: 185 GQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALS 244 Query: 318 DFVSLLENNDRYRTAIQVASNTGDSERFVKELQKAGYATDPQYARKISQIARKMQT 373 D+V LL N RY A+ A++ +E+ + LQ AGYATDP YARK++ + ++M++ Sbjct: 245 DYVGLLTRNPRY-AAVTTAAS---AEQGAQALQDAGYATDPHYARKLTNMIQQMKS 296
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 435 bits (1119), Expect = e-155 Identities = 164/365 (44%), Positives = 219/365 (60%), Gaps = 9/365 (2%) Query: 5 LLLLAGLLTLCAGAQAERLKDVATIHGVRSNQLIGYGLVVGLNGSGDQTTQTPFTVQTFN 64 L L T A A R+KD+A++ R NQLIGYGLVVGL G+GD +PFT Q+ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 65 NMLAQFGIKVPAGGNIQLKNVAAVSIHAELPPFAKPGQTIDITVSSIGNAKSLRGGSLLM 124 ML GI GG KN+AAV + A LPPFA PG +D+TVSS+G+A SLRGG+L+M Sbjct: 73 AMLQNLGITTQ-GGQSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIM 131 Query: 125 APLKGIDGNVYAIAQGNLVVGGFDAGGADGSRITVNSPSAGRIPGGATVERPVPSGFNQG 184 L G DG +YA+AQG L+V GF A G D + +T ++ R+P GA +ER +PS F Sbjct: 132 TSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFKDS 190 Query: 185 NTLTLNLNRPDFTTAKNIVDQINDL----LGPGVAQALDGGSISVTAPLDPSQRVDYLSI 240 L L L PDF+TA + D +N G +A+ D I+V P + ++ Sbjct: 191 VNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKP-RVADLTRLMAE 249 Query: 241 LENLEVEVGQAVAKVIINSRTGTIVIGQNVRVQPAAVTHGSLTVTITEEPQVSQPEPFSD 300 +ENL VE AKV+IN RTGTIVIG +VR+ AV++G+LTV +TE PQV QP PFS Sbjct: 250 IENLTVET-DTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFSR 308 Query: 301 GQTVVVPNSKVKAEQEAKPMFKFGPGTTLDEIVRAVNQVGAAPSDLMAILEALKQAGALQ 360 GQT V P + + A QE + G L +V +N +G ++AIL+ +K AGALQ Sbjct: 309 GQTAVQPQTDIMAMQEGSKVA-IVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQ 367 Query: 361 ADLIV 365 A+L++ Sbjct: 368 AELVL 372
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 167 bits (424), Expect = 4e-54 Identities = 85/222 (38%), Positives = 115/222 (51%), Gaps = 13/222 (5%) Query: 14 LALVGCVAPAPKPNDPYYAPVLPRTPLPAAQNNGAIYQAGFETN-----LYDDRKAHRVG 68 L+L GC P P P P NG+I+Q+ N L++DR+ +G Sbjct: 17 LSLTGCAWIPSTPLVQGATSAQP-VPGPTPVANGSIFQSAQPINYGYQPLFEDRRPRNIG 75 Query: 69 DIITITLNERTQASKNATSKLSKDSSANIGLGSLFGGAVSMANPLTGNSMNLGAEYEASR 128 D +TI L E ASK++++ S+D N G F L GN+ E Sbjct: 76 DTLTIVLQENVSASKSSSANASRDGKTNFG----FDTVPRYLQGLFGNA-RADVEASGGN 130 Query: 129 DTSGSGQAGQSNSLSGSITVTISEVLPNGILAVRGEKWMTLNTGDELVRIAGLVRADDIS 188 +G G A SN+ SG++TVT+ +VL NG L V GEK + +N G E +R +G+V IS Sbjct: 131 TFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTIS 190 Query: 189 TDNTVPSTRIADARITYSGTGAFADASQPGWLDRFF--MSPM 228 NTVPST++ADARI Y G G +A GWL RFF +SPM Sbjct: 191 GSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 12/51 (23%), Positives = 24/51 (47%) Query: 209 NGLGTVLQNTLENSNVSVVEELVNMITTQRAYEMNSKVISTADQMLSFVTQ 259 N + + S V++ EE N+ Q+ Y N++V+ TA+ + + Sbjct: 494 NVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 38.8 bits (90), Expect = 1e-05 Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 14/79 (17%) Query: 5 LWVSKTGLSAQDMNLTTISNNLANVSTTGFKRDRAEFQDLLYQIRRQPGGQSSQDSELPS 64 + + +GL+A L T SNN+++ + G+ R + +S L + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTLGA 49 Query: 65 GLQLGTGVRVTGTQKIFTA 83 G +G GV V+G Q+ + A Sbjct: 50 GGWVGNGVYVSGVQREYDA 68
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 40.3 bits (94), Expect = 1e-05 Identities = 17/49 (34%), Positives = 26/49 (53%) Query: 480 ALQAGALEDSNVELSDQLVNLIVAQRNYQANAKTIETESAITQTIINLR 528 L S V L ++ NL Q+ Y ANA+ ++T +AI +IN+R Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 39.9 bits (93), Expect = 2e-05 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Query: 2 SFNIGLSGLRAASKDLNVTGNNIANAGTVGFKQSRAEFSDVYAASVLGTGKNPQGSGVLM 61 N +SGL AA LN NNI++ G+ + + A S LG G G+GV + Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQ--ANSTLGAGGW-VGNGVYV 59 Query: 62 SNISQQ-----FNQGNINYTQNA 79 S + ++ NQ TQ++ Sbjct: 60 SGVQREYDAFITNQLRAAQTQSS 82
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 36.5 bits (84), Expect = 2e-05 Identities = 8/38 (21%), Positives = 20/38 (52%) Query: 108 NVNVVEEMADMISASRAFQTNAELMNTAKTMLQKVLTL 145 VN+ EE ++ + + NA+++ TA + ++ + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 31.1 bits (70), Expect = 0.001 Identities = 22/77 (28%), Positives = 29/77 (37%), Gaps = 15/77 (19%) Query: 4 SSVFNIAGSGMSAQSTRLNTISSNIANAETVSSSVDQTYRARHPVFATVFQQANGQPDQS 63 SS+ N A SG++A LNT S+NI++ + T A S Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMA---------------QANS 45 Query: 64 LFAGQDQAGVGVQVLGV 80 G GV V GV Sbjct: 46 TLGAGGWVGNGVYVSGV 62
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.2 bits (133), Expect = 1e-10 Identities = 21/126 (16%), Positives = 50/126 (39%), Gaps = 18/126 (14%) Query: 180 RVLIVDDSSVARKQITRCLENIGIEVVKLNDGREALNYLKRMADEGKKPAEEFLMMISDI 239 +L+ DD + R + + L G +V ++ ++ A + ++++D+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA---------AGDGDLVVTDV 55 Query: 240 EMPEMDGYTLTTEVR-HDPRMQGMHILLHTSLSGVFNQNMVK--RAGADDFLAK-FQPDD 295 MP+ + + L ++ P + + + + +K GA D+L K F + Sbjct: 56 VMPDENAFDLLPRIKKARPDLPVLVMSAQNTFM-----TAIKASEKGAYDYLPKPFDLTE 110 Query: 296 LAARVA 301 L + Sbjct: 111 LIGIIG 116
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 28.4 bits (63), Expect = 0.027 Identities = 9/23 (39%), Positives = 14/23 (60%) Query: 212 EQVAARPGWQAIPAVRTGQLHEI 234 + + A P WQA+P VR G+ + Sbjct: 247 DALMATPLWQAMPFVRAGRFQRV 269
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 61.0 bits (148), Expect = 2e-12 Identities = 72/359 (20%), Positives = 121/359 (33%), Gaps = 62/359 (17%) Query: 40 LPMLAAHFSVSAASSSLALSLTTLSLALCLLISGALAESWGRKPVMAAAL---GLASLLG 96 LP +A F+ AS++ + L+ ++ + G L++ G K ++ + S++G Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 97 LASVLVDSWQLLLALRALLGLALSGLPALAMAYVGEEFEPQSLPAAMGLYIGGTALGGML 156 S L+ R + G + PAL M V ++ A GL A+G + Sbjct: 97 FVGHSFFSL--LIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGV 154 Query: 157 GRLLSGLLSDLGGWQLALGGIASLGLLALALFVWLLPASRH------------------- 197 G + G+++ W L + L L R Sbjct: 155 GPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFF 214 Query: 198 ---------------------FKAQPLSLRNLLANFRLHLRNPTLRSLFLQG--FLLMGG 234 F + + + L P + + G F + G Sbjct: 215 MLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAG 274 Query: 235 FVALFNYIGFRLAGEPFGLSSTLIG--LLFVVYLGGIFSAGWAGRLVPRFGARQVLRGGV 292 FV++ Y + + LS+ IG ++F + I G LV R G VL GV Sbjct: 275 FVSMVPY----MMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGV 330 Query: 293 VLMLLGVGLCA-----TPWLAAIVLGLGLFTLGFFAAHA-VASGQVGSHAKQARAQASA 345 + + + T W I++ +F LG + V S V S KQ A A Sbjct: 331 TFLSVSFLTASFLLETTSWFMTIII---VFVLGGLSFTKTVISTIVSSSLKQQEAGAGM 386
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 32.8 bits (74), Expect = 1e-04 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 44 SACPAAESFSLTTA-GGRTFQLSYEPLCRAASDLSGLFVAVATVLAALYVGRAV 96 + CPA +F++T R F S+E C A L + +A+A +AA + R V Sbjct: 444 AQCPAPVTFTVTVLDSSRQFAFSFENACTIAERLRYMLLALAWAVAAFFCIRTV 497
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 24.7 bits (53), Expect = 0.022 Identities = 14/44 (31%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Query: 10 DCCGNDMGKLMALPAPQSDLLPDLSLPPHFAVCPDCEPSEQPAD 53 D GN + +P P DL P + P+ P+ P+E PA+ Sbjct: 298 DSQGNTTVDVQVIPRP--DLTPGSAEAPNAQPLPEVSPAENPAN 339
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 29.2 bits (65), Expect = 0.013 Identities = 23/139 (16%), Positives = 46/139 (33%), Gaps = 9/139 (6%) Query: 20 PWRFLAILGIGSVLLSGLAFTFGKPVVLDVNQIKQGIHIGGNPWFNQEPEQPIQLASQPS 79 PW L + I +++GL +T V+ ++ Q I + +P + Sbjct: 10 PWPTLLSVCIHGAVVAGLLYTSVHQVI-ELPAPAQPISV---TMVTPADLEP-----PQA 60 Query: 80 IASYEAPEAEPTPAPQQRPLTQEEIEWFEEGTARALQQRQTSFNDSNYTPRPFANTIQPP 139 + P EP P P+ P +E E + + P+ ++ Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 Query: 140 PARYYAANSTSSTQKRSVT 158 PA + + + + T Sbjct: 121 PASPFENTAPARLTSSTAT 139
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 28.4 bits (63), Expect = 0.012 Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 4/47 (8%) Query: 20 AVTAREAVAEARVRMLPQTLQMIQQGGHPKGDVFAVARIAGIQAAKK 66 TA+EAVA A VR+L + Q+ Q D+ + R AGI+ A + Sbjct: 353 QATAQEAVAAAAVRLLNGSDQIAQL----YKDLVKLQRHAGIRKAME 395
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.8 bits (69), Expect = 0.017 Identities = 22/124 (17%), Positives = 40/124 (32%), Gaps = 9/124 (7%) Query: 128 EQQIRSQLVRAEALEATNKPLAAARERVFTAPLLSGEQARANHESIWKLVSALPEKQLQS 187 E + R+Q V + N A + P + E AR + + A P + ++ Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVP----SVPSNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 188 AAEADLAGWQALALSLKRAGTVAQQQR-----AMDDWIAQNPQHPAAQQLPEPLQKLREL 242 AE + + + + A Q R A + A + AQ E + Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 243 ADQP 246 + Sbjct: 1100 TKET 1103
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 29.1 bits (65), Expect = 0.017 Identities = 20/87 (22%), Positives = 34/87 (39%), Gaps = 15/87 (17%) Query: 112 AALDESLRRLQTDWIDLY----QLHWPERSTNFFGQLGYRHQEDDFTPIEETLEALDDEV 167 ++ SL ++W LY + HW + +FF H++ F + + D + Sbjct: 11 TLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTL----HEK--FEELYDHAAETVDTI 64 Query: 168 RAGRIRHIGLSNETPWGLTK-YLQLAE 193 A R+ IG P K Y + A Sbjct: 65 -AERLLAIGGQ---PVATVKEYTEHAS 87
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 339 bits (871), Expect = e-120 Identities = 163/284 (57%), Positives = 200/284 (70%), Gaps = 1/284 (0%) Query: 2 ILLDYLASHVLAFVLSAAVLGLLVGSFLNVVIYRLPIMMQRDWRMQALEYLESPAEPVGE 61 +LL+ + + L++GSFLNVVI+RLPIM++R+W+ + Y E V E Sbjct: 3 LLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDE 62 Query: 62 -RFNLLLPNSRCPHCNHQIRSWENIPLVSWLALRGKCSSCRAPISCRYPLVELACGLLSG 120 +NL++P S CPHCNH I + ENIPL+SWL LRG+C C+APIS RYPLVEL LLS Sbjct: 63 PPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSV 122 Query: 121 YVAWHFGFSWQAGAMLLLTWGLLAMSMIDVDHQLLPDVLVLPLLWLGLILNNFGLFVSLE 180 VA W A LLLTW L+A++ ID+D LLPD L LPLLW GL+ N G FVSL Sbjct: 123 AVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLG 182 Query: 181 SALWGAVAGYLSLWSVYWLFKVVTGKEGMGYGDFKLLAMLGAWGGWQVLPLTILLSSVVG 240 A+ GA+AGYL LWS+YW FK++TGKEGMGYGDFKLLA LGAW GWQ LP+ +LLSS+VG Sbjct: 183 DAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVG 242 Query: 241 AVLGSILLRMQRAESNTPIPFGPYLAIAGWIALLWGDWITESYL 284 A +G L+ ++ + PIPFGPYLAIAGWIALLWGD IT YL Sbjct: 243 AFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYL 286
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 436 bits (1124), Expect = e-154 Identities = 122/404 (30%), Positives = 216/404 (53%), Gaps = 10/404 (2%) Query: 11 FTWEGTNRQGAKIKGELSGVSPALVKAQLRKQGVNPQKVR--------KKSVSL-FGAGK 61 + ++ + QG K +G S + LR++G+ P V S L Sbjct: 4 YHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRKI 63 Query: 62 KIKPMDIALFTRQMATMMKAGVPLLQSFDIIGEGFDNPNMRKLVDDLKQEVAAGNSFATA 121 ++ D+AL TRQ+AT++ A +PL ++ D + + + P++ +L+ ++ +V G+S A A Sbjct: 64 RLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADA 123 Query: 122 LRKKPQYFDDLYCNLVDSGEQSGSLETLLDRVATYKEKTEALKAKIKKAMNYPIAVVLVA 181 ++ P F+ LYC +V +GE SG L+ +L+R+A Y E+ + ++++I++AM YP + +VA Sbjct: 124 MKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVA 183 Query: 182 IIVSAILLIKVVPQFQDVFANFGAELPAFTLMVIGLSEALQAWWHVVLFVMFGVAYAFKT 241 I V +ILL VVP+ + F + LP T +++G+S+A++ + +L + AF+ Sbjct: 184 IAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR- 242 Query: 242 AHGKSERFRNGFDRFLLRIPVVGDILYKSAVARFARTLATTFAAGVPLVDALDSVAGATG 301 + E+ R F R LL +P++G I AR+ARTL+ A+ VPL+ A+ Sbjct: 243 VMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMS 302 Query: 302 NVVFRNATMKVKSDVSSGMQLNFSMRTTGTFPTMAVQMTAIGEESGALDEMLGKVATFYE 361 N R+ V G+ L+ ++ T FP M M A GE SG LD ML + A + Sbjct: 303 NDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQD 362 Query: 362 DEVDNMVDGLTSLMEPMIMAVLGVLVGGLIIAMYLPIFQLGSVV 405 E + + L EP+++ + +V +++A+ PI QL +++ Sbjct: 363 REFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 47.6 bits (113), Expect = 8e-10 Identities = 21/71 (29%), Positives = 40/71 (56%), Gaps = 9/71 (12%) Query: 2 KTQMQKGFTLIELMIVVAIIGILAAIALPAYQDYTVRSNAAAALAEITPGKIGFEQAV-- 59 T Q+GFTL+E+M+V+ IIG+LA++ +P +++ A+++I + E A+ Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDI----VALENALDM 58 Query: 60 ---NEGKTPST 67 + P+T Sbjct: 59 YKLDNHHYPTT 69
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 40.6 bits (95), Expect = 2e-07 Identities = 16/61 (26%), Positives = 34/61 (55%), Gaps = 1/61 (1%) Query: 6 RGFSLIELMTALSIIGILAAIAFPAYQNYTVRSTAAAALAEITPAKAAFE-HAISENRTP 64 RGF+L+E+M + IIG+LA++ P ++ A+++I + A + + + + P Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHYP 67 Query: 65 S 65 + Sbjct: 68 T 68
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 64.1 bits (156), Expect = 9e-13 Identities = 81/322 (25%), Positives = 122/322 (37%), Gaps = 63/322 (19%) Query: 33 VDDGKSTLIGRLLHDSKMIYEDHLEAITRDSKKVGTTGEDVDLALLVDGLQAEREQGITI 92 VD GK+TL LL++S I E S GTT D ER++GITI Sbjct: 12 VDAGKTTLTESLLYNSGAITE-------LGSVDKGTT--------RTDNTLLERQRGITI 56 Query: 93 DVAYRYFSTAKRKFIIADTPGHEQYTRNMATGASTCDLAIILVDARYGVQTQTKRHSFIT 152 F K I DTPGH + + S D AI+L+ A+ GVQ QT+ Sbjct: 57 QTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 153 SLLGIKHIVVAINKMDLM--NFD---QEVFERIKADYLAFADRIELKPSSLHFVPMSALK 207 +GI I INK+D + Q++ E++ A+ + ++EL P+ + + Sbjct: 117 RKMGIPTIFF-INKIDQNGIDLSTVYQDIKEKLSAE-IVIKQKVELYPNMCVTNFTESEQ 174 Query: 208 GDNVVN---------------------RSERA--------PWYEG--------QSLME-I 229 D V+ + E P Y G +L+E I Sbjct: 175 WDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVI 234 Query: 230 LESVEIAGDRNFDDLRFPVQYVNRPNLNFRGFAGTLASGIVRKGDEIAVLPSGKISRVKS 289 + R +L V + R L SG++ D + + KI + Sbjct: 235 TNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEM 294 Query: 290 IVTFDGEL---EQATPGEAVTL 308 + +GEL ++A GE V L Sbjct: 295 YTSINGELCKIDKAYSGEIVIL 316
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 59.6 bits (144), Expect = 5e-12 Identities = 36/178 (20%), Positives = 60/178 (33%), Gaps = 36/178 (20%) Query: 106 ESSLGSAVIMSPEGYLLTNNHVTANAEQIVVALK------------DGRETLARVIGSDP 153 + + S V++ LLTN HV ALK +G T ++ Sbjct: 100 GTFIASGVVVGK-DTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSG 158 Query: 154 ETDLAVLKI-DLAD-------LPAITVGHSDRIRVGDVTLAIGNPFGVGQTVTMGIISAT 205 E DLA++K + T+ ++ +V G P TM + Sbjct: 159 EGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMW--ESK 215 Query: 206 GRNQLGLNTYEDFIQTDAAINRGNSGGALVDAEGNLIGINTAIISESGGSQGIGFAIP 263 G+ L +Q D + GNSG + + + +IGI+ G+ Sbjct: 216 GK-ITYLKGE--AMQYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFN 261
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 223 bits (569), Expect = 2e-67 Identities = 116/460 (25%), Positives = 206/460 (44%), Gaps = 47/460 (10%) Query: 10 KRRTFAIISHPDAGKTTITEKLLLMGKAIAVAGTVKSRKSDRHATSDWMEMEKQRGISIT 69 K +++H DAGKTT+TE LL AI G+V +D +E+QRGI+I Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGT----TRTDNTLLERQRGITIQ 57 Query: 70 TSVMQFPYREHMINLLDTPGHEDFSEDTYRTLTAVDSALMVLDGGKGVEPRTIALMDVCR 129 T + F + +N++DTPGH DF + YR+L+ +D A++++ GV+ +T L R Sbjct: 58 TGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 130 LRDTPIVSFINKLDRDIRDPIELLDEIEAVLKIKAAPITWPIGCYRDFKGVYHLKDDYII 189 P + FINK+D++ D + +I+ L + V + + Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNMCVT 167 Query: 190 VYTPGHGHERTEVKIIEKLDSDEARKHIGDEYERFLEQLELVQGACHEFDQDEFLSGQLT 249 +T E+ + I + ++ D E+++ L + + F + L Sbjct: 168 NFTES---EQWDTVI----EGND------DLLEKYMSGKSLEALELEQEESIRFHNCSLF 214 Query: 250 PVFFGTALGNFGVDHVLDAVVDWAPMPLARAANERVVEPVEEKFTGFVFKIQANMDPKHR 309 PV+ G+A N G+D++++ + + R +E G VFKI+ K R Sbjct: 215 PVYHGSAKNNIGIDNLIEVITNKFYSSTHRGQSE---------LCGKVFKIE--YSEK-R 262 Query: 310 DRIAFMRICSGKYEKGMKLRHARIGKDVRIADALTFFSSEREMLEEAYAGDIIGLHNHG- 368 R+A++R+ SG +R + K ++I + T + E +++AY+G+I+ L N Sbjct: 263 QRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKIDKAYSGEIVILQNEFL 321 Query: 369 --TIQIGDTFTEGENLGFTGIPHFAPELFRRVRLKDPLKSKQLRQGLQELAEEGAT-QVF 425 +GDT P P L V P + + L L E+++ + + Sbjct: 322 KLNSVLGDT-KLLPQRERIENPL--PLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYY 378 Query: 426 FPERNNDIILGAVGVLQFDVVASRLKEEYKVECAYEAINV 465 ++IIL +G +Q +V + L+E+Y VE + V Sbjct: 379 VDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTV 418
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 593 bits (1531), Expect = 0.0 Identities = 228/565 (40%), Positives = 347/565 (61%), Gaps = 13/565 (2%) Query: 407 QVNGIAASPGIAIGPVLVRKPQVIDYPKRGESPV-IELQRLDAALDKVHADIGTL---ID 462 ++ GIAAS G+AI + +D K + V E+++L AAL+K ++ + + Sbjct: 4 KITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTE 63 Query: 463 ESQVASIRDIFTTHQAMLKDPALREEVQVRLQK-GLSAEAAWMEEIESAAQQQEALHDKL 521 S A +IF H +L DP L + ++ +++ ++AE A E + E++ ++ Sbjct: 64 ASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEY 123 Query: 522 LAERAADLRDVGRRVLACLTGVEAEQAP--DEPYILVMDEVAPSDVATLNAQRVAGILTA 579 + ERAAD+RDV +RVL L GVE E +++ +++ PSD A LN Q V G T Sbjct: 124 MKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATD 183 Query: 580 GGGATSHSAIIARALGIPAIVGAGPGVLGLARNTLLLLDGERGELLVAPSGAQLEQARSE 639 GG TSHSAI++R+L IPA+VG + ++++DG G ++V P+ +++ + Sbjct: 184 IGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEK 243 Query: 640 RAAREERKHLANERRMDAAVTRDGHPVEIAANIGAAGETPEAVAMGAEGIGLLRTELVFM 699 RAA E++K + + + T+DG VE+AANIG + +A G EGIGL RTE ++M Sbjct: 244 RAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLYM 303 Query: 700 NHSQAPNQATQEAEYRRVLEALEGRPLVVRTLDVGGDKPLPYWPMPAEENPFLGVRGIRL 759 + Q P + Q Y+ V++ ++G+P+V+RTLD+GGDK L Y +P E NPFLG R IRL Sbjct: 304 DRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAIRL 363 Query: 760 SLQRPDILETQLRALLASADGRPLRIMFPMVGNIDEWRTAKAMVDRLRVEL------PVA 813 L++ DI TQLRALL ++ L++MFPM+ ++E R AKA++ + +L Sbjct: 364 CLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSD 423 Query: 814 DLQVGIMIEIPSAALIAPVLAQEVDFFSIGTNDLTQYTLAIDRGHPTLSGQADGLHPAVL 873 ++VGIM+EIPS A+ A + A+EVDFFSIGTNDL QYT+A DR + +S HPA+L Sbjct: 424 SIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAIL 483 Query: 874 RLIGMTVEAAHAHGKWVGVCGELAADALAVPLLVGLGVDELSVSARSIALVKARVRELDF 933 RL+ M ++AAH+ GKWVG+CGE+A D +A+PLL+GLG+DE S+SA SI ++++ +L Sbjct: 484 RLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKLSK 543 Query: 934 AACQRLAQQALMLPGAHEVRAFVGE 958 + AQ+ALML A EV V + Sbjct: 544 EELKPFAQKALMLDTAEEVEQLVKK 568
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 37.6 bits (87), Expect = 5e-06 Identities = 14/57 (24%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 1 MRHFRGFTLIELIVTLAVLAILLAIAAPSFQSTIQSNRTQTITND---LTSALQLAR 54 RGFTL+E++V + ++ +L ++ P+ + Q +D L +AL + + Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.6 bits (74), Expect = 3e-04 Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 7/56 (12%) Query: 5 LKMTDHQRGATLIEVLVAMLILSVGLLGLASMQMTALQSNQSAYYRSQATVLAYDI 60 ++ TD QRG TL+E++V ++I+ V LAS+ + L N+ ++ DI Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGV----LASLVVPNLMGNKE---KADKQKAVSDI 49
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 33.3 bits (76), Expect = 6e-04 Identities = 12/46 (26%), Positives = 26/46 (56%) Query: 7 NRQMGLSLIELMVAMLISLILLGGVLQVFLSSKDMYRTNTAVARVQ 52 ++Q G +L+E+MV ++I +L V+ + +K+ AV+ + Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIV 50
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 27.7 bits (61), Expect = 0.019 Identities = 14/36 (38%), Positives = 19/36 (52%) Query: 7 EWLGKVPAHWSVVPFGLAFGYQEGPGIMAVDFRDEG 42 +WLG P WS P G+ EG GI ++ + EG Sbjct: 69 QWLGDKPVSWSPTPDGIWLMNAEGTGITHLNRQKEG 104
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 29.9 bits (67), Expect = 0.025 Identities = 35/195 (17%), Positives = 54/195 (27%), Gaps = 53/195 (27%) Query: 195 SPRIVLLDNQQVKLTEELQAESTVRLFPSIAKLLGESPVTYEELLRHDEVIDQLLILGRA 254 +P IV LDN + V + G++ E R I Sbjct: 442 TPSIVTLDNMEATFN----VGQEVPVLTGSQTTSGDNIFNTVE--RKTVGI--------- 486 Query: 255 KLDVLRQIKPDAAGLVVSTDIE-HARQIAQALEAMGESCQIVTNRTPDAQQLINTFRHSD 313 KL V QI V +IE +A A + N + + N Sbjct: 487 KLKVKPQINEGD---SVLLEIEQEVSSVADAASSTSSDLGATFNT----RTVNNAVLVGS 539 Query: 314 CRWIVAVGMISEGT-----------DIPRLQVCCYLSRIRTELHYRQVLGRVLRRKDGSD 362 +V G++ + DIP V+G + R Sbjct: 540 GETVVVGGLLDKSVSDTADKVPLLGDIP-------------------VIGALFRSTSKKV 580 Query: 363 DQAWLFMLAEPTLRR 377 + L + PT+ R Sbjct: 581 SKRNLMLFIRPTVIR 595
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.5 bits (71), Expect = 9e-04 Identities = 14/57 (24%), Positives = 22/57 (38%) Query: 91 LDDLFVYPQFRGSGVGEALLSELCILAQNTGCGRIDWIVATDNDRGRSFYERSGARI 147 ++D+ V +R GVG ALL + A+ + N FY + I Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 91.8 bits (228), Expect = 2e-23 Identities = 69/341 (20%), Positives = 125/341 (36%), Gaps = 65/341 (19%) Query: 1 MIAVGALLLPLVALTACTEEAEATWKDGLEQELRRVDEASPGKLGVYIKHLGENAEL-RY 59 M + ++ L+A A ++++ + G++G+ L L + Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQ----PLEQIKLSESQLSGRVGMIEMDLASGRTLTAW 56 Query: 60 DA-ERFWYLGSAVKVPIALAVLQGVDDGDFSLDQRLTLEAEDKVDGSGDLVWQDN-GVDY 117 A ERF + S KV + AVL VD GD L++++ +D VD S V + + Sbjct: 57 RADERFPMM-STFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSP--VSEKHLADGM 113 Query: 118 SLRDLLKEMLIESDNTAANMLIRLVGEDELNARTRKSMGGDFEAITSFTQVRRDVYGEVH 177 ++ +L + SDN+AAN+L+ VG T R ++ Sbjct: 114 TVGELCAAAITMSDNSAANLLLATVG-----------------GPAGLTAFLR----QIG 152 Query: 178 PDAAKLDNMQLVELASAPFSKPRYEALARVLNLQADELKAASMEQAYERYYARKLNSSSL 237 + +LD R+E EL A ++++ Sbjct: 153 DNVTRLD---------------RWET----------ELNEAL--------PGDARDTTTP 179 Query: 238 VAYGTMLEKLVRGELLSVESRDLLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLERAC 297 + L KL+ + LS S+ L +M D + + LP KTG A Sbjct: 180 ASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGAR 239 Query: 298 H-IGVIEPQDESRAIVVVACAEALDEGRDAGQLFEQVGQAI 337 + ++ P +++ IVV+ + + Q +G A+ Sbjct: 240 GIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAAL 280
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 105 bits (263), Expect = 4e-28 Identities = 68/341 (19%), Positives = 118/341 (34%), Gaps = 72/341 (21%) Query: 17 LLAALLCASTGQTAIAQEAFEWSGPFLARLAQLDRQTPGHLGVYVKDMQTGISVS-YHGE 75 LLA L A ++ + + Q G +G+ D+ +G +++ + + Sbjct: 11 LLATLPLAVHASPQPLEQ-----------IKLSESQLSGRVGMIEMDLASGRTLTAWRAD 59 Query: 76 EPWYLASTVKVPVAIAVMRRIEQDELTLDSPVALLASDYVDGAGPTNSHAPGKALSVRFL 135 E + + ST KV + AV+ R++ + L+ + D VD + + H ++V L Sbjct: 60 ERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKH-LADGMTVGEL 118 Query: 136 LDQMLIHSDNTASDMLIRLVGIEQVNAVAQELAPEGLGPITSLADVRRLIYGELHPAARQ 195 + SDN+A+++L+ VG P G L RQ Sbjct: 119 CAAAITMSDNSAANLLLATVG-----------GPAG-----------------LTAFLRQ 150 Query: 196 LSGKDFLALRQQPNDAGRLALLPRLLGVERRTLASISLNEAYERYYATPYNSGTLKAYGD 255 + R + LNEA ++ T + Sbjct: 151 IGDNVTRLDRWET-----------------------ELNEALP---GDARDTTTPASMAA 184 Query: 256 VLSALEAGTALGPASTGYLLSVMRRVETGKQRIKAGLPPGTGFAHKTGT-QRARICDAGL 314 L L L S LL M I++ LP G A KTG +R L Sbjct: 185 TLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVAL 244 Query: 315 VDQPDSDSALSTRLVIVACVRGVASAAQAERALRGTGEAVT 355 + + + R+V++ AS A+ + + G G A+ Sbjct: 245 LGPNNK----AERIVVIYLRDTPASMAERNQQIAGIGAALI 281
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 29.8 bits (67), Expect = 0.005 Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Query: 30 FEVLVASAEERRMLTCARGTRITADAMLLDVLAQDFDLIVLPGGMPGAKTLGELEPLAER 89 FE L +E R A++ LL + V+P A+TL +L P A++ Sbjct: 54 FENLTDEQKELIDTVLTVQNREDAESFLLKINP-----YVIPFQEVTAQTLKKLFPKAKK 108 Query: 90 VRQQARAGLDF 100 ++ LD Sbjct: 109 LKLPDMEELDM 119
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.9 bits (223), Expect = 5e-23 Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 1/136 (0%) Query: 2 RILVIEDNRDILANVLDYLELKGYVVDCAQDGLSGLHLAATEHYDLIVLDIMLPGIDGLQ 61 ILV +D+ I + L GY V + + A DL+V D+++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VCKRLREDAGRDTPIIMLTARDALADRLQGLGAGADDYLVKPFALSELVARIEAVLRRSQ 121 + R+++ A D P+++++A++ ++ GA DYL KPF L+EL+ I L + Sbjct: 65 LLPRIKK-ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 GSRKNKLQVGDLQYDL 137 L Sbjct: 124 RRPSKLEDDSQDGMPL 139
>SECA#SecA protein signature. Length = 901 Score = 28.3 bits (63), Expect = 0.050 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 12/68 (17%) Query: 240 ILLSDESRLLMELSDSGRMLSYRSLNRWFGGLQRSAPHPEGVTIDNDG-TLFVVSEPNLF 298 +++ DE GR + R RW GL ++ EGV I N+ TL ++ N F Sbjct: 333 VIIVDEHT--------GRTMQGR---RWSDGLHQAVEAKEGVQIQNENQTLASITFQNYF 381 Query: 299 YSFRRAEG 306 + + G Sbjct: 382 RLYEKLAG 389
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 64.7 bits (157), Expect = 3e-14 Identities = 42/186 (22%), Positives = 73/186 (39%), Gaps = 8/186 (4%) Query: 8 ILLTGANGGIGRVLVERLCAGEARLLLVGRDSLALEALAR------RFPGQVSLVCADLS 61 +TGA GIG + L + A + V + LE + R D + Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 62 QRSGRQTVLAAARRFGALNCVINAAGVNQFSLLEEQDEDAIARLIGVNVTATLQLTHLLL 121 + R G ++ ++N AGV + L+ ++ VN T + + Sbjct: 71 AI--DEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 122 PLLRQQPRALLVNLGSTFGSIGYPGFTAYCASKFALRGFSEALRRELADSHIKVLYVAPR 181 + + +V +GS + AY +SK A F++ L ELA+ +I+ V+P Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 182 ATRTAM 187 +T T M Sbjct: 189 STETDM 194
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 27.2 bits (60), Expect = 0.034 Identities = 14/90 (15%), Positives = 27/90 (30%), Gaps = 9/90 (10%) Query: 95 GLVKQAKAELEKAIELDPQALDGSAYTSLASLYYQVPGWPIGFGDEDKAAALFKQALTLN 154 G + A + LD + L + + G D A + ++ Sbjct: 50 GKYEDAHKVFQALCVLDHYDSR--FFLGLGACRQAM-------GQYDLAIHSYSYGAIMD 100 Query: 155 PDGIDPNYFHGDFLLRQKRYGEARAALEKA 184 + + LL++ EA + L A Sbjct: 101 IKEPRFPFHAAECLLQKGELAEAESGLFLA 130
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.0 bits (218), Expect = 2e-22 Identities = 37/127 (29%), Positives = 63/127 (49%) Query: 2 RILLVEDDRALGEGIRTALKPEGYTVDWLQDGASALHALSHESFELAILDLGLPRLDGLE 61 IL+ +DD A+ + AL GY V + A+ ++ +L + D+ +P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLKRLRAAANPVPVLVLTARDATGDRIAGLDAGADDYLVKPFDVAELKARLRALLRRSFN 121 +L R++ A +PVLV++A++ I + GA DYL KPFD+ EL + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 RPEPSLE 128 RP + Sbjct: 125 RPSKLED 131
>PF06580#Sensor histidine kinase Length = 349 Score = 39.1 bits (91), Expect = 3e-05 Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 19/103 (18%) Query: 374 LLQNLVSNALEY----TPHGGQIEVQLHGDAEQLILAVDDSGPGISAELRPQLFERFFRL 429 L+Q LV N +++ P GG+I ++ D + L V+++G Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------ 306 Query: 430 GGGQGAGLGLSIV-ARIAELHGASVEL-LDSPLGGLRVLVQLP 470 + G GL V R+ L+G ++ L G + +V +P Sbjct: 307 -TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 45.2 bits (107), Expect = 3e-07 Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 17/154 (11%) Query: 328 TTAGIIAASFAFVNLVARPMGGLVSDRFGNRRFVMLAYMLGIAVGFLLMGLMNSKWPLIV 387 GI+ A +A + P+ G +SDRFG RR V+L + G AV + +M W L + Sbjct: 43 AHYGILLALYALMQFACAPVLGALSDRFG-RRPVLLVSLAGAAVDYAIMATAPFLWVLYI 101 Query: 388 AVAITVLCSVFVQGAEGATFGIIPSIKRRVTGQIS-----GMAGAYGNVGAVCYLTLFTF 442 V G GAT + + +T G A G V L Sbjct: 102 --------GRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL 153 Query: 443 ---VTPSQFFMVIAAGAFVSFGLCLLWLKEPEGA 473 +P F AA ++F L E Sbjct: 154 MGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKG 187
>PF06580#Sensor histidine kinase Length = 349 Score = 42.5 bits (100), Expect = 4e-06 Identities = 41/267 (15%), Positives = 84/267 (31%), Gaps = 57/267 (21%) Query: 387 QPLESWQTLLLTTLADLFAASLSLAQLGQKQARLALMEERAVIARELHDSLAQALSAQKL 446 +P+ L L+ + ++ + + L ++ + Q A Sbjct: 108 KPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAE---------IDQWKMASMA 158 Query: 447 QLARLKRLMQKDSGQAQLD--------DSVQQ-IDRGLNSAYRQLRELLTTFRIKVNEPG 497 Q A+L L +AQ++ ++++ I A L L R + Sbjct: 159 QEAQLMAL------KAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSL---R 209 Query: 498 LKPALQATVEE---------------FGANSGLQIINDYHLDHCPLTPNEEVHCLQIIRE 542 A Q ++ + F + + + + P +Q + E Sbjct: 210 YSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPP----MLVQTLVE 265 Query: 543 ALSNVVKHA---EADHCWLKLT-QDEIGTIHVKIEDDGIGISPEEQRAGHYGLIILRERA 598 N +KH + L + GT+ +++E+ G + + GL +RER Sbjct: 266 ---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERL 322 Query: 599 NSLNGN---ISIGLRPGGGTSVHLRFP 622 L G I + + G + P Sbjct: 323 QMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.5 bits (196), Expect = 2e-19 Identities = 45/199 (22%), Positives = 72/199 (36%), Gaps = 13/199 (6%) Query: 5 TSTRILLVDDHPMMRRGLRDLLELEDDLELIGEAGNGEEAIRLALEIEPDLILMDLNMPG 64 T IL+ DD +R L L + N R + DL++ D+ MP Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 65 IDGLETTRRMRDADIDARIVMFTVSDEQSHVLEALRNGADGYLLKDMDAEQLIEQIRIAA 124 + + R++ A D +++ + + ++A GA YL K D +LI I A Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA- 118 Query: 125 TGRMALSPELTQVLAEAIRVRPKPSGQVQFSSLTKREKEVLRLIAKGQSNKMIARKLGIT 184 E + ++ V S+ + VL + + MI G + Sbjct: 119 ------LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMI---TGES 169 Query: 185 EGTVKVHVKNLLHKLGLRS 203 GT K V LH G R Sbjct: 170 -GTGKELVARALHDYGKRR 187
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 78.7 bits (194), Expect = 3e-19 Identities = 30/117 (25%), Positives = 57/117 (48%) Query: 2 RLLLVEDNVPLADELVASLSRNGYAIDWLTDGRDAEYQGSSEPYDLIILDLGLPGKPGLE 61 +L+ +D+ + L +LSR GY + ++ ++ DL++ D+ +P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRAWRAGGLTTPVLILTARGSWAERIDGLKAGADDYLTKPFHPEELLLRIQALLRR 118 +L + PVL+++A+ ++ I + GA DYL KPF EL+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>PF06580#Sensor histidine kinase Length = 349 Score = 38.7 bits (90), Expect = 3e-05 Identities = 43/271 (15%), Positives = 81/271 (29%), Gaps = 81/271 (29%) Query: 185 RARQQIAQLQQGQRQQLDQQAPVELQPLVEQIN-HLLSHTEETLQ--------RSRHALG 235 + A++ Q + + Q+A +L L QIN H + + ++ ++R L Sbjct: 141 FKNYKQAEIDQWKMASMAQEA--QLMALKAQINPHFMFNALNNIRALILEDPTKAREMLT 198 Query: 236 NLGHALKTPLAVLGSLVQREELAAHPELQASLQEQLEQIQQRVSRELGR--ARLSVDVLP 293 +L + R L Q SL ++L + + + RL Sbjct: 199 SLSELM------------RYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQF---- 242 Query: 294 GAHFDCDAELPALFDTLAMIHRSDLELRWHAPADCRLPHDREDMLELLGNLLDNACKWA- 352 + + D ++P L+ L++N K Sbjct: 243 --ENQINPAI----------------------MDVQVPP------MLVQTLVENGIKHGI 272 Query: 353 -----SNRVELSIERSSNGFVLLVDDDGPGIPAQQREKVIDRGVRLDETAEGHGLGLGIV 407 ++ L + + L V++ G L T E G GL V Sbjct: 273 AQLPQGGKILLKGTKDNGTVTLEVENTGSLA--------------LKNTKESTGTGLQNV 318 Query: 408 SDILTAWRGE-WSLE-ESPLGGLRVRVALPA 436 + L G ++ G + V +P Sbjct: 319 RERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 43.1 bits (101), Expect = 5e-06 Identities = 44/331 (13%), Positives = 100/331 (30%), Gaps = 12/331 (3%) Query: 617 QTDALVASLDRHDDSEAAHAQQALQEQDQRLQELRDRHVALSTQLRQTQQRQSEVELQLQ 676 T+ + A R Q+ + + L+ ++ LS + + E+ +L Sbjct: 36 NTNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELS 95 Query: 677 ALAPRLLALPVHTRLLEQPEAERSQWLETQLTNLKDQIASASQRQ---QQLLALQQRSET 733 +L E L+ + ++ + L A + Sbjct: 96 NAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAA 155 Query: 734 LQQAWQAAREACVEATQQLARQRDALARDSQQLDEELLAF-AELLPVEQLQRWRENPAQT 792 + + A E + + + + L + L+ L +T Sbjct: 156 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKT 215 Query: 793 FMQLDASIATRLQQLQAQTELAEELRQCEQRRSDEQLQQRHR-QEKQASCSARLSEREKL 851 A++A R L+ E A + + ++ + +QA L Sbjct: 216 LEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNF 275 Query: 852 LLACQQALRTSLGEQSSASAWQQQLDAAIQTARQAQTAIDQQLNESKLGLTRLHSEQQNC 911 A ++T E+++ A + L+ Q + ++ + L+ S+ ++ Sbjct: 276 STADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASR-------EAKKQL 328 Query: 912 RQRHAELAQERDALNAELASWRADHPQLDDA 942 H +L ++ A S R D +A Sbjct: 329 EAEHQKLEEQNKISEASRQSLRRDLDASREA 359 Score = 34.7 bits (79), Expect = 0.002 Identities = 62/407 (15%), Positives = 127/407 (31%), Gaps = 34/407 (8%) Query: 314 RQQELEPLLGKAAESLTRLQHEAQSLQQRLDSLQRQCEAAGNDLRAAEQARQTAEPRLAQ 373 + +L + L E + +++L + + ++ E + E L Sbjct: 72 KNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEG 131 Query: 374 ARREEERLSHLNADLASIREESAQADAAASAGEATLKQLGDQQQRAAEQLATLTQQLETS 433 A S L + + A A + L LE Sbjct: 132 AMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEAR 191 Query: 434 AAL--QPLCVAWGGYRPRLQQAVQLAARLQQGQSELPALQAQAEAAESQQSLAREALDNL 491 A + L A + L A + L+ E A + + + L Sbjct: 192 QAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTL 251 Query: 492 QRERDSELGLAEQLAGLHRQLDEWRQAERETDALQQLWAQQLTLTASQHELSNANSRQQA 551 + E+ + +L + ++ ++ L A++ L A + +L + + A Sbjct: 252 EAEKAALEARQAELEKALEGAMN--FSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNA 309 Query: 552 ELDSL---VPLGKQVRNDRDAAEQALKVTLALLERQRLARSENVEALRASLVPGEPCPVC 608 SL + ++ + +A Q L+ + E R + +++A R + E Sbjct: 310 NRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLE----- 364 Query: 609 GSDEHPWQQTDALVASLDRHDDSEAAHAQQALQEQDQRLQELRDRHVALSTQLRQTQQRQ 668 +E ++ + + Q LR A +Q ++ Sbjct: 365 ----------------------AEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKAL 402 Query: 669 SEVELQLQALAPRLLALPVHTRLLEQPEAERSQWLETQLTNLKDQIA 715 E +L AL L +L E+ +AE LE + LK+++A Sbjct: 403 EEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLA 449
>PF01206#SirA family protein Length = 76 Score = 68.6 bits (168), Expect = 2e-19 Identities = 19/68 (27%), Positives = 32/68 (47%) Query: 9 SLDLRGEHCPYNAIATLETLETMQPGQLLEVVTDCSQSVHGIPEDAKAKGYNCLAVEQHG 68 SLD G +CP + +TL TM G++L V+ SV +K G+ L ++ Sbjct: 7 SLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKEED 66 Query: 69 ALFRFLIE 76 + F ++ Sbjct: 67 GTYHFRLK 74
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 28.6 bits (63), Expect = 0.036 Identities = 26/102 (25%), Positives = 37/102 (36%), Gaps = 5/102 (4%) Query: 96 AGAQPESAIRAMLEPHVQAPATPQGNLLESAQAAFAEGRFAEAETQLQQLLSEDNENAAG 155 A E A+R +A +E AA+ F EA + LQ + AA Sbjct: 154 AEEIGEQAVREGNINGPEAYMRFLDREMEGLTAAYNVKLFTEAISSLQIR--MNTLTAAK 211 Query: 156 LILYARCLAERGELAEAETVLDAVKGDEHKQALAGARAQLTF 197 + A + E A AE K +E + A RA T+ Sbjct: 212 ASIEAAAANKAREQAAAEA---KRKAEEQARQQAAIRAANTY 250
>SSBTLNINHBTR#Streptomyces subtilisin inhibitor signature. Length = 144 Score = 27.9 bits (61), Expect = 0.022 Identities = 25/92 (27%), Positives = 35/92 (38%), Gaps = 14/92 (15%) Query: 11 FKPCAVIPVYNHERSLPAVVAALRAADLPCVLVDDGSCPAAAAV----------IDELAE 60 + P A++ H S A A LRA L C G+ PAAAA LA Sbjct: 38 YAPSALVLTVGHGES-AATAAPLRAVTLTCAPTASGTHPAAAAACAELRAAHGDPSALAA 96 Query: 61 QASVFLLRHPRNQGKGGAVISGLREAQRLGFS 92 + SV R + G+ + +RL + Sbjct: 97 EDSVMC---TREYAPVVVTVDGVWQGRRLSYE 125
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 44.4 bits (105), Expect = 2e-06 Identities = 31/147 (21%), Positives = 56/147 (38%), Gaps = 36/147 (24%) Query: 642 LLASLLIFALLCIPFGPGGALRCLAVPLLAA----LASLASLGWLGQSLTLFGLFGLLLV 697 +L L+++ L +R +P +A L + A L G S+ +FG++L Sbjct: 349 MLVFLVMYLFL-------QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLA 401 Query: 698 TAIGVDYAILMRE----------------------QVGGAAVSLVGTLLAATTTWLSFGL 735 + VD AI++ E Q+ GA LVG + + ++ Sbjct: 402 IGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGA---LVGIAMVLSAVFIPMAF 458 Query: 736 LAVSSTPAVSNFGLTVSLGLAFSFFLA 762 S+ F +T+ +A S +A Sbjct: 459 FGGSTGAIYRQFSITIVSAMALSVLVA 485 Score = 31.7 bits (72), Expect = 0.014 Identities = 25/110 (22%), Positives = 43/110 (39%), Gaps = 8/110 (7%) Query: 605 AALEQIAEGVPGTTLVDQPARLNQLFAATKLQAGELKLLASLLIFALLCIPFG----PGG 660 A +E +A +P D Q + QA L ++ +++F L + P Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGN-QAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 661 ALRCLAVPLLAALASLASLGWLGQSLTLFGLFGLLLVTAIGVDYAILMRE 710 + L VPL + L + Q ++ + GLL + AIL+ E Sbjct: 900 VM--LVVPL-GIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVE 946
>SSPAKPROTEIN#Invasion protein B family signature. Length = 133 Score = 29.1 bits (65), Expect = 0.016 Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 264 MRQALATAGCTPEEIDYLNLHGTATAHNDAMESLAVATL 302 +R +L T GC P I L+ H T D+M ++ +A + Sbjct: 10 VRDSLFTIGCPPSIITDLDSHSAITISLDSMPAINIALV 48
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 38.0 bits (88), Expect = 4e-05 Identities = 21/87 (24%), Positives = 27/87 (31%), Gaps = 1/87 (1%) Query: 333 AQPVIREPLAAAAGGEDDREASVRGATAPMMPAPAPAPAPAPAPVERAQPVPAPPVAAPT 392 A + P A E E P P AP P P + +P P V P Sbjct: 56 APADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPK 115 Query: 393 PAL-AAPVRPNVAERPPAPAAAPASSG 418 + RP APA +S+ Sbjct: 116 RDVKPVESRPASPFENTAPARPTSSTA 142 Score = 34.2 bits (78), Expect = 0.001 Identities = 21/100 (21%), Positives = 28/100 (28%), Gaps = 1/100 (1%) Query: 332 DAQPVIREPLAAAAGGEDDREASVRGATAPMMPAPAPAPAPAPAPVERAQPVPAPPVAAP 391 +PV+ E +EA V P P P P + P A Sbjct: 69 PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK-KVEQPKRDVKPVESRPAS 127 Query: 392 TPALAAPVRPNVAERPPAPAAAPASSGHGAWYASQPGSNY 431 AP RP + A + S G S+ Y Sbjct: 128 PFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQY 167
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 265 bits (679), Expect = 2e-81 Identities = 101/408 (24%), Positives = 170/408 (41%), Gaps = 43/408 (10%) Query: 320 VPWDQALDLVLKTKGLDKRQVGNVLLVAPADEIAARERQEL--------ESQRQIAELAP 371 + W A D+V L+K + L + + A ER QR IA + Sbjct: 199 LSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAMIKQ 258 Query: 372 LRRE--------VVQVNYAKAADIARLFQSVTNT----------QGQTDERGSMAVDDRT 413 L R+ V+ + YAKA+D+ + +++T D+ + +T Sbjct: 259 LDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQT 318 Query: 414 NNIIAYQTQERLDELRRIVAQLDIPVRQVMIEARIVEANVDYDKALGVRWGGTQLFANGR 473 N +I + +++L R++AQLDI QV++EA I E LG++W N Sbjct: 319 NALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWA----NKNAG 374 Query: 474 GAVYGNDDLGDEGGNSGDESSGNFPFVDMGVTNRT---AGIGIGYITDNLILDLELSAME 530 + N L +G V + + GI G+ N + L+A+ Sbjct: 375 MTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNW--AMLLTALS 432 Query: 531 KSGNGEVVSQPKVMTADKETAKILKGSEIPYQEASSSGATSTTF-----VEAALSLEVTP 585 S ++++ P ++T D A G E+P S + + F + L+V P Sbjct: 433 SSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKP 492 Query: 586 QITPDNRIIMEVKVTKDEPDFANDVNGT---PTIRKNEVNAKILVNDGETVVIGGVFSNT 642 QI + +++E++ A + T VN +LV GETVV+GG+ + Sbjct: 493 QINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKS 552 Query: 643 QSRSVDKVPFLGDLPYLGRLFRRDIVADSKSELLIFLTPKILNHQAVA 690 S + DKVP LGD+P +G LFR SK L++F+ P ++ + Sbjct: 553 VSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEY 600 Score = 53.0 bits (127), Expect = 3e-09 Identities = 33/184 (17%), Positives = 72/184 (39%), Gaps = 10/184 (5%) Query: 275 SGEKLSLNFQDIDVRSVLQLIADFTDLNLVASDTVSGNITLRLQN-VPWDQALDL---VL 330 + E+ S +F+ D++ + ++ + ++ +V G IT+R + + +Q VL Sbjct: 26 AAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVL 85 Query: 331 KTKGLDK-RQVGNVLLVAPADEIAARERQELESQRQIAELAPLRREVVQVNYAKAADIAR 389 G VL V + + A + S + VV + A D+A Sbjct: 86 DVYGFAVINMNNGVLKVVRSKD-AKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAP 144 Query: 390 LFQSVTNTQGQTDERGSMAVDDRTNNIIAYQTQERLDELRRIVAQLDIPVRQVMIEARIV 449 L + + + G GS+ + +N ++ + L IV ++D + ++ + Sbjct: 145 LLRQLNDNAG----VGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPLS 200 Query: 450 EANV 453 A+ Sbjct: 201 WASA 204
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.4 bits (68), Expect = 0.025 Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 28/127 (22%) Query: 538 KTDKRAQRQAAAALR---QQLAPHKRQADK----LEKDLATVHEKLAELETSLG----DS 586 + D A R+A L Q+L + ++ L +DL E +LE + Sbjct: 315 RRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQN 374 Query: 587 ALYEVARKDELRQLLAKQAELKVREGELEEA--WLEALETLEA---------------LQ 629 + E +R+ R L A + K E LEEA L ALE L LQ Sbjct: 375 KISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQ 434 Query: 630 AQLEASA 636 A+LEA A Sbjct: 435 AKLEAEA 441
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 30.0 bits (67), Expect = 0.003 Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 2/59 (3%) Query: 76 RQAWRPTAQSDEALRELRETLKTMELQAERHLLARLQTTSDDWAASCEPNLWLKTLAPS 134 R+ W + E R RE T+E + + RL W+A +P WL+ ++P+ Sbjct: 10 RREWLLAQTATECQRHGREA--TLEYPTRQGMWVRLSDAEKRWSAWIKPGDWLEHVSPA 66
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.0 bits (98), Expect = 2e-06 Identities = 25/166 (15%), Positives = 55/166 (33%), Gaps = 5/166 (3%) Query: 109 AEQSLKLAQGIRQVADAADKELLSRQQATATTGKAAAPRQAARKPAPAAKTAAKTAATPA 168 +E + +A+ +Q + +K + TA + A ++ K A++ + Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETK 1093 Query: 169 RTQAAEAAVKPAAKAPAKAPAKAPAKTSASAAASKPAAARPTAGKAPARTRPAATAKPVV 228 TQ E + KA + S+ + + + + PA P V Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTV 1153 Query: 229 APAAAEKVAPAAQASAQPAASKPASKPAAKKPAPRKPAASPQKSSS 274 P +Q + +PA + ++ P + + +S Sbjct: 1154 NIK-----EPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194 Score = 32.3 bits (73), Expect = 0.002 Identities = 31/185 (16%), Positives = 65/185 (35%), Gaps = 19/185 (10%) Query: 28 KACSQAVKDAESALAKLQKQRGKA-----QEKLTKARAKLDEAGSAGKAKAQTKARTRLT 82 KA +Q + A+S + Q + EK KA+ + ++ K +Q + Sbjct: 1077 KANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPK---- 1132 Query: 83 ELEDSLALLQSRQSETLTYLAELKRDAEQSLKLAQGIRQVADAADKELLSRQQATATTGK 142 QSET+ AE R+ + ++ + + Q AD E +++ ++ Sbjct: 1133 ----------QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQP 1182 Query: 143 AAAPRQAARKPAPAAKTAAKTAATPARTQAAEAAVKPAAKAPAKAPAKAPAKTSASAAAS 202 + T AT T +E++ KP + + A+ +++ Sbjct: 1183 VTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSN 1242 Query: 203 KPAAA 207 + Sbjct: 1243 DRSTV 1247 Score = 32.3 bits (73), Expect = 0.003 Identities = 22/120 (18%), Positives = 39/120 (32%), Gaps = 4/120 (3%) Query: 161 AKTAATPARTQAAEAAVKPAAKAPAK---APAKAPAKTSASAAASKPAAARPTAGKAPAR 217 TP QA +V + A+ AP PA + S A K + Sbjct: 994 TTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEK 1053 Query: 218 TRPAATAKPVVAPAAAEKVAPAAQASAQPA-ASKPASKPAAKKPAPRKPAASPQKSSSSR 276 AT A++ +A+ Q ++ S+ + K A+ +K ++ Sbjct: 1054 NEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAK 1113
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.6 bits (64), Expect = 0.046 Identities = 15/76 (19%), Positives = 27/76 (35%) Query: 86 EQTRQLAERERELAARLGRLEQLPSASELEERRRLLATLQSDQQRLSGRVEQVLGASREE 145 EQ + E EL +LEQ+ S + L T + L + Sbjct: 256 EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLT 315 Query: 146 WRLAEAEHLLRMAMLQ 161 LA+ E + ++++ Sbjct: 316 LELAKNEERQQASVIR 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 5e-20 Identities = 29/131 (22%), Positives = 55/131 (41%), Gaps = 5/131 (3%) Query: 3 VLIVDDEPLARERLSRLVGDLDGYRVLEPAASNGEEALTLIEELRPDVVLLDIRMPGLDG 62 +L+ DD+ R L++ + GY V SN I D+V+ D+ MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRA-GYDVR--ITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 63 LQVAAKLCETDAPPAVIFCTAHDEF--ALEAFQVSAVGYLVKPVRPEHLTEALKKAERPN 120 + ++ + V+ +A + F A++A + A YL KP L + +A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 121 RVQLAALTRPA 131 + + + L + Sbjct: 123 KRRPSKLEDDS 133
>PF06580#Sensor histidine kinase Length = 349 Score = 185 bits (470), Expect = 9e-58 Identities = 66/230 (28%), Positives = 118/230 (51%), Gaps = 8/230 (3%) Query: 119 LYLRHALISLIMSGLLLRY-FYLQSQWRRQEQAELR-----ARIESLQARIRPHFLFNSL 172 + +++ + S L + F+ + +Q ++ A++ +L+A+I PHF+FN+L Sbjct: 120 IIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNAL 179 Query: 173 NSIAALVASDPVKAEQAVLDLSDLFRASLAR-PGTLVAWSEELELSRRYLSIEQYRLGDR 231 N+I AL+ DP KA + + LS+L R SL V+ ++EL + YL + + DR Sbjct: 180 NNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDR 239 Query: 232 LQMDWQVDGVPDDLPIPQLTLQPLLENALVYGIQPRIEGGVVSVTADYVDGTFQLVVSNP 291 LQ + Q++ D+ +P + +Q L+EN + +GI +GG + + +GT L V N Sbjct: 240 LQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 292 FDEVAQTQASRGTRQGLQNIDARLAALFGPLASLSVERREGRHYTCLRYP 341 +A T GLQN+ RL L+G A + + ++G+ + P Sbjct: 300 -GSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.7 bits (77), Expect = 0.002 Identities = 35/165 (21%), Positives = 52/165 (31%), Gaps = 48/165 (29%) Query: 198 QAAKRGLLIAAAGAHNLLFSGPPGTGKTLLASRLPGLLPPLDEQEALEVAAIHSVASHSP 257 Q R L L+ +G GTGK L+A A+H + Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVAR------------------ALHD---YGK 185 Query: 258 LEHWPQRPFRQPHHSASGP------ALVG-------GGSRPQPGEITLAHQGVLFLDEL- 303 PF + A+ P L G G G A G LFLDE+ Sbjct: 186 ---RRNGPF-VAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIG 241 Query: 304 ---PEFDRKVLEVLREPLESGHIVIARARDKVRFPARFQLVAAMN 345 + ++L VL++ + + ++VAA N Sbjct: 242 DMPMDAQTRLLRVLQQG------EYTTVGGRTPIRSDVRIVAATN 280
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.3 bits (68), Expect = 0.018 Identities = 15/77 (19%), Positives = 31/77 (40%), Gaps = 15/77 (19%) Query: 510 STSPSAPRTAGGWQRRLRTLMLFPRRA-HVVRFITEVVRPAYEDIAEEMRKQGYVVEISE 568 +T+P+ P ++ + + + R +P Y A+ +R +G V Sbjct: 131 NTAPARPTSSTATAATSKPVTSVASGPRALSR-----NQPQYPARAQALRIEGQVK---- 181 Query: 569 GEDRRLRFEITHDGEPD 585 ++F++T DG D Sbjct: 182 -----VKFDVTPDGRVD 193
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 64.6 bits (157), Expect = 1e-14 Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 11/109 (10%) Query: 93 SGQLDSAAEQLLDSV--LLAARRRDYPVVTVIGHTDTLGHRAANEQVGLRRAQAVAELLR 150 L + LD + L+ V V+G+TD +G A N+ + RRAQ+V + L Sbjct: 227 KATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLI 286 Query: 151 AKGLEAMELRVESHGERNLLVATPDATAEPR---------NRRVEILVR 190 +KG+ A ++ GE N + + R +RRVEI V+ Sbjct: 287 SKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVK 335
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.2 bits (81), Expect = 8e-04 Identities = 25/127 (19%), Positives = 43/127 (33%), Gaps = 28/127 (22%) Query: 167 QRKGSGVTFADVIGAAEAKQALSDVTAYLRDPAAYARLGARPPKGVLLTGEPGTGKTQLA 226 + + ++G + A Q + V + +++TGE GTGK +A Sbjct: 128 KLEDDSQDGMPLVGRSAAMQEIYRV----------LARLMQTDLTLMITGESGTGKELVA 177 Query: 227 KALASES---NASFIQVTGSDFS-----SMYFGV-------GIQKVKSLFRTARKQAPCI 271 +AL N F+ + + S FG + F A Sbjct: 178 RALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGT--- 234 Query: 272 IFIDEID 278 +F+DEI Sbjct: 235 LFLDEIG 241
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 28.9 bits (65), Expect = 0.013 Identities = 12/43 (27%), Positives = 20/43 (46%) Query: 57 LLFFSGWLGAWQLLLVQWATFIVLAVLFRMPGLTSRLIPRSVR 99 +L + L L W VLA++ P L+ R +P+ V+ Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVK 43
>cloacin#Cloacin signature. Length = 551 Score = 36.2 bits (83), Expect = 1e-04 Identities = 21/53 (39%), Positives = 24/53 (45%), Gaps = 1/53 (1%) Query: 196 GGGRGGRGGGRRALLLGALLG-GMGRGGGFGGGGFGGGGFGGGGGGFGGGGAS 247 GG G G G G G+ GGG G G GG G GGG G GG ++ Sbjct: 31 GGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83 Score = 35.1 bits (80), Expect = 2e-04 Identities = 17/33 (51%), Positives = 18/33 (54%) Query: 217 GMGRGGGFGGGGFGGGGFGGGGGGFGGGGASGG 249 G G G G GG G G GGG G GGG +GG Sbjct: 47 GGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGG 79 Score = 30.8 bits (69), Expect = 0.005 Identities = 22/77 (28%), Positives = 23/77 (29%), Gaps = 26/77 (33%) Query: 196 GGGRGGRGGGRRALLLGALLGGMGRGGGFGGGG-----------------------FGGG 232 G GRG G + G G G GGG GG Sbjct: 4 GDGRGHNTGAHST---SGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGS 60 Query: 233 GFGGGGGGFGGGGASGG 249 G G GGG GG SG Sbjct: 61 GHGNGGGNGNSGGGSGT 77 Score = 28.1 bits (62), Expect = 0.034 Identities = 16/34 (47%), Positives = 16/34 (47%) Query: 216 GGMGRGGGFGGGGFGGGGFGGGGGGFGGGGASGG 249 GG GRG G G GG G GGGAS G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDG 36
>cloacin#Cloacin signature. Length = 551 Score = 27.4 bits (60), Expect = 0.016 Identities = 32/84 (38%), Positives = 37/84 (44%), Gaps = 9/84 (10%) Query: 44 HEQGTMGGSGTGTGMGTGGTGTGSGMDSGAGTGTGHMP---GSGDRPATTPGSDRGTGVD 100 H G SG G G G G G G G+G + + P GSG GS G G Sbjct: 9 HNTGAHSTSGNING-GPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNG-- 65 Query: 101 AGGDGASGEQGTTGTGGEGGARGA 124 GG+G SG G +GTGG A A Sbjct: 66 -GGNGNSG--GGSGTGGNLSAVAA 86 Score = 27.0 bits (59), Expect = 0.027 Identities = 17/61 (27%), Positives = 27/61 (44%) Query: 12 AGLISGAAFAAGNTGTGTDAGTGTHDSMGHGTHEQGTMGGSGTGTGMGTGGTGTGSGMDS 71 G G+ +++ N G +G+G H G G G G SG G+G G + + + Sbjct: 31 GGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAF 90 Query: 72 G 72 G Sbjct: 91 G 91 Score = 26.2 bits (57), Expect = 0.041 Identities = 19/56 (33%), Positives = 23/56 (41%) Query: 23 GNTGTGTDAGTGTHDSMGHGTHEQGTMGGSGTGTGMGTGGTGTGSGMDSGAGTGTG 78 G TG G G + G GSG G G+G G +SG G+GTG Sbjct: 23 GPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG 78
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 78.3 bits (193), Expect = 5e-19 Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 1/120 (0%) Query: 2 KVLVVEDEALLRHHLLTRLGESGHIVDAVPNAEEALYQTHEFNHDLAVIDLGLPGISGLD 61 +LV +D+A +R L L +G+ V NA + DL V D+ +P + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LIRQLRSRGKVFPILILTARGNWQDKVEGLAAGADDYVVKPFQFEE-LEARLNALLRRSS 120 L+ +++ P+L+++A+ + ++ GA DY+ KPF E + AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124
>PF06580#Sensor histidine kinase Length = 349 Score = 37.9 bits (88), Expect = 6e-05 Identities = 24/128 (18%), Positives = 43/128 (33%), Gaps = 29/128 (22%) Query: 345 HVQVDMQLAESCLVPMEQGALMELLGNLLENAYRLCL------GQIRISALPDGDNLLLL 398 Q++ + + + PM L+ L+EN + + G+I + D + L Sbjct: 243 ENQINPAIMDVQVPPM-------LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLE 295 Query: 399 VEDDGPGVPVDQRARIIRRGERLDGQHPGQGIGLAVVKDILDS-YGGELSLG-ESQLGGA 456 VE+ G L G GL V++ L YG E + + G Sbjct: 296 VENTGSLA--------------LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV 341 Query: 457 AFQIRLRA 464 + + Sbjct: 342 NAMVLIPG 349
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 29.2 bits (65), Expect = 0.012 Identities = 19/81 (23%), Positives = 29/81 (35%), Gaps = 1/81 (1%) Query: 202 LVSQSEAVLTYEYVITALRSQRHLERADMALAYSGDQQVLNQVEGVEGEPWRYVVPEEGT 261 V S A + + I A S A+ A A +GD Q G + W P+ Sbjct: 28 FVVPSTAQMAGQLGIEATGSGVCAGPAEQANALAGDVACAEQWLGDKPVSWS-PTPDGIW 86 Query: 262 LLWVDCLSVPSIARNKPLAYR 282 L+ + + + R K Y Sbjct: 87 LMNAEGTGITHLNRQKEGEYT 107
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 443 bits (1141), Expect = e-155 Identities = 165/471 (35%), Positives = 249/471 (52%), Gaps = 27/471 (5%) Query: 8 RVLLVEDDDSLRQLLVEELEDRGLQVRALASAEEAVGSLESWEPALVVSDLRLPGADGMA 67 +L+ +DD ++R +L + L G VR ++A + + + LVV+D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 68 LLRRVKSMQAAPAFLVITAFGSIQQAVAALKEGADEFLTKPLDLEHFGLAVARALETRRL 127 LL R+K + LV++A + A+ A ++GA ++L KP DL + RAL + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 128 RDEVRRFQQLLSDDRFHGMLGRSRVMRGLFDQIRQLARAEGPVLVIGESGTGKELVARAV 187 R + ++GRS M+ ++ + +L + + +++ GESGTGKELVARA+ Sbjct: 125 RPS----KLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 188 HAESERANRPFLAINCAGLPAELLESEFFGHVAGAFTGANRAHKGLFQQADGGTLFLDEI 247 H +R N PF+AIN A +P +L+ESE FGH GAFTGA G F+QA+GGTLFLDEI Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 248 GEMPLPLQAKLLRVLQEGTIRPVGAERELTVDVRIIAASNRPLETEAGREAFREDLFFRL 307 G+MP+ Q +LLRVLQ+G VG + DVRI+AA+N+ L+ + FREDL++RL Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 308 ETFILQVPPLRDREEDLELLAAGFVAHFAARSGRPVRGLAPAVLAQLRRYPFPGNVRELQ 367 L++PPLRDR ED+ L FV + G V+ L ++ +P+PGNVREL+ Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQA-EKEGLDVKRFDQEALELMKAHPWPGNVRELE 359 Query: 368 NAIERAVTFCHGRSIELEHLPSR---------------------IADYRDDNARSAGAEL 406 N + R I E + + I+ ++N R A Sbjct: 360 NLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 407 LAQLSDGPLLP-TLEELELRYIEHVLKLVDGNKRRAAALLGIGRRTLYRRL 456 L L L E+E I L GN+ +AA LLG+ R TL +++ Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKI 470
>PF06580#Sensor histidine kinase Length = 349 Score = 36.8 bits (85), Expect = 2e-04 Identities = 41/221 (18%), Positives = 75/221 (33%), Gaps = 58/221 (26%) Query: 247 ERQVAEQQTREEQLQARLRQSQQLAAVGRLAAGV-AHELGSPLSVIDGKAQRVLRDDELG 305 + + + + ++ + +++Q +A L A + H + + L+ I +L D Sbjct: 141 FKNYKQAEIDQWKMASMAQEAQLMA----LKAQINPHFMFNALNNI---RALILEDPT-- 191 Query: 306 ETHRRALLQIRQQVARLSAIVRQLLDFGRAAGSPPRSVP-AEVLAHSAAAAVADELAALQ 364 + R+ + LS ++R L S R V A+ L V L Sbjct: 192 --------KAREMLTSLSELMRYSLR-----YSNARQVSLADELTV-----VDSYLQLAS 233 Query: 365 VR------LELLAPAQTVYCRVDPPRFEQALTNLLRNA-----AQASPGGLVRLSWWQDG 413 ++ E + +V P + L+ N AQ GG + L +D Sbjct: 234 IQFEDRLQFENQINPAIMDVQV--PPM--LVQTLVENGIKHGIAQLPQGGKILLKGTKDN 289 Query: 414 NELLLQVEDDGPGVAEANRAALFEPFFTTKAVGEGSGLGLA 454 + L+VE+ G K E +G GL Sbjct: 290 GTVTLEVENTGSLAL--------------KNTKESTGTGLQ 316
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.1 bits (195), Expect = 4e-19 Identities = 26/149 (17%), Positives = 54/149 (36%), Gaps = 2/149 (1%) Query: 6 RVLIVEDDPMVMRLNVDYLARLDGIELVGQCESVPAALELLEREPVDLLLLDVYLRNRSG 65 +L+ +DD + + L+R V + + DL++ DV + + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 66 LEVLRHLRAQDRNTDAVLITAASEIETVRAAQRLGARDYLVKPFSFERFRDAIEACRRAR 125 ++L ++ + ++++A + T A GA DYL KPF I Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 126 ESLARLPDQLGQGDIDRLFSQPAAADARR 154 + + Q + + A + R Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYR 151
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 1e-16 Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Query: 730 QGETVLVVEDDPAVRLLVIDVLEMLGYQALEAADGNAAIRILESSAAVDMLVTDVGLPGM 789 G T+LV +DD A+R ++ L GY ++ R + ++ D++VTDV +P Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI-AAGDGDLVVTDVVMPDE 60 Query: 790 NGRQLADAARQQRPGLPVLFMTGYAKQAASSDFLEPG-MDMISKPFNLDALAKRV 843 N L ++ RP LPVL M+ + E G D + KPF+L L + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.028 Identities = 7/41 (17%), Positives = 15/41 (36%), Gaps = 2/41 (4%) Query: 205 ASKQSYGPALID-DDTPPPAHARFRWSRLALLVAVGAVLWA 244 + + PA ++ +TP R + V A + + Sbjct: 36 KDENEFLPAHLELIETPVSRRPRLVA-YFIMGFLVIAFILS 75
>PF06580#Sensor histidine kinase Length = 349 Score = 32.5 bits (74), Expect = 0.007 Identities = 51/268 (19%), Positives = 91/268 (33%), Gaps = 63/268 (23%) Query: 569 VLAGTHVDIDALKRVEAELRAATLQAQAASEAKGRLL-SGIS-HELRTPLNAILGFAQLM 626 + + + K + A A EA+ L + I+ H + LN I L+ Sbjct: 130 MWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNI---RALI 186 Query: 627 RMDCDDSSQSEAAEYLDEILLASRHLNQLLGEILEWSSLQKERPQLELQPVDVCSLMREC 686 D ++A E L L++L+ R L SL E Sbjct: 187 LED-----PTKAREMLT-------SLSELM------------RYSLRYSNARQVSLADEL 222 Query: 687 AELIA-LEVQQ----RGLQLDLSLPDDGLLVLAEPRRLRQVLLNLLSNAMKYNVPN---- 737 + + L++ LQ + + ++ + P L Q L+ N +K+ + Sbjct: 223 TVVDSYLQLASIQFEDRLQFENQINPA-IMDVQVPPMLVQTLV---ENGIKHGIAQLPQG 278 Query: 738 GHISLRAETSPGHVRILVEDTGLGIDQAQQAQVFEPFQRLGRENSMIQGTGIGLSLCLEF 797 G I L+ G V + VE+TG + + + TG GL E Sbjct: 279 GKILLKGTKDNGTVTLEVENTGSLALKNTK-----------------ESTGTGLQNVRER 321 Query: 798 ARLMNG---QLGLHSEPGVGSRFWIELP 822 +++ G Q+ L + G + +P Sbjct: 322 LQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 58.3 bits (141), Expect = 6e-11 Identities = 43/146 (29%), Positives = 65/146 (44%), Gaps = 18/146 (12%) Query: 3 VGTAGHIDHGKTALLQALTGQQG---------------DRRREERERGITIDLGYVYADL 47 +G H+D GKT L ++L G D ER+RGITI G Sbjct: 6 IGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW 65 Query: 48 GEGSLTGFIDVPGHERFVHNMLAGASGIDCVLLVVAADDGVMPQTREHLAIVELLGIRRA 107 E + ID PGH F+ + S +D +L+++A DGV QTR + +GI Sbjct: 66 -ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT- 123 Query: 108 LVALTKIDRVETARIAEVQRQIENLL 133 + + KID+ ++ V + I+ L Sbjct: 124 IFFINKIDQ-NGIDLSTVYQDIKEKL 148
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 28.3 bits (63), Expect = 0.037 Identities = 23/117 (19%), Positives = 45/117 (38%), Gaps = 7/117 (5%) Query: 61 LLQELATLDEKRAKLALEEGRMMLDSARQRAISAGVAQPECRQRHGDLVESL-RDLQSET 119 L+ EL K A ++ D R A+ +P RQR +++ L R ++ Sbjct: 210 LVTELNKDTSKSALPGSMVANVVADE-RTNAV-LVSGEPNSRQRIIAMIKQLDRQQATQG 267 Query: 120 RLLVIGRQGEDSGDAIQHIGSQLENVIRTMQRPILVAPGDFSEPQSVMLAFDGSATS 176 VI + + D ++ L + TMQ A + +++++ G + Sbjct: 268 NTKVIYLKYAKASDLVE----VLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNA 320
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 453 bits (1166), Expect = e-159 Identities = 167/484 (34%), Positives = 233/484 (48%), Gaps = 54/484 (11%) Query: 3 GQVIFIDDEAAIRQAVQQWLELSGFQVRTFSRAREALTALDRDFPGVLISDVRMPDLDGL 62 ++ DD+AAIR + Q L +G+ VR S A + ++++DV MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 GLLEQLVALDADLPVIMVTGHGDVPMAVQALRQGAYDFIEKPFTPERLLDSVRRAMDKRR 122 LL ++ DLPV++++ A++A +GAYD++ KPF L+ + RA+ + + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 123 LVCENRQLREQFARKGRIESQLLGVSRAMDNLRRQVLELAGTDVNVLIRGETGSGKEQVA 182 + + L+G S AM + R + L TD+ ++I GE+G+GKE VA Sbjct: 124 R------RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 183 RCLHDFSPRAGGPFVALNCAAIPETIFESELFGHESGAFTGAQGKRIGRIEHAAGGTLFL 242 R LHD+ R GPFVA+N AAIP + ESELFGHE GAFTGAQ + GR E A GGTLFL Sbjct: 178 RALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFL 237 Query: 243 DEIESMPLAQQVKLLRVLQEKTLERLGSNRSIEVDLRVISAAKPDLLEEVRGGRFREDLL 302 DEI MP+ Q +LLRVLQ+ +G I D+R+++A DL + + G FREDL Sbjct: 238 DEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLY 297 Query: 303 YRLNVAELHIPPLRERREDIPLLFEHFASQAAQRHGRAAPPVTPGELTQLLAHDWPGNVR 362 YRLNV L +PPLR+R EDIP L HF QA + G L + AH WPGNVR Sbjct: 298 YRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVR 356 Query: 363 ELINAAERHAL-----------------------------------------------GL 375 EL N R Sbjct: 357 ELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYF 416 Query: 376 SAPAPASSGGQSLAEQMEAFEAQCLHNALQQCKGNITEVMTQLQLPRRTLNEKMQRHGLS 435 ++ A + E + AL +GN + L L R TL +K++ G+S Sbjct: 417 ASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476 Query: 436 RSDY 439 Sbjct: 477 VYRS 480
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.9 bits (153), Expect = 3e-12 Identities = 42/185 (22%), Positives = 74/185 (40%), Gaps = 19/185 (10%) Query: 692 TILVVEDDLPVQATVIELLTGLGYSVLRANDAQSALSILQSGLPIDLLFTDVVMPGPLSS 751 TILV +DD ++ + + L+ GY V ++A + + +G DL+ TDVVMP ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDG-DLVVTDVVMPD-ENA 62 Query: 752 TELARQARLLLPDIAVLFTSGYTRNAVVHGGRLDPGVELLSKPYRQEDLARKVRQLLGAT 811 +L + + PD+ VL S + L KP+ +L + + L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 812 ---HSEERAAPQQWVMVVEDQPQLLALTCEMVEE----------LGHRACGYANAELAAQ 858 S+ Q + +V + + ++ G G EL A+ Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEI-YRVLARLMQTDLTLMITGESGTG---KELVAR 178 Query: 859 ALHEQ 863 ALH+ Sbjct: 179 ALHDY 183 Score = 50.2 bits (120), Expect = 3e-08 Identities = 20/111 (18%), Positives = 45/111 (40%), Gaps = 6/111 (5%) Query: 823 VMVVEDQPQLLALTCEMVEELGHRACGYANAELAAQALHEQRFDQLLLDVNLPGRSGPEF 882 ++V +D + + + + G+ +NA + + D ++ DV +P + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 883 AAEALATQPWLRLVFVSGEGRIESKLPAR------SLPKPFSFDQLAEILQ 927 +P L ++ +S + + + A LPKPF +L I+ Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>FLAGELLIN#Flagellin signature. Length = 507 Score = 44.6 bits (105), Expect = 3e-07 Identities = 32/148 (21%), Positives = 61/148 (41%), Gaps = 2/148 (1%) Query: 1 MRISNAQITAMM-HGSLNNSSEKLGKLMQQMASGERMLVPSDDPISAVRVLRIQREEASL 59 I N +++ +LN S L +++++SG R+ DD R L Sbjct: 2 QVI-NTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 60 TQYRTNIANVSGNLSKQEANLKAASDSMLSIRDLLLWAANGSNTDEDLSAIANELEALEN 119 TQ N + E L ++++ +R+L + A NG+N+D DL +I +E++ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 120 TVLSFANVRDEEGRYLFSGTRSNQPAIA 147 + +N G + S + + Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQMKIQVG 148
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 158 bits (401), Expect = 5e-45 Identities = 96/350 (27%), Positives = 157/350 (44%), Gaps = 18/350 (5%) Query: 2 SVLSQIGYSGVRASQIALTATGQNIANVNTPGFSR----LAPEMHSVGGQTASSIGGGVQ 57 S L SG+ A+Q AL NI++ N G++R +A ++G +G GV Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAG--GWVGNGVY 58 Query: 58 VSSIRRLSNDFQNQQLWRASTDKNYYGTSQQYLTALEGLIHSEGSSVSVGLDNFFAALSE 117 VS ++R + F QL A T + + ++ ++ ++ + SS++ + +FF +L Sbjct: 59 VSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQT 118 Query: 118 ASSTPESIALRQQIIGEAKQLAQRFNGLNGNIGTQLNALQGQRVAMVAEINGLSGNIAEL 177 S E A RQ +IG+++ L +F + + Q + A V +IN + IA L Sbjct: 119 LVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASL 178 Query: 178 NAEILKMES--AGRDTATLRDYRENLIKDLSQYAGIRVQEVADGTLTVSLANGQPLVAGT 235 N +I ++ AG L D R+ L+ +L+Q G+ V GT +++ANG LV G+ Sbjct: 179 NDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGS 238 Query: 236 TAGQLRVEQNLAGEQELTLVF----AKTTFPLVQEGLGGSLGALYDMEYGALRPAQADLH 291 TA QL + A T+ + A + GSLG + L + L Sbjct: 239 TARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLG 298 Query: 292 DMAAALAQMVNDTLAGGFDLNGNPGQPLF------VYTPGSTSGMLAVTA 335 +A A A+ N GFD NG+ G+ F V G +A+ A Sbjct: 299 QLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGA 348 Score = 83.1 bits (205), Expect = 4e-19 Identities = 43/131 (32%), Positives = 69/131 (52%), Gaps = 2/131 (1%) Query: 328 SGMLAVTALTPEQLAFSSAGQSGTGEVGNNENLLALLELKSAKVNVAGSDVPLNDAYAGL 387 ++ + L ++ + A + G+ +N N ALL+L+S G NDAYA L Sbjct: 417 DAIVNMDVLITDEAKIAMASEEDAGD-SDNRNGQALLDLQSNS-KTVGGAKSFNDAYASL 474 Query: 388 VGRVGSASRQNKADLAAATVVAEQAQAQRDSVSAVNLDEEAVNLMAYEQAYQANMKVIST 447 V +G+ + K A V Q Q+ S+S VNLDEE NL ++Q Y AN +V+ T Sbjct: 475 VSDIGNKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQT 534 Query: 448 SNDLFNAVLAM 458 +N +F+A++ + Sbjct: 535 ANAIFDALINI 545
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 51.6 bits (123), Expect = 2e-09 Identities = 44/204 (21%), Positives = 72/204 (35%), Gaps = 39/204 (19%) Query: 8 QHLNAMRARHDGPSAARRQQLEMVSEQFEAMFLQQILKQMRKAGDVLSAGNPMRSRELDT 67 Q LN ++A+ AA + V+ Q E MF+Q +LK MR D L S Sbjct: 16 QSLNELKAKAGEDPAA---NIRPVARQVEGMFVQMMLKSMR---DALPKDGLFSSEHTRL 69 Query: 68 MRDFYDEVLAETLAGKRQTGIADMLVQQLSGGLDGTAPAPAALGLASAGQGGQHALRGTW 127 YD+ +A+ + + G+A+M+V+Q++ + A + + L Sbjct: 70 YTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPM-------KFPLETVV 122 Query: 128 QRGVDALDNAWAAGKAGFRALVDSVIKQESSGNVAAVSPKGARGLMQLMPGTARDMAAEL 187 + AL V R +PG ++ A+L Sbjct: 123 RYQNQAL--------------------------SQLVQKAVPRNYDDSLPGDSKAFLAQL 156 Query: 188 GLPFDEARLTSDAEYNKRLGSAYL 211 LP A S ++ L A L Sbjct: 157 SLPAQLASQQSGVPHHLILAQAAL 180
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 348 bits (895), Expect = e-121 Identities = 161/367 (43%), Positives = 226/367 (61%), Gaps = 12/367 (3%) Query: 10 LFLASLVLCWQLPAQA--VPLMDLVDIEGIRGNQLIGYGLVVGLDGTGDK-NQVKFTSHS 66 L ++L PAQA + D+ ++ R NQLIGYGLVVGL GTGD FT S Sbjct: 11 LVFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQS 70 Query: 67 VANMIKQFGINLPANVDPKLKNVAAVTVTATVPPSYSPGQSVDVTVSSLGDAKSLRGGQL 126 + M++ GI KN+AAV VTA +PP SPG VDVTVSSLGDA SLRGG L Sbjct: 71 MRAMLQNLGITTQGG-QSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNL 129 Query: 127 LMTPLQGVDGEIYAVAQGALVVGGVNAEGASGSKVAINTSNSGLIPNGATVERMIPTDFT 186 +MT L G DG+IYAVAQGAL+V G +A+G + + + S +PNGA +ER +P+ F Sbjct: 130 IMTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFK 188 Query: 187 ERPDVMLNVRQPSFQTVTRVVDAVDAY----FGKGTATALNATKISIRAPVTSTQRMSFM 242 + +++L +R P F T RV D V+A+ +G A ++ +I+++ P + M Sbjct: 189 DSVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRVA-DLTRLM 247 Query: 243 AMLERLDVEEGRVRPKVVFNSRTGTVVVGEGVRVKAAAVAHGSLTVTISERPQVSQPGPF 302 A +E L VE KVV N RTGT+V+G VR+ AV++G+LTV ++E PQV QP PF Sbjct: 248 AEIENLTVETDTP-AKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPF 306 Query: 303 SQGQTAVVPQSDVAVEQDRNAMFKWPEGASLESIINTINSLGATPDDVMSILQSLERAGA 362 S+GQTAV PQ+D+ Q+ + + EG L +++ +NS+G D +++ILQ ++ AGA Sbjct: 307 SRGQTAVQPQTDIMAMQEGSKVAI-VEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGA 365 Query: 363 LNAELIV 369 L AEL++ Sbjct: 366 LQAELVL 372
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 143 bits (362), Expect = 7e-45 Identities = 68/189 (35%), Positives = 101/189 (53%), Gaps = 11/189 (5%) Query: 44 PTTGGGLFRSGYGG-----SLVSDRRAVRVGDILTVVLDESTQSSKSAGTSFGKESSVGI 98 P G +F+S L DRR +GD LT+VL E+ +SKS+ + ++ Sbjct: 45 PVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNF 104 Query: 99 G---VPTVLGKTYP--DVETSASGEREFKGSAKSSQQNTLRGSIAVSVHRVLPNGTLLIK 153 G VP L + + ASG F G ++ NT G++ V+V +VL NG L + Sbjct: 105 GFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVV 164 Query: 154 GEKALRLNQGDEYIRLTGLVRIDDINRYNQVSSQSVANAKISYAGRGVLNDSNSAGWLTR 213 GEK + +NQG E+IR +G+V I+ N V S VA+A+I Y G G +N++ + GWL R Sbjct: 165 GEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQR 224 Query: 214 FFASPLFPL 222 FF + L P+ Sbjct: 225 FFLN-LSPM 232
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 39.5 bits (92), Expect = 1e-05 Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 25/174 (14%) Query: 115 GELPEDGSRRYASTAELQALAALMQEVAGQVDALANLEVDVVPQGLRILIKDDQQRFMFQ 174 G+ G+R L Q A V A A V Q +K D +F Sbjct: 169 GDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEV-QTKHFTLKSD---VLFN 224 Query: 175 RGSAVLNPHFARLLGVLAGVLAKVE---NKLIISGHTDATPYRLQSGYDNWN--LSGDRA 229 A L P L L L+ ++ +++ G+TD G D +N LS RA Sbjct: 225 FNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRI------GSDAYNQGLSERRA 278 Query: 230 LRARNVLVSAGLPGRSVL--------QVTAQA-DVMPLRPDAPEDGA-NRRVEI 273 + L+S G+P + VT D + R + A +RRVEI Sbjct: 279 QSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEI 332
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 34.0 bits (77), Expect = 8e-04 Identities = 29/133 (21%), Positives = 56/133 (42%), Gaps = 6/133 (4%) Query: 252 HALREHVEIQLQQRQQSASIRLDPPELGSLEIHLSHESGRLSVQLSAANADVARLLQQTS 311 +L +H+ + +Q QQSA +RL P +LG ++I L + + +Q+ + + V L+ Sbjct: 242 QSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAAL 301 Query: 312 DRLRQEL------VAQHFVQVNVQVGADGQSGRQGQSQQAHDGDAVLAATTPARAAAVED 365 LR +L + Q + G + +Q QSQ+ + + + V Sbjct: 302 PVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVSL 361 Query: 366 GGARSAGRSSDVL 378 G + D+ Sbjct: 362 QGRVTGNSGVDIF 374
>cloacin#Cloacin signature. Length = 551 Score = 30.1 bits (67), Expect = 0.003 Identities = 19/94 (20%), Positives = 37/94 (39%), Gaps = 5/94 (5%) Query: 38 ERDSVEIDRLNLQITTRVETIGARAQ----RRAKVLSAFRLQADADGMQRLLGSYPDEQA 93 ER E+++ N + E Q R++++ +A + ADA + + + Sbjct: 324 ERARAELNQANEDVARNQERQAKAVQVYNSRKSELDAANKTLADAIAEIKQFNRFAHDPM 383 Query: 94 VRLRQSWQQLGVLASQCQ-QINERNGKLLAMHHE 126 + WQ G+ A + Q +N + A E Sbjct: 384 AGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKE 417
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 56.0 bits (134), Expect = 1e-11 Identities = 42/181 (23%), Positives = 87/181 (48%), Gaps = 6/181 (3%) Query: 38 ALQRAVADGFQEGIDKGYREGLEQGREAGHREGFQRGVEDGKALGLEEGRQQGRRAFDEA 97 +L++ +A + ++GY+ G+ +GR+ GH++G+Q G+ A GLE+G + + Sbjct: 39 SLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEGL----AQGLEQGLAEAKSQQAPI 94 Query: 98 GRPLDRLIEAFEGFRQEYEQARREELLELVQKVARQVIRCELTLHPTQLLTLAEEALNAM 157 + +L+ F+ + L+++ + ARQVI T+ + L+ ++ L Sbjct: 95 HARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQQE 154 Query: 158 PGDQEDVRIQLNPEECARIREL--APERAAAWRLVPDEKLALGECRVLTAQAEADIGCQQ 215 P +++++P++ R+ ++ A WRL D L G C+V + + D Sbjct: 155 PLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVAT 214 Query: 216 R 216 R Sbjct: 215 R 215
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 179 bits (455), Expect = 1e-55 Identities = 82/332 (24%), Positives = 162/332 (48%), Gaps = 2/332 (0%) Query: 25 QLRSVSSLDQAAILMLSMGDEISAGILRNFSREEIISISQAMARLSNVKQPMVSDVISRF 84 + +++ +AAIL++S+G EIS+ + + S+EEI S++ +A+L + + +V+ F Sbjct: 11 DVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEF 70 Query: 85 FDDYKEQSSIKGASRSYLAGMLGKALGGDITRSLLDSIYGEEIRAKMAKMEWLDPKQFAA 144 + Q I+ Y +L K+LG +++++ + DP Sbjct: 71 KELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILN 130 Query: 145 LIAKEHAQMQAVFLAFLPPGMATEVLECMPAERQDELLYRIANLSEVNSDVIAELEQLID 204 I +EH Q A+ L++L P A+ +L +P E Q + RIA + + +V+ E+E++++ Sbjct: 131 FIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLE 190 Query: 205 RSLKVLST-QGSQVRGVKQAADIMNRF-KGNRDQMFELLRAHNEELVGKIEDEMYDFFIL 262 + L LS+ + GV +I+N + + E L + EL +I+ +M+ F + Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDI 250 Query: 263 SRQNQDVLQTLLEVIPLDEWVVALKGAEPELVKAIQGAMPKRQAQQMESINRRQGPVPLS 322 + +Q +L I E ALK + + + I M KR A ++ GP Sbjct: 251 VLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRK 310 Query: 323 RVEQVRKDIMAVVREMSADGELQVQLFREQTV 354 VE+ ++ I++++R++ GE+ + E+ V Sbjct: 311 DVEESQQKIVSLIRKLEEQGEIVISRGGEEDV 342
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 289 bits (741), Expect = 6e-93 Identities = 167/561 (29%), Positives = 260/561 (46%), Gaps = 52/561 (9%) Query: 14 LQLDPRVTLAGMAVIAAALAVAVAFYLWRDNGSFRPLHGAGESFPAAEVMQILDGEALQY 73 L+ +PR+ L +AA+A+ VA LW +R L ++ L + Y Sbjct: 19 LRANPRIPLI--VAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIPY 76 Query: 74 RIHPQSGQILVREDQLAQARLLLNAKGVKVAQPAGYELFDKEEPLGTSQFVQDVRLKRSL 133 R SG I V D++ + RL L +G+ G+EL D+E G SQF + V +R+L Sbjct: 77 RFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQE-KFGISQFSEQVNYQRAL 135 Query: 134 EGELARTVMALKGVQQARVHLAQEENSSFVVSKRAPSKASVMLQLEPGYKLSSDQVGAIV 193 EGELART+ L V+ ARVHLA + S FV +++PS ASV + LEPG L Q+ A+V Sbjct: 136 EGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPS-ASVTVTLEPGRALDEGQISAVV 194 Query: 194 NLVANSVPNLKPEDVGVVDQYGALLSRGLNVGGGPA-QNWQAVEDYQQKAAGNIEQVLAP 252 +LV+++V L P +V +VDQ G LL++ G + D + + IE +L+P Sbjct: 195 HLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRIQRRIEAILSP 254 Query: 253 VLGLGNFRISVAADIDFSQKEETFQSYGDTPRLRNEVLR------NESALDRLALGVPGS 306 ++G GN V A +DF+ KE+T + Y LR +E GVPG+ Sbjct: 255 IVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPGA 314 Query: 307 LSNRPLPP-----------EPDGEEAQQLATENK----GATSLREESTRQMDYDQSVVHV 351 LSN+P PP + + + Q +T G S + T + D+++ H Sbjct: 315 LSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDRTIRHT 374 Query: 352 KHAGFALRQQSVAVVLNSAAAPKGG---WTDEARAEMEAMVRNAVGFKQERGDLLSLSVL 408 K + + SVAVV+N G T + ++E + R A+GF +RGD L++ Sbjct: 375 KMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMGFSDKRGDTLNVVNS 434 Query: 409 PFAAVEQIEQVVPWWENSQIHALAKVGVAGLIALLLLLIVVRPAVRNLTQRNVQALP--Q 466 PF+AV+ +P+W+ L+ L++ I+ R AVR R V+ Q Sbjct: 435 PFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLTRRVEEAKAAQ 494 Query: 467 GEGLEGSLVEPSAPAALEGDARPALASPRESNGPHIFGELNPLSEIRLPAPGSGLELQIE 526 + E + L D L R + RL A E+ + Sbjct: 495 EQAQVRQETEEAVEVRLSKDE--QLQQRRAN--------------QRLGA-----EVMSQ 533 Query: 527 HLQMLAKNDPERVSEVIKHWI 547 ++ ++ NDP V+ VI+ W+ Sbjct: 534 RIREMSDNDPRVVALVIRQWM 554
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 45.4 bits (107), Expect = 9e-10 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 3/105 (2%) Query: 3 SITQVQQDLLGRMQQLAGAAEGQPIRPSSMAANAISGSFEAALRSVDAEQRQASAAMAAV 62 S Q + ++ ++Q A +A Q + +G AAL + Q A Sbjct: 1 SAIQGIEGVISQLQATAMSARAQ--ESLPQPTISFAGQLHAALDRISDTQTAARTQAEKF 58 Query: 63 DSGKSD-DLVGAMIDSQKASVSFSALLQVRNKLTTAFDDVMRMPL 106 G+ L M D QKASVS +QVRNKL A+ +VM M + Sbjct: 59 TLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 372 bits (956), Expect = e-127 Identities = 150/469 (31%), Positives = 224/469 (47%), Gaps = 39/469 (8%) Query: 25 EAACDFLQVGLRRQGCKVERYDDL-DGLVKAAIDQFSLIFVVVGSLPARSLYAQVEALTR 83 A L L R G V + A L+ V +P + + + + + Sbjct: 13 AAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDV-VMPDENAFDLLPRIKK 71 Query: 84 RARNVSVIPVVEYADQEKAAALLEIGCVDYLLSPFSEAQLAALLRRQVCAETAQES---- 139 ++ V+ + A E G DYL PF +L ++ R + + S Sbjct: 72 ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLED 131 Query: 140 -------FVSCSQAGRRLLAMAQRVSLTRAPILITGETGTGKELMARYIHRFSASPDAPF 192 V S A + + + R+ T ++ITGE+GTGKEL+AR +H + + PF Sbjct: 132 DSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPF 191 Query: 193 IAVNCAAIPEQMLESILFGHEKGAFTGAVSAQPGKFELANGGTLLLDEIGELPLGLQAKL 252 +A+N AAIP ++ES LFGHEKGAFTGA + G+FE A GGTL LDEIG++P+ Q +L Sbjct: 192 VAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRL 251 Query: 253 LRVLQEQRVERLGGRREIELNVRIIAATNRDLQQEVAEGRFRADLMFRLDVLPLHISPLR 312 LRVLQ+ +GGR I +VRI+AATN+DL+Q + +G FR DL +RL+V+PL + PLR Sbjct: 252 LRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLR 311 Query: 313 ERKEDVLPLARRFIGKYAPQEAHDELLTEDACRALLQHDWPGNARELENTVQRALVLRNG 372 +R ED+ L R F+ + + + ++A + H WPGN RELEN V+R L Sbjct: 312 DRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQ 371 Query: 373 LFIQPQDLGL----------AAPAAASVRVEKPLTLAAENGKAALRASGKWA-------- 414 I + + AAA EN + + G Sbjct: 372 DVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDR 431 Query: 415 -----EYQHVIDTIRRFDGHKTKAAASLGMTSRALRYRLNAMREQGIEL 458 EY ++ + G++ KAA LG+ LR + +RE G+ + Sbjct: 432 VLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKK---IRELGVSV 477
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 79.2 bits (195), Expect = 3e-22 Identities = 33/83 (39%), Positives = 49/83 (59%) Query: 31 APAAAPAPRQDLSFFGKIPVNVTLEVASAEISLKELMECDTSSVIVLDKLAGEPLDVKVN 90 QD+ IPV +T+E+ +++KEL+ SV+ LD LAGEPLD+ +N Sbjct: 43 GGGDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILIN 102 Query: 91 GTLFAKAEVVVMNGNYGLRIVEL 113 G L A+ EVVV+ YG+RI ++ Sbjct: 103 GYLIAQGEVVVVADKYGVRITDI 125
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 232 bits (594), Expect = 4e-79 Identities = 118/245 (48%), Positives = 165/245 (67%), Gaps = 3/245 (1%) Query: 3 LRRGLSLLGLLLIGLMPLAAQAAGGEITLFNLNDTENGQEFSVKLQILIIMTLLGFLPAM 62 +RR LS+ +LL + PLA G + + GQ +S+ +Q L+ +T L F+PA+ Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQLPG---ITSQPLPGGGQSWSLPVQTLVFITSLTFIPAI 57 Query: 63 LMMMTCFTRFIIVLAILRQAIGLQQSPPNQVLIGIALIVTLLVMRPVWQEIHSQAYEPFQ 122 L+MMT FTR IIV +LR A+G +PPNQVL+G+AL +T +M PV +I+ AY+PF Sbjct: 58 LLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFS 117 Query: 123 NDEITLEQALDSAKGSLAGFMLAQTNKNSLETMVALAGEQLPENLDELDFSLLLPAFVLS 182 ++I++++AL+ L FML QT + L LA + + + +LLPA+V S Sbjct: 118 EEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTS 177 Query: 183 ELKTAFQLGFMIFVPFLVIDLVVASVLMAMGMMMLSPMMISLPFKLMVFVLVDGWALLMG 242 ELKTAFQ+GF IF+PFL+IDLV+ASVLMA+GMMM+ P I+LPFKLM+FVLVDGW LL+G Sbjct: 178 ELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVG 237 Query: 243 TLTTS 247 +L S Sbjct: 238 SLAQS 242
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 46.3 bits (110), Expect = 2e-10 Identities = 20/83 (24%), Positives = 36/83 (43%) Query: 5 DTAVHIVSNAIHVIVLVVCVLIVPSLLGGLLISIFQAATQINEQMLSFLPRLLITLGMLV 64 D V + A+++++++ + + + GLL+ +FQ TQ+ EQ L F +LL L Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 65 FAGHWILRTLSDLFIETFQQAGR 87 W L + A Sbjct: 62 LLSGWYGEVLLSYGRQVIFLALA 84
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 92.5 bits (230), Expect = 7e-25 Identities = 62/249 (24%), Positives = 121/249 (48%), Gaps = 32/249 (12%) Query: 5 QYLQSLLAYWWPFCRIMAVFSLAPMFNHKAISVRVRILLALALTLV-------------- 50 Q+L L Y+WP R++A+ S AP+ + +++ RV++ LA+ +T Sbjct: 8 QWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVPVFS 67 Query: 51 ----------------LGLALLLVFTVFTLIGDVVSTQLGLSMAVFNDPMNGVSSASIIY 94 LG + F G+++ Q+GLS A F DP + + ++ Sbjct: 68 FFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASH-LNMPVLA 126 Query: 95 QLYFILLALLFFAVDGHLVTVSIIYQSFVYWPIGS-GLFYDGLQTIAWSMAWVISAALLI 153 ++ +L LLF +GHL +S++ +F PIG L + + + + + L++ Sbjct: 127 RIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLML 186 Query: 154 ALPIVFCMTLVQFCFGLLNRISPAMNLFSLGFPMAILAGLSLIYLTLPNFAEAYLHLTRD 213 ALP++ + + GLLNR++P +++F +GFP+ + G+SL+ +P A HL + Sbjct: 187 ALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSE 246 Query: 214 LLDKIGVLL 222 + + + ++ Sbjct: 247 IFNLLADII 255
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 300 bits (770), Expect = e-102 Identities = 97/354 (27%), Positives = 177/354 (50%), Gaps = 11/354 (3%) Query: 7 SQEKTEEASEQKLKKSRDDGQVTRSKDVATTVSLLATLLLLKLSAGVFLDGMQQ----SF 62 S EKTE+ + +K++ +R GQV +SK+V +T ++A +L + + + + Sbjct: 2 SGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPA 61 Query: 63 SYSYINFQQSEIGIDDVQVILLHNLLVFVSVLLPLLLTPILV-IAFALVPGGWVFASKNF 121 SY+ F Q+ + ++ + LL F + PLL L+ IA +V G++ + + Sbjct: 62 EQSYLPFSQA------LSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAI 115 Query: 122 APNFGKLNPITGLGRMVGAQNWSELAKSLLKISALLGIAGWQLYYAAPRLIALQRTDIFN 181 P+ K+NPI G R+ ++ E KS+LK+ L + + L+ L I Sbjct: 116 KPDIKKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIEC 175 Query: 182 AIGGAFSLTFDLAFSLLLVFVLFSFIDIPLQRFFFLKKMRMTKQERKEEHKNQEGRPEVK 241 + L + FV+ S D + + ++K+++M+K E K E+K EG PE+K Sbjct: 176 ITPLLGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIK 235 Query: 242 ARIKQLQRQLAQRQITKVIKEADVVIVNPTHYAVALKYDPKKAETPFVIARGVDEMALYI 301 ++ +Q +++ R + + +K + VV+ NPTH A+ + Y + P V + D + Sbjct: 236 SKRRQFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTV 295 Query: 302 RKMAQANALEVIELPPLARAIYYSTQVNQQIPAPLYTAVAHVLTYILQLKAWKQ 355 RK+A+ + +++ PLARA+Y+ V+ IPA A A VL ++ + KQ Sbjct: 296 RKIAEEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEKQ 349
>SECA#SecA protein signature. Length = 901 Score = 31.4 bits (71), Expect = 0.017 Identities = 35/144 (24%), Positives = 58/144 (40%), Gaps = 25/144 (17%) Query: 271 AQQRVGAEIAYDLAQDEPMLRLVQGDV-----GAGKTVVAALAA-LQALEAGYQVALMAP 324 A +RV +D+ Q + L + + G GKT+ A L A L AL G V ++ Sbjct: 74 ASKRVFGMRHFDV-QLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL-TGKGVHVVTV 131 Query: 325 TEILAEQHFLNFSKWLEPLGIEVAWLAGKLKGKARAASLEQIAGGCPMVVGTH------- 377 + LA++ N E LG+ V + A+ + A + GT+ Sbjct: 132 NDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAK-----REAYAADITYGTNNEYGFDY 186 Query: 378 -----ALFQDEVVFKRLALVIIDE 396 A +E V ++L ++DE Sbjct: 187 LRDNMAFSPEERVQRKLHYALVDE 210
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 29.7 bits (66), Expect = 0.019 Identities = 16/48 (33%), Positives = 24/48 (50%) Query: 122 DQQPNTAAVEQFRRLLLRLQISAPYAERLVDWLDPDQQPSGEFGAEDN 169 DQQP T A ++ + LQ++ + V DPDQ+P + DN Sbjct: 7 DQQPQTEAAFNPQQFINNLQVAFLKVDNAVASYDPDQKPIVDKNDRDN 54
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.5 bits (66), Expect = 0.002 Identities = 10/22 (45%), Positives = 17/22 (77%) Query: 10 RGFTLLEVLVALAIFASVSAVV 31 RGFTLLE++V + I ++++V Sbjct: 8 RGFTLLEIMVVIVIIGVLASLV 29
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 85.4 bits (211), Expect = 2e-23 Identities = 37/187 (19%), Positives = 67/187 (35%), Gaps = 26/187 (13%) Query: 4 RARAFTLIELLVVIVLLGILVSVAVLSVGGSSTSRELRDEARRLAALIGVLSDEAVLDSR 63 R R FTL+E++++++L+G+ + +L+ S R A + + + + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAA-QTLARFEAQLRFVQQRGLQTGQ 60 Query: 64 EYGLLVNSEGYRVLRY------DEAATRWLEVERRKVHKVPEWMRLDLELDGTPLELLAP 117 +G+ V+ + ++ L D A R + + + G L L Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGSIAGGKLNLA-- 118 Query: 118 TQREDDRAGLSRDDERTARRAPRLEPQLLILSSGELSPFSLRLSERKPRGGAWLIASDGF 177 + D P +LI GE++PF L L E + G Sbjct: 119 ---FAQGEAWTPGD----------NPDVLIFPGGEMTPFRLTLGE----APGIAFNARGE 161 Query: 178 RLPEAQV 184 LPE Q Sbjct: 162 SLPEPQE 168
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 207 bits (529), Expect = 2e-72 Identities = 75/139 (53%), Positives = 97/139 (69%), Gaps = 3/139 (2%) Query: 6 RTQGGFTLIEIMVVVVILGILAALVVPQVMSRPDQAKVTVAKGDIKAIGAALDMYKLDNF 65 Q GFTL+EIMVV+VI+G+LA+LVVP +M ++A A DI A+ ALDMYKLDN Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNH 64 Query: 66 TYPSTQQGLDALVKKPSGNPQPKNWNRDGYLKRLPKDPWGNDYQYLSPGTQGQFDLYSFG 125 YP+T QGL++LV+ P+ P N+N++GY+KRLP DPWGNDY ++PG G +DL S G Sbjct: 65 HYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLLSAG 124 Query: 126 ADGKPGGSDLNADIGNWDL 144 DG+ G D DI NW L Sbjct: 125 PDGEMGTED---DITNWGL 140
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 457 bits (1178), Expect = e-163 Identities = 206/406 (50%), Positives = 279/406 (68%), Gaps = 3/406 (0%) Query: 1 MAAFEYLALDPRGREQKGLIEADSPRQARQLLREKQWAPLEVKQAKSKEDVSRG---GFS 57 MA + Y ALD +G++ +G EADS RQARQLLRE+ PL V + + + S Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 58 FGRGLSARDLALVTRQLATLVQAALPIEEALRAAAAQSTSAKIKSMLLAVRARVMEGHSL 117 LS DLAL+TRQLATLV A++P+EEAL A A QS + ++ AVR++VMEGHSL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 118 AAALREYPSAFPELYRATVAAGEHAGHLGLVLDQLADYTDQRQQSRQKIQLALLYPVILM 177 A A++ +P +F LY A VAAGE +GHL VL++LADYT+QRQQ R +IQ A++YP +L Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 178 VASLAIVVLLLGYVVPDVVKVFVNTGQELPALTRGLIATSDVVKNWGWLIVLGIIAGVLA 237 V ++A+V +LL VVP VV+ F++ Q LP TR L+ SD V+ +G ++L ++AG +A Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 238 MRAALRDPALRLRWHAFILRIPLIGRLSRATNTARFASTLAILTKSGVPLVEALSIAAAV 297 R LR R+ +H +L +PLIGR++R NTAR+A TL+IL S VPL++A+ I+ V Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 298 IANLRIRERVVEAAQKVREGSSLTRALDATGEFPPMMLHMIASGEKSGELDQMLARTARN 357 ++N R R+ A VREG SL +AL+ T FPPMM HMIASGE+SGELD ML R A N Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 358 QENDLAAQVSLLVGLFEPFMLVFMGAVVLVIVLAILMPILSLNQLV 403 Q+ + ++Q++L +GLFEP ++V M AVVL IVLAIL PIL LN L+ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 31.5 bits (71), Expect = 0.005 Identities = 15/79 (18%), Positives = 36/79 (45%), Gaps = 9/79 (11%) Query: 112 TVQSAIAFTSLARGNIPAAVCSAAASSLIGIFLTPLLVLLLMGAQGEGGSTLDAIGKIVV 171 + +++ S ++ + + +AA +SL+G ++ LV + G + I + Sbjct: 363 AIDASLTTISTVLASVSSGISAAATTSLVGAPVS-ALVGAVTGI-------ISGILEASK 414 Query: 172 QLLLPFIAGQIARRWIGDW 190 Q + +A ++A I +W Sbjct: 415 QAMFEHVASKMADV-IAEW 432
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 32.1 bits (73), Expect = 0.006 Identities = 14/58 (24%), Positives = 22/58 (37%), Gaps = 6/58 (10%) Query: 518 PFAM-RDLSGLDIGQAIRKRQRATLPAHLDFPTVSDKLCAAGM-----LGQKTGAGYY 569 P +M L L Q + R + L + V+ L + + + KTGAG Sbjct: 179 PASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGER 236
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.7 bits (111), Expect = 9e-08 Identities = 24/120 (20%), Positives = 48/120 (40%), Gaps = 4/120 (3%) Query: 10 VLVAYNEPWRADQLCQLVRQLRPGMRVQPAADGHAALATCKRQAPSLLIVDGELDGLDGR 69 +LVA ++ L Q + + G V+ ++ L++ D + + Sbjct: 6 ILVADDDAAIRTVLNQALSRA--GYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 70 QLLRELRRHGPTQRLPCVLISARTDTASVRTVLPLAPAAYLGKPYDLADLRQRLDKLLPR 129 LL +++ P LP +++SA+ + YL KP+DL +L + + L Sbjct: 64 DLLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 76.8 bits (189), Expect = 2e-17 Identities = 59/414 (14%), Positives = 134/414 (32%), Gaps = 91/414 (21%) Query: 1 MKAPAQKTLRRVLFVLVALVVIGLL--AWSELRTDGLGEGFASGNGRI--EATEIDVATK 56 ++ P + R V + ++ +VI + ++ E A+ NG++ ++ Sbjct: 49 IETPVSRRPRLVAYFIMGFLVIAFILSVLGQV------EIVATANGKLTHSGRSKEIKPI 102 Query: 57 LGGRIREISVDEGDFVQPGQVIARMDTEVLDAQLNQARAQVRQAENAILTAQALVTQRES 116 ++EI V EG+ V+ G V+ ++ +A + ++ + QA Q L E Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 117 EKATAEAVVLQRRAELTAAQKR-------HQRTETLVGRNALPRQQLDDDLAAMQSAQAA 169 K + + + + ++ ++ T + LD A + A Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLAR 222 Query: 170 LAASRSQVLS-----------ADAG------IAAARSQVIEAQSALEAAQASVVRLQADI 212 + + + ++ +EA + L ++ + +++++I Sbjct: 223 INRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEI 282 Query: 213 TDSELKTDRVAR--------------------------------------------VQYR 228 ++ + V + Q + Sbjct: 283 LSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLK 342 Query: 229 VAQPGEVLGAGGKLLNLVDLADVY-MTFFLPERQAGRVAMGSEVRLVIDAAPQY---VIP 284 V G V+ L+ +V D +T + + G + +G + ++A P + Sbjct: 343 VHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLV 402 Query: 285 AKVTYVASVAQFTPKTVETESEREKLMFRVKARIDPELLRKHMEQVKTGLPGMA 338 KV + A E +R L+F V I+ L + + GMA Sbjct: 403 GKVKNINLDA--------IEDQRLGLVFNVIISIEENCLSTGNKNIPLS-SGMA 447
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.1 bits (75), Expect = 0.006 Identities = 11/39 (28%), Positives = 16/39 (41%) Query: 33 ARCMVGLIGPDGVGKSSLLALIAGARKLQQGHVQVLDGD 71 V L G G+GKS+L+ + G H + G Sbjct: 595 FDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGK 633
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 54.9 bits (132), Expect = 1e-10 Identities = 42/176 (23%), Positives = 70/176 (39%), Gaps = 5/176 (2%) Query: 200 AALIREREHGTIEHLLVMPVTPFEIMVGKV-WAMGLVVLAAAAFALRFVVEGWLNIPIQG 258 AA R T E +L + +I++G++ WA LA A + G+ Sbjct: 89 AAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWL--- 145 Query: 259 SLWLFAGGAALHLFAATSMGIFFGTVARSMPQLGLLVILTLIPLQILSGGVTPRESMPEL 318 SL AL A S+G+ +A S L + P+ LSG V P + +P + Sbjct: 146 SLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIV 205 Query: 319 VQNIMLVAPTTHFVELAQAILFRSAGPSIVWPQLLALAVIGTVFFLGALSRLRVSL 374 Q P +H ++L + I+ + + AL + + F + + LR L Sbjct: 206 FQTAARFLPLSHSIDLIRPIMLGHPVVDVC-QHVGALCIYIVIPFFLSTALLRRRL 260
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 174 bits (442), Expect = 1e-53 Identities = 85/363 (23%), Positives = 148/363 (40%), Gaps = 58/363 (15%) Query: 1 MRILVTGGAGFIGSALIRHLILDTEHSVLNLDKLT--YAGNL-ESLASVEDNPRYQFLQA 57 M+ LVTG AGFIG + + L L+ H V+ +D L Y +L ++ + P +QF + Sbjct: 1 MKYLVTGAAGFIGFHVSKRL-LEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DIADRERVSEALLEFQPDAIMHLAAESHVDRSIDGPAEFIQTNIVGTYQLLEATRAYWQS 117 D+ADRE +++ + + V S++ P + +N+ G +LE R Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 118 LPAERREAFRFHHISTDEVYGDLHGVDDLFTETTPYA-------PSSPYSASKASSDHLV 170 + S+ VYG P++ P S Y+A+K +++ + Sbjct: 120 ---------HLLYASSSSVYGL--------NRKMPFSTDDSVDHPVSLYAATKKANELMA 162 Query: 171 RAWQRTYGLPVLITNCSNNYGPFHFPEKLIPLVILNALDGKPLPVYGDGSQIRDWLFVED 230 + YGLP YGP+ P+ + L+GK + VY G RD+ +++D Sbjct: 163 HTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDD 222 Query: 231 HARALFKVV------------------SEGVVGETYNIGGHNEQKNIEVVRGICALLEEL 272 A A+ ++ + YNIG +E++ I AL + L Sbjct: 223 IAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNS---SPVELMDYIQALEDAL 279 Query: 273 APSKPAGLARYEDLITFVKDRPGHDLRYAIDASKIERELGWVPQETFQTGLRKTVQWYLD 332 E + +PG L + D + +G+ P+ T + G++ V WY D Sbjct: 280 GI---------EAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330 Query: 333 NLE 335 + Sbjct: 331 FYK 333
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 28.9 bits (64), Expect = 0.040 Identities = 23/108 (21%), Positives = 46/108 (42%), Gaps = 5/108 (4%) Query: 288 RQELGRADASVRHQLRRAKRLLAREPSLLQQEQQAHIDDML---AQSQALKVIYEKRLAL 344 R+E+ R A QL+ A+ R +L ++ + I AQS+ +K+ E + Sbjct: 157 RKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLN 216 Query: 345 QQIWTRTSSNGHDMLAAIKQWVHEAEASGIQSLREFAEHLRTYSLRPS 392 ++ + + +M + A+AS +E E ++ S R + Sbjct: 217 SRLSSSIHARDAEMKTLAGKRNELAQAS--AKYKELDELVKKLSPRAN 262
>PF06580#Sensor histidine kinase Length = 349 Score = 40.6 bits (95), Expect = 2e-05 Identities = 21/108 (19%), Positives = 38/108 (35%), Gaps = 22/108 (20%) Query: 873 LQQVLANLISNAVKFSPQDGTVRLGGERRGDWVRIWVRDQGPGIAPEFRARIFQKFSQAD 932 +Q ++ N I + + PQ G + L G + V + V + G Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------- 306 Query: 933 SSDTRQKGGTGLGLAISKELIEHMHG---RIGFDSEPGHGACFWCELP 977 K TG GL +E ++ ++G +I + G +P Sbjct: 307 -----TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.3 bits (185), Expect = 4e-19 Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 3/115 (2%) Query: 6 RILHVEDDPSIQAVTKLALEAIGGYQVLSCSSGAQALEEVEAFAPEFILLDVMMPGMDGP 65 IL +DD +I+ V AL GY V S+ A + A + ++ DV+MP + Sbjct: 5 TILVADDDAAIRTVLNQALS-RAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 QTLLNLRERIDLERIPVTFMTAKVQPGEIEHLRKLGARDVIIKPFDPMQLAEQIR 120 L +++ +PV M+A+ + GA D + KPFD +L I Sbjct: 64 DLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.6 bits (191), Expect = 7e-20 Identities = 25/121 (20%), Positives = 52/121 (42%), Gaps = 3/121 (2%) Query: 6 RILHVEDVPSIQVVTRIALEKIGGFEVLSCPSGQAALEQVQAFAPDLILLDVMLPQMDGI 65 IL +D +I+ V AL + G++V + + A DL++ DV++P + Sbjct: 5 TILVADDDAAIRTVLNQALSR-AGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 ELVRQLGQLIDLQQIPVVFLTGHLQPERLHELRQLGVRQVLSKPFDPLQLAAQLQQVWEA 125 +L+ ++ + +PV+ ++ + + G L KPFD +L + + Sbjct: 64 DLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 126 E 126 Sbjct: 122 P 122
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.8 bits (150), Expect = 3e-12 Identities = 26/134 (19%), Positives = 56/134 (41%), Gaps = 2/134 (1%) Query: 256 RVLIVDDDAELAARYSLVLRNSQMQVQTLTEPTQVLETMRSFNPEVLLLDVNMPGCSGPE 315 +L+ DDDA + + L + V+ + + + + + ++++ DV MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 316 LAQMIRLHDEWLRVTIIYLSAETDIQRQMAALLKAGDDFITKPISDTALVASVYSHAQRA 375 L R+ + ++ +SA+ + A K D++ KP T L+ + Sbjct: 65 LLP--RIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 376 RSLSTALARDSLTG 389 + + L DS G Sbjct: 123 KRRPSKLEDDSQDG 136 Score = 44.1 bits (104), Expect = 1e-06 Identities = 26/127 (20%), Positives = 54/127 (42%), Gaps = 3/127 (2%) Query: 134 RIYLLEADPVAGCSMALTLRNFGYLVSQWQDFAALQQAVATEPPDALIVSVQ--HDSELE 191 I + + D + L GY V + A L + +A D ++ V ++ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 192 SVASLQQGLDHPLPLLVIHERIDFTSQLAAVRAGAQGFFSRPLDITQLENSLERCLDRQQ 251 + +++ LP+LV+ + F + + A GA + +P D+T+L + R L + Sbjct: 65 LLPRIKK-ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 252 GEPFRVL 258 P ++ Sbjct: 124 RRPSKLE 130
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 1e-12 Identities = 27/120 (22%), Positives = 55/120 (45%), Gaps = 5/120 (4%) Query: 828 KPRILHVEDDDDLRVLLAKQIASLDVELAGAATLHEARQLISAQPFDLAIIDLMLPDGDG 887 IL +DD +R +L + ++ ++ + + I+A DL + D+++PD + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 888 SELFDQLAQSIPPPPVII---FSALDTPIQDNRL-ALRQLVKSRHDGDELAKLIQQLLQH 943 +L ++ ++ P PV++ + T I+ + A L K D EL +I + L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF-DLTELIGIIGRALAE 121
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.6 bits (217), Expect = 2e-23 Identities = 34/122 (27%), Positives = 62/122 (50%), Gaps = 3/122 (2%) Query: 8 RILMVEDEEDIAFLIRYMLERHGFVVDHAADGRQALDHFAQAAPPDLTLMDIMLPYHDGL 67 IL+ +D+ I ++ L R G+ V ++ A A DL + D+++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA-AGDGDLVVTDVVMPDENAF 63 Query: 68 ELIERLRAQAGWESVPVLMLTAKAREVDIVRALELGADDYVTKPFQPEELLARIRRLLRG 127 +L+ R++ +PVL+++A+ + ++A E GA DY+ KPF EL+ I R L Sbjct: 64 DLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 128 RR 129 + Sbjct: 122 PK 123
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 28.7 bits (64), Expect = 0.025 Identities = 19/97 (19%), Positives = 34/97 (35%) Query: 21 TATAEGQVQAQQLDAAEATLRMHLAQHPGDADAQFLLARVLSWQGRPQQALPIYQRLLSQ 80 T T E Q+ + T+ M + + LA G+ + A ++Q L Sbjct: 6 TDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVL 65 Query: 81 QPDNADYLLGEGQALLWAGRPQRALASLERAARIAPD 117 ++ + LG G G+ A+ S A + Sbjct: 66 DHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIK 102
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 135 bits (342), Expect = 2e-39 Identities = 61/334 (18%), Positives = 118/334 (35%), Gaps = 57/334 (17%) Query: 4 LYSLPLLAALLAGAASVQA--EVRVLTSIKPLQLIAAAVQDGVGTPDVLLPASASAHHYS 61 S +L A +G + +++V+ + + I + ++P H Y Sbjct: 11 FLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYE 70 Query: 62 LRPSDVRRIREAELFYWIGPDLESFLPRPLSAREGTTVAVQDLPQLSLRRFGDAHAHDED 121 P DV++ EA+L ++ G +LE+ + ++ ++ Sbjct: 71 PLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVS----------- 119 Query: 122 EHHDHDDHDDHDDHDDHDGHEHDAHGHEEAAHGETAHADEHDHDHRPGALDAHLWLLPAN 181 D D + G E D H WL N Sbjct: 120 -----------DGVDVIYLEGQNEKGKE----------------------DPHAWLNLEN 146 Query: 182 ALVIAERMAADLATADPANAQRYQANASAFTQRVAALDARLKQRFAKV--QNKPFFVFHE 239 ++ A+ +A L+ DP N + Y+ N +T ++ LD K +F K+ + K Sbjct: 147 GIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEG 206 Query: 240 AYDYFEAAYGLRHAGVFTAGGEAQPGARHVAAMRERLQQAGPSCVFSEPPARPRLAETLT 299 A+ YF AYG+ A ++ E + + + E+L+Q +F E R +T++ Sbjct: 207 AFKYFSKAYGVPSAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVS 266 Query: 300 AGLPVKMEELDVLGVGLATDAQGYEKLLEGLGDT 333 + + + TD+ + GD+ Sbjct: 267 QDTNIPI------YAQIFTDSIAEQ---GKEGDS 291
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.0 bits (65), Expect = 0.028 Identities = 21/115 (18%), Positives = 43/115 (37%), Gaps = 20/115 (17%) Query: 10 GLGLWAIFGQAQAAWDVNMRSGATDVSRSVFDLHMAIFWICVVIGVLV--FG---VMIYS 64 LW IFG+ + WD +S + F + ++ ++ G + G ++ Sbjct: 229 PAALWVIFGEDRFHWDATTIG----ISLAAFGILHSLAQA-MITGPVAARLGERRALMLG 283 Query: 65 MIAHRRSKRQHSAHFHENTRVEVLWTVIPLLIL---VGMAVPATRTLIHIYDSSE 116 MIA + + W P+++L G+ +PA + ++ E Sbjct: 284 MIA------DGTGYILLAFATRG-WMAFPIMVLLASGGIGMPALQAMLSRQVDEE 331
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.040 Identities = 19/97 (19%), Positives = 38/97 (39%), Gaps = 4/97 (4%) Query: 114 NETVLPGEIVIISNMPRTDADRQRLEALRAQARLASEGIQQLTPAEAMTVKRHLEVLDYV 173 E+V G++++ +AD + ++ QARL Q L+ + + L++ D Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEP 174 Query: 174 SLETVASHQSTALGVLS----AAAGRQLGNVRSTLEK 206 + V+ + L L + Q L+K Sbjct: 175 YFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 31.9 bits (72), Expect = 0.011 Identities = 34/148 (22%), Positives = 54/148 (36%), Gaps = 15/148 (10%) Query: 523 RHDTVEANSYSEFKAEEHRTTHAD-RKTEIRANDHLTVGNSQHLKIGTGQFIEAGNEIHY 581 R NS++ +K RTT D I ++ L + N ++G+G +A + + Sbjct: 166 RLGQFNGNSFTSYKDSADRTTRVDFNAKNILIDNFLEINN----RVGSGAGRKASSTVLT 221 Query: 582 YAGSKVVIDAGMELTASGGGSFLKLDPSGVTLSGATI--RMNSGGAAGKGSGLKILAPVL 639 S+ + + G+ L L + V L G R+ GA LAP Sbjct: 222 LQASEGITSRENAEISLYDGATLNLASNSVKLMGNVWMGRLQYVGAY--------LAPSY 273 Query: 640 PWLATSAVAGSLTLPALINMSRQLKQAA 667 + TS V G + L QA Sbjct: 274 STINTSKVTGEVNFNHLTVGDHNAAQAG 301
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 400 bits (1029), Expect = e-137 Identities = 139/352 (39%), Positives = 196/352 (55%), Gaps = 37/352 (10%) Query: 183 PAAPVSPCASGYGLIGDSPRMRAVYQLIGKVLHSPVNVLLTGETGTGKELVARAIHDCGF 242 P+ G L+G S M+ +Y+++ +++ + + +++TGE+GTGKELVARA+HD G Sbjct: 126 PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGK 185 Query: 243 RRSKPFVVQNCASLPEQLLESELFGYRKGAFTGADRDRSGLLDAANGGTLFLDEIGDMPL 302 RR+ PFV N A++P L+ESELFG+ KGAFTGA +G + A GGTLFLDEIGDMP+ Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPM 245 Query: 303 LLQAKLLRVLQEGEVRPLGSTETHKVDVRIVAATHRDLRSQVENGLFREDLFYRLSHFPI 362 Q +LLRVLQ+GE +G + DVRIVAAT++DL+ + GLFREDL+YRL+ P+ Sbjct: 246 DAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPL 305 Query: 363 ELPPLRERDEDILRLARHFADKACAFLQRDLCRWSDAALERLAGYAFPGNVRELKGLVER 422 LPPLR+R EDI L RHF +A D+ R+ ALE + + +PGNVREL+ LV R Sbjct: 306 RLPPLRDRAEDIPDLVRHFVQQAEK-EGLDVKRFDQEALELMKAHPWPGNVRELENLVRR 364 Query: 423 AVLLCEGGELLPEHLNLHVEASL------------------------------------D 446 L + E + + + + Sbjct: 365 LTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALP 424 Query: 447 SSLNLRERMERVERSLLMDCLRKNGGNQSQAARELGLPRRTLLYRMERLNIS 498 S + +E L++ L GNQ +AA LGL R TL ++ L +S Sbjct: 425 PSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.3 bits (71), Expect = 0.019 Identities = 28/145 (19%), Positives = 43/145 (29%), Gaps = 22/145 (15%) Query: 549 AQLAREHNAQVANFAADLRARVRGQEQAVEALDRAMRAAAAGLNKPDAPVGVFLLVGPSG 608 A + + + G+ A++ + R + D + ++ G SG Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQT----DLTL---MITGESG 170 Query: 609 VGKTETALALADLLYGGERFLTVINMSEFQEKHSVSRLIGAPPGYVGYGEGGMLTEAVRQ 668 GK A AL D INM+ S L G E G T A + Sbjct: 171 TGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH--------EKGAFTGAQTR 222 Query: 669 KPYSV-------ILLDEVEKADPDV 686 + LDE+ D Sbjct: 223 STGRFEQAEGGTLFLDEIGDMPMDA 247
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 30.1 bits (68), Expect = 0.017 Identities = 47/188 (25%), Positives = 67/188 (35%), Gaps = 35/188 (18%) Query: 22 ADIFLQHGKIAAIGQA--P-----------AGFEAQRTIDGQGLIAAPGLVDLAVALREP 68 ADI L+ G+IAAIG+A P G E I G+G I G +D + P Sbjct: 86 ADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEV---IAGEGKIVTAGGMDSHIHFICP 142 Query: 69 GYSRKGSIASETLAAAAGGITSLCCPPQTRPVLDTAAVT----ELILDRARESGHAKVFP 124 E L + G+T + T P T A T + R E+ A FP Sbjct: 143 ------QQIEEALMS---GLTCM-LGGGTGPAHGTLATTCTPGPWHIARMIEA--ADAFP 190 Query: 125 IG-ALTRNLAGEQLSELVALREAGCVAFGNGLTEFASNRNLRRALEYAATFDLTVIFHSQ 183 + A LV + G + + + L A +D+ V+ H+ Sbjct: 191 MNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEYDVQVMIHTD 250 Query: 184 DRDLAEGG 191 L E G Sbjct: 251 --TLNESG 256
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 28.6 bits (64), Expect = 0.031 Identities = 10/42 (23%), Positives = 18/42 (42%) Query: 293 ADGPQSVILNQVTYGIAIRMAVLSMAMSGQTAQRQIDSESVS 334 A G Q + N G+A+ +++ M A + E V+ Sbjct: 40 ALGLQQIPSNMTLNGVALLLSMFVMWPIMHDAYVYFEDEDVT 81
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 63.1 bits (153), Expect = 9e-14 Identities = 30/181 (16%), Positives = 60/181 (33%), Gaps = 11/181 (6%) Query: 95 APFQDTEVRKVTPPAAPPR-------STQPEPAKTVVTTRSRQPDKADTKQQTQPQPEPQ 147 AP Q V V P P EP + ++ +P+P+P+ Sbjct: 45 APAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPK 104 Query: 148 AAPAFDSSQLSAEIASLEAELAHDVERYAKRPRVSRQNSAATMRDISAWYRDEWRKKVER 207 P Q ++ +E+ A E P ++A + + R Sbjct: 105 PKPVKKVEQPKRDVKPVESRPASPFE--NTAPARPTSSTATAATSKPVTSVASGPRALSR 162 Query: 208 IGNLNYPDEARRQQIYGSLRMLVTINRDGTVQELRVIESSGQPVLDDAALRIVRLAAPFA 267 YP A+ +I G +++ + DG V ++++ + + + +R + Sbjct: 163 N-QPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMR-RWRYE 220 Query: 268 P 268 P Sbjct: 221 P 221
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.1 bits (169), Expect = 7e-17 Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 2/114 (1%) Query: 9 KVMVIDDSKTIRRTAETLLKKVGCDVITAVDGFDALAKIADTHPRIIFVDIMMPRLDGYQ 68 ++V DD IR L + G DV + IA ++ D++MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 69 TCALIKNNSSFKSTPVIMLSSKDGLFDKAKGRIVGSDQYLTKPFSKEELLGAIK 122 IK + PV+++S+++ K G+ YL KPF EL+G I Sbjct: 65 LLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.9 bits (192), Expect = 3e-20 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 2/119 (1%) Query: 2 ARVLIVDDSPTEMYKLTAMLEKHGHVVLKAENGADGVALARQEKPDAVLMDIVMPGLNGF 61 A +L+ DD L L + G+ V N A D V+ D+VMP N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QATRQLTKDSETSHIPVIIVTTKDQETDKVWGKRQGAKDYLTKPVDEATLLKTLNAVLA 120 ++ K +PV++++ ++ + +GA DYL KP D L+ + LA Sbjct: 64 DLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.5 bits (170), Expect = 9e-14 Identities = 26/116 (22%), Positives = 56/116 (48%), Gaps = 2/116 (1%) Query: 2287 TLVMVVDDSVTVRKVTSRLLERNGMNVLTAKDGVDAITQLQERKPDIMLLDIEMPRMDGF 2346 ++V DD +R V ++ L R G +V + + D+++ D+ MP + F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 2347 EVATLVRHDERLKDLPIVMITSRTGEKHRDRALSIGVNEYLGKPYQESVLLEAIQR 2402 ++ ++ + DLP+++++++ +A G +YL KP+ + L+ I R Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 78.2 bits (192), Expect = 7e-19 Identities = 55/165 (33%), Positives = 75/165 (45%) Query: 6 AVICGATAGVGRATAEAFAKAGYRVALIARGEQGLRDTQEQLEALGATVLAISADVADAA 65 A I GA G+G A A A G +A + + L L+A A ADV D+A Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 66 ALDAAASRIEAELGAIDVWVNAAMATVFGPFAALTAEEIRRVTEVTYLGSVHGTLAALRH 125 A+D +RIE E+G ID+ VN A G +L+ EE V G + + + ++ Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 126 MRSRNRGTIVQVGSALAYRAIPLQSAYCGAKFAIRGFIDSLRCEL 170 M R G+IV VGS A +AY +K A F L EL Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.1 bits (195), Expect = 3e-17 Identities = 36/115 (31%), Positives = 52/115 (45%), Gaps = 3/115 (2%) Query: 1046 KILVVDDDVRNVFALTSALEQKGALVEIARNGLEAIDKLQHDTDIDLVLMDIMMPEMDGF 1105 ILV DDD L AL + G V I N + DLV+ D++MP+ + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDENAF 63 Query: 1106 TAMQEIRKDVRFAKLPIIAVTAKAMKDDQDRCLSAGANDYLAKPIDLDRLFSLIR 1160 + I+K LP++ ++A+ + GA DYL KP DL L +I Sbjct: 64 DLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Score = 68.3 bits (167), Expect = 7e-14 Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 2/81 (2%) Query: 900 RILLVEDDALQRESMSRLIEDVDIEITAVEFGAQALEQLRDTVFDCMIIDLKLPDMDGSE 959 IL+ +DDA R +++ + ++ A + D ++ D+ +PD + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 960 LLERMAKEDICSFPPVIVYTG 980 LL R+ K PV+V + Sbjct: 65 LLPRIKKAR--PDLPVLVMSA 83 Score = 58.7 bits (142), Expect = 7e-11 Identities = 29/127 (22%), Positives = 54/127 (42%), Gaps = 5/127 (3%) Query: 779 VLVIEDEPQFARILHDLAHELQYSCLLAQNADDGFDTALQYKPDAILLDMRLPDHSGLTV 838 +LV +D+ +L+ Y + NA + D ++ D+ +PD + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 839 LERLKENPATRHIPVHVVSVE---DRKEAAMQMGAVGYAMKPTTREELKDVFSRLEAKLA 895 L R+K+ A +PV V+S + A + GA Y KP EL + R A+ Sbjct: 66 LPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 896 QKVKRIL 902 ++ ++ Sbjct: 124 RRPSKLE 130
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.2 bits (177), Expect = 6e-16 Identities = 33/159 (20%), Positives = 59/159 (37%), Gaps = 9/159 (5%) Query: 10 LLIVDDLPENLLALDALLQAPGVRVHQAESAEQALELLLRYEFALAILDVQMPGMDGFQL 69 +L+ DD L+ L G V +A + + L + DV MP + F L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 70 AELMRGTERTKQIPIVFVSAAGRELNYAFKGYESGAVDFMHKPLDAHAVRSKVSVFVDLY 129 ++ + +P++ +SA A K E GA D++ KP D + + Sbjct: 66 LPRIK--KARPDLPVLVMSAQN-TFMTAIKASEKGAYDYLPKPFDLTELIGIIG------ 116 Query: 130 RSRKRLARQLEALERSRREQEVLLDELRSTKAELEDAVR 168 R+ R+ LE ++ L+ + + R Sbjct: 117 RALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 53.1 bits (127), Expect = 5e-09 Identities = 43/300 (14%), Positives = 88/300 (29%), Gaps = 23/300 (7%) Query: 21 AQSLDSLTGTPPATEGEAKPAQLSLGEQTQRMVQQTETSNKRAEDLKALLAQAPKEIAEA 80 + + K L + + + + + K L + K ++E Sbjct: 52 LEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEK 111 Query: 81 QRELAKLKASPDE----DPAQRYAKQSVEALEQRLSARVEELSEWQKQFSAANSMIITA- 135 ++ +L+A + + A + L A L+ + A + Sbjct: 112 ASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFS 171 Query: 136 ---QTRPERAQAQISTAQTRIQEINNLLKSGRESGKPLSEERRGLLDAEIVSLSAQIDLR 192 + + +A+ + + R E+ L+ + L+AE +L+A+ Sbjct: 172 TADSAKIKTLEAEKAALEARQAELEKALEGAMNFST-ADSAKIKTLEAEKAALAARKADL 230 Query: 193 RQELAGNSLLQDLGKARRDLLAERIARAEQDTQALQSLINEKRRAESEQTVAEFSARVQQ 252 + L G A+ L A E L+ + SA+++ Sbjct: 231 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA-----MNFSTADSAKIKT 285 Query: 253 AGSDKLLAAESAENLKLSDYLLRATERLNRLNQQNLRTRQQLDTLNQTDQALEEQIAVLE 312 AE L + LN R+ LD + + LE + LE Sbjct: 286 L---------EAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLE 336
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.7 bits (207), Expect = 3e-22 Identities = 25/115 (21%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Query: 4 TILIVDDSQSMRQLVKMTLTGAGHQVIEAVDGRDALTKLTGQKINLIISDVNMPNLDGIG 63 TIL+ DD ++R ++ L+ AG+ V + + +L+++DV MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 LVKAVKANPAYRFTPICMLTTESEQGKKAEGQAAGAKAWIVKPFQPQQLLSAVEK 118 L+ +K A P+ +++ ++ + GA ++ KPF +L+ + + Sbjct: 65 LLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 8e-05 Identities = 20/94 (21%), Positives = 37/94 (39%), Gaps = 11/94 (11%) Query: 591 LVQEAVNNVARHARAR-----TVRILMVCDEHELRLEILDDGRGFDVPEALQGAQSLGLT 645 LVQ V N +H A+ + + D + LE+ + G + + + GL Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA--LKNTKESTGTGLQ 316 Query: 646 SMHERVASFGGD---LRISSLPGMGTRITALLPA 676 ++ ER+ G +++S G L+P Sbjct: 317 NVRERLQMLYGTEAQIKLSEKQG-KVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.9 bits (171), Expect = 3e-16 Identities = 31/132 (23%), Positives = 49/132 (37%), Gaps = 7/132 (5%) Query: 1 MSK-RVALVDDHALVRAGLRALVEDQPGYEVVAEGGDGQDVEAILRQARPDILLLDLSMK 59 M+ + + DD A +R L + GY+V + + D+++ D+ M Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRA-GYDVRITSN-AATLWRWIAAGDGDLVVTDVVMP 58 Query: 60 HMGGLDALRQWHGQYPDVQVLILSMHATADYVLAALRLGARGYLLK----DAAAQELDMA 115 D L + PD+ VL++S T + A GA YL K + A Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 116 LQALSRNESYLS 127 L R S L Sbjct: 119 LAEPKRRPSKLE 130
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 27.2 bits (60), Expect = 0.045 Identities = 11/37 (29%), Positives = 21/37 (56%) Query: 91 VGVLNMTDEAGGDAKLIAVPHDKLSQLYVDVKEYTDL 127 VG+ +++ A + V DK+ Q+Y D+K + D+ Sbjct: 245 VGLAALSNANKPSASPVKVLSDKIIQIYSDIKPFADI 281
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 367 bits (944), Expect = e-129 Identities = 156/358 (43%), Positives = 214/358 (59%), Gaps = 6/358 (1%) Query: 2 RPLVATVDLTALRHNYLLAKQCAPQRKAFAVVKANAYGHGACEAVTALREIADGFAVACL 61 RP+ A++DL AL+ N + +Q A + ++VVKANAYGHG +A+ DGFA+ L Sbjct: 3 RPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGA-TDGFALLNL 61 Query: 62 EEAEDIRRSAPDARILLLEGCFEPAEYLRAAELGLDVAVQDQRQADWLLAANISRPLNVW 121 EEA +R IL+LEG F + + L V Q L A + PL+++ Sbjct: 62 EEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIY 121 Query: 122 LKLDSGMHRLGFTLEGLRDCHERLKGKAQVGELNLISHFACADERGHPLTELQLERYAEL 181 LK++SGM+RLGF + + ++L+ A VGE+ L+SHFA A+ + R + Sbjct: 122 LKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDG--ISGAMARIEQA 179 Query: 182 L-SLEFDNCSLANSAAVLTLPQAHMAWIRPGIMLYGATPFAELS-AQELGLRPVMTLTGA 239 LE SL+NSAA L P+AH W+RPGI+LYGA+P + GLRPVMTL+ Sbjct: 180 AEGLECRR-SLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSE 238 Query: 240 LIAVRDVSEGESVGYGASWVAQRASRIGTVSCGYADGYPRTAPSGTSVVIHGQRVPLAGR 299 +I V+ + GE VGYG + A+ RIG V+ GYADGYPR AP+GT V++ G R G Sbjct: 239 IIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGT 298 Query: 300 VSMDMLAVDLTDLPQAQLGDAVELWGAQMPIDELAQACGTIGYELLTKVTGRVPRRYI 357 VSMDMLAVDLT PQA +G VELWG ++ ID++A A GT+GYEL+ + RVP + Sbjct: 299 VSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRVPVVTV 356
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 30.6 bits (69), Expect = 0.022 Identities = 16/61 (26%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 291 TAVLLNIF-GLRAFGAWVFVALALTAIPASLWASFRRWRQGYFPALLYLCGFGVILGSVN 349 T VL+ + +R FG W+ +AL + + + R + LL+L G I +N Sbjct: 213 TRVLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQEKRRVSFHRRLLHLPLIGRIARGLN 272 Query: 350 L 350 Sbjct: 273 T 273
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.1 bits (182), Expect = 4e-16 Identities = 32/147 (21%), Positives = 62/147 (42%), Gaps = 2/147 (1%) Query: 244 IRVLIIDDSRAQATHTERVLNNAGIVTQTLIEPIQAIGVLAEFQPDLIILDMYMPECLGT 303 +L+ DD A T + L+ AG + +A DL++ D+ MP+ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 304 ELAKVIRQHERYVSVPIIYLSAEDDLDKQLDAMGEGGDDFLTKPIKPSHLIATVRTRATR 363 +L I+ + +P++ +SA++ + A +G D+L KP + LI + Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 364 ARSLKARIVRDSLTGLYNHTHSLQLLE 390 + +++ DS G+ S + E Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAAMQE 148
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 506 bits (1304), Expect = e-180 Identities = 170/475 (35%), Positives = 257/475 (54%), Gaps = 34/475 (7%) Query: 4 RQKALIIDDEPDIRELLEITLGRMKLDTRSARNLKEARELLAREHYDLCLTDMRLPDGSG 63 L+ DD+ IR +L L R D R N +A DL +TD+ +PD + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 64 LELVQYIQQQHPQLPVAMITAYGSLDTAIGALKAGAFDFLTKPVDLNRLRELVSTAL--- 120 +L+ I++ P LPV +++A + TAI A + GA+D+L KP DL L ++ AL Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 121 -RLRAPATEAPVDSR-LLGGSPPMKVLRKQIGKLARSQAPVYISGESGSGKELVARLIHE 178 R + + D L+G S M+ + + + +L ++ + I+GESG+GKELVAR +H+ Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD 182 Query: 179 QGPRAEKTFVPVNCGAIPSELMESEFFGHKKGSFSGAIEDKPGLFQAASGGTLFLDEVAD 238 G R FV +N AIP +L+ESE FGH+KG+F+GA G F+ A GGTLFLDE+ D Sbjct: 183 YGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGD 242 Query: 239 LPLPMQVKLLRAIQEKAVRAVGGAQEVMVDVRILCATHKDLAAEVAAGRFRQDLYYRLNV 298 +P+ Q +LLR +Q+ VGG + DVRI+ AT+KDL + G FR+DLYYRLNV Sbjct: 243 MPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNV 302 Query: 299 IELRVPPLRERREDIRLLADAMLRRLAQECGDSIAHLHPEALAKLESYRFPGNVRELENM 358 + LR+PPLR+R EDI L +++ +E G + EAL ++++ +PGNVRELEN+ Sbjct: 303 VPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVRELENL 361 Query: 359 LERAYTLCDGEEIKAGDLRL---------ADSPGSSENGEASLAQI-------------- 395 + R L + I + ++ +G S++Q Sbjct: 362 VRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGD 421 Query: 396 -----DNLEDHLEEIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGLD 445 + L E+E LI+ AL TR N+ AA LGL ++R ++++LG+ Sbjct: 422 ALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 95.7 bits (238), Expect = 5e-25 Identities = 41/157 (26%), Positives = 71/157 (45%), Gaps = 7/157 (4%) Query: 2 RILVVEDEAKTADYLKRGLEESGYRVEVARNGVDGKYLIEEETFDLVILDVMLPGLDGWE 61 ILV +D+A L + L +GY V + N I DLV+ DV++P + ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LVQVVRRRSAHTPVLFLTARDAVEDRVRGLELGADDYLVKPFSYAELLARVRTLLRRGPP 121 L+ +++ PVL ++A++ ++ E GA DYL KPF EL+ + L P Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE-PK 123 Query: 122 REVERFQVADLELDLLR------RRVSRQGERISLTN 152 R + + + L + + R R+ T+ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTD 160
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 74.3 bits (182), Expect = 1e-18 Identities = 26/114 (22%), Positives = 49/114 (42%), Gaps = 6/114 (5%) Query: 5 RERNKELILKAASEEFAEKGFAASKTSDIAARAGLPKPNVYYYFKSKENLYREVLESIVE 64 + ++ IL A F+++G +++ +IA AG+ + +Y++FK K +L+ E+ E Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 65 PLLEASA--PFNQPGHPAEVLRA----YIRTKIRISRDHACASKVFASEIMHGA 112 + E PG P VLR + + + R +F G Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 32.3 bits (73), Expect = 0.002 Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 8/98 (8%) Query: 64 DTFFFVDS-IHYNGKGNDNG--RDDSSFYGEFSPRLSFGKIFQRDLSIGPITDVLVAMTY 120 D + ++D+ + + G G S + E PR S K+ DLS GP + A Y Sbjct: 71 DFYGYIDAPVFFGGNSTAKGIWNKGSPLFMEIEPRFSIDKLTNTDLSFGPFKEWYFANNY 130 Query: 121 EFGEGDVE-----TYMIGPGFDLNVPGFDYFSVNFYHR 153 + G + T+ +G G D++ S+N Y + Sbjct: 131 IYDMGRNDSQEQSTWYMGLGTDIDTGLPMSLSLNVYAK 168
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 34.2 bits (78), Expect = 4e-04 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 6/72 (8%) Query: 59 ITFEHASGWSWGDMFLFVDH-KWFNGHSG-----KDGRTYYGEFSPRLSLGKLTGTELSL 112 + +E + W D + ++D +F G+S G + E PR S+ KLT T+LS Sbjct: 59 LEYEAFAKKDWFDFYGYIDAPVFFGGNSTAKGIWNKGSPLFMEIEPRFSIDKLTNTDLSF 118 Query: 113 GPVNDVLISATY 124 GP + + Y Sbjct: 119 GPFKEWYFANNY 130
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.1 bits (65), Expect = 0.012 Identities = 21/115 (18%), Positives = 44/115 (38%), Gaps = 17/115 (14%) Query: 154 LYYDAAFDLIKAKDFDKASQAFAA--FLRKYPDSQYAGNAQYW--LGEVNLAKGDLQGAG 209 Y AF+ ++ ++ A + F A L Y +++++ LG A G A Sbjct: 38 QLYSLAFNQYQSGKYEDAHKVFQALCVLDHY-------DSRFFLGLGACRQAMGQYDLAI 90 Query: 210 QAFARVSQAYPQHNKVPDSLYKLADVEIRLGNRDKAQGIL---RQVIAQYPNTSA 261 +++ K P + A+ ++ G +A+ L +++IA Sbjct: 91 HSYSY---GAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEFKE 142
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.9 bits (67), Expect = 0.027 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 13/74 (17%) Query: 152 MAAMLAGVVAAAAGA-GDAGIAAIVSTQAAAIQAQRRFSRQN--EQEADRIG--IVNLER 206 +A++ +G+ AAA + A ++A+V I S+Q E A ++ I E+ Sbjct: 375 LASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEK 434 Query: 207 A--------GYDPR 212 GYD R Sbjct: 435 KHGKNYFENGYDAR 448
>PF01206#SirA family protein Length = 76 Score = 95.6 bits (238), Expect = 4e-30 Identities = 37/72 (51%), Positives = 52/72 (72%) Query: 12 DAEVDAVGLDCPMPLLKAKLELNRLASGAVLKVIASDPGSQRDFRSFAKLAGHALLREET 71 D +DA GL+CP+P+LKAK L + +G VL V+A+DPGS +DF SF+K GH LL ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 72 EDGVYRYWLRKA 83 EDG Y + L++A Sbjct: 65 EDGTYHFRLKRA 76
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.9 bits (168), Expect = 2e-16 Identities = 43/210 (20%), Positives = 70/210 (33%), Gaps = 14/210 (6%) Query: 9 PGPGRPKDPAKREAILAAAQVLFLGNGYEGSSMEAIAAEAGVSKLTLYSHFKDKEALFSA 68 + + R+ IL A LF G +S+ IA AGV++ +Y HFKDK LFS Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 69 AVKTTCETRLPRRLFQVEADCDIETVLLAIGGAFNELVNSPESIGLHRVMVAMATHNP-- 126 + L L + ++ S + R+++ + H Sbjct: 62 IWEL--SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 127 ----GLVKMFFDAGPQQLLCDLQQLFTTANTLG-LLEVDDPLRAAEHFCSLIKGAQHFRL 181 +V+ + ++Q L RAA I G L Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG-----L 174 Query: 182 LVGYAEAPTDEEGSLHVRDAVSVFLRAYRR 211 + + AP + RD V++ L Y Sbjct: 175 MENWLFAPQSFDLKKEARDYVAILLEMYLL 204
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 55.6 bits (134), Expect = 1e-10 Identities = 32/191 (16%), Positives = 72/191 (37%), Gaps = 17/191 (8%) Query: 93 DVRLQLDGMRAQVAAAEANLRVAKAEHDRYKALLGRQLVSQSQFDNADNAYRAAAARLQQ 152 + +L ++Q+ E+ + AK E+ L +++ + R + Sbjct: 263 EAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK---------LRQTTDNIGL 313 Query: 153 ARAEFDVASNQVDYAVLRATSDGLIAQRRI-EVGQVVAAGQTAFVLAADGER-EVAIDLP 210 E + +V+RA + Q ++ G VV +T V+ + + EV + Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQ 373 Query: 211 EQSLERYRVGQDVEVELWSQPGRHYL---GKIRELSPAADAQSRT---YSARVAFSEQEV 264 + + VGQ+ +++ + P Y GK++ ++ A R ++ ++ E + Sbjct: 374 NKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCL 433 Query: 265 PAELGQSALVS 275 L S Sbjct: 434 STGNKNIPLSS 444 Score = 46.4 bits (110), Expect = 1e-07 Identities = 27/153 (17%), Positives = 48/153 (31%), Gaps = 15/153 (9%) Query: 66 GGKVVERLVEAGDRVRKDQPLARLDPQDVRLQLDGMRAQVAAAEANLRVAKAEHDRYKAL 125 V E +V+ G+ VRK L +L A +++L A+ E RY+ L Sbjct: 104 NSIVKEIIVKEGESVRKGDVLLKLTALGA-------EADTLKTQSSLLQARLEQTRYQIL 156 Query: 126 LGRQLVSQSQFDNADNAYRAAAARLQQARAEFDVASNQVDYAVLRATSDGLIAQRRIEVG 185 + + Q E +V +T Q+ + + Sbjct: 157 S-----RSIELNKLPELKLPDEPYFQNVSEE-EVLRLTSLIKEQFSTWQNQKYQKELNLD 210 Query: 186 QVVAAGQTAFVLAADGEREVAIDLPEQSLERYR 218 + A T LA E + + L+ + Sbjct: 211 KKRAERLTV--LARINRYENLSRVEKSRLDDFS 241
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 474 bits (1221), Expect = e-153 Identities = 230/1045 (22%), Positives = 439/1045 (42%), Gaps = 55/1045 (5%) Query: 5 LSAWALQNRQIVVYLMLLLAIVGALSYSKLGQSEDPPFTFKAMVIQTQWPGATAEEMSRQ 64 ++ + ++ L ++L + GAL+ +L ++ P A+ + +PGA A+ + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 VTERIEKKLMETGEYERIVSFSRPGES---NVTFMARDSMRSKDIPDLWYQIRKKIGDIQ 121 VT+ IE+ + + S S S +TF D Q++ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQ-----SGTDPDIAQVQVQNKLQLAT 115 Query: 122 HTFPPGVRGP-FFNDEFGTTFGNIYALTGSGFDY--AILKDYADR-IQLQLQRVKSVGKV 177 P V+ ++ +++ + + DY ++ L R+ VG V Sbjct: 116 PLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDV 175 Query: 178 ELIGLQDEKIWIELSNVKLATLGVPLEAVRQALEAQNAVTAAGFVETISD------RVQL 231 +L G + I L L + V L+ QN AAG + + Sbjct: 176 QLFG-AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASI 234 Query: 232 RVTGSFETVKQIRDFPIRVA--GRTFRIGDVAEVHRGFNDPPAPRMRFMGEPALGLAVSM 289 F+ ++ +RV G R+ DVA V G + R G+PA GL + + Sbjct: 235 IAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNV-IARINGKPAAGLGIKL 293 Query: 290 KSGGDILVLGQALEQEFARLQQELPAGMQLRKVSDQPAAVKTGVGEFVKVLIEALVIVLL 349 +G + L +A++ + A LQ P GM++ D V+ + E VK L EA+++V L Sbjct: 294 ATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFL 353 Query: 350 VSFFSLG-VRTGLVVALSIPLVLAMTFAAMSYLDIGLHKISLGALVLALGLMVDDAIIAV 408 V + L +R L+ +++P+VL TFA ++ ++ +++ +VLA+GL+VDDAI+ V Sbjct: 354 VMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVV 413 Query: 409 EMMA-IKMEQGYDRLKAASFAWTSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQV 467 E + + ME +A + + ++ ++ +A F+P+A STG R Sbjct: 414 ENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSIT 473 Query: 468 VAISLIASWIAAVMFVPLIGEKLLPDLAKKTAHKHGTSSEGHDPYATPFYQRVRRLVTFC 527 + ++ S + A++ P + LL ++ + G + V Sbjct: 474 IVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 528 VRRRKTVILLTLAIFAAAVVLFRLVPQQFFPASGRLELMVDLKLAEGASLKATEAEVRRL 587 + +L+ I A VVLF +P F P + + ++L GA+ + T+ + ++ Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 588 EELL--KERAGIDNYVAYVGTGSPRFYLPLDQQLPATSFAQFVVLADSIE--SREALRSW 643 + E+A +++ G + FV L E E Sbjct: 594 TDYYLKNEKANVESVFTVNGFSFS--------GQAQNAGMAFVSLKPWEERNGDENSAEA 645 Query: 644 LIERMREDFPSLRGRVTRLENGPPV-------GYPVQ-FRVTGEHIDVVRGLARQVAAKV 695 +I R + + +R N P + G+ + G D + Q+ Sbjct: 646 VIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMA 705 Query: 696 NENP-HVANVHLDWQEPSKMVRLNVDQDRARALGVTTAELSGFLRRTFTGSSVSQFREDN 754 ++P + +V + E + +L VDQ++A+ALGV+ ++++ + G+ V+ F + Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 755 ELIEILLRGTERERLELSMLPSLAIPTESGRSVPLSQVATLEYGFEEGVIWHRNRLPTVT 814 + ++ ++ + R+ + L + + +G VP S T + + + N LP+ Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPS-- 823 Query: 815 VRADVYGEQQPAALVREIEPTLAEIRDQLPGGYLLEVGGTVEDSERGQRSVNAGMPLFVI 874 ++ GE P + + + +LP G + G A + + + Sbjct: 824 --MEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFV 881 Query: 875 VVLTLLMAQLKSFSRSAMVFLTAPLGIIGVALFLLLFGQPFGFVAMLGTIALSGMIMRNS 934 VV L A +S+S V L PLGI+GV L LF Q M+G + G+ +N+ Sbjct: 882 VVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNA 941 Query: 935 VILVDQIEQDIGA-GQARFSAIVEATVRRFRPIVLTALASVLAMIPLSRSIFFG-----P 988 +++V+ + + G+ A + A R RPI++T+LA +L ++PL+ S G Sbjct: 942 ILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNA 1001 Query: 989 MAVAIMGGLIVATALTLLFLPALYA 1013 + + +MGG++ AT L + F+P + Sbjct: 1002 VGIGVMGGMVSATLLAIFFVPVFFV 1026 Score = 72.2 bits (177), Expect = 8e-15 Identities = 79/522 (15%), Positives = 179/522 (34%), Gaps = 41/522 (7%) Query: 523 LVTFCVRRRKTVILLTLAIFAAAVVLFRLVPQQFFPASGRLELMVDLKLAEGASLKATEA 582 + F +RR +L + + A + +P +P + V GA + + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSAN-YPGADAQTVQD 59 Query: 583 EVRR-LEELLKERAGIDN---YVAYVGTGSPRFYLPLDQQLPATSFAQFVVLADSIESRE 638 V + +E+ + + G+ + AQ V + Sbjct: 60 TVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDP---DIAQVQV-------QN 109 Query: 639 ALRSWLIERMREDFPSLRGRVTRLENGPPVGYPVQFRVTG-EHIDVVRGLARQVAAKVNE 697 L+ + ++ V + + + G D+ +A V ++ Sbjct: 110 KLQL-ATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSR 168 Query: 698 NPHVANVHLDWQEPSKMVRLNVDQDRARALGVTTAELSGFLRRTFTGSSVSQF-----RE 752 V +V L + +R+ +D D +T ++ L+ + Q Sbjct: 169 LNGVGDVQLFGAQ--YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALP 226 Query: 753 DNEL-IEILLRGTERERLELSMLPSLAIPTESGRSVPLSQVATLEYGFEEGVIWHR-NRL 810 +L I+ + + E + G V L VA +E G E + R N Sbjct: 227 GQQLNASIIAQTRFKNPEEFGKVTLRV--NSDGSVVRLKDVARVELGGENYNVIARINGK 284 Query: 811 PTVTVRADVYGEQQPAALVREIEPTLAEIRDQLPGGYLLEVGGTVEDSERGQRSVNA--- 867 P + + + I+ LAE++ P G + + + Q S++ Sbjct: 285 PAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLY--PYDTTPFVQLSIHEVVK 342 Query: 868 -GMPLFVIVVLTLLMAQLKSFSRSAMVFLTAPLGIIGVALFLLLFGQPFGFVAMLGTIAL 926 ++V L + + L++ + + + P+ ++G L FG + M G + Sbjct: 343 TLFEAIMLVFLVMYLF-LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLA 401 Query: 927 SGMIMRNSVILVDQIEQ-DIGAGQARFSAIVEATVRRFRPIVLTALASVLAMIPL----- 980 G+++ +++++V+ +E+ + A ++ + +V A+ IP+ Sbjct: 402 IGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGG 461 Query: 981 SRSIFFGPMAVAIMGGLIVATALTLLFLPALYAAWFRVREDE 1022 S + ++ I+ + ++ + L+ PAL A + E Sbjct: 462 STGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAE 503
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 71.6 bits (175), Expect = 8e-18 Identities = 29/142 (20%), Positives = 50/142 (35%), Gaps = 3/142 (2%) Query: 2 ASNKRDQLLNTAEDLFYREGYHATGIDRILAESGVAKMTLYKHFKSKDELILAVLEARHE 61 A R +L+ A LF ++G +T + I +GV + +Y HFK K +L + E Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 62 LMLTRLRERASKMP--PREALLRVFD-GLHGMIHGGEQFCGCLFINAAAEYQDREHPIHQ 118 + E +K P P L + L + + I E+ + Q Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 119 RSAAYKGELQAYLRELLERMSA 140 E + + L+ Sbjct: 129 AQRNLCLESYDRIEQTLKHCIE 150
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.4 bits (63), Expect = 0.023 Identities = 12/49 (24%), Positives = 16/49 (32%), Gaps = 12/49 (24%) Query: 52 RGGWQELPPTQHIAVLIEHRGH---RLLFGTA---------LGRQIETQ 88 R W + IAV ++R L A G +ETQ Sbjct: 83 RSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQ 131
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.0 bits (65), Expect = 0.018 Identities = 22/85 (25%), Positives = 40/85 (47%), Gaps = 7/85 (8%) Query: 19 VKADNSGVDLANVKM---SMNPFCEIAVEEAVRLKEKGVASEIVVVSIGPTAAQEQLRTA 75 VKA+ G + + + + F + +EEA+ L+E+G I+++ G AQ+ Sbjct: 34 VKANAYGHGIERIWSAIGATDGFALLNLEEAITLRERGWKGPILMLE-GFFHAQD---LE 89 Query: 76 LALGADRAVLVESNDELNSLAVAKL 100 + V SN +L +L A+L Sbjct: 90 IYDQHRLTTCVHSNWQLKALQNARL 114
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.3 bits (63), Expect = 0.007 Identities = 16/102 (15%), Positives = 34/102 (33%), Gaps = 11/102 (10%) Query: 28 QLRLSEQAIEQARSVDASEAYEELILAESKLSAARAALEAGDNREARVL----------- 76 Q L + +EQ R S + E L E KL + R+ Sbjct: 140 QSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Query: 77 AEQAELDARLAEARVLKDKRQAQVDDLTRRIQRLRQQLGEVR 118 ++ + + L + R + A+++ + + +L + Sbjct: 200 NQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFS 241
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 90.4 bits (224), Expect = 3e-23 Identities = 40/113 (35%), Positives = 56/113 (49%), Gaps = 11/113 (9%) Query: 145 DLLFHAGSASLNSSANRTLLKLVHFL-QLNPQ-RKVRIEGYSDSRGDPQANLELSQARAQ 202 D+LF+ A+L L +L L L+P+ V + GY+D G N LS+ RAQ Sbjct: 220 DVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQ 279 Query: 203 TVADLLVSLGIAGERIEVRGYGERFPLAENASARGR---------AQNRRVEI 246 +V D L+S GI ++I RG GE P+ N + A +RRVEI Sbjct: 280 SVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEI 332
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 29.2 bits (65), Expect = 0.007 Identities = 18/76 (23%), Positives = 29/76 (38%) Query: 28 DVPAPSEPSAQAPVVSEPAEAPPDLQIELAAPEESADPALPDVQIKIPEPEPESAPRPVP 87 ++PAP++P + V E P +Q E P + P P+P P Sbjct: 37 ELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP 96 Query: 88 AKRPAPPKEEEVQLAE 103 +P P K+ + Q Sbjct: 97 KPKPKPVKKVQEQPKR 112
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 125 bits (316), Expect = 3e-37 Identities = 76/252 (30%), Positives = 114/252 (45%), Gaps = 8/252 (3%) Query: 7 GQVALVTGAAAGIGRATAQAFAEQGLKVVLADIDEAGIRDGAESIRAAGGEAIAVRCDVT 66 G++A +TGAA GIG A A+ A QG + D + + S++A A A DV Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 67 RDAEVKALIEQVLAQFGRLDYAFNNAGIEIEQGRLAEGSEAEFDAIMGVNVKGVWLCMKH 126 A + + ++ + G +D N AG+ + G + S+ E++A VN GV+ + Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 127 QLPVMLAQGGGAIVNTASVAGLGAAPKMSIYAASKHAVIGLTKSAAIEYAKKKIRVNAVC 186 M+ + G+IV S M+ YA+SK A + TK +E A+ IR N V Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 187 PAVIDTDMFRR----AYEADPRKAEFAAAMH---PVGRIGKVEEIAAAVLYLCCDGAAFT 239 P +TDM A+ P+ ++ K +IA AVL+L A Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 240 TGQALAVDGGAT 251 T L VDGGAT Sbjct: 247 TMHNLCVDGGAT 258
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 80.9 bits (199), Expect = 2e-23 Identities = 36/92 (39%), Positives = 52/92 (56%) Query: 18 QTDAMARAKPEVKTQEVGAPSFSDMLGQAVNKVHETQQVSSQISSAFEMGQGGVDLTEVM 77 Q A A + ++ SF+ L A++++ +TQ + + F +G+ GV L +VM Sbjct: 12 QLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVM 71 Query: 78 IASQKASVSFQAMTQVRNKLVQAYQDIMQMPV 109 QKASVS Q QVRNKLV AYQ++M M V Sbjct: 72 TDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 521 bits (1342), Expect = 0.0 Identities = 201/575 (34%), Positives = 304/575 (52%), Gaps = 38/575 (6%) Query: 27 LENLSDMSMLRQVGLLVGLAASVAIGFAVVLWSQQPDYRPLLGSLAGMDANQVMETLAAA 86 LE L+ + ++ L+V +A+VAI A+VLW++ PDYR L +L+ D ++ L Sbjct: 13 LEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQM 72 Query: 87 DIAYTVEPNSGALLVKANDLARARLKLASAGIAPADSNIGFEILDKDQGLGTSQFMEATR 146 +I Y SGA+ V A+ + RL+LA G+ P +GFE+LD+++ G SQF E Sbjct: 73 NIPYRFANGSGAIEVPADKVHELRLRLAQQGL-PKGGAVGFELLDQEK-FGISQFSEQVN 130 Query: 147 YRRGLEGELGRTISSLNNVKGARVHLAIPKSSVFVRDERKPSASVLVELYPGRALEPSQV 206 Y+R LEGEL RTI +L VK ARVHLA+PK S+FVR+++ PSASV V L PGRAL+ Q+ Sbjct: 131 YQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQI 190 Query: 207 MAIINLVATSVPELNKSQITVVDQKGNLLSDQQELTELSMAGKQFDYSRRMESLYTQRVH 266 A+++LV+++V L +T+VDQ G+LL+ Q + + Q ++ +ES +R+ Sbjct: 191 SAVVHLVSSAVAGLPPGNVTLVDQSGHLLT-QSNTSGRDLNDAQLKFANDVESRIQRRIE 249 Query: 267 NILQPVLGSGRYKAEVSADVDFSAVESTSETFNPDQPA----LRSEQSVNEQRQSSLPPQ 322 IL P++G+G A+V+A +DF+ E T E ++P+ A LRS Q ++ + P Sbjct: 250 AILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPG 309 Query: 323 GVPGALSNQPPGPAAAPEQANQAAAAAGAVAPGQPLLDANGQQIMDPATGQPMLAPFPAD 382 GVPGALSNQP P AP P N Q +T + P Sbjct: 310 GVPGALSNQPAPPNEAPIAT-------------PPTNQQNAQNTPQTSTSTNSNSAGPRS 356 Query: 383 KREQATRNYELDRSISYTKQQHGRLRRLSVAVVVDDQMTLNAAGEMVRVPWTADDLARFT 442 + T NYE+DR+I +TK G + RLSVAVVV+ + + P TAD + + Sbjct: 357 TQRNETSNYEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPL----PLTADQMKQIE 412 Query: 443 RLVQDSVGFDASRGDSVSVINTAFVADSFGETFEEIPFYSQPWFWDVVKQVLGVLFILVL 502 L ++++GF RGD+++V+N+ F A T E+PF+ Q F D + L +LV+ Sbjct: 413 DLTREAMGFSDKRGDTLNVVNSPFSAVD--NTGGELPFWQQQSFIDQLLAAGRWLLVLVV 470 Query: 503 VF----GVLRPVLKSLTNPSSGKELQVANGPGDLGDEEGLESGLSNDRVSLSGPQNILLP 558 + +RP L + + Q EE +E LS D N L Sbjct: 471 AWILWRKAVRPQLTRRVEEAKAAQEQAQVR---QETEEAVEVRLSKDEQLQQRRANQRL- 526 Query: 559 SPSEGYEAQLNAIKNLVADDPGRVAQVVKEWINAD 593 G E I+ + +DP VA V+++W++ D Sbjct: 527 ----GAEVMSQRIREMSDNDPRVVALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 302 bits (775), Expect = e-104 Identities = 105/330 (31%), Positives = 199/330 (60%) Query: 9 KLNKVDKAAILLLSLGETDAAQVLRHLGPKEVQRVGTAMAQMRNVQKTQIEQVMSEFVEI 68 L KAAILL+S+G +++V ++L +E++ + +A++ + + V+ EF E+ Sbjct: 14 ALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFKEL 73 Query: 69 VGDQTSLGVGSDGYIRKMLTQALGEDKAGGLIDRILLGGNTSGLDSLKWMEPRAVADVIR 128 + Q + G Y R++L ++LG KA +I+ + + + ++ +P + + I+ Sbjct: 74 MMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILNFIQ 133 Query: 129 YEHPQIQAIVVAYLDPDQAGEVLSHFDHKVRLDIVLRVSSLNTVQPAALKELNLILEKQF 188 EHPQ A++++YLDP +A +LS +V+ ++ R++ ++ P ++E+ +LEK+ Sbjct: 134 QEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEKKL 193 Query: 189 SGSTNTSRASLGGVKRAADIMNYLDSSIEGQLMDAIRDVDEDLSSQIEDLMFVFDNLAEV 248 + ++ S GGV +I+N D E +++++ + D +L+ +I+ MFVF+++ + Sbjct: 194 ASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDIVLL 253 Query: 249 DDRGIQVLLREVSSDVLVMALKGADDGIKEKVFKNMSKRAGELLRDDLEAKGPVRVSDVE 308 DDR IQ +LRE+ L ALK D ++EK+FKNMSKRA +L++D+E GP R DVE Sbjct: 254 DDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRKDVE 313 Query: 309 NAQKEILTIARRMAEAGEIVLGSKGGEEMI 338 +Q++I+++ R++ E GEIV+ G E+++ Sbjct: 314 ESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 55.6 bits (133), Expect = 2e-11 Identities = 46/197 (23%), Positives = 92/197 (46%), Gaps = 21/197 (10%) Query: 44 PVEELARSEDVPVEEVKPLTLDELEAIRQQAYNEGFATGEKDGFHAGQLKARQE------ 97 P+ E E+ +EE +P +L ++ QA+ +G+ G +G G + QE Sbjct: 24 PIVE---PEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEGLAQGL 80 Query: 98 ------ADAALAPRVESLERLMGQLLDPIADQDRNLEHAMATLVSHMAREVIQRDLLIDS 151 A + AP +++L+ + + D + + + AR+VI + +D+ Sbjct: 81 EQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDN 140 Query: 152 SQIRQVLREALKLLPMGASNVRIHVNPQDF----ELIKALRERHEESWRILEDSSLLPGG 207 S + + +++ L+ P+ + ++ V+P D +++ A H WR+ D +L PGG Sbjct: 141 SALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLH--GWRLRGDPTLHPGG 198 Query: 208 CHIETEHSRIDASIETR 224 C + + +DAS+ TR Sbjct: 199 CKVSADEGDLDASVATR 215
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 58.3 bits (140), Expect = 1e-13 Identities = 48/138 (34%), Positives = 74/138 (53%) Query: 9 LAPVIEMAERAERDAARLLGQAQTQLAQAETKLAELDQYFRDYQQQWMQQGSQGVSGQWL 68 LA + ++AE+ DAARLLG+ + QAE +L L Y +Y+ S G++ Sbjct: 7 LATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAGITSNRW 66 Query: 69 MNYQRFLSQLESAIGQQQRSVNWYRDNLLKVRQQWHQKHARLEGLSKLIESYQREARIAA 128 +NYQ+F+ LE AI Q ++ +N + + W +K RL+ L E A +A Sbjct: 67 INYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQSTAALLAE 126 Query: 129 DKREQKLLDEFAQRLAGR 146 ++ +QK +DEFAQR A R Sbjct: 127 NRLDQKKMDEFAQRAAMR 144
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.4 bits (201), Expect = 2e-18 Identities = 30/166 (18%), Positives = 71/166 (42%), Gaps = 7/166 (4%) Query: 2 RLSILIAEDSPVDRMLLSTIVTRQGHRVLTAADGQEAVELFQQERPQLVLMDALMPVMDG 61 +IL+A+D R +L+ ++R G+ V ++ LV+ D +MP + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 FEAARRIKQLAGDELVPIIFLTSLTENEALVQCLEAGGDDFIAKPYNPI-ILEAKIQAMH 120 F+ RIK+ +P++ +++ ++ E G D++ KP++ ++ +A+ Sbjct: 63 FDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 RLRRLQATVLEQRDLIARRNQQLLAEHRAAKAIFDKVAHAGCLSAP 166 +R + + + ++ L+ A + I+ +A Sbjct: 121 EPKRRPSKLEDD----SQDGMPLVGRSAAMQEIYRVLARLMQTDLT 162
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 57.2 bits (137), Expect = 4e-11 Identities = 40/138 (28%), Positives = 68/138 (49%), Gaps = 2/138 (1%) Query: 276 WSEAVVDRVMWLSSQNLKSAEIQLDPAELGRMEVRIDLTKDQAQVTFLSPHAGVRDALEG 335 W +++ + + Q +SAE++L P +LG +++ + + +QAQ+ +SPH VR ALE Sbjct: 240 WQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEA 299 Query: 336 QMQRLREMFTQQGMNLMDVNVSDQSLARGWQGGTDGGGSSRGGSSAEGEADDGEVQLGVS 395 + LR + G+ L N+S +S + Q + S R + +D + L V Sbjct: 300 ALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGED-DDTLPVP 358 Query: 396 EIAGNRSAGNRGLVDFYA 413 R GN G VD +A Sbjct: 359 VSLQGRVTGNSG-VDIFA 375
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 259 bits (662), Expect = 5e-87 Identities = 99/323 (30%), Positives = 169/323 (52%), Gaps = 9/323 (2%) Query: 5 DLLSQDEIDALLHGVDDG---LVDTESDSEPGSIKSYDLTSQDRIVRGRMPTLEMINERF 61 ++LSQDEID LL + G + D S+ I YD D+ + +M TL +++E F Sbjct: 3 EVLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETF 62 Query: 62 ARYTRISMFNLLRRSADVSVGGVQVMKFGEYVHSLYVPTSLNLVKMKPLRGTALFILDAK 121 AR T S+ LR V V V + + E++ S+ P++L ++ M PL+G A+ +D Sbjct: 63 ARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPS 122 Query: 122 LVFKLVDNFFGGDGRHAKIEGREFTPTELRVVRMVLDQAFADLKEAWHAVLDVNFEYVNS 181 + F ++D FGG G+ AK++ R+ T E V+ V+ + A+++E+W V+D+ Sbjct: 123 ITFSIIDRLFGGTGQAAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQI 181 Query: 182 EVNPALANIVSPSEVVVVSTFHIELDSGGGDLHVTMPYSMIEPIREMLDAGF--QSDVSD 239 E NP A IV PSE+VV+ T ++ G ++ +PY IEPI L + F S Sbjct: 182 ETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRRS 241 Query: 240 QDERWVKALREDILDVNVPLGATVVRRQLKLRDILNMQPGDVIPVE---MPEDMIMRANG 296 +++ LR+ + V++ + A V +L +RDIL ++ GD+I + + + ++ Sbjct: 242 STTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIGN 301 Query: 297 MPAFKVKLGAHKGNLALQVLEPV 319 F + G +A Q+LE + Sbjct: 302 RKKFLCQPGVVGKKIAAQILERI 324
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 121 bits (306), Expect = 2e-38 Identities = 63/157 (40%), Positives = 94/157 (59%), Gaps = 23/157 (14%) Query: 1 MADERDNTSPEEQALADEWAAALAE-AGDASQDDIDALLNQAPAAAAPAAPRAPLEDFAS 59 M+D + + AL D WA AL E ++ DA+ Q A + Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQ-------- 52 Query: 60 APKSTAVPLGLEGPNLDVILDIPVSISMEVGSTEISIRNLLQLNQGSVVELDRLAGEPLD 119 ++D+I+DIPV +++E+G T ++I+ LL+L QGSVV LD LAGEPLD Sbjct: 53 --------------DIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLD 98 Query: 120 VLVNGTLIAHGEVVVVNEKFGIRLTDVISPTERIKKL 156 +L+NG LIA GEVVVV +K+G+R+TD+I+P+ER+++L Sbjct: 99 ILINGYLIAQGEVVVVADKYGVRITDIITPSERMRRL 135
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 265 bits (680), Expect = 4e-92 Identities = 146/257 (56%), Positives = 183/257 (71%), Gaps = 16/257 (6%) Query: 1 MLRILLVA--VLMLCGPLAMAQEPSGILAQGNNPLSIPAITLTTDAEGQQEYSVSLQILL 58 M R+L VA +L L PLA AQ +P IT G Q +S+ +Q L+ Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQ--------------LPGITSQPLPGGGQSWSLPVQTLV 46 Query: 59 IMTALSFIPAFVMLMTSFTRIIIVFSILRQALGLQQTPSNQILIGLTLFLTLFIMAPVFD 118 +T+L+FIPA +++MTSFTRIIIVF +LR ALG P NQ+L+GL LFLT FIM+PV D Sbjct: 47 FITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVID 106 Query: 119 RINQDALQPYLSEQIPAQEAISRAEVPLKNFMLAQTRESDLELFVRLSRRTDIASPEAAP 178 +I DA QP+ E+I QEA+ + PL+ FML QTRE+DL LF RL+ + PEA P Sbjct: 107 KIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVP 166 Query: 179 MTILVPAFVTSELKTAFQIGFMIFIPFLIIDMVVASVLMAMGMMMLSPLIISLPFKIMLF 238 M IL+PA+VTSELKTAFQIGF IFIPFLIID+V+ASVLMA+GMMM+ P I+LPFK+MLF Sbjct: 167 MRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLF 226 Query: 239 VLVDGWGLIIGTLAGSF 255 VLVDGW L++G+LA SF Sbjct: 227 VLVDGWQLLVGSLAQSF 243
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 56.3 bits (136), Expect = 2e-14 Identities = 22/75 (29%), Positives = 40/75 (53%) Query: 7 VDLFREGLWMTAMIVGVLVVPSLLVGLVVAMFQAATQINEQTLSFLPRLLVMLLTLIWAG 66 V + L++ ++ G + + ++GL+V +FQ TQ+ EQTL F +LL + L L Sbjct: 5 VFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLLS 64 Query: 67 PWLVRELMEYTQNLV 81 W L+ Y + ++ Sbjct: 65 GWYGEVLLSYGRQVI 79
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 131 bits (330), Expect = 4e-39 Identities = 102/255 (40%), Positives = 158/255 (61%), Gaps = 2/255 (0%) Query: 1 MLELSNAQIGGWVGQFLLPLFRIAALLMSMPIIGTQLVPVRVRLYLALAIALVLVPTLPP 60 ML++++ Q W+ + PL R+ AL+ + PI+ + VP RV+L LA+ I + P+LP Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 MPVVESLSLASLLLIAEQLLIGVMLGFVLQLFFHVFIVSGQMLAMQMGLGFASMVDPANG 120 V S +L L +Q+LIG+ LGF +Q F +G+++ +QMGL FA+ VDPA+ Sbjct: 61 NDVPV-FSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASH 119 Query: 121 ISVPVLGQFFNMLVILLFLSVNGHLVVLEILAESFVTLPVGGGLSTNHFWEVAGKLGW-V 179 +++PVL + +ML +LLFL+ NGHL ++ +L ++F TLP+GG ++ + K G + Sbjct: 120 LNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLI 179 Query: 180 LGAGLLLVLPAITALLVVNLAFGLMTRAAPQLNIFSIGFPLTLVLGLIIVWIGMADIFAQ 239 GL+L LP IT LL +NLA GL+ R APQL+IF IGFPLTL +G+ ++ M I Sbjct: 180 FLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPF 239 Query: 240 YQIFVSEALLMLREL 254 + SE +L ++ Sbjct: 240 CEHLFSEIFNLLADI 254
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 328 bits (842), Expect = e-113 Identities = 101/349 (28%), Positives = 180/349 (51%), Gaps = 2/349 (0%) Query: 8 ADKSEEPTEKRLRESREKGQLARSRELSTVAVTLGGIGGLLASGGSLAQTLMAMMQGTFE 67 +K+E+PT K++R++R+KGQ+A+S+E+ + A+ + L+ + +M E Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAE 62 Query: 68 LSRETLLDEGSMVRLLMGSGLMALEAIMPLLIALLIASIVGPVSLGGWLFSAKAMAPKVS 127 S ++ ++ L PLL + +I V G+L S +A+ P + Sbjct: 63 QSYLPF--SQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIK 120 Query: 128 RMNPAAGLKRMFSTKALVELLKALGKFLVVLGVALLVLSAYQDDLLSIAKQPLDLAIMHS 187 ++NP G KR+FS K+LVE LK++ K +++ + +++ LL + ++ Sbjct: 121 KINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLL 180 Query: 188 AEIVGWCALWMACGLIVIAAVDVPFQLWDNKQKLMMTKQEVKDEYKDSEGKPEVKSRIRQ 247 +I+ + G +VI+ D F+ + ++L M+K E+K EYK+ EG PE+KS+ RQ Sbjct: 181 GQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQ 240 Query: 248 LQREAAQRRMMQAVPEADVVITNPTHFAVALKYDGDKGGAPRLVAKGGDFVALKIREIAQ 307 +E R M + V + VV+ NPTH A+ + Y + P + K D +R+IA+ Sbjct: 241 FHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAE 300 Query: 308 EHKVTVLESPALARAVYYSTELDQEIPAGLYLAVAQVLAYVYQLRQYRA 356 E V +L+ LARA+Y+ +D IPA A A+VL ++ + + Sbjct: 301 EEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEKQ 349
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.030 Identities = 7/24 (29%), Positives = 11/24 (45%) Query: 210 GVIALVGPAGVGKTTTLAKLAARY 233 + L G G+GK+T + L Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGLD 620
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.0 bits (231), Expect = 2e-25 Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 3/120 (2%) Query: 6 KILIVDDFSTMRRIIKNLLRDLGFTNTAEADDGTTALPMLKSGSFDFLVTDWNMPGMSGI 65 IL+ DD + +R ++ L G+ + T + +G D +VTD MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 DLLRTVRADERLKHLPVLMVTAEAKRDQIIEAAQAGVNGYVVKPFTAQVLKEKIEKIFER 125 DLL ++ + LPVL+++A+ I+A++ G Y+ KPF L I + Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>PF06580#Sensor histidine kinase Length = 349 Score = 42.9 bits (101), Expect = 3e-06 Identities = 14/73 (19%), Positives = 31/73 (42%), Gaps = 10/73 (13%) Query: 432 ETDLDKNLVEALADPLV--HLVRNAVDHGIEMPEEREAAGKPRTGRVVLSAEQEGDHILL 489 E ++ +++ P++ LV N + HGI P+ G+++L ++ + L Sbjct: 243 ENQINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTL 294 Query: 490 IISDDGKGMDANV 502 + + G N Sbjct: 295 EVENTGSLALKNT 307
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.1 bits (143), Expect = 1e-11 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 5/109 (4%) Query: 2 AVKVLVVDDSGFFRRRVSEILSSDSNIQVVGTATNGREAIDQVLALKPDVITMDYEMPMM 61 +LV DD R +++ LS + V +N + A D++ D MP Sbjct: 3 GATILVADDDAAIRTVLNQALS-RAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGITAVRQIMQRCP-TPVLMFSSLTHEGARVTLDALDAGAVDYLPKNFE 109 + + +I + P PVL+ S+ + A + GA DYLPK F+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAI--KASEKGAYDYLPKPFD 107
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 77.7 bits (191), Expect = 1e-18 Identities = 39/128 (30%), Positives = 58/128 (45%), Gaps = 16/128 (12%) Query: 134 LNSSLLFPSGDALPNDHAFALIEKVAGILA---PFDNPIHVEGFTDNLPISTDKFPTNWE 190 L S +LF A A ++++ L+ P D + V G+TD I +D + N Sbjct: 217 LKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR--IGSDAY--NQG 272 Query: 191 LSAARAGSVVRMLAAQGVDPSRLAAVGYGEFQPVADNATAAGRAR---------NRRVIL 241 LS RA SVV L ++G+ +++A G GE PV N + R +RRV + Sbjct: 273 LSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEI 332 Query: 242 VVSRNLDV 249 V DV Sbjct: 333 EVKGIKDV 340
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 28.4 bits (63), Expect = 0.028 Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 4/65 (6%) Query: 52 RQSQPPRLEIVQPAAPVPPAVVVPEVMLPSTPSVEPVVRVEVVPQTPAAPVEVVADGQPA 111 +QP + +V PA PP V P P P VEP E +P+ P V+ +P Sbjct: 45 APAQPISVTMVAPADLEPPQAVQP----PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPK 100 Query: 112 WAEEP 116 +P Sbjct: 101 PKPKP 105 Score = 27.6 bits (61), Expect = 0.041 Identities = 14/71 (19%), Positives = 19/71 (26%), Gaps = 7/71 (9%) Query: 55 QPPRLEIVQPAAPV----PPAVVVPEVMLPSTPSVEPVVRVEVVPQTPAAPVEVV---AD 107 P + P PV P +PE + +E P VE Sbjct: 60 LEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVK 119 Query: 108 GQPAWAEEPFE 118 + PFE Sbjct: 120 PVESRPASPFE 130
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.8 bits (93), Expect = 2e-05 Identities = 30/198 (15%), Positives = 62/198 (31%), Gaps = 54/198 (27%) Query: 8 PARFSPRWLLLILAVAAIGLLVWWLWPAPQETPQRPGGRPGFGAFGGPVPVRVAKVEQGE 67 P PR + + + + + G V + Sbjct: 52 PVSRRPRLVAYFIMGFLVIAFIL--------------------SVLGQVEIVAT------ 85 Query: 68 FEVFNKALGSVTPL-NTVNLRSRVGGELVELRFEEGQRVKKGDLLAVIDPRPYKVALQQA 126 A G +T + ++ + E+ +EG+ V+KGD+L + A Sbjct: 86 ------ANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTAL-------GA 132 Query: 127 EGTLQQNRAQLKNAQVDFERYRGL-------------FADDSIAKQTLDTQE-ALVSQYQ 172 E + ++ L A+++ RY+ L D+ + + + L S + Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 173 GTLAANQASVNEARLNLE 190 + Q + LNL+ Sbjct: 193 EQFSTWQNQKYQKELNLD 210 Score = 36.7 bits (85), Expect = 1e-04 Identities = 17/146 (11%), Positives = 38/146 (26%), Gaps = 46/146 (31%) Query: 123 LQQAEGTLQQNRAQLKNAQVDFERYRGLFADDSIAKQTLDTQEALVSQYQGTLAANQASV 182 + + + + + + L +IAK + QE + L ++ + Sbjct: 216 RLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQL 275 Query: 183 NE-------------------------------------------ARLNLEFTQIRSPID 199 + + + IR+P+ Sbjct: 276 EQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVS 335 Query: 200 GRV-GLRQLDVGNLVAANDTTPLVVI 224 +V L+ G +V L+VI Sbjct: 336 VKVQQLKVHTEGGVVTT--AETLMVI 359
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 841 bits (2173), Expect = 0.0 Identities = 296/1037 (28%), Positives = 519/1037 (50%), Gaps = 35/1037 (3%) Query: 3 ISRLFILRPVATTLSMVAILLAGLIAYKLLPVAALPQVDYPTIRVMTLYPGASPEVMTSA 62 ++ FI RP+ + + +++AG +A LPVA P + P + V YPGA + + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VTAPLERQFGQMPGLAQMSSTS-SGGASVITLRFSLDVALDVAEQEVQAAINGANNLLPN 121 VT +E+ + L MSSTS S G+ ITL F D+A+ +VQ + A LLP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 DLPAPPVYNKVNPADTPVLTLAVTSESLPLPK--LHDLVDTRMAQKLAQINGVGMVSIAG 179 ++ + + + ++ S++ + + D V + + L+++NGVG V + G Sbjct: 121 EVQQQGIS-VEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 180 GQRPAVRIRTNPEALAAYGLSLADVRSLITSSNVNQPKGNFDGPTRVS------MLDAND 233 Q A+RI + + L Y L+ DV + + N G G + + A Sbjct: 180 AQY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 234 QLKTPEEYAELIL-TYQDGAALRLKDVADIVDGAENERLAAWANESQAVLLNVQRQPGAN 292 + K PEE+ ++ L DG+ +RLKDVA + G EN + A N A L ++ GAN Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 293 VIDVVERIQALLPEVTASMPAGLDVVVLTDRTQTIRAAVTDVQHELMLATFLVVMVTFVF 352 +D + I+A L E+ P G+ V+ D T ++ ++ +V L A LV +V ++F Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 353 LKKLSATVIPSIAVPLSLVGTFAVMYVCGFSLNNLTLMALTIATGFVVDDAIVMLENIAR 412 L+ + AT+IP+IAVP+ L+GTFA++ G+S+N LT+ + +A G +VDDAIV++EN+ R Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 413 HL-EEGETPLNAALKGARQIGFTLISLTFSLIAVLIPLLFMQDVVGRLFREFAITLAVAI 471 + E+ P A K QI L+ + L AV IP+ F G ++R+F+IT+ A+ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 472 LISLVVSLTLTPMMCAKLLKPHSVAEAKP-----DWVER----LIGGYSRWLTWVLRHQT 522 +S++V+L LTP +CA LLKP S + W + Y+ + +L Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 523 LTLLVAVATLGLTVVLYLAVPKGFFPVQDTGVIQGISEAPQSISFRAMSERQQALARVIL 582 LL+ + VVL+L +P F P +D GV + + P + + + L Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 583 ADPS--VQSLSSYIGVDGDNVTLNSGRLLINLKPHGERD---LTASQIIDRLRPELAKVP 637 + V+S+ + G N+G ++LKP ER+ +A +I R + EL K+ Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 638 GIELYLQPVQDLSIEDRVSRTQFQFSLET---PDSELLQEWTPRLVEALRERP-ELTDVA 693 + ++ P +I + + T F F L + L + +L+ + P L V Sbjct: 659 --DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVR 716 Query: 694 SDLQSNGLQIYLDIDRDAAARLGIQVADITDALYDAFGQRQISTIFTQASQYRVVLEAEA 753 + + Q L++D++ A LG+ ++DI + A G ++ + ++ ++A+A Sbjct: 717 PNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADA 776 Query: 754 GNRLGPQALEQLFVQSEGGTPVRLSSLATFEQRNAPLLINHIGQFPAVTLSFNLASGVSL 813 R+ P+ +++L+V+S G V S+ T + P++ + A G S Sbjct: 777 KFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSS 836 Query: 814 GKAVEVIEAVEQQIGLPAGIQTRFQGAAEAFRASLSSTLLLIFAAVVTMYIVLGVLYESY 873 G A+ ++E + + LPAGI + G + R S + L+ + V +++ L LYES+ Sbjct: 837 GDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESW 894 Query: 874 IHPITILSTLPSAAVGALLALLLTGNDLGLIAIIGIILLIGIVKKNAIMMIDFALEAERH 933 P++++ +P VG LLA L + ++G++ IG+ KNAI++++FA + Sbjct: 895 SIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEK 954 Query: 934 QGMSPQDAIYRAALLRFRPILMTTLAALFGAIPLMLASGSGAELRQPLGLVLVGGLLLSQ 993 +G +A A +R RPILMT+LA + G +PL +++G+G+ + +G+ ++GG++ + Sbjct: 955 EGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSAT 1014 Query: 994 LLTLFTTPVIYLFFDRL 1010 LL +F PV ++ R Sbjct: 1015 LLAIFFVPVFFVVIRRC 1031 Score = 85.7 bits (212), Expect = 5e-19 Identities = 72/508 (14%), Positives = 166/508 (32%), Gaps = 35/508 (6%) Query: 2 NISRLFILRPVATTLSMVAILLAGLIAYKLLPVAALPQVDYPTIRV-MTLYPGASPEVMT 60 N + L I+ ++ + LP + LP+ D + L GA+ E Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 61 SAVT----------APLERQFGQMPGLAQMSSTSSGGASVITL-------RFSLDVALDV 103 + + G + + G + ++L + Sbjct: 588 KVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVI 647 Query: 104 AEQEVQ-AAINGANNLLPNDLPAPPVYNKVNPADTPVLTLAVTSESLPLPKLHDLVDTRM 162 +++ I + N + + + ++ L + + + Sbjct: 648 HRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDA--LTQARNQLLGMA 705 Query: 163 AQKLAQINGVGMVSIAGGQRPAVRIRTNPEALAAYGLSLADVRSLITSSNVNQPKGNFDG 222 AQ A + V + ++ + E A G+SL+D+ I+++ +F Sbjct: 706 AQHPASLVSVRPNGLEDT--AQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFID 763 Query: 223 PTR----VSMLDANDQLKTPEEYAELILTYQDGAALRLKDVADIVDGAENERLAAWANES 278 R DA PE+ +L + +G + + RL N Sbjct: 764 RGRVKKLYVQADA-KFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLER-YNGL 821 Query: 279 QAVLLNVQRQPGANVIDVVERIQALLPEVTASMPAGLDVVVLTDRTQTIRAAVTDVQHEL 338 ++ + + PG + D + ++ L + +PAG+ T + R + + Sbjct: 822 PSMEIQGEAAPGTSSGDAMALMENLASK----LPAGIGYDW-TGMSYQERLSGNQAPALV 876 Query: 339 MLATFLVVMVTFVFLKKLSATVIPSIAVPLSLVGTFAVMYVCGFSLNNLTLMALTIATGF 398 ++ +V + + S V + VPL +VG + + ++ L G Sbjct: 877 AISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGL 936 Query: 399 VVDDAIVMLENI-ARHLEEGETPLNAALKGARQIGFTLISLTFSLIAVLIPLLFMQDVVG 457 +AI+++E +EG+ + A L R ++ + + I ++PL Sbjct: 937 SAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGS 996 Query: 458 RLFREFAITLAVAILISLVVSLTLTPMM 485 I + ++ + ++++ P+ Sbjct: 997 GAQNAVGIGVMGGMVSATLLAIFFVPVF 1024
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 795 bits (2054), Expect = 0.0 Identities = 273/1031 (26%), Positives = 502/1031 (48%), Gaps = 27/1031 (2%) Query: 7 FIARPVATMLLSLAILLLGGVSFGLLPVSPLPNMDFPVITVQASLPGASPEIMASSVATP 66 FI RP+ +L++ +++ G ++ LPV+ P + P ++V A+ PGA + + +V Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 67 LERSLGSIAGVSQMTSRS-SQGSTRIIIQFDLDRDINGAARDVQAAINASRNLLPSGMRS 125 +E+++ I + M+S S S GS I + F D + A VQ + + LLP ++ Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 126 MPTYRKINPSQAPIMVLSLTSE--VLDKAELYDIGSTILAQKLSQVSGVGEIQVGGSSLP 183 + S + +MV S+ + ++ D ++ + LS+++GVG++Q+ G+ Sbjct: 125 QGISVE-KSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY- 182 Query: 184 AVRVELQPQQLEQYGVSLDEVRQTIANGNVRRPKG------MVEDADQHWQVRANDQLHQ 237 A+R+ L L +Y ++ +V + N + G + + + A + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 238 AADYTPLIIRY-QDGAALRLGDVARVRDSVEDRYNSGFFNNEQAVLLIVNRQAGANIIET 296 ++ + +R DG+ +RL DVARV E+ N + A L + GAN ++T Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 297 IEGIRRELPALQAIMPGSVDLNIAMDRSPVIRATLHEAERTLLIAVGLVIVLVFLFLGRL 356 + I+ +L LQ P + + D +P ++ ++HE +TL A+ LV ++++LFL + Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 357 RTALIPALAVPVSLVGTFAVMYMFGFSLNVLSLMALILAAGLVVDDAIVVLENIARHI-D 415 R LIP +AVPV L+GTFA++ FG+S+N L++ ++LA GL+VDDAIVV+EN+ R + + Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 416 DGMPPLKAAYVGTREVGFTLLSMNLSLVVVFVSILYMGGIVERLFREFSITLAAAILVSL 475 D +PP +A ++ L+ + + L VF+ + + GG ++R+FSIT+ +A+ +S+ Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 476 LVSLTLTPMLCARWLKP---HEPEKEGRLQRWSHDAHQWLLRYYDRSLSWALRHRRITLL 532 LV+L LTP LCA LKP E +G W + + +Y S+ L LL Sbjct: 483 LVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLL 542 Query: 533 SLLATIALNVVLYVQVPKTFLPQQDTGQITGFIRGDDGMSFQVMQPKMEIFRKAVLADPA 592 +A VVL++++P +FLP++D G I+ G + + Q ++ L + Sbjct: 543 IYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEK 602 Query: 593 VE-----SVAGFIGGQGGINNAFMIVRLKPLNER---GISAQKVIERIRKNQPKVPGGRM 644 +V GF N V LKP ER SA+ VI R + K+ G + Sbjct: 603 ANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFV 662 Query: 645 FLMADQDLQFGGGRQSSSAYAYTLLASDLNDLRTWVPQV-TRALSDLPELTSIDANDGEG 703 + G + L Q+ A L S+ N E Sbjct: 663 IPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLED 722 Query: 704 AQQISLKIDRDAAKRLGIDMSTVTTLLNNAFSQRQISTIYESLNQYQVVMEIDPSYAQYP 763 Q L++D++ A+ LG+ +S + ++ A ++ + ++ ++ D + P Sbjct: 723 TAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLP 782 Query: 764 EVLEQIHVVTSDGRRVPLAAFARYERSLEEDRVSHDGQFAAENIDFDLAPGVSLDQATLA 823 E +++++V +++G VP +AF R+ + I + APG S A Sbjct: 783 EDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMAL 842 Query: 824 IERAVAAIGMPSEVQGRLGGTGSAFQTTQEGQPLMILGALLLVYIVLGILYESYIHPLTI 883 +E + +P+ + G + + P ++ + ++V++ L LYES+ P+++ Sbjct: 843 MENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 884 LSTLPSAGVGALLAIILTGDQFSLISLLGLFLLIGVVKKNAILMIDLALQFERQDKLSPA 943 + +P VG LLA L + + ++GL IG+ KNAIL+++ A ++ Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 944 DSIHRACLLRFRPILMTTMAAILGALPLLLGGAEGAEMRQPLGLTIIGGLLLSQILTLYT 1003 ++ A +R RPILMT++A ILG LPL + G+ + +G+ ++GG++ + +L ++ Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1004 TPVVYLYLDRL 1014 PV ++ + R Sbjct: 1021 VPVFFVVIRRC 1031 Score = 83.3 bits (206), Expect = 3e-18 Identities = 75/412 (18%), Positives = 151/412 (36%), Gaps = 22/412 (5%) Query: 623 ISAQKVIERIRKNQPKVPGG----RMFLMADQDLQFGGGRQSSSAYAYTLLASDLNDLRT 678 I+ +V +++ P +P + + S T D++D Sbjct: 102 IAQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQ--DDISDYVA 159 Query: 679 WVPQVTRALSDLPELTSIDANDGEGAQQISLKIDRDAAKRLGIDMSTVTTLLNNAFSQ-- 736 V LS L + + + A +I L D D + + V L Q Sbjct: 160 SN--VKDTLSRLNGVGDVQLFGAQYAMRIWL--DADLLNKYKLTPVDVINQLKVQNDQIA 215 Query: 737 --RQISTIYESLNQYQVVMEIDPSYAQYPEVLEQIHV-VTSDGRRVPLAAFARYERSLEE 793 + T Q + + + PE ++ + V SDG V L AR E E Sbjct: 216 AGQLGGTPALPGQQLNASIIAQ-TRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGEN 274 Query: 794 DR--VSHDGQFAAENIDFDLAPGVSLDQATLAIERAVAAI--GMPSEVQ-GRLGGTGSAF 848 +G+ AA LA G + AI+ +A + P ++ T Sbjct: 275 YNVIARINGKPAAGLGIK-LATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFV 333 Query: 849 QTTQEGQPLMILGALLLVYIVLGILYESYIHPLTILSTLPSAGVGALLAIILTGDQFSLI 908 Q + + A++LV++V+ + ++ L +P +G + G + + Sbjct: 334 QLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTL 393 Query: 909 SLLGLFLLIGVVKKNAILMIDLALQFERQDKLSPADSIHRACLLRFRPILMTTMAAILGA 968 ++ G+ L IG++ +AI++++ + +DKL P ++ ++ ++ M Sbjct: 394 TMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVF 453 Query: 969 LPLLLGGAEGAEMRQPLGLTIIGGLLLSQILTLYTTPVVYLYLDRLRHRFNS 1020 +P+ G + + +TI+ + LS ++ L TP + L + + Sbjct: 454 IPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHH 505 Score = 83.3 bits (206), Expect = 3e-18 Identities = 79/515 (15%), Positives = 167/515 (32%), Gaps = 49/515 (9%) Query: 2 NLSAPFIARPVATMLLSLAILLLGGVSFGLLPVSPLPNMDFPVITVQASLP-GASPEIMA 60 N + +L+ I+ V F LP S LP D V LP GA+ E Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 61 SSVATPLERSL-------GSIAGVSQMT-SRSSQGSTRIIIQFDLDRDINGAARDVQAAI 112 + + L S+ V+ + S +Q + + + + A+ Sbjct: 588 KVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLK-PWEERNGDENSAEAV 646 Query: 113 NASRNLLPSGMR-------SMPTYRKINPSQAPIMVLSLTSEVLDKAELYDIGSTILAQK 165 + +R +MP ++ + L + + L + +L Sbjct: 647 IHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGL-GHDALTQARNQLLGMA 705 Query: 166 LSQVSGVGEIQVGGSS-LPAVRVELQPQQLEQYGVSLDEVRQTIANGNVRRPKGMVEDAD 224 + + ++ G ++E+ ++ + GVSL ++ QTI+ D Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 225 QHWQVRA---NDQLHQAADYTPLIIRYQDGAALRLGDVARVRDSVEDRYNSGFFNNEQAV 281 + ++ D L +R +G + + Y S + Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFT----TSHWVYGSPRLERYNGL 821 Query: 282 LLIV---NRQAGAN---IIETIEGIRRELPALQAIMPGSVDLNIAMDRSPVIRATLHEAE 335 + G + + +E + +LPA + + Sbjct: 822 PSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQ------------ERLSG 869 Query: 336 RTLLIAVGLVIVLVFLFLGRL----RTALIPALAVPVSLVGTFAVMYMFGFSLNVLSLMA 391 V + V+VFL L L + L VP+ +VG +F +V ++ Sbjct: 870 NQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVG 929 Query: 392 LILAAGLVVDDAIVVLENI-ARHIDDGMPPLKAAYVGTREVGFTLLSMNLSLVVVFVSIL 450 L+ GL +AI+++E +G ++A + R +L +L+ ++ + + Sbjct: 930 LLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLA 989 Query: 451 YMGGIVERLFREFSITLAAAILVSLLVSLTLTPML 485 G I + ++ + L+++ P+ Sbjct: 990 ISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVF 1024
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.1 bits (86), Expect = 1e-04 Identities = 36/249 (14%), Positives = 70/249 (28%), Gaps = 30/249 (12%) Query: 210 QTVEAYARSLRLTENQYRAGIVPRSDVSQAQTQLKSTQAQAIDLKWQRAQMEHAIAVLVG 269 ++V L+LT A D + Q+ L + + + +E + Sbjct: 116 ESVRKGDVLLKLTALGAEA------DTLKTQSSLLQARLEQTRYQILSRSIELNKLPELK 169 Query: 270 VAPSELGIAVREDIPPLPAIPLAVPSQLLERRPDIASAERQVMAANANIGVAEAAWYPEL 329 + V E + + + Q + E + A A Sbjct: 170 LPDEPYFQNVSE--EEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 330 TLSASGGYRNSSFSDLF---SVP--------NRFWSLGPQLALTLLDFGGRRAELERAEA 378 LS R FS L ++ N++ +L + +E+ A+ Sbjct: 228 NLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287 Query: 379 SYDQTVASYRQTVLNSFREVEDYLVQLRVLEEEAVVQREALEAAQESLRLIE-NQYRAGT 437 Y ++ +L+ R+ D + L L +E + + Sbjct: 288 EYQLVTQLFKNEILDKLRQTTDNIGLL----------TLELAKNEERQQASVIRAPVSVK 337 Query: 438 VDFLSVATV 446 V L V T Sbjct: 338 VQQLKVHTE 346
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.003 Identities = 34/207 (16%), Positives = 64/207 (30%), Gaps = 20/207 (9%) Query: 210 ELDVLRADARLAATEASLPQLRAQQARARNRIATLLGQRADQLAVDLAPRDLPAIAKALP 269 +L L A+A T++SL Q R +Q R + ++L P + + Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQ---ILSRSIELNKLPELKLPDEPYFQNVS-- 180 Query: 270 IGDPGELLRRRPDIRAAERQLAAATADVGVATADLFPRVSLSGFLGFIAGRGSQIGSSAA 329 E+LR I+ + R L I + + Sbjct: 181 ---EEEVLRLTSLIKEQFSTWQNQKYQKELNLDKK--RAERLTVLARINRYENLSRVEKS 235 Query: 330 QAWGVAP-----SISWAAF-DLGSVRARLRGAEADADAALASYEHQVLLALEESENAFSD 383 + + +I+ A + + + L E ++L A EE + Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 384 YANAQQRLLSLLRQSTASRAAARQAEI 410 + + +L LRQ+T E+ Sbjct: 296 F---KNEILDKLRQTTD-NIGLLTLEL 318
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1102 bits (2852), Expect = 0.0 Identities = 431/1044 (41%), Positives = 641/1044 (61%), Gaps = 17/1044 (1%) Query: 4 SQFFIRRPIFAAVLSLVILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETV 63 + FFIRRPIFA VL++++++ GA+++ QLP+++YP + PP V V AN+PGA+ + + +TV Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 ASPLEQAITGVEGMLYMSSQATADGKLTLTITFGLGTDLDNAQVQVQNRVTRTMPTLPTE 123 +EQ + G++ ++YMSS + + G +T+T+TF GTD D AQVQVQN++ P LP E Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 124 VQRLGVTVDKASPDLTMVVHLTSPDQRYDMLYLSNYAALNVKDELARLDGIGDVQLFGMG 183 VQ+ G++V+K+S MV S + +S+Y A NVKD L+RL+G+GDVQLFG Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-A 180 Query: 184 DYSLRVWLDPEKVASRNLTASDVVNAIREQNRQVAAGSLGAPPAPGATDFQLSINTQGRL 243 Y++R+WLD + + LT DV+N ++ QN Q+AAG LG PA SI Q R Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 244 VTEEEFENIIIRAGEDGSITRLRDIARVELGSSQYALRSLLNNQPAVAIPVFQRPGSNAI 303 EEF + +R DGS+ RL+D+ARVELG Y + + +N +PA + + G+NA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 304 EISDSVRARMAELKRDFPEGVDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQ 363 + + +++A++AEL+ FP+G+ YD T FV+ SI VV TL EAI+LV LV+ LFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 364 TWRASIIPLAAVPVSLIGTFAVMHLLGFSLNALSLFGLVLAIGIVVDDAIVVVENVER-N 422 RA++IP AVPV L+GTFA++ G+S+N L++FG+VLAIG++VDDAIVVVENVER Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 423 IGLGKSPEEATRQAMKEVTGPIIATALVLCAVFIPTAFISGLTGQFYQQFALTIAISTVI 482 + P+EAT ++M ++ G ++ A+VL AVFIP AF G TG Y+QF++TI + + Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 483 SAFNSLTLSPALAAALLRSHDAPKDGFSRLLDRIFGGWLFAPFNRMFDRASHGYVGLVRR 542 S +L L+PAL A LL+ A F FN FD + + Y V + Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKG--------GFFGWFNTTFDHSVNHYTNSVGK 532 Query: 543 ILRGSGIALVVYVGLVGLGYMGFASTPTGFVPPQDKQYLVAFAQLPDAATLDRTEDVIKR 602 IL +G L++Y +V + F P+ F+P +D+ + QLP AT +RT+ V+ + Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 603 MSEIAGKH--PGVENTVAFPGLSINGFTNSPNSGIVFTPLKPFDERKDPSLSANAIAADL 660 +++ K+ VE+ G S +G + N+G+ F LKP++ER SA A+ Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAVIHRA 650 Query: 661 NGQFAQIQDAFIAIFPPPPVQGLGTIGGFRVQVQDRGNLGYEELYSQVQNVIAKSADYP- 719 + +I+D F+ F P + LGT GF ++ D+ LG++ L ++ +A +P Sbjct: 651 KMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPA 710 Query: 720 ELAGLFTSYQVNVPQVDADIDREKAKTHGVPIDEIFDTMQVYLGSLYANDFNRFGRTYQV 779 L + + + Q ++D+EKA+ GV + +I T+ LG Y NDF GR ++ Sbjct: 711 SLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKL 770 Query: 780 NVQADQKFRLAPEQIGQLKVRNNRGEMVPLSTFVNVTDSAGPDRVMHYNGFLTAEINGAA 839 VQAD KFR+ PE + +L VR+ GEMVP S F G R+ YNG + EI G A Sbjct: 771 YVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEA 830 Query: 840 APGYSSGQAEAAMERLLKAELPNGMSYEWTELTYQQILAGNTAIFVFPLCVLLAFLVLAA 899 APG SSG A A ME L +LP G+ Y+WT ++YQ+ L+GN A + + ++ FL LAA Sbjct: 831 APGTSSGDAMALMENLAS-KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAA 889 Query: 900 QYESWSLPLAVILIVPMTLLSAITGVILAGSDNNVFTQIGLIVLVGLACKNAILIVEFAK 959 YESWS+P++V+L+VP+ ++ + L N+V+ +GL+ +GL+ KNAILIVEFAK Sbjct: 890 LYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAK 949 Query: 960 DKQE-EGMDRLAAILEACRLRLRPILMTSFAFIMGVVPLVLSSGAGAEMRHAMGVAVFSG 1018 D E EG + A L A R+RLRPILMTS AFI+GV+PL +S+GAG+ ++A+G+ V G Sbjct: 950 DLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGG 1009 Query: 1019 MLGVTFFGLLLTPVFYLVIRAFVE 1042 M+ T + PVF++VIR + Sbjct: 1010 MVSATLLAIFFVPVFFVVIRRCFK 1033
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 56.8 bits (137), Expect = 7e-11 Identities = 25/104 (24%), Positives = 45/104 (43%) Query: 64 SVEIRPRVSGFIDKAAFEEGALVKKGDLLFQIDPRPFQAEVKRLQAQLQQARAIQQRTVA 123 S EI+P + + + +EG V+KGD+L ++ +A+ + Q+ L QAR Q R Sbjct: 96 SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQI 155 Query: 124 EAERGERLRQKNAISAELADARVSAASEARSATAAIQAQLDRAQ 167 + E + + + + E T+ I+ Q Q Sbjct: 156 LSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Score = 42.1 bits (99), Expect = 3e-06 Identities = 18/129 (13%), Positives = 43/129 (33%), Gaps = 24/129 (18%) Query: 84 ALVKKGDLLFQIDPRPFQAEVKRLQAQLQQARAIQQRTVAEAERG-----ERLRQ----- 133 +L+ K + + E + + + + + + E E + Sbjct: 242 SLLHKQAI-----AKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF 296 Query: 134 KNAISAELADARVSAASEARSATAAIQAQLDRAQLDLSFTRVTAPIDGRV-GRALITSGN 192 KN I +L + + +L + + + + AP+ +V + T G Sbjct: 297 KNEILDKLRQTTDNIGL--------LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGG 348 Query: 193 LVNASEALL 201 +V +E L+ Sbjct: 349 VVTTAETLM 357
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (290), Expect = 4e-33 Identities = 77/260 (29%), Positives = 124/260 (47%), Gaps = 15/260 (5%) Query: 36 AGKLEGKTAIITGGDSGIGRSVAVLFAREGADV-AILYLDQHQDAEETRTVVEQYGRRCL 94 A +EGK A ITG GIG +VA A +GA + A+ Y + + + E R Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE--ARHAE 60 Query: 95 TFAGDVADRDVCRKVIDETLAAFGKLDILVNNAAEQHPQEKLEDISEEQWEKTFRTNIFG 154 F DV D ++ G +DILVN A P + +S+E+WE TF N G Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPG-LIHSLSDEEWEATFSVNSTG 119 Query: 155 MFQMTKAVLPHL--GKGASIINTTSVTAYKGSPQLLDYSATKGAITAFTRSLSMNLAERG 212 +F +++V ++ + SI+ S A + Y+++K A FT+ L + LAE Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 213 IRVNGVAPGPIWTPLISSTFDADEVAE---------FGSNTPMKRPGQPDEVAPAYVYLA 263 IR N V+PG T + S + + AE F + P+K+ +P ++A A ++L Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 264 SSDAAYVSGQVIHVNGGTVV 283 S A +++ + V+GG + Sbjct: 240 SGQAGHITMHNLCVDGGATL 259
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 27.0 bits (59), Expect = 0.011 Identities = 22/83 (26%), Positives = 32/83 (38%), Gaps = 7/83 (8%) Query: 16 TPTMAQFPAGTPRDDTGSRPSPMGNPTPQEEVETRKDHQ-GRTVTEDGRLVAPQPDSE-E 73 TP A+ P P + +P NP P E TR + + + D PD++ + Sbjct: 316 TPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDA-----NPDTDGQ 370 Query: 74 KSTDPDRHSAPGGPNDTSTDAGK 96 T PD + P PN K Sbjct: 371 PGTRPDSPAVPDRPNGRHRKERK 393
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 31.2 bits (70), Expect = 0.019 Identities = 19/92 (20%), Positives = 30/92 (32%), Gaps = 18/92 (19%) Query: 270 RLFTRNGHDWTAKMPQQAAALAGLGLESGWLD---GEVVVPN-----EEGTPDF---QAL 318 R+ G +W+ +PQ A + L+ + N E PD +AL Sbjct: 497 RVRVDTGSNWSEVLPQIQETTARIIFNGKDLNLVERRIAAVNPSDPLETTKPDMTLKEAL 556 Query: 319 QNAFEAGRSGNILYYLFDIPYLNGMDLRDVPL 350 + AF L Y G D+ + Sbjct: 557 KIAFGFNEPNGNLQY-------QGKDITEFDF 581
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.004 Identities = 10/54 (18%), Positives = 16/54 (29%) Query: 404 QALREARDAARDAADHTRRLYQEGRLAYLDSLDAERTLATAEAALAASQAQLSQ 457 + D L + +A L+ E A L ++QL Q Sbjct: 224 NRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 62.2 bits (151), Expect = 5e-13 Identities = 27/153 (17%), Positives = 56/153 (36%), Gaps = 6/153 (3%) Query: 84 ELAVDEARATVLERRAQLDQAQREARRNRMLKDLIAAETVEIGDTQVKRAAAALATAEAT 143 E EA + ++QL+Q + E + L+ ++++ + Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE 317 Query: 144 LGVAHLDLERTTVLSPVDGYLGD-QTMRVGDYVKTGTPVLSIV-DTDSLRVEGYFEETKL 201 L + + + +PV + + G V T ++ IV + D+L V + + Sbjct: 318 LAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDI 377 Query: 202 HAIEIGQPVDIHIMGEAQ----HLRGHVQSIAA 230 I +GQ I + +L G V++I Sbjct: 378 GFINVGQNAIIKVEAFPYTRYGYLVGKVKNINL 410 Score = 46.0 bits (109), Expect = 1e-07 Identities = 19/94 (20%), Positives = 38/94 (40%), Gaps = 7/94 (7%) Query: 50 VAPDVSGLVTELHVRDNQKVNRGQVLFVIDRARFELAVDEARATVLERRAQLDQAQREAR 109 + P + +V E+ V++ + V +G VL + A A L+ ++ L QA+ E Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALG-------AEADTLKTQSSLLQARLEQT 151 Query: 110 RNRMLKDLIAAETVEIGDTQVKRAAAALATAEAT 143 R ++L I + + ++ E Sbjct: 152 RYQILSRSIELNKLPELKLPDEPYFQNVSEEEVL 185
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.1 bits (182), Expect = 1e-17 Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 2/115 (1%) Query: 2 IRVLVVDDHDLVRTGISRMLADISGLQVIGQADSGEDAIRKARELKPDVVLMDVKMPGIG 61 +LV DD +RT +++ L+ +G V + R D+V+ DV MP Sbjct: 4 ATILVADDDAAIRTVLNQALSR-AGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLEATRKLLRSYPDLKVIAVTICEEDPFPTRLLQAGAAGYLTKGAGLEEMVQAIR 116 + ++ ++ PDL V+ ++ + + GA YL K L E++ I Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 666 bits (1719), Expect = 0.0 Identities = 205/1056 (19%), Positives = 435/1056 (41%), Gaps = 49/1056 (4%) Query: 5 LIRWSVLNRFLVLLATLLMTAVGVWAIRTTPIDALPDLSDVQVIIRTPYPGQAPQIVENQ 64 + + + + +++ G AI P+ P ++ V + YPG Q V++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 VTYPLTTTMLSVPGAKTVRGYSF-FGDSFVYVLFEDGTDLYWARSRVLEYLSQVQSRLPA 123 VT + M + + S G + + F+ GTD A+ +V L LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 124 SAK-PSLGPDATGVGWIFQYALVDRSGRHDLAQLRSLQDWFLKYELITLPNVAEVATIGG 182 + + + + ++ V + + +K L L V +V G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 183 MVKQYQVVLDPLKMASLAVTQAQVIEAIGMANQETGGAVLELAET------EYMVRASGY 236 ++ LD + +T VI + + N + L + A Sbjct: 181 Q-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 237 LQTLDDFRQIPLQLSAKGVPITLGDVAHVQLGPEMRRGIAELDGEGETVGGVVILRSGKN 296 + ++F ++ L++++ G + L DVA V+LG E IA ++G+ G + L +G N Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLATGAN 298 Query: 297 ARETLAAVHGKLEELKRSLPKGVEIVTTYDRSQLIDRAVENLSFKLLEEFIVVALVCGIF 356 A +T A+ KL EL+ P+G++++ YD + + ++ + L E ++V LV +F Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 357 LWHLRSSLVAIVSLPIGILIAFAVMRYQGINANIMSLGGIAIAIGAMVDAAVVMIENAHK 416 L ++R++L+ +++P+ +L FA++ G + N +++ G+ +AIG +VD A+V++EN + Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 417 KAEAWRHANPGRALAGDEHWRVMTSAAEEVGPALFFCLLIITLSFIPVFTLEAQEGRLFG 476 P A + ++ AL ++++ FIP+ G ++ Sbjct: 419 VMME-DKLPPKEATEK---------SMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYR 468 Query: 477 PLAFTKTYAMAAAAGLSVTLVPVLMGYWIR--GKLPDEARNPLNRGLIRVYRPA------ 528 + T AMA + +++ L P L ++ E + + + Sbjct: 469 QFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTN 528 Query: 529 -LNTVLDHPKTTIAVAVLVLATTLWPMSRLGGEFLPPMDEGDLLYMPSALPGLSAQKAAQ 587 + +L + + L++A + RL FLP D+G L M G + ++ + Sbjct: 529 SVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQK 588 Query: 588 LLQQTDR--MIRTVPEVETVFGKAGRAESATDPAPLEMFETTIRFKPREQW-RAGMTPEK 644 +L Q + VE+VF G + S F + KP E+ + E Sbjct: 589 VLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAF---VSLKPWEERNGDENSAEA 645 Query: 645 LVDELDRAVQVPGLTNIWIPPIRNRIDMLATGIKSPIGVKVAGANLEEIDRVSQQVEAVA 704 ++ + + + +++ + AG + + + Q+ +A Sbjct: 646 VIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMA 705 Query: 705 KRVPG-VSSALAERLVGGRYIDIDIDRRDAARYGLNIADVQSIVSSAIGGETVGETVEGL 763 + P + S L +++D+ A G++++D+ +S+A+GG V + ++ Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 764 ARYPISVRYPREWRDTPQALEELPILTPQGSQITLGSVARVRVSDGPPMLRSENARLAGW 823 + V+ ++R P+ +++L + + G + + G P L N G Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYN----GL 821 Query: 824 VYVDVRGRDIA-SVVADLRGAI-SADVALPPGMSLSYSGQFEFLERANERLKLVVPATLL 881 ++++G + D + + LP G+ ++G + + +V + + Sbjct: 822 PSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFV 881 Query: 882 IIFVLLYLTFSRLDEAVLIMLTLPFALTGGVWFLYLMGYNLSVATGVGFIALAGVAAEFG 941 ++F+ L + V +ML +P + G + L V VG + G++A+ Sbjct: 882 VVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNA 941 Query: 942 VIMLLYLKNAWAERQRDGLHDEAALCDAIREGAVQRVRPKAMTVAVIVAGLLPILLGAGT 1001 ++++ + K+ + + + +A R+RP MT + G+LP+ + G Sbjct: 942 ILIVEFAKDLMEKEGKG-------VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGA 994 Query: 1002 GSEVMSRIAAPMVGGMLSAPLLSLFVIPAVYRLMRK 1037 GS + + ++GGM+SA LL++F +P + ++R+ Sbjct: 995 GSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 81.4 bits (201), Expect = 1e-17 Identities = 85/537 (15%), Positives = 182/537 (33%), Gaps = 64/537 (11%) Query: 530 NTVLDHPKTTIAVAVLVLATTLWPMSRLGGEFLPPMDEGDLLYMP-----SALPGLSAQK 584 N + P +A++++ + +L P + P + PG AQ Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIA------PPAVSVSANYPGADAQT 56 Query: 585 AAQLLQQT-DRMIRTVPEVETVFGKAGRAESATDPAPLEMFETTIRFKPREQWRAGMTPE 643 + Q ++ + + + + + A S T T+ F+ G P+ Sbjct: 57 VQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVT---------ITLTFQS------GTDPD 101 Query: 644 K-LVDELDRAVQVPGLTNIWIPPIRNRIDMLATGIKSPIGVKVAGANLEEIDRVSQQVEA 702 V ++ L + ++ ++ G + D Sbjct: 102 IAQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASN 161 Query: 703 VA---KRVPGVSSALAERLVGGRY-IDIDIDRRDAARYGLNIADVQSIVSSA-------- 750 V R+ GV +L G +Y + I +D +Y L DV + + Sbjct: 162 VKDTLSRLNGVGDV---QLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQ 218 Query: 751 IGGETVGETVEGLARYPISVRYPREWRDTPQALEELPILT-PQGSQITLGSVARVR--VS 807 +GG + A R+ P+ ++ + GS + L VARV Sbjct: 219 LGGTPALPGQQLNASIIAQTRF-----KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGE 273 Query: 808 DGPPMLRSENARLAGWVYVDVRGRDIASVVADLRGAISADVA-LPPGMSLSY-SGQFEFL 865 + + R AG G + ++ ++ P GM + Y F+ Sbjct: 274 NYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFV 333 Query: 866 ERA-NERLKLVVPATLLIIFVLLYLTFSRLDEAVLIMLTLPFALTGGVWFLYLMGYNLSV 924 + + +E +K + A +L+ V+ + + ++ + +P L G L GY+++ Sbjct: 334 QLSIHEVVKTLFEAIMLVFLVMYLFLQN-MRATLIPTIAVPVVLLGTFAILAAFGYSINT 392 Query: 925 ATGVGFIALAGVAAEFGVIMLLYLKNAWAERQRDGLHDE-AALCDAIREGAVQRVRPKAM 983 T G + G+ + ++++ E + ++ +A + Q Sbjct: 393 LTMFGMVLAIGLLVDDAIVVV--------ENVERVMMEDKLPPKEATEKSMSQIQGALVG 444 Query: 984 TVAVIVAGLLPILLGAGTGSEVMSRIAAPMVGGMLSAPLLSLFVIPAVYRLMRKPRG 1040 V+ A +P+ G+ + + + +V M + L++L + PA+ + KP Sbjct: 445 IAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVS 501
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 1e-06 Identities = 34/179 (18%), Positives = 59/179 (32%), Gaps = 33/179 (18%) Query: 185 ARQRLRLAGMPAATIS-QLERTGKVSASITISTPIAGVLQELDVR-EGMSLAAGAPLARI 242 +LR ++ +L + + + I P++ +Q+L V EG + L I Sbjct: 300 ILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVI 359 Query: 243 NGLDSV-WLEVAVPEAQSTGIRVGQRATARLPAMPGER---IEGTITAVLPEANAASRT- 297 D + V I VGQ A ++ A P R + G + + +A R Sbjct: 360 VPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLG 419 Query: 298 --LRVRVQLPNPQGL-------LRPGLTAQATLKGADDTSVLLIPSEAVIRTGRRSLVM 347 V + + L G+ A I+TG RS++ Sbjct: 420 LVFNVIISIEENCLSTGNKNIPLSSGMAV-----------------TAEIKTGMRSVIS 461 Score = 30.6 bits (69), Expect = 0.014 Identities = 19/89 (21%), Positives = 34/89 (38%), Gaps = 16/89 (17%) Query: 205 TGKVSAS---ITISTPIAGVLQELDVREGMSLAAGAPLARINGLDS-------------V 248 GK++ S I +++E+ V+EG S+ G L ++ L + Sbjct: 87 NGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQA 146 Query: 249 WLEVAVPEAQSTGIRVGQRATARLPAMPG 277 LE + S I + + +LP P Sbjct: 147 RLEQTRYQILSRSIELNKLPELKLPDEPY 175
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.2 bits (133), Expect = 4e-10 Identities = 15/81 (18%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Query: 439 RLLVIDNETSILHSMAALLEQWGCTVVTATDEQTAIAALGGVAPDAILADYHLDHGSTGW 498 +LV D++ +I + L + G V ++ T + D ++ D + + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN-AF 63 Query: 499 DVVLALRARFSTRLPVVMITA 519 D++ ++ LPV++++A Sbjct: 64 DLLPRIKKARP-DLPVLVMSA 83
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 30.1 bits (68), Expect = 0.007 Identities = 15/60 (25%), Positives = 26/60 (43%) Query: 81 RSAAGLHASPNGQLTVALPLLMDLQIITPIALAYLNAFPDVQLNIQSSEGVPKLLKEGID 140 R+A GL P+ + LL+ + ++ PI F D + + K + EG+D Sbjct: 38 RNALGLQQIPSNMTLNGVALLLSMFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLD 97
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 30.3 bits (68), Expect = 0.005 Identities = 40/160 (25%), Positives = 57/160 (35%), Gaps = 21/160 (13%) Query: 9 NYRRYAPLTISTV-------LLCLFAVYLAMQIEQWMLLSRAPAPTDIYEQGTANPGGPD 61 N + PL+ S + L+ LF LAM + L AP + A Sbjct: 2 NISKLPPLSPSVIRRILFYLLMLLFCQQLAMIFWRIGLPDNAPVSSVQITPAQARQQPVT 61 Query: 62 MQRLEILFGSAAPTDAMAPSVAAS----------GFTLRGSFVHVEPQRSSAIVQVDGQP 111 + LFG +P A ++ AS +L G + RS AI+ D + Sbjct: 62 LNDFT-LFG-VSPEKNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQ 119 Query: 112 PRLYWQGEELSG-GVSLHKVYPDRVELLRNGTVEVLHFPQ 150 EE+ G + + PDRV L G EVL Sbjct: 120 FS-RGVNEEVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYS 158
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 531 bits (1370), Expect = 0.0 Identities = 206/618 (33%), Positives = 340/618 (55%), Gaps = 35/618 (5%) Query: 41 WTINLKDADIRAFIDQISQLSGQTFIVDPRVKGQVSVVSNATLSLSEVYQLFLSVMATHG 100 ++ + K DI+ FI+ +S+ +T I+DP V+G ++V S L+ + YQ FLSV+ +G Sbjct: 30 FSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLDVYG 89 Query: 101 FSVLTQGD-VARVVPNAEAKAEAG-----GGPSGGDQLETRVIQVQHTSAAELIPLIRPL 154 F+V+ + V +VV + +AK A P GD++ TRV+ + + +A +L PL+R L Sbjct: 90 FAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLLRQL 149 Query: 155 VPQFGHLAAVS--SANALIISDRSANIARIQNLVRQLDRAESNDYGVLNLQHGWAVDIAE 212 G + V +N L+++ R+A I R+ +V ++D A + L A D+ + Sbjct: 150 NDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPLSWASAADVVK 209 Query: 213 VLRN---SLMRGEAKTTAGVQIIADSRTNRLIFIGPSEARGKLASLAQTLDTPTTRSANT 269 ++ + + ++AD RTN ++ G +R ++ ++ + LD NT Sbjct: 210 LVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAMIKQLDRQQATQGNT 269 Query: 270 RVIRLRHNDAKSLAETLGDISEGLKNP-ESGEATTTRPQNILIRADESLNALVLLADPEL 328 +VI L++ A L E L IS +++ ++ + +NI+I+A NAL++ A P++ Sbjct: 270 KVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPDV 329 Query: 329 IGTMESIVRQLDVPRAQVMVEAAIVEVSGDITDALGVQWAVDARGSRGGAGGVNFGNTGI 388 + +E ++ QLD+ R QV+VEA I EV LG+QWA AG F N+G+ Sbjct: 330 MNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKN------AGMTQFTNSGL 383 Query: 389 SVGSVLNAINENEIPDNLP----------DGAIIGIGTRSFGALITALSSNSKSNLLSTP 438 + + + N+ + +G G ++ L+TALSS++K+++L+TP Sbjct: 384 PISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATP 443 Query: 439 SLLTLDNQEAEILVGQNVPFQTGSYTTDAAGANNPFTTIERQDIGVTLKVTPHINEGATL 498 S++TLDN EA VGQ VP TGS TT +N F T+ER+ +G+ LKV P INEG ++ Sbjct: 444 SIVTLDNMEATFNVGQEVPVLTGSQTT---SGDNIFNTVERKTVGIKLKVKPQINEGDSV 500 Query: 499 RLQIEQEISSIAPSASLTAQAVDLVTNKRAIKSTILAEDGQVIVLGGLIQDDVTRTNAKV 558 L+IEQE+SS+A +AS T+ + N R + + +L G+ +V+GGL+ V+ T KV Sbjct: 501 LLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKV 560 Query: 559 PLLGDIPLLGALFRSTQETHIKRNLMVFLRPTVIRDRAGLAALSGKKYSDIRVIETDSAS 618 PLLGDIP++GALFRST + KRNLM+F+RPTVIRDR S +Y+ ++ Sbjct: 561 PLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRG 620 Query: 619 ----PTILPANPTQLFDG 632 +L + +++ Sbjct: 621 KENNDAMLNQDLLEIYPR 638
>PERTACTIN#Pertactin signature. Length = 922 Score = 28.5 bits (63), Expect = 0.020 Identities = 20/63 (31%), Positives = 26/63 (41%) Query: 51 VVAEIEMQPVDVPEPEQEPGSVPEGFEIIEEDAEPATGPAIAEQAPAPIEPVVPVAPAAA 110 V A+ P P+P +PG P + +P P +APAP P AAA Sbjct: 563 VGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRELSAAA 622 Query: 111 PAA 113 AA Sbjct: 623 NAA 625
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 45.2 bits (107), Expect = 4e-07 Identities = 77/391 (19%), Positives = 140/391 (35%), Gaps = 39/391 (9%) Query: 21 LVVCLCALLLIFDGYDLFIYGVVLPVIMKEWGLTPLEAGALGSY-ALFGMM--FGALVFG 77 L+V L + L G L + VLP ++++ + G AL+ +M A V G Sbjct: 7 LIVILSTVALDAVGIGLIM--PVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 78 TLADRIGRKMGIAICFVLFSSATVLNGFASTPTEFGVFRFLAGLGCGGLMPNVVALMNEY 137 L+DR GR+ + + + + A + R +AG+ G A + + Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADI 123 Query: 138 APKKLRSTLVAVMFSGYSLGGMLSAGLGIYMLPRFGWEAMFFAAAVPLLLLPVIIWYLPE 197 R+ M + + G + LG M F AAA+ L + LPE Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 198 SVGFLVRQGRTEQARALLNKVDPTRQLGANDELVMSDIKGKSASVLELFRDGRGVRTVSI 257 S + R + AL + L FR RG+ V+ Sbjct: 184 SHK---GERRPLRREAL--------------------------NPLASFRWARGMTVVAA 214 Query: 258 WVAFFCCLLMVYALGSWLPKLMANAGYSL-GSSLSFLLALN--FGGMAGAILGGWLGDRF 314 +A F + +V + + L + + +++ LA +A A++ G + R Sbjct: 215 LMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARL 274 Query: 315 NLSKVVVVFFAISVVSISLLGFKTPMPVLYTLIFIAGATVIGTQILLYATAAQFYGLSIR 374 + +++ LL F T + + ++ + + IG L + Q Sbjct: 275 GERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQG 334 Query: 375 STGLGWASGIGRNGAIVGPLLGGALLGINLP 405 G + + +IVGPLL A+ ++ Sbjct: 335 QLQ-GSLAALTSLTSIVGPLLFTAIYAASIT 364 Score = 38.7 bits (90), Expect = 4e-05 Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 3/135 (2%) Query: 301 MAGAILGGWLGDRFNLSKVVVVFFAISVVSISLLGFKTPMPVLYTLIFIAGATVIGTQIL 360 A A + G L DRF V++V A + V +++ + VLY +AG T T + Sbjct: 57 FACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITG-ATGAV 115 Query: 361 LYATAAQFYGLSIRSTGLGWASGIGRNGAIVGPLLGGALLGINLPLQLNFMAFAVPGIIA 420 A A R+ G+ S G + GP+LGG + G + F A A + Sbjct: 116 AGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFS--PHAPFFAAAALNGLN 173 Query: 421 ALAMSVFAISSKRST 435 L S + Sbjct: 174 FLTGCFLLPESHKGE 188 Score = 30.6 bits (69), Expect = 0.012 Identities = 29/137 (21%), Positives = 61/137 (44%), Gaps = 7/137 (5%) Query: 60 ALGSYALFGMMFGALVFGTLADRIGRKMGIAICFVLFSSATVLNGFA-STPTEFGVFRFL 118 +L ++ + + A++ G +A R+G + + + + + +L FA F + L Sbjct: 251 SLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLL 310 Query: 119 AGLGCGGLMPNVVALMNEYAPK----KLRSTLVAVMFSGYSLGGMLSAGLGIYMLPRFGW 174 A G G MP + A+++ + +L+ +L A+ +G +L + + + Sbjct: 311 ASGGIG--MPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNG 368 Query: 175 EAMFFAAAVPLLLLPVI 191 A AA+ LL LP + Sbjct: 369 WAWIAGAALYLLCLPAL 385
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 87.4 bits (216), Expect = 1e-22 Identities = 73/265 (27%), Positives = 108/265 (40%), Gaps = 23/265 (8%) Query: 3 KRFQNKVAVITGAAQGIGRRVAERMGEEGGRLLLVD-RSELVHELADELGAKGVEVLTMT 61 K + K+A ITGAAQGIG VA + +G + VD E + ++ L A+ Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 62 ADLEQFADCHSVMDAAKARFGRVDILVNNVGGTIWAKPFEHYQEHEIEAEVRRSLFPTLW 121 AD+ A + + G +DILVN V G + + E EA + Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVN-VAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 122 CCHAALPHMLEQGAGAIVNVSSIA--TRSLNRVPYGAAKGGVNALTACLAFENAQRGVRV 179 + +M+++ +G+IV V S + Y ++K T CL E A+ +R Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 180 NATAPGGTEAPPRR---IPRNAAEQ-----SEQEKIWYQQIVDQTVDSSLMKRYGTIDEQ 231 N +PG TE + N AEQ E K +K+ + Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIP-----------LKKLAKPSDI 231 Query: 232 AGAILFLASDDASYITGVTLPVGGG 256 A A+LFL S A +IT L V GG Sbjct: 232 ADAVLFLVSGQAGHITMHNLCVDGG 256
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 236 bits (603), Expect = 8e-81 Identities = 72/229 (31%), Positives = 110/229 (48%), Gaps = 11/229 (4%) Query: 12 LKAGFVATVAMLGAA----PALAEEDPWEGVNRAVFRFN-DTVDTYTLKPLAKGYQKVTP 66 L A + T ++G A DP EG NR ++ FN + +D Y ++P+A ++ P Sbjct: 5 LSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVP 64 Query: 67 EFVEDGIGNVFSNLGDVIVLTNDLLQGKVRDAGIDTSRILFNTTFGVLGFFDVATRMGLH 126 + +G+ N NL + V+ N LQG + +R NT G+ GF DVA Sbjct: 65 QPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPK 124 Query: 127 K---NDEDFGQTLGAWGLGSGPYVVLPLLGPSTVRDAFGRVPDSFLEPYPHMEHVPTRNV 183 FG TLG +G+G GPYV LP G T+RD G + D+ + + Sbjct: 125 LQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPMSVGK 184 Query: 184 TRGVDLVDTRAGLLSAEKMIRG--DRYIFVRNAYLQNREFRVKDGEVED 230 ++ ++TRA LL ++ ++R D YI VR AY Q +F GE++ Sbjct: 185 W-TLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKP 232
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.5 bits (79), Expect = 5e-04 Identities = 19/74 (25%), Positives = 26/74 (35%), Gaps = 3/74 (4%) Query: 193 LAVSPSCPRPGVGEALVRHLIEHYMGRGLAYLDLSVLHDNQQAKALYAKLGFR--DLQTF 250 +AV+ + GVG AL+ IE L L N A YAK F + T Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTM 154 Query: 251 TVK-RKNSFNQPLF 263 + +F Sbjct: 155 LYSNFPTANEIAIF 168
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 57.5 bits (139), Expect = 1e-10 Identities = 26/119 (21%), Positives = 52/119 (43%), Gaps = 7/119 (5%) Query: 785 SEPCILVAEDNPVNQMVVRGLLKKRGYAVQLADNGRQAVDLYRRDPDAVQLILMDCEMPE 844 + ILVA+D+ + V+ L + GY V++ N L++ D MP+ Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD--GDLVVTDVVMPD 59 Query: 845 LDGFEASRQIRKLEADQQLQAVPIIAVTAHVLAEHRQRGLESGMDEFIGKPLESRQLYA 903 + F+ +I+K D +P++ ++A + E G +++ KP + +L Sbjct: 60 ENAFDLLPRIKKARPD-----LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG 113
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 47.9 bits (114), Expect = 4e-08 Identities = 69/321 (21%), Positives = 108/321 (33%), Gaps = 49/321 (15%) Query: 14 GITSFAPLIERIAEELALSRGLIS---LTTALPVLLMGLLAPLAPRLAVRFGLERSIALC 70 GI P++ + +L S + + + AL L+ AP+ L+ RFG R L Sbjct: 20 GIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFG--RRPVLL 77 Query: 71 LGLIAAALLLRLFGHSAALLI-----ATAGLVGAGIAVAGPLLSGFIK-----RYFLERM 120 + L AA+ + + L + AG+ GA AVAG ++ R+F Sbjct: 78 VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHF---- 133 Query: 121 GQTAAWYSLSMAVGGTLG-----VVVTAPATEAMGQEWTRGLALWALPALAALLIWLRLP 175 G +A + M G LG AP A A L Sbjct: 134 GFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAA---------AALNGLNFLTGCFLLPES 184 Query: 176 NQPETANDSR------AGLPWKE---PRAWLLSIYFALQAGLFYALATWLVARYHEVGYS 226 ++ E R A W A L++++F +Q A W++ + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWD 244 Query: 227 LLQSNAFFSGFMLIG-LPSAFAMPWLAQRLGNRHRIMAACGVLATLCLALIALLPGWQPL 285 + F ++ L A +A RLG R +M T + L GW Sbjct: 245 ATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAF 304 Query: 286 LVCMLLGV------ALNGTFS 300 + +LL AL S Sbjct: 305 PIMVLLASGGIGMPALQAMLS 325
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 79.3 bits (195), Expect = 1e-19 Identities = 51/183 (27%), Positives = 87/183 (47%), Gaps = 1/183 (0%) Query: 6 MITGAGSGLGREIALRWAREGWQLALSDVNEGGLAETLKMVREAGGDGFTMRCDVRDYSQ 65 ITGA G+G +A A +G +A D N L + + ++ DVRD + Sbjct: 12 FITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAA 71 Query: 66 LIAFAQACEEKLGGIDIVVNNAGVASGGFFDELSLEDWEWQIAINLMGVVKGCKAFLP-L 124 + E ++G IDI+VN AGV G LS E+WE ++N GV ++ + Sbjct: 72 IDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYM 131 Query: 125 VQKSKGKIINIASMAALMQAPGMSNYNVAKAGVVALSESLLVELRQAEVGVHVVCPSFFQ 184 + + G I+ + S A + M+ Y +KA V ++ L +EL + + ++V P + Sbjct: 132 MDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTE 191 Query: 185 TNL 187 T++ Sbjct: 192 TDM 194
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 32.5 bits (74), Expect = 0.003 Identities = 32/142 (22%), Positives = 52/142 (36%), Gaps = 31/142 (21%) Query: 80 PVKQLRYRLARQRGPAPLMFI-ISGTGAHYSAGKT--EALKRLFYGAGYHVVQLSSPTSY 136 PV+ A P + I +SG G + K L++ G+ VV SS Sbjct: 35 PVEPSTQVNAASSHTKPPLVIFLSGDGGWATLDKAVGGILQQ----QGWPVVGWSS---- 86 Query: 137 DFMSAASRY----ATPGISSDDAKDLYRVMQAVRAQQHKLQVTEFHLTGYSLGA--LNAA 190 +Y P D +D ++ +A+ +V L GYS GA + Sbjct: 87 ------LKYYWKQKDP---KDVTQDTLAIIDKYQAEFGTQKVI---LIGYSFGAEVIPFV 134 Query: 191 FVSQLDETRRSFNFKRVLLLNP 212 +++ R N +LL+P Sbjct: 135 L-NEMPARYRK-NVLGAVLLSP 154
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 188 bits (478), Expect = 1e-61 Identities = 69/202 (34%), Positives = 90/202 (44%), Gaps = 10/202 (4%) Query: 53 YDPFESINRRIYHFNYR-LDQWVMLPVVRGYRYVTPQPVRTGVSNFFGNLGEVPTLFNSL 111 DP E NR +Y+FN+ LD +++ PV +R PQP R G+SNF GNL E + N Sbjct: 29 SDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYF 88 Query: 112 AQLKAQRAANATARFLFNTILGVGGVWDPATRMGLPRQ---SEDFGQTLGYWGVPQGPYL 168 Q + RF NTILG+GG D A Q FG TLG++GV GPY+ Sbjct: 89 LQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYV 148 Query: 169 IIPALGPSNLRDATGRVADFAVERQMDFLQYSETTGGELSLTALRAINARHVTSFRYGQL 228 +P G LRD G +AD + + T + L I R G L Sbjct: 149 QLPFYGSFTLRDDGGDMAD-----ALYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLL 203 Query: 229 -NSPFEYEKVRYVYSRARDLLV 249 S Y VR Y + D + Sbjct: 204 RQSSDPYIMVREAYFQRHDFIA 225
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.0 bits (176), Expect = 1e-17 Identities = 26/157 (16%), Positives = 58/157 (36%) Query: 8 DKRDLILSKGARVMTRRGYHGTGVQEIVQAAGIPKGSFYHYFASKEDFALQALDYIYAPR 67 + R IL R+ +++G T + EI +AAG+ +G+ Y +F K D + + + Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 68 LERYRAALCNAPIAPRQRVLDYYADLVAHFARKEKPEYHCFIGSLSFEMAELCPPIAKRL 127 E P P + + ++ +E+ I E + + Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 128 SEILAQSVEQLARCLEQAQRAGEIESGCNCPALAEFI 164 + +S +++ + L+ A + + A + Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM 167
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 28.0 bits (62), Expect = 0.013 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Query: 4 AANKAVSIDYTLTNDAGEVIDSS-AGGAPLVYLHGAGNIIPGLEKALEGKQGGDQIQVAI 62 + V+++YT T G V DS+ G P + +IPG +AL+ G +V + Sbjct: 142 GKSDTVTVEYTGTLIDGTVFDSTEKAGKPATF--QVSQVIPGWTEALQLMPAGSTWEVFV 199 Query: 63 EPQDAYGEYS 72 AYG S Sbjct: 200 PADLAYGPRS 209
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 468 bits (1206), Expect = e-167 Identities = 184/397 (46%), Positives = 252/397 (63%), Gaps = 10/397 (2%) Query: 5 NILVINCGSSSIKFALVNEAQATFPLQGLAECIGSPEAVIHFESAAGKESVKVPNADHQA 64 ILVINCGSSS+K+ L+ +GLAE IG ++++ + K +K DH+ Sbjct: 2 KILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKD 61 Query: 65 ALAQILPRVEEAAGG------HLDGIGHRVVHGGEKFFASSLLNDETLAGIEANIQLAPL 118 A+ +L + + G +D +GHRVVHGGE F +S L+ D+ L I I+LAPL Sbjct: 62 AIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121 Query: 119 HNPANLSGIHAAINLFPELPQVGVFDTAFHQTMPEHAYRYAVPDVLYKEHGVRRYGFHGT 178 HNPAN+ GI A + P++P V VFDTAFHQTMP++AY Y +P Y ++ +R+YGFHGT Sbjct: 122 HNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGT 181 Query: 179 SHRFVSKRAAEMAGVPVENSSWLVAHLGNGCSTCAVVNGESRDTSMGLTPLEGLVMGTRS 238 SH++VS+RAAE+ P+E+ + HLGNG S AV NG+S DTSMG TPLEGL MGTRS Sbjct: 182 SHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRS 241 Query: 239 GDVDPSLHNFLNKTLGWDLAKIDNMLNKESGLKGLSGLSNDMRTLADAR-NAGHPGAVLA 297 G +DPS+ ++L + ++ N+LNK+SG+ G+SG+S+D R L DA G A LA Sbjct: 242 GSIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQLA 301 Query: 298 FDVFCYRLAKSLAAMSCALPQLDGLVFTGGIGENSSAVRERTLEHLKLFGFKLDAEANAR 357 +VF YR+ K++ + + A+ +D +VFT GIGEN +RE L+ L+ GFKLD E N Sbjct: 302 LNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNKV 361 Query: 358 CTRGVAGEIQAAGSP-RIMVVPTNEERQIALDTLALL 393 RG I A S +MVVPTNEE IA DT ++ Sbjct: 362 --RGEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIV 396
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.3 bits (180), Expect = 9e-16 Identities = 39/178 (21%), Positives = 69/178 (38%), Gaps = 31/178 (17%) Query: 14 TLLVVDDREANLVAMEALLGDGDWQVHTVNSGEAALKALLDLDVELVLLDVQMPGMDGFE 73 T+LV DD A + L + V ++ + + D +LV+ DV MP + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 74 V-ARLMRGSPHTRYTPIIFVSAIAHTRDSVLRGYATGAVDFILKPFDPQVLKHKINTLLA 132 + R+ + P P++ +SA T + ++ GA D++ KPFD L I LA Sbjct: 65 LLPRIKKARPD---LPVLVMSAQN-TFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 133 HEHNRRD------------------LQLLTQQLDSARAFNASVLSNAAEGILVVGEDG 172 R +Q + + L + ++ ++ GE G Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL--------MITGESG 170
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 1e-11 Identities = 31/123 (25%), Positives = 48/123 (39%), Gaps = 1/123 (0%) Query: 1109 PGQRVLLVDEDVRLIYSLTAQLDELGIQVVPATSAAEALERFDEDAFDLVVLDMSRPGAE 1168 G +L+ D+D + L L G V ++AA DLVV D+ P Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 1169 GPELARRLKQDHDCQAPIVALVGANDEGARERCSASGADEVLIKPVEATALRELLRRRLD 1228 +L R+K P++ + N + S GA + L KP + T L ++ R L Sbjct: 62 AFDLLPRIK-KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 1229 LES 1231 Sbjct: 121 EPK 123 Score = 54.1 bits (130), Expect = 2e-09 Identities = 22/138 (15%), Positives = 51/138 (36%), Gaps = 10/138 (7%) Query: 855 GPGLLIIEDDTDFASVVAEVGQSHGFTSLICNTGEQGLEALRREHFAAVILDILLPDISG 914 G +L+ +DD +V+ + G+ I + + V+ D+++PD + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 915 WQIHRELRGDERHQGMPVIIISCVPQPHDWHDDGSR----YLVKPVAQSELERIFIELAR 970 + + ++ + +PV+++S + YL KP +EL I + Sbjct: 63 FDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL----IGIIG 116 Query: 971 HEHNPLRLLLVEAEPRRR 988 + + E + Sbjct: 117 RALAEPKRRPSKLEDDSQ 134 Score = 50.6 bits (121), Expect = 3e-08 Identities = 15/69 (21%), Positives = 30/69 (43%) Query: 977 RLLLVEAEPRRRVLIRDYFERLGYSVTLAGSSDSARLAYAEQTFSVVVVDSELADGSGLD 1036 +L+ + + R ++ R GY V + ++ + A +VV D + D + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1037 LLDAFERLR 1045 LL ++ R Sbjct: 65 LLPRIKKAR 73
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 99.2 bits (247), Expect = 7e-27 Identities = 38/123 (30%), Positives = 56/123 (45%), Gaps = 11/123 (8%) Query: 105 TLIMPGNITFASNSADISSSFYPTLNSLVQVFKEFNKNG--VDIVGHTDSTGSLQLNQDL 162 + ++ F N A + L+ L + V ++G+TD GS NQ L Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGL 273 Query: 163 SNRRAQSVASYLVSNGVAPARISSYGAGPSQPIASNDTAAGR---------AQNRRVEIN 213 S RRAQSV YL+S G+ +IS+ G G S P+ N + A +RRVEI Sbjct: 274 SERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIE 333 Query: 214 LRP 216 ++ Sbjct: 334 VKG 336
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 542 bits (1399), Expect = 0.0 Identities = 273/347 (78%), Positives = 309/347 (89%), Gaps = 2/347 (0%) Query: 1 MFKKLRGMFSSDLSIDLGTANTLIYVRDRGIVLDEPSVVAIRSH--GNQKSVVAVGTEAK 58 M KK RGMFS+DLSIDLGTANTLIYV+ +GIVL+EPSVVAIR G+ KSV AVG +AK Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK 60 Query: 59 RMLGRTPGNINAIRPMKDGVIADFSVCEKMLQYFINKVHENSFLQPSPRVLICVPCKSTQ 118 +MLGRTPGNI AIRPMKDGVIADF V EKMLQ+FI +VH NSF++PSPRVL+CVP +TQ Sbjct: 61 QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ 120 Query: 119 VERRAIRESALGAGAREVFLIEEPMAAAIGAGLPVDEARGSMVVDIGGGTTEIALISLNG 178 VERRAIRESA GAGAREVFLIEEPMAAAIGAGLPV EA GSMVVDIGGGTTE+A+ISLNG Sbjct: 121 VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG 180 Query: 179 VVYAESVRVGGDRFDESIVTYVRRNYGSLIGESTAERIKQEIGTAFPGGELREVDVRGRN 238 VVY+ SVR+GGDRFDE+I+ YVRRNYGSLIGE+TAERIK EIG+A+PG E+RE++VRGRN Sbjct: 181 VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN 240 Query: 239 LAEGVPRSFTLNSNEVLEALQESLATIVQAVKSALEQSPPELASDIAERGLVLTGGGALL 298 LAEGVPR FTLNSNE+LEALQE L IV AV ALEQ PPELASDI+ERG+VLTGGGALL Sbjct: 241 LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL 300 Query: 299 RDLDKLLAQETGLPVIVAEEPLTCVARGGGRALEMMDRHAMDLLSTE 345 R+LD+LL +ETG+PV+VAE+PLTCVARGGG+ALEM+D H DL S E Sbjct: 301 RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 26.0 bits (57), Expect = 0.046 Identities = 11/29 (37%), Positives = 15/29 (51%) Query: 4 TRLTALLLLAILASGCADRQSTQPTKAPP 32 RL+AL L L GCA + Q ++ P Sbjct: 3 LRLSALALGTTLLVGCASSGTDQQGRSDP 31
>FIMBRILLIN#Porphyromonas gingivalis: fimbrillin protein signature. Length = 348 Score = 30.4 bits (68), Expect = 0.011 Identities = 13/38 (34%), Positives = 20/38 (52%) Query: 41 IGLTVVAFGTSAPETAVSVQASLNGSGDIAVGNVIGSN 78 I LT+ GT+ PE ++ A LN +A ++G N Sbjct: 308 IKLTITGPGTNNPENPITESAHLNVQCTVAEWVLVGQN 345
>FIMBRILLIN#Porphyromonas gingivalis: fimbrillin protein signature. Length = 348 Score = 29.6 bits (66), Expect = 0.017 Identities = 14/38 (36%), Positives = 20/38 (52%) Query: 41 IGLTVVAFGTSAPETAVSVQAALNGSGDIAIGNVVGSN 78 I LT+ GT+ PE ++ A LN +A +VG N Sbjct: 308 IKLTITGPGTNNPENPITESAHLNVQCTVAEWVLVGQN 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 114 bits (288), Expect = 2e-32 Identities = 32/111 (28%), Positives = 59/111 (53%) Query: 13 PHLLLVDDDPTFTRVMARAMSRRGLQVSIAGSAEEGLALAKQDIPDYAVLDLKMEGDSGL 72 +L+ DDD V+ +A+SR G V I +A D V D+ M ++ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 73 VLLPKLLELDPEMRVLILTGYSSIATAVEAIKRGACNYLCKPADADDVLAA 123 LLP++ + P++ VL+++ ++ TA++A ++GA +YL KP D +++ Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114 Score = 54.5 bits (131), Expect = 3e-11 Identities = 12/68 (17%), Positives = 28/68 (41%) Query: 114 PADADDVLAALLSQHADLDSLVPENPMSVDRLQWEHIQRVLSEHDGNISATARALGMHRR 173 ++ + + D + +++ I L+ GN A LG++R Sbjct: 405 SQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRN 464 Query: 174 TLQRKLQK 181 TL++K+++ Sbjct: 465 TLRKKIRE 472
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 49.9 bits (119), Expect = 9e-11 Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 8/89 (8%) Query: 4 RGFTLIELMIVVAIIGIIAAIAYPNYQEYVRSAKRADAETALMELGHFMERYYTANGKY- 62 RGFTL+E+M+V+ IIG++A++ PN A + A + ++ L + ++ Y N Y Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHYP 67 Query: 63 -----LKADGSAPALPFTEA--PKDGSTK 84 L++ AP LP A K+G K Sbjct: 68 TTNQGLESLVEAPTLPPLAANYNKEGYIK 96
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 25.7 bits (56), Expect = 0.033 Identities = 13/62 (20%), Positives = 24/62 (38%), Gaps = 7/62 (11%) Query: 43 EKLNEAALAKHPGATIEETE-----LEEEYGRYVYQLELR--DDKGVQWDLELDAKTGEV 95 + + + + P A + +EE R Y++ +R W +DA G+V Sbjct: 149 QDVADRVTKERPAAEEGKPTRLVIYPDEETPRLAYEVNVRFLTPVPGNWIYMIDAADGKV 208 Query: 96 LK 97 L Sbjct: 209 LN 210
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.0 bits (70), Expect = 0.018 Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 10/81 (12%) Query: 3 LSRLALAVALLP-GVQVFAADAEQELPSMLITSARQAEPRAQATAANTVFTRADIERLQA 61 ++L LA LLP VQ E+ S L+ + + N T+ DI A Sbjct: 108 QNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGF--------VSDNPGTTQDDISDYVA 159 Query: 62 RSVPELLRRVPGV-QVSSAGG 81 +V + L R+ GV V G Sbjct: 160 SNVKDTLSRLNGVGDVQLFGA 180
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 39.5 bits (92), Expect = 6e-06 Identities = 57/271 (21%), Positives = 99/271 (36%), Gaps = 40/271 (14%) Query: 2 RRLLLAALVS-------LASLPALAAERVVSLAPSLSEIMLELDAADRLVGVLDGGE--- 51 RRLL A +S A A+ R+V+L E++L L GV D Sbjct: 10 RRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVP--YGVADTINYRL 67 Query: 52 ---RPAALQSVPSVGRYGQVEMETLLSLRPDLVLLW------PDSVPRSQREQLQQFGI- 101 P SV VG + +E L ++P ++ P+ + R + F Sbjct: 68 WVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDG 127 Query: 102 -PVLVVEQTRLERLAEQFVVVGNAVNRAEEGERLAERFRQGLVELRRKYVRE--QPLRVF 158 L + + L +A+ +N E ++ + ++ ++V+ +PL + Sbjct: 128 KQPLAMARKSLTEMADL-------LNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 Query: 159 YQIWNRPLYTLGGQQIISEAIEVCGGQNVFADLT--LAAPQVSIEAVLA-RDPEVILAGS 215 I R + G + E ++ G N + T + VSI+ + A +D +V+ Sbjct: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 Query: 216 G-----AQLDEWQAWPQLSAVRDGRLLEVPD 241 L W + VR GR VP Sbjct: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPA 271
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.1 bits (83), Expect = 2e-05 Identities = 17/64 (26%), Positives = 21/64 (32%), Gaps = 2/64 (3%) Query: 73 STWLGKHGLYLEDLYVTPQQRGVGAGKAVLRYLAKLAVARGCGRFEWSVLDWNQPAIDFY 132 S W G +ED+ V R G G A+L + A D N A FY Sbjct: 84 SNWNGY--ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFY 141 Query: 133 ESIG 136 Sbjct: 142 AKHH 145
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.9 bits (98), Expect = 1e-06 Identities = 19/82 (23%), Positives = 38/82 (46%), Gaps = 14/82 (17%) Query: 2 NSALWVSKTGLAAQDKAMATVANNLANVNTNGFKSDRAVFEDLFYVIEKQPGAQADEINT 61 +S + + +GL A A+ T +NN+++ N G+ + A +T Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANST 46 Query: 62 VPSGIQLGSGVRVAGTQKVFTE 83 + +G +G+GV V+G Q+ + Sbjct: 47 LGAGGWVGNGVYVSGVQREYDA 68 Score = 39.6 bits (92), Expect = 9e-06 Identities = 14/47 (29%), Positives = 20/47 (42%) Query: 213 QLKQGVLEGSNVQVVEAMVAMIAIQRAYEANAKVLDAASGMQQFLNQ 259 QL S V + E + Q+ Y ANA+VL A+ + L Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 37.2 bits (86), Expect = 1e-04 Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 5/57 (8%) Query: 2 SFNIALTGLSAVNEQLNTIGNNIANSGTVGFKSSR----TNFGSLYA-ETQAMGVEV 53 N A++GL+A LNT NNI++ G+ +L A GV V Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYV 59 Score = 31.9 bits (72), Expect = 0.005 Identities = 14/47 (29%), Positives = 22/47 (46%) Query: 348 TLASGALESSNVDLTQQLVGLMEGQRNYQANTQVISTNKELTQVLFN 394 L++ S V+L ++ L Q+ Y AN QV+ T + L N Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 59.6 bits (144), Expect = 2e-13 Identities = 26/147 (17%), Positives = 54/147 (36%), Gaps = 5/147 (3%) Query: 3 RSSRKQEILQAALACFTEFGVEATTIEMIRDRSGASIGSLYHHFGNRERIIAALYLEGIG 62 +Q IL AL F++ GV +T++ I +G + G++Y HF ++ + + ++ Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 63 EYAALLEAGLIETL-DAEACVRLFVTSYIDWVVANPDWARFV-LHNRGRVEAGEMGEQLR 120 L + D + +R + ++ V + + GEM + Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 121 EVNRTHGE---RVGAILRRHRESGAFR 144 E R+ L+ E+ Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLP 155
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 31.3 bits (71), Expect = 0.004 Identities = 22/125 (17%), Positives = 43/125 (34%), Gaps = 14/125 (11%) Query: 49 DFANWLAERGYQVVTFDYLGMGRSRRMPLRQLNVDILDWARHDCSAVLAVAAEAAGELPL 108 L ++G+ VV + L ++ P + + D A++ G + Sbjct: 69 AVGGILQQQGWPVVGWSSLKYYWKQKDP-KDVTQDT--------LAIIDKYQAEFGTQKV 119 Query: 109 YWIGHSVGAQILPLVKGH--ERLTRIVTIAAGSGYWRENSPQIRNKAWLLWHGLA---PV 163 IG+S GA+++P V R + V A + + +I + + Sbjct: 120 ILIGYSFGAEVIPFVLNEMPARYRKNVLGAVLLSPSQSSDFEIHVSEMVTSDNQSARYLT 179 Query: 164 LTAVA 168 L V Sbjct: 180 LPEVN 184
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.4 bits (110), Expect = 1e-07 Identities = 58/301 (19%), Positives = 103/301 (34%), Gaps = 30/301 (9%) Query: 61 FAVFYTICGVPIGRLADRKSRRGIIAIGVLVWSLMTALCGTARTFWQFLVFRIGVGVGEA 120 +A+ C +G L+DR RR ++ + + ++ A+ TA W + RI G+ Sbjct: 52 YALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TG 110 Query: 121 ALSPSAYSLIADSFPPKLRGTAMSVYSMGIYIGSGLAFLLGGLVVKFASAQGDVELPVLG 180 A A + IAD R S G +LGGL +G Sbjct: 111 ATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL---------------MG 155 Query: 181 MVRPWQLIFLVLGAAGVLFTAVLLLIREPSRKGVGAGVEVPLSEVAG--YIRQNRRTVLC 238 P F G+ F L+ E + L+ +A + R Sbjct: 156 GFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAAL 215 Query: 239 HNFGFACLAFAAYGSSAWIPTFFIRTYGWSASDVGVLYGSVVAVAGSIGIIAGGRLSDLL 298 F ++ W+ F + W A+ +G+ +A G + +A ++ + Sbjct: 216 MAVFFIMQLVGQVPAALWV-IFGEDRFHWDATTIGI----SLAAFGILHSLAQAMITGPV 270 Query: 299 HRRGYRDAPLRVGIISAALTLPLNLAYLAGTGELALALIALHVFTIAMPFGVGPAAIQEI 358 R L +G+I+ L LA +A + + G+G A+Q + Sbjct: 271 AARLGERRALMLGMIADGTGYIL----LAFATRGWMAFPIMVLLAS---GGIGMPALQAM 323 Query: 359 M 359 + Sbjct: 324 L 324
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 51.7 bits (124), Expect = 9e-10 Identities = 32/163 (19%), Positives = 59/163 (36%), Gaps = 37/163 (22%) Query: 1 MKILITGSQGQLARELQLELAGKLLALGHNAL---------------------------- 32 MK L+TG+ G + ++ +LL GH + Sbjct: 1 MKYLVTGAAGFIG----FHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQF 56 Query: 33 ---NLADPEQIREQVRLVRPDLIINAAAYTAVDPAETHREQAFAVNARGPQVLAEEAARL 89 +LAD E + + + + + AV + + N G + E Sbjct: 57 HKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN 116 Query: 90 GVP-LIHYSTDYVFDGRKGEPYTEAD-VPQPLSVYGASKLAGE 130 + L++ S+ V+ + P++ D V P+S+Y A+K A E Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE 159
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 452 bits (1165), Expect = e-159 Identities = 178/480 (37%), Positives = 250/480 (52%), Gaps = 46/480 (9%) Query: 11 TQVLLIDDDPHLRQALSQTLDLAGLKVASLGDARELAARLPADWPGVVVSDIRMPGIDGL 70 +L+ DDD +R L+Q L AG V +A L + A +VV+D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 ELLQQLRARDSELPVILITGHGDIQLAVQAMRAGAYDFLEKPFPSEALLDSVRRALALRQ 130 +LL +++ +LPV++++ A++A GAYD+L KPF L+ + RALA + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 131 LVLDNRSLRLALADRQQLSARLLGQSKAMLRLREQIGALAGTQADVLILGETGAGKEVVA 190 D Q L+G+S AM + + L T ++I GE+G GKE+VA Sbjct: 124 RRPSKLE------DDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 191 RALHDLSNRRNGPFVAINAGALAESVVESELFGHEPGAFTGAQKRRIGKFEFANGGTLFL 250 RALHD RRNGPFVAIN A+ ++ESELFGHE GAFTGAQ R G+FE A GGTLFL Sbjct: 178 RALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFL 237 Query: 251 DEIESMSLDVQVKLLRLLQERVVERLGGNQSIALDIRVIAATKEDLRVAADQGRFRADLY 310 DEI M +D Q +LLR+LQ+ +GG I D+R++AAT +DL+ + +QG FR DLY Sbjct: 238 DEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLY 297 Query: 311 YRLNVAPLGIPPLRERNEDILLLFQHFAEAGAQRHGLPIRELQPEQRAALLRHAWPGNVR 370 YRLNV PL +PPLR+R EDI L +HF + A++ GL ++ E + H WPGNVR Sbjct: 298 YRLNVVPLRLPPLRDRAEDIPDLVRHFVQQ-AEKEGLDVKRFDQEALELMKAHPWPGNVR 356 Query: 371 ELQNTAERFAL---------------------------------------GLGLGLDQPG 391 EL+N R + + Q Sbjct: 357 ELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYF 416 Query: 392 AEPTSSVAGTGNLSEQVEAFERALIAAELNRPHGSLRSVAEALGVPRKTLHDKLRKHGLN 451 A ++ +G + E LI A L G+ A+ LG+ R TL K+R+ G++ Sbjct: 417 ASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.7 bits (139), Expect = 2e-12 Identities = 17/113 (15%), Positives = 44/113 (38%) Query: 11 RRPRASSQTRIRQILASARELLAEQGATTLSVYAVAERAGIPPSSVYHFFSGVPALLAAL 70 R+ + +Q + IL A L ++QG ++ S+ +A+ AG+ ++Y F L + + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 71 TADVHATFRASLEQPIDHQSLTSWRDLSRLIEQRMLAIYEQDSAARQLILVQH 123 + + L ++ + + ++ + ++ H Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFH 115