>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.7 bits (233), Expect = 2e-24 Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 1/124 (0%) Query: 4 KVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGME 63 ++V DD+ I +L L + GYDV + I + D+V+ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 VCREVRKKYE-MPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYS 122 + ++K +P+++++A+++ + + E GA DY+ KPF ELI + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 123 QPAQ 126 +P++ Sbjct: 125 RPSK 128
>PF01206#SirA family protein Length = 76 Score = 65.6 bits (160), Expect = 6e-16 Identities = 24/70 (34%), Positives = 39/70 (55%) Query: 118 KQFDFRGLQCPGPIVNISKEINNISTGEQIEVTVTDPGFNSDIKSWAKQTGNTLVNLTEE 177 + D GL CP PI+ K + ++ GE + V TDPG D +S++KQTG+ L+ EE Sbjct: 6 QSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKEE 65 Query: 178 ANVINAIIQK 187 + +++ Sbjct: 66 DGTYHFRLKR 75
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 101 bits (252), Expect = 8e-27 Identities = 34/124 (27%), Positives = 62/124 (50%), Gaps = 1/124 (0%) Query: 2 KTTLLVVEDDEAILHLIDVALTMNYYKVVTAKTGKEADFRLRTEQPDIILLDLGLPDIDG 61 T+LV +DD AI +++ AL+ Y V + D+++ D+ +PD + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 LSLIQQFRD-FVDTPIIVISARTEEQTIVEVLDRGANDYMTKPFNIDELRARIRVALRMS 120 L+ + + D P++V+SA+ T ++ ++GA DY+ KPF++ EL I AL Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 121 RSTE 124 + Sbjct: 123 KRRP 126
>PF06580#Sensor histidine kinase Length = 349 Score = 31.0 bits (70), Expect = 0.020 Identities = 9/56 (16%), Positives = 23/56 (41%), Gaps = 7/56 (12%) Query: 765 KLILQVLFNLIDNALKHAESHSE----IKLHVQHETNKIKFEMIDCGKGIPEEERQ 816 +++Q L ++N +KH + I L + + E+ + G + ++ Sbjct: 257 PMLVQTL---VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE 309
>PF01206#SirA family protein Length = 76 Score = 60.5 bits (147), Expect = 4e-14 Identities = 20/70 (28%), Positives = 37/70 (52%) Query: 118 KQFNYRGFQCPGPIVKISQEMKNIEVGDQIEVKVTDPGFPSDIKSWVKQTRHTLVKLDEN 177 + + G CP PI+K + + + G+ + V TDPG D +S+ KQT H L++ E Sbjct: 6 QSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKEE 65 Query: 178 NNGINAIIQK 187 + + +++ Sbjct: 66 DGTYHFRLKR 75
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 25.4 bits (55), Expect = 0.037 Identities = 12/38 (31%), Positives = 24/38 (63%) Query: 9 DLFLNHVNSNAVKTRKMMGEYIIYYDSVVIGGLYDNRL 46 ++F N V ++ ++ K + Y + D+++ GG YDN+L Sbjct: 57 EVFANRVITDDIELLKKILAYFLPEDAILKGGHYDNQL 94
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 70.4 bits (172), Expect = 7e-16 Identities = 47/191 (24%), Positives = 78/191 (40%), Gaps = 38/191 (19%) Query: 53 PKRVVTLYQGATDVAVSLGVKPVGAVES-----WTQKPKFEYIKNDLKDTKI-VGQEPAP 106 P R+V L ++ ++LG+ P G ++ W +P L D+ I VG P Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPP-------LPDSVIDVGLRTEP 87 Query: 107 NLEEISKLKPDLIVASKVRNEKVYDQLSKIAPTVSTDTVFKFKD----------TTKLMG 156 NLE ++++KP +V S + L++IAP F F D + M Sbjct: 88 NLELLTEMKPSFMVWS-AGYGPSPEMLARIAPGR----GFNFSDGKQPLAMARKSLTEMA 142 Query: 157 KALGKEKEAEDLLKKYDDKVAAFQKDAKAKY--KDAWPLKASVVNF-RADHTRIYA-GGY 212 L + AE L +Y+D F + K ++ + A PL + H ++ Sbjct: 143 DLLNLQSAAETHLAQYED----FIRSMKPRFVKRGARPL--LLTTLIDPRHMLVFGPNSL 196 Query: 213 AGEILNDLGFK 223 EIL++ G Sbjct: 197 FQEILDEYGIP 207
>SYCECHAPRONE#Gram-negative bacterial type III secretion SycE chaperone signature. Length = 130 Score = 31.2 bits (70), Expect = 0.002 Identities = 14/33 (42%), Positives = 16/33 (48%), Gaps = 1/33 (3%) Query: 25 VDALTEALTAHAHNDFVQ-PLKPYLRQDPENGH 56 +D E T +HN F Q LKP L D GH Sbjct: 54 LDNNDEKETLLSHNIFSQDILKPILSWDEVGGH 86
>PF04183#IucA / IucC family Length = 580 Score = 316 bits (812), Expect = e-103 Identities = 119/527 (22%), Positives = 208/527 (39%), Gaps = 46/527 (8%) Query: 79 RVSKQPLTAAEFWQTIANMNCDLSHEWEVARVEEGLTTAATQLAKQLSELDLASHPFV-- 136 R + +P+ A + + +S +++ T L + L++ + Sbjct: 66 RCADEPVLAQTLLMQLKQVL-SMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINL 124 Query: 137 -MSEQFASLKDRPFHPLAKEKRGLREADYQVYQAELNQSFPLMVAAVKKTHMIHGDTANI 195 L P K +RG + + Y E +F L AVK+ HMI + Sbjct: 125 NADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEM 184 Query: 196 DELENLTVPIKEQA----TDMLNDQGLSIDDYVLFPVHPWQYQHILPNVFATEISEKLVV 251 D + LT + Q + + + GL +++ PVHPWQ+Q + F + +E +V Sbjct: 185 DIHQLLTAAMDPQEFARFSQVWQENGLD-HNWLPLPVHPWQWQQKIATDFIADFAEGRMV 243 Query: 252 LLPLKFGD-YLSSSSMRSLIDIGAPYN-HVKVPFAMQSLGALRLTPTRYMKNGEQAEQLL 309 L +FGD +L+ S+R+L + +K+P + + R P RY+ G A + L Sbjct: 244 SLG-EFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWL 302 Query: 310 RQLIEKDEALAKYVMV-CDETA-------WWSYMGQDNDIFKDQLGHLTVQLRKYPEVLA 361 +Q+ D L + V E A ++ + + +++ LG V R+ P Sbjct: 303 QQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLG---VIWRENPCRWL 359 Query: 362 KNDTQQLVSMAALAANDRTLYQMICGKDNISKNDVMTLFEDIAQVFLKVTLSFM-QYGAL 420 K D + V MA L D + + S D T + +V + + +YG Sbjct: 360 KPD-ESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVA 418 Query: 421 PELHGQNILLSFEDGRVQKCVLRD-HDTVRIYKPWLTAHQLSLPKYV--VREDTPNTLIN 477 HGQNI L+ ++G Q+ +L+D +R+ K SLP+ V V + Sbjct: 419 LIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMD-SLPQEVRDVTSRLSADYLI 477 Query: 478 EDLETFFAYFQTLAVSVNLYAIIDAIQDLFGVSEHELMSLLKQILKNEVATISWVTTDQL 537 DL+T V + I + GV E LL +L + + Q+ Sbjct: 478 HDLQTGHF--------VTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMK-----KHPQM 524 Query: 538 AVRHILFDKQTWPFKQILLP---LLY-QRDSGGGSMPSGLTTVPNPM 580 + R LF +++L L + D G +P+ L + NP+ Sbjct: 525 SERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNPL 571
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 79.9 bits (197), Expect = 2e-18 Identities = 71/372 (19%), Positives = 149/372 (40%), Gaps = 24/372 (6%) Query: 13 ILWLSQFIAIAGLTVLVPLLPIYMASLQNLSVVEIQLWSGIAIAAPAVTTMIASPIWGKL 72 ++ + + G+ +++P+LP + L + ++ GI +A A+ +P+ G L Sbjct: 9 VILSTVALDAVGIGLIMPVLPGLLRDL--VHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 73 GDKISRKWMVLRALLGLAVCLFLMALCTTPLQFVLVRLLQGLFGGVVDASSAFASAEAPA 132 D+ R+ ++L +L G AV +MA + R++ G+ G + A+ + Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDG 126 Query: 133 EDRGKVLGRLQSSVSAGSLVGPLIGGVTASILGFSALLMSIAVITFIVCIFGALKLIETT 192 ++R + G + + G + GP++GG+ A + A + + + G L E+ Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLMGGF-SPHAPFFAAAALNGLNFLTGCFLLPESH 185 Query: 193 HMPKSQTPNINKGIRRSFQCLLCTQQTCRFIIVGVLANFAMYGMLTALSPLASSVNHTAI 252 + SF+ + V A A++ ++ + + +++ Sbjct: 186 KGERRPLRREALNPLASFR--------WARGMTVVAALMAVFFIMQLVGQVPAALWVIFG 237 Query: 253 DDR-----SVIGFLQSAF-WTASILSAPLWGRFNDKSYVKSVYIFATIACGCSAILQGLA 306 +DR + IG +AF S+ A + G + + + IA G IL A Sbjct: 238 EDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFA 297 Query: 307 TNIEFLMAARILQGLTYSAL--IQSVMFVVVNACHQ-QLKGTFVGTTNSMLVVGQIIGSL 363 T +L + +Q+++ V+ Q QL+G+ T+ + I+G L Sbjct: 298 TRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTS----LTSIVGPL 353 Query: 364 SGAAITSYTTPA 375 AI + + Sbjct: 354 LFTAIYAASITT 365
>PF04183#IucA / IucC family Length = 580 Score = 301 bits (772), Expect = 4e-97 Identities = 118/540 (21%), Positives = 212/540 (39%), Gaps = 63/540 (11%) Query: 3 NKELIQHAAYAAIERILNEYFREENLYQVPPQNHQWSIQLSELE-TLTGEFRYWSAMGHH 61 N + + ++L+E E+ + + ++ I L + E W G Sbjct: 2 NHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIW---GW- 57 Query: 62 MYHPEVWLIDGKSKKITTYKEAIARILQHMAQSADNQTA-VQQHMAQIMSDI--DNSIHR 118 ID ++ + +L + Q A V +HM + + + D + + Sbjct: 58 ------LWIDAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLK 111 Query: 119 TARYLQSNTIDYVEDRYIVSEQSLYLGHPFHPTPKSASGFSEADLEKYAPECHTSFQLHY 178 R L ++ + + Q L GHP K G+ + LE+YAPE +F+LH+ Sbjct: 112 ARRGLSASDL---INLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHW 168 Query: 179 LAVHQD-------------VLLTRYVEGKEDQVEKVLYQLADIDISEIPKDFILLPTHPY 225 LAV ++ LLT ++ +E ++Q +D +++ LP HP+ Sbjct: 169 LAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLD-----HNWLPLPVHPW 223 Query: 226 QINVLRQHPQYMQYSEQGLIKDLGVSGDLVYPTSSVRTVF--SKALNIYLKLPIHVKITN 283 Q ++ +G + LG GD S+RT+ S+ + +KLP+ + T+ Sbjct: 224 QWQQK-IATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTS 282 Query: 284 FIRTNDLEQIERTIDAAQVIASVKDE-----------VETPHFKLMFEEGYRALLPNPLG 332 R I A++ + V + P + EGY AL P Sbjct: 283 CYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYR 342 Query: 333 QTVEPEMDLLTNSAMIVREGIPNY-HADKDIHVLASLFETMPD-SPISKLAQVIEQSGLA 390 EM +I RE + D+ ++A+L E + P+ I++SGL Sbjct: 343 YQ---EM-----LGVIWRENPCRWLKPDESPVLMATLMECDENNQPL--AGAYIDRSGLD 392 Query: 391 PEAWLECYLDRTLLPILKLFSNTGISLEAHVQNTLIELKDGIPDVCFVRDLEG-ICLSRT 449 E WL ++P+ L G++L AH QN + +K+G+P ++D +G + L + Sbjct: 393 AETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKE 452 Query: 450 IATEKQLVPNVVAASSPVVYAHDEAWHRLKYYVVVNHLGHLVSTIGKATRNEVVLWQLVA 509 E +P V + + A D H L+ V L + + + E +QL+A Sbjct: 453 EFPEMDSLPQEVRDVTSRLSA-DYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQLLA 511
>PF04183#IucA / IucC family Length = 580 Score = 514 bits (1324), Expect = e-179 Identities = 146/592 (24%), Positives = 257/592 (43%), Gaps = 40/592 (6%) Query: 1 MNQTILNRVKTRVMHQLVSSLIYENIVVYKASYQDGVGHFTIEGHDSEYRFTAEKTHSFD 60 MN + V R++ +++S L YE + + A Q G + I +++RF AE+ + Sbjct: 1 MNHKDWDLVNRRLVAKMLSELEYEQV--FHAESQ-GDDRYCINLPGAQWRFIAERG-IWG 56 Query: 61 RIRITSPIERVVGDEADTTTDYTQLLREAVFTFPKNDEKLEQFIVELLQTELKDTQSMQY 120 + I + R AD LL + +D + + + +L T L D Q ++ Sbjct: 57 WLWIDAQTLRC----ADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKA 112 Query: 121 RESNPPATPETFN-DYEFYAMEGHQYHPSYKSRLGFTLSDNLKFGPDFVPNVKLQWLAID 179 R + N D + GH K R G+ ++ P++ +L WLA+ Sbjct: 113 RRGLSASDLINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVK 172 Query: 180 KDKVETTVSRNVVVNEMLRQQVGDKTYEHFVQQIEASGKHVNDVEMIPVHPWQFEHVIQV 239 ++ + + ++++L + + + F Q + +G N + +PVHPWQ++ I Sbjct: 173 REHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWL-PLPVHPWQWQQKIAT 231 Query: 240 DLAEERLNGTVLWLGESDELYHPQQSIRTMSPIDTT-KYYLKVPISITNTSTKRVLAPHT 298 D + G ++ LGE + + QQS+RT++ +K+P++I NTS R + Sbjct: 232 DFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRY 291 Query: 299 IENAAQITDWLKQIQQQDMYLKDE----LKTVFLGEVLGQSYLNTQLSPYKQTQVYGALG 354 I + WL+Q+ D L L G V + Y +PY+ ++ LG Sbjct: 292 IAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEM---LG 348 Query: 355 VIWRENIYHMLIDEEDAIPFNALYASDKDGLPFIEKWIKQYG--SEAWTKQFLAVAIRPM 412 VIWREN L +E + L D++ P +I + G +E W Q V + P+ Sbjct: 349 VIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPL 408 Query: 413 IHMLYYHGIAFESHAQNMMLIHENGWPTRIALKDFHDGVRFKREHLSEAASHLTLKPMPE 472 H+L +G+A +H QN+ L + G P R+ LKDF +R +E E S +P+ Sbjct: 409 YHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDS------LPQ 462 Query: 473 AHKKVNSNSFIETDDERLVRDFLH---DAFFFINIAEIILFIEKQYGIDEQRQWQWVKDI 529 + V S RL D+L F+ + I + + G+ E+R +Q + + Sbjct: 463 EVRDVTS---------RLSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQLLAAV 513 Query: 530 IEAYQEAFPELNN-YQHFDLFEPTIQVEKLTTRRL-LSDSELRIHHVTNPLG 579 + Y + P+++ + F LF P I L +L D + + N L Sbjct: 514 LSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLE 565
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 128 bits (323), Expect = 4e-38 Identities = 66/250 (26%), Positives = 113/250 (45%), Gaps = 2/250 (0%) Query: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64 K+A +TG AQGIG +A L G +A VD+N E + L ++ A A ADV + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAGVLWGIQAAH 124 + + + G ++VN AG+ I ++++E+++ + VN GV ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 125 EQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFAP 184 + G I+ S ++ Y S+K A T+ +LA I N +P Sbjct: 129 KYMMD-RRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 185 GIVQTPMMESIAVATAEEAGKPEAWGWEQFTSQIALGRVSQPEDVSNVVSFLAGKDSDYI 244 G +T M S+ + E F + I L ++++P D+++ V FL + +I Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSL-ETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 245 TGQTIIVDGG 254 T + VDGG Sbjct: 247 TMHNLCVDGG 256
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 217 bits (554), Expect = 9e-71 Identities = 79/327 (24%), Positives = 139/327 (42%), Gaps = 33/327 (10%) Query: 3 RVLITGGAGFIGSHLVDDL-QQDYDVYVLDNYRTG-----KRENIKSLADDHVF--ELDI 54 + L+TG AGFIG H+ L + + V +DN K+ ++ LA ++D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 55 REYDAVEQIMKTYQFDYVIHLAALVSVAESVEKPILSQEINVVATLRLLEIIKKYNSHIK 114 + + + + + F+ V ++V S+E P + N+ L +LE + I+ Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK--IQ 119 Query: 115 RFIFASSAAVYGDLPDLPKSDQSLI-LPLSPYAIDKYYGERTTLNYCSLYNIPTAVVKFF 173 ++ASS++VYG +P S + P+S YA K E Y LY +P ++FF Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 174 NVFGPRQDPKSQYSGVISKMFDSFEHNKPFTFFGDGLQTRDFVYVYDVVQSVRLIMEH-- 231 V+GP P M K + G RDF Y+ D+ +++ + + Sbjct: 180 TVYGPWGRPDMALFKFTKAML----EGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIP 235 Query: 232 ---------------KDAIGHGYNIGTGTFTNLLEVYRIIGELYGKSVEHEFKEARKGDI 276 A YNIG + L++ + + + G + + GD+ Sbjct: 236 HADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDV 295 Query: 277 KHSYADISNL-KALGFVPKYTVETGLK 302 + AD L + +GF P+ TV+ G+K Sbjct: 296 LETSADTKALYEVIGFTPETTVKDGVK 322
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.1 bits (73), Expect = 0.004 Identities = 61/337 (18%), Positives = 127/337 (37%), Gaps = 33/337 (9%) Query: 7 TLKVRLISNFLQLIITTAFIPFIALYLTDMLS----QSIVGIYLVGLVVLKFPLSIISGY 62 L V L + L + +P + L D++ + GI L +++F + + G Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 63 LIEIFPKKLLVLIYQATMVIMLVFMGVFGSHQLWQI-IGFCVAYAIFTIVWGLQFPVMDT 121 L + F ++ ++L+ A + M + LW + IG VA + G V Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMAT--APFLWVLYIGRIVAG-----ITGATGAVAGA 118 Query: 122 LIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGYSMLLLFLIAACIFLIVLFILY 181 I D D + + G +LGGLM G+S F AA + + Sbjct: 119 YIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGC 178 Query: 182 IWLPQDRNQVKQSDDKRHASRYQKLQIMNIFRSYKLVLKDRNYMLLISGFSIIMMGEFSI 241 LP+ ++ + + + L+ F + ++G+ Sbjct: 179 FLLPESHKGERRPLRREALNPLASFRWARGMTVVAA--------LMAVFFIMQLVGQVPA 230 Query: 242 SSYIAIRLKDQF--ETISIGSYDITGAKMLAILLMINTVVVILLTYSISKVVLKIDFKKA 299 + + I +D+F + +IG LA +++++ ++T ++ ++ ++A Sbjct: 231 ALW-VIFGEDRFHWDATTIGI-------SLAAFGILHSLAQAMITGPVAA---RLGERRA 279 Query: 300 LITGLLIYIVGYSGLTYLNQFGLLVVFMIIATVGEII 336 L+ G++ GY L + + + M++ G I Sbjct: 280 LMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIG 316
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 52.9 bits (127), Expect = 8e-09 Identities = 54/266 (20%), Positives = 101/266 (37%), Gaps = 55/266 (20%) Query: 2046 NTLLTGATGFLGAYLIEALQGYSHRIYCFIRADNEEIAWYKLMTNLNDYFS----EETVE 2101 L+TGA GF+G ++ + L H++ + D NLNDY+ + +E Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQV---VGID-----------NLNDYYDVSLKQARLE 47 Query: 2102 MM----LSNIEVIVGDFECMDDVVLPENMDTIIH----AGARTDHFGDDDEFEKVNVQGT 2153 ++ ++ + D E M D+ + + + R + + N+ G Sbjct: 48 LLAQPGFQFHKIDLADREGMTDLFASGHFERVFISPHRLAVR-YSLENPHAYADSNLTGF 106 Query: 2154 VDVIRLAQQHH-ARLIYVSTISV-GTYFDIDTEDVTFSEADVYKGQLLTSPYTRSKFYSE 2211 ++++ + + L+Y S+ SV G + FS D + S Y +K +E Sbjct: 107 LNILEGCRHNKIQHLLYASSSSVYG-----LNRKMPFSTDDSVDHPV--SLYAATKKANE 159 Query: 2212 LKVLEAVNN-GLDGRIVRVGNLTSPYNGRWHM------RNIKTNRFSMVMNDLLQLDCIG 2264 L + GL +R + P+ GR M + + + V N Sbjct: 160 LMAHTYSHLYGLPATGLRFFTVYGPW-GRPDMALFKFTKAMLEGKSIDVYNY-------- 210 Query: 2265 VSMAEMPVDFSFVDTTARQIVALAQV 2290 +M DF+++D A I+ L V Sbjct: 211 ---GKMKRDFTYIDDIAEAIIRLQDV 233
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 29.2 bits (65), Expect = 0.009 Identities = 15/57 (26%), Positives = 27/57 (47%), Gaps = 5/57 (8%) Query: 84 GQP-----IYVSLSYSYPYIVCVVDKEPVGIDIEKISQRLDWRTLVTCFSTNEAHQI 135 QP ++ S+S+ + V+ ++ +GIDIEKI + L ++ QI Sbjct: 76 RQPLWPDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATELAPSIIDSDERQI 132
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 31.7 bits (72), Expect = 0.002 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 7/84 (8%) Query: 155 INADTLAYFIASSLKAPIYV-LSNIAGVLIN-----DVVIPQLPLVDIHQYIEHGD-IYG 207 I+ D +A + A I++ L+++ G + + + ++ + ++ +Y E G G Sbjct: 213 IDKDLAGEKLAEEVNADIFMILTDVNGAALYYGTEKEQWLREVKVEELRKYYEEGHFKAG 272 Query: 208 GMIPKVLDAKNAIENGCPKVIIAS 231 M PKVL A IE G + IIA Sbjct: 273 SMGPKVLAAIRFIEWGGERAIIAH 296
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 59.6 bits (144), Expect = 4e-13 Identities = 31/99 (31%), Positives = 51/99 (51%) Query: 86 LDKRDDDFVIDKRHFSAFVGTDLDLQLRRRGIDTIVLGGVATHIGVDTTARDAYQLNYNQ 145 L DDD V+ K +SAF T+L +R+ G D +++ G+ HIG TA +A+ + Sbjct: 112 LAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKA 171 Query: 146 FFVTDMMSAQNETLHQFPIDNVFPLMGQTITTNDFLNIL 184 FFV D ++ + HQ ++ T+ T+ L+ L Sbjct: 172 FFVGDAVADFSLEKHQMALEYAAGRCAFTVMTDSLLDQL 210
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 30.4 bits (69), Expect = 0.002 Identities = 16/75 (21%), Positives = 28/75 (37%), Gaps = 15/75 (20%) Query: 86 ELIENESVETLKNKMIARATNTMRFVATNIMDAQIDAICDVLKNARTIFLFGFGASSLTI 145 +LI +A AT + + +DA A+ L + L GFG + Sbjct: 6 DLIA----------KVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVR- 54 Query: 146 GDLFQKLSRIGLNVR 160 ++ +R G N + Sbjct: 55 ----ERAARKGRNPQ 65
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 27.6 bits (61), Expect = 7e-04 Identities = 12/35 (34%), Positives = 17/35 (48%) Query: 1 MKRLLSLLLASALILSACGSNDGDKKGESKKTEKY 35 MK LS L +L C S+ D++G S E + Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGF 35
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 33.9 bits (77), Expect = 0.002 Identities = 47/240 (19%), Positives = 94/240 (39%), Gaps = 19/240 (7%) Query: 242 KQEIEQLENERIDIQNGAEEINLRNQLADKQSELKRIEANNSASNENKIHALTNELHVEN 301 ++EIE+ + E AE +LA E K +E K+ A +E+ + Sbjct: 157 RKEIEREKAETERQLKLAEAEE--KRLAALSEEAKAVEIAQK-----KLSAAQSEVVKMD 209 Query: 302 GTVANLKTRLKQNKQQITHEENRR-NQLLENHKGLKS--DLEKAKNQKFEYLDDNVCSCC 358 G + L +RL + E + E + +L++ + +D + + Sbjct: 210 GEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRP 269 Query: 359 GQQLPAEQVSEVREKALQKFNANKSKELETIQTSINHIISEGKKIKPIIEKLEDDNNNLQ 418 + +V K K K++ +T IN I ++ +I+ I ++ ++ N Sbjct: 270 FFEATRRRVGA------GKIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGI 323 Query: 419 IKINEAEERSARIQNKINKLKITHVDVTQTDEYKAVMLEINEINQKRSNIRKTIQDKVSG 478 +++EAEE + QN + +I Y+ + + E K S + + + DK G Sbjct: 324 ARVHEAEENLKKAQNNLLNSQIKDAVDATVSFYQTLTEKYGE---KYSKMAQELADKSKG 380
>PF06580#Sensor histidine kinase Length = 349 Score = 27.5 bits (61), Expect = 0.015 Identities = 9/36 (25%), Positives = 18/36 (50%), Gaps = 5/36 (13%) Query: 67 ERLEQARLERKLERQRKKEAELR----RKKPH-LFN 97 + +QA +++ +EA+L + PH +FN Sbjct: 142 KNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFN 177
>PF07520#Virulence protein SrfB Length = 1041 Score = 25.3 bits (55), Expect = 0.029 Identities = 8/24 (33%), Positives = 12/24 (50%), Gaps = 3/24 (12%) Query: 58 IELDEAVGIMTGQVVYKYEEAQEN 81 ++ DEA Q+VY Y E + Sbjct: 548 VDWDEAS---CTQLVYLYSELTQK 568
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 27.2 bits (60), Expect = 0.016 Identities = 16/81 (19%), Positives = 34/81 (41%), Gaps = 7/81 (8%) Query: 22 LLLFIKQITDLFGLDLSTQLNQASAIIGAILTLLTGIGVITDPTSKGVSDSSIAQTYQAP 81 +++ + + G L + + ++ + GV T+KG + + A Sbjct: 20 VVVVALLLVAIVGNYLYRDIMLPLRALAVVILIAAAGGVALL-TTKGKATVAFA------ 72 Query: 82 RDSSKEEQQVTWKTSQDTSLT 102 R++ E ++V W T Q+T T Sbjct: 73 REARTEVRKVIWPTRQETLHT 93
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 30.1 bits (68), Expect = 0.009 Identities = 28/167 (16%), Positives = 61/167 (36%), Gaps = 32/167 (19%) Query: 1 MNIMLTGATGHLGTHITNQAIANHIDHFHIGVRNVEKVPD----------DWRGKVSVRQ 50 M ++TGA G +G H++ + + H +G+ N+ D + + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEA--GHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHK 58 Query: 51 LDYFNQESMVEAFK--GMDTVVFI-------PSIIHP-SFKRIPEV--ENLVYAAKQSGV 98 +D ++E M + F + V S+ +P ++ N++ + + + Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 99 AHIIFIG---YYADQHNNPFHMS-----PYFGYASRLLSTSGIDYTY 137 H+++ Y PF P YA+ + + +TY Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTY 165
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 95.5 bits (237), Expect = 3e-26 Identities = 46/214 (21%), Positives = 84/214 (39%), Gaps = 11/214 (5%) Query: 18 TGVITSNVQSVQAKTEVKQQSESELKHYYNKPVLERKNVTGYKYTEKGKDYIDVIVDNQY 77 T V S+ Q ++ + +L +Y+ N + + + + + Sbjct: 25 TPVPLSSNQIIKTAKASTNDNIKDLLDWYSSGSDTFTNS---EVLDNSLGSMRIKNTDGS 81 Query: 78 SQISLVGSDKDKFKDGDNSNIDVFILREGDSRQATN-----YSIGGVTKTNSQPFIDYIH 132 + + S +D+ R S+ + + I GVT T P I Sbjct: 82 ISLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLP--TPIE 139 Query: 133 TPILEIKKGKEEPQSSLYQIYKEDISLKELDYRLRERAIKQHGLYSNGLKQGQI-TITMK 191 P+ GK+ P + K+ +++ LD+ +R + + HGLY + K G ITM Sbjct: 140 LPLKVKVHGKDSPLKYGPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMN 199 Query: 192 DGKSHTIDLSQKLEKERMGDSIDGRQIQKILVEM 225 DG ++ DLS+K E I+ +I+ I E+ Sbjct: 200 DGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 87.0 bits (215), Expect = 5e-23 Identities = 39/203 (19%), Positives = 77/203 (37%), Gaps = 22/203 (10%) Query: 37 ISENSKKLKAYYTQPSIEYKNVTGYISFIQPSIKFMNIIDGNSVNNLALIGKDKQHYHTG 96 ++N K L +Y+ S + N + S+ M I + + +L + Sbjct: 42 TNDNIKDLLDWYSSGSDTFTN----SEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFT 97 Query: 97 VHRNLNIFYVN-----EDKRFEGAKYSIGGITSANDKA--VDLIAEARVIKADHIGEYDY 149 +++ + I G+T+ ++L + +V D +Y Sbjct: 98 KGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYGP 157 Query: 150 DFFPFKIDKEAMSLKEIDFKLRKYLIDNYGLYGEMST----GKITVKKKYYGKYTFELDK 205 F DK+ +++ +DF++R L +GLY KIT+ Y +L K Sbjct: 158 KF-----DKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDG--STYQSDLSK 210 Query: 206 KLQEDRMSDVINVTDIDRIEIKV 228 K + + IN+ +I IE ++ Sbjct: 211 KFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 93.6 bits (232), Expect = 2e-24 Identities = 44/223 (19%), Positives = 78/223 (34%), Gaps = 21/223 (9%) Query: 140 TPQPMQSTKSDTPQSPTIKQAQTDMTPKYEDLRAYYTKPSFEFEKQFGFLLKPWTTVRFM 199 TP P+ S + IK A+ +DL +Y+ S F L ++R Sbjct: 25 TPVPLSSNQ-------IIKTAKASTNDNIKDLLDWYSSGSDTF-TNSEVLDNSLGSMRIK 76 Query: 200 NVIPNRFIYKIALVGKDEKKYKDGPYDNIDVF-----IVLEDNKYQLKKYSVGGITKTNS 254 N + + + + +D+ ++ + + G+T T Sbjct: 77 NTDGSI---SLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEK 133 Query: 255 KKVDHKAELSVTKKDNQGMISRDVSEYMITKEEISLKELDFKLRKQLIEKHNLYGNM--G 312 + L V + K+++++ LDF++R QL + H LY + Sbjct: 134 LPTPIELPLKVKVHGKDSPLKYG---PKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKT 190 Query: 313 SGTIVIKMKNGGKYTFELHKKLQEHRMADVIEGTNIDKIEVNI 355 G I M +G Y +L KK + + I I IE I Sbjct: 191 GGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 101 bits (252), Expect = 8e-28 Identities = 45/216 (20%), Positives = 81/216 (37%), Gaps = 13/216 (6%) Query: 82 TKVETPQSPTTKQVPTEINPKFKDLRAYYTKPSLEFKNEIGIILKKWTTIRFMNIVPDYF 141 T V + K N KDL +Y+ S F N ++ ++R N Sbjct: 25 TPVPLSSNQIIKTAKASTNDNIKDLLDWYSSGSDTFTN-SEVLDNSLGSMRIKNTDGSI- 82 Query: 142 IYKIALVGKDDKKYDEGVHRNVDVFVVLEEKNKYGVE----RYSVGGITKSNSKKVDHKA 197 + + VD+ +K+++ E + + G+T + + Sbjct: 83 --SLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIEL 140 Query: 198 GVRITKEDNKGTISHDVSEFKITKEQISLKELDFKLRKQLIENHNLYGNV--GSGKIVIN 255 +++ + + K K+Q+++ LDF++R QL + H LY + G I Sbjct: 141 PLKVKVHGKDSPLKYG---PKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKIT 197 Query: 256 MKNGGKYTFELHKKLQENRMADVIDGTNIDNIEVNI 291 M +G Y +L KK + N I+ I IE I Sbjct: 198 MNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 135 bits (340), Expect = 2e-41 Identities = 49/201 (24%), Positives = 73/201 (36%), Gaps = 14/201 (6%) Query: 39 NVTKDIFDLRDYYSGASKELKNVTGYRYSKGGKHYLIFDKNRKFTRVQIFGKDIERFKAR 98 + +I DL D+YS S N S G + + IF Sbjct: 41 STNDNIKDLLDWYSSGSDTFTNSEVLDNSLGS---MRIKNTDGSISLIIFPSPYYSPAFT 97 Query: 99 KNPGLDI-----FVVKEAENRNGTVFSYGGVTKKNQDAYYDYINAPRFQIKRDEGDGIAT 153 K +D+ + F GVT + I P +K D Sbjct: 98 KGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLP--TPIELPLK-VKVHGKDSPLK 154 Query: 154 YGRVHYIYKEEISLKELDFKLRQYLIQNFDLYKKFPKDSKI-KVIMKDGGYYTFELNKKL 212 YG K+++++ LDF++R L Q LY+ K K+ M DG Y +L+KK Sbjct: 155 YG--PKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKF 212 Query: 213 QTNRMSDVIDGRNIEKIEANI 233 + N I+ I+ IEA I Sbjct: 213 EYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 192 bits (488), Expect = 1e-63 Identities = 49/197 (24%), Positives = 82/197 (41%), Gaps = 16/197 (8%) Query: 42 DIKDLYRYYSSESFEFSNI--------SGKVENYNGSNVVRFNQEKQNHQLFLLGKDKDK 93 +IKDL +YSS S F+N S +++N +GS + F G+ Sbjct: 45 NIKDLLDWYSSGSDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGE---- 100 Query: 94 YKKGLEGQNVFVVKELIDPNGRLSTVGGVTKKNNKSSETNTHLFVNKVYGGNLDASIDSF 153 K L + + + + GVT + L V KV+G + Sbjct: 101 -KVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELPLKV-KVHGKDSPLKYGP- 157 Query: 154 LINKEEVSLKELDFKIRKQLVEKYGLYKGTTKYGKI-TINLKDEKKEVIDLGDKLQFERM 212 +K+++++ LDF+IR QL + +GLY+ + K G I + D DL K ++ Sbjct: 158 KFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTE 217 Query: 213 GDVLNSKDIQNIAVTIN 229 +N +I+ I IN Sbjct: 218 KPPINIDEIKTIEAEIN 234
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 125 bits (314), Expect = 2e-37 Identities = 47/199 (23%), Positives = 73/199 (36%), Gaps = 19/199 (9%) Query: 42 DTNKLHQYYSGPSYELTNV--------SGQSQGYYDSNVLLFNQQNQKFQVFLLGKDENK 93 + L +YS S TN S + + S L+ F G+ Sbjct: 45 NIKDLLDWYSSGSDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGE---- 100 Query: 94 YKEKTHGLDVFAVPELVDLDGRIFSVSGVTKKNVKSIFESLRTPNLLVKKIDDKDGFSID 153 K + + F +SGVT L L K+ KD + Sbjct: 101 -KVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELP----LKVKVHGKDSP-LK 154 Query: 154 EFFFIQKEEVSLKELDFKIRKLLIKKYKLYEGSA-DKGRIVINMKDENKYEIDLSDKLDF 212 K+++++ LDF+IR L + + LY S G I M D + Y+ DLS K ++ Sbjct: 155 YGPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEY 214 Query: 213 ERMADVINSEQIKNIEVNL 231 IN ++IK IE + Sbjct: 215 NTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 130 bits (329), Expect = 1e-39 Identities = 39/197 (19%), Positives = 69/197 (35%), Gaps = 15/197 (7%) Query: 43 INMLHQYYSEESFESTNISVKSEDYYGSNVLNFNQRNKTFKVFLLGDDKNKY------KE 96 I L +YS S TN V + + + + + K Sbjct: 46 IKDLLDWYSSGSDTFTNSEVLD---NSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGEKV 102 Query: 97 KTHGLDVFAVPELIDIKGGIYSVGGITKKNVRSVFGFVSNPSLQVKKVDAKHGFSINELF 156 + + + + G+T + P L+VK F Sbjct: 103 DLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLP--TPIELP-LKVKVHGKDSPLKYGPKF 159 Query: 157 FIQKEEVSLKELDFKIRKMLVEKYRLYKGAS-DKGRIVINMKDEKKYVIDLSEKLSFDRM 215 K+++++ LDF+IR L + + LY+ + G I M D Y DLS+K ++ Sbjct: 160 --DKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTE 217 Query: 216 FDVMDSKQIKNIEVNLN 232 ++ +IK IE +N Sbjct: 218 KPPINIDEIKTIEAEIN 234
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 193 bits (491), Expect = 4e-64 Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%) Query: 31 KQNQKSVNKHDKEALYRYYTGKTMEMKNISALKHGKNNLRFKFRGIKIQVLLPGNDKSKF 90 K + S N + K+ L Y +G + N L + ++R K I +++ + Sbjct: 36 KTAKASTNDNIKDLLDWYSSG-SDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSP 94 Query: 91 QQRSYEGLDVFFVQEKRDKHD-----IFYTVGGVIQNNKTSGVVSAPILNISKEKGEDAF 145 E +D+ + K+ +H I + + GV K + P L + K G+D+ Sbjct: 95 AFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELP-LKV-KVHGKDSP 152 Query: 146 VKGYPYYIKKEKITLKELDYKLRKHLIEKYGLYKTISKDGRV-KISLKDGSFYNLDLRSK 204 +K Y K+++ + LD+++R L + +GLY++ K G KI++ DGS Y DL K Sbjct: 153 LK-YGPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKK 211 Query: 205 LKFKYMGEVIESKQIKDIEVNL 226 ++ I +IK IE + Sbjct: 212 FEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 108 bits (270), Expect = 4e-31 Identities = 47/225 (20%), Positives = 86/225 (38%), Gaps = 19/225 (8%) Query: 16 LTTGMITTTAQPVKASTLEVRSQAT-------QDLSEYYKGRGFELTNVTGYKYG-NKVT 67 L T PV S+ ++ A +DL ++Y TN + Sbjct: 15 LLLATTATDFTPVPLSSNQIIKTAKASTNDNIKDLLDWYSSGSDTFTNSEVLDNSLGSMR 74 Query: 68 FIDNSQQIDVTLTGNE----KLTVKDDDEVSNVDVFVVREGSDKSAITTSIGGITKTNGT 123 + I + + + T + +++ + S+ + I I G+T T Sbjct: 75 IKNTDGSISLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTE-- 132 Query: 124 QHKDTVQNVNLSVSKSTGQHTTSVTSEYYSIYKEEISLKELDFKLRKHLIDKHDLYKTEP 183 T + L V K G+ S K+++++ LDF++R L H LY++ Sbjct: 133 -KLPTPIELPLKV-KVHGK--DSPLKYGPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSD 188 Query: 184 KDSKI-RITMKNGGYYTFELNKKLQPHRMGDTIDSRNIEKIEVNL 227 K +ITM +G Y +L+KK + + I+ I+ IE + Sbjct: 189 KTGGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEI 233
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 31.5 bits (71), Expect = 0.002 Identities = 17/83 (20%), Positives = 34/83 (40%), Gaps = 9/83 (10%) Query: 177 INSNVPSYDAKFKMSNKDENVKQLRSRYNIPTDKAPILKMHIDGDLKGSSVGYKKLEIDF 236 +N VP Y+AK D V Q + RY + + + S G +++ Sbjct: 124 VNEEVPGYNAKIVSIRPDRVVLQYQGRYEV---------LGLYSQEDSGSDGVPGAQVNE 174 Query: 237 SKEENSELSIVDSLNFQPAKNKD 259 ++ + ++ D ++F P N + Sbjct: 175 QLQQRASTTMSDYVSFSPIMNDN 197
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 34.6 bits (79), Expect = 3e-04 Identities = 18/83 (21%), Positives = 34/83 (40%), Gaps = 9/83 (10%) Query: 181 INENVPSYDAKFKMSNKDENVKQLRSRYNIPTDKAPVLKMHIDGDLKGSSVGYKKLEIDF 240 +NE VP Y+AK D V Q + RY + + + S G +++ Sbjct: 124 VNEEVPGYNAKIVSIRPDRVVLQYQGRYEV---------LGLYSQEDSGSDGVPGAQVNE 174 Query: 241 SKGEKSDLSVIDSLNFQPAKVDE 263 +++ ++ D ++F P D Sbjct: 175 QLQQRASTTMSDYVSFSPIMNDN 197
>adhesinb#Adhesin B signature. Length = 310 Score = 27.1 bits (60), Expect = 0.014 Identities = 21/94 (22%), Positives = 40/94 (42%), Gaps = 14/94 (14%) Query: 14 DISTTVETLNLISKMEAQKENIRSVIAPEHKHKYKDIENGLKGEE---KVLIEQMAQHCE 70 +S V+ + L + E KE+ H + ++ENG+ + K L E+ + E Sbjct: 118 AVSEGVDVIYLEGQSEKGKED---------PHAWLNLENGIIYAQNIAKRLSEKDPANKE 168 Query: 71 AFKANFKGAAQ--GDWVKSAMSEIDSIKDDLKKI 102 ++ N K + K A + ++I + K I Sbjct: 169 TYEKNLKAYVEKLSALDKEAKEKFNNIPGEKKMI 202
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 36.8 bits (85), Expect = 5e-07 Identities = 14/55 (25%), Positives = 28/55 (50%) Query: 6 SFFKGVKSEMEKTSWPTKEELFKYTVIVVSTVIFFLVFFYALDLGITALKNLLFG 60 +F + ++E+ K WPT++E T+IV + + + LD + L + + G Sbjct: 70 AFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVSFITG 124
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 47.2 bits (112), Expect = 3e-09 Identities = 20/97 (20%), Positives = 35/97 (36%), Gaps = 3/97 (3%) Query: 50 EYITSPHKVIFVAESDEQLVGFAFVNTTPFQRIKHVAKIDLGVKKLYQHRGIGQALLDAI 109 Y+ K F+ + +G + + + + D+ V K Y+ +G+G ALL Sbjct: 58 SYVEEEGKAAFLYYLENNCIGRIKIRSN-WNGYALIE--DIAVAKDYRKKGVGTALLHKA 114 Query: 110 MAWCLNNQIHRIEANVPLNNQPALELFKSADFQIEGV 146 + W N + N A + F I V Sbjct: 115 IEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAV 151
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.7 bits (155), Expect = 5e-14 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 1/111 (0%) Query: 3 ILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYW 62 IL+ +DD + L + L + ++V + + + + ++V+ DV +P + F Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 63 CRKMREV-SNVPILFLSSRDNPMDQVMSMELGADDYMQKPFYTNVLIAKLQ 112 ++++ ++P+L +S+++ M + + E GA DY+ KPF LI + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF05272#Virulence-associated E family protein Length = 892 Score = 36.2 bits (83), Expect = 1e-04 Identities = 15/56 (26%), Positives = 26/56 (46%), Gaps = 8/56 (14%) Query: 40 GPSGSGKTTLLNVLSSIDYISQGSITLKGKK--LEKLSNK------ELSDIRKHDI 87 G G GK+TL+N L +D+ S + K E+++ E++ R+ D Sbjct: 603 GTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRRADA 658
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 56.4 bits (136), Expect = 7e-11 Identities = 73/365 (20%), Positives = 134/365 (36%), Gaps = 41/365 (11%) Query: 9 KNYKLFVA--NMFLLGMGIAVTVPYLVLFATKDLGMTTNQ---YGLLLASAAISQFTVNS 63 N L V + L +GI + +P L +DL + + YG+LLA A+ QF Sbjct: 3 PNRPLIVILSTVALDAVGIGLIMPVLP-GLLRDLVHSNDVTAHYGILLALYALMQFACAP 61 Query: 64 IIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYA 123 ++ SD F R+ +++++L A+ ++I +W+ + + I G+ Sbjct: 62 VLGALSD--RFGRRPVLLVSLAGAAVDYAIMATAPFLWV-LYIGRIVAGITGATGA---V 115 Query: 124 SARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISIILFT 183 + +++ +RA+ + + F G + GP +G + G +A F L Sbjct: 116 AGAYIADITDGDERARHFG-FMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNF 174 Query: 184 LVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTL--------LLPFIAFILLHIGQWM 235 L + ++ + + A N L + FI+ +GQ Sbjct: 175 LTGCFLLPESHK-----GERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVP 229 Query: 236 YTMNMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIIL-GVLSSRLHTRTLLIYGAIFGG 294 + +F D + +G + L ++ G +++RL R L+ G I G Sbjct: 230 AAL-WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADG 288 Query: 295 LFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQ 354 Y + +M F + L GIG +P S GQ Sbjct: 289 TGYILLAFATRGWM-----AFPIMVLLASGGIG-------MPALQAMLSRQVDEERQ-GQ 335 Query: 355 LGGNL 359 L G+L Sbjct: 336 LQGSL 340 Score = 48.7 bits (116), Expect = 2e-08 Identities = 44/186 (23%), Positives = 73/186 (39%), Gaps = 13/186 (6%) Query: 213 MFKDKTLLLPFIAFILLHIGQWMYTMNMPLFVTDYLKENEQ--HVGYLASLCAGLEVPFM 270 M ++ L++ L +G + +P + D + N+ H G L +L A ++ Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 271 IILGVLSSRLHTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISY 330 +LG LS R R +L+ + Y + +++ G++ I A G +Y Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AY 119 Query: 331 FQDILPD-----FPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGM 385 DI G+ S F MV G + G L+GG H FF +AA L Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPH-----APFFAAAALNGLNF 174 Query: 386 ILIFFT 391 + F Sbjct: 175 LTGCFL 180
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 44.2 bits (104), Expect = 1e-09 Identities = 23/76 (30%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Query: 1 MHTFLIVLLIIDCIALITVVLLQEGKSSGLSGAISGGAE-QLFGKQKQRGVDLFLNRLTI 59 M+ L+V+ +I I L+ +++LQ+GK + + + GA LFG G F+ R+T Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG---SSGSGNFMTRMTA 57 Query: 60 ILSILFFVLMICISYL 75 +L+ LFF++ + + + Sbjct: 58 LLATLFFIISLVLGNI 73
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 26.7 bits (59), Expect = 0.049 Identities = 13/37 (35%), Positives = 19/37 (51%), Gaps = 2/37 (5%) Query: 135 MYDIYP-PYDGIPDEAFLI-KELKVNSLAGKTGTINY 169 D+ P P GI L KE+K++ +A GT+ Y Sbjct: 305 AVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGY 341
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 40.5 bits (94), Expect = 3e-05 Identities = 59/290 (20%), Positives = 108/290 (37%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSA--SDSDSASDSDSASDS 609 G + + SD G S + DS +G ST +G DS+ + S + SD Sbjct: 325 GSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDL 384 Query: 610 DSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 669 + S + +DS+ + S + +S + S + SD + S + Sbjct: 385 TAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGD 444 Query: 670 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 729 DS + S + DS + S + SD + S S + +S + S Sbjct: 445 DSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQ 504 Query: 730 DSDSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDS 789 + S + S ++++SD + S S + ++S + S + +S + Sbjct: 505 TAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGY 564 Query: 790 DSDSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S + SD +G S ++ SDS + GS + S+ + GS Sbjct: 565 GSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGS 614 Score = 40.5 bits (94), Expect = 3e-05 Identities = 54/266 (20%), Positives = 100/266 (37%) Query: 575 SDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSD 634 S + GSD T+ GS + DS+ + S + DS + S + SD Sbjct: 422 STQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLT 481 Query: 635 SASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSD 694 + S S + +S+ + S + S + S + ++SD + S S + ++ Sbjct: 482 AGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGAN 541 Query: 695 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSESDSDSD 754 S + S + +S + S + SD + S + SDS + S Sbjct: 542 SSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQT 601 Query: 755 SDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDSDSDSDSASDSDSGSDSDSSSDSD 814 + S + S + S + S S + +DS + S +G +S ++ Sbjct: 602 ASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYG 661 Query: 815 SDSTSDTGSDNDSDSDSNSDSESGSN 840 S T+ GSD + S S + + S+ Sbjct: 662 STQTAQEGSDLTAGYGSTSTAGADSS 687 Score = 40.5 bits (94), Expect = 3e-05 Identities = 58/290 (20%), Positives = 106/290 (36%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSD--SASDSDSASDS 609 G + + SD G S + +DS +G ST +G +S + S + SD Sbjct: 373 GSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDL 432 Query: 610 DSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 669 + S + DS+ + S + DS + S + SD + S S + Sbjct: 433 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGY 492 Query: 670 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 729 +S + S + S + S + ++SD + S S + ++S + S Sbjct: 493 ESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQ 552 Query: 730 DSDSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDS 789 + +S + S + SD + S + SDS + S + S + Sbjct: 553 TASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGY 612 Query: 790 DSDSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S + S +G S S++ +DS + GS + +S + GS Sbjct: 613 GSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGS 662 Score = 39.7 bits (92), Expect = 5e-05 Identities = 58/290 (20%), Positives = 106/290 (36%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSD- 610 G + + SD G S + +DS +G ST +G +S + S + SD Sbjct: 277 GSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDL 336 Query: 611 -SASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 669 + S + DS+ + S + DS + S + SD + S + + Sbjct: 337 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGA 396 Query: 670 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 729 DS + S + +S + S + SD + S + DS + S Sbjct: 397 DSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQ 456 Query: 730 DSDSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDS 789 + DS + S ++ SD + S S + +S + S + S + Sbjct: 457 TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGY 516 Query: 790 DSDSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S + + SD +G S S++ ++S + GS + +S + GS Sbjct: 517 GSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGS 566 Score = 39.7 bits (92), Expect = 6e-05 Identities = 59/290 (20%), Positives = 104/290 (35%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSD- 610 G + + SD G S + DS +G ST +G DS+ + S + SD Sbjct: 229 GSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDL 288 Query: 611 -SASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 669 + S + +DS+ + S + +S + S + SD + S + Sbjct: 289 TAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGD 348 Query: 670 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 729 DS + S + DS + S + SD + S + +DS + S Sbjct: 349 DSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQ 408 Query: 730 DSDSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDS 789 + +S + S ++ SD + S + DS + S + DS + Sbjct: 409 TAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGY 468 Query: 790 DSDSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S + SD +G S S++ +S + GS + S + GS Sbjct: 469 GSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGS 518 Score = 39.0 bits (90), Expect = 1e-04 Identities = 51/266 (19%), Positives = 97/266 (36%) Query: 575 SDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSD 634 S + GSD T+ GS + +DS+ + S + +S + S + SD Sbjct: 374 STQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLT 433 Query: 635 SASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSD 694 + S + DS+ + S + DS + S + SD + S S + + Sbjct: 434 AGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYE 493 Query: 695 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSESDSDSD 754 S + S + S + S + ++SD + S S + ++S + S Sbjct: 494 SSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQT 553 Query: 755 SDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDSDSDSDSASDSDSGSDSDSSSDSD 814 + +S + S + SD + S + SDS + S + S ++ Sbjct: 554 ASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYG 613 Query: 815 SDSTSDTGSDNDSDSDSNSDSESGSN 840 S T+ S + S S + + S+ Sbjct: 614 STQTAREQSVLTTGYGSTSTAGADSS 639 Score = 38.6 bits (89), Expect = 1e-04 Identities = 59/290 (20%), Positives = 107/290 (36%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSA--SDSDSASDSDSASDS 609 G + + SD G S + DS +G ST +G DS+ + S + SD Sbjct: 421 GSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDL 480 Query: 610 DSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 669 + S S + +S+ + S + S + S + + SD + S S + + Sbjct: 481 TAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGA 540 Query: 670 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 729 +S + S + +S + S + SD + S + SDS + S Sbjct: 541 NSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQ 600 Query: 730 DSDSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDS 789 + S + S + S + S S + +DS + S + +S + Sbjct: 601 TASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGY 660 Query: 790 DSDSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S + SD +G S S++ +DS + GS + +S + GS Sbjct: 661 GSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGS 710 Score = 38.2 bits (88), Expect = 2e-04 Identities = 59/290 (20%), Positives = 108/290 (37%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDS 611 G + EDS G S + S +G ST +G+DS+ + S + +S Sbjct: 261 GSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQ 320 Query: 612 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDS 671 + S + SD + S + DS+ + S + DS + S + Sbjct: 321 TAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQK 380 Query: 672 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 731 SD + S + +DS + S + +S + S + SD + S Sbjct: 381 GSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTG 440 Query: 732 DSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDS 791 + DS+ + S + DS + S + SD + S S + ES + Sbjct: 441 TAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGY 500 Query: 792 DSDSDSASDSD--SGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S + S +G S ++ ++SD + GS + + ++S+ + GS Sbjct: 501 GSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGS 550 Score = 38.2 bits (88), Expect = 2e-04 Identities = 59/278 (21%), Positives = 109/278 (39%), Gaps = 6/278 (2%) Query: 569 SGSDSNSDSGSDS------GSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSD 622 +G DS+ +G S GSD T+ GS S + +S+ + S + S + Sbjct: 458 AGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYG 517 Query: 623 SASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSD 682 S + + SD + S S + ++S+ + S ++ +S + S + SD Sbjct: 518 STQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLT 577 Query: 683 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSD 742 + S + SDS + S + S + S + S + S S + +D Sbjct: 578 AGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGAD 637 Query: 743 SDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDSDSDSDSASDSD 802 S + S + +S + S ++ SD + S S + +DS + S Sbjct: 638 SSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQT 697 Query: 803 SGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGSN 840 +G +S ++ S T+ GSD S S S + + S+ Sbjct: 698 AGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSS 735 Score = 38.2 bits (88), Expect = 2e-04 Identities = 58/290 (20%), Positives = 103/290 (35%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDS 611 G E + S G S + +DS +G ST +G +S+ + S SD Sbjct: 181 GSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQMAGYGSTQTGMKGSDL 240 Query: 612 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDS 671 + S + S + S + DS+ + S + SD + S + + Sbjct: 241 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGA 300 Query: 672 DSD--SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 729 DS + S + +S + S + SD + S + DS + S Sbjct: 301 DSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQ 360 Query: 730 DSDSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDS 789 + DS + S ++ SD + S + +DS + S + +S + Sbjct: 361 TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGY 420 Query: 790 DSDSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S + SD +G S ++ DS + GS + DS+ + GS Sbjct: 421 GSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGS 470 Score = 38.2 bits (88), Expect = 2e-04 Identities = 58/290 (20%), Positives = 110/290 (37%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDS 611 G + E+S G S + S +G ST +G DS+ + S + DS Sbjct: 405 GSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSL 464 Query: 612 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDS 671 + S + SD + S S + +S+ + S + S + S + + Sbjct: 465 TAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQN 524 Query: 672 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 731 +SD + S S + ++S + S + +S + S + SD + S Sbjct: 525 ESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTG 584 Query: 732 DSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDS 791 + SDS+ + S + S + S + S + S S + ++S + Sbjct: 585 TAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGY 644 Query: 792 DSDSDSASDS--DSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S + +S +G S ++ SD T+ GS + + +DS+ + GS Sbjct: 645 GSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGS 694 Score = 37.4 bits (86), Expect = 3e-04 Identities = 57/301 (18%), Positives = 101/301 (33%), Gaps = 3/301 (0%) Query: 542 PVVPEQPDEPGEIEP-IPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSA 600 P P+ E +P D D +SGS + + + ST S + Sbjct: 122 PGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQTIEIATYGSTLSGTHQSQLIAGYG 181 Query: 601 SDSDSASDSD--SASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSD 658 S + S + S + +DS + S + +S + S SD Sbjct: 182 STETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQMAGYGSTQTGMKGSDLT 241 Query: 659 SASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 718 + S + DS + S + DS + S + SD + S + +D Sbjct: 242 AGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGAD 301 Query: 719 SDSDSDSDSDSDSDSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSD 778 S + S + +S + S ++ SD + S + DS + S Sbjct: 302 SSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQT 361 Query: 779 SDSDSESDSDSDSDSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESG 838 + DS + S + SD +G S ++ +DS + GS + +S + G Sbjct: 362 AGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYG 421 Query: 839 S 839 S Sbjct: 422 S 422 Score = 37.4 bits (86), Expect = 3e-04 Identities = 60/290 (20%), Positives = 111/290 (38%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSD- 610 G + + SD G S S + +S +G ST +G S + S + ++SD Sbjct: 469 GSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDL 528 Query: 611 -SASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 669 + S S + ++S+ + S ++ +S + S + SD + S + S Sbjct: 529 ITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGS 588 Query: 670 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 729 DS + S + S + S + S + S S + +DS + S Sbjct: 589 DSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQ 648 Query: 730 DSDSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDS 789 + +S + S ++ SD + S S + +DS + S + +S + Sbjct: 649 TAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGY 708 Query: 790 DSDSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S + SD SG S S++ +DS + GS + S+ + GS Sbjct: 709 GSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGS 758 Score = 37.4 bits (86), Expect = 3e-04 Identities = 60/284 (21%), Positives = 109/284 (38%), Gaps = 4/284 (1%) Query: 560 DSDSDPGSDSGSDSNSDSGSD--SGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDS 617 +S + GS + GSD +G ST +G DS+ + S + DS + S Sbjct: 315 GEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGS 374 Query: 618 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDS 677 + SD + S + +DS+ + S + +S + S + SD + Sbjct: 375 TQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTA 434 Query: 678 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 737 S + DS + S + DS + S + SD + S S + +S Sbjct: 435 GYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYES 494 Query: 738 ASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDSDSDSDS 797 + + S + S + S + ++SD + S S + + S + S + Sbjct: 495 SLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTA 554 Query: 798 ASDS--DSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 + +S +G S ++ SD T+ GS + SDS+ + GS Sbjct: 555 SYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGS 598 Score = 37.4 bits (86), Expect = 3e-04 Identities = 58/290 (20%), Positives = 110/290 (37%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDS 611 G + EDS G S + S +G ST +G+DS+ + S + +S Sbjct: 357 GSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQ 416 Query: 612 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDS 671 + S + SD + S + DS+ + S + DS + S + Sbjct: 417 TAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQK 476 Query: 672 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 731 SD + S S + +S + S + S + S + ++SD + S S Sbjct: 477 GSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTS 536 Query: 732 DSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDS 791 + ++S+ + S + +S + S + SD + S + S+S + Sbjct: 537 TAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGY 596 Query: 792 DSDSDSASDSD--SGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S ++ S +G S ++ S T+ GS + + +DS+ + GS Sbjct: 597 GSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGS 646 Score = 35.9 bits (82), Expect = 8e-04 Identities = 68/328 (20%), Positives = 127/328 (38%), Gaps = 4/328 (1%) Query: 561 SDSDPGSDSGSDSNSDSGSD--SGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSA 618 DS + GS + GSD +G STS +G +S+ + S + S + S Sbjct: 460 EDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGST 519 Query: 619 SDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSD 678 + + SD + S S + ++S+ + S ++ +S + S + SD + Sbjct: 520 QTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAG 579 Query: 679 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSA 738 S + SDS + S + S + S + S + S S + +DS+ Sbjct: 580 YGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSS 639 Query: 739 SDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDSDSDSDSA 798 + S + +S + S + SD + S S + ++S + S + Sbjct: 640 LIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAG 699 Query: 799 SDS--DSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGSNNNVVPPNSPKNGTNAS 856 +S +G S ++ SD TS GS + + +DS+ + GS +S G ++ Sbjct: 700 YNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGST 759 Query: 857 NKNEAKDSKEPLPDTGSEDEANTSLIWG 884 + + S A++SLI G Sbjct: 760 QTAREQSVLTTGYGSTSTAGADSSLIAG 787 Score = 35.9 bits (82), Expect = 8e-04 Identities = 54/259 (20%), Positives = 95/259 (36%) Query: 582 GSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDS 641 GSD T+ GS + DS+ + S + DS + S + SD + S Sbjct: 237 GSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTG 296 Query: 642 ASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 701 + +DS+ + S + +S + S + SD + S + DS + Sbjct: 297 TAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGY 356 Query: 702 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSESDSDSDSDSDSDS 761 S + DS + S + SD + S + +DS + S + +S Sbjct: 357 GSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQ 416 Query: 762 DSDSDSDSDSESDSDSDSDSDSESDSDSDSDSDSDSASDSDSGSDSDSSSDSDSDSTSDT 821 + S ++ SD + S + DS + S +G DS ++ S T+ Sbjct: 417 TAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQK 476 Query: 822 GSDNDSDSDSNSDSESGSN 840 GSD + S S + S+ Sbjct: 477 GSDLTAGYGSTSTAGYESS 495 Score = 35.5 bits (81), Expect = 0.001 Identities = 59/290 (20%), Positives = 107/290 (36%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSA--SDSDSASDSDSASDS 609 G + +SD G S S + ++S +G ST + +S + S + SD Sbjct: 517 GSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDL 576 Query: 610 DSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 669 + S + SDS+ + S ++ S + S + S + S S + + Sbjct: 577 TAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGA 636 Query: 670 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 729 DS + S + +S + S + SD + S S + +DS + S Sbjct: 637 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQ 696 Query: 730 DSDSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDS 789 + +S + S ++ SD S S S + +DS + S + S + Sbjct: 697 TAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGY 756 Query: 790 DSDSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S + S +G S S++ +DS + GS + S + GS Sbjct: 757 GSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGS 806 Score = 35.1 bits (80), Expect = 0.002 Identities = 61/290 (21%), Positives = 106/290 (36%), Gaps = 2/290 (0%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSA--SDSDSASDSDSASDS 609 G + E SD G S + SDS +G ST + S+ + S + S Sbjct: 565 GSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVL 624 Query: 610 DSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 669 + S S + +DS+ + S + +S + S + SD + S S + + Sbjct: 625 TTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGA 684 Query: 670 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 729 DS + S + +S + S + SD S S S + +DS + S Sbjct: 685 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQ 744 Query: 730 DSDSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDS 789 + S + S + S + S S + +DS + S + S + Sbjct: 745 TASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGY 804 Query: 790 DSDSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S + SD +G S S++ +DS + GS + +S + GS Sbjct: 805 GSTQTAQERSDLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGS 854 Score = 33.6 bits (76), Expect = 0.004 Identities = 58/283 (20%), Positives = 112/283 (39%), Gaps = 4/283 (1%) Query: 561 SDSDPGSDSGSDSNSDSGSD--SGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSA 618 S + GS + + SD +G STS +G++S+ + S ++ +S + S Sbjct: 508 YGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGST 567 Query: 619 SDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSD 678 + SD + S + SDS+ + S ++ S + S + S + Sbjct: 568 QTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTG 627 Query: 679 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSA 738 S S + +DS + S + +S + S + SD + S S + +DS+ Sbjct: 628 YGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSS 687 Query: 739 SDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDSDSDSDSA 798 + S + +S + S + SD S S S + ++S + S ++ Sbjct: 688 LIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTAS 747 Query: 799 SDS--DSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 S +G S ++ S T+ GS + + +DS+ + GS Sbjct: 748 YHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGS 790 Score = 32.8 bits (74), Expect = 0.008 Identities = 56/284 (19%), Positives = 101/284 (35%), Gaps = 4/284 (1%) Query: 560 DSDSDPGSDSGSDSNSDSGSD--SGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDS 617 S + GS + S +G ST +G+DS + S + +S + S Sbjct: 171 THQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQMAGYGS 230 Query: 618 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDS 677 SD + S + DS+ + S + DS + S + SD + Sbjct: 231 TQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTA 290 Query: 678 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 737 S + +DS + S + +S + S + SD + S + DS Sbjct: 291 GYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDS 350 Query: 738 ASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDSDSDSDS 797 + + S + DS + S + SD + S + ++S + S + Sbjct: 351 SLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTA 410 Query: 798 ASDSD--SGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGS 839 +S +G S ++ SD T+ GS + DS+ + GS Sbjct: 411 GEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGS 454 Score = 32.4 bits (73), Expect = 0.009 Identities = 60/284 (21%), Positives = 110/284 (38%), Gaps = 4/284 (1%) Query: 561 SDSDPGSDSGSDSNSDSGSD--SGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSA 618 +S + GS + GSD +G ST +GSDS+ + S ++ S + S Sbjct: 556 YNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGST 615 Query: 619 SDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSD 678 + S + S S + +DS+ + S + +S + S + SD + Sbjct: 616 QTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAG 675 Query: 679 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSA 738 S S + +DS + S + +S + S + SD S S S + +DS+ Sbjct: 676 YGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSS 735 Query: 739 SDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDSDSDSDSA 798 + S + S + S + S + S S + ++S + S + Sbjct: 736 LIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAG 795 Query: 799 SDS--DSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGSN 840 S +G S ++ SD T+ GS + + +DS+ + GS Sbjct: 796 YHSILTAGYGSTQTAQERSDLTTGYGSTSTAGADSSLIAGYGST 839 Score = 31.6 bits (71), Expect = 0.016 Identities = 56/284 (19%), Positives = 103/284 (36%) Query: 561 SDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASD 620 S GSDS + S + S+ +G S + S + S S + +DS+ Sbjct: 582 STGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLI 641 Query: 621 SDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSD 680 + S + +S + S + SD + S S + +DS+ + S + + Sbjct: 642 AGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYN 701 Query: 681 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASD 740 S + S + SD S S S + +DS + S + S + S Sbjct: 702 SILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQT 761 Query: 741 SDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDSDSDSDSASD 800 + S + S S + +DS + S + S + S + SD + Sbjct: 762 AREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGYG 821 Query: 801 SDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGSNNNVV 844 S S + +DSS + ST G ++ + S + N+++ Sbjct: 822 STSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLT 865 Score = 31.3 bits (70), Expect = 0.025 Identities = 58/284 (20%), Positives = 106/284 (37%) Query: 561 SDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASD 620 S S G+DS + S +G +S +G S + SD + S S + +DS+ Sbjct: 630 STSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLI 689 Query: 621 SDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSD 680 + S + +S + S + SD S S S + +DS+ + S + Sbjct: 690 AGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYH 749 Query: 681 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASD 740 S + S + S + S S + +DS + S + S + S Sbjct: 750 SSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQT 809 Query: 741 SDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDSDSDSDSASD 800 + SD + S S + +DS + S + +S + S + +SD + Sbjct: 810 AQERSDLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYG 869 Query: 801 SDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESGSNNNVV 844 S S + DSS + ST G ++ + S + N+++ Sbjct: 870 STSTAGYDSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLT 913 Score = 30.9 bits (69), Expect = 0.032 Identities = 59/287 (20%), Positives = 103/287 (35%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDS 611 G + E S G S S + +DS +G ST +G +S + S + SD Sbjct: 613 GSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDL 672 Query: 612 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDS 671 + S S + + S + S + +S + S + SD S S S + + Sbjct: 673 TAGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGA 732 Query: 672 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 731 DS + S + S + S + S + S S + +DS + S Sbjct: 733 DSSLIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQ 792 Query: 732 DSDSDSASDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSESDSDSDS 791 + S + S + SD + S S + +DS + S + S + Sbjct: 793 TAGYHSILTAGYGSTQTAQERSDLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGY 852 Query: 792 DSDSDSASDSDSGSDSDSSSDSDSDSTSDTGSDNDSDSDSNSDSESG 838 S + +SD + S+S + DS+ G + + NS +G Sbjct: 853 GSTQTAQENSDLTTGYGSTSTAGYDSSLIAGYGSTQTAGYNSILTAG 899
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.8 bits (69), Expect = 0.016 Identities = 28/162 (17%), Positives = 52/162 (32%), Gaps = 4/162 (2%) Query: 261 ALKLKADTEAAKNDVSKRSKRSLNTQNNKST-TQEISEEQKAEYQRKSEALKERFINRQK 319 +KA+T+ + S + T K T T E E+ K E ++ E K Sbjct: 1073 KSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVT-SQVSP 1131 Query: 320 SKNESVVSLIDDEDDNENDRQLVVSAPSKKPTTPTTYTETTTQVPMPTVERQTQQQIVYK 379 + +S E END + + P + T + + + T+ V Sbjct: 1132 KQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNT 1191 Query: 380 TPKPLAGLNGESHDFTTTHQSPTTSNHTHNNVVEFEETSALP 421 + N E+ TT + + + ++P Sbjct: 1192 GNSVVE--NPENTTPATTQPTVNSESSNKPKNRHRRSVRSVP 1231
>PF05704#Capsular polysaccharide synthesis protein Length = 307 Score = 27.2 bits (60), Expect = 0.038 Identities = 13/69 (18%), Positives = 24/69 (34%), Gaps = 7/69 (10%) Query: 116 EWVKKNYENTNHRYLVTLNLNSK-------KFTYCTKIIYQAYKFGVSEKSVKSYGLHII 168 W + Y N + +++ N + + YK + +Y HI Sbjct: 239 YWKEIPYVNNVNPHMLQYLGNLPYDNSMFNYIKSTSPVQKLTYKLDYNNLKRNTYYDHIF 298 Query: 169 SPYAIKDNF 177 S +KDN+ Sbjct: 299 SIDKLKDNY 307
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 25.9 bits (56), Expect = 0.030 Identities = 10/29 (34%), Positives = 17/29 (58%) Query: 61 RIKESISYPVSHVLVNGIRYKIVDTRIYR 89 RI + PV + + G RY+I+D ++ R Sbjct: 22 RISQHWQNPVGELNIGGKRYRIIDNQVLR 50
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 52.8 bits (126), Expect = 7e-09 Identities = 39/189 (20%), Positives = 77/189 (40%), Gaps = 34/189 (17%) Query: 8 ATIEASVAKFKRQIDSAVKSVQRFKRVADQTKDVELNANDKKLQKTIKVAKKSLDAFSNK 67 T+EA A + + K+++ + +K + A + Sbjct: 249 KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADL-------E 301 Query: 68 NVKAKLDASIQDLQQKILESNFELDKLNSKEASPEVKLQKQKLT--KDIAEAEVK----- 120 + L+A+ Q L++ L++ S+EA +++ + QKL I+EA + Sbjct: 302 HQSQVLNANRQSLRRD-LDA--------SREAKKQLEAEHQKLEEQNKISEASRQSLRRD 352 Query: 121 --LSELEKKRISIDVNADNSKFNRVLKVSKASLEALNRS-----KAKAIIDVDNGVANSK 173 S KK+ + A++ K K+S+AS ++L R +AK ++ ANSK Sbjct: 353 LDASREAKKQ----LEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSK 408 Query: 174 IKRTKEELK 182 + ++ K Sbjct: 409 LAALEKLNK 417 Score = 43.5 bits (102), Expect = 5e-06 Identities = 29/129 (22%), Positives = 57/129 (44%), Gaps = 11/129 (8%) Query: 7 KATIEASVAKFKRQIDS---AVKSVQRFKRVADQTKDVELNANDKKLQK---TIKVAKKS 60 + A+ +R +D+ A K ++ + ++ + A+ + L++ + AKK Sbjct: 304 SQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKI-SEASRQSLRRDLDASREAKKQ 362 Query: 61 LDAFSNKNVKAK--LDASIQDLQQKILESNFELDKLNSKEASPEVKLQK-QKLTKDIAEA 117 L+A K + +AS Q L++ + S ++ KL +KL K++ E Sbjct: 363 LEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKEL-EE 421 Query: 118 EVKLSELEK 126 KL+E EK Sbjct: 422 SKKLTEKEK 430 Score = 33.5 bits (76), Expect = 0.006 Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 15/122 (12%) Query: 7 KATIEASVAKFK--RQI-DSAVKSVQRF---KRVADQTKDVELNANDKKLQKTIKV---- 56 K +EA K + +I +++ +S++R R A + + L + KL K+ Sbjct: 360 KKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKEL 419 Query: 57 -AKKSLDAFSNKNVKAKLDASIQDLQQKILESNFELDKLNSKEAS----PEVKLQKQKLT 111 K L ++AKL+A + L++K+ + EL KL + +AS P+ K + + Sbjct: 420 EESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVP 479 Query: 112 KD 113 Sbjct: 480 GK 481
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 29.1 bits (64), Expect = 0.040 Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 25/137 (18%) Query: 225 KDTD------IKAEPE-LLDKINIANVEGLENKLQEVEKIKDTTLNDSKTYTDSKIAELV 277 KDTD +K E E + N + E L N + + L + YTDSK AE + Sbjct: 204 KDTDAVNVAQLKKEIEKTQENTNKRSAELLANANAYADNKSSSVLGIANNYTDSKSAETL 263 Query: 278 DSAPESM----NTLRELAEAIQNNSISESVLQQIG--------SKVSTEDFEGFKQSLNS 325 ++A + + +A+A +NS++ + L+ + + T + K+S + Sbjct: 264 ENARKEAFAQSKDVLNMAKA-HSNSVARTTLETAEEHANSVARTTLETAEEHANKKSAEA 322 Query: 326 L-----YADKNHSHTIK 337 L YAD SHT+K Sbjct: 323 LASANVYADSKSSHTLK 339
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 36.2 bits (83), Expect = 7e-04 Identities = 17/143 (11%), Positives = 48/143 (33%), Gaps = 14/143 (9%) Query: 420 QLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQEKRAQLD 479 E+ +S + + Q + + ++EK + + + + + K+ Q + Sbjct: 1082 TNEVAQSGSETKE----TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSE 1137 Query: 480 ESRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEE 539 + E A+ N+ E Q + + ++ ++T + + VT+ Sbjct: 1138 TVQPQAEPARENDPTVNIKEPQ-------SQTNTTAD---TEQPAKETSSNVEQPVTEST 1187 Query: 540 IGDIVSQWTGIPVSKLVETEREK 562 + + P + T + Sbjct: 1188 TVNTGNSVVENPENTTPATTQPT 1210
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 228 bits (582), Expect = 2e-69 Identities = 120/451 (26%), Positives = 210/451 (46%), Gaps = 48/451 (10%) Query: 15 IISHPDAGKTTLTEKLLYFSGAIREAGTVKGKKTGKFATSDWMKVEQERGISVTSSVMQF 74 +++H DAGKTTLTE LLY SGAI E G+V T +D +E++RGI++ + + F Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTT----RTDNTLLERQRGITIQTGITSF 63 Query: 75 DYDDYKINILDTPGHEDFSEDTYRTLMAVDSAVMVIDCAKGIEPQTLKLFKVCKMRGIPI 134 +++ K+NI+DTPGH DF + YR+L +D A+++I G++ QT LF + GIP Sbjct: 64 QWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT 123 Query: 135 FTFINKLDRVGKEPFELLDEIEETLNIETYPMNWPIGMGQSFFGIIDRKSKTIEPFRDEE 194 FINK+D+ G + + +I+E L+ E +I +K + Sbjct: 124 IFFINKIDQNGIDLSTVYQDIKEKLSAEI---------------VIKQKVE------LYP 162 Query: 195 NILHLNDDFELEEDHAITNDSAF-EQAIEELMLVEEAGEAFDNDALLSGDLTPVFFGSAL 253 N+ N + D I + E+ + L E ++ + L PV+ GSA Sbjct: 163 NMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAK 222 Query: 254 ANFGVQNFLNAYVDFAPMPNARQTKEDVEVSPFDDSFSGFIFKIQANMDPKHRDRIAFMR 313 N G+ N + + R E G +FKI+ K R R+A++R Sbjct: 223 NNIGIDNLIEVITNKFYSSTHRGQSE----------LCGKVFKIE--YSEK-RQRLAYIR 269 Query: 314 VVSGAFERGMDVTLQRTNKKQKITRSTSFMADDKETVNHAVAGDIIGLYDTG---NYQIG 370 + SG V + K KIT + + + ++ A +G+I+ L + N +G Sbjct: 270 LYSGVLHLRDSVRISEKEKI-KITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLG 328 Query: 371 DTLVGGKQTYSFQDLPQFTPEIFMKVSAKNVMKQKHFHKGIEQLVQEG-AIQYYKTLHTN 429 DT + ++ LP + V +++ + ++ ++YY T+ Sbjct: 329 DTKLLPQRERIENPLPL----LQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATH 384 Query: 430 QIILGAVGQLQFEVFEHRMKNEYNVDVVMEP 460 +IIL +G++Q EV ++ +Y+V++ ++ Sbjct: 385 EIILSFLGKVQMEVTCALLQEKYHVEIEIKE 415
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 29.1 bits (65), Expect = 0.004 Identities = 9/53 (16%), Positives = 22/53 (41%), Gaps = 4/53 (7%) Query: 16 NLNNLLDKLHKALKERDEYKKQRDELIEDIAKLRERN----EELENMWRTVKN 64 + + LL+ + A + D K + +L + + R + L N + ++ Sbjct: 279 SSSKLLENFYYAKDKSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCED 331
>PF05272#Virulence-associated E family protein Length = 892 Score = 405 bits (1041), Expect = e-130 Identities = 135/433 (31%), Positives = 191/433 (44%), Gaps = 38/433 (8%) Query: 358 DAMQDFDEIVNSDDAWSETLEITSKGTFKASIPNIEIILRNDPNLKGKIAFNEFTKQIEC 417 D F E D L + + K + LR+ P L G +AF+E +Q Sbjct: 424 DGEDPFGE---WLDDEVARLRLRGRWLLKPRRAALIEALRSAPALAGCVAFDELREQPVA 480 Query: 418 LGKVPWNTNFKTRQWQDGDDSSLRSYIEKIYD-IHHSGKT-KDAIISVAMQNAYHPVRDY 475 + PW +D D L Y+E Y S +T + AI A N HP RD+ Sbjct: 481 VRAFPWRKA--PGPLEDADVLRLADYVETTYGTGEASAQTTEQAINVAADMNRVHPFRDW 538 Query: 476 LNKISWDGHKRLEKLFIKYLGVEDTEVN-------RTTTKKALTAGIARVMEPGCKFDYM 528 + WD RLEK + LG + + K L +ARVMEPGCKFDY Sbjct: 539 VKAQQWDEVPRLEKWLVHVLGKTPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYS 598 Query: 529 LTLYGPQGVGKSALLKKLGGA-WFSDSLVSV-TGKEAYEALQGVWLMEMAELAATRKAEV 586 + L G G+GKS L+ L G +FSD+ + TGK++YE + G+ E++E+ A R+A+ Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRRADA 658 Query: 587 EAIKHFISKQVDRFRVAYGHYIEDFPRQCIFIGTTNKVDFLRDETGGRRFWPMTVNPERV 646 EA+K F S + DR+R AYG Y++D PRQ + TTNK +L D TG RRFWP+ V P R Sbjct: 659 EAVKAFFSSRKDRYRGAYGRYVQDHPRQVVIWCTTNKRQYLFDITGNRRFWPVLV-PGRA 717 Query: 647 EVNWSKLTKDEIDQIWAEAKYYYEQGEELFLNPELEEAMRSIQSKHTEESPYTGIIDEYL 706 + W + + Q++AEA + Y GE F +PE EE + +E Sbjct: 718 NLVWLQKFR---GQLFAEALHLYLAGERYFPSPEDEEIYFRPE----QELRLVE------ 764 Query: 707 NTPIPSNWDDLTIFERRRFYQGDVDMLPTGNVDYVERNKVCALEVFVECFGKDKGDSRGS 766 L R G Y + V+ G D G S Sbjct: 765 ----TGVQGRLWALLTREGAPAAEGAAQKG---YSVNTTFVTIADLVQALGADPGKS-SP 816 Query: 767 MEIRKISNILRQL 779 M ++ + L + Sbjct: 817 MLEGQVRDWLNEN 829
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 34.3 bits (78), Expect = 8e-04 Identities = 27/121 (22%), Positives = 55/121 (45%), Gaps = 3/121 (2%) Query: 69 PLKMYEDYKVVNTEVSDLLTVSPNNSLSSFDFINQIETIRNEKGNAYVLIERD---IYHQ 125 PL +D++ + L T++ ++++S + + Q ++I N+ Y + ERD + H Sbjct: 194 PLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKNHPGYTIYERDSSIVTHD 253 Query: 126 PSKLFLLNPDVVEMLIENQSRELYYSIHAATGNKLIVHNMDMLHFKHIVASNMVQGISPI 185 + P E ++RE Y I+ +G ++N D++ K+ V + P Sbjct: 254 NDIFRTILPMDQEFTYRVKNREQAYRINKKSGLNEEINNTDLISEKYYVLKKGEKPYDPF 313 Query: 186 D 186 D Sbjct: 314 D 314
>INTIMIN#Intimin signature. Length = 939 Score = 30.8 bits (69), Expect = 0.002 Identities = 26/155 (16%), Positives = 55/155 (35%), Gaps = 23/155 (14%) Query: 1 MTKTLKVYKGDDVVASEQGEGKVSVTLSNLEADTTYPKGTYQVAWEENGKESSKV----- 55 +T T+KV KGD V++++ ++ + + T G +V S V Sbjct: 678 ITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVS 737 Query: 56 --------------DVPQFKTNPILVSGVSFTPETKSIMVNTDDNVEPNIAPSTATNKIL 101 I + G + ++ + ++ N Sbjct: 738 DVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYG----QVNLKASGGNGKY 793 Query: 102 KYTSEHPEFVTVDENTGAIHGVAEGTSVITAMSTD 136 + S +P +VD ++G + +GT+ I+ +S+D Sbjct: 794 TWRSANPAIASVDASSGQVTLKEKGTTTISVISSD 828
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 60.5 bits (146), Expect = 5e-11 Identities = 37/235 (15%), Positives = 76/235 (32%), Gaps = 11/235 (4%) Query: 72 YSQVEDELKQVNANYQKAKSSVKDVEKAYLKLVEANKKEKLALDKSKEALKSSNTELKKA 131 + + LK N++ ++KD + + K++ DKS S EL+ Sbjct: 62 FEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEAR 121 Query: 132 ENQYKRTNQRKQDAYQ----KLKQLRDAEQKLKNSNQATTAQLKRASDAVQKQSAKHKAL 187 + ++ + + K+K L + L L+ A + SAK K L Sbjct: 122 KADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTL 181 Query: 188 VEQYKQEGNQVQKLKVQNDNLSKSNDKIESSYAKTNTKLKQTEKEFNDLNNTIKNHSANV 247 + L+ + L K+ + + + K+K E E L + + Sbjct: 182 EAEK-------AALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKAL 234 Query: 248 AKAETAVNKEKAALNNLERSIDKASSEMKTFNKEQMIAQSHFGKLASQADVMSKK 302 A + A + LE + K A + +++ + + Sbjct: 235 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAE 289 Score = 58.2 bits (140), Expect = 3e-10 Identities = 33/239 (13%), Positives = 70/239 (29%), Gaps = 3/239 (1%) Query: 28 RQLGVVNSEMKANLSAFDKSEKSMEKYQARIKGLNDRLKVQKKMYSQVEDELKQVNANYQ 87 L + NS++ N A + + + K + + EL+ A+ + Sbjct: 67 NTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLE 126 Query: 88 KAKSSVKDVEKAYLKLVEANKKEKLALDKSKEALKSSNTELKKAENQYKRTNQRKQDAYQ 147 KA + K + L+ A N + + + Sbjct: 127 KAL---EGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEA 183 Query: 148 KLKQLRDAEQKLKNSNQATTAQLKRASDAVQKQSAKHKALVEQYKQEGNQVQKLKVQNDN 207 + L + +L+ + + S ++ A+ AL + ++ + Sbjct: 184 EKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTA 243 Query: 208 LSKSNDKIESSYAKTNTKLKQTEKEFNDLNNTIKNHSANVAKAETAVNKEKAALNNLER 266 S +E+ A + + EK N SA + E +A +LE Sbjct: 244 DSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEH 302 Score = 57.0 bits (137), Expect = 6e-10 Identities = 45/240 (18%), Positives = 90/240 (37%), Gaps = 14/240 (5%) Query: 11 ELKLDHLGVQEGMKGLKRQLGVVNSEMKANLSAFDKSEKSMEKYQARIKGLNDRLKVQKK 70 L+ + ++ L++ L + A+ + E AR L L+ Sbjct: 180 TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 239 Query: 71 MYSQVEDELKQVNANYQKAKSSVKDVEKAYLKLVEANKKEKLALDKSKEALKSSNTELKK 130 + ++K + A ++ ++EKA + + + + + + E Sbjct: 240 FSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKAD 299 Query: 131 AENQ-------YKRTNQRKQDAYQKLKQLRDAEQKLKNSNQATTAQLKR------ASDAV 177 E+Q + + + + KQL QKL+ N+ + A + AS Sbjct: 300 LEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREA 359 Query: 178 QKQS-AKHKALVEQYKQEGNQVQKLKVQNDNLSKSNDKIESSYAKTNTKLKQTEKEFNDL 236 +KQ A+H+ L EQ K Q L+ D ++ ++E + + N+KL EK +L Sbjct: 360 KKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKEL 419 Score = 51.2 bits (122), Expect = 4e-08 Identities = 41/261 (15%), Positives = 87/261 (33%), Gaps = 10/261 (3%) Query: 21 EGMKGLKRQLGVVNSEMKANLSAFDKSEKSMEKYQARIKGLNDRLKVQKKMYSQVEDELK 80 EG ++A +A + + +EK + + K + L Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224 Query: 81 QVNANYQKAKSSVKDVEKAYLKLVEANKKEKLALDKSKEALKSSNTELKKAENQYKRTNQ 140 A+ +KA + A ++ + EK AL+ + L+ + + Sbjct: 225 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIK 284 Query: 141 RKQDAYQKLKQLRDAEQKLKNSNQATTAQLKRASDAVQKQSAKHKALVEQYKQEGNQVQK 200 + L+ + L++ +Q A + + K L ++ QK Sbjct: 285 TLEAEKAALEAE---KADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEH-------QK 334 Query: 201 LKVQNDNLSKSNDKIESSYAKTNTKLKQTEKEFNDLNNTIKNHSANVAKAETAVNKEKAA 260 L+ QN S + + KQ E E L K A+ ++ + A Sbjct: 335 LEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREA 394 Query: 261 LNNLERSIDKASSEMKTFNKE 281 +E+++++A+S++ K Sbjct: 395 KKQVEKALEEANSKLAALEKL 415 Score = 35.4 bits (81), Expect = 0.003 Identities = 40/262 (15%), Positives = 92/262 (35%), Gaps = 14/262 (5%) Query: 905 KGVSKETEKALEKYVHYSEENSRIMEKVRLNSGQISEDKAKKLLKIETDL-----SNNLI 959 K LE E +EK + S + K+ +E + + Sbjct: 171 STADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL 230 Query: 960 AEIEKRNKKELEKTQELIDKYSAF--DEQEKQNILTRTKEKNDLRIKKEQELNQKIKELK 1017 + + I A + +Q L + E + + ++ K Sbjct: 231 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 290 Query: 1018 EKSLSDGQISENERKEIEK-LENQRRDITVKELSKTEKEQERILVRMQRNRNAYSIDEAS 1076 ++ E++ + + ++ RRD+ +K + E E + Q + S Sbjct: 291 AALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLR 350 Query: 1077 KAIKEAEKARKARKKEVDKQYEDDVIAIKNNVNLSKSEKDKLLAIADQRHKDEVRKAKSK 1136 + + + +A+K + E K E + I+ + +L + A K +V KA + Sbjct: 351 RDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREA------KKQVEKALEE 404 Query: 1137 KDAVVDVVKKQNKDIDKEMDLS 1158 ++ + ++K NK++++ L+ Sbjct: 405 ANSKLAALEKLNKELEESKKLT 426
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 219 bits (560), Expect = 1e-76 Identities = 77/155 (49%), Positives = 112/155 (72%) Query: 5 IAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKNSKKEGTFSLEERMDLIEQSVKHLP 64 A+ PGSFDPIT+GHLDIIER FD+++V VL+N K+ FS++ER++ I +++ HLP Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 65 NVKVHQFSGLLVDYCEQVGAKTIIRGLRAVSDFEYELRLTSMNKKLNNEIETLYMMSSTN 124 N +V F GL V+Y Q A I+RGLR +SDFE EL++ + NK L +++ET+++ +ST Sbjct: 62 NAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTE 121 Query: 125 YSFISSSIVKEVAAYRADISEFVPPYVEKALKKKF 159 YSF+SSS+VKEVA + ++ FVP +V AL +F Sbjct: 122 YSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQF 156
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.8 bits (82), Expect = 6e-04 Identities = 37/194 (19%), Positives = 71/194 (36%), Gaps = 15/194 (7%) Query: 447 RIVDKEAFTKANTDKSNKKEQQDNSAKKEA---------TPATPSKPTPSPVEKESQKQD 497 + VD T N +++ N+ + PATPS+ T + E Q+ Sbjct: 990 QTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESK 1049 Query: 498 SQKDDNKQLPSVEKENDASSESGKDKTPATKPT------KGEVESSSTTPTKVVSTTQNV 551 + + + + +N ++ K A T E + + TT TK +T + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 552 AKPTTASSKTTKDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSQNNKNTQENKAKSLP 611 K + KT + TS S + + S +Q + T + +Q N Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTE 1169 Query: 612 QTGEESNKDMTLPL 625 Q +E++ ++ P+ Sbjct: 1170 QPAKETSSNVEQPV 1183 Score = 30.0 bits (67), Expect = 0.035 Identities = 27/156 (17%), Positives = 45/156 (28%), Gaps = 5/156 (3%) Query: 37 EAQAAAEETGGTNTEAQPKTEAVASPTTTSEKAPET-KPVANAVSVSNKEVEAPTSETKE 95 A EE TE + V S + ++ ET +P A ++ V +++ Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQT 1162 Query: 96 AKEVKEVKAPKETKAVKPAAKATNNTYPILNQELREAIKNPAIKDKDHSAPNSRPIDFEM 155 + KET + + T N + NP + P Sbjct: 1163 NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVE----NPENTTPATTQPTVNSESSNK 1218 Query: 156 KKENGEQQFYHYASSVKPARVIFTDSKPEIELGLQS 191 K + +V+PA D L S Sbjct: 1219 PKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTS 1254
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.9 bits (77), Expect = 0.001 Identities = 27/132 (20%), Positives = 44/132 (33%), Gaps = 4/132 (3%) Query: 184 ADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVSTDTT 243 + A+ + P PA P TE + K + + +V + Sbjct: 1015 EEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKS 1074 Query: 244 KDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNET 303 + TQT + AQ+ E + QT + V K+Q+ KVT + Sbjct: 1075 NVKANTQTN---EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTS-QVS 1130 Query: 304 PKQASKAKELPK 315 PKQ P+ Sbjct: 1131 PKQEQSETVQPQ 1142
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.5 bits (68), Expect = 0.027 Identities = 22/127 (17%), Positives = 47/127 (37%), Gaps = 13/127 (10%) Query: 378 DFSQHGGNRLGANSLLSAIYGGTVAGPNAIDYISNIDRSYTDMDESIFEKRKAEEQERFD 437 + ++G N N++ + + G + I D T+ F R ER + Sbjct: 246 NIDKYGSNYSKGNAVFNLMKGIDYYTNSVIYNTKGYDAKNTE-----FYNRIDPYMERLE 300 Query: 438 KLLAMR---GTENAYKLHRELGEIMTANVTVVRENEKLLETDKKIVELMKRYEDIDMEDT 494 L + +NA+ ++ L T + RE+ + + + + MK Y + + Sbjct: 301 SLCTIGDKLNNDNAWLVNNALYY--TGRMGKFREDPSISQ--RALERAMKEYPYLSYQYI 356 Query: 495 QTWSNQA 501 + +N Sbjct: 357 E-AANDL 362
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 313 bits (803), Expect = e-109 Identities = 72/318 (22%), Positives = 144/318 (45%), Gaps = 24/318 (7%) Query: 9 VTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKEN--GMHKKVFY 66 +TTTL + L+ P+AN + T DIG + ++ N G+ + + + Sbjct: 7 LTTTLSVS--LLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQF 64 Query: 67 SFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKS-GLAWPSAFKVQLQLPDNEVAQIS 125 F+ DK +NK L+++ +G I+ + Y+ + N + WP + + L+ D V+ I Sbjct: 65 DFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLI- 123 Query: 126 DYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILES 185 +Y P+N I++ TL Y GN + +GG N S ++ Y Q ++ + +E Sbjct: 124 NYLPKNKIESTNVSQTLGYNIGGNFQSAPS--LGGNGSFNYS--KSISYTQQNYVSEVEQ 179 Query: 186 PTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPNKASSL 245 K V W V N+ ++ + + LF+ + S + F+ ++ L Sbjct: 180 QNSKSVLWGVKANSFATESG-------QKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPL 232 Query: 246 LSSGFSPDFATVITMDRKASKQQTNIDVIYERVRD-----DYQLHWTSTNWKGTNTKDKW 300 + SGF+P F ++ + K S + ++ Y R D H+ ++ G + + Sbjct: 233 VQSGFNPSFIATVSHE-KGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAF 291 Query: 301 TDRS-SERYKIDWEKEEM 317 +R+ + +Y+++W+ E+ Sbjct: 292 VNRNYTVKYEVNWKTHEI 309
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 49.7 bits (118), Expect = 2e-09 Identities = 53/223 (23%), Positives = 89/223 (39%), Gaps = 12/223 (5%) Query: 1 MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHF 60 M+K + N + + LLL T P+ S A + D NI +L+ +Y+ Sbjct: 1 MNKKLLMNFFIVSPLLLATTATDFTPVPLSSNQIIKTAKASTND--NIKDLLDWYSSGSD 58 Query: 61 SFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKD-KDTDQ 119 +F+N DN + +K S + ++ + + + K VD+ + K Sbjct: 59 TFTN--SEVLDNSLGSMRIKNTDGSISLIIFPSP-YYSPAFTKGEKVDLNTKRTKKSQHT 115 Query: 120 LWWSYRETFTGGVTPAAK-PSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFR 178 +Y GVT K P+ L V+ K + K +K L + +DF Sbjct: 116 SEGTYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYGPKF---DKKQLAISTLDFE 172 Query: 179 AREALIKNKILY-TENRNKGKLKIT-GGGNNYTIDLSKRLHSD 219 R L + LY + ++ G KIT G+ Y DLSK+ + Sbjct: 173 IRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYN 215
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 56.6 bits (136), Expect = 7e-12 Identities = 55/228 (24%), Positives = 91/228 (39%), Gaps = 15/228 (6%) Query: 16 LLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTI 75 LLL T T F P++S+ K + N+ N+ +L +YS TF+NS + G++ Sbjct: 15 LLLATTATDFTPVPLSSNQIIKTAKASTND-NIKDLLDWYSSGSDTFTNSEVLDNSLGSM 73 Query: 76 HATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGI---KDQETIDSFALSQETFTGGV 132 ++ + S + P + + + + VD+ K Q T + + + GV Sbjct: 74 R---IKNTDGSISLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQI--SGV 128 Query: 133 TPA-ATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYN 191 T L V K + + + +K L + LDF IR L + LY Sbjct: 129 TNTEKLPTPIELPLKV--KVHGKDSPLKYG-PKFDKKQLAISTLDFEIRHQLTQIHGLYR 185 Query: 192 NSYNKGQI-KITGTDNN-YTIDLSKRLPSTDANRYVKKPQNAKIEVIL 237 +S G KIT D + Y DLSK+ + + IE + Sbjct: 186 SSDKTGGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 61.6 bits (149), Expect = 1e-13 Identities = 62/222 (27%), Positives = 96/222 (43%), Gaps = 17/222 (7%) Query: 2 KKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFS 61 KK +MN ++S LLL TT+T P+S + K S N+ NI +L+ +Y+ + Sbjct: 3 KKLLMNFFIVSP--LLLATTATDFTPVPLSSNQIIKTAKASTND-NIKDLLDWYSSGSDT 59 Query: 62 LSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGT---KDEDTV 118 + + GS+ ++ + +F S + + + + VD+ K + T Sbjct: 60 FTNSEVLDNSLGSMR--IKNTDGSISLIIFPSP-YYSPAFTKGEKVDLNTKRTKKSQHTS 116 Query: 119 EGYWTYDETFTGGVTPA-ATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDF 177 EG TY GVT + L +K K + G +F +K L + LDF Sbjct: 117 EG--TYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYGPKF---DKKQLAISTLDF 171 Query: 178 RIRQTLIKNKKLYNGEFNKGQI-KIT-ADGNNYTIDLSKKLK 217 IR L + LY G KIT DG+ Y DLSKK + Sbjct: 172 EIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFE 213
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 389 bits (1001), Expect = e-139 Identities = 145/314 (46%), Positives = 211/314 (67%), Gaps = 7/314 (2%) Query: 1 MMAKIVVALGGNALGK-----SPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSI 55 M ++V+ALGGNAL + S +E ++ V+ TA+ + +I +G+E+VI+HGNGPQVGS+ Sbjct: 1 MGKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSL 60 Query: 56 NLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVD 115 L ++ PA P GAMSQ +IGY +Q++L+NEL GM+K+VVT++TQ VD Sbjct: 61 LLHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVD 120 Query: 116 ENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIK 175 +NDPAF NP+KP+G FY++E A+++ +EKG+I ED+GRG+RRVVPSP P +E E+IK Sbjct: 121 KNDPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIK 180 Query: 176 TLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDY 235 L++ +VIA+GGGG+PVI E KG++AVIDKD L + D +ILT ++ Sbjct: 181 KLVERGVIVIASGGGGVPVILE-DGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNG 239 Query: 236 VYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLN 295 + + TE +Q L+ V+EL++Y +E F GSM PK+ AAI FIE + ++ I L Sbjct: 240 AALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAI-IAHLE 298 Query: 296 ELDAALEGKVGTVI 309 + ALEGK GT + Sbjct: 299 KAVEALEGKTGTQV 312
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 29.1 bits (65), Expect = 0.016 Identities = 11/34 (32%), Positives = 15/34 (44%) Query: 167 IVTIGLAVLGGLWFPINTFPNWLQHVAHVLPSYH 200 +V + L G FP++ P Q A LP H Sbjct: 184 LVITPILFLSGAVFPVDQLPIVFQTAARFLPLSH 217
>PF04647#Accessory gene regulator B Length = 212 Score = 32.8 bits (75), Expect = 0.001 Identities = 18/112 (16%), Positives = 42/112 (37%), Gaps = 9/112 (8%) Query: 35 WLYIISVIVFSLSYLILVIVNNRLNTLMFYILLIIHYFIICYFVFSVHPMLSLFFFYSAF 94 + S++VF++ I +++ L+ I I + + V +P Sbjct: 79 RCTLTSLLVFNVLAYIAHLIDPAYFQLLILIAFITSLLALLFLVPVDNP---------RN 129 Query: 95 AVPFTFKNNVKKTATNLFILTMIICTIITYLLYNNYFVAMMVYYVVISLIML 146 + T + K T++ ++ + +I Y LY + ++ V+ L Sbjct: 130 LISNTEQRKTLKLKTSMVLMVLFGGSIGAYRLYTHQIALAILLGVLWQTFTL 181
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.2 bits (151), Expect = 9e-14 Identities = 23/116 (19%), Positives = 53/116 (45%), Gaps = 2/116 (1%) Query: 2 TSLIIAEDQNMLRQAMVQLIKLHGDFEILADTDNGLDAMKLIEEYNPNVVILDIEMPGMT 61 ++++A+D +R + Q + G +++ T N + I + ++V+ D+ MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRAG-YDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLEVLAEIRKKHLNIKVIIVTTFKRPGYFEKAVVNDVDAYVLKERSIEELVETINK 117 ++L I+K ++ V++++ KA Y+ K + EL+ I + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 29.7 bits (66), Expect = 0.041 Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 5/58 (8%) Query: 296 QNTMLKRANEDESQ-----WNSLLEKYAETYPELAEEFKLAISGKLPKNYKDELPRFE 348 QN +L +D + +L EKY E Y ++A+E GK N + L FE Sbjct: 337 QNNLLNSQIKDAVDATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFE 394
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 33.7 bits (77), Expect = 0.005 Identities = 39/249 (15%), Positives = 83/249 (33%), Gaps = 4/249 (1%) Query: 241 LQARSKEILAFVNESKETAIKEYEIIEKKTLENNILKDNINQLNKNKIDFVQLKEQQPEI 300 I F E+ + + + +L N ID ++ Sbjct: 174 FDFSYDMIENFTKENSLQLNDNIFSKIFTGVSKTLSSEICFRLKNNSIDLSLSNLKEIVE 233 Query: 301 DEIEAKLKLLQDITNLLNYIENREKIETKIAN--SKKDISKTNNKILNLDCDKRNIDKEK 358 + ++ + Y +N + N SK+D K + + K+K Sbjct: 234 VCKDLFKEIQSNKFEFNCYTKNNSFVGFYCLNLMSKEDYKKIQYDSSSKLLENFYYAKDK 293 Query: 359 K--MLEENGDLIESKTSFIDKTRVLFNDINKYQQSYLNIECLITEGEQLGDELNNLIKGL 416 + ++ DL + + I++ +N + + + GE L + L KGL Sbjct: 294 SDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTANIYALKKGL 353 Query: 417 EKVEDSIGNNESDYEKIIELNNAITNINNEINIIKENEKAKAELDKLLGSKQELENQINE 476 +E + +E+ I L+ T N + K+ K K + + E ++N Sbjct: 354 SHIELANYYSENYDTVKITLDENKTPSQNVQSYYKKYNKLKKSEEAANEQLLQNEEELNY 413 Query: 477 ETTIMKNLE 485 +++ N+ Sbjct: 414 LYSVLTNIN 422
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 145 bits (367), Expect = 2e-48 Identities = 62/131 (47%), Positives = 90/131 (68%), Gaps = 11/131 (8%) Query: 1 MLKEFKEFALKGNVLDLAIAVVMGAAFNKIISSLVENIIMPLIGKIFGSVDFAK------ 54 ++KEF+EFA++GNV+DLA+ V++GAAF KI+SSLV +IIMP +G + G +DF + Sbjct: 3 IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62 Query: 55 ----EWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTL-MKKEEAEEEAVVEENVVLL 109 + + YG+FIQ+V DF+I+AFA+F+ +K+ N L KKEE + VLL Sbjct: 63 DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122 Query: 110 TEIRDLLREKK 120 TEIRDLL+E+ Sbjct: 123 TEIRDLLKEQN 133
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 45.4 bits (107), Expect = 1e-05 Identities = 49/323 (15%), Positives = 96/323 (29%), Gaps = 9/323 (2%) Query: 2582 TKVRAAQTKIDQAKALLQNKEDNSQLVTSKNNLQSSVNQVPSTAGMTQQSIDN------- 2634 T +A Q L + +E + N L+ + + + D Sbjct: 37 TNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSN 96 Query: 2635 YNAKKREAETEITAAQRVIDNGDATAQQISDEKHRVDNALTALNQAKHDLTADTHALEQA 2694 K R+ + ++ I +A + N TA + L A+ AL Sbjct: 97 AKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAAR 156 Query: 2695 VQQLNRTGTTTGKKPASITAYNNSIRALQSDLTSAKNSANAIIQKPIRTVQEVQSALTNV 2754 L + + +A ++ A ++ L + + ++ + + + + Sbjct: 157 KADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTL 216 Query: 2755 NRVNERLTQAINQLVPLADNSALRTAKTKLDEEINKSVTTDGMTQSSIQAYENAKRAGQT 2814 L L T +I ++ E A Sbjct: 217 EAEKAALAARKADL--EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN 274 Query: 2815 ETTNAQNVINNGDATDQQIAAEKTKVEEKYNSLKQAIAGLTPDLAPLQTAKTQLQNDIDQ 2874 +T I +A + AEK +E + L L DL + AK QL+ + + Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQK 334 Query: 2875 PTSTTGMTSASVAAFNDKLSAAR 2897 ++ AS + L A+R Sbjct: 335 LEEQNKISEASRQSLRRDLDASR 357 Score = 41.2 bits (96), Expect = 2e-04 Identities = 56/339 (16%), Positives = 103/339 (30%), Gaps = 24/339 (7%) Query: 2732 SANAIIQKPIRTVQEVQSALTNVNRVNERLTQAINQLVPLAD-----NSALRTAKTKLDE 2786 + + T+++VQ N L + L N L + E Sbjct: 40 VSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKE 99 Query: 2787 EINKSVTTDGMTQSSIQAYENAKRAGQTETTNAQNVINNGDATDQQIAAEKTKVEEKYNS 2846 ++ K+ + S IQ E K + A N A + + AEK + + Sbjct: 100 KLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKAD 159 Query: 2847 LKQAIAGLTPDLAPLQTAKTQLQNDIDQPTSTTGMTSASVAAFNDKLSAARTKIQEIDRV 2906 L++A+ G L+ + A A L A + Sbjct: 160 LEKALEGAMNFSTADSAKIKTLEAEKAA-------LEARQAELEKALEGAM------NFS 206 Query: 2907 LASHPDVATIRQNVTAANAAKTALDQARNGLTVDKAPLENAKNQLQHSIDTQTSTTGMTQ 2966 A + T+ A A K L++A G L+ + + Sbjct: 207 TADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELE 266 Query: 2967 DSINAYNAKLTAARNKVQQINQVLAGSPTVDQINTNTSAANQAKSDLDHARQALTPDKAP 3026 ++ TA K++ + + + L+ RQ+L D Sbjct: 267 KALEGAMNFSTADSAKIKTLEA------EKAALEAEKADLEHQSQVLNANRQSLRRDLDA 320 Query: 3027 LQNAKTQLEQSINQPTDTTGMTTASLNAYNQKLQAARQK 3065 + AK QLE + + ++ AS + + L A+R+ Sbjct: 321 SREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREA 359 Score = 38.1 bits (88), Expect = 0.002 Identities = 46/342 (13%), Positives = 103/342 (30%), Gaps = 28/342 (8%) Query: 9668 KLKEIEASNATDQDKLIAKNKAEELANSIINNINKA---TSNQAVSQVQTAGNHAIEQVH 9724 K++E + + L KN N + + N + A +++ E+ Sbjct: 54 KVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKAS 113 Query: 9725 ANEIPKAKIDANKDVDKQVQALIDEIDRNPNLTDKEKQALKDRINQILQQGHNDINNALT 9784 + +A+ + + + EK AL R L++ N T Sbjct: 114 KIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAAR-KADLEKALEGAMNFST 172 Query: 9785 K--EEIEQAKAQLAQALQDIKDLVKAKEDAKQDVDKQVQALIDEIDQNPNLTDKEKQALK 9842 +I+ +A+ A +L KA E A + + L ++ K Sbjct: 173 ADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEK 232 Query: 9843 DRINQILQQGHNGINNAMTKEEIEQAKAQLAQALKEIKDLVKAKENAKQDVDKQVQALID 9902 + + + E +A+ A+ K ++ + + ++A Sbjct: 233 ALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKT-LEAEKA 291 Query: 9903 EIDQNPNLTDKEKQALKDRINQILQQGHNDINNAMTKEEIEQAKAQLAQALQDIKDLVKA 9962 ++ + + Q L + + L + + K L Sbjct: 292 ALEAEKADLEHQSQVL--------------------NANRQSLRRDLDASREAKKQLEAE 331 Query: 9963 KEDAKNAIKALANAKRDQINSNPDLTPEQKAKALKEIDEAEK 10004 + + K + A R + + D + E K + E + E+ Sbjct: 332 HQKLEEQNKI-SEASRQSLRRDLDASREAKKQLEAEHQKLEE 372
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 40.3 bits (94), Expect = 5e-07 Identities = 14/79 (17%), Positives = 38/79 (48%), Gaps = 4/79 (5%) Query: 5 KQSAFTMIEMLVVMMLISIFLLLTMTSKGLSNLRVIDDEA-NIISFITELNYIKSQAIAN 63 +Q FT++EM+++++L+ + + + + S D A + F +L +++ + + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPAS---RDDSAAQTLARFEAQLRFVQQRGLQT 58 Query: 64 QGYINVRFYENSDTIKVIE 82 + V + + V+E Sbjct: 59 GQFFGVSVHPDRWQFLVLE 77
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 46.4 bits (110), Expect = 9e-10 Identities = 19/76 (25%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Query: 3 KFLKKTQAFTLIEMLLVLLIISLLLILIIPNI--AKQTAHIQSTGCNAQVKMVNSQIEAY 60 + K + FTL+E+++V++II +L L++PN+ K+ A Q + + + + ++ Y Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKA--VSDIVALENALDMY 59 Query: 61 ALKHNRNPSSIEDLIA 76 L ++ P++ + L + Sbjct: 60 KLDNHHYPTTNQGLES 75
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 84.1 bits (208), Expect = 4e-20 Identities = 65/347 (18%), Positives = 137/347 (39%), Gaps = 6/347 (1%) Query: 14 KKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKN-KQLGTTILSEISNGAPC 72 +K +LS + L L L+ L ++ + Q + QL + S++ G Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 73 NQIL-SLIGYSDTI-VMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILV 130 + G + + V E G++ VL +Y + ++ R+ + + YP +L Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 131 SIFIAMIIILNLTVIPQFQQLYTSMNIQLSSFQKTLSFFITSLPTIIVVMLIIVSMLAII 190 + IA++ IL V+P+ + + M L + L ++ T ML+ + + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 191 MKLIYNNLNMLNKIN-FVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQSIVDVYINH 249 +++ + ++ LPLI + T L + + + L + + + Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 250 SS-DPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQ 308 S D R L E G L + LE+ F P + + GE+ G+L+ L+ + Sbjct: 301 MSNDYARHRLSLATDAVRE-GVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAAD 359 Query: 309 ILVKQIEDKAIKQTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSI 355 ++ + +P+L + + ++ I L I+ P+ Q+ + Sbjct: 360 NQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 27.5 bits (61), Expect = 0.039 Identities = 20/99 (20%), Positives = 38/99 (38%), Gaps = 11/99 (11%) Query: 82 DFLKDPVKNGADKFKQYGLPIITSKVTPEK-------LNEGSTEIE-GFKFNVLHTPGHS 133 F+ + K + K Y +P++ S + + N I ++ G+ Sbjct: 39 VFISNLRKALPYERKLYDIPLLRSTLPGSQRYALIHLTNYADETISVAIDVTNVYVMGYR 98 Query: 134 PGSLTYVFDEFAVVG--DTLFNNGIGRTDL-YKGDYETL 169 G +Y F+E + +F + + L Y G+YE L Sbjct: 99 AGDTSYFFNEASATEAAKYVFKDAKRKVTLPYSGNYERL 137
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 184 bits (468), Expect = 2e-52 Identities = 106/439 (24%), Positives = 184/439 (41%), Gaps = 89/439 (20%) Query: 12 NIRNFSIIAHIDHGKSTLADRILEN---TKSVETRDMQDQLLDSMDLERERGITIKLNAV 68 I N ++AH+D GK+TL + +L N + + D D+ LER+RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 RLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLA 128 ++E N +IDTPGH+DF EV RSL+ +GAIL++ A G++AQT + Sbjct: 62 SFQWENTKVN-----IIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 129 LDNELELLPVINKIDLPAAEPERV--------------KQEIE--------DMIGLDQDD 166 + + INKID + V KQ++E + +Q D Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 167 VVLA---------------------------------------SAKSNIGIEEILEKIVE 187 V+ SAK+NIGI+ ++E I Sbjct: 177 TVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITN 236 Query: 188 VVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVG 247 + ++ L +F EY R ++ IR+ GV+ D +R+ K ++TE Sbjct: 237 KFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-KITE-- 293 Query: 248 INTPKQ---LPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMV 304 + T +D+ G++ + ++ +GDT L P E ++ P++ Sbjct: 294 MYTSINGELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLL---PQRERIENPL---PLL 346 Query: 305 YCGLFPIDNKNYNDLREALEKLQLNDASLEFE--PESSQALGFGYRTGFLGMLHMEIIQE 362 + P + L +AL ++ +D L + + + + FLG + ME+ Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEII-----LSFLGKVQMEVTCA 401 Query: 363 RIEREFGIELIATAPSVIY 381 ++ ++ +E+ P+VIY Sbjct: 402 LLQEKYHVEIEIKEPTVIY 420 Score = 35.6 bits (82), Expect = 6e-04 Identities = 12/75 (16%), Positives = 28/75 (37%), Gaps = 2/75 (2%) Query: 408 IFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQ 467 + EPY+ + P +Y+ + ++ ++ V + E+P + ++ Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNE-VILSGEIPARC-IQEYRSD 592 Query: 468 LKSNTKGYASFDYEF 482 L T G + E Sbjct: 593 LTFFTNGRSVCLTEL 607
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.1 bits (62), Expect = 0.034 Identities = 33/190 (17%), Positives = 71/190 (37%), Gaps = 27/190 (14%) Query: 37 QDDYTSRNFENKDTALKQSTSE---------NNSLSKLEDVQVKDGDNSKNKGPVYVDVK 87 +DD+ +RNF+ + + S ++++ QV G + + V D Sbjct: 733 EDDWINRNFKATTMNVTGNASLYSGRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYT 792 Query: 88 GAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQ 147 G V D+ ++ + L +V+ + + + +F + + N + + Sbjct: 793 GYV---TCTTDKLSDKALNSFNPTNL--RGNVNLTESANFVLGKANLFGTIQSRGNSQVR 847 Query: 148 IEVNS-------VHVKNGNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQ 200 + NS V + N ++LN+A S +V N++ + G+F Sbjct: 848 LTENSHWHLTGNSDVHQLDLANGHIHLNSADNSN--NVTKYNTLTVNSL----SGNGSFY 901 Query: 201 EIDDLKKVKG 210 + DL +G Sbjct: 902 YLTDLSNKQG 911
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.4 bits (94), Expect = 1e-05 Identities = 38/263 (14%), Positives = 95/263 (36%), Gaps = 22/263 (8%) Query: 52 QKADDLKVKEQELSQKFEERKTQLEETVAYTKERVEGFLNKSKNEQAALKAQQAAIKEEA 111 Q++ ++ EQ+ ++ + + +E + K + +++ + Q KE A Sbjct: 1046 QESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT-NEVAQSGSETKETQTTETKETA 1104 Query: 112 SANNLSDTSQEAQEIQEAKREAQAEADKSVAVSNEESKASALKVQQAAIKEEASANNLSD 171 + E + +A+ E +K+ V S+ S + Q ++ +A +D Sbjct: 1105 T--------------VEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREND 1150 Query: 172 TSQEAQEIQEAKKEAQAETDKSAAVSNEEPKAVALKAQQAAIKEEASANNLSDTSQEAQE 231 + +E Q ++ A+T++ A ++ + ++ N + T Q Sbjct: 1151 PTVNIKEPQ-SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQP 1209 Query: 232 VQEAKKEAQAEKDSDTSTKDASAAKVEVSKPESQAERLANAAKQKQAKLTPGSKESQLTE 291 +E + + + + E + + LT + + L++ Sbjct: 1210 ------TVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSD 1263 Query: 292 ALFAEKPVAKNDLKEIPQLVTKK 314 A + VA N K + Q +++ Sbjct: 1264 ARAKAQFVALNVGKAVSQHISQL 1286 Score = 38.1 bits (88), Expect = 8e-05 Identities = 47/332 (14%), Positives = 97/332 (29%), Gaps = 17/332 (5%) Query: 101 KAQQAAIKEEASANNLSDTSQEAQEIQEAKREAQAEADKSVAVSNEESKASALKVQQAAI 160 K Q + N + + EA S+ + + + Sbjct: 987 KRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQ 1046 Query: 161 KEEASANNLSDTSQEAQEIQEAKKEAQAET-DKSAAVSNEEPKAVALKAQQAAIKEEASA 219 + + N D ++ + +E KEA++ + + + + Q KE A Sbjct: 1047 ESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETA-- 1104 Query: 220 NNLSDTSQEAQEVQEAKKEAQAEKDSDTSTKDASAAKVEVSKPESQAERLANAAKQKQAK 279 + E +E + + E E TS + E +P+++ R + + Sbjct: 1105 ------TVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 280 LTPGSKESQLTEALFAEKPVAKNDLKEIPQLVTKKNDVSETETVNIDNKDTVKQKEAKFE 339 + + + TE E V N V E N T ++ Sbjct: 1159 QSQTNTTAD-TEQPAKETSSNVEQPVTESTTVNTGNSVVEN-PENTTPATTQPTVNSESS 1216 Query: 340 NGVITRKADEKTTNNTAVDKKSGKQSKKTTPSNKRNASKASTNKTSGQKKQHNKKSSQGA 399 N R + V+ + + ++T + S + S + ++ Sbjct: 1217 NKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLS------DARAKAQF 1270 Query: 400 KKQSSSSKLTQKNNQTSNKNSKTTNAKSSNAS 431 + ++Q +Q N N SN S Sbjct: 1271 VALNVGKAVSQHISQLEMNNEGQYNVWVSNTS 1302 Score = 36.6 bits (84), Expect = 2e-04 Identities = 36/222 (16%), Positives = 72/222 (32%), Gaps = 3/222 (1%) Query: 72 KTQLEETVAYTKERVEGFLNKSKNEQAALKAQQAAIKEEASANNLSD-TSQEAQEIQEAK 130 + EE + V + +E A+ + + + N D T AQ + AK Sbjct: 1011 PSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAK 1070 Query: 131 REAQAEADKSVAVSNEESKASALKVQQAAIKEEASANNLSDTSQEAQEIQEAKKEAQAET 190 + +S + + Q KE A+ E ++ QE K + Sbjct: 1071 EAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVS 1130 Query: 191 DKSAAVSNEEPKAVALKAQQAA--IKEEASANNLSDTSQEAQEVQEAKKEAQAEKDSDTS 248 K +P+A + IKE S N + +++ + + E + + + Sbjct: 1131 PKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVN 1190 Query: 249 TKDASAAKVEVSKPESQAERLANAAKQKQAKLTPGSKESQLT 290 T ++ E + P + + + + K S S Sbjct: 1191 TGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPH 1232
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 36.2 bits (83), Expect = 0.002 Identities = 48/321 (14%), Positives = 89/321 (27%), Gaps = 18/321 (5%) Query: 1323 QNQTNDQVDTTTNQAVNAIDNVEAEVVIKPTAIADIEKAVKEKQQQIDNSLDSTDNEKEV 1382 + N VDTT N I V IA +++A S + + Sbjct: 985 VEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENS 1044 Query: 1383 ASQALAKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKINQKANEL 1442 ++ EK + A AQ +A + K E + Sbjct: 1045 KQESKTVEKNEQDATETTAQNREVAKEA-----------KSNVKANTQTNEVAQSGSETK 1093 Query: 1443 RAKINQDKEATAEERQ----VALDKINEFVNQAMTDITNNRTNQQVDDTTSQALDSIALV 1498 + + KE E++ V +K E ++ V A ++ V Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTV 1153 Query: 1499 APEHIVRAAARDAVKQQYEAKKQEIEQAEHATDEEKQVALNQLANNEKLALQNINQAVTN 1558 + A +Q AK+ + T+ N + N + Q N Sbjct: 1154 NIKEPQSQTNTTADTEQ-PAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVN 1212 Query: 1559 NDVKRVETNGIATLKGVQPHIVIKPEAQQAIKATAENQVESIKDTPHATVDELDEANQLI 1618 ++ N PH V +P + + + +A + + Q + Sbjct: 1213 SESSNKPKNRHRRSVRSVPHNV-EPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFV 1271 Query: 1619 S-DTLKQAQQEIENTNQDAAV 1638 + + K Q I + Sbjct: 1272 ALNVGKAVSQHISQLEMNNEG 1292
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 115 bits (289), Expect = 9e-33 Identities = 59/227 (25%), Positives = 102/227 (44%), Gaps = 26/227 (11%) Query: 30 IQQTAKA-----ENSVKLITNTNVAPYSGVTWMGA--------GTGFVVGNHTIITNKHV 76 ++Q A N IT+T Y+ VT++ +G VVG T++TNKHV Sbjct: 61 LEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHV 120 Query: 77 TYHM-KVGDEIKAHPNGFY--NNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFK 133 +KA P+ N G + +I Y G+ D+A+V+ + + Sbjct: 121 VDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSP---NEQNKHIG 177 Query: 134 DFTSKFNIA--SEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVSSDAIIQPGS 191 + ++ +E + N+ I+V GYP + M+ES GK+ + G + D G+ Sbjct: 178 EVVKPATMSNNAETQVNQNITVTGYP-GDKPVATMWESKGKITYLKGEAMQYDLSTTGGN 236 Query: 192 SGSPILNSKHEAIGVIYAGNKPSGESTRGFAVYFSPEIKKFIADNLD 238 SGSP+ N K+E IG+ + G AV+ + ++ F+ N++ Sbjct: 237 SGSPVFNEKNEVIGIHWGGVPNEF----NGAVFINENVRNFLKQNIE 279
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 178 bits (452), Expect = 7e-57 Identities = 64/217 (29%), Positives = 106/217 (48%), Gaps = 23/217 (10%) Query: 37 EKNVTQVKDTNNFPYNGVVSFK--------DATGFVIGKNTIITNKHV-SKDYKVGDRIT 87 + Q+ DT N Y V + A+G V+GK+T++TNKHV + + Sbjct: 73 NNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALK 132 Query: 88 AHP---NGDKGNGGIYKIKSISDYPGDEDISVMNIEEQAVERGPKGFNFNENVQAFNFAK 144 A P N D G + + I+ Y G+ D++++ + + E V+ + Sbjct: 133 AFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNK-----HIGEVVKPATMSN 187 Query: 145 DA--KVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDNILNFDAYIEPGNSGSPVLNSNN 202 +A +V+ I V GYP +ES G I +K + +D GNSGSPV N N Sbjct: 188 NAETQVNQNITVTGYPGDK-PVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKN 246 Query: 203 EVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQKHIEQ 239 EVIG+ +GG + +E+NGAV+ +++F++++IE Sbjct: 247 EVIGIHWGG---VPNEFNGAVFINENVRNFLKQNIED 280
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 182 bits (462), Expect = 4e-58 Identities = 65/230 (28%), Positives = 108/230 (46%), Gaps = 29/230 (12%) Query: 43 EVQQTAKA-----ENNVTKIQDTNIFPYTGVVAFKS--------ATGFVVGKNTILTNKH 89 ++Q A N+ +I DT Y V + A+G VVGK+T+LTNKH Sbjct: 60 PLEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKH 119 Query: 90 V-SKNYKVGDRITAHP---NSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGF 145 V + + A P N D G ++ ++I Y G+ D+++++ + Sbjct: 120 VVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNK----- 174 Query: 146 NFNDNVTPFKYAAGA--KAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTE 203 + + V P + A + + I V GYP K ++ES G + ++G ++ Y T Sbjct: 175 HIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMWESKGKITYLKGEAMQYDLSTT 233 Query: 204 SGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENID 253 GNSGSPV N NE++GIH+ V N+ N V+ ++ F+ +NI+ Sbjct: 234 GGNSGSPVFNEKNEVIGIHWGG-VPNEFNG---AVFINENVRNFLKQNIE 279
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 138 bits (349), Expect = 1e-41 Identities = 64/212 (30%), Positives = 101/212 (47%), Gaps = 18/212 (8%) Query: 36 EKNVKEITDATKAPYNSVVAFA--------GGTGVVVGKNTIVTNKHIAKSNDIFKNRVA 87 + +ITD T Y V +GVVVGK+T++TNKH+ + + + Sbjct: 73 NNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALK 132 Query: 88 AHYS---SKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFAEGA-- 142 A S G + + I +Y G+ DLAIV + + + + V + A Sbjct: 133 AFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVK-FSPNEQNKHIGEVVKPATMSNNAET 191 Query: 143 KAKDRISVIGYPKGAQTKYKMFESTGTINHISGTFIEFDAYAQPGNSGSPVLNSKHELIG 202 + I+V GYP G + M+ES G I ++ G +++D GNSGSPV N K+E+IG Sbjct: 192 QVNQNITVTGYP-GDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIG 250 Query: 203 ILYAGSGKDESEKNFGVYFTPQLKEFIQNNIE 234 I + G +E N V+ ++ F++ NIE Sbjct: 251 IHWGGVP---NEFNGAVFINENVRNFLKQNIE 279
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 396 bits (1020), Expect = e-141 Identities = 96/329 (29%), Positives = 177/329 (53%), Gaps = 24/329 (7%) Query: 1 MKMKKLVKSSVASSIALLLLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDNDKLNISQ 60 M K++ ++++ S+ L + ++ A+ + I + K T ++K ++Q Sbjct: 1 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 Query: 61 ILTFNFIKDKSYDKDTLVLKAAGNINSGYKKPNPKDYNYSQ-FYWGGKYNVSVSSESNDA 119 + F+F+KDK Y+KD L+LK G I+S N K N+ + W +YN+ + + + Sbjct: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTN-DKY 119 Query: 120 VNVVDYAPKNQNEEFQVQQTLGYSYGGDINISNGLSGGLNGSKSFSETINYKQESYRTTI 179 V++++Y PKN+ E V QTLGY+ GG+ + L G NGS ++S++I+Y Q++Y + + Sbjct: 120 VSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGG--NGSFNYSKSISYTQQNYVSEV 177 Query: 180 DRKTNHKSIGWGVEAHKIMNNGWGPYGRDSYDPTYGNELFLGGRQSSSNAGQNFLPTHQM 239 +++ N KS+ WGV+A+ + ++LF+G + S + F+P ++ Sbjct: 178 EQQ-NSKSVLWGVKANSFAT-------ESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSEL 229 Query: 240 PLLARGNFNPEFISVLSHKQNDTKKSKIKVTYQREMD---------RYTNQWNRLHWIGN 290 P L + FNP FI+ +SH++ + S+ ++TY R MD Y N + H + N Sbjct: 230 PPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHN 289 Query: 291 NYKNQNTVTFTSTYEVDWQNHTVKLIGTD 319 + N+N +T YEV+W+ H +K+ G + Sbjct: 290 AFVNRN---YTVKYEVNWKTHEIKVKGQN 315
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 431 bits (1110), Expect = e-155 Identities = 213/318 (66%), Positives = 255/318 (80%), Gaps = 10/318 (3%) Query: 1 MFKKKMLAATLSVGLIAPLASPIQE-SRANTNIENIGDGA--EVIKRTEDVSSKKWGVTQ 57 M K K+L TLSV L+APLA+P+ E ++A + E+IG G+ E+IKRTED +S KWGVTQ Sbjct: 1 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 Query: 58 NVQFDFVKDKKYNKDALIVKMQGFINSRTSFSDVKGSGYELTKRMIWPFQYNIGLTTKDP 117 N+QFDFVKDKKYNKDALI+KMQGFI+SRT++ + K + + K M WPFQYNIGL T D Sbjct: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNH--VKAMRWPFQYNIGLKTNDK 118 Query: 118 NVSLINYLPKNKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFNYSKTISYTQKSYVSEVD 177 VSLINYLPKNKIE+T+V QTLGYNIGGNFQSAPS+GGNGSFNYSK+ISYTQ++YVSEV+ Sbjct: 119 YVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVE 178 Query: 178 KQNSKSVKWGAKANEFVTPDGKKSAHDRYLFVQSPNGPTGSAREYFAPDNQLPPLVQSGF 237 +QNSKSV WG KAN F T G+KSA D LFV + R+YF PD++LPPLVQSGF Sbjct: 179 QQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPH-SKDPRDYFVPDSELPPLVQSGF 237 Query: 238 NPSFITTLSHEKGSSDTSEFEISYGRNLDITYA----TLFPRTGIYAERKHNAFVNRNFV 293 NPSFI T+SHEKGSSDTSEFEI+YGRN+D+T+A T + + + R HNAFVNRN+ Sbjct: 238 NPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYT 297 Query: 294 VRYEVNWKTHEIKVKGHN 311 V+YEVNWKTHEIKVKG N Sbjct: 298 VKYEVNWKTHEIKVKGQN 315
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 195 bits (497), Expect = 4e-64 Identities = 109/261 (41%), Positives = 155/261 (59%), Gaps = 11/261 (4%) Query: 4 LSTVIIILILEIVFHNMN-YVNAQPDPKLDELNKVSDYKNNKGTMGNVMNLYTSPPVEGR 62 +S VI+I L +V N +QPDP D+L+K S++ GTMGN+ LY V Sbjct: 7 ISRVILIFALILVISTPNVLAESQPDPMPDDLHKSSEFT---GTMGNMKYLYDDHYVSAT 63 Query: 63 GVINSRQFLSHDLIFPI---EYKSYNEVKTELENTELANNYKDKKVDIFGVPYFYTCIIP 119 V + +FL+HDLI+ I + K+Y++VKTEL N +LA YKD+ VD++G Y+ C Sbjct: 64 KVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKDEVVDVYGSNYYVNCYFS 123 Query: 120 KSEPDINQNFGGCCMYGGLTF---NSSENERDKLITVQVTIDNRQSLGFTITTNKNMVTI 176 + G CMYGG+T N +N + + V+V + R ++ F + T+K VT Sbjct: 124 SKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTA 183 Query: 177 QELDYKARHWLTKEKKLYEFDGSAFESGYIKFTEKNNTSFWFDLFPKKELVPFVPYKFLN 236 QELD KAR++L +K LYEF+ S +E+GYIKF E N +FW+D+ P F K+L Sbjct: 184 QELDIKARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDK-FDQSKYLM 242 Query: 237 IYGDNKVVDSKSIKMEVFLNT 257 +Y DNK VDSKS+K+EV L T Sbjct: 243 MYNDNKTVDSKSVKIEVHLTT 263
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 155 bits (394), Expect = 9e-49 Identities = 76/265 (28%), Positives = 124/265 (46%), Gaps = 21/265 (7%) Query: 2 RLFYIAAIII-TLLCLINNNYVNAEV----DKKDLKKKSDLDSSKLFNLTSYYTDITWQL 56 RLF I+I L+ +I+ V AE DL K S+ + + N+ Y D + Sbjct: 4 RLFISRVILIFALILVISTPNVLAESQPDPMPDDLHKSSEF-TGTMGNMKYLYDDH--YV 60 Query: 57 DESNKISTDQLLNNTIILKNIDISVLKTSSLKVEFNSSDLANQFKGKNIDIYGLYFGNKC 116 + S D+ L + +I D + +K E + DLA ++K + +D+YG + C Sbjct: 61 SATKVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKDEVVDVYGSNYYVNC 120 Query: 117 -------VGLTEEKTSCLYGGVTIHDGNQLDEEKV--IGVNVFKDGVQQEGFVIKTKKAK 167 VG +C+YGG+T H+GN D + + V V+++ F ++T K Sbjct: 121 YFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKS 180 Query: 168 VTVQELDTKVRFKLENLYKIYNKDTGNIQKGCIFFHSHNHQDQSFYYDLYNVKGSVG--A 225 VT QELD K R L N +Y ++ + G I F +N +F+YD+ G + Sbjct: 181 VTAQELDIKARNFLINKKNLYEFNSSPYETGYIKFIENN--GNTFWYDMMPAPGDKFDQS 238 Query: 226 EFFQFYSDNRTVSSSNYHIDVFLYK 250 ++ Y+DN+TV S + I+V L Sbjct: 239 KYLMMYNDNKTVDSKSVKIEVHLTT 263
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 39.7 bits (92), Expect = 8e-05 Identities = 41/217 (18%), Positives = 79/217 (36%), Gaps = 20/217 (9%) Query: 588 AIEAARESTKEQLRDYVKTSDYKTDKDGIVERLDTA-EAERTTLKGEIKDKVTLNEYRNG 646 A+E A++ + VK + + A +AE TL G+ NE Sbjct: 190 AVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGK------RNELAQA 243 Query: 647 LEEQKQYTD--DQLSDLSNNPEIKASIEQANQEAQEALKSYIDAQDNLKEKESQAYADGK 704 + K+ + +LS +N+P +A + A K + Q + E++ Sbjct: 244 SAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINA 303 Query: 705 ISEEEQRAIQDAQAKLEEAKQNAELKARNAEKKANAYTDNKVKESTDAQR---RTLT-RY 760 + Q+AI N +K N ++++K++ DA +TLT +Y Sbjct: 304 DITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDATVSFYQTLTEKY 363 Query: 761 GSQIIQNGKEI-------KLRTTKEEFNATNRTLSNI 790 G + + +E+ K+ E A + + Sbjct: 364 GEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDVL 400
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 36.2 bits (83), Expect = 0.001 Identities = 86/433 (19%), Positives = 168/433 (38%), Gaps = 54/433 (12%) Query: 16 AANLNRSFA---------EIKRNFKTLNSDLKLTGNNFKYTEKSTHSYKQRIKELDGTIT 66 N N++ A E+K+ K L L+ + K EK S +++ Sbjct: 588 TLNFNKAVADAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNKMEAKAQ 647 Query: 67 GYKKNVDDLAKQYGKVSQEQGENSAEAQKLRQEYNKQANELNFLEKELEKTTTEFEEFKK 126 + D++ K + A AQ L+ + +++L + K L+ F+EFK Sbjct: 648 ANSQK-DEIFALINKEANRDARAIAYAQNLKGIKRELSDKLENVNKNLKDFDKSFDEFKN 706 Query: 127 AQVEAQRMAESGWGKTSKVFESMGPKLTKMGDGLKSIGKGLMIGVTAPVLGIAAASGKAF 186 + + K + +++ + +G + I K V + AA + Sbjct: 707 GK-------NKDFSKAEETLKALKGSVKDLGINPEWISK---------VENLNAALNEFK 750 Query: 187 AEVDKGLDTVTQATGATGGELKKLQNSFKDVYGN--FPEDAETVGGVLGEVNTRLGFTGK 244 +K VTQA L+NS KDV N + + + + F+ Sbjct: 751 NGKNKDFSKVTQAK-------SDLENSVKDVIINQKVTDKVDNLNQAVSVAKATGDFSR- 802 Query: 245 ELESATESFLKFSHITGSDGVQAVQLITRAMGDAGIEADEYQSVLDMVAKAAQASGISVD 304 +E A FS + Q + + +A +++ YQSV + V +G+S Sbjct: 803 -VEQALADLKNFSKEQLAQQAQKNESL-----NARKKSEIYQSVKNGVNGTLVGNGLS-Q 855 Query: 305 TLADSITKYGAPMRAMGFEMKESIALFSQWEKSGVNTEIAFSGLKKAISNWGKAGKDP-- 362 A +++K + ++ E+ + F+ +G+ E ++ + K + + ++P Sbjct: 856 AEATTLSKNFSDIKK---ELNAKLGNFNNNNNNGLKNEPIYAKVNKKKAGQAASLEEPIY 912 Query: 363 REEFKKTLAEIERTPDIASATSLAIEA--FGAKAGPDLADAIKGGRFSYQEFLKTIEDSQ 420 + KK A+I+R IAS + +A F K + D K G QE + I++ Sbjct: 913 AQVAKKVNAKIDRLNQIASGLGVVGQAAGFPLKRHDKVDDLSKVGLSRNQELAQKIDN-- 970 Query: 421 GTVNQTFKDSESG 433 +NQ ++++G Sbjct: 971 --LNQAVSEAKAG 981
>PF06580#Sensor histidine kinase Length = 349 Score = 26.8 bits (59), Expect = 0.028 Identities = 9/36 (25%), Positives = 18/36 (50%), Gaps = 5/36 (13%) Query: 67 ERLEQARLERKLERKRKREAELR----RKKPH-LFN 97 + +QA +++ +EA+L + PH +FN Sbjct: 142 KNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFN 177
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 24.4 bits (53), Expect = 0.039 Identities = 7/19 (36%), Positives = 11/19 (57%) Query: 35 EEIETFFLDPTKTYVFVGS 53 ++ET FL + Y F+ S Sbjct: 109 SDLETVFLTTSTEYSFLSS 127
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 44.7 bits (105), Expect = 6e-06 Identities = 57/316 (18%), Positives = 103/316 (32%), Gaps = 20/316 (6%) Query: 2122 PQANNNSSADASTNSPTMDNDVTSKPEVESTNNG---TTDKPVTETDNATPAESTTNN-- 2176 P+ + +TN T +N P V S N + PV ATP+E+T Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 2177 ----NSTTTATNENAPTGSTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQS 2232 S T NE T +TA A ++ + V S + + E++ Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 2233 TNGKVAQPKS--ENKAKAEKDGRDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEEST 2290 T + K+ E + E S E + P A+ N P+ K+ + T Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQT 1162 Query: 2291 TNQTDAGQLKSETNVASNEADKSPSKADT----EVSNKPSTSASSEAKDKMTSTNVSQKD 2346 D Q ET+ + + +T + + +T A+++ S+N + Sbjct: 1163 NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNR 1222 Query: 2347 DTATADTNDTQKSVGPVANNKAKDMQTNDTQKSVGSAANNKATQNDGANASPATVSNG-S 2405 + + ++N + S N + A A ++ G + Sbjct: 1223 HRRSVRSVPHNVEPATTSSNDRS----TVALCDLTSTNTNAVLSDARAKAQFVALNVGKA 1278 Query: 2406 HSMHQDMLNVTKPEEN 2421 S H L + + Sbjct: 1279 VSQHISQLEMNNEGQY 1294 Score = 42.0 bits (98), Expect = 4e-05 Identities = 47/318 (14%), Positives = 104/318 (32%), Gaps = 9/318 (2%) Query: 1073 NNGSTTEEKEAAKQQVQTEKTAADAAIDAAHSNVEVEAAKNAEIAKI-EAIQPATTTKDN 1131 NG +++ QT T + ++V + N EIA++ EA P Sbjct: 974 VNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATP 1033 Query: 1132 AKQAIATKANERKTAIAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTT 1191 ++ N ++ ++T + ++ A +A SN++A N+V Q+ + Sbjct: 1034 SETTETVAENSKQE--SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSE 1091 Query: 1192 GETSIDQVTPTVNKKATARNEITAILNNKLQEIQATPDATDEEKQAADAEANTENGKANQ 1251 + T T K TA E + ++ Q P T + + + Sbjct: 1092 TKE-----TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPA 1146 Query: 1252 AISAATTNAQVDEAKANAEAAINAVTPKVVKKQAAKDEIDQLQATQTNVINNDQNATNEE 1311 + T N + +++ N A + T +V+ N +N T Sbjct: 1147 RENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPAT 1206 Query: 1312 KEAAIQQLATAVTDAKNNITAATDDNGVDTAKDAGKNSIQSTQPATAVKSNAKNEVDQAV 1371 + + ++ ++ + + + V+ A + + + +N + A Sbjct: 1207 TQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDR-STVALCDLTSTNTNAVLSDAR 1265 Query: 1372 TTQNQAIDNTTGATTEEK 1389 N A ++ Sbjct: 1266 AKAQFVALNVGKAVSQHI 1283 Score = 33.9 bits (77), Expect = 0.010 Identities = 61/312 (19%), Positives = 105/312 (33%), Gaps = 18/312 (5%) Query: 1021 DIDNATANTDVDNAKTTNEATIAAITPDANVKPAAKQAIADKVQAQETAIDANNGSTTEE 1080 D+ N TTN T I D P+ + IA +A S T E Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038 Query: 1081 K--EAAKQQVQTEKTAADAAIDAAHSNVEVEAAKNAEIAKIEAIQPATTTKDNAKQAIAT 1138 E +KQ+ +T + A + N EV + + A T + Q+ + Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNV-------KANTQTNEVAQSGSE 1091 Query: 1139 KANERKTAIAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTTGETSIDQ 1198 + T +T + EE A + V + S + Q++ Q + D Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREND- 1150 Query: 1199 VTPTVN-KKATARNEITAILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAAT 1257 PTVN K+ ++ TA +E + + E + + N + AT Sbjct: 1151 --PTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENT--TPAT 1206 Query: 1258 TNAQVDEAKANAEAAINAVTPKVVKKQ---AAKDEIDQLQATQTNVINNDQNATNEEKEA 1314 T V+ +N + + + V A D+ ++ + + NA + A Sbjct: 1207 TQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARA 1266 Query: 1315 AIQQLATAVTDA 1326 Q +A V A Sbjct: 1267 KAQFVALNVGKA 1278 Score = 33.9 bits (77), Expect = 0.012 Identities = 45/305 (14%), Positives = 93/305 (30%), Gaps = 14/305 (4%) Query: 804 KNEEIFKIENITDSTQTKMDAYKEVRQAATARKAQNATVSNATDEEVAEANAAVDAAQTE 863 E K E+ T + + A++A++ +N EVA++ + QT Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 864 GLHDIQVVKSQQEVADTKAKVLDKINAIQTQAKVKPAADTEVENAYNTRKQEIQNSNAST 923 + V+ +++ A + + ++ + +Q K V+ ++ N Sbjct: 1099 ETKETATVEKEEK-AKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 924 TEEKEAAYTELDAKKQEARTNLDAANTNSDVTTAKDNGIAAINQVQAATTKKSDAKAEIA 983 + + + + +E +N++ T T N + + T + +E + Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVT-ESTTVNTGNSVVENPENTTPATTQPTVNSESS 1216 Query: 984 QKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANADIDNATANTDVDNAKTTNEATIA 1043 K R + E V + N A AK A Sbjct: 1217 NKPKNR-HRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVA--- 1272 Query: 1044 AITPDANVKPAAKQAIADKV---QAQETAIDANNGSTTEEKEAAKQQVQTEKTAADAAID 1100 NV A Q I+ + Q +N + ++ ++ T D Sbjct: 1273 -----LNVGKAVSQHISQLEMNNEGQYNVWVSNTSMNKNYSSSQYRRFSSKSTQTQLGWD 1327 Query: 1101 AAHSN 1105 SN Sbjct: 1328 QTISN 1332 Score = 32.3 bits (73), Expect = 0.034 Identities = 32/210 (15%), Positives = 63/210 (30%), Gaps = 4/210 (1%) Query: 34 TTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPAAQPANQGGQANPAGGAAQPAGQG 93 T + +Q P Q QP A + +P Q N QPA + Sbjct: 1116 TEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKET 1175 Query: 94 NQADPNNAAQAQPGNQ--AAPANQAGQGNNQATPNNNATPANQTQPANAPA-AAQPAAPV 150 + ++ N + N P N+ +N+ + + + + P Sbjct: 1176 SSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE 1235 Query: 151 AANAQTQDPNASNTGE-GSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIG 209 A + D + + S NT D + V+ ++ + N G+ Sbjct: 1236 PATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYN 1295 Query: 210 FVNSELRRSDMFDKNNPQNYQAKGNVAALG 239 S + + + + + +K LG Sbjct: 1296 VWVSNTSMNKNYSSSQYRRFSSKSTQTQLG 1325
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 144 bits (364), Expect = 3e-40 Identities = 98/416 (23%), Positives = 194/416 (46%), Gaps = 14/416 (3%) Query: 8 TTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIP 67 + R N I+ + I +F ++LN+ +LN +LP I + N +++ W+ T FML + Sbjct: 8 SNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTA 67 Query: 68 LTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPN-FGVLMLARVIQAMGAGVLMPLMQFT 126 + L D++ + L L + GS++ + + F +L++AR IQ GA L+ Sbjct: 68 VYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 127 LFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFVFGL 186 + KE+RG A GL G ++ +GP + G+I W +++++ + + V L Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPFL 185 Query: 187 VSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALIISMVIIYLF 246 + + D + ++ ++G + FT+ I LI+S++ +F Sbjct: 186 MKLLKKEVRIKGHFDIKGIILMSVGIVFFML---------FTTSYSISFLIVSVLSFLIF 236 Query: 247 IRRQFNITNVLLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGL 306 ++ +T+ ++ + KN F + + II ++ G ++P +++ LS G Sbjct: 237 VKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGS 296 Query: 307 VIM-PGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVY 365 VI+ PG + I G D+ GP ++ G T L+++ + FL TS+ I++ Sbjct: 297 VIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIV 356 Query: 366 AIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFG 421 + S I+T +SL+ +E G +++NF ++ G A++ L+S Sbjct: 357 FVLGGL-SFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 457 bits (1178), Expect = e-162 Identities = 163/441 (36%), Positives = 271/441 (61%), Gaps = 20/441 (4%) Query: 1 MIQTLVNFFRTKEVRNKIFFTLAMLVIFKIGTYIPAPGVNPAA----FDNPQGSQGATEL 56 M+ FRT ++R K+ FTLA++V++++GT+IP PGV+ G+QG L Sbjct: 1 MLTAFARAFRTPDLRKKLLFTLAIIVVYRVGTHIPIPGVDYKNVQQCVREASGNQGLFGL 60 Query: 57 LNTFGGGALKRFSIFAMGIVPYITASIVMQLLQMDIVPKFSEWAKQGEVGRRKLNNVTRY 116 +N F GGAL + +IFA+GI+PYITASI++QLL + ++P+ K+G+ G K+ TRY Sbjct: 61 VNMFSGGALLQITIFALGIMPYITASIILQLLTV-VIPRLEALKKEGQAGTAKITQYTRY 119 Query: 117 LAISLAFIQSIGMAFQFNN-------YLKGALIINQSIMSYLLIALVLTAGTAFLIWLGD 169 L ++LA +Q G+ + + G ++ +QSI + + + + +TAGT ++WLG+ Sbjct: 120 LTVALAILQGTGLVATARSAPLFGRCSVGGQIVPDQSIFTTITMVICMTAGTCVVMWLGE 179 Query: 170 QITQFGVGNGISIIIFAGILSTLPASLIQFGQTAFVGQEDTSLAWLKVLGLLVSLILLTV 229 IT G+GNG+SI++F I +T P++L + + W++ ++ +++ Sbjct: 180 LITDRGIGNGMSILMFISIAATFPSALWAIKKQGTLAG-----GWIEFGTVIAVGLIMVA 234 Query: 230 GAIYVLEAVRKIPIQYAKKQTAQRL-GSQATYLPLKVNSAGVIPVIFAMAFFLLPRTLTL 288 ++V +A R+IP+QYAK+ +R G +TY+PLKVN AGVIPVIFA + +P + Sbjct: 235 LVVFVEQAQRRIPVQYAKRMIGRRSYGGTSTYIPLKVNQAGVIPVIFASSLLYIPALVAQ 294 Query: 289 FYPDKEWAQNIA--NAANPSSNVGMVVYIVLIILFTYFYAFVQVNPEKMADNLKKQGSYV 346 F ++ N + +V Y +LI+ F +FY + NPE++ADN+KK G ++ Sbjct: 295 FAGGNSGWKSWVEQNLTKGDHPIYIVTYFLLIVFFAFFYVAISFNPEEVADNMKKYGGFI 354 Query: 347 PGIRPGEQTKKYITKVLYRLTFVGSIFLAVISILPILATKFMGLPQSIQIGGTSLLIVIG 406 PGIR G T +Y++ VL R+T+ GS++L +I+++P +A G Q+ GGTS+LI++G Sbjct: 355 PGIRAGRPTAEYLSYVLNRITWPGSLYLGLIALVPTMALVGFGASQNFPFGGTSILIIVG 414 Query: 407 VAIETMKSLEAQVSQKEYKGF 427 V +ET+K +E+Q+ Q+ Y+GF Sbjct: 415 VGLETVKQIESQLQQRNYEGF 435
>PF06872#EspG protein Length = 398 Score = 26.2 bits (57), Expect = 0.028 Identities = 13/31 (41%), Positives = 18/31 (58%) Query: 73 PKTNEPTRVGYKFVDGKKVRIAKKSGEEIKS 103 P NE RV KF DG +RI+ + E I++ Sbjct: 87 PAHNELGRVYAKFSDGSSLRISVTNSELIEA 117
>SECA#SecA protein signature. Length = 901 Score = 656 bits (1695), Expect = 0.0 Identities = 287/835 (34%), Positives = 450/835 (53%), Gaps = 68/835 (8%) Query: 10 NELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGVDTLDTLLPEAYAVAR 69 N+ L+ +RK+V IN E++ SD+ LK KT EF+ RL G + L+ L+PEA+AV R Sbjct: 14 NDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKG-EVLENLIPEAFAVVR 72 Query: 70 EASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTN 129 EAS RV GM +VQL+G +VL+E IAEM+TGEGKTLTAT+P YLNAL+GKG +++T N Sbjct: 73 EASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVN 132 Query: 130 DYLAKRDFEEMQPLYEWLGLTASLGFVDIVDYEYQKGEKRNIYEHDIIYTTNGRLGFDYL 189 DYLA+RD E +PL+E+LGLT V I KR Y DI Y TN GFDYL Sbjct: 133 DYLAQRDAENNRPLFEFLGLT-----VGINLPGMPAPAKREAYAADITYGTNNEYGFDYL 187 Query: 190 IDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLI 249 DN+A S E + +L+Y ++DEVDSI++D A+TPL+ISG S ++ V + + LI Sbjct: 188 RDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLI 247 Query: 250 E-----------DVHFKMKKTKKEIWLLNQGIEAAQSYFNV-------EDLYSEQAMVLV 291 + HF + + +++ L +G+ + E LYS ++L+ Sbjct: 248 RQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLM 307 Query: 292 RNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQAGLHQAIEAKEGMEVST 351 ++ ALRA LF +VDY V +G+++++D TGR + G + GLHQA+EAKEG+++ Sbjct: 308 HHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQN 367 Query: 352 DKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEPDKV 411 + +A+ITFQN F+L+E +GMT T EF +Y V PT++ + R D PD V Sbjct: 368 ENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLV 427 Query: 412 FRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKE 471 + + EK A+I DI E G+PVL+ T + E +E S L + I +N+L A+ A E Sbjct: 428 YMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANE 487 Query: 472 AQMIAEAGQIGSMTVATSMAGRGTDIKLG-----------------------------EG 502 A ++A+AG ++T+AT+MAGRGTDI LG + Sbjct: 488 AAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDA 547 Query: 503 VEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENN 562 V GGL +I E E+ R+D QLRGRSGRQGD GSS Y+S++D L++ ++ ++ Sbjct: 548 VLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMM 607 Query: 563 QLYSLDAQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEER 622 + + + + + AQR E + R+ E++ + QR +Y +R Sbjct: 608 RKLGMKPGEAIEHPWVTKAIA----NAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQR 663 Query: 623 NRVLEIDDAENRDFKALAKDVFEMFVNEE---KVLTKSRVVEYIYQNLSFQFNKDVACVN 679 N +L++ D ++ +DVF+ ++ + L + + + + L F+ D+ Sbjct: 664 NELLDVSDVSET-INSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 680 FKDKQAVVT------FLLEQFEKQLALNRKNMQSAYYYNIFVQKVFLKAIDSCWLEQVDY 733 + DK+ + +L Q + ++ + A F + V L+ +DS W E + Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQ-RKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAA 781 Query: 734 LQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKE 788 + L+ ++ R Q++ EY R + F M ++K ++ + + + +E Sbjct: 782 MDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEE 836
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 130 bits (329), Expect = 4e-36 Identities = 93/440 (21%), Positives = 181/440 (41%), Gaps = 52/440 (11%) Query: 4 LLQQYEYKIIYKRMLYTCFILFIYILGTNISI--VSYNDMQ------VKHESFFKIAISN 55 + + + K++L+T I+ +Y +GT+I I V Y ++Q ++ F + Sbjct: 5 FARAFRTPDLRKKLLFTLAIIVVYRVGTHIPIPGVDYKNVQQCVREASGNQGLFGLVNMF 64 Query: 56 MGGDVNTLNIFTLGLVPWLTSMIILMLISYRNMDKYMKQTSLEKHYKE------------ 103 GG + + IF LG++P++T+ IIL L++ + LE KE Sbjct: 65 SGGALLQITIFALGIMPYITASIILQLLT-------VVIPRLEALKKEGQAGTAKITQYT 117 Query: 104 RILTLILSVIQSYFVIHEYVSKERVHQDN-------------IYLTILILVTGTMLLVWL 150 R LT+ L+++Q ++ S + + ++ + GT +++WL Sbjct: 118 RYLTVALAILQGTGLVATARSAPLFGRCSVGGQIVPDQSIFTTITMVICMTAGTCVVMWL 177 Query: 151 ADKNSRYGIAGPMPIVMVSIIKSMMHQKMEYI------DASHIVIALLIILVIITLFILL 204 + + GI M I+M I + + I I +I + +I + +++ Sbjct: 178 GELITDRGIGNGMSILMFISIAATFPSALWAIKKQGTLAGGWIEFGTVIAVGLIMVALVV 237 Query: 205 FIELVEVRIPYI----DLMNVSATNMKSYLSWKVNPAGSITLMMSISAFVFLKSGIHFIL 260 F+E + RIP + S +Y+ KVN AG I ++ + S F Sbjct: 238 FVEQAQRRIPVQYAKRMIGRRSYGGTSTYIPLKVNQAGVIPVIFASSLLYIPALVAQFAG 297 Query: 261 SMFNKSISDDMPMLTFDSPVGISVYLVIQMLLGYFLSRFLINTKQKSKDFLKSGNYFSGV 320 + + D P+ I Y ++ + +F N ++ + + K G + G+ Sbjct: 298 GNSGWKSWVEQNLTKGDHPIYIVTYFLLIVFFAFFYVAISFNPEEVADNMKKYGGFIPGI 357 Query: 321 KPGKDTERYLNYQARRVCWFGSALVTVIIGIPLYFTLFVPHLSTEIYFS-VQLIVLVYIS 379 + G+ T YL+Y R+ W GS + +I +P L S F ++++V + Sbjct: 358 RAGRPTAEYLSYVLNRITWPGSLYLGLIALVP-TMALVGFGASQNFPFGGTSILIIVGVG 416 Query: 380 INIAETIRTYLYFDKYKPFL 399 + + I + L Y+ FL Sbjct: 417 LETVKQIESQLQQRNYEGFL 436
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 55.1 bits (132), Expect = 3e-09 Identities = 237/1070 (22%), Positives = 425/1070 (39%), Gaps = 12/1070 (1%) Query: 1098 SDSMSISTSFSDSTSDSKSASTASSESISQSASTSTSGSVSTSTSLSTSNSERTSTSVSD 1157 + + ++ + S S + + T +T S ST ++ + Sbjct: 106 LHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQTIEIATYG 165 Query: 1158 STSLSTSESDSISESTSTSDSISEAISASESTSISLSESNSTSDSESQSASAFLSESLSE 1217 ST T +S I+ ST + + + S + ++ST + S ES Sbjct: 166 STLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQM 225 Query: 1218 STSESTSESVSSSTSESTSLSDSTSESGSTSTSLSNSTSGSASISTSTSISESTSTFKSE 1277 + ST + S + S T+ S+ + ST + S+ T+ ST T + Sbjct: 226 AGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKG 285 Query: 1278 SVSTSLSMSTSTSLSNSTSLSTSLSDSTSDSKSDSLSTSMSTSDSISTSKSDSISTSTSL 1337 S T+ ST T+ ++S+ ++ S T+ +S + ST + S + ST Sbjct: 286 SDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGT 345 Query: 1338 SGSTSESESDSTSSSESKSDSTSMSISMSQSTSGSTSTSTSTSLSDSTSTSLSLSASMNQ 1397 +G S + S+ + DS+ + S T+ S T+ S T+ + S + Sbjct: 346 AGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYG 405 Query: 1398 SGVDSNSASQSASNSTSTSTSESDSQSTSTYTSQSTSQSESTSTSTSLSDSTSISKSTSQ 1457 S + S + ST T++ S T+ Y S T+ +S+ + S T+ S+ Sbjct: 406 STQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLT 465 Query: 1458 SGSTSTSASLSGSESESDSQSISTSASESTSESASTSLSDSTSTSNSGSASTSTSLSNSA 1517 +G ST + GS+ + S ST+ ES+ + S + S + ST + + Sbjct: 466 AGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNE 525 Query: 1518 SASESDSSSTSLSDSTSASMQSSESDSQSTSASLSDSLSTSTSNRMSTIASLSTSVSTSE 1577 S + STS + + S+ + S ++ S+ + ST + ST Sbjct: 526 SDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGT 585 Query: 1578 SGSTSESTSESDSTSTSLSDSQSTSRSTSASGSASTSTSTSDSRSTSASTSTSMRTSTSD 1637 +GS S + ST T+ S T+ S + S T+ STS + + S + Sbjct: 586 AGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYG 645 Query: 1638 SQSMSLSTSTSTSMSDSTSLSDSVSDSTSDSTSASTSGSMSVSISLSDSTSTSTSASEVM 1697 S + S T+ ST + SD T+ S ST+G+ S I+ ST T+ S + Sbjct: 646 STQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSILT 705 Query: 1698 SASISDSQSMSESVNDSESVSESNSESDSKSMSGSTSVSDSGSLSVSTSLRKSESVSESS 1757 + S + S S S S + +DS ++G S + S T+ S + Sbjct: 706 AGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQTAREQ 765 Query: 1758 SLSGSQSMSDSVSTSDSSSLSVSTSLRSSESVSESDSLSDSKSTSGSTSTSTSGSLSTST 1817 S+ + S S + +DSS ++ S +++ S + S T+ S T+G STST Sbjct: 766 SVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGYGSTST 825 Query: 1818 SLSGSESVSESTSLSDSISMSDSTSTSDSDSLSGSISLSGSTSLSTSDSLSDSKSLSSSQ 1877 + + S ++ S + S T+ S + S + STS + DS ++ Sbjct: 826 AGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSLIAGYG 885 Query: 1878 SMSGSESTSTSVSDSQSSSTSNSQFDSMSISASESDSMSTSDSSNISGSNSTSTSLSTSD 1937 S + S + S+ T+ D + S S + S GS T++ ST Sbjct: 886 STQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTLM 945 Query: 1938 SMSGSVSVSTSTSLSDSISGSTSVSDSSSTSTSTSLSDSMSQSQSTSTSASGSLSTSIST 1997 + GS + S + GSTS++ S+ + S + QST T+ GS T+ + Sbjct: 946 AGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEHS 1005 Query: 1998 SMSMSASTSSSQSTSVSTSLSTSDSISDST----------SISISGSQSTVESESTSDST 2047 S + S++ + + S+ ++ S S S ISG +S + + S Sbjct: 1006 STLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVLTAGYGSSLI 1065 Query: 2048 SISDSESLSTSDSDSTSTSTSDSTSGSTSTSIS--ESLSTSGSGSTSVSDSTSMSESDST 2105 S S + S+ ++ S +G ST I+ S+ +G GS+ + S S + Sbjct: 1066 SGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGYRSTLISGAD 1125 Query: 2106 SVSMSQDKSDSTSISDSESVSTSTSTSLSTSDSTSTSESLSTSMSGSQSI 2155 SV M+ ++ + +DS + S L+ ++S T+ S +G+ I Sbjct: 1126 SVQMAGERGKLIAGADSTQTAGDRSKLLAGNNSYLTAGDRSKLTAGNDCI 1175 Score = 53.2 bits (127), Expect = 1e-08 Identities = 176/773 (22%), Positives = 305/773 (39%), Gaps = 2/773 (0%) Query: 1408 SASNSTSTSTSESDSQSTSTYTSQSTSQSESTSTSTSLSDSTSISKSTSQSGSTSTSASL 1467 + + +E + S + + T D+T S ST + + + Sbjct: 106 LHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQTIEIATYG 165 Query: 1468 SGSESESDSQSISTSASESTSESASTSLSDSTSTSNSGSASTSTSLSNSASASESDSSST 1527 S SQ I+ S T+ +ST ++ ST +G+ ST + S + +SS Sbjct: 166 STLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQM 225 Query: 1528 SLSDSTSASMQSSESDSQSTSASLSDSLSTSTSNRMSTIASLSTSVSTSESGSTSESTSE 1587 + ST M+ S+ + S + S+ + ST + S T+ GST + Sbjct: 226 AGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKG 285 Query: 1588 SDSTSTSLSDSQSTSRSTSASGSASTSTSTSDSRSTSASTSTSMRTSTSDSQSMSLSTST 1647 SD T+ S + + S+ +G ST T+ +S T+ ST SD + ST T Sbjct: 286 SDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGT 345 Query: 1648 STSMSDSTSLSDSVSDSTSDSTSASTSGSMSVSISLSDSTSTSTSASEVMSASISDSQSM 1707 + S + S + DS+ + GS + SD T+ S + S + Sbjct: 346 AGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYG 405 Query: 1708 SESVNDSESVSESNSESDSKSMSGSTSVSDSGSLSVSTSLRKSESVSESSSLSGSQSMSD 1767 S ES + S + GS + GS + + S+ +G S Sbjct: 406 STQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLT 465 Query: 1768 SVSTSDSSSLSVSTSLRSSESVSESDSLSDSKSTSGSTSTSTSGSLSTSTSLSGSESVSE 1827 + S ++ S S S + S + GST T+ GS T+ S + +E Sbjct: 466 AGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNE 525 Query: 1828 STSLSDSISMSDSTSTSDSDSLSGSISLSGSTSLSTSDSLSDSKSLSSSQSMSGSESTST 1887 S ++ S S + + S + GS + S+ T+ S + S +G ST T Sbjct: 526 SDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGT 585 Query: 1888 SVSDSQSSSTSNSQFDSMSISASESDSMSTSDSSNISGSNSTSTSLSTSDSMSGSVSVST 1947 + SDS + S + S+ + ST + S + S ST+ + S ++ Sbjct: 586 AGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYG 645 Query: 1948 STSLSDSISGSTSVSDSSSTSTSTSLSDSMSQSQSTSTSASGSLSTSISTSMSMSASTSS 2007 ST + S T+ S+ T+ S + S ST+ + S ++ ST + S + Sbjct: 646 STQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSILT 705 Query: 2008 SQSTSVSTSLSTSDSISDSTSISISGSQSTVESESTSDSTSISDSESLSTSDSDSTSTST 2067 + S T+ SD S S S +G+ S++ + S T+ S + S T+ Sbjct: 706 AGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQTAREQ 765 Query: 2068 SDSTS--GSTSTSISESLSTSGSGSTSVSDSTSMSESDSTSVSMSQDKSDSTSISDSESV 2125 S T+ GSTST+ ++S +G GST + S+ + S +Q++SD T+ S S Sbjct: 766 SVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGYGSTST 825 Query: 2126 STSTSTSLSTSDSTSTSESLSTSMSGSQSISDSTSTSMSGSTSTSESNSMHPS 2178 + + S+ ++ ST T+ S +G S + S + S S + + S Sbjct: 826 AGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDS 878 Score = 53.2 bits (127), Expect = 1e-08 Identities = 233/1050 (22%), Positives = 411/1050 (39%), Gaps = 2/1050 (0%) Query: 759 TSGSTQQSQSVSTSKADSQSASTSTSGSIVVSTSASTSKSTSVSLSDSVSASKSLSTSES 818 TS + A ++ + S + D+ S S +++ Sbjct: 99 TSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQT 158 Query: 819 NSVSSSTSTSLVNSQSVSSSMSGSVSKSTSLSDSISNSNSTEKSESLSTSTSDSLRTSTS 878 +++ ST QS + GS + S I+ ST + + ST + T T+ Sbjct: 159 IEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTA 218 Query: 879 LSDSLSMSTSGSLSKSQSLSTSISGSSSTSASLSDSTSNAISTSTSLSESASTSDSISIS 938 +S M+ GS S +G ST + DS+ A ST + S+ + S Sbjct: 219 GEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGS 278 Query: 939 NSIANSQSASTSKSDSQSTSISLSTSDSKSMSTSESLSDSTSTSGSVSGSLSIAASQSVS 998 A S T+ S T+ + S+ + ST + +ST T+G GS A S Sbjct: 279 TQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGY--GSTQTAQKGSDL 336 Query: 999 TSTSDSMSTSEIVSDSISTSGSLSASDSKSMSVSSSMSTSQSGSTSESLSDSQSTSDSDS 1058 T+ S T+ S I+ GS + S + ST + S+ + ST + + Sbjct: 337 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGA 396 Query: 1059 KSLSLSTSQSGSTSTSTSTSASVRTSESQSTSGSMSASQSDSMSISTSFSDSTSDSKSAS 1118 S ++ S T+ ST + S + GS + S + S + S Sbjct: 397 DSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQ 456 Query: 1119 TASSESISQSASTSTSGSVSTSTSLSTSNSERTSTSVSDSTSLSTSESDSISESTSTSDS 1178 TA +S + ST + S + S T+ S + S + ST T+ Sbjct: 457 TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGY 516 Query: 1179 ISEAISASESTSISLSESNSTSDSESQSASAFLSESLSESTSESTSESVSSSTSESTSLS 1238 S + +ES I+ S ST+ + S + + S + S T+ S+ T+ S Sbjct: 517 GSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDL 576 Query: 1239 DSTSESGSTSTSLSNSTSGSASISTSTSISESTSTFKSESVSTSLSMSTSTSLSNSTSLS 1298 + S T+ S S+ +G S T++ S T+ + S + S+ T+ S ST+ + Sbjct: 577 TAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGA 636 Query: 1299 TSLSDSTSDSKSDSLSTSMSTSDSISTSKSDSISTSTSLSGSTSESESDSTSSSESKSDS 1358 S + S + S+ T+ ST + S T+ GSTS + +DS+ + S Sbjct: 637 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQ 696 Query: 1359 TSMSISMSQSTSGSTSTSTSTSLSDSTSTSLSLSASMNQSGVDSNSASQSASNSTSTSTS 1418 T+ S+ + GST T+ S S S S + + + S ++ +S+ T+ Sbjct: 697 TAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGY 756 Query: 1419 ESDSQSTSTYTSQSTSQSESTSTSTSLSDSTSISKSTSQSGSTSTSASLSGSESESDSQS 1478 S + + S ST+ + S + S T+ S T+ S ++ S Sbjct: 757 GSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDL 816 Query: 1479 ISTSASESTSESASTSLSDSTSTSNSGSASTSTSLSNSASASESDSSSTSLSDSTSASMQ 1538 + S ST+ + S+ ++ ST +G S T+ S ++ +S T+ STS + Sbjct: 817 TTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGY 876 Query: 1539 SSESDSQSTSASLSDSLSTSTSNRMSTIASLSTSVSTSESGSTSESTSESDSTSTSLSDS 1598 S + S + S T+ ST + S T+ GSTS + ES + S Sbjct: 877 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQ 936 Query: 1599 QSTSRSTSASGSASTSTSTSDSRSTSASTSTSMRTSTSDSQSMSLSTSTSTSMSDSTSLS 1658 ++ +ST +G S+ T+ S T+ STSM S + ST T+ S T+ Sbjct: 937 TASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGY 996 Query: 1659 DSVSDSTSDSTSASTSGSMSVSISLSDSTSTSTSASEVMSASISDSQSMSESVNDSESVS 1718 S + ST + GS + + + S + S+ S + S ++ SV Sbjct: 997 GSTQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVL 1056 Query: 1719 ESNSESDSKSMSGSTSVSDSGSLSVSTSLRKSESVSESSSLSGSQSMSDSVSTSDSSSLS 1778 + S S S+ + GS +++ + ES+ ++G++SM + S ++ Sbjct: 1057 TAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGY 1116 Query: 1779 VSTSLRSSESVSESDSLSDSKSTSGSTSTS 1808 ST + ++SV + + + ST T+ Sbjct: 1117 RSTLISGADSVQMAGERGKLIAGADSTQTA 1146 Score = 52.8 bits (126), Expect = 2e-08 Identities = 229/1007 (22%), Positives = 395/1007 (39%), Gaps = 10/1007 (0%) Query: 1163 TSESDSISESTSTSDSISEAISASESTSISLSESNSTSDSESQSASAFLSESLSESTSES 1222 TS I + + +E + S ++ ES S +++ Sbjct: 99 TSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQT 158 Query: 1223 TSESVSSSTSESTSLSDSTSESGSTSTSLSNSTSGSASISTSTSISESTSTFKSESVSTS 1282 + ST T S + GST T+ +ST + ST T+ ++ST S T+ Sbjct: 159 IEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTA 218 Query: 1283 LSMSTSTSLSNSTSLSTSLSDSTSDSKSDSLSTSMSTSDSISTSKSDSISTSTSLSGSTS 1342 S+ + ST SD T+ S + S+ + S + S+ +G S Sbjct: 219 GEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGS 278 Query: 1343 ESESDSTSSSESKSDSTSMSISMSQSTSGSTSTSTSTSLSDSTSTSLSLSASMNQSGVDS 1402 + S + ST + + S +G ST T+ S T+ S + S + + Sbjct: 279 TQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTA 338 Query: 1403 NSASQSASNSTSTSTSESDSQSTSTYTSQSTSQSESTSTSTSLSDSTSISKSTSQSGSTS 1462 S + S+ + S T+ S T+ ST T+ SD T+ GST Sbjct: 339 GYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTA------GYGSTG 392 Query: 1463 TSASLSGSESESDSQSISTSASESTSESASTSLSDSTSTSNSGSASTSTSLSNSASASES 1522 T+ + S + S + S T+ ST + S +G ST T+ +S+ + Sbjct: 393 TAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGY 452 Query: 1523 DSSSTSLSDSTSASMQSSESDSQSTSASLSDSLSTSTSNRMSTIASLSTSVSTSESGSTS 1582 S+ T+ DS+ + S +Q S + STST+ S++ ++ ST +G S Sbjct: 453 GSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSL--IAGYGSTQTAGYGS 510 Query: 1583 ESTSESDSTSTSLSDSQSTSRSTSASGSASTSTSTSDSRSTSASTSTSMRTSTSDSQSMS 1642 T+ ST T+ ++S + S S + + S+ + ST ++ S+ T+ S + Sbjct: 511 TLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTA 570 Query: 1643 LSTSTSTSMSDSTSLSDSVSDSTSDSTSASTSGSMSVSISLSDSTSTSTSASEVMSASIS 1702 S T+ ST + S S + S T+ S + ST T+ S + + S Sbjct: 571 REGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGS 630 Query: 1703 DSQSMSESVNDSESVSESNSESDSKSMSGSTSVSDSGSLSVSTSLRKSESVSESSSLSGS 1762 S + ++S + S + +S +G S + S T+ S S + + S + Sbjct: 631 TSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIA 690 Query: 1763 QSMSDSVSTSDSSSLSVSTSLRSSESVSESDSLSDSKSTSGSTSTSTSGSLSTSTSLSGS 1822 S + +S + S ++++ S+ S S ST+G+ S+ +G ST T+ S Sbjct: 691 GYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHS 750 Query: 1823 ESVSESTSLSDSISMSDSTSTSDSDSLSGSISLSGSTSLSTSDSLSDSKSLSSSQSMSGS 1882 + S + S T+ S S +G+ S + ST + S + S + Sbjct: 751 SLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTA 810 Query: 1883 ESTSTSVSDSQSSSTSNSQFDSMSISASESDSMSTSDSSNISGSNSTSTSLSTSDSMSGS 1942 + S + S+ST+ DS I+ S + +S +G ST T+ SD +G Sbjct: 811 QERSDLTTGYGSTSTAG--ADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGY 868 Query: 1943 VSVSTSTSLSDSISGSTSVSDSSSTSTSTSLSDSMSQSQSTSTSASGSLSTSISTSMSMS 2002 S ST+ S I+G S + S T+ S +Q S +G STS + S Sbjct: 869 GSTSTAGYDSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSL 928 Query: 2003 ASTSSSQSTSVSTSLSTSDSISDSTSISISGSQSTVESESTSDSTSISDSESLSTSDSDS 2062 + S T+ S + S T+ S + S S + S + ST + Sbjct: 929 IAGYGSTQTASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGY 988 Query: 2063 TSTSTSDSTSGSTSTSISESLSTSGSGSTSVSDSTSMSESDSTSVSMSQDKSDSTSISDS 2122 ST T+ S T+ S + GS +T+ +DS+ ++ S+ S + + S Sbjct: 989 QSTLTAGYGSTQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTL 1048 Query: 2123 ESVSTSTSTSLSTSDSTSTSESLSTSMSGSQSISDSTSTSMSGSTST 2169 S S T+ S S S T+ GS I+ S+ ++G ST Sbjct: 1049 ISGLRSVLTAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPEST 1095 Score = 52.1 bits (124), Expect = 3e-08 Identities = 193/856 (22%), Positives = 350/856 (40%), Gaps = 14/856 (1%) Query: 1329 DSISTSTSLSGSTSESESDSTSSSESKSDSTSMSISMSQSTSGSTSTSTSTSLSDSTSTS 1388 S + ++ + + + S + + + + T +T S ST + Sbjct: 97 TKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPT 156 Query: 1389 LSLSASMNQSGVDSNSASQSASNSTSTSTSESDSQSTSTYTSQSTSQSESTSTSTSLSDS 1448 ++ + S + SQ + ST T+ S + Y S T+ ++ST + S Sbjct: 157 QTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQ 216 Query: 1449 TSISKSTSQSGSTSTSASLSGSESESDSQSISTSASEST--SESASTSLSDSTSTSNSGS 1506 T+ +S+ +G ST + GS+ + S T+ +S+ + ST + S+ +G Sbjct: 217 TAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGY 276 Query: 1507 ASTSTSLSNSASASESDSSSTSLSDSTSASMQSSESDSQSTSASLSDSLSTSTSNRMSTI 1566 ST T+ S + S+ T+ +DS+ + S + S + ST T+ + S + Sbjct: 277 GSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDL 336 Query: 1567 ASLSTSVSTSESGST------SESTSESDSTSTSLSDSQSTSRSTSASGSASTSTSTSDS 1620 + S T+ S+ S T+ DS+ T+ S T++ S + ST T+ + Sbjct: 337 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGA 396 Query: 1621 RSTSASTSTSMRTSTSDSQSMSLSTSTSTSMSDSTSLSDSVSDSTSDSTSASTSGSMSVS 1680 S+ + S +T+ +S + ST T+ S + S T+ S+ +G S Sbjct: 397 DSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQ 456 Query: 1681 ISLSDSTSTSTSASEVMSASISDSQSMSESVNDSESVSESNSESDSKSMSGSTSVSDSGS 1740 + DS+ T+ S + SD + S + + S + S +G S +G Sbjct: 457 TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGY 516 Query: 1741 LSVSTSLRKSESVSESSSLSGSQSMSDSVSTSDSSSLSVSTSLRSSESVSESDSLSDSKS 1800 S T+ +S+ ++ S S + + S ++ S+ + S+ ++ S + S Sbjct: 517 GSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDL 576 Query: 1801 TSGSTSTSTSGSLSTSTSLSGSESVSESTSLSDSISMSDSTSTSDSDSLSGSISLSGSTS 1860 T+G ST T+GS S+ + GS + S + S T+ S +G S S + + Sbjct: 577 TAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGA 636 Query: 1861 LST------SDSLSDSKSLSSSQSMSGSESTSTSVSDSQSSSTSNSQFDSMSISASESDS 1914 S+ S + S+ ++ S + S + STS + DS I+ S Sbjct: 637 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQ 696 Query: 1915 MSTSDSSNISGSNSTSTSLSTSDSMSGSVSVSTSTSLSDSISGSTSVSDSSSTSTSTSLS 1974 + +S +G ST T+ SD SG S ST+ + S I+G S +S S+ T+ Sbjct: 697 TAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGY 756 Query: 1975 DSMSQSQSTSTSASGSLSTSISTSMSMSASTSSSQSTSVSTSLSTSDSISDSTSISISGS 2034 S ++ S +G STS + + S + S T+ S+ T+ S T+ S Sbjct: 757 GSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDL 816 Query: 2035 QSTVESESTSDSTSISDSESLSTSDSDSTSTSTSDSTSGSTSTSISESLSTSGSGSTSVS 2094 + S ST+ + S + ST + S T+ S T+ S+ + GS ST+ Sbjct: 817 TTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGY 876 Query: 2095 DSTSMSESDSTSVSMSQDKSDSTSISDSESVSTSTSTSLSTSDSTSTSESLSTSMSGSQS 2154 DS+ ++ ST + + S + S T+ S ST+ ES + GS Sbjct: 877 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQ 936 Query: 2155 ISDSTSTSMSGSTSTS 2170 + ST M+G S+ Sbjct: 937 TASFKSTLMAGYGSSQ 952 Score = 51.3 bits (122), Expect = 5e-08 Identities = 200/886 (22%), Positives = 350/886 (39%), Gaps = 6/886 (0%) Query: 797 KSTSVSLSDSVSASKSLSTSESNSVSSSTSTSLVNSQSVSSSMSGSVSKSTSLSDSISNS 856 ++ + + SA + + ++ V+ + + S V+S + D + Sbjct: 89 RAEVLHVGTKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATI 148 Query: 857 NSTEKSESLSTSTSDSLRTSTSLSDSLSMSTSGSLSKSQSLSTSISGSSSTSASLSDSTS 916 S + + + T + S ++ GS + ST I+G ST + +DST Sbjct: 149 ESGSTQPTQTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTL 208 Query: 917 NAISTSTSLSESASTSDSISISNSIANSQSASTSKSDSQSTSISLSTSDSKSMSTSESLS 976 A ST + S+ + S S T+ S T+ S+ + ST + Sbjct: 209 VAGYGSTQTAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGE 268 Query: 977 DSTSTSGSVSGSLSIAASQSVSTSTSDSMSTSEIVSDSISTSGSLSASDSKSMSVSSSMS 1036 DS+ T+G S + S + S + ++ + S + +S + S Sbjct: 269 DSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQ 328 Query: 1037 TSQSGSTSESLSDSQSTSDSDSKSLSLSTSQSGSTSTSTSTSASVRTSESQSTSGSMSAS 1096 T+Q GS + S T+ DS + + GST T+ S+ S T+ S Sbjct: 329 TAQKGSDLTAGYGSTGTAGDDSSLI----AGYGSTQTAGEDSSLTAGYGSTQTAQKGSDL 384 Query: 1097 QSDSMSISTSFSDSTSDSKSASTASSESISQSASTSTSGSVSTSTSLSTSNSERTSTSVS 1156 + S T+ +DS+ + ST ++ S + S + S T+ T T+ Sbjct: 385 TAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGD 444 Query: 1157 DSTSLSTSESDSISESTSTSDSISEAISASESTSISLSESNSTSDSESQSASAFLSESLS 1216 DS+ ++ S + S+ + + ++ S + STS + +S+ S Sbjct: 445 DSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQ 504 Query: 1217 ESTSESTSESVSSSTSESTSLSDSTSESGSTSTSLSNSTSGSASISTSTSISESTSTFKS 1276 + ST + ST + + SD + GSTST+ +NS+ + ST T+ S T Sbjct: 505 TAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGY 564 Query: 1277 ESVSTSLSMSTSTSLSNSTSLSTSLSDSTSDSKSDSLSTSMSTSDSISTSKSDSISTSTS 1336 S T+ S T+ ST + S S + S ++ S+ + S + S Sbjct: 565 GSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVL 624 Query: 1337 LSGSTSESESDSTSSSESKSDSTSMSISMSQSTSGSTSTSTSTSLSDSTSTSLSLSASMN 1396 +G S S + + SS + ST + S T+G ST T+ SD T+ S S + Sbjct: 625 TTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGA 684 Query: 1397 QSGVDSNSASQSASNSTSTSTSESDSQSTSTYTSQSTSQSESTSTSTSLSDSTSISKSTS 1456 S + + S + S T+ S T+ S TS STST+ + S + ST Sbjct: 685 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQ 744 Query: 1457 QSGSTSTSASLSGSESESDSQSISTS--ASESTSESASTSLSDSTSTSNSGSASTSTSLS 1514 + S+ + GS + QS+ T+ S ST+ + S+ ++ ST +G S T+ Sbjct: 745 TASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGY 804 Query: 1515 NSASASESDSSSTSLSDSTSASMQSSESDSQSTSASLSDSLSTSTSNRMSTIASLSTSVS 1574 S ++ S T+ STS + S + S + S T+ ST + S Sbjct: 805 GSTQTAQERSDLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDL 864 Query: 1575 TSESGSTSESTSESDSTSTSLSDSQSTSRSTSASGSASTSTSTSDSRSTSASTSTSMRTS 1634 T+ GSTS + +S + S + S +G ST T+ +S T+ STS Sbjct: 865 TTGYGSTSTAGYDSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGY 924 Query: 1635 TSDSQSMSLSTSTSTSMSDSTSLSDSVSDSTSDSTSASTSGSMSVS 1680 S + ST T++ S + S + S+ + GS S++ Sbjct: 925 ESSLIAGYGSTQTASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMA 970 Score = 49.0 bits (116), Expect = 3e-07 Identities = 206/894 (23%), Positives = 361/894 (40%), Gaps = 6/894 (0%) Query: 733 TDASGNKTTTTFKYEVTRNSMSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVSTS 792 T G+ T + T + S ++ GSTQ + ST A S T+ GS + + Sbjct: 281 TAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGY 340 Query: 793 ASTSKSTSVSLSDSVSASKSLSTSESNSVSSSTSTSLVNSQSVSSSMSGSVSKSTSLSDS 852 ST + S + S + +S+ + ST S ++ GS + + S Sbjct: 341 GSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSL 400 Query: 853 ISNSNSTEKSESLSTSTSDSLRTSTSLSDSLSMSTSGSLSKSQSLSTSISGSSSTSASLS 912 I+ ST+ + ST T+ T T+ S + GS + S+ I+G ST + Sbjct: 401 IAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGE 460 Query: 913 DSTSNAISTSTSLSESASTSDSISISNSIANSQSA------STSKSDSQSTSISLSTSDS 966 DS+ A ST ++ S + S S A +S+ ST + ST + S Sbjct: 461 DSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQ 520 Query: 967 KSMSTSESLSDSTSTSGSVSGSLSIAASQSVSTSTSDSMSTSEIVSDSISTSGSLSASDS 1026 + + S+ ++ STS + + S IA S T++ +S+ T+ S + GS + Sbjct: 521 TAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGY 580 Query: 1027 KSMSVSSSMSTSQSGSTSESLSDSQSTSDSDSKSLSLSTSQSGSTSTSTSTSASVRTSES 1086 S + S S+ +G S + S+ + S + QS T+ STS + S Sbjct: 581 GSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSL 640 Query: 1087 QSTSGSMSASQSDSMSISTSFSDSTSDSKSASTASSESISQSASTSTSGSVSTSTSLSTS 1146 + GS + +S+ + S T+ S TA S S + + S+ + ST + Sbjct: 641 IAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGY 700 Query: 1147 NSERTSTSVSDSTSLSTSESDSISESTSTSDSISEAISASESTSISLSESNSTSDSESQS 1206 NS T+ S T+ S+ S STST+ + S I+ ST + S+ T+ S Sbjct: 701 NSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQ 760 Query: 1207 ASAFLSESLSESTSESTSESVSSSTSESTSLSDSTSESGSTSTSLSNSTSGSASISTSTS 1266 + S + S ST+ + SS + S + S T+ S T+ S T+ Sbjct: 761 TAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGY 820 Query: 1267 ISESTSTFKSESVSTSLSMSTSTSLSNSTSLSTSLSDSTSDSKSDSLSTSMSTSDSISTS 1326 S ST+ S ++ S T+ S T+ S + +S + S ST+ S+ Sbjct: 821 GSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSL 880 Query: 1327 KSDSISTSTSLSGSTSESESDSTSSSESKSDSTSMSISMSQSTSGSTSTSTSTSLSDSTS 1386 + ST T+ S + ST +++ SD T+ S S + S+ + S ++ Sbjct: 881 IAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASF 940 Query: 1387 TSLSLSASMNQSGVDSNSASQSASNSTSTSTSESDSQSTSTYTSQSTSQSESTSTSTSLS 1446 S ++ + S+ + STS + +S + T + QS T+ S Sbjct: 941 KSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQ 1000 Query: 1447 DSTSISKSTSQSGSTSTSASLSGSESESDSQSISTSASESTSESASTSLSDSTSTSNSGS 1506 + S T+ GST+T+ + S + S S S T+ ST +S S +G Sbjct: 1001 TAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVLTAGY 1060 Query: 1507 ASTSTSLSNSASASESDSSSTSLSDSTSASMQSSESDSQSTSASLSDSLSTSTSNRMSTI 1566 S+ S S+ + S+ + S+ + S + + S ++ S+ T+ ST+ Sbjct: 1061 GSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGYRSTL 1120 Query: 1567 ASLSTSVSTSESGSTSESTSESDSTSTSLSDSQSTSRSTSASGSASTSTSTSDS 1620 S + SV + + ++S T+ S + + S +G S T+ +D Sbjct: 1121 ISGADSVQMAGERGKLIAGADSTQTAGDRSKLLAGNNSYLTAGDRSKLTAGNDC 1174 Score = 47.8 bits (113), Expect = 6e-07 Identities = 241/1091 (22%), Positives = 433/1091 (39%), Gaps = 10/1091 (0%) Query: 907 TSASLSDSTSNAISTSTSLSESASTSDSISISNSIANSQSASTSKSDSQSTSISLSTSDS 966 TSA A + + ++ S ++ + N T D+ S S + + Sbjct: 99 TSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQT 158 Query: 967 KSMSTSESLSDSTSTSGSVSGSLSIAASQSVSTSTSDSMSTSEIVSDSISTSGSLSASDS 1026 ++T S T S ++G S + ST + ST +DS +G S + Sbjct: 159 IEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTA 218 Query: 1027 KSMSVSSSMSTSQSGSTSESLSDSQSTSDSDSKSLSLSTSQSGSTSTSTSTSASVRTSES 1086 S + S S + S + S + GST T+ S+ S Sbjct: 219 GEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGS 278 Query: 1087 QSTSGSMSASQSDSMSISTSFSDSTSDSKSASTASSESISQSASTSTSGSVSTSTSLSTS 1146 T+ S + S T+ +DS+ + ST ++ S + S + S T+ Sbjct: 279 TQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTA 338 Query: 1147 NSERTSTSVSDSTSLSTSESDSISESTSTSDSISEAISASESTSISLSESNSTSDSESQS 1206 T T+ DS+ ++ S + S+ + + ++ S + ST + + S Sbjct: 339 GYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADS 398 Query: 1207 ASAFLSESLSESTSESTSESVSSSTSESTSLSDSTSESGSTSTSLSNSTSGSASISTSTS 1266 + S + EST + ST + SD T+ GST T+ +S+ + ST T+ Sbjct: 399 SLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTA 458 Query: 1267 ISESTSTFKSESVSTSLSMSTSTSLSNSTSLSTSLSDSTSDSKSDSLSTSMS--TSDSIS 1324 +S+ T S T+ S T+ STS + S + S + S T+ S Sbjct: 459 GEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGS 518 Query: 1325 TSKSDSISTSTSLSGSTSESESDSTSSSESKSDSTSMSISMSQSTSGSTSTS------TS 1378 T + + S + GSTS + ++S+ + S T+ S+ + GST T+ T+ Sbjct: 519 TQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTA 578 Query: 1379 TSLSDSTSTSLSLSASMNQSGVDSNSASQSASNSTSTSTSESDSQSTSTYTSQSTSQSES 1438 S T+ S S + S ++ S + ST T+ S T+ Y S ST+ ++S Sbjct: 579 GYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADS 638 Query: 1439 TSTSTSLSDSTSISKSTSQSGSTSTSASLSGSESESDSQSISTSASESTSESASTSLSDS 1498 + + S T+ S +G ST + GS+ + S ST+ ++S+ + S + Sbjct: 639 SLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTA 698 Query: 1499 TSTSNSGSASTSTSLSNSASASESDSSSTSLSDSTSASMQSSESDSQSTSASLSDSLSTS 1558 S + ST + S S STS + + S+ + S ++ S + S Sbjct: 699 GYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGS 758 Query: 1559 TSNRMSTIASLSTSVSTSESGSTSESTSESDSTSTSLSDSQSTSRSTSASGSASTSTSTS 1618 T + STS +G+ S + ST T+ S T+ S + S T+ Sbjct: 759 TQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTT 818 Query: 1619 DSRSTSASTSTSMRTSTSDSQSMSLSTSTSTSMSDSTSLSDSVSDSTSDSTSASTSGSMS 1678 STS + + S + S + S T+ ST + SD T+ S ST+G S Sbjct: 819 GYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDS 878 Query: 1679 VSISLSDSTSTSTSASEVMSASISDSQSMSESVNDSESVSESNSESDSKSMSGSTSVSDS 1738 I+ ST T+ S + + S + S + S S + +S ++G S + Sbjct: 879 SLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTA 938 Query: 1739 GSLSVSTSLRKSESVSESSSLSGSQSMSDSVSTSDSSSLSVSTSLRSSESVSESDSLSDS 1798 S + S + S + S S++ DSS ++ S +++ S + S Sbjct: 939 SFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGS 998 Query: 1799 KSTSGSTSTSTSGSLSTSTSLSGSESVSESTSLSDSISMSDSTSTSDSDSLSGSISLSGS 1858 T+ +ST T+G ST+T+ + S ++ S S S T+ S +SG S+ + Sbjct: 999 TQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVLTA 1058 Query: 1859 TSLSTSDSLSDSKSLSSSQSMSGSESTSTSVSDSQSSSTSNSQFDSMSISASESDSMSTS 1918 S+ S S + S + S+ ++ +S+ + ++ SM I+ S + Sbjct: 1059 GYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNR--SMLIAGKGSSQTAGY 1116 Query: 1919 DSSNISGSNSTSTSLSTSDSMSGSVSVSTSTSLSDSISGSTSVSDSSSTSTSTSLSDSMS 1978 S+ ISG++S + ++G+ S T+ S ++G+ S + S T+ +D + Sbjct: 1117 RSTLISGADSVQMAGERGKLIAGADSTQTAGDRSKLLAGNNSYLTAGDRSKLTAGNDCIL 1176 Query: 1979 QSQSTSTSASG 1989 + S +G Sbjct: 1177 MAGDRSKLTAG 1187
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 37.5 bits (87), Expect = 9e-05 Identities = 53/361 (14%), Positives = 121/361 (33%), Gaps = 40/361 (11%) Query: 30 AFFVVFFVYMAMYLIRNNFKAAQPFLKEEIGLSTLELGYIGL---AFSITYGLGKTLLGY 86 V + + LI P L ++ S + G+ +++ +LG Sbjct: 10 ILSTVALDAVGIGLI----MPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 87 FVDGRNTKRIISFLLILSAITVLIMGFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYST 146 D + ++ L +A+ IM + F V+ + ++ G+ G G + + Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMAT--APFLWVLYIGRIVAGITG----ATGAVAGAY 119 Query: 147 ISRWAPRTKRGRYLGFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGI 206 I+ +R R+ GF + G + H F + + L + Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP----FFAAAALNGLNFL 175 Query: 207 ATLFIGKDDPEELGWNRAEEIWEEPVDKENIDSQGMTKWEIFKKYILGNPVIWILCVSNV 266 F+ + + + P+ +E ++ +W V ++ V + Sbjct: 176 TGCFLLPE---------SHKGERRPLRREALNPLASFRWARGMT-----VVAALMAVFFI 221 Query: 267 FVYIVRIGIDNWAPLYVSEHLHFSKGDAVNTIFYFEI-GALVASLLWGYVSDLLKGRRAI 325 + ++ W ++ + H+ ++ F I +L +++ G V+ L RRA+ Sbjct: 222 MQLVGQVPAALWV-IFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRAL 280 Query: 326 VAIGCMFMITFVVLFYTNATSVMMVNISLFALGALIFGPQLLIGVSLTGFVPKNAISVAN 385 + +++L + + + L A G I P +L + + Sbjct: 281 MLGMIADGTGYILLAFATRGWMAFPIMVLLASGG-IGMP------ALQAMLSRQVDEERQ 333 Query: 386 G 386 G Sbjct: 334 G 334
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.6 bits (199), Expect = 2e-19 Identities = 42/169 (24%), Positives = 72/169 (42%), Gaps = 12/169 (7%) Query: 3 KVVICDDERIIREGLKQIIPWGDYHFNTIYTAKDGVEALSLIQQHQPELVITDIRMPRKN 62 +++ DD+ IR L Q + Y + + I +LV+TD+ MP +N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY---DVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GVDLLNDI--ALLDCNVIILSSYDDFEYMKAGIQHHVLDYLLKPVDHAQLEVILGRLVRT 120 DLL I A D V+++S+ + F + DYL KP D L ++G + R Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFD---LTELIGIIGRA 118 Query: 121 LLEQQSQNGRSLASCHDAFQPLLKVEYDDYYVNQIVDQIKQSYQTKVTV 169 L E + + + D PL+ + +I + + QT +T+ Sbjct: 119 LAEPKRRPSKLEDDSQD-GMPLVG---RSAAMQEIYRVLARLMQTDLTL 163
>PF06580#Sensor histidine kinase Length = 349 Score = 147 bits (372), Expect = 6e-42 Identities = 55/226 (24%), Positives = 109/226 (48%), Gaps = 16/226 (7%) Query: 288 YIYDLFESNEQLIHSIEHTERRLRDIQLKEIERQFQPHFLFNTMQTIQYLITLSPKLAQT 347 + + F++ +Q ++ QL ++ Q PHF+FN + I+ LI P A+ Sbjct: 136 FGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKARE 195 Query: 348 VVQQLSQMLRYSLR-TNSHTVELNEELNYIEQYVAIQNIRFDDMIKLHIESSEEARHQTI 406 ++ LS+++RYSLR +N+ V L +EL ++ Y+ + +I+F+D ++ + + + Sbjct: 196 MLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQV 255 Query: 407 GKMMLQPLIENAIKHGRDTESLDITIRLTLARQN--LHVLVCDNGIGMSSSRLQYVRQSL 464 M++Q L+EN IKHG I L + N + + V + G L+ ++S Sbjct: 256 PPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA----LKNTKES- 310 Query: 465 NNDVFDTKHLGLNHLHNKAMIQYGSHARLHIFSKRNQGTLICYKIP 510 GL ++ + + YG+ A++ + K+ + + IP Sbjct: 311 -------TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVL-IP 348
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 32.4 bits (74), Expect = 0.006 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 5/54 (9%) Query: 257 AYLAAIKEQNGAAMSLGRTSTFLDIYAERDLKAGVITESEV-QEIIDHFIMKLR 309 +AA+ A LGRT +I A R +K GVI + V ++++ HFI ++ Sbjct: 50 KSVAAVGHD--AKQMLGRTPG--NIAAIRPMKDGVIADFFVTEKMLQHFIKQVH 99
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.0 bits (72), Expect = 0.009 Identities = 37/215 (17%), Positives = 66/215 (30%), Gaps = 16/215 (7%) Query: 249 ETKQNRPNSITKYDPTKHNFKEKSENKPNFDKLVEETKKAVKEADESWKNKTVKKYEETV 308 E+K N + T N + E K N + + A ++ T K TV Sbjct: 1047 ESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATV 1106 Query: 309 TKSPVVKEEKKVEEPQLPKVGNQQEVKTTAGKAEETTQPVAQPLVKIPQETIYGETVKGP 368 K +E+ KVE + +V + + ET QP A+P TV Sbjct: 1107 EK----EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEP------ARENDPTVNIK 1156 Query: 369 EYPTMENKTLQGEIVQGPDFLTMEQNRPSLSDNYTQPTTPNPILEGLEGSSSKLEIKPQG 428 E + N + Q P T ++++ T T + + + + +P Sbjct: 1157 EPQSQTNT--TADTEQ-PAKETSSNVEQPVTESTTVNTGNSVVENPENTTPA--TTQPTV 1211 Query: 429 TESTLKGIQGESSDIEVKPQATETTEASQYGPRPQ 463 + + V+ A+ Sbjct: 1212 NSESSNKPK-NRHRRSVRSVPHNVEPATTSSNDRS 1245
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 145 bits (366), Expect = 1e-44 Identities = 85/250 (34%), Positives = 136/250 (54%), Gaps = 13/250 (5%) Query: 5 KSALVTGASRGIGRSIALQLAEEGYNV-AVNYAGSKEKAEAVVEEIKAKGVDSFAIQANV 63 K A +TGA++GIG ++A LA +G ++ AV+Y + EK E VV +KA+ + A A+V Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDY--NPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 64 ADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQK 123 D+ + + + + G +D+LVN AG+ R L+ + ++EW+ N GVFN + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 124 ATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVA 183 + M+ +RSG+I+ + S V A Y ++KA + TK ELA I N V+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 184 PGFIVSDMTDAL--SDELKEQML--------TQIPLARFGQDTDIANTVAFLASDKAKYI 233 PG +DM +L + EQ++ T IPL + + +DIA+ V FL S +A +I Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 234 TGQTIHVNGG 243 T + V+GG Sbjct: 247 TMHNLCVDGG 256
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 26.3 bits (58), Expect = 0.012 Identities = 10/42 (23%), Positives = 17/42 (40%), Gaps = 2/42 (4%) Query: 33 GADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINS 74 GA++LD A+ + E P + K+ D F+ Sbjct: 296 GANALDTAKAIKAKLAELQPFFP--QGMKVLYPYDTTPFVQL 335
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 54.7 bits (131), Expect = 2e-09 Identities = 53/326 (16%), Positives = 119/326 (36%), Gaps = 23/326 (7%) Query: 170 KYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRV-EPLKEEAAIAKEYKTLSHQMKHSDI 228 K K +E +K+ + E +E L + + E L+ + + Sbjct: 103 KNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLE- 161 Query: 229 VVTVHDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKG-------KRHQLD 281 ++ N + ++ L+ ++A EA + L + ++ K L+ Sbjct: 162 ----KALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLE 217 Query: 282 NDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLMELLENISNEIS 341 + +L + +A E + K A E Q L + LE N + Sbjct: 218 AEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFST 277 Query: 342 EAQDTYKSLKSKQKELNAVIRELEEQLYVSD----------EAHDEKLEEIKNEYYTLMS 391 K+L++++ L A +LE Q V + +A E ++++ E+ L Sbjct: 278 ADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEE 337 Query: 392 EQSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELSA 451 + + L+ ++ + K +L++ ++ EQ K + ++ +++ + + Sbjct: 338 QNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ 397 Query: 452 VDKEIKNIEKDLTDTKKAQNEYEEKL 477 V+K ++ L +K E EE Sbjct: 398 VEKALEEANSKLAALEKLNKELEESK 423 Score = 53.1 bits (127), Expect = 5e-09 Identities = 31/315 (9%), Positives = 94/315 (29%), Gaps = 18/315 (5%) Query: 177 ESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKTLSHQMKHSDIVVTVHDID 236 E +K + + L L ++ +E + + I Sbjct: 57 ERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQ 116 Query: 237 QYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATE 296 + L++ L A + L + ++ L+ +E + Sbjct: 117 ELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSA 176 Query: 297 AFEKYTGQLNVLEERKKNQSETNARYEEEQENLMELLENISNEISEAQDTYKSLKSKQKE 356 + + LE R+ + ++ + E + L+ + Sbjct: 177 KIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEG 236 Query: 357 LNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEAKKSR 416 ++ + + + ++ L N I+ EA+K+ Sbjct: 237 AMNFSTADSAKI----KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA 292 Query: 417 LDSRLVEVFEQLKDIQGQIKTTKK--------------EYQQTNKELSAVDKEIKNIEKD 462 L++ ++ Q + + ++ ++ E+Q+ ++ + +++ +D Sbjct: 293 LEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRD 352 Query: 463 LTDTKKAQNEYEEKL 477 L +++A+ + E + Sbjct: 353 LDASREAKKQLEAEH 367
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 35.6 bits (82), Expect = 3e-04 Identities = 16/79 (20%), Positives = 29/79 (36%), Gaps = 11/79 (13%) Query: 192 VGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEG- 250 GV GV + L + +L + + I Q + VD+IS S G Sbjct: 101 NGVVGVAPEADL--LIIK--------VLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGG 150 Query: 251 SDPAAVMYDAINAAKNKGV 269 + +++A+ A + Sbjct: 151 PEDVPELHEAVKKAVASQI 169
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 26.0 bits (57), Expect = 0.037 Identities = 11/42 (26%), Positives = 23/42 (54%) Query: 10 LRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVS 51 L +NY + S++ ++ N L+ FY + Y + D +N++ Sbjct: 334 LNLNYFCQSFNSIIPDRFSNALKHFYRKQYYTMDYTDNYNIN 375
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 1e-04 Identities = 31/185 (16%), Positives = 68/185 (36%), Gaps = 35/185 (18%) Query: 277 IEEMNRIIKLVEELLELTKGDVNDISSEAQTVHINDE---IRSRIHSLKQLHPD-YQFDT 332 +E+ + +++ L EL + + S A+ V + DE + S + D QF+ Sbjct: 187 LEDPTKAREMLTSLSELMRYSLRY--SNARQVSLADELTVVDSYLQLASIQFEDRLQFEN 244 Query: 333 DLTSKNLEIKMKPHQFEQLFLIFIDNAIKYDVKNKK----IKVKTRLKNKQKIIEITDHG 388 + +++++ P L ++N IK+ + I +K N +E+ + G Sbjct: 245 QINPAIMDVQVPPM----LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG 300 Query: 389 IGIPEEDQDFIFDRFYRVDKSRSRSQGGNGLGLSIAQKIIQL---NGGSIKIKSEINKGT 445 + ++ G GL ++ +Q+ IK+ + K Sbjct: 301 SLALKNTKE------------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN 342 Query: 446 TFKII 450 +I Sbjct: 343 AMVLI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.6 bits (230), Expect = 5e-24 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 4/125 (3%) Query: 2 TQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGLDKALSHYYDLIILDLMLPSINGL 61 IL+ +D+ + L L+ Y+V + + DL++ D+++P N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EICRKIRQQQS-TPIIIITAKSDTYDKVAGLDYGADDYIVKPFDIEELLARIRAIL---R 117 ++ +I++ + P+++++A++ + + GA DY+ KPFD+ EL+ I L + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 118 RQPQK 122 R+P K Sbjct: 124 RRPSK 128
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.2 bits (73), Expect = 5e-04 Identities = 33/140 (23%), Positives = 54/140 (38%), Gaps = 19/140 (13%) Query: 30 EQWDDQYPLLEHFEEDIAKDYLYVLEENDKIYGFIVVDQDQAEWYDDIDWPVNREGAFVI 89 +Q++D + + EE+ +LY LE + G I + N G +I Sbjct: 48 KQYEDDDMDVSYVEEEGKAAFLYYLE--NNCIGRIKIRS-------------NWNGYALI 92 Query: 90 HRLTGSKEY--KGAATELFNYVIDVVKARGAEVILTDTFALNKPAQGLFAKFGFHKVGEQ 147 + +K+Y KG T L + I+ K ++ +T +N A +AK F Sbjct: 93 EDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVD 152 Query: 148 LMEYP--PYDKGEPFYAYYK 165 M Y P + YYK Sbjct: 153 TMLYSNFPTANEIAIFWYYK 172
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 25.3 bits (55), Expect = 0.022 Identities = 10/25 (40%), Positives = 15/25 (60%) Query: 15 GRHDDKGRLAEEIFDDLAFPKHDDD 39 G +DK LA+ F D+AF + +D Sbjct: 866 GGKEDKLSLADIDFRDVAFKREGND 890
>PF03309#Bvg accessory factor Length = 271 Score = 29.7 bits (67), Expect = 0.012 Identities = 32/154 (20%), Positives = 51/154 (33%), Gaps = 37/154 (24%) Query: 5 ILAADVGGTTCKLGIFTPELEQ---LHKWSIHTD---TSDSTGYTLLKGIYDSFVEKVNE 58 +LA DV T +G+ + + + +W I T+ T+D + G+ Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELA-LTIDGLI--------- 51 Query: 59 NNYNFSNVLGVGIG--VPGPVDFEKGTVNGAVNLYWPE------KVNVREIFEQFVDCPV 110 + + G VP V E V + YWP + VR VD P Sbjct: 52 -GDDAERLTGASGLSTVP-SVLHE---VRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPK 106 Query: 111 YVDND--ANIAALGEKHKGAGEGADDVVAITLGT 142 V D N A K+ + + G+ Sbjct: 107 EVGADRIVNCLAAYHKYGT------AAIVVDFGS 134
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.3 bits (76), Expect = 0.002 Identities = 29/170 (17%), Positives = 54/170 (31%), Gaps = 51/170 (30%) Query: 241 MLTVYFIAGLFGN--------FVSLSFNTTTISVGASGAIFGLIGSIFAMMY---VSKTF 289 ++ V+FI L G F F+ ++G S A FG++ S+ M V+ Sbjct: 215 LMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARL 274 Query: 290 NKK----------MLGQLLIA-----------LVILVGVSLFMS------NINIVAHIGG 322 ++ G +L+A +V+L + M + + G Sbjct: 275 GERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQG 334 Query: 323 FIGGLLITL-----------IGYYYKVNRNIF--WILLIGMLVIFIALQI 359 + G L L Y + + W + G + + L Sbjct: 335 QLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPA 384
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 108 bits (270), Expect = 2e-30 Identities = 54/227 (23%), Positives = 98/227 (43%), Gaps = 37/227 (16%) Query: 30 VGNLRNFYTKHDYIDLKGVTDKNLPIANQLEFS------TGTNDLISESNNWDEISKFKG 83 +GN++ Y H K + +A+ L ++ + + +E N D K+K Sbjct: 48 MGNMKYLYDDHYVSATKVKSVDKF-LAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKD 106 Query: 84 KKLDIFGIDY-------------NGPCKSKYMYGGATL-SGQYLNSARKIPINLWVNGKH 129 + +D++G +Y MYGG T G + ++ + + V Sbjct: 107 EVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENK 166 Query: 130 KTISTDKIATNKKLVTAQEIDVKLRRYLQEEYNIYGHNNTGKGKEYGYKSKFYSGFNNGK 189 + + ++ T+KK VTAQE+D+K R +L + N+Y N+ + G Sbjct: 167 RNTISFEVQTDKKSVTAQELDIKARNFLINKKNLY-EFNSSP-------------YETGY 212 Query: 190 VLFHLNNEKSFSYDLF-YTGDGLPVS-FLKIYEDNKIIESEKFHLDV 234 + F NN +F YD+ GD S +L +Y DNK ++S+ ++V Sbjct: 213 IKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEV 259
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 123 bits (310), Expect = 2e-36 Identities = 64/231 (27%), Positives = 111/231 (48%), Gaps = 36/231 (15%) Query: 28 NLRNYYGSYPIEDHQSINPENNHLSHQLVFSMDNST------VTAEFKNVDDVKKFKNHA 81 N++ Y + + + + L+H L++++ + V E N D KK+K+ Sbjct: 50 NMKYLYDDHYVS-ATKVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKDEV 108 Query: 82 VDVYGLSYSGYCLKNKY------------IYGGVTLA-GDYLEKSRRIPINLWVNGEHQT 128 VDVYG +Y C + +YGG+T G++ + + + V + Sbjct: 109 VDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRN 168 Query: 129 ISTDKVSTNKKLVTAQEIDTKLRRYLQEEYNIYGFNDTNKGRNYGNKSKFSSGFNAGKIL 188 + +V T+KK VTAQE+D K R +L + N+Y FN SS + G I Sbjct: 169 TISFEVQTDKKSVTAQELDIKARNFLINKKNLYEFN--------------SSPYETGYIK 214 Query: 189 FHLNDGSSFSYDLFDT-GTGQAES-FLKIYNDNKTVETEKFHLDVEISYKD 237 F N+G++F YD+ G +S +L +YNDNKTV+++ ++V ++ K+ Sbjct: 215 FIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEVHLTTKN 265
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 170 bits (433), Expect = 1e-54 Identities = 91/262 (34%), Positives = 136/262 (51%), Gaps = 20/262 (7%) Query: 5 LLLILNLIAICSVNNAYANEE-DPKIESLCKKSSVDPIALHNINDDYINNRFTTVKSIVS 63 ++LI LI + S N A + DP + L K S + N+ Y ++ + K V Sbjct: 10 VILIFALILVISTPNVLAESQPDPMPDDLHKSSEFTG-TMGNMKYLYDDHYVSATK--VK 66 Query: 64 TTEKFLDFDLLFKSINWLDGISAEFKDLKVEFSSSAISKEFLGKTVDIYGVYYKAHCH-- 121 + +KFL DL++ D + +K E + ++K++ + VD+YG Y +C+ Sbjct: 67 SVDKFLAHDLIYNI---SDKKLKNYDKVKTELLNEDLAKKYKDEVVDVYGSNYYVNCYFS 123 Query: 122 -----GEHQVDTACTYGGVTPHENNKLSEP--KNIGVAVYKDNVNVNTFIVTTDKKKVTA 174 G+ C YGG+T HE N +N+ V VY++ N +F V TDKK VTA Sbjct: 124 SKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTA 183 Query: 175 QELDIKVRTKLNNAYKLYDRMTSDVQKGYIKFHSHSEHKESFYYDLFYIKGNLPDQ--YL 232 QELDIK R L N LY+ +S + GYIKF ++ +F+YD+ G+ DQ YL Sbjct: 184 QELDIKARNFLINKKNLYEFNSSPYETGYIKFIENNG--NTFWYDMMPAPGDKFDQSKYL 241 Query: 233 QIYNDNKTIDSSDYHIDVYLFT 254 +YNDNKT+DS I+V+L T Sbjct: 242 MMYNDNKTVDSKSVKIEVHLTT 263
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 96.2 bits (239), Expect = 5e-25 Identities = 64/257 (24%), Positives = 107/257 (41%), Gaps = 24/257 (9%) Query: 53 DAKRIVVLEYSFADALAALDVKPVGIADDGKKKRIIK--PVREKIGDYTSVGTRKQPNLE 110 D RIV LE+ + L AL + P G+AD + + P+ + + D VG R +PNLE Sbjct: 34 DPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVID---VGLRTEPNLE 90 Query: 111 EISKLKPDLIIADSSRHKGINKELNKIAPTLSLKSFDGDYKQNI--NSFKTIAKALNKEK 168 ++++KP ++ S+ + + L +IAP DG + S +A LN + Sbjct: 91 LLTEMKPSFMVW-SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQS 149 Query: 169 EGEKRLAEHDKLINKYKDEIKFDRNQKVLPAVV---AKAGLLAHPNYSYVGQFLNELGFK 225 E LA+++ I K R + L + L+ PN S + L+E G Sbjct: 150 AAETHLAQYEDFIRSMKPRF-VKRGARPLLLTTLIDPRHMLVFGPN-SLFQEILDEYGIP 207 Query: 226 NALSDDVTKGLSKYLKGPYLQLDTEHLADLNPERMIIMTDHAKKDSAEFKKLQEDATWKK 285 NA +G + + + + LA ++ DH +S + L W+ Sbjct: 208 NAW-----QGETNFWG--STAVSIDRLAAYKDVDVLCF-DHD--NSKDMDALMATPLWQA 257 Query: 286 LNAVKNNRVDIVDRDVW 302 + V+ R V VW Sbjct: 258 MPFVRAGRFQRVP-AVW 273
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 39.4 bits (92), Expect = 1e-05 Identities = 59/325 (18%), Positives = 119/325 (36%), Gaps = 33/325 (10%) Query: 4 VNINISKIKYNAKVLQTVFQSKNIQFTPVIKCIAGDRTIVESLKALG-INHVAESRLDNI 62 ++++ +K N +++ + + + V+K A I A+G + A L+ Sbjct: 7 ASLDLQALKQNLSIVRQA--ATHARVWSVVKANAYGHGIERIWSAIGATDGFALLNLEEA 64 Query: 63 ISIADQDLTYTLLRTPAKKEISDMIEKVDMSIQTELSTIHQINEVAEV-LGKKHKILLMV 121 I++ ++ +L D+ + T + + Q+ + L I L V Sbjct: 65 ITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKV 124 Query: 122 DWKDGREGVLTYDVLDYIKEIIHLKNIHFVGLAFNFMCFKSDAPSDDDIFMINRFVSAVE 181 + R G VL +++ + N+ + L +F ++ P D + R A E Sbjct: 125 NSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAE--AEHP-DGISGAMARIEQAAE 181 Query: 182 REIGYRLKIISGGNSSMLPQLLYNDLGKINELRIGETLFRGVDTTTNQAIAML-YQDAIT 240 + R + + + P+ ++ +R G L+ + + IA + +T Sbjct: 182 -GLECRRSLSNSAATLWHPEAHFD------WVRPGIILYGASPSGQWRDIANTGLRPVMT 234 Query: 241 LEAEILEIK-----PRVN-----TQTHESFLQAIVDIGYLD---TKVDNISPM---DQHI 284 L +EI+ ++ RV T E + IV GY D +P+ Sbjct: 235 LSSEIIGVQTLKAGERVGYGGRYTARDEQRI-GIVAAGYADGYPRHAPTGTPVLVDGVRT 293 Query: 285 NILGA-SSDHLMLDLNGQGHYQVGD 308 +G S D L +DL +G Sbjct: 294 MTVGTVSMDMLAVDLTPCPQAGIGT 318
>PF04183#IucA / IucC family Length = 580 Score = 258 bits (661), Expect = 1e-80 Identities = 92/456 (20%), Positives = 176/456 (38%), Gaps = 56/456 (12%) Query: 166 EGHPTHPLTKTKLPLTMEEVRAYAPEFEKEIPLQIMMIEKDHVVCTAMDGND--QFIIDE 223 GHP K + E + YAPE+ L + ++++H++ + D Q + Sbjct: 134 SGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLTAA 193 Query: 224 IIPEYYNQIRVFLKSLGLKSEDYRAILVHPWQYDHTIGKYFEAWIAKKILIPT-PFTILS 282 + P+ + + + GL ++ + VHPWQ+ I F A A+ ++ F Sbjct: 194 MDPQEFARFSQVWQENGL-DHNWLPLPVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQW 252 Query: 283 KATLSFRTMSLIDKP--YHVKLPVDAQATSAVRTVSTVTTVDGPKLSYALQN-------- 332 A S RT++ + +KLP+ TS R + GP S LQ Sbjct: 253 LAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATL 312 Query: 333 ------MLNQYPGFKVAMEPFGEYANVDKDRARQLACIIRQKPE--IDGKGATVVSASLV 384 +L + V+ E + A L I R+ P + + V+ A+L+ Sbjct: 313 VQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLM 372 Query: 385 NKNPIDQKVIVDSYLEWLNQGITKESITTFIERYAQALIPPLIAFIQNYGIALEAHMQNT 444 + +Q + +Y++ G+ E+ ++ + + ++ PL + YG+AL AH QN Sbjct: 373 ECDENNQPLA-GAYID--RSGLDAET---WLTQLFRVVVVPLYHLLCRYGVALIAHGQNI 426 Query: 445 VVNLGPHFDIQFLVRDLGGS-RI------DLETLQHRVSDI--KITNDSLIADSIDAVIA 495 + + + L++D G R+ ++++L V D+ +++ D LI D Sbjct: 427 TLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFV 486 Query: 496 KFQHAVIQNQMAELIHHFNQYDCVEETELFNIVQQVVA--HAINPTLPHANELKDILFGP 553 I V E + ++ V++ +P + L LF P Sbjct: 487 TV---------LRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFS-LFRP 536 Query: 554 TITVKALLNMRM-----ENKVKQYLNI--ELDNPIK 582 I L +++ + + N +L NP+ Sbjct: 537 QIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLW 572
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.7 bits (98), Expect = 3e-06 Identities = 53/340 (15%), Positives = 106/340 (31%), Gaps = 26/340 (7%) Query: 6 FSSSFLLFLGNWIGQIGLNWFVLTTYHN--------AVYLGIVNFCRLVPILLLSVWAGA 57 S+ L +G IGL VL + GI+ + + GA Sbjct: 11 LSTVALDAVG-----IGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 58 IADKYDKGRLLRITISSSFLVTAILCVLTYSFTAIPISVIIIYAT-LRGILSAVETPLRQ 116 ++D++ + R + S A+ Y+ A + ++Y + ++ + Sbjct: 66 LSDRFGR----RPVLLVSLAGAAV----DYAIMATAPFLWVLYIGRIVAGITGATGAVAG 117 Query: 117 AILPDLSDKISTTQAVSFHSFIINICRSIGPAIAGVILAVYHAPTTFLAQA--ICYFIAA 174 A + D++D + F S GP + G++ F A A F+ Sbjct: 118 AYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTG 177 Query: 175 LLCLPLHFKVTKIPEDATRYMPLKVIIDYFKLHMEGRQIFITSLLIMATGFSYTTLLPVL 234 LP K + P PL + + + ++ G L + Sbjct: 178 CFLLPESHKGERRPLRREALNPLASFRWARGMTVVA-ALMAVFFIMQLVGQVPAALWVIF 236 Query: 235 TNKVFPGKSEIFGIAMTMCAIGGIIATLVL-PKVLKYIGMVNMYYLSSLLFGIALLGVVF 293 F + GI++ I +A ++ V +G L + G + + F Sbjct: 237 GEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAF 296 Query: 294 HNIVIMFICITLIGLFSQWARTTNRVYFQNNVKDYERGKV 333 M I ++ + V + +G++ Sbjct: 297 ATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQL 336 Score = 30.6 bits (69), Expect = 0.012 Identities = 37/180 (20%), Positives = 71/180 (39%), Gaps = 21/180 (11%) Query: 10 FLLFLGNWIGQIGLNWFVLTTYH----NAVYLGI-VNFCRLVPILLLSVWAGAIADKYDK 64 + F+ +GQ+ +V+ +A +GI + ++ L ++ G +A + + Sbjct: 217 AVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGE 276 Query: 65 GRLLRITISSSFLVTAILCVLTYSFTAIPISVIIIYATLRGILSAVETPLRQAILPDLSD 124 R L + + + +L T + A PI V++ + P QA+L D Sbjct: 277 RRALMLGMIADGTGYILLAFATRGWMAFPIMVLLA-------SGGIGMPALQAMLSRQVD 329 Query: 125 KISTTQAVSFHSFIINICRSIGPAIAGVILAVYHAPT----TFLAQAICYFIAALLCLPL 180 + Q + + ++ +GP + I A T ++A A Y LLCLP Sbjct: 330 EERQGQLQGSLAALTSLTSIVGPLLFTAIYA-ASITTWNGWAWIAGAALY----LLCLPA 384
>PF04183#IucA / IucC family Length = 580 Score = 270 bits (692), Expect = 2e-84 Identities = 93/475 (19%), Positives = 181/475 (38%), Gaps = 45/475 (9%) Query: 195 SEQAVIEGHPLHPGAKLRKGLNALQTFLYSSEFNQPIKLKIVLIHSKLSRTMSLSKDYDT 254 Q ++ GHP K R+G Y+ E+ +L + + + M D + Sbjct: 128 RLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKRE---HMIWRCDNEM 184 Query: 255 TVHQLF-----PDLIKQLENEFTPNFNFNDYHIMIVHPWQLDDVLHSDYQAEVDKELIIE 309 +HQL P + + N +++ + VHPWQ + +D+ A+ + ++ Sbjct: 185 DIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEGRMVS 244 Query: 310 AKHTLD-YYAGLSFRTLVPKYPAMSPHIKLSTNVHITGEIRTLSEQTTHNGPLMTRILND 368 D + A S RTL IKL ++ T R + + GPL +R L Sbjct: 245 LGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQ 304 Query: 369 ILEKDVIFKSYASTIIDEVAGIHFYNEQDEVDYQTER--SEQLGTLFRKNIYQMIPQEVT 426 + D + I+ E A + +E + E LG ++R+N + + + + Sbjct: 305 VFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDES 364 Query: 427 PMIPSSLVATYPFNNESPIVTLIKRYQSAASLSDFESSAKSWIETYSKALLGLVIPLVTK 486 P++ ++L+ N P+ A + A++W+ + ++ + L+ + Sbjct: 365 PVLMATLMECDE--NNQPLA--------GAYIDRSGLDAETWLTQLFRVVVVPLYHLLCR 414 Query: 487 YGIALEAHLQNAIATFRKDGLLDTMYIRDFEG-LRIDKAQLNEMGYSTSHFHEKSRILTD 545 YG+AL AH QN I K+G+ + ++DF+G +R+ K + EM S E + + Sbjct: 415 YGVALIAHGQN-ITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMD---SLPQEVRDVTSR 470 Query: 546 SKTSVFNKAFYSTVQNHLGELILTISKASNDSNLERHMWYIVRDVLDNIFDQLVLSTHKS 605 + + I + ER + ++ VL + + H Sbjct: 471 LSADYLIHDLQTGHFVTVLRFISPLMVRLGVP--ERRFYQLLAAVLSDYMKK-----HPQ 523 Query: 606 NQVNENRINEIKDTMFAPFIDYKCVTTMRLE----DEAHHY--TYIK-VNNPLYR 653 + +F P I + ++L D Y++ + NPL+ Sbjct: 524 MSERFALFS-----LFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLWL 573
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 28.7 bits (64), Expect = 0.012 Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 5/43 (11%) Query: 99 VDLKVILEYGE-----SAPKIFRKVTELVKEQVKYITGLDVVE 136 D K+ +YG S P FR + +V EQV G +++E Sbjct: 495 TDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLE 537
>PF06438#Heme acquisition protein HasAp Length = 205 Score = 26.5 bits (58), Expect = 0.046 Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 2/28 (7%) Query: 60 NLAYTLFTLEEHTTY--LSELSLGDVFT 85 +L YTLF+ HT + L ++LGD T Sbjct: 72 DLHYTLFSNPSHTLWGKLDSIALGDTLT 99
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 158 bits (402), Expect = 2e-44 Identities = 92/415 (22%), Positives = 187/415 (45%), Gaps = 16/415 (3%) Query: 140 KILAALLFGMFIAILNQTLLNVALPKINTEFNISASTGQWLMTGFMLVNGILIPITAYLF 199 +IL L F ++LN+ +LNV+LP I +FN ++ W+ T FML I + L Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 200 NKYSYRKLFLVALVLFTIGSLICAISMN-FPIMMVGRVLQAIGAGVLMPLGSIVIITIYP 258 ++ ++L L +++ GS+I + + F ++++ R +Q GA L +V+ P Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 259 PEKRGAAMGTMGIAMILAPAIGPTLSGYIVQNYHWNVMFYGMFIIGIIAILVGFVWFKLY 318 E RG A G +G + + +GP + G I HW+ + +I II + K Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIP-MITIITVPFLMKLLKKE 192 Query: 319 QYTTNPKADIPGIIFSTIGFGALLYGFSEAGNKGWGSVEIETMFAIGIIFIILFVIRELR 378 DI GII ++G + + + ++ ++FV + Sbjct: 193 VRIKGH-FDIKGIILMSVGIVFFMLF---TTSYSIS------FLIVSVLSFLIFVKHIRK 242 Query: 379 MKSPMLNLEVLKFPTFTLTTIINMVVMLSLYGGMILLPIYLQNLRGFSALDSG-LLLLPG 437 + P ++ + K F + + ++ ++ G + ++P ++++ S + G +++ PG Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 438 SLIMGLLGPFAGKLLDTIGLKPLAIFGIAVMTYATWELTKLNMDTP-YMTIMGIYVLRSF 496 ++ + + G G L+D G + G+ ++ + + L T +MTI+ ++VL Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVL--G 360 Query: 497 GMAFIMMPMVTAAINALPGRLASHGNAFLNTMRQLAGSIGTAILVTVMTTQTTQH 551 G++F + T ++L + A G + LN L+ G AI+ +++ Sbjct: 361 GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQ 415
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 59.1 bits (143), Expect = 1e-12 Identities = 26/133 (19%), Positives = 45/133 (33%), Gaps = 13/133 (9%) Query: 87 MDLKMPQKGTIAKLD-GMEGSMVQAGNPIAYAYNLDD-LYVTANIDEKDIKDVEVGKDVD 144 ++ P + +L EG +V + DD L VTA + KDI + VG++ Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAI 387 Query: 145 VTIDGQKAS----IKGKVDSIGKATAASFSLMPSSNSDGNYTKVSQVIPVKITLESEPSK 200 + ++ + + GKV +I G V I + Sbjct: 388 IKVEAFPYTRYGYLVGKVKNINLDAI-------EDQRLGLVFNVIISIEENCLSTGNKNI 440 Query: 201 QVVPGMNAEVKIH 213 + GM +I Sbjct: 441 PLSSGMAVTAEIK 453 Score = 32.5 bits (74), Expect = 0.001 Identities = 17/77 (22%), Positives = 35/77 (45%), Gaps = 2/77 (2%) Query: 9 VITVVVLLAIGIAGFYFWNKTTSYVTTDNAKV--NGDQIKIASPASGQIKSLNVKQGDKL 66 ++ ++ + IA V T N K+ +G +I + +K + VK+G+ + Sbjct: 59 LVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESV 118 Query: 67 DKGDKVATVTVQGQDGE 83 KGD + +T G + + Sbjct: 119 RKGDVLLKLTALGAEAD 135
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 44.6 bits (105), Expect = 4e-08 Identities = 13/69 (18%), Positives = 24/69 (34%) Query: 2 KRQAKIEIQNALVDLMAEYPFQEISTKMICAYCNINRSTFYDYYKDKFDLLDTINSKHKE 61 ++ + I + + L ++ S I + R Y ++KDK DL I + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 62 KFQFLLSAL 70 L Sbjct: 69 NIGELELEY 77
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 65.2 bits (159), Expect = 1e-13 Identities = 69/386 (17%), Positives = 141/386 (36%), Gaps = 16/386 (4%) Query: 15 IIILGSLTAIGALSIDMFLPGLPDIRHDF---QTTTSNAQLTLSMFMIGLAFGNLFAGPI 71 +I++ S A+ A+ I + +P LP + D T++ + L+++ + G + Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 72 SDSTGRRKPLIIAMIIFTLASLGIVFVHNIWLMVALRFLQGVTGGAAAVISRAIASDMYS 131 SD GRR L++++ + + +W++ R + G+TG AV IA D+ Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA-DITD 125 Query: 132 GNELTKFMALLMLVNGIAPVVAPTIGGIILNYSVWRMVFVILTIFGFVMVIGSLLKVPES 191 G+E + + G V P +GG++ +S F + + +PES Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP-HAPFFAAAALNGLNFLTGCFLLPES 184 Query: 192 LTVTNRESSSGLKTMFKNFKILLKTPRFVLPMLIQGMTFVILFTYISASPFII--QKIYG 249 R +F+ + V ++ + L + A+ ++I + + Sbjct: 185 HKGERRPLRREALNPLASFR-WARGMTVVAALMAVFFI-MQLVGQVPAALWVIFGEDRFH 242 Query: 250 MTAIQFSWMFAGIGITLIISSQLTGYLVDFIDSQKLMRGMTMIQIIGVILVTIVLLNHWN 309 A A GI ++ + + ++ R M+ +I I+L Sbjct: 243 WDATTIGISLAAFGILHSLAQ---AMITGPVAARLGERRALMLGMIADGTGYILLAFATR 299 Query: 310 FWILAIGFIILIAPVTGVATLGFTIAMDESSSGRGSSSSLLGLVQFLFGGVASPLVGVKG 369 W+ ++L + G+ L ++ +G L + L + PL+ Sbjct: 300 GWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSL-TSIVGPLLFTAI 358 Query: 370 EDNPIPY---IIIIIATAVILIILQI 392 I I A+ L+ L Sbjct: 359 YAASITTWNGWAWIAGAALYLLCLPA 384
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.014 Identities = 11/21 (52%), Positives = 14/21 (66%) Query: 35 VILNGASGSGKTTLLTILGGL 55 V+L G G GK+TL+ L GL Sbjct: 599 VVLEGTGGIGKSTLINTLVGL 619
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.5 bits (196), Expect = 2e-19 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 1/117 (0%) Query: 5 LVVDDDPRILNYIASHLQTEHIDAYTQPSGEAALKLLEKQRVDIAVVDIMMDGMDGFQLC 64 LV DDD I + L D + + + D+ V D++M + F L Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLL 66 Query: 65 NTLKN-DYDIPVIMLTARDALSDKERAFISGTDDYVTKPFEVKELIFRIRAVLRRYN 120 +K D+PV++++A++ +A G DY+ KPF++ ELI I L Sbjct: 67 PRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 129 bits (327), Expect = 3e-35 Identities = 91/398 (22%), Positives = 177/398 (44%), Gaps = 14/398 (3%) Query: 18 FFGLLNETLLVTALPSIMKDFEISYTQVQWLTTAFLLTNGIVIPLSALVIQRYTTRQVFL 77 FF +LNE +L +LP I DF W+ TAF+LT I + + + +++ L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 78 VGISIFFLGTLLGGLS-PHFATLLVARIIQALGAGIMMPLMMTTILDVFQPHERGKYMGI 136 GI I G+++G + F+ L++AR IQ GA L+M + RGK G+ Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 137 FGLVIGLAPAIGPTLSGYLVEYLNWRSLFHVVAPIAAVTFLIGFKTIKNVGTTIKVPIDF 196 G ++ + +GP + G + Y++W L + P+ + + + IK D Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI--PMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 197 ISVIFSVLGFGGLLYGTSSISEKGFDNPIVLVSMIGGVVLVALFVLRQYRLSTPLLNFAV 256 +I +G + T+S S F +I V+ +FV +++ P ++ + Sbjct: 202 KGIILMSVGIVFFMLFTTSYS-ISF--------LIVSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 257 FKNKQFTVGIIIMGVTMVSMIGSETILPIFVQNLLHRSALDSG-LTLLPGAIVMAFMSMT 315 KN F +G++ G+ ++ G +++P ++++ S + G + + PG + + Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 316 SGALYEKFGPRKLALVGMAIVVITTAYFVVMDEQTSTIMLATVYAIRMVGIALGLIPVMT 375 G L ++ GP + +G+ + ++ + E TS M + + G++ + T Sbjct: 313 GGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFTKTVIST 371 Query: 376 HTMNQLKPEMNAHGSSMTNTVQQIAGSIGTAALITILS 413 + LK + G S+ N ++ G A + +LS Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 427 bits (1100), Expect = e-154 Identities = 213/312 (68%), Positives = 247/312 (79%), Gaps = 8/312 (2%) Query: 13 MIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGA--EIIKRTQDITSKRLAITQ 70 M+KNKILT TL+V L+APLANP +E +KA N EDIG+G+ EIIKRT+D TS + +TQ Sbjct: 1 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 Query: 71 NIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNV 130 NIQFDFVKDKKYNKDAL++KMQGFISSRTTY + KK ++K M WPFQYNI LKT D V Sbjct: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYV 120 Query: 131 DLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQKNYVTEVESQ 190 LINYLPKNKI+S +VSQ LGYNIGGNFQSAPS+GG+GSFNYSK+ISY Q+NYV+EVE Q Sbjct: 121 SLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQ 180 Query: 191 NSKGVKWGVKANSFVTPNGQVSAYDQYLF-AQDPTGPAARDYFVPDNQLPPLIQSGFNPS 249 NSK V WGVKANSF T +GQ SA+D LF P RDYFVPD++LPPL+QSGFNPS Sbjct: 181 NSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPS 240 Query: 250 FITTLSHERGKGDKSEFEITYGRNMDATYA-----YVTRHRLAVDRKHDAFKNRNVTVKY 304 FI T+SHE+G D SEFEITYGRNMD T+A + L R H+AF NRN TVKY Sbjct: 241 FIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKY 300 Query: 305 EVNWKTHEVKIK 316 EVNWKTHE+K+K Sbjct: 301 EVNWKTHEIKVK 312
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 469 bits (1207), Expect = e-170 Identities = 314/315 (99%), Positives = 314/315 (99%) Query: 1 MLKNKILATTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 MLKNKIL TTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ Sbjct: 1 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 Query: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYV 120 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYV Sbjct: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYV 120 Query: 121 SLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQ 180 SLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQ Sbjct: 121 SLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQ 180 Query: 181 NSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPS 240 NSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPS Sbjct: 181 NSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPS 240 Query: 241 FIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKY 300 FIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKY Sbjct: 241 FIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKY 300 Query: 301 EVNWKTHEIKVKGQN 315 EVNWKTHEIKVKGQN Sbjct: 301 EVNWKTHEIKVKGQN 315
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 383 bits (985), Expect = e-136 Identities = 87/322 (27%), Positives = 160/322 (49%), Gaps = 18/322 (5%) Query: 1 MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQ 60 M NK++ ++++ S+ L + + + K T S+K+ ++Q Sbjct: 1 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 Query: 61 ILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSK-LYWGAKYNVSISSQSNDS 119 + F+F+KDK Y+KD L+LK G I+S N + K + W +YN+ + + ++ Sbjct: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKT-NDKY 119 Query: 120 VNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTL 179 V++++Y PKN+ E V TLGY GG+ + L G NG+ +S++I+Y Q++Y + + Sbjct: 120 VSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGG--NGSFNYSKSISYTQQNYVSEV 177 Query: 180 SRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQM 239 + N K+V WGV+A+ + ++LF+ + S F+ ++ Sbjct: 178 EQQ-NSKSVLWGVKANSFATESGQ-------KSAFDSDLFVGYKPHSKDPRDYFVPDSEL 229 Query: 240 PLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDL-----YQIRWNGFYWAGANYKN 294 P L +S FNP F++ +SH + + S+ +TY R MD+ + Y G N Sbjct: 230 PPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHN 289 Query: 295 -FKTRTFKSTYEIDWENHKVKL 315 F R + YE++W+ H++K+ Sbjct: 290 AFVNRNYTVKYEVNWKTHEIKV 311
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 28.5 bits (63), Expect = 0.047 Identities = 8/47 (17%), Positives = 15/47 (31%), Gaps = 3/47 (6%) Query: 233 GGVILSSND---VKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLIN 276 IL+ N+ L I + + FI+ ++E Sbjct: 59 SSQILNPNETGTFSQSLTKSKEVSINVNFSVGFTSEFIQASVEYGFG 105
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 43.5 bits (102), Expect = 1e-07 Identities = 33/200 (16%), Positives = 64/200 (32%), Gaps = 34/200 (17%) Query: 11 KSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIATLNRATFYAHFTDKEDLLDYT 70 + T+Q ++D L++ ++ +S ++ +I A + R Y HF DK DL Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 71 LSV---TILKDLNDNLSISNVINEKVLRNIFISIASYIKDAAKSCELNSEAFCNKAHQRI 127 + I + + + VLR I I + + L F Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIF------HK 116 Query: 128 NNELEDIFAIM-LENSYPEHQRDIIVNS-------------------ASFLAAGISGLAL 167 + ++ + + + D I + A + ISGL Sbjct: 117 CEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLME 176 Query: 168 HWFNTSQ-----ETADVFID 182 +W Q + A ++ Sbjct: 177 NWLFAPQSFDLKKEARDYVA 196
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 28.2 bits (62), Expect = 0.011 Identities = 14/45 (31%), Positives = 23/45 (51%) Query: 56 FQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGAVVQE 100 F+N Q +N + N I G ++ V+Q+ + KEAG Q+ Sbjct: 291 FKNPENQKVNIDANGNAIPSGELKDDIVEQIAQQAKEAGEVARQQ 335
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 35.5 bits (82), Expect = 2e-04 Identities = 35/138 (25%), Positives = 53/138 (38%), Gaps = 35/138 (25%) Query: 1 MKDILVIGATGKQGNAVVKQLLEDGWYVSAL--------TRNKNNRKLSDIGHPHLSIVE 52 MK LV GA G G V K+LLE G V + K R L + P + Sbjct: 1 MK-YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQAR-LELLAQPGFQFHK 58 Query: 53 GDLSD-----------------NVSLQSAMKGKYGLYSIQ-PIVKDDVSEELRQGMKIIE 94 DL+D + A++ YS++ P D + L + I+E Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVR-----YSLENPHAYADSN--LTGFLNILE 111 Query: 95 IAEQENIQHIVYSTAGGV 112 IQH++Y+++ V Sbjct: 112 GCRHNKIQHLLYASSSSV 129
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.3 bits (151), Expect = 2e-14 Identities = 25/80 (31%), Positives = 44/80 (55%) Query: 1 MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQ 60 +++A+E RQ I ++A +LF ++GV + S+ IAK G+ G +Y HFKDKSDL + + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 RDLDIFITHFKQIKDDYHSN 80 + + + + Sbjct: 65 LSESNIGELELEYQAKFPGD 84
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 71.6 bits (175), Expect = 4e-17 Identities = 48/197 (24%), Positives = 75/197 (38%), Gaps = 18/197 (9%) Query: 3 KIVLITGGNKGLGYASAEALKALGYKVYIGSRND---VRGQQASQKLGVHYVQ--LDVTS 57 KI ITG +G+G A A L + G + N + + + H DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 58 DYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLPPRDVEEVYQTNVFGIVRMMNTF 117 ++ I + G +DIL+N AG+ + L + E + N G+ + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 118 VPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSKSAVTMLTLQYAKGLP- 176 + +V V S P T+ + AY SSK+A M T L Sbjct: 128 SKYMMDRRSGSIVTVGSNPAG-----VPRTSMA-----AYASSKAAAVMFTKCLGLELAE 177 Query: 177 -NMQINAADPGATNTDL 192 N++ N PG+T TD+ Sbjct: 178 YNIRCNIVSPGSTETDM 194
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 50.9 bits (121), Expect = 2e-08 Identities = 36/125 (28%), Positives = 57/125 (45%), Gaps = 14/125 (11%) Query: 508 NVDPVTNRDYSIFGWNNENVVRYGGGSADGDSAVNPK-----DPTPG----PPVDPEPSP 558 N+ PVT+R+ N VV G + G++ V+ + D TPG P P P Sbjct: 277 NMGPVTDRN-----GNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEV 331 Query: 559 DPEPEPTPDPEPSPDPEPEPSPDPDPDSDSDSDSGSDSDSGSDSDSESDSDSDSDSDSDS 618 P P +P P+ +P P+P+PDPD + D++ +D G+ DS + D + Sbjct: 332 SPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRKE 391 Query: 619 DSDSE 623 + E Sbjct: 392 RKEGE 396 Score = 35.1 bits (80), Expect = 0.001 Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 1/63 (1%) Query: 538 DSAVNPK-DPTPGPPVDPEPSPDPEPEPTPDPEPSPDPEPEPSPDPDPDSDSDSDSGSDS 596 + A NP + PG +PEP PD P+ PD + P P+ PD + + Sbjct: 336 NPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRKERKEG 395 Query: 597 DSG 599 + G Sbjct: 396 EDG 398
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 391 bits (1006), Expect = e-139 Identities = 137/314 (43%), Positives = 198/314 (63%), Gaps = 5/314 (1%) Query: 10 MKEKIVIALGGNAIQT--KEATAEAQQTAIRRAMQNLKPLFDSPARIVISHGNGPQIGSL 67 M +++VIALGGNA+Q ++ + E +R+ + + + +VI+HGNGPQ+GSL Sbjct: 1 MGKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSL 60 Query: 68 LIQQAKSNSDT-TPAMPLDTCGAMSQGMIGYWLETEINRILTEMNSDRTVGTIVTRVEVD 126 L+ + PA P+D GAMSQG IGY ++ + L + ++ V TI+T+ VD Sbjct: 61 LLHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVD 120 Query: 127 KDDPRFNNPTKPIGPFYTKEEVEELQKEQPDSVFKEDAGRGYRKVVASPLPQSILEHQLI 186 K+DP F NPTKP+GPFY +E + L +E + KED+GRG+R+VV SP P+ +E + I Sbjct: 121 KNDPAFQNPTKPVGPFYDEETAKRLARE-KGWIVKEDSGRGWRRVVPSPDPKGHVEAETI 179 Query: 187 RTLADGKNIVIACGGGGIPVIKKENTYEGVEAVIDKDFASEKLATLIEADTLMILTNVEN 246 + L + IVIA GGGG+PVI ++ +GVEAVIDKD A EKLA + AD MILT+V Sbjct: 180 KKLVERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNG 239 Query: 247 VFINFNEPNQQQIDDIDVATLKKYAAQGKFAEGSMLPKIEAAIRFVESGENKKVIITNLE 306 + + +Q + ++ V L+KY +G F GSM PK+ AAIRF+E G ++ II +LE Sbjct: 240 AALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWG-GERAIIAHLE 298 Query: 307 QAYEALIGNKGTHI 320 +A EAL G GT + Sbjct: 299 KAVEALEGKTGTQV 312
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 506 bits (1305), Expect = 0.0 Identities = 193/409 (47%), Positives = 275/409 (67%), Gaps = 8/409 (1%) Query: 5 PIKVNSEIGALKTVLLKRPGKELENLVPDYLDGLLFDDIPYLEVAQKEHDHFAQVLREEG 64 PI + SEIG LK VLL RPG+ELENL P + LFDDIPYLEVA++EH+ FA +L+ Sbjct: 7 PINIFSEIGRLKKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQEHEVFASILKNNL 66 Query: 65 VEVLYLEKLAAESIENPQ-VRSEFIDDVLAESKKTILGHEEEIKTLFATLSNQELVDKIM 123 VE+ Y+E L +E + + + ++FI + E++ +K F++L+ ++ K++ Sbjct: 67 VEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINLLKDYFSSLTIDNMISKMI 126 Query: 124 SGVRKEEINPKCTHLVEYMDDKYPFYLDPMPNLYFTRDPQASIGHGITINRMFWRARRRE 183 SGV EE+ + L + ++ F +DPMPN+ FTRDP ASIG+G+TIN+MF + R+RE Sbjct: 127 SGVVTEELKNYTSSLDDLVNGANLFIIDPMPNVLFTRDPFASIGNGVTINKMFTKVRQRE 186 Query: 184 SIFIQYIVKHHPRFKDANIPIWLDRDCPFNIEGGDELVLSKDVLAIGVSERTSAQAIEKL 243 +IF +YI K+HP +K N+PIWL+R ++EGGDELVL+K +L IG+SERT A+++EKL Sbjct: 187 TIFAEYIFKYHPVYK-ENVPIWLNRWEEASLEGGDELVLNKGLLVIGISERTEAKSVEKL 245 Query: 244 ARRIFENPQATFKKVVAIEIPTSRTFMHLDTVFTMIDYDKFTMHSAILKAEGNMNIFIIE 303 A +F+N + +F ++A +IP +R++MHLDTVFT IDY FT ++ + +I+++ Sbjct: 246 AISLFKN-KTSFDTILAFQIPKNRSYMHLDTVFTQIDYSVFTSFTSD---DMYFSIYVLT 301 Query: 304 YDDVNKDIAIK-QSSHLKDTLEDVLGIDDIQFIPTGNGDVIDGAREQWNDGSNTLCIRPG 362 Y+ + I IK + + +KD L LG I I GD+I GAREQWNDG+N L I PG Sbjct: 302 YNPSSSKIHIKKEKARIKDVLSFYLG-RKIDIIKCAGGDLIHGAREQWNDGANVLAIAPG 360 Query: 363 VVVTYDRNYVSNDLLRQKGIKVIEISGSELVRGRGGPRCMSQPLFREDI 411 ++ Y RN+V+N L + GIKV I SEL RGRGGPRCMS PL REDI Sbjct: 361 EIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGPRCMSMPLIREDI 409
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 82.2 bits (203), Expect = 7e-23 Identities = 38/147 (25%), Positives = 78/147 (53%), Gaps = 2/147 (1%) Query: 1 MKKSKRLEIVSTIVKKHKIYKKEQIISYIEEYFGVRYSATTIAKDLKELNIYRVPIDCET 60 M K +R + I+ ++I +++++ +++ G + T+++D+KEL++ +VP + + Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKD-GYNVTQATVSRDIKELHLVKVPTNNGS 59 Query: 61 WIYKAINNQTEQEMREKFRHYCEHEVLSSIINGSYIIVKTSPGFAQGINYFIDQLNIEEI 120 + Y ++ K + + I++KT PG AQ I +D L+ EEI Sbjct: 60 YKY-SLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEEI 118 Query: 121 LGTVSGNDTTLILTASNDMAEYVYAKL 147 +GT+ G+DT LI+ ++D + V K+ Sbjct: 119 MGTICGDDTILIICRTHDDTKVVQKKI 145
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 440 bits (1133), Expect = e-152 Identities = 173/480 (36%), Positives = 249/480 (51%), Gaps = 42/480 (8%) Query: 64 NIYQDYAVTDVKTDKKGFTHYTLQPSVDGVHAPDKEVKVHADKSGKVVLING----DTDA 119 + ++ K D+ G T + ++ + H + G++ ++G + D Sbjct: 71 QARERLSLIGNKLDELGHTVMRFEQAIAASLCMGAVLVAHVN-DGELSSLSGTLIPNLDK 129 Query: 120 KKVKPTNKVTLSKDDAADKAFKAVKIDKHKAKNLKDKVIKENKVEIDGDSNKYVYNVELI 179 + +K +++ + + K A ++ K + ++ + D ++ + Y V + Sbjct: 130 RTLKTEAAISIQQAEMIAKQDVADRVTKERPAA-EEGKPTRLVIYPDEETPRLAYEVNVR 188 Query: 180 TVTPEISHWKVKIDAQTGEILEKMNLVKEA-----------AETGKGKGVLGDTKDINI- 227 +TP +W IDA G++L K N + EA + G G+GVLGD K IN Sbjct: 189 FLTPVPGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAGTSTVGVGRGVLGDQKYINTT 248 Query: 228 -NSIDGGFSLEDLTHQGKLSAFSFNDQTG-QATLITNEDENFVKDEQRAGVDANYYAKQT 285 +S G + L+D T + + ++T +L + D F A VDA+YYA Sbjct: 249 YSSYYGYYYLQDNTRGSGIFTYDGRNRTVLPGSLWADGDNQFFASYDAAAVDAHYYAGVV 308 Query: 286 YDYYKDTFGRESYDNQGSPIVSLTHVNNYGGQDNRNNAAWIGDKMIYGDGDGRTFTSLSG 345 YDYYK+ GR SYD + I S H YG NNA W G +M+YGDGDG+TF SG Sbjct: 309 YDYYKNVHGRLSYDGSNAAIRSTVH---YG--RGYNNAFWNGSQMVYGDGDGQTFLPFSG 363 Query: 346 ANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVD-----DEDFLMGEDVYTP 400 DVV HELTH VT TA L Y+++SGA+NE+ SD+FG V+ + D+ +GED+YTP Sbjct: 364 GIDVVGHELTHAVTDYTAGLVYQNESGAINEAMSDIFGTLVEFYANRNPDWEIGEDIYTP 423 Query: 401 GKEGDALRSMSNPEQFGQPAHMKDYVFTEKDNGGVHTNSGIPNKAAYNVIQ--------- 451 G GDALRSMS+P ++G P H +DNGGVHTNSGI NKAAY + Q Sbjct: 424 GVAGDALRSMSDPAKYGDPDHYSKRYTGTQDNGGVHTNSGIINKAAYLLSQGGVHYGVSV 483 Query: 452 -AIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAE--QVYEAWNEVGV 508 IG+ K +I+YRAL YLT SNF + A QAA DLY + E V +A+N VGV Sbjct: 484 TGIGRDKMGKIFYRALVYYLTPTSNFSQLRAACVQAAADLYGSTSQEVNSVKQAFNAVGV 543
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 39.1 bits (91), Expect = 6e-05 Identities = 37/172 (21%), Positives = 67/172 (38%), Gaps = 28/172 (16%) Query: 817 NKHKSLESVLTTRQVFLGKAGFFIMLGML-----QALIVSVGDLLILKAGVESP---VLF 868 ++ E++L T Q+ LG I+LG + +A + G ++ A + +L+ Sbjct: 95 EGQRTWEAMLYT-QLRLGD----IVLGEMAWAATKAALAGAGIGVVAAALGYTQWLSLLY 149 Query: 869 VLITI-FCSIIFNSIVYTCVSLLGNPGKAIAIVLLVLQIAG----GGGTFPIQTTPQFFQ 923 L I + F S+ +L P I L I G FP+ P FQ Sbjct: 150 ALPVIALTGLAFASLGMVVTAL--APSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQ 207 Query: 924 NISPYLPFTYAIDSLRETV-----GGIVPEILITKLIILTLFGIGFFVVGLI 970 + +LP +++ID +R + + + + I+ F F L+ Sbjct: 208 TAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPF---FLSTALL 256
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 63.6 bits (154), Expect = 5e-13 Identities = 50/176 (28%), Positives = 84/176 (47%), Gaps = 19/176 (10%) Query: 304 SNNDDSGQFNVVDSKDTRQFVKSIAKDAHRIGQDNDIYASVMIAQAILESDSGRSALAKS 363 N DDS D++ F+ ++ A Q + + +++AQA LES G+ + + Sbjct: 139 RNYDDSLPG------DSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRE 192 Query: 364 ---PNHNLFGIK--GAFEGNSVPFNTLEADGNKLYSINAGFRKYPSTKESLKDYSDLIKN 418 P++NLFG+K G ++G T E + + + A FR Y S E+L DY L+ Sbjct: 193 NGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTR 252 Query: 419 GIDGNRTIYKPTWKSEADSYKDATSHLSKTYATDPNYAKKLNSIIKHYQLTQFDDE 474 + + A + +DA YATDP+YA+KL ++I+ Q+ D+ Sbjct: 253 NPRYAAVTTAASAEQGAQALQDA------GYATDPHYARKLTNMIQ--QMKSISDK 300
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 77.0 bits (189), Expect = 3e-19 Identities = 41/183 (22%), Positives = 77/183 (42%), Gaps = 10/183 (5%) Query: 3 RKTALLVLDMQE----GIASSVPRIKNIIKANQRAIEAARQHRIPVIFIRLVLDKHFNDV 58 + LL+ DMQ + + + ++ Q IPV++ ++ +D Sbjct: 29 NRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDR 88 Query: 59 SSSNKVFSTIKAQGYAITEADASTRILEDLAPLEDEPIISKRRFSAFTGSYLEVYLRAND 118 + + G + +I+ +LAP +D+ +++K R+SAF + L +R Sbjct: 89 ALLTDFW------GPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEG 142 Query: 119 INHLVLTGVSTSGAVLSTALESVDKDYYITVLEDAVGDRSDDKHDFIIEQILSRSCDIES 178 + L++TG+ L TA E+ +D + DAV D S +KH +E R Sbjct: 143 RDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMALEYAAGRCAFTVM 202 Query: 179 VES 181 +S Sbjct: 203 TDS 205
>ENTEROTOXINA#Heat-labile enterotoxin A chain signature. Length = 258 Score = 28.4 bits (63), Expect = 0.005 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Query: 30 IELFEHTFGLQKELVKYVGIAEATTAALYSASFINKNISRLASLSTIGILSVAA 83 I L++H G Q V+Y +T+ +L SA ++I L+ ST I +A Sbjct: 57 INLYDHARGTQTGFVRYDDGYVSTSLSLRSAHLAGQSI--LSGYSTYYIYVIAT 108
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 27.4 bits (61), Expect = 0.043 Identities = 9/32 (28%), Positives = 14/32 (43%) Query: 23 IPRPIAFVTTLNQDASVNAAPFSFFNIVNNHP 54 IP T + + AP+ +NI N+ P Sbjct: 234 IPHADTQWTVETGTPAASIAPYRVYNIGNSSP 265
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 45.3 bits (107), Expect = 1e-08 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 5/101 (4%) Query: 48 EKNDEVIGYIN--GPVIKERYISDDLFKNVSINNSEGGYISVLGLVVAPNYQGQGIAGRL 105 E +D + Y+ G Y+ ++ + I ++ GY + + VA +Y+ +G+ L Sbjct: 51 EDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTAL 110 Query: 106 LNYFETLAKNHHRHGVTLTCRE---SLISFYEKYGYRNEGV 143 L+ AK +H G+ L ++ S FY K+ + V Sbjct: 111 LHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAV 151
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.7 bits (165), Expect = 2e-16 Identities = 16/48 (33%), Positives = 31/48 (64%) Query: 2 KDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYE 49 + I+D A+ LFS++G T+L +IAK+ + + ++Y+HF K ++ Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60