PredictBias

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score =  142 bits (361), Expect = 7e-40

		 Identities = 83/387 (21%), Positives = 149/387 (38%), Gaps = 84/387 (21%)

		

		Query: 5   IGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGET------LVGQPAKRQA 58

		           + IDLGT N+ + +       + E        PS++A  QD          VG  AK+  

		Sbjct: 13  LSIDLGTANTLIYVKGQGIV-LNE--------PSVVAIRQDRAGSPKSVAAVGHDAKQML 63

		

		Query: 59  VTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAE 118

		              P N + AI+ +           +D  I  F +                     +   

		Sbjct: 64  GRTPGN-IAAIRPM-----------KDGVIADFFVTEK------------------MLQH 93

		

		Query: 119 VLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALA 178

		            +K++     +    P    ++ VP      +R+A +++ + AG     +I EP AAA+ 

		Sbjct: 94  FIKQVHS---NSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIG 150

		

		Query: 179 YGL--DKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRL 236

		            GL   + TG+    V D+GGGT ++++I ++ V           +    +GG+ FD  +

		Sbjct: 151 AGLPVSEATGS---MVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEAI 198

		

		Query: 237 INYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA----QQTDVNLPYITADATG 292

		           INY+   +    G             +  AE+ K E+ SA    +  ++ +         

		Sbjct: 199 INYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGV 245

		

		Query: 293 PKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQD-AGLSVSDIDD--VILVGGQTRMPMV 349

		           P+   +  +   LE+L E  +   +  + VAL+       SDI +  ++L GG   +  +

		Sbjct: 246 PRGFTLN-SNEILEALQEP-LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNL 303

		

		Query: 350 QKKVAEFFGKEPRKDVNPDEAVAIGAA 376

		            + + E  G       +P   VA G  

		Sbjct: 304 DRLLMEETGIPVVVAEDPLTCVARGGG 330

		

		

		>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature.

		          Length = 52

		

		 Score = 61.4 bits (149), Expect = 4e-17

		 Identities = 18/46 (39%), Positives = 30/46 (65%)

		

		Query: 23 HKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYES 68

		            +++  ++++C+T ++   +TRK LCE+  R G  EVA F AYES

		Sbjct: 5  RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50

		

		

		>PF00577#Outer membrane usher protein FimD

		          Length = 878

		

		 Score =  176 bits (447), Expect = 2e-52

		 Identities = 59/257 (22%), Positives = 105/257 (40%), Gaps = 4/257 (1%)

		

		Query: 2   AASPDIAKTRHQINLSNSTSFSKDGYSSNNTGITGIAGEHDQLNYGI---YVNQQQQNND 58

		               D        + S S S   +G  +N  G+ G   E + L+Y +   Y      N+ 

		Sbjct: 605 WLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSG 664

		

		Query: 59  TSLGTNLSWRTPIAIIDGSYSHSKNAWQSGGSISSGLVVWPGGINITNQLSDTFAILDAP 118

		           ++    L++R      +  YSHS +  Q    +S G++    G+ +   L+DT  ++ AP

		Sbjct: 665 STGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAP 724

		

		Query: 119 GLEGAHINGQKYNRTNSKGQVVYDLIIPHRENHLVLDIANSESETELQGNRQIIAPYRGA 178

		           G + A +  Q   RT+ +G  V      +REN + LD        +L      + P RGA

		Sbjct: 725 GAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGA 784

		

		Query: 179 VSYVQFTTDQRKPWYIQALRPDGSPLTFGYDVLDLQENNIGVVGQGSRLFIRVDEIPTGI 238

		           +   +F         +  L  +  PL FG  V      + G+V    ++++    +   +

		Sbjct: 785 IVRAEFKARVGIKLLMT-LTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKV 843

		

		Query: 239 KVALNDEQNLFCTITFQ 255

		           +V   +E+N  C   +Q

		Sbjct: 844 QVKWGEEENAHCVANYQ 860

		

		

		>PF00577#Outer membrane usher protein FimD

		          Length = 878

		

		 Score = 91.1 bits (226), Expect = 9e-25

		 Identities = 27/128 (21%), Positives = 52/128 (40%), Gaps = 14/128 (10%)

		

		Query: 1   MAAWRYASQDYRTFSDHLYENDKHYHQSDYDDFYDIG------------RKNSLSANIMQ 48

		           +  +RY++  Y  F+D  Y     Y+    D    +             ++  L   + Q

		Sbjct: 476 LVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQ 535

		

		Query: 49  PLSNNLGNVSLSALWRNYWGRSGNAKDYQFSYSNNWQHISYTFSASQSYDENNKEEER-F 107

		            L      + LS   + YWG S   + +Q   +  ++ I++T S S + +   K  ++  

		Sbjct: 536 QL-GRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQML 594

		

		Query: 108 NLFISIPF 115

		            L ++IPF

		Sbjct: 595 ALNVNIPF 602

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score = 29.4 bits (66), Expect = 0.041

		 Identities = 19/103 (18%), Positives = 39/103 (37%), Gaps = 18/103 (17%)

		

		Query: 300 ILIADKQSVGERAVKGICGQVDGSVV------PGFIGLEAGQS-AFGDIYAWFGRVLGWP 352

		           + I++K+ +    +  +   ++G +        G I +   +      +    G     P

		Sbjct: 281 VRISEKEKIK---ITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSV---LGDTKLLP 334

		

		Query: 353 L-EQLAAQHPELKAQINASQKQ----LLPALTEAWAKNPSLDH 390

		             E++    P L+  +  S+ Q    LL AL E    +P L +

		Sbjct: 335 QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRY 377

		

		

		>BCTERIALGSPF#Bacterial general secretion pathway protein F

		           signature.

		          Length = 408

		

		 Score =  227 bits (581), Expect = 5e-73

		 Identities = 94/405 (23%), Positives = 182/405 (44%), Gaps = 13/405 (3%)

		

		Query: 6   LWRWHGITGDGNAQDGMLWAESRALLLMALQQQMVTPLSLKRIAINSAQ----------- 54

		            + +  +   G    G   A+S       L+++ + PLS+     +  +           

		Sbjct: 3   QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62

		

		Query: 55  WRGDKS--AEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAHDLEQGIAFSN 112

		            R   S  A +  QLATL+ A + L E L  +A+Q        L+ ++   + +G + ++

		Sbjct: 63  IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122

		

		Query: 113 ALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVKSALRYPIIILAM 172

		           A+  +   F  LY AM+  GE +G LD     LA   + ++Q+  +++ A+ YP ++  +

		Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182

		

		Query: 173 AIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLADFSGEWSWLLVLFGFLLAIANK 232

		           AI VV  +L  V+P+    +      LP  T+ +M ++D    +   ++L      +A +

		Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242

		

		Query: 233 LLMRRPTWLIVRQKLLLRIPIMGSLMRGQKLTQIFTILALTQSAGITFLQGVESVRETMR 292

		           +++R+    +   + LL +P++G + RG    +    L++  ++ +  LQ +    + M 

		Sbjct: 243 VMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMS 302

		

		Query: 293 CPYWVQLLTQIQHDISNGHPIWLALKNTGEFSPLCLQLVRTGEASGSLDLMLDNLAHHHR 352

		             Y    L+     +  G  +  AL+ T  F P+   ++ +GE SG LD ML+  A +  

		Sbjct: 303 NDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQD 362

		

		Query: 353 DNTMALADNLAALLEPTLLIITGGIIGTLVVAMYLPIFHLGDAMS 397

		               +       L EP L++    ++  +V+A+  PI  L   MS

		Sbjct: 363 REFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407

		

		

		>BCTERIALGSPG#Bacterial general secretion pathway protein G

		          signature.

		          Length = 145

		

		 Score = 49.1 bits (117), Expect = 2e-10

		 Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 1/79 (1%)

		

		Query: 1  MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQTFVPYRTAVELCALEH 60

		           DKQRGFTL+E+MVVI II +L+++ +P       KA     +   V    A+++  L++

		Sbjct: 4  TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDN 63

		

		Query: 61 GGLDTCD-GGSNGIPSPTT 78

		              T + G  + + +PT 

		Sbjct: 64 HHYPTTNQGLESLVEAPTL 82

		

		

		>BINARYTOXINB#Binary toxin B family signature.

		          Length = 764

		

		 Score = 34.3 bits (78), Expect = 4e-04

		 Identities = 12/55 (21%), Positives = 28/55 (50%), Gaps = 4/55 (7%)

		

		Query: 186 NDYYRKVKELRAKNQITLPVILKNERQINVFLRT----EDIDLINVINEETLLQQ 236

		            +   ++ EL A N  T+   +K   ++N+ +R      D + I V  +E+++++

		Sbjct: 589 QNIKNQLAELNATNIYTVLDKIKLNAKMNILIRDKRFHYDRNNIAVGADESVVKE 643

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 30.6 bits (69), Expect = 0.016

		 Identities = 14/95 (14%), Positives = 30/95 (31%), Gaps = 9/95 (9%)

		

		Query: 18  RPAMPRFKVSAFWLLILAWIFL-LVWIWWKGPMWTLYEEQWLKPLANRWLATAAWG---- 72

		           +  +          ++ A + + +VW      +W L      KP+A       +      

		Sbjct: 66  QGWLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVV 125

		

		Query: 73  IIALVW----LTVRVMKRLQQLEKMQKQQREEAVD 103

		           ++  +W          K  +Q E  Q +    A +

		Sbjct: 126 VVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQE 160

		

		

		>ENTSNTHTASED#Enterobactin synthetase component D signature.

		          Length = 234

		

		 Score = 26.5 bits (58), Expect = 0.013

		 Identities = 6/23 (26%), Positives = 10/23 (43%)

		

		Query: 45  AVYKDHPLQGSWKGYRDAHVEPD 67

		           +VYK    + +  G+  A V   

		Sbjct: 153 SVYKAFSDRVTLPGFNSAKVTSL 175

		

		

		>CARBMTKINASE#Bacterial carbamate kinase signature.

		          Length = 314

		

		 Score =  435 bits (1120), Expect = e-157

		 Identities = 141/315 (44%), Positives = 203/315 (64%), Gaps = 3/315 (0%)

		

		Query: 1   MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADMVLEMLASDYDIVLTHGNGPQVGLD 60

		           M + VV+A+GGN++ +     S E   + V+  A  + E++A  Y++V+THGNGPQVG  

		Sbjct: 1   MGKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSL 60

		

		Query: 61  LRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLARHG-EKKAVTVVTQVEVD 119

		           L   +      G+P  P+    A +QG IGY+IQQAL N L + G EKK VT++TQ  VD

		Sbjct: 61  LLHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVD 120

		

		Query: 120 KNDPGFAHPTKPIGAFFSESQRDKLQKANPDWCFVEDAGRGYRRVVASPEPKRIVEAPAI 179

		           KNDP F +PTKP+G F+ E    +L +    W   ED+GRG+RRVV SP+PK  VEA  I

		Sbjct: 121 KNDPAFQNPTKPVGPFYDEETAKRLAREK-GWIVKEDSGRGWRRVVPSPDPKGHVEAETI 179

		

		Query: 180 KALIQQGFVVIGAGGGGIPVVRTEAGDYQSVDAVIDKDLSTALLAREIHADILVITTDVE 239

		           K L+++G +VI +GGGG+PV+  E G+ + V+AVIDKDL+   LA E++ADI +I TDV 

		Sbjct: 180 KKLVERGVIVIASGGGGVPVIL-EDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVN 238

		

		Query: 240 KVCIHFGKPQQQALDRVDIATMTRYMQEGHFSPGSMLPKIIASLTFLEQGGKEVIITTPE 299

		              +++G  ++Q L  V +  + +Y +EGHF  GSM PK++A++ F+E GG+  II   E

		Sbjct: 239 GAALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLE 298

		

		Query: 300 CLPAALRGETGTHII 314

		               AL G+TGT ++

		Sbjct: 299 KAVEALEGKTGTQVL 313

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 57.6 bits (139), Expect = 4e-11

		 Identities = 48/195 (24%), Positives = 82/195 (42%), Gaps = 4/195 (2%)

		

		Query: 1   MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQAFALDKMQMGWIFSAGI 60

		           M+T    S+     + I LC L      L+     ++   IA  F        W+ +A +

		Sbjct: 1   MNTSYSQSNLRHNQILIWLCILS-FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFM 59

		

		Query: 61  LGLLPGALVGGMLADRYGRKRILIGSVALFGLFSLATAIAWD-FPSLVFARLMTGVGLGA 119

		           L    G  V G L+D+ G KR+L+  + +    S+   +    F  L+ AR + G G  A

		Sbjct: 60  LTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG-AA 118

		

		Query: 120 ALPNLIA-LTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGFAGANLAWQTVFWVGGVVP 178

		           A P L+  + +       RG A  L+   V +G  +   +G   A+    +   +  ++ 

		Sbjct: 119 AFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMIT 178

		

		Query: 179 LILVPLLMRWLPESA 193

		           +I VP LM+ L +  

		Sbjct: 179 IITVPFLMKLLKKEV 193

		

		

		>TRNSINTIMINR#Translocated intimin receptor (Tir) signature.

		          Length = 549

		

		 Score = 28.2 bits (62), Expect = 0.018

		 Identities = 14/56 (25%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

		

		Query: 11  LKAGLVTSKKAAKVERTAKKSRVQAREARAAVEENKKAQLERDKQLSEQQKQAALA 66

		           + +G +      ++ + AK++   AR+   AVE N +AQ   + Q + +Q++  L+

		Sbjct: 308 IPSGELKDDIVEQIAQQAKEAGEVARQQ--AVESNAQAQQRYEDQHARRQEELQLS 361

		

		

		>FLGPRINGFLGI#Flagellar P-ring protein signature.

		          Length = 373

		

		 Score = 28.7 bits (64), Expect = 0.015

		 Identities = 13/31 (41%), Positives = 20/31 (64%)

		

		Query: 12  QVIIDETAGEVVIGANTRICHGAVIQGPVVI 42

		           +V+I+E  G +VIGA+ RI   AV  G + +

		Sbjct: 262 KVVINERTGTIVIGADVRISRVAVSYGTLTV 292

		

		

		>BINARYTOXINB#Binary toxin B family signature.

		          Length = 764

		

		 Score = 29.7 bits (66), Expect = 0.019

		 Identities = 19/69 (27%), Positives = 30/69 (43%)

		

		Query: 265 DIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYF 324

		           +   EL +  +L +   QV G  A   F      +D      E L  I+   A +IF+  

		Sbjct: 466 NQFLELEKTKQLRLDTDQVYGNIATYNFENGRVRVDTGSNWSEVLPQIQETTARIIFNGK 525

		

		Query: 325 ALDLAEKKI 333

		            L+L E++I

		Sbjct: 526 DLNLVERRI 534

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 39.4 bits (92), Expect = 3e-05

		 Identities = 71/347 (20%), Positives = 135/347 (38%), Gaps = 20/347 (5%)

		

		Query: 62  KFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLEPGTQLRWMAALAVVIAFCS 121

		           +F  +P++   +  F   RR  LL +     V  A M          W+  +  ++A  +

		Sbjct: 56  QFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAIMAT----APFLWVLYIGRIVAGIT 109

		

		Query: 122 ASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSGGLALWLADKWLGWQGMYWLMA 181

		            +   V  A+  D+   +ER          +  GM+    L   +          ++  A

		Sbjct: 110 GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG--FSPHAPFFAAA 167

		

		Query: 182 AL-LIPCIIATLLAPEP--TDTIPVPKTLEQAVVAPLRDFFGRNNAWLILLLIVLYKLGD 238

		           AL  +  +    L PE    +  P+ +     + +          A L+ +  ++  +G 

		Sbjct: 168 ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQ 227

		

		Query: 239 AFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYGGILMQRLSLFRALLIFGIL 298

		             A +L   F      +DA  +G+     G+L ++  A+  G +  RL   RAL+  G++

		Sbjct: 228 VPA-ALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALM-LGMI 285

		

		Query: 299 QGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGTSAFVALLMTLCNKSFSATQFALLS 358

		             A   GY LL+   +   +    V      GG+G  A  A+L    ++         L+

		Sbjct: 286 --ADGTGYILLAFATRGWMAFPIMVLL--ASGGIGMPALQAMLSRQVDEERQGQLQGSLA 341

		

		Query: 359 ALSAVGRVYVGPVAGWFVEAHGWSTF--YLFSVAAAVPGLILLLVCR 403

		           AL+++  + VGP+    + A   +T+  + +   AA+  L L  + R

		Sbjct: 342 ALTSLTSI-VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387

		

		

		>PF06291#Lambda prophage Bor protein

		          Length = 102

		

		 Score = 26.5 bits (58), Expect = 0.027

		 Identities = 11/34 (32%), Positives = 18/34 (52%)

		

		Query: 3  KKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQ 36

		          KK+LF      ++ GCA+   T+   PT   P++

		Sbjct: 7  KKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKE 40

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 29.0 bits (65), Expect = 0.043

		 Identities = 16/73 (21%), Positives = 29/73 (39%), Gaps = 13/73 (17%)

		

		Query: 60  ERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIG 119

		           E    P+  E  +     ++G+  A +     +Y    RL   D           +++ G

		Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQ----EIYRVLARLMQTD---------LTLMITG 167

		

		Query: 120 PTGSGKTLLAETL 132

		            +G+GK L+A  L

		Sbjct: 168 ESGTGKELVARAL 180

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 34.3 bits (78), Expect = 0.002

		 Identities = 34/133 (25%), Positives = 68/133 (51%), Gaps = 15/133 (11%)

		

		Query: 191 ERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDDAPD- 249

		             LE   A +E +  +L      R  +++ ++ S+      +Q++A  ++L E +   + 

		Sbjct: 291 AALEAEKADLEHQSQVLNAN---RQSLRRDLDASREAK---KQLEAEHQKLEEQNKISEA 344

		

		Query: 250 ENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMS-AEATVVRGYIDWMVQVPWNARSK 308

		             ++L+R +DA++   EAK++ EAE QKL+  + +S A    +R  +D   +    A+ +

		Sbjct: 345 SRQSLRRDLDASR---EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASRE----AKKQ 397

		

		Query: 309 VKKDLRQAQEILD 321

		           V+K L +A   L 

		Sbjct: 398 VEKALEEANSKLA 410

		

		

		>DNABINDINGHU#Prokaryotic integration host factor signature.

		          Length = 91

		

		 Score =  117 bits (294), Expect = 3e-38

		 Identities = 49/88 (55%), Positives = 67/88 (76%)

		

		Query: 2  NKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGR 61

		          NK  LI K+A   +++K  +  A+DA+ ++V+  L +G+ V L+GFG F V+ERAAR GR

		Sbjct: 3  NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62

		

		Query: 62 NPQTGKEITIAAAKVPSFRAGKALKDAV 89

		          NPQTG+EI I A+KVP+F+AGKALKDAV

		Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90

		

		

		>BCTERIALGSPF#Bacterial general secretion pathway protein F

		           signature.

		          Length = 408

		

		 Score = 31.0 bits (70), Expect = 0.007

		 Identities = 33/141 (23%), Positives = 56/141 (39%), Gaps = 25/141 (17%)

		

		Query: 247 IWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEA 306

		            W+ L L+ G +A   +LR          R+          + + P++    G+I     

		Sbjct: 228 PWMLLALLAGFMAFRVMLR------QEKRRVS-----FHRRLLHLPLI----GRIARGLN 272

		

		Query: 307 LARWPQTDGSWLSPDSFIPLAQQTGLS-EPLTLLIIRSAFEDMGDWLRQHPQQHISINLE 365

		            AR+ +T     +  S +PL Q   +S + ++    R       D +R+    H +  LE

		Sbjct: 273 TARYARTLSILNA--SAVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVSLHKA--LE 328

		

		Query: 366 STVLTSEKIPQLLREMINQSG 386

		            T L     P ++R MI  SG

		Sbjct: 329 QTAL----FPPMMRHMI-ASG 344

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 1367 bits (3541), Expect = 0.0

		 Identities = 801/1033 (77%), Positives = 915/1033 (88%), Gaps = 1/1033 (0%)

		

		Query: 1    MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60

		            M NFFI RPIFAWV+AII+M+AG LAIL+LPVAQYPTIAPPAV++SA+YPGADA+TVQDT

		Sbjct: 1    MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60

		

		Query: 61   VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120

		            VTQVIEQNMNGIDNLMYMSS SDS G+V ITLTF+SGTD DIAQVQVQNKLQLA PLLPQ

		Sbjct: 61   VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120

		

		Query: 121  EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180

		            EVQQQG+SVEKSSSS+LMV G ++ +   TQ+DISDYVA+N+KD +SR +GVGDVQLFG+

		Sbjct: 121  EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180

		

		Query: 181  QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240

		            QYAMRIW++ + LNK++LTPVDVI  +K QN Q+AAGQLGGTP + GQQLNASIIAQTR 

		Sbjct: 181  QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240

		

		Query: 241  TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300

		             + EEFGK+ L+VN DGS V L+DVA++ELGGENY++IA  NG+PA+GLGIKLATGANAL

		Sbjct: 241  KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300

		

		Query: 301  DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360

		            DTA AI+A+LA+++PFFP G+K++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ

		Sbjct: 301  DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360

		

		Query: 361  NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420

		            N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM

		Sbjct: 361  NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420

		

		Query: 421  AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480

		             E+ LPPKEAT KSM QIQGALVGIAMVLSAVF+PMAFFGGSTGAIYRQFSITIVSAMAL

		Sbjct: 421  MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480

		

		Query: 481  SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540

		            SVLVALILTPALCAT+LKP++   H E K GFFGWFN  F+ S +HYT+SVG IL STGR

		Sbjct: 481  SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539

		

		Query: 541  YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600

		            YL++Y +IV GM  LF+RLPSSFLP+EDQGVF+TM+QLPAGATQERTQKVL++VT YYL 

		Sbjct: 540  YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599

		

		Query: 601  KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660

		             EK NVESVF VNGF F+G+ QN G+AFVSLK W +R G+EN  EA+  RA     +I+D

		Sbjct: 600  NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659

		

		Query: 661  AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720

		              V  FN+PAIVELGTATGFDFELIDQAGLGH+ LTQARNQLL  AA+HP  L SVRPNG

		Sbjct: 660  GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719

		

		Query: 721  LEDTPQFKIDIDQEKAQALGVSINDINTSLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780

		            LEDT QFK+++DQEKAQALGVS++DIN ++  A GG+YVNDFIDRGRVKK+YV ++AK+R

		Sbjct: 720  LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779

		

		Query: 781  MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840

		            MLP+D+   YVR+A+G+MVPFSAF++S W YGSPRLERYNGLPSMEI G+AAPG S+G+A

		Sbjct: 780  MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839

		

		Query: 841  MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900

		            M LME LASKLP G+GYDWTGMSYQERLSGNQAP+L AIS +VVFLCLAALYESWSIP S

		Sbjct: 840  MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899

		

		Query: 901  VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960

		            VMLVVPLG++G LLAAT     NDVYF VGLLTTIGLSAKNAILIVEFAKDLM+KEGKG+

		Sbjct: 900  VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959

		

		Query: 961  IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF 1020

		            +EATL AVRMRLRPILMTSLAFILGV+PL IS GAGSGAQNAVG GVMGGMV+AT+LAIF

		Sbjct: 960  VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019

		

		Query: 1021 FVPVFFVVVRRRF 1033

		            FVPVFFVV+RR F

		Sbjct: 1020 FVPVFFVVIRRCF 1032

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 41.7 bits (98), Expect = 4e-06

		 Identities = 32/212 (15%), Positives = 71/212 (33%), Gaps = 23/212 (10%)

		

		Query: 100 TYQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTA 159

		             +  Y  A  +L      + + Q+           Q +++   ++ L   +Q    +  

		Sbjct: 256 EQENKYVEAVNELR--VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313

		

		Query: 160 AKAAVETARINLAYTKVTSPISGRIGKSNV-TEGALVQNGQATALATVQQLDPIYLDVTQ 218

		               +         + + +P+S ++ +  V TEG +V   + T +  V + D + +    

		Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALV 372

		

		Query: 219 SSNDFLRLKQELA----------NGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVD 268

		            + D   +                          KV  I  D I+  + G +    ++++

		Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLV---GKVKNINLDAIEDQRLGLVFNVIISIE 429

		

		Query: 269 QTTGSITLRAIFPNPDHTLLPGMFVRARLEEG 300

		           +   S   + I       L  GM V A ++ G

		Sbjct: 430 ENCLSTGNKNIP------LSSGMAVTAEIKTG 455

		

		

		

		 Score = 34.4 bits (79), Expect = 8e-04

		 Identities = 24/125 (19%), Positives = 43/125 (34%), Gaps = 13/125 (10%)

		

		Query: 49  PLQITTELPGR-TSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDS 107

		            ++I     G+ T + R  E++P  + I+ +   KEG  +  G  L ++     +A    

		Sbjct: 79  QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA---- 134

		

		Query: 108 AKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETA 167

		              D  K Q++   A+L   RYQ L         E ++                      

		Sbjct: 135 ---DTLKTQSSLLQARLEQTRYQILS-----RSIELNKLPELKLPDEPYFQNVSEEEVLR 186

		

		Query: 168 RINLA 172

		             +L 

		Sbjct: 187 LTSLI 191

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score =  222 bits (567), Expect = 5e-76

		 Identities = 215/215 (100%), Positives = 215/215 (100%)

		

		Query: 1   MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60

		           MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS

		Sbjct: 1   MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60

		

		Query: 61  EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120

		           EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV

		Sbjct: 61  EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120

		

		Query: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180

		           GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF

		Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180

		

		Query: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215

		           APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE

		Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 31.7 bits (72), Expect = 0.017

		 Identities = 19/125 (15%), Positives = 40/125 (32%), Gaps = 6/125 (4%)

		

		Query: 28  QNTAFARASSNGDLPTKADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRIKEE 87

		            N    RA     L      +        +  L     L+ +      A L++ ++  E 

		Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSR--LDDFSSLLHKQAIAKHAVLEQENKYVEA 264

		

		Query: 88  TVQLRQKVAEAPEKMRQATAALTALSDVDND--EETRKIL--STLSLRQLETRVAQALDD 143

		             +LR   ++  +   +  +A      V      E    L  +T ++  L   +A+  + 

		Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEER 324

		

		Query: 144 LQNAQ 148

		            Q + 

		Sbjct: 325 QQASV 329

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 42.4 bits (99), Expect = 6e-06

		 Identities = 42/249 (16%), Positives = 79/249 (31%), Gaps = 27/249 (10%)

		

		Query: 402  PLPETTSQVLAARQ--QLQCVQGATKAKKSESAAATRARPVNNAALERLASVTDRVQARP 459

		            P  E  +Q +          +Q    +  S +     AR  + A +   A  T       

		Sbjct: 983  PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEE--IARV-DEAPVPPPAPATPSETTET 1039

		

		Query: 460  VPSALEKASAKKEAYRWKATTPVMQQKE--------VVATPKALKKA---LEHEKTPELA 508

		            V    ++ S   E     AT    Q +E        V A  +  + A    E ++T    

		Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099

		

		Query: 509  AKLAA---------EAIERDPWAAQVSQLSLPKLVEQVALNAWKE-ESDNAVCLHLRSSQ 558

		             K  A            E+     +V+    PK  +   +    E   +N   ++++  Q

		Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159

		

		Query: 559  RHLNNRGAQQKLAEALS-MLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESII 617

		               N     ++ A+  S  ++    E T V   N  V  P     A  +  +     +  

		Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKP 1219

		

		Query: 618  ADNNIQTLR 626

		             + + +++R

		Sbjct: 1220 KNRHRRSVR 1228

		

		

		>BLACTAMASEA#Beta-lactamase class A signature.

		          Length = 286

		

		 Score = 27.8 bits (62), Expect = 0.046

		 Identities = 11/43 (25%), Positives = 18/43 (41%)

		

		Query: 38 GQLAAVAIVTCDGNVYSAGDSDYRFALESISKVCTLALALEDV 80

		          G++  + +    G   +A  +D RF + S  KV      L  V

		Sbjct: 38 GRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARV 80

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 77.8 bits (191), Expect = 5e-19

		 Identities = 49/212 (23%), Positives = 81/212 (38%), Gaps = 7/212 (3%)

		

		Query: 16  KSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNS----MGFT--GVLIDLDS 69

		           K   ITG + GIG   A  L  QG H+ A    P+ +E++ S              D+  

		Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68

		

		Query: 70  PESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRL 129

		             ++D     +       +  + N AG    G + ++S  + E  FS N  G    +  +

		Sbjct: 69  SAAIDEITARIEREMGP-IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127

		

		Query: 130 LPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEP 189

		              M+    G IV   S    +      AYA+SK A   ++  L +EL    I+ +++ P

		Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187

		

		Query: 190 GPIRTRFTDNVNQTQSDKPVENPGIAARFTLG 221

		           G   T    ++   ++       G    F  G

		Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTG 219

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 29.3 bits (65), Expect = 0.014

		 Identities = 12/20 (60%), Positives = 13/20 (65%)

		

		Query: 41  LVGESGSGKSTLLAILAGLD 60

		           L G  G GKSTL+  L GLD

		Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 31.0 bits (70), Expect = 0.011

		 Identities = 17/150 (11%), Positives = 44/150 (29%), Gaps = 8/150 (5%)

		

		Query: 299 RSQLNYSEENLKQARAALERLYTALRGTEKTVAPAGGEAFEARFIEAMDDDFNTP----- 353

		            +    ++ +L QAR    R     R  E    P      E  F    +++         

		Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192

		

		Query: 354 EAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEV 413

		           E +S   +   +      +  A    + + + +   +  + +   + F           +

		Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS---LLHKQAI 249

		

		Query: 414 AEIEALIQQRLDARKAKDWAAADAARDRLN 443

		           A+   L Q+        +     +  +++ 

		Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIE 279

		

		

		>CARBMTKINASE#Bacterial carbamate kinase signature.

		          Length = 314

		

		 Score =  387 bits (995), Expect = e-138

		 Identities = 126/310 (40%), Positives = 176/310 (56%), Gaps = 16/310 (5%)

		

		Query: 2   KTLVVALGGNALLQRGEALTAENQYRNIASAVPALARL-ARSYRLAIVHGNGPQVGLLAL 60

		           K +V+ALGGNAL QRG+  + E    N+      +A + AR Y + I HGNGPQVG L L

		Sbjct: 3   KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62

		

		Query: 61  QNLAWKE---VEPYPLDVLVAESQGMIGYMLAQSLSAQPQM----PPVTTVLTRIEVSPD 113

		              A +    +   P+DV  A SQG IGYM+ Q+L  + +       V T++T+  V  +

		Sbjct: 63  HMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKN 122

		

		Query: 114 DPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRD-GKYLRRVVASPQPRKILDSEAIELL 172

		           DPAF  P K +GP Y  E  + L    GW +K D G+  RRVV SP P+  +++E I+ L

		Sbjct: 123 DPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKL 182

		

		Query: 173 LKEGHVVICSGGGGVPVTEDG---AGSEAVIDKDLAAALLAEQINADGLVILTDADAVYE 229

		           ++ G +VI SGGGGVPV  +     G EAVIDKDLA   LAE++NAD  +ILTD +    

		Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242

		

		Query: 230 NWGTPQQRAIRHATPDELAPFAKAD----GSMGPKVTAVSGYVRSRGKPAWIGALSRIEE 285

		            +GT +++ +R    +EL  + +      GSMGPKV A   ++   G+ A I  L +  E

		Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVE 302

		

		Query: 286 TLAGEAGTCI 295

		            L G+ GT +

		Sbjct: 303 ALEGKTGTQV 312

		

		

		>PF07201#Hypersensitivity response secretion protein HrpJ

		          Length = 293

		

		 Score = 31.7 bits (72), Expect = 0.014

		 Identities = 17/72 (23%), Positives = 25/72 (34%), Gaps = 1/72 (1%)

		

		Query: 629 PAAVSDLRAALELEPNNSNIQAALGYALWDSGDIAQSREMLEQAHKRLPDDPALIRQLAY 688

		              VS+L + L     N ++     Y    S + ++  +ML      L   P L      

		Sbjct: 100 KQNVSELLSLL-SNSPNISLSQLKAYLEGKSEEPSEQFKMLCGLRDALKGRPELAHLSHL 158

		

		Query: 689 VNQRLDDMPATQ 700

		           V Q L  M   Q

		Sbjct: 159 VEQALVSMAEEQ 170

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 36.3 bits (84), Expect = 2e-04

		 Identities = 82/394 (20%), Positives = 145/394 (36%), Gaps = 38/394 (9%)

		

		Query: 27  FISIVSLGLLGVAVPVQIQMMTHSTWQV---GLSVTLTGGAMFVGLMVGGVLADRYERKK 83

		            +  V +GL+   +P  ++ + HS       G+ + L     F    V G L+DR+ R+ 

		Sbjct: 15  ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74

		

		Query: 84  VILLARGTCGIGFIGLCLNALL--PEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGR 141

		           V+L       +   G  ++  +    P L  +Y+  +  G   + G  A  A    +   

		Sbjct: 75  VLL-------VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA-GAYIADITDG 126

		

		Query: 142 ENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPP 201

		           +   +           G V  P++GGL+   GG + +    AA     L  L     LP 

		Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLM---GGFSPHAPFFAAAALNGLNFLTGCFLLPE 183

		

		Query: 202 PPQPREHPLK----SLLAGFRFLLASPLVGGIALLGGLLTMAS----AVRVLYPALADNW 253

		             +    PL+    + LA FR+     +V  +  +  ++ +      A+ V++    D +

		Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG--EDRF 241

		

		Query: 254 QMSAAQIGFLYAAIP-LGAAIGALTSGKLAHSARPGLLMLLSTLGS---FLAIGLFGLMP 309

		              A  IG   AA   L +   A+ +G +A        ++L  +     ++ +       

		Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301

		

		Query: 310 MWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGG 369

		           M    +V LA  G            ML  Q  E   G++ G   A       +G  L   

		Sbjct: 302 MAFPIMVLLASGGIGMPALQ----AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357

		

		Query: 370 LGAMMTPVASASASGFGLLIIGVLLLLVLVELRR 403

		           + A     +  + +G+  +    L LL L  LRR

		Sbjct: 358 IYA----ASITTWNGWAWIAGAALYLLCLPALRR 387

		

		

		>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature.

		          Length = 296

		

		 Score = 63.4 bits (154), Expect = 1e-13

		 Identities = 61/289 (21%), Positives = 105/289 (36%), Gaps = 35/289 (12%)

		

		Query: 40  HTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQ 99

		           H     P RIV+        LLA+               VAD   + R W     E  L 

		Sbjct: 29  HAAAIDPNRIVALEWLPVELLLALGIVPYG---------VADTINY-RLW---VSEPPLP 75

		

		Query: 100 RLYIG-----EPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKS--- 151

		              I      EP+ E +    P  ++ SA  G S     + L+ IAP    N+ D     

		Sbjct: 76  DSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPS----PEMLARIAPGRGFNFSDGKQPL 131

		

		Query: 152 --WQSLLTQLGEITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLW 209

		              +  LT++ ++   +  A   +AQ++  + + K +          +          ++

		Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVF 191

		

		Query: 210 TPESAQGQMLEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQ 269

		            P S   ++L++ G          NA Q +        +  + LAA  + + L     + 

		Sbjct: 192 GPNSLFQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNS 243

		

		Query: 270 KDADAIYANPLLAHLPAVQNKQVYTLGTETFRLDYYSAMQVLDRLNSLL 318

		           KD DA+ A PL   +P V+  +   +    F     SAM  +  L++ +

		Sbjct: 244 KDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAI 292

		

		

		>ISCHRISMTASE#Isochorismatase signature.

		          Length = 312

		

		 Score =  440 bits (1134), Expect = e-159

		 Identities = 147/299 (49%), Positives = 194/299 (64%), Gaps = 18/299 (6%)

		

		Query: 1   MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANI 60

		           MAIP +Q Y +P + D+PQNKV W  +P RA LLIHDMQ+YFV  +      + ++ ANI

		Sbjct: 1   MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60

		

		Query: 61  AALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTV 120

		             L++ C Q  IPV YTAQP  Q+ +DRALL D WGPGL   P ++K++  L P+ DD V

		Sbjct: 61  RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120

		

		Query: 121 LVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 180

		           L KWRYSAF R+ L +M+++ GR+QLIITG+YAHIGC+ TA +AFM DIK F V DA+AD

		Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180

		

		Query: 181 FSRDEHLMSLKYVAGRSGRVVMTEGLL------PAPVPARKA-----------ALREVIL 223

		           FS ++H M+L+Y AGR    VMT+ LL      PA V    A            +R+ I 

		Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240

		

		Query: 224 PLLDESDEPFDDD-NLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLS 281

		            LL E+ E   D  +L+D GLDSVR+M L  +WR+   ++ FV LA+ PTI+ W KLL+

		Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  360 bits (925), Expect = e-129

		 Identities = 110/258 (42%), Positives = 150/258 (58%), Gaps = 20/258 (7%)

		

		Query: 5   GKNVWVTGAGKGIGYATALAFVEAGAKVTGFD---------------QAFAQEQYPFATE 49

		           GK  ++TGA +GIG A A      GA +   D               +A   E +P    

		Sbjct: 8   GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP---- 63

		

		Query: 50  VMDVADAAQVAQVCQRLLAETERLDVLVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109

		             DV D+A + ++  R+  E   +D+LVN AG+LR G    LS E+W+ TF+VN  G FN

		Sbjct: 64  -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122

		

		Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAVSGVRC 169

		             +        +R G+IVTV S+ A  PR  M+AY +SKAA       +GLELA   +RC

		Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182

		

		Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229

		           N+VSPGST+TDMQ +LW  ++  EQ I+G  E FK GIPL K+A+P +IA+ +LFL S  

		Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242

		

		Query: 230 ASHITLQDIVVDGGSTLG 247

		           A HIT+ ++ VDGG+TLG

		Sbjct: 243 AGHITMHNLCVDGGATLG 260

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 94.5 bits (235), Expect = 1e-24

		 Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 1/125 (0%)

		

		Query: 2   TNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGI 61

		             +L+ +D+ AIR  L  AL   G  V             A    DL++ D+ +PD +  

		Sbjct: 4   ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63

		

		Query: 62  EFIRDLRQWSP-VPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS 120

		           + +  +++  P +PV+V+SA++     I A + GA DYL KPF + EL   +  AL    

		Sbjct: 64  DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123

		

		Query: 121 ATAAP 125

		              + 

		Sbjct: 124 RRPSK 128

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 31.4 bits (71), Expect = 0.014

		 Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 4/48 (8%)

		

		Query: 785 LLENAVKYAGAQAE----IGIDAHFEGENLQLDVWDNGPGLPPGQEQT 828

		           L+EN +K+  AQ      I +    +   + L+V + G       +++

		Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES 310

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 32.1 bits (73), Expect = 0.002

		 Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 12/82 (14%)

		

		Query: 55  RVARLRKNACLKYQATPEGLRYPASRGL----RAEQMRELLNGHYIIHR-----KNLLIT 105

		            +  +   A  + +  P  L   +  G+    R+  M+E+     ++ R       L+IT

		Sbjct: 110 ELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYR---VLARLMQTDLTLMIT 166

		

		Query: 106 GPTGCGKSWIANALGEQACRQK 127

		           G +G GK  +A AL +   R+ 

		Sbjct: 167 GESGTGKELVARALHDYGKRRN 188

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 56.6 bits (136), Expect = 1e-10

		 Identities = 30/188 (15%), Positives = 58/188 (30%), Gaps = 6/188 (3%)

		

		Query: 99   EQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEE 158

		            E E+  Q             QA+  +          E A    A          ++  E 

		Sbjct: 984  EVEKRNQTVDTTNITTPNNIQADVPSVP----SNNEEIARVDEAPVPPPAPATPSETTET 1039

		

		Query: 159  AAK--KAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAAAEKA 216

		             A+  K  +   +K E +A +  A+ ++ A+ A + +K   +  E A + +  K      

		Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099

		

		Query: 217  AADKKAAEKAAADKAAADKKAAAEKAAADKKAAAAKAAAEKAAADKKAAAAKAAAEKAAA 276

		              +    EK    K   +K     K  +       ++   +  A+           K   

		Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159

		

		Query: 277  AKAAAEAD 284

		            ++    AD

		Sbjct: 1160 SQTNTTAD 1167

		

		

		

		 Score = 52.4 bits (125), Expect = 2e-09

		 Identities = 33/217 (15%), Positives = 69/217 (31%), Gaps = 1/217 (0%)

		

		Query: 66   RMQSQESSAKRSDEQRKIKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAK 125

		            R  ++E+ +      +  +  Q+  E +E Q  E +    +EKE  A  E +K  E    

		Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125

		

		Query: 126  QAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKK 185

		             +++  KQ +    +  A+   + +      +E   +    A  +  A+   +  E    

		Sbjct: 1126 TSQVSPKQEQSETVQPQAEPARENDP-TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVT 1184

		

		Query: 186  AEAAAAALKKKAEAAEAAAAEARKKAAAEKAAADKKAAEKAAADKAAADKKAAAEKAAAD 245

		                        E  E       +     +++   K   + +      + + A   +   

		Sbjct: 1185 ESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDR 1244

		

		Query: 246  KKAAAAKAAAEKAAADKKAAAAKAAAEKAAAAKAAAE 282

		               A     +    A    A AKA        KA ++

		Sbjct: 1245 STVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQ 1281

		

		

		

		 Score = 51.6 bits (123), Expect = 4e-09

		 Identities = 25/195 (12%), Positives = 67/195 (34%), Gaps = 5/195 (2%)

		

		Query: 68   QSQESSAKRSDEQRKIKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQA 127

		            Q+   S   ++E+    ++           +E         ++ +   +K   E+ A + 

		Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN--EQDATET 1061

		

		Query: 128  ELKQKQ-AEEAAAKAAADAKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKKA 186

		              + ++ A+EA +   A+ +    A + +  +  +          E E  KA  E +K  

		Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE-EKAKVETEKTQ 1120

		

		Query: 187  EAAAAALKKKAEAAEAAAAEARKKAAAEKAAADKKAAEKAAADKAAADKKAAAEKAAADK 246

		            E      +   +  ++   + + + A E         E  +     AD +  A++ +++ 

		Sbjct: 1121 EVPKVTSQVSPKQEQSETVQPQAEPARENDPT-VNIKEPQSQTNTTADTEQPAKETSSNV 1179

		

		Query: 247  KAAAAKAAAEKAAAD 261

		            +    ++        

		Sbjct: 1180 EQPVTESTTVNTGNS 1194

		

		

		

		 Score = 51.2 bits (122), Expect = 5e-09

		 Identities = 28/193 (14%), Positives = 61/193 (31%), Gaps = 5/193 (2%)

		

		Query: 87   QAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAK 146

		            QA          E  R+ +      A     +  E  A+      KQ  +   K   DA 

		Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN----SKQESKTVEKNEQDAT 1059

		

		Query: 147  AKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAE 206

		                 + + A+EA     A+ +    A++     E Q   E    A  +K E A+    +

		Sbjct: 1060 ETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT-ETKETATVEKEEKAKVETEK 1118

		

		Query: 207  ARKKAAAEKAAADKKAAEKAAADKAAADKKAAAEKAAADKKAAAAKAAAEKAAADKKAAA 266

		             ++        + K+   +    +A   ++        + ++     A  +  A + ++ 

		Sbjct: 1119 TQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSN 1178

		

		Query: 267  AKAAAEKAAAAKA 279

		             +    ++     

		Sbjct: 1179 VEQPVTESTTVNT 1191

		

		

		

		 Score = 51.2 bits (122), Expect = 6e-09

		 Identities = 27/242 (11%), Positives = 81/242 (33%), Gaps = 23/242 (9%)

		

		Query: 51   DAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKIKEQQAAE-ELREKQAAEQER------L 103

		            D   V   A     +  ++   ++K+  +  +  EQ A E   + ++ A++ +       

		Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080

		

		Query: 104  KQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKA 163

		            +  E  +  ++ ++ Q     K+    +K+            KAK E +    +E  K  

		Sbjct: 1081 QTNEVAQSGSETKETQ-TTETKETATVEKE-----------EKAKVETEKT--QEVPKVT 1126

		

		Query: 164  AADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAE--ARKKAAAEKAAADKK 221

		            +  + K+ ++E  +  AE  ++ +      + +++    A  E  A++ ++  +    + 

		Sbjct: 1127 SQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTES 1186

		

		Query: 222  AAEKAAADKAAADKKAAAEKAAADKKAAAAKAAAEKAAADKKAAAAKAAAEKAAAAKAAA 281

		                         +            + ++     +     ++          ++   + 

		Sbjct: 1187 TTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRST 1246

		

		Query: 282  EA 283

		             A

		Sbjct: 1247 VA 1248

		

		

		

		 Score = 42.0 bits (98), Expect = 4e-06

		 Identities = 31/228 (13%), Positives = 64/228 (28%), Gaps = 4/228 (1%)

		

		Query: 59   AVVEQYKRMQSQESSAKRSDEQRKIKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKK 118

		            A  +  +  QS   + +    + K       E   EK   E E+ +++ K       +++

		Sbjct: 1078 ANTQTNEVAQSGSETKETQTTETKETATVEKE---EKAKVETEKTQEVPKVTSQVSPKQE 1134

		

		Query: 119  QAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKA 178

		            Q+E    QAE  ++       K             + A+E +        +        +

		Sbjct: 1135 QSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194

		

		Query: 179  AAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAAAEKAAADKKAAEKAAADKAAADKKAA 238

		              E  +    A       +E++       R+   +      + A   +      A     

		Sbjct: 1195 VVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSV-PHNVEPATTSSNDRSTVALCDLT 1253

		

		Query: 239  AEKAAADKKAAAAKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEADDI 286

		            +    A    A AKA        K  +   +  E     +      + 

		Sbjct: 1254 STNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYNVWVSNT 1301

		

		

		>OMPADOMAIN#OMPA domain signature.

		          Length = 346

		

		 Score =  116 bits (292), Expect = 5e-34

		 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 4/119 (3%)

		

		Query: 55  EEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSN--PSYKVTVEGHADER 112

		                +Q +     + V F+ +K  ++ +    LD   + L +       V V G+ D  

		Sbjct: 205 APAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRI 264

		

		Query: 113 GTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDEAAYSKNRRAVL 171

		           G+  YN  L ERRA +V  YL  KG+ AD+IS    G+  P V G+      K R A++

		Sbjct: 265 GSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNP-VTGN-TCDNVKQRAALI 321

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 29.0 bits (65), Expect = 0.025

		 Identities = 14/72 (19%), Positives = 28/72 (38%), Gaps = 4/72 (5%)

		

		Query: 24  AFAQAPISSVGSGSVEDRVTQLERISNAHSQLLTQLQQQLS---DNQSDIDSLRGQIQEN 80

		            F    I  +G+ +  D    +++    H  L     Q L     + + + S+R    E+

		Sbjct: 664 PFNMPAIVELGTATGFD-FELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLED 722

		

		Query: 81  QYQLNQVVERQK 92

		             Q    V+++K

		Sbjct: 723 TAQFKLEVDQEK 734

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 30.0 bits (67), Expect = 0.010

		 Identities = 9/18 (50%), Positives = 12/18 (66%)

		

		Query: 31  LVLLGPSGAGKSSLLRVL 48

		           +VL G  G GKS+L+  L

		Sbjct: 599 VVLEGTGGIGKSTLINTL 616

		

		

		>INTIMIN#Intimin signature.

		          Length = 939

		

		 Score = 30.0 bits (67), Expect = 0.006

		 Identities = 34/169 (20%), Positives = 58/169 (34%), Gaps = 4/169 (2%)

		

		Query: 13  ITVVCATSSVMAADDNAITDGKVTFNGKVIAPACTLVAATKDSVVTLPNVSATKL--QTN 70

		             +V  T+ + A   N    GK T   K   P   +V+A    + +  N +A     QT 

		Sbjct: 598 FNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTK 657

		

		Query: 71  GAVSGVKTDVPIALEGCDVTVTKNATFTFSGTADGVQPTAFANQATTDAATNVALQM--Y 128

		            +++ +K D   A+      +T              Q   F       + +        Y

		Sbjct: 658 ASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGY 717

		

		Query: 129 LPDGSTSVTPGTETSNIQLADSAEQTVTFKVDYIATGKATSGNVNAVTN 177

		                TS TPG    + +++D A      +V++  T     GN+  V  

		Sbjct: 718 AKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGT 766

		

		

		>CLENTEROTOXN#Clostridium enterotoxin signature.

		          Length = 319

		

		 Score = 31.9 bits (72), Expect = 0.004

		 Identities = 13/48 (27%), Positives = 22/48 (45%)

		

		Query: 295 VGVVVTDSQNNIISPAGGTLPLSIPDDADSIARMNVYPVSTTGVPPET 342

		           + V  TD +  I+  A  T  L++ D  +S    N+Y   ++   P T

		Sbjct: 188 LTVPSTDIEKEILDLAAATERLNLTDALNSNPAGNLYDWRSSNSYPWT 235

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 32.1 bits (73), Expect = 0.002

		 Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 12/82 (14%)

		

		Query: 55  RVARLRKNACLKYQATPEGLRYPASRGL----RAEQMRELLNGHYIIHR-----KNLLIT 105

		            +  +   A  + +  P  L   +  G+    R+  M+E+     ++ R       L+IT

		Sbjct: 110 ELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYR---VLARLMQTDLTLMIT 166

		

		Query: 106 GPTGCGKSWIANALGEQACRQK 127

		           G +G GK  +A AL +   R+ 

		Sbjct: 167 GESGTGKELVARALHDYGKRRN 188

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 97.6 bits (243), Expect = 7e-25

		 Identities = 67/305 (21%), Positives = 125/305 (40%), Gaps = 7/305 (2%)

		

		Query: 10  IASPFWGGLADRKGRKLMLLRSALGMGIVMVLMGLAQNIWQFLILRALLGLLGGFVPNAN 69

		             +P  G L+DR GR+ +LL S  G  +   +M  A  +W   I R + G+ G     A 

		Sbjct: 58  ACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG 117

		

		Query: 70  ALIATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYGLRPVFFITASVLILCFFV 129

		           A IA     ++     G +S     G + GP+ GGL+   +     FF  A++  L F  

		Sbjct: 118 AYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLT 176

		

		Query: 130 TLFCIREKFQPISKKEMLHMREVVTSLKNP---KLVLSLFVTTLIIQVATGSIAPILTLY 186

		             F + E  +   +         + S +      +V +L     I+Q+     A +  ++

		Sbjct: 177 GCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIF 236

		

		Query: 187 VRELAGNVSNVAFISGMIASVPGVAALLSAPRLGKLGDRIGPEKILITALIFSVLLLIPM 246

		             +      +   I   +A+   + +L  A   G +  R+G  + L+  +I      I +

		Sbjct: 237 GEDRFH--WDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILL 294

		

		Query: 247 SYVQTPLQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGPL 306

		           ++  T   +     +L A+ G  +PA+Q +L      +  G++     +   + ++ GPL

		Sbjct: 295 AFA-TRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPL 353

		

		Query: 307 MGAAI 311

		           +  AI

		Sbjct: 354 LFTAI 358

		

		

		

		 Score = 45.6 bits (108), Expect = 2e-07

		 Identities = 38/180 (21%), Positives = 73/180 (40%), Gaps = 3/180 (1%)

		

		Query: 156 LKNPKLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLS 215

		           +K  + ++ +  T  +  V  G I P+L   +R+L  + ++V    G++ ++  +     

		Sbjct: 1   MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHS-NDVTAHYGILLALYALMQFAC 59

		

		Query: 216 APRLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQT 275

		           AP LG L DR G   +L+ +L  + +    M+       L I R ++    GA       

		Sbjct: 60  APVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGR-IVAGITGATGAVAGA 118

		

		Query: 276 LLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAVYS 335

		            +   +      R F +  +    G V GP++G  +   +   A F   A +   N +  

		Sbjct: 119 YIADITDGDERARHFGFMSACFGFGMVAGPVLG-GLMGGFSPHAPFFAAAALNGLNFLTG 177

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 32.1 bits (73), Expect = 0.002

		 Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 12/82 (14%)

		

		Query: 55  RVARLRKNACLKYQATPEGLRYPASRGL----RAEQMRELLNGHYIIHR-----KNLLIT 105

		            +  +   A  + +  P  L   +  G+    R+  M+E+     ++ R       L+IT

		Sbjct: 110 ELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYR---VLARLMQTDLTLMIT 166

		

		Query: 106 GPTGCGKSWIANALGEQACRQK 127

		           G +G GK  +A AL +   R+ 

		Sbjct: 167 GESGTGKELVARALHDYGKRRN 188

		

		

		>FLGHOOKAP1#Flagellar hook-associated protein signature.

		          Length = 546

		

		 Score = 41.9 bits (98), Expect = 4e-06

		 Identities = 17/49 (34%), Positives = 29/49 (59%)

		

		Query: 353 TLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQILNTLVNLR 401

		            L+N     S V+L +E  N+   Q+ Y +NAQ ++T + I + L+N+R

		Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546

		

		

		

		 Score = 37.2 bits (86), Expect = 9e-05

		 Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 4/56 (7%)

		

		Query: 6  AVSGLNAAATNLDVIGNNIANSATYGFKSGTASFAD----MFAGSKVGLGVKVAGI 57

		          A+SGLNAA   L+   NNI++    G+   T   A     + AG  VG GV V+G+

		Sbjct: 7  AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62

		

		

		>FLGLRINGFLGH#Flagellar L-ring protein signature.

		          Length = 232

		

		 Score =  349 bits (897), Expect = e-126

		 Identities = 232/232 (100%), Positives = 232/232 (100%)

		

		Query: 1   MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60

		           MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY

		Sbjct: 1   MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60

		

		Query: 61  GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120

		           GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA

		Sbjct: 61  GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120

		

		Query: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180

		           RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF

		Sbjct: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180

		

		Query: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232

		           SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM

		Sbjct: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232

		

		

		>FLGPRINGFLGI#Flagellar P-ring protein signature.

		          Length = 373

		

		 Score =  426 bits (1096), Expect = e-151

		 Identities = 156/363 (42%), Positives = 212/363 (58%), Gaps = 9/363 (2%)

		

		Query: 4   FLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLN 63

		           F +   L      A   RI+D+ S+Q  R N LIGYGLVVGL GTGD    +PFT Q++ 

		Sbjct: 13  FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72

		

		Query: 64  NMLSQLGITVPTGTNMQLKNVAAVMVTESLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLM 123

		            ML  LGIT   G +   KN+AAVMVT +LPPF   G  +DV VSS+G+A SLRGG L+M

		Sbjct: 73  AMLQNLGITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIM 131

		

		Query: 124 TPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGN 183

		           T L G D Q+YA+AQG ++V G  A    +++        R+ NGA+IERELPS+F    

		Sbjct: 132 TSLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSV 191

		

		Query: 184 TLNLQLNDEDFSMAQQIADTINRVR----GYGSATALDARTIQVRVPSGNSSQVRFLADI 239

		            L LQL + DFS A ++AD +N       G   A   D++ I V+ P   +   R +A+I

		Sbjct: 192 NLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRV-ADLTRLMAEI 250

		

		Query: 240 QNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGG 299

		           +N+ V  T   AKVVIN RTG++V+  +V +   AV+ G L+V V     V QP  PF  

		Sbjct: 251 ENLTVE-TDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSR 308

		

		Query: 300 GQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLR 359

		           GQT V PQT I   Q G  + ++     L  +V  LN++G     +++ILQ ++SAG L+

		Sbjct: 309 GQTAVQPQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQ 367

		

		Query: 360 AKL 362

		           A+L

		Sbjct: 368 AEL 370

		

		

		>FLGFLGJ#Flagellar protein FlgJ signature.

		          Length = 313

		

		 Score =  511 bits (1318), Expect = 0.0

		 Identities = 313/313 (100%), Positives = 313/313 (100%)

		

		Query: 1   MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60

		           MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG

		Sbjct: 1   MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60

		

		Query: 61  LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120

		           LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET

		Sbjct: 61  LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120

		

		Query: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180

		           VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL

		Sbjct: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180

		

		Query: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240

		           ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL

		Sbjct: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240

		

		Query: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300

		           EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK

		Sbjct: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300

		

		Query: 301 VSKTYSMNIDNLF 313

		           VSKTYSMNIDNLF

		Sbjct: 301 VSKTYSMNIDNLF 313

		

		

		>FLGHOOKAP1#Flagellar hook-associated protein signature.

		          Length = 546

		

		 Score =  681 bits (1758), Expect = 0.0

		 Identities = 540/546 (98%), Positives = 543/546 (99%)

		

		Query: 2   SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 61

		           SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS

		Sbjct: 1   SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60

		

		Query: 62  GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 121

		           GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV

		Sbjct: 61  GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120

		

		Query: 122 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 181

		           SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND

		Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180

		

		Query: 182 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITVANGYSLVQGSTA 241

		           QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNIT+ANGYSLVQGSTA

		Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240

		

		Query: 242 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQELDQTRNTLGQL 301

		           RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQ+LDQTRNTLGQL

		Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300

		

		Query: 302 ALAFAEAFNTQHKAGFDANGDAGEDFFTIGKPAVLQNTKNKGDVAIGATVTDASVVLATD 361

		           ALAFAEAFNTQHKAGFDANGDAGEDFF IGKPAVLQNTKNKGDVAIGATVTDAS VLATD

		Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 360

		

		Query: 362 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 421

		           YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV

		Sbjct: 361 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 420

		

		Query: 422 NMDVLITDEAKIAMASEKDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 481

		           NMDVLITDEAKIAMASE+DAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN

		Sbjct: 421 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 480

		

		Query: 482 KTATLKTSSTTQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 541

		           KTATLKTSS TQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD

		Sbjct: 481 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 540

		

		Query: 542 ALINIR 547

		           ALINIR

		Sbjct: 541 ALINIR 546

		

		

		>FLAGELLIN#Flagellin signature.

		          Length = 507

		

		 Score = 45.4 bits (107), Expect = 2e-07

		 Identities = 41/226 (18%), Positives = 80/226 (35%), Gaps = 9/226 (3%)

		

		Query: 7   MMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPIAASQAVVLSQAQAQNSQYTLAR 66

		           ++ Q N+    +S +  +   E++S+G R+ +  DD    + A   +      +Q +   

		Sbjct: 11  LLTQNNLNKSQSSLSSAI---ERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNA 67

		

		Query: 67  TFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTLSDDDRASLATDIQGLRDQLLNLAN 126

		                     E  L+++   +Q  +E  V A+NGT SD D  S+  +IQ   +++  ++N

		Sbjct: 68  NDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSN 127

		

		Query: 127 TTDGNGRYIFAGYKTETAPFSEANGDYVGGTESIKQQVDASRSMVIGHTGDKIFDSITSN 186

		            T  NG  + +            +G      E+I   +       +G  G  +     + 

		Sbjct: 128 QTQFNGVKVLSQDNQMKIQVGANDG------ETITIDLQKIDVKSLGLDGFNVNGPKEAT 181

		

		Query: 187 AVAEPDGSASETNLFAMLDSAIAALKTPVADSEADKETAAAALDKT 232

		                    + T        A        + +     TA    DK 

		Sbjct: 182 VGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKV 227

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 68.2 bits (166), Expect = 2e-13

		 Identities = 49/261 (18%), Positives = 87/261 (33%), Gaps = 26/261 (9%)

		

		Query: 551  VAPAPKAATATPAAPAQPGLLSRFFGALKALFSGGEEAKPTEQP-TPKAEAKPERQQDRR 609

		                    T        P + S             E A+  E P  P A A P       

		Sbjct: 991  TVDTTNITTPNNIQADVPSVPSN----------NEEIARVDEAPVPPPAPATPSET---- 1036

		

		Query: 610  KPRQSNRRDRNERRDTRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEV------T 663

		                +     N ++++++      D  E   +NR  A++  +  + + Q  EV      T

		Sbjct: 1037 ----TETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET 1092

		

		Query: 664  EKARTTDEQQAPRRERSRRRNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQR 723

		            ++ +TT+ ++    E+  +   +  + Q+  K +  +    QE  +  + +    R    

		Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPK-VTSQVSPKQEQSETVQPQAEPARENDP 1151

		

		Query: 724  QLNQKVRYEQSVAEEAVVAPVVEETAAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEE 783

		             +N K    Q+        P  E ++  E  V E+    T    V  P     A  Q   

		Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTV 1211

		

		Query: 784  NNADNRDNGGMPRRSRRSPRH 804

		            N+  +       RRS RS  H

		Sbjct: 1212 NSESSNKPKNRHRRSVRSVPH 1232

		

		

		

		 Score = 60.8 bits (147), Expect = 2e-11

		 Identities = 48/288 (16%), Positives = 88/288 (30%), Gaps = 36/288 (12%)

		

		Query: 513  PSEEEFAERKRPEQPALATFAMPDVPPAPT-PAEPAATVVAPAPKAATATPAAPAQPGLL 571

		            P  E+  +               DVP  P+   E A    AP P  A ATP+   +    

		Sbjct: 983  PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE---- 1038

		

		Query: 572  SRFFGALKALFSGGEEAKPTEQPTPKAEAKPERQQDRRKPRQSNRRDRNERRDTRSER-- 629

		                    A     E +K   +   K E             Q+    +  + + ++    

		Sbjct: 1039 ------TVA-----ENSKQESKTVEKNEQDATE-----TTAQNREVAKEAKSNVKANTQT 1082

		

		Query: 630  TEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTTDEQQAPRRERSRRRNDDKRQ 689

		             E + +  E +  +    ++TA   +  +    TEK +   +  +    +  +    + Q

		Sbjct: 1083 NEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ 1142

		

		Query: 690  AQ---QEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSV--AEEAVVAPV 744

		            A+   +    +N++E   Q     +  +P   +     + Q V    +V      V  P 

		Sbjct: 1143 AEPARENDPTVNIKEPQSQTNTTADTEQPA--KETSSNVEQPVTESTTVNTGNSVVENPE 1200

		

		Query: 745  VEETAAAEPIVQEAPA------PRTELVKVPLPVVAQTAPEQQEENNA 786

		                A  +P V    +       R  +  VP  V   T         A

		Sbjct: 1201 NTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 30.4 bits (68), Expect = 0.007

		 Identities = 12/31 (38%), Positives = 18/31 (58%), Gaps = 4/31 (12%)

		

		Query: 27  LKPG----KILTLLGPNGAGKSTLVRVVLGL 53

		           ++PG      + L G  G GKSTL+  ++GL

		Sbjct: 589 MEPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619

		

		

		>ADHESNFAMILY#Adhesin family signature.

		          Length = 309

		

		 Score =  274 bits (702), Expect = 1e-93

		 Identities = 63/304 (20%), Positives = 114/304 (37%), Gaps = 25/304 (8%)

		

		Query: 4   KKTLLFAALSAALWGGATQA---------ADAAVVASLKPVGFIASAIADGVTETEVLLP 54

		           KK      L  +       A             VVA+   +  I   IA    +   ++P

		Sbjct: 2   KKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVP 61

		

		Query: 55  DGASEHDYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPGAKQVTIAQLEDVKPLL 114

		            G   H+Y   P DVK+   ADL+ + G  +E       +KL    + T    E+     

		Sbjct: 62  IGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKT----ENKDYFA 117

		

		Query: 115 MKSIHGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHGKLVELMPQSRAKLD 174

		           +             EK  ED H        WL+ E     A  I  +L    P ++   +

		Sbjct: 118 VSDGVDVIYLEGQNEKGKEDPH-------AWLNLENGIIFAKNIAKQLSAKDPNNKEFYE 170

		

		Query: 175 ANLKDFEAQLASTETQVGNELA--PLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQ 232

		            NLK++  +L   + +  ++    P + K       A+ YF K +G+     + +N E +

		Sbjct: 171 KNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEE 230

		

		Query: 233 PGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMGT---LDPLGTNIKLGK 289

		              +++  +  +L + K   +F E       +++V++ T++ +      D +    K G 

		Sbjct: 231 GTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGD 290

		

		Query: 290 TSYS 293

		           + YS

		Sbjct: 291 SYYS 294

		

		

		>ARGDEIMINASE#Bacterial arginine deiminase signature.

		          Length = 409

		

		 Score = 25.9 bits (57), Expect = 0.036

		 Identities = 10/37 (27%), Positives = 18/37 (48%), Gaps = 5/37 (13%)

		

		Query: 43 EVMLTCRPGNALYVINPSTLVQYPLNDI-----AQKE 74

		          + +L  RPG  L  + P  +  +  +DI     A++E

		Sbjct: 18 KKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQE 54

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 30.0 bits (67), Expect = 6e-04

		 Identities = 9/37 (24%), Positives = 17/37 (45%), Gaps = 5/37 (13%)

		

		Query: 4   LSWIIFGLIAGILAKWIMPG-----KDGGGFFMTILL 35

		            + I+ G I+G++  W+        K     ++ ILL

		Sbjct: 163 AAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILL 199

		

		

		>PRTACTNFAMLY#Pertactin virulence factor family signature.

		          Length = 910

		

		 Score = 27.7 bits (61), Expect = 0.022

		 Identities = 18/61 (29%), Positives = 26/61 (42%)

		

		Query: 49  QGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGS 108

		           Q  +I    L IG +  +    LPPS ++    N  ++ A      VS LG   +TL G 

		Sbjct: 174 QRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGG 233

		

		Query: 109 Q 109

		            

		Sbjct: 234 H 234

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  100 bits (249), Expect = 2e-27

		 Identities = 70/244 (28%), Positives = 114/244 (46%), Gaps = 16/244 (6%)

		

		Query: 2   IVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQ---LDVRNR 58

		           I  +TGA  G GE + R    QG  + A     E+L+++   L      A+    DVR+ 

		Sbjct: 10  IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69

		

		Query: 59  AAIEEMLASLPAEWCNIDILVNNAGLALGMEPAHKASVEDWETMIDTNNKGLVYMTRAVL 118

		           AAI+E+ A +  E   IDILVN AG+ L     H  S E+WE     N+ G+   +R+V 

		Sbjct: 70  AAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128

		

		Query: 119 PGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDIEPG 178

		             M++R  G I+ +GS     P      Y ++KA    F+  L  +L    +R   + PG

		Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188

		

		Query: 179 LVGGTEFSNVRFKGDDGKAE------KTYQNTVALT----PEDVSEAV-WWVSTLPAHVN 227

		               T+     +  ++G  +      +T++  + L     P D+++AV + VS    H+ 

		Sbjct: 189 ST-ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247

		

		Query: 228 INTL 231

		           ++ L

		Sbjct: 248 MHNL 251

		

		

		>PF05775#Enterobacteria AfaD invasin protein

		          Length = 142

		

		 Score = 29.5 bits (66), Expect = 0.007

		 Identities = 11/53 (20%), Positives = 17/53 (32%), Gaps = 7/53 (13%)

		

		Query: 106 THRLLLVELEGEKWIADVGFGGQTLTAPI-------RLVSDLVQTTPHGEYRL 151

		               L + + G  W + V  G Q +   I        +  D  Q    G+Y  

		Sbjct: 82  PQHNLRIRISGNGWSSFVEKGIQGVFNTIKEDASIFYIEVDGNQQVQPGKYLF 134

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 32.1 bits (73), Expect = 0.002

		 Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 12/82 (14%)

		

		Query: 55  RVARLRKNACLKYQATPEGLRYPASRGL----RAEQMRELLNGHYIIHR-----KNLLIT 105

		            +  +   A  + +  P  L   +  G+    R+  M+E+     ++ R       L+IT

		Sbjct: 110 ELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYR---VLARLMQTDLTLMIT 166

		

		Query: 106 GPTGCGKSWIANALGEQACRQK 127

		           G +G GK  +A AL +   R+ 

		Sbjct: 167 GESGTGKELVARALHDYGKRRN 188

		

		

		>ECOLIPORIN#E.coli/Salmonella-type porin signature.

		          Length = 383

		

		 Score =  582 bits (1501), Expect = 0.0

		 Identities = 312/388 (80%), Positives = 337/388 (86%), Gaps = 16/388 (4%)

		

		Query: 1   MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYFSDNSAKDGDQSYARLG 60

		           MK KVLAL+IPALLAAGAAHAAE+YNKDGNKLDLYGKVDGLHYFSD+S+KDGDQ+Y R+G

		Sbjct: 1   MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60

		

		Query: 61  FKGETQINDQLTGYGQWEYNIQANNTESSKNQSWTRLAFAGLKFADYGSFDYGRNYGVMY 120

		           FKGETQINDQLTGYGQWEYN+QAN TE     SWTRLAFAGLKF DYGSFDYGRNYGV+Y

		Sbjct: 61  FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120

		

		Query: 121 DIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFFGLVNGLNFAVQYQGNNEGAS 180

		           D+EGWTDMLPEFGGDSYT ADN+MTGRANGVATYRNTDFFGLV+GLNFA+QYQG NE  S

		Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180

		

		Query: 181 N-----GQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAYTSSDRTNDQVNH--TAA 233

		                 G    NNG D+R++NGDG+G+STTYD+GMGFSAGAAYT+SDRTN+QVN   T A

		Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGTIA 240

		

		Query: 234 GGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDS----DYAVANKTQNFEVTAQYQF 289

		           GGDKADAWTAGLKYDANNIYLATMYSETRNMTP+G +    D  VANKTQNFEVTAQYQF

		Sbjct: 241 GGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQF 300

		

		Query: 290 DFGLRPAVSFLMSKGRDLHAADGADNPAGVDDKDLVKYADVGATYYFNKNMSTYVDYKIN 349

		           DFGLRPAVSFLMSKG+DL       N    DDKDLVKYADVGATYYFNKN STYVDYKIN

		Sbjct: 301 DFGLRPAVSFLMSKGKDL-----TYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKIN 355

		

		Query: 350 LLDEDDSFYAANGISTDDIVALGLVYQF 377

		           LLD+DD FY   GISTDDIVALG+VYQF

		Sbjct: 356 LLDDDDPFYKDAGISTDDIVALGMVYQF 383