>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 30.2 bits (68), Expect = 0.007 Identities = 9/51 (17%), Positives = 24/51 (47%) Query: 138 LHAVDARVNELEELLPLLMKDKLLAKGVSHLLSSQLTRILRTHAAMSVLGH 188 + V+ +VN+ +P L + + +++ +S L +S + + A + Sbjct: 80 VSDVEEQVNQYLSKVPELEQKQNVSELLSLLSNSPNISLSQLKAYLEGKSE 130
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 142 bits (361), Expect = 7e-40 Identities = 83/387 (21%), Positives = 149/387 (38%), Gaps = 84/387 (21%) Query: 5 IGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGET------LVGQPAKRQA 58 + IDLGT N+ + + + E PS++A QD VG AK+ Sbjct: 13 LSIDLGTANTLIYVKGQGIV-LNE--------PSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 59 VTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAE 118 P N + AI+ + +D I F + + Sbjct: 64 GRTPGN-IAAIRPM-----------KDGVIADFFVTEK------------------MLQH 93 Query: 119 VLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALA 178 +K++ + P ++ VP +R+A +++ + AG +I EP AAA+ Sbjct: 94 FIKQVHS---NSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIG 150 Query: 179 YGL--DKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRL 236 GL + TG+ V D+GGGT ++++I ++ V + +GG+ FD + Sbjct: 151 AGLPVSEATGS---MVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEAI 198 Query: 237 INYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA----QQTDVNLPYITADATG 292 INY+ + G + AE+ K E+ SA + ++ + Sbjct: 199 INYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGV 245 Query: 293 PKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQD-AGLSVSDIDD--VILVGGQTRMPMV 349 P+ + + LE+L E + + + VAL+ SDI + ++L GG + + Sbjct: 246 PRGFTLN-SNEILEALQEP-LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNL 303 Query: 350 QKKVAEFFGKEPRKDVNPDEAVAIGAA 376 + + E G +P VA G Sbjct: 304 DRLLMEETGIPVVVAEDPLTCVARGGG 330
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 29.3 bits (65), Expect = 0.021 Identities = 26/118 (22%), Positives = 47/118 (39%), Gaps = 21/118 (17%) Query: 82 YGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQ-IINA 140 Y R PE +E + R YW + N P ++ +F+ + +F G ++ Sbjct: 158 YSRFPEVKELMESQMERLARPYWEKLRNRPDMY----YFKNYNFKRCYFGLNGGDCLVAK 213 Query: 141 G-----------QGEGRYSELLAINLLEQLLLRRMEA-----INESLHPPMDNRVREA 182 G QG +Y E + LE++L +++A I + +P +V A Sbjct: 214 GDDGRTFISFSLQGNSKYKEEMDAKKLEEILSLKVDANPDKYIKATGYPGYSEKVEVA 271
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 184 bits (468), Expect = 8e-53 Identities = 97/288 (33%), Positives = 139/288 (48%), Gaps = 21/288 (7%) Query: 309 LQQKALAGSTATTRVRFFWGTDIHGKPQVYGVHTGEGTPY-ENVRVANMQWNEQTQRYEF 367 + A+A ++ T + + G V + +G + V V +N T YE Sbjct: 341 VNLNAVAKASGTVDLPMRLTNEARGNTTTLSVVSTDGVSVPKAVPVRMAAYNATTGLYEV 400 Query: 368 T---PAHDVDGPLITWTPENPEHGNVPGHTGN--DRPPLEQPTILVTPIPDGTDTYSTPP 422 T + ++TWTP +P P T +P +TP+ +TY Sbjct: 401 TVPSTTAEAPPLILTWTPASPPGNQNPSSTTPVVPKPVPVYEGATLTPVKATPETY---- 456 Query: 423 FPVPDPKEFNDYILVFPAGSGIKPIYVYLKEDPRKLPGVVTGRGVPLSPGTRWLDMSVSN 482 P D I+ FPA SGIKPIYV + DPR +PG TG+G P+ WL ++ Sbjct: 457 -PGVITLP-EDLIIGFPADSGIKPIYVMFR-DPRDVPGAATGKGQPV--SGNWLG--AAS 509 Query: 483 NGNGAPIPAHIADKLRGREFKTFDEFREALWLEVSQDPELIAQFSSGNQTRIKQGLTAKA 542 G GAPIP+ IADKLRG+ FK + +FRE W+ V+ DPEL QF+ G+ ++ G Sbjct: 510 QGEGAPIPSQIADKLRGKTFKNWRDFREQFWIAVANDPELSKQFNPGSLAVMRDGGAPYV 569 Query: 543 PIDGWHYGPKEIVKKFQIHHRVAIEYGGSVYDIDNLRIVTPRLHDEIH 590 G + K +IHH+V + GG VY++ NL VTP+ H EIH Sbjct: 570 RESE-QAGGRI---KIEIHHKVRVADGGGVYNMGNLVAVTPKRHIEIH 613
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 54.0 bits (129), Expect = 2e-12 Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 1 MSQYPELIAQFSSGNQTRIKQGLIAKAPLEGWHYGTKEIVKKFHIYHRVAIEYSGGIYDI 60 ++ PEL QF+ G+ ++ G E G + K I+H+V + GG+Y++ Sbjct: 543 VANDPELSKQFNPGSLAVMRDGGAPYVR-ESEQAGGRI---KIEIHHKVRVADGGGVYNM 598 Query: 61 DNLR 64 NL Sbjct: 599 GNLV 602
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 26.4 bits (58), Expect = 0.013 Identities = 13/34 (38%), Positives = 18/34 (52%) Query: 1 MYDFKNKIEDYTEREFIELLGEFTNPTGDNAQLK 34 Y K I+D ++F + L EFT T N +LK Sbjct: 88 QYSLKETIQDLCAKDFHQKLKEFTEKTPKNQKLK 121
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 47.5 bits (112), Expect = 2e-10 Identities = 16/62 (25%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 1 MSQYPELIAQFSTGNQTRIKQGLIAKAPLEGWYYGSKEIVKEFHIYHSVAIECGGEIYDI 60 ++ PEL QF+ G+ ++ G E G + + I+H V + GG +Y++ Sbjct: 543 VANDPELSKQFNPGSLAVMRDGGAPYVR-ESEQAGGRI---KIEIHHKVRVADGGGVYNM 598 Query: 61 DN 62 N Sbjct: 599 GN 600
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.0 bits (78), Expect = 0.002 Identities = 42/281 (14%), Positives = 89/281 (31%), Gaps = 32/281 (11%) Query: 26 DKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAP 85 + V +T G S E+ + IVKEI V G+ + G +++ + AD Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 86 AQA--------EEKKEAAPAAA-----PAAAAAKDVNVPDIGSDEVEVTEILVKVG-DKV 131 Q+ + + + + P + ++ +EV L+K Sbjct: 139 TQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTW 198 Query: 132 EAEQSLITVEGDKASMEVPAPFAGTVKEIKVNVGDKVSTGSLIMVFEVAGEAGAAAPAAK 191 + ++ + DK E A + ++ +K + A + Sbjct: 199 QNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHK-QAIAKHAVLEQ 257 Query: 192 QEAAPAAAPASAAGVKDVNVPDIGGDEV-------------EVTEVMVKVGDKVAA-EQS 237 + A + + E+ + + + D + Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE 317 Query: 238 LITVEGDKASMEVPAPFAGVVKELKVN-VGDKVKTGSLIMI 277 L E + + + AP + V++LKV+ G V T +M+ Sbjct: 318 LAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Score = 29.8 bits (67), Expect = 0.034 Identities = 20/95 (21%), Positives = 35/95 (36%), Gaps = 3/95 (3%) Query: 230 DKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMIFEVEGAAPAAAP 289 + VA +T G S E+ +VKE+ V G+ V+ G +++ GA A Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAE-ADTL 137 Query: 290 AKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAEND 324 Q + A + + + + E D Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPD 172
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 29.2 bits (65), Expect = 0.021 Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 20/99 (20%) Query: 110 MVKIEGGEWL----VETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDQL-L 164 V +E G L + V L AV GL P +V + D++G L Sbjct: 176 TVTLEPGRALDEGQISAVVHLVSSAVA-----GLPPGNVTLV---------DQSGHLLTQ 221 Query: 165 SDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIG 203 S+ + AQL V + +RI L+ P++G G Sbjct: 222 SNTSGRDLNDAQLKFANDVESRIQRRIEAILS-PIVGNG 259
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 767 bits (1982), Expect = 0.0 Identities = 252/847 (29%), Positives = 420/847 (49%), Gaps = 37/847 (4%) Query: 18 SFCALLLSPCAISAEHVEYDNTFLMGQDAFNIDLSRYTEGNPTLPGVYDVSVYINDQPVI 77 + +S+ + ++ FL DLSR+ G PG Y V +Y+N+ + Sbjct: 31 FVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMA 90 Query: 78 NQSISFITLEGKKNAQACITLKNLLQFHINKPDINAENSILLQREGELGDCLDLANIIPQ 137 + ++F T + ++ C+T L +N ++ N + C+ L ++I Sbjct: 91 TRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLL------ADDACVPLTSMIHD 144 Query: 138 ASVHYDVNDQRLDINVPQAWVMKNYQNYVDSSLWENGINAAMLAYNVNAYHSEIP-DRKN 196 A+ DV QRL++ +PQA++ + Y+ LW+ GINA +L YN + + + Sbjct: 145 ATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNS 204 Query: 197 DSVYAAFNGGINLGAWRLRATGNYNWMTNVGS-----DYDFQNRYLQRDLASLRSQLIVG 251 Y G+N+GAWRLR +++ ++ S + N +L+RD+ LRS+L +G Sbjct: 205 HYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLG 264 Query: 252 ESYTTGETFDAVSIRGIRLYSDSRMLPPALASFAPIIHGVANTNAKVTITQGGYKIYETT 311 + YT G+ FD ++ RG +L SD MLP + FAP+IHG+A A+VTI Q GY IY +T Sbjct: 265 DGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNST 324 Query: 312 VPPGAFVIDDLSPSGYGSDLIITIEESDGIKRTFSQPFSSVIQMQRPGVGRWDISAGQVL 371 VPPG F I+D+ +G DL +TI+E+DG + F+ P+SSV +QR G R+ I+AG+ Sbjct: 325 VPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYR 384 Query: 372 KDD-IQNEPNLFQASYYYGLNNYLTGYTGIQITDNNYTAGLLGLGLNT-AYGAFSVDVTH 429 + Q +P FQ++ +GL T Y G Q+ D Y A G+G N A GA SVD+T Sbjct: 385 SGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLAD-RYRAFNFGIGKNMGALGALSVDMTQ 443 Query: 430 SDVQIPDDKTYRGQSYRISWNKLFEDTRTSLNIAAYRYSTQNYLGLNDALTLIDEVKHPE 489 ++ +PDD + GQS R +NK ++ T++ + YRYST Y D + E Sbjct: 444 ANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIE 503 Query: 490 -----QDLEPKNMRNYSRM---KNQVTVSINQPLKFEKKDYGSFYLAGSWSDYWADGQNN 541 ++PK Y+ + ++ +++ Q L + YL+GS YW + Sbjct: 504 TQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL----GRTSTLYLSGSHQTYWGTSNVD 559 Query: 542 TNYSIGYSNSASWGSYSISAQRSWSQ-DGGNEDSIYLSFSIPIEKLLGSEHRDS-GFQSI 599 + G + + ++++S + + G + + L+ +IP L S+ + S Sbjct: 560 EQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASA 619 Query: 600 DTQLNSDFNGSNQLSISSSGYSTENH-ISYSVNTGYSMMKSSDDLGYIGGYASYESPWGT 658 ++ D NG G E++ +SYSV TGY+ + +Y +G Sbjct: 620 SYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGN 679 Query: 659 LSSSVSASSDNSRQISFNTDGGFVLHSGGLTFSNDSFSDSDTLAVVQAPGAKGARINYGN 718 + S S D +Q+ + GG + H+ G+T +DT+ +V+APGAK A++ Sbjct: 680 ANIGYSHSDDI-KQLYYGVSGGVLAHANGVTLGQPL---NDTVVLVKAPGAKDAKVENQT 735 Query: 719 ST-IDRWGYGVTNALSPYHENRIALDINGLENDVELKSTSAITVPRQGSVVFAGFETVQG 777 D GY V + Y ENR+ALD N L ++V+L + A VP +G++V A F+ G Sbjct: 736 GVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVG 795 Query: 778 QSAIMNIKRTDGKNIPFAADIYDENGNIIGNVGQGGQAFVRGIEQQGNIRINWLDDGKPV 837 +M + + K +PF A + E+ G V GQ ++ G+ G +++ W ++ Sbjct: 796 IKLLMTLTH-NNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENA- 853 Query: 838 TCLAHYQ 844 C+A+YQ Sbjct: 854 HCVANYQ 860
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 510 bits (1314), Expect = 0.0 Identities = 293/296 (98%), Positives = 294/296 (99%) Query: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA Sbjct: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 Query: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR Sbjct: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 Query: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAHYEDFIRSMKPRFVKRGARPLLLT 180 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLA YEDFIRSMKPRFVKRGARPLLLT Sbjct: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 Query: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH Sbjct: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 Query: 241 DNSKDMDTLMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRILDNAIGGKA 296 DNSKDMD LMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVR+LDNAIGGKA Sbjct: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 298 bits (765), Expect = e-101 Identities = 97/347 (27%), Positives = 178/347 (51%), Gaps = 6/347 (1%) Query: 6 SEEKTEKPSAQKLRKAREEGQLPRSKDMGLAASLFAAFVVISSSFPWYADFVRESFISVH 65 S EKTE+P+ +K+R AR++GQ+ +SK++ A + A ++ +Y + + + Sbjct: 2 SGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLI-- 59 Query: 66 QYAQEINNPDV--IGQFLRHHLLILGKFILTLLPMPA-AALLSSLVPGGWLFLPKKILPD 122 A++ P + + + LL LL + A A+ S +V G+L + I PD Sbjct: 60 -PAEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPD 118 Query: 123 FSKISPLKGIGRLFSSEHLAETGKMTVKSVVVLVMLWVSLRNNFAAFLGLQALPFKLAIN 182 KI+P++G R+FS + L E K +K V++ +++W+ ++ N L L + Sbjct: 119 IKKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITP 178 Query: 183 DGLSLYASVMRNFVILFIFFALIDVPLAKALFTKGLKMTKQELKEEYKNQEGKPEVKARV 242 + +M + F+ ++ D + K LKM+K E+K EYK EG PE+K++ Sbjct: 179 LLGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKR 238 Query: 243 RRLQRQLAMGQIRKVVPKANVVITNPTHYAVALQYDQSRAAAPFVVAKGTDEIALYIRQV 302 R+ +++ +R+ V +++VV+ NPTH A+ + Y + P V K TD +R++ Sbjct: 239 RQFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKI 298 Query: 303 AAENQVEVVEFPRLARSVYYTTQVNQQIPFQLYRAIAHVLTYVLQMK 349 A E V +++ LAR++Y+ V+ IP + A A VL ++ + Sbjct: 299 AEEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQN 345
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 110 bits (277), Expect = 2e-31 Identities = 75/232 (32%), Positives = 126/232 (54%), Gaps = 2/232 (0%) Query: 8 QLTDLALGLWFPFVRIMAFLRYVPVLDNSALTVRVRIILSLALAIIITPLIPHPIPHDLL 67 Q ++P +R++A + P+L ++ RV++ L++ + I P +P + Sbjct: 8 QWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDV-PVF 66 Query: 68 SLNSLILTVEQILWGMLFGLMFQFLFLALQLAGQILSFNMGMSMAVMNDPSSGASTTVLA 127 S +L L V+QIL G+ G QF F A++ AG+I+ MG+S A DP+S + VLA Sbjct: 67 SFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLA 126 Query: 128 ELINVYAILLFFAMDGHLLLVSVLYKGFTYWPIGNA-LHPQTLRTIALAFSWVLASASLL 186 ++++ A+LLF +GHL L+S+L F PIG L+ + A S + + +L Sbjct: 127 RIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLML 186 Query: 187 ALPTTFIMLIVQGCFGLLNRIAPPLNLFSLGFPINMLAGLVCFATLLYNLPD 238 ALP ++L + GLLNR+AP L++F +GFP+ + G+ A L+ + Sbjct: 187 ALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAP 238
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 43.2 bits (102), Expect = 3e-09 Identities = 21/73 (28%), Positives = 36/73 (49%) Query: 14 GIKVVILLVSVLVVPSLLVGLLVSVFQAVTQINEQTLSFLPRLIVTLVVLGVCGKWMIIQ 73 + +V++L + + ++GLLV +FQ VTQ+ EQTL F +L+ + L + W Sbjct: 11 ALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLLSGWYGEV 70 Query: 74 LHDLCIHLFSQAA 86 L + A Sbjct: 71 LLSYGRQVIFLAL 83
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 223 bits (569), Expect = 2e-75 Identities = 111/243 (45%), Positives = 152/243 (62%), Gaps = 4/243 (1%) Query: 3 RRTQLALGLGLLALAPLALAQGGDIALLNVVTHGNTQEYSVKIQVLILMTLVGLLPTMVL 62 RR + L + PLA AQ + + G Q +S+ +Q L+ +T + +P ++L Sbjct: 2 RRLLSVAPVLLWLITPLAFAQLP--GITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILL 59 Query: 63 MMTCFTRFIIVLSLLRQALGLQQTPPNRILIGIALSLTMLVMRPVWLNIYDHAVVPFEND 122 MMT FTR IIV LLR ALG PPN++L+G+AL LT +M PV IY A PF + Sbjct: 60 MMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEE 119 Query: 123 QITLTDALSTAATPLKRFMLAQTDKKAMAQIMTIGGAKG--NAADQDLTIVVPAYVLSEL 180 +I++ +AL A PL+ FML QT + + + + I++PAYV SEL Sbjct: 120 KISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSEL 179 Query: 181 KTAFQIGFMIYIPFLVIDLIVASVLMAMGMMMLSPLIVSLPFKLMLFVLIDGWSLTIGTL 240 KTAFQIGF I+IPFL+IDL++ASVLMA+GMMM+ P ++LPFKLMLFVL+DGW L +G+L Sbjct: 180 KTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSL 239 Query: 241 TTS 243 S Sbjct: 240 AQS 242
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 71.1 bits (174), Expect = 5e-19 Identities = 39/104 (37%), Positives = 61/104 (58%), Gaps = 5/104 (4%) Query: 13 GLADEVAPVTKSADAETLVTRL----EDRFSDSMTLLKRIPVTLTLEVSSVEIMLADLLN 68 L ++ A TKSA A+ + +L + L+ IPV LT+E+ + + +LL Sbjct: 22 ALNEQKATTTKSA-ADAVFQQLGGGDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLR 80 Query: 69 IDDDTVIELDKLAGEPLDIKVNNILLGKAEVVVVNEKYGLRVLE 112 + +V+ LD LAGEPLDI +N L+ + EVVVV +KYG+R+ + Sbjct: 81 LTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRITD 124
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 361 bits (929), Expect = e-125 Identities = 112/345 (32%), Positives = 183/345 (53%), Gaps = 26/345 (7%) Query: 3 ELIATAASSINAFTLAKRVAAFNVPVLIQGETGAGKECVAKYIHTVAFGENDNAPYIGVN 62 L+ +A+ + + R+ ++ ++I GE+G GKE VA+ +H +G+ N P++ +N Sbjct: 138 PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALH--DYGKRRNGPFVAIN 195 Query: 63 CAAIPENMLESTLFGYDKGAFTGAIASVPGKMELANNGSLLLDEIGEMPLALQAKILRVL 122 AAIP +++ES LFG++KGAFTGA G+ E A G+L LDEIG+MP+ Q ++LRVL Sbjct: 196 MAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVL 255 Query: 123 QEQQVERLGSNRQIKLNFRLIACTNKNLEQEVAAGRFREDLYYRLAVIPITMPPLRERLN 182 Q+ + +G I+ + R++A TNK+L+Q + G FREDLYYRL V+P+ +PPLR+R Sbjct: 256 QQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAE 315 Query: 183 DIIPLAESFIKKYSTVLVKNITLSESTRRALLNYRWPGNVRQLENAIQRGMILNRDGVIY 242 DI L F+++ + + + + WPGNVR+LEN ++R L VI Sbjct: 316 DIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVIT 375 Query: 243 PDAL---------------------GLPDTDIADHSELQWPVQPAVHIAETGDLGQHGRS 281 + + L + + + Q+ + +G + Sbjct: 376 REIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAE 435 Query: 282 AQYQYIADLMRKYQGNRSKIADLLGITPRALRYRLASMRKHGIEV 326 +Y I + +GN+ K ADLLG+ LR + +R+ G+ V Sbjct: 436 MEYPLILAALTATRGNQIKAADLLGLNRNTLRKK---IRELGVSV 477
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 38.9 bits (90), Expect = 4e-07 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Query: 36 SSTDPDVSFNRIMSGALGHVDQFQQVAEQQQTAVDTGKSD-DLAGAMIASQQASLSFSAL 94 S P +SF + AL + Q A Q G+ L M Q+AS+S Sbjct: 25 SLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMG 84 Query: 95 VQVRNKIATGFNDLMSMSI 113 +QVRNK+ + ++MSM + Sbjct: 85 IQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 284 bits (727), Expect = 5e-91 Identities = 161/551 (29%), Positives = 255/551 (46%), Gaps = 37/551 (6%) Query: 18 RLADNKRWALMAGVGLAVAATAIIVSVLWTGNRGYVSLYGRQENLPVSQIVTVLDGEKLS 77 RL N R L V + A ++ VLW Y +L+ + IV L + Sbjct: 18 RLRANPRIPL--IVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIP 75 Query: 78 YRIDPQSGQILVPEDELSKTRMTLAAKGVQAILPSGYELMDKDEVLGSSQFVQNVRYKRS 137 YR SG I VP D++ + R+ LA +G+ G+EL+D+ E G SQF + V Y+R+ Sbjct: 76 YRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQ-EKFGISQFSEQVNYQRA 134 Query: 138 LEGELAQSIMSLDAVESARVHLALNEESSFVVSDEPQNSASVVVRLHYGAKLNMDQVNAI 197 LEGELA++I +L V+SARVHLA+ + S FV + SASV V L G L+ Q++A+ Sbjct: 135 LEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSP-SASVTVTLEPGRALDEGQISAV 193 Query: 198 VHLVSGSIPGLHASKVSVVDQAGNLLTDG-IGAGEAVSAATRKRDQILKDIQDKTRASVA 256 VHLVS ++ GL V++VDQ+G+LLT + A + + + IQ + + Sbjct: 194 VHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRIQRR----IE 249 Query: 257 NVLDSLVGSGNYRVSVMPDLDLSNIDETQEHY---GDAPKIN---REENVLDSDTNQVAM 310 +L +VG+GN V LD +N ++T+EHY GDA K R+ N+ + Sbjct: 250 AILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPG 309 Query: 311 GVPGSLSNRPPIAANQMTNGTEENR----------------SPEALSKHSESKRDYSYDR 354 GVPG+LSN+P N+ S S +Y DR Sbjct: 310 GVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDR 369 Query: 355 SVQHIQHPGFAVKRLNVAVVLN-QNAPALKN--WKPEQTTQLTALLNNAAGIDVQRGDNL 411 +++H + ++RL+VAVV+N + K +Q Q+ L A G +RGD L Sbjct: 370 TIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMGFSDKRGDTL 429 Query: 412 TLSLLNFVPQAVPVEPIIPLWKDDSVLAWVRLIGCGLLALLLLFFVVRPVMKRLTAVRAP 471 + F +P W+ S + + G LL L++ + + R ++ R Sbjct: 430 NVVNSPF-SAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLTRRVE 488 Query: 472 VITPEPEAVSEPWIAMPEEERKNVDLPSLPGDDSLPSQSSGLEVKLEFLQKLAMSDTDRV 531 E E + L + +Q G EV + +++++ +D V Sbjct: 489 EAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRA--NQRLGAEVMSQRIREMSDNDPRVV 546 Query: 532 AEVLRQWITSN 542 A V+RQW++++ Sbjct: 547 ALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 186 bits (473), Expect = 2e-58 Identities = 86/317 (27%), Positives = 170/317 (53%), Gaps = 2/317 (0%) Query: 14 EQAAILLLCLGEEAAATVMQKLSREEVVRLSENMARLSGVKTSMARKVINNFFDEFREQS 73 ++AAILL+ +G E ++ V + LS+EE+ L+ +A+L + + + V+ F + Q Sbjct: 19 QKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFKELMMAQE 78 Query: 74 GINGASRSMLQGILNKALGTEIASSVINGIYGDEIRSRMARLQWVEPRQLAMLISEEHLQ 133 I + +L K+LGT+ A +IN + ++ +P + I +EH Q Sbjct: 79 FIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILNFIQQEHPQ 138 Query: 134 LQAVFLAFLTPEISAAVLSYLNESVQNEILYRVAKLNDVNRDVVDELDRLIERGL-SVLS 192 A+ L++L P+ ++ +LS L VQ + R+A ++ + +VV E++R++E+ L S+ S Sbjct: 139 TIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEKKLASLSS 198 Query: 193 EHGSKVKGIKQAADIVNRFQGNQQ-VILDQMRERDEDVLEQLQDEMYDFFILSRQNEEVR 251 E + G+ +I+N + I++ + E D ++ E+++ +M+ F + ++ Sbjct: 199 EDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDIVLLDDRSI 258 Query: 252 RRLLDEVPMEDWAVALKGTEALLRRSIYAVMPKRQAQQLEAITARLGPVPVSRIEQIRRE 311 +R+L E+ ++ A ALK + ++ I+ M KR A L+ LGP +E+ +++ Sbjct: 259 QRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRKDVEESQQK 318 Query: 312 IMGIARELEEAGEIQLQ 328 I+ + R+LEE GEI + Sbjct: 319 IVSLIRKLEEQGEIVIS 335
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 56.0 bits (134), Expect = 1e-11 Identities = 44/187 (23%), Positives = 84/187 (44%), Gaps = 6/187 (3%) Query: 40 LMDGFQEGLQKGFAQGMTEGQEQGFSEGHQQGFAEGRRQGYTEGSLAGQQEGRKQFVDAA 99 +++ + L++ AQ + EQG+ G +G +G +QGY EG G ++G + Sbjct: 32 IIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQ 91 Query: 100 QPLEA----ISGKVNDFLAHIERKQREDLLQLVEKVTRQVIRCELALQPTQLLALVEEAL 155 P+ A + + L ++ L+Q+ + RQVI + + L+ +++ L Sbjct: 92 APIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLL 151 Query: 156 AAFPAMPETLQVMLSTEEFNRLRDAVPEKVS--EWGLTPSPDLPPGECRVITDKSELDIG 213 P Q+ + ++ R+ D + +S W L P L PG C+V D+ +LD Sbjct: 152 QQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDAS 211 Query: 214 CEHRLEQ 220 R ++ Sbjct: 212 VATRWQE 218
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 38.3 bits (89), Expect = 2e-06 Identities = 30/135 (22%), Positives = 55/135 (40%), Gaps = 20/135 (14%) Query: 8 GTFDVFHVGHLRLLQRARTLGERLLVGVSSDALNIAKKGRAPVYPQDDRMAIIAG-LACV 66 G+FD GHL +++R L +++ V V N K+ P++ +R+ IA +A + Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAV---LRNPNKQ---PMFSVQERLEQIAKAIAHL 60 Query: 67 DGVFLEESLEQKAEYLRGYSADILVMG-----D-----DWAGKFDSFAYICEVVYFPRTP 116 ++ Y R A ++ G D A + A E V+ + Sbjct: 61 PNAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTST 120 Query: 117 ---SVSTTGIIEVIR 128 +S++ + EV R Sbjct: 121 EYSFLSSSLVKEVAR 135
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 27.6 bits (61), Expect = 0.017 Identities = 7/37 (18%), Positives = 18/37 (48%) Query: 104 VNVVEQMADMMSASRDFETNVDVLNNVKSMQQSLLKL 140 VN+ E+ ++ + + N VL ++ +L+ + Sbjct: 509 VNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 38.8 bits (90), Expect = 3e-05 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 5/59 (8%) Query: 2 SYEIAATGLNAVNEQLDGISNNIANAGTVGYKS----MTTQFSAMYAGSQ-AMGVSVAG 55 A +GLNA L+ SNNI++ GY M S + AG GV V+G Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Score = 37.2 bits (86), Expect = 1e-04 Identities = 16/47 (34%), Positives = 24/47 (51%) Query: 352 TLSSGVLESSNVDITSELVNLMTAQRNYQANTKVIATSTQLDDALFQ 398 LS+ S V++ E NL Q+ Y AN +V+ T+ + DAL Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 40.3 bits (94), Expect = 4e-06 Identities = 19/93 (20%), Positives = 38/93 (40%), Gaps = 19/93 (20%) Query: 5 LWISKTGLSAQDAEMSAIANNIANVNTTGFKRDRVMFQDLFYQTQEAPGAMLDQNNIMPT 64 + + +GL+A A ++ +NNI++ N G+ R + M N+ + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTLGA 49 Query: 65 GLQFGSGVRIVGTQKT-----FTEGNVETTDNA 92 G G+GV + G Q+ + T ++ Sbjct: 50 GGWVGNGVYVSGVQREYDAFITNQLRAAQTQSS 82 Score = 38.8 bits (90), Expect = 2e-05 Identities = 9/45 (20%), Positives = 20/45 (44%) Query: 213 TLQDNALEGSNVDIVNEMVAMITVQRAYEMNAKMVSAADDMLQYI 257 L + S V++ E + Q+ Y NA+++ A+ + + Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDAL 542
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 136 bits (344), Expect = 4e-42 Identities = 63/189 (33%), Positives = 93/189 (49%), Gaps = 12/189 (6%) Query: 37 EAPPPADGRAGGVFET------GYNWSLTADRRAYRVGDILTVILEESTQSSKQAKTNFG 90 P P G +F++ GY L DRR +GD LT++L+E+ +SK + N Sbjct: 39 PVPGPTPVANGSIFQSAQPINYGYQ-PLFEDRRPRNIGDTLTIVLQENVSASKSSSANAS 97 Query: 91 KSNTVDIG---APTIFGHTKDKLSGSIDA--NRDFDGSATSQQQNSLRGEITVSVHAVQP 145 + + G P ++A F+G + N+ G +TV+V V Sbjct: 98 RDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLV 157 Query: 146 NGILEIRGEKWLTLNQGDEYIRLSGLVRADDIQNDNSVSSQRIADARISYAGRGALSDAN 205 NG L + GEK + +NQG E+IR SG+V I N+V S ++ADARI Y G G +++A Sbjct: 158 NGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQ 217 Query: 206 AAGWLTRLF 214 GWL R F Sbjct: 218 NMGWLQRFF 226
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 329 bits (844), Expect = e-113 Identities = 147/369 (39%), Positives = 219/369 (59%), Gaps = 15/369 (4%) Query: 10 IKAAVITVSL----ALPGVALAQSLESLVNVQGVRENQLVGYSLVVGLDGTGDK-NQVKF 64 I AA++ +L P A ++ + ++Q R+NQL+GY LVVGL GTGD F Sbjct: 7 IAAALVFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPF 66 Query: 65 TNQTITNMLRQFGVQLPNKIDPKVKNVAAVAVSATLPPMYSRGQTIDVTVSSIGDAKSIR 124 T Q++ ML+ G+ KN+AAV V+A LPP S G +DVTVSS+GDA S+R Sbjct: 67 TEQSMRAMLQNLGITTQGG-QSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLR 125 Query: 125 GGTLLLTQLHGADGEVYALAQGSVVVGGMNATGASGSSVTVNTPTAGLIPNGATVEREIP 184 GG L++T L GADG++YA+AQG+++V G +A G +++T T+ +PNGA +ERE+P Sbjct: 126 GGNLIMTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELP 184 Query: 185 SDFQMGDTITLNLKRPSFKDANNIAAAINASF-----GGIATAQSSTNVSVRAPTSPGAR 239 S F+ + L L+ P F A +A +NA IA + S ++V+ P Sbjct: 185 SKFKDSVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKP-RVADL 243 Query: 240 VAFMSQLDDVQVQAEKIRARVVFNSRTGTVVMGDGVALHAAAVSHGSLTVSINETSNVSQ 299 M++++++ V+ + A+VV N RTGT+V+G V + AVS+G+LTV + E+ V Q Sbjct: 244 TRLMAEIENLTVETDTP-AKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQ 302 Query: 300 PNAFAGGRTAVTPQSNIAVNHARPGVVSLPESSSLKTLVNALNSLGATPDDIMSILQALH 359 P F+ G+TAV PQ++I V++ E L+TLV LNS+G D I++ILQ + Sbjct: 303 PAPFSRGQTAVQPQTDIMA-MQEGSKVAIVEGPDLRTLVAGLNSIGLKADGIIAILQGIK 361 Query: 360 EAGALDADL 368 AGAL A+L Sbjct: 362 SAGALQAEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 57.0 bits (137), Expect = 3e-13 Identities = 26/75 (34%), Positives = 42/75 (56%), Gaps = 4/75 (5%) Query: 22 ANDIKQAAEQFEAIFLRNMLKEMRKTNELFDSKDNPFNSDSVRMMQGFYDDELCNTLAQQ 81 A +I+ A Q E +F++ MLK MR KD F+S+ R+ YD ++ + Sbjct: 30 AANIRPVARQVEGMFVQMMLKSMRDAL----PKDGLFSSEHTRLYTSMYDQQIAQQMTAG 85 Query: 82 HGIGIAAMIVKQLSP 96 G+G+A M+VKQ++P Sbjct: 86 KGLGLAEMMVKQMTP 100
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 176 bits (448), Expect = 1e-51 Identities = 97/326 (29%), Positives = 165/326 (50%), Gaps = 7/326 (2%) Query: 2 DMINIGYSGASTAQVELNVTAQNTANAMTTGYTRQVAEISTIGASGGSPNSAGNGVQVDS 61 +IN SG + AQ LN + N ++ GYTRQ ++ ++ G+ GNGV V Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Query: 62 IRRVSNQYQVNQVWYAASDYGYYSTQQGYLTQLEAVLSDDNSSLSGGFDNFFAALNEATT 121 ++R + + NQ+ A + + + +++++ +LS SSL+ +FF +L + Sbjct: 62 VQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVS 121 Query: 122 SPDDSALREQVISEAGALSLRIDNTLDYIDSQSTEIISQQQAMVSQINTLTSGIASYNQQ 181 + +D A R+ +I ++ L + T Y+ Q ++ A V QIN IAS N Q Sbjct: 122 NAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQ 181 Query: 182 IAQAEAN--GDNASALYDARDQMVEELSGMMDVQVNIDDQGNYNVTLKNGQPLVSGQQSS 239 I++ G + + L D RDQ+V EL+ ++ V+V++ D G YN+T+ NG LV G + Sbjct: 182 ISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTAR 241 Query: 240 TIA-LETNADGTPT----MSLTFAGTTSTMTTDTGGSLGALFDYQNDVLTPLTDTINSMA 294 +A + ++AD + T + T GSLG + +++ L +T+ +A Sbjct: 242 QLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLA 301 Query: 295 LQFADAVNNQLAQGYDLNGNPGEPLF 320 L FA+A N Q G+D NG+ GE F Sbjct: 302 LAFAEAFNTQHKAGFDANGDAGEDFF 327 Score = 74.2 bits (182), Expect = 3e-16 Identities = 54/286 (18%), Positives = 110/286 (38%), Gaps = 14/286 (4%) Query: 179 NQQIAQAEANGDNASALYDARDQMVEELSGMMDV-------QVNIDDQGNYNVTLKNGQP 231 N +I + N + + R Q +++ + N + ++ G+ Sbjct: 266 NIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNTQHKAGFDANGDAGED 325 Query: 232 LVSGQQSSTIALETNADGTPTMSLTFAGTTSTMTTDTGGSLGALFDYQNDVLTPLTDTI- 290 + + A+ N +++ T ++ T + + Q V ++T Sbjct: 326 FFAIGKP---AVLQNTKNKGDVAIGATVTDASAVLATDYKISFDNN-QWQVTRLASNTTF 381 Query: 291 NSMALQFADAVNNQLAQGYDLNGNPGEPLFIYDASNADGPLTVNPDITADELAFSSSPDE 350 + L + + + S+A + V A S Sbjct: 382 TVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAG 441 Query: 351 SGNSDNLQALINISTEPLEIANLGSVTVGQACSSIISNIGIYSQQNQTEVDAASNVYSEA 410 ++ N QAL+++ + G+ + A +S++S+IG + +T NV ++ Sbjct: 442 DSDNRNGQALLDLQSN--SKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQL 499 Query: 411 QNQQSSVSGVSMDEEAVNLITYQQIYEANLKVISAGAEIFDSVLEM 456 NQQ S+SGV++DEE NL +QQ Y AN +V+ IFD+++ + Sbjct: 500 SNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLAGELLIN#Flagellin signature. Length = 507 Score = 41.6 bits (97), Expect = 3e-06 Identities = 47/313 (15%), Positives = 99/313 (31%), Gaps = 12/313 (3%) Query: 1 MRVTTQQTYVSMTQSFNNLSGSLAHVVEQMATGKEILQPSDDPIAATRITQLNRQQSAIE 60 + T + + N SL+ +E++++G I DD + + Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLT 61 Query: 61 QYQSNIDSASAGLSQQESILDGVNNSLLAVRDDLLEAANGTNTADSLASLGQDIQSLTES 120 Q N + + E L+ +NN+L VR+ ++A NGTN+ L S+ +IQ E Sbjct: 62 QASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEE 121 Query: 121 MVAALNYQDEDGHYVFGGTINDQPPIVAVDDDGDGVT-----------DSYSYQGNSDHR 169 + N +G V + + A D + + D ++ G + Sbjct: 122 IDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEAT 181 Query: 170 QTTVSNGVEVDTNVAASDFFGSNLDV-LNTLNSLSQELQNPDVDPADPQVQSDLQNAVDV 228 + + + T + V +N+ ++ D + D Sbjct: 182 VGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDA 241 Query: 229 VDTASDDLNASIASLGETQNTMSMLSDAQTDISTSNDELIGSLQDLDYGPASITFTGLEV 288 + + DL + S T ++ + + G +D + + Sbjct: 242 ENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVST 301 Query: 289 AMEATLKTYSKVS 301 + T + Sbjct: 302 TINGEKVTLTVAD 314 Score = 37.7 bits (87), Expect = 4e-05 Identities = 27/262 (10%), Positives = 71/262 (27%), Gaps = 3/262 (1%) Query: 31 ATGKEILQPSDDPIAATRITQLNRQQSAIEQYQSNIDSASAGLSQQESILDGVNNSLLAV 90 +DD T + +S ++ + + ++ D + Sbjct: 229 VNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTID 288 Query: 91 RDDLLEAANGTNTADSLASLGQDIQSLTESMVAALNYQDEDGHYVFGGTINDQPPIVAVD 150 + +T + + + +T + V+ +N Q Sbjct: 289 TKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKT 348 Query: 151 DDGDGVTDSYSYQGNSDHRQTTVSNGVEVDTNVAASDFFGSNLDVLNTLNSLSQELQNPD 210 + ++ + V A + L + + Sbjct: 349 KNESAKLSDL---EANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTL 405 Query: 211 VDPADPQVQSDLQNAVDVVDTASDDLNASIASLGETQNTMSMLSDAQTDISTSNDELIGS 270 ++ + N + +D+A ++A +SLG QN + T+ + Sbjct: 406 INEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSR 465 Query: 271 LQDLDYGPASITFTGLEVAMEA 292 ++D DY + ++ +A Sbjct: 466 IEDADYATEVSNMSKAQILQQA 487
>FLAGELLIN#Flagellin signature. Length = 507 Score = 89.3 bits (221), Expect = 5e-22 Identities = 69/253 (27%), Positives = 122/253 (48%) Query: 4 INTNNASMAAVNAISKSSSSLSTSMERLATGNRINSSADDAAGKQIANRLTAQSSGMGVA 63 INTN+ S+ N ++KS SSLS+++ERL++G RINS+ DDAAG+ IANR T+ G+ A Sbjct: 4 INTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQA 63 Query: 64 LSNINDATAMLQTADSMFDEMSDVLGRMKDLSTQAANGTYSDDDLQAMQDEYDELGQQMS 123 N ND ++ QT + +E+++ L R+++LS QA NGT SD DL+++QDE + +++ Sbjct: 64 SRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEID 123 Query: 124 DMLQNTTYGGTNLFGVSGTSNTGTDGLFQSAVTFQVGAESSDTMTVNISSQLNTLVTDLS 183 + T + G + +T + ++ ++ + + Sbjct: 124 RVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATVG 183 Query: 184 AISNSFSADQADTTGTAGVSGGTELTASGSANQMITSISTAMDDVSQIQSKLGASINRLN 243 + +SF T G + SG+ T+ + + + + N Sbjct: 184 DLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAEN 243 Query: 244 DTANNLTSMQDNT 256 +TA +L +T Sbjct: 244 NTAVDLFKTTKST 256 Score = 65.1 bits (158), Expect = 5e-14 Identities = 55/273 (20%), Positives = 95/273 (34%), Gaps = 2/273 (0%) Query: 32 ATGNRINSSADDAAGKQIANRLTAQSSGMGVALSNINDATAMLQTADSMFDEMSDVLGRM 91 T + N++A D + TA++ + A+ + + + Sbjct: 237 TTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGN 296 Query: 92 KDLSTQAANGTYSDDDLQAMQDEYDELGQQMSDMLQNTTYGGTNLFGVSGTSNTGTDGLF 151 +ST + + + Y + T + Sbjct: 297 GKVSTTINGEKVTLTVADITAGAANVDAATLQS--SKNVYTSVVNGQFTFDDKTKNESAK 354 Query: 152 QSAVTFQVGAESSDTMTVNISSQLNTLVTDLSAISNSFSADQADTTGTAGVSGGTELTAS 211 S + + +TVN + D ++ +G + + A Sbjct: 355 LSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAK 414 Query: 212 GSANQMITSISTAMDDVSQIQSKLGASINRLNDTANNLTSMQDNTEVAIGNIMDTDYATE 271 S + SI +A+ V ++S LGA NR + NL + N A I D DYATE Sbjct: 415 KSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATE 474 Query: 272 ASNMTKQQVLMQTGITMLKQSNSMSSMVSSLLQ 304 SNM+K Q+L Q G ++L Q+N + V SLL+ Sbjct: 475 VSNMSKAQILQQAGTSVLAQANQVPQNVLSLLR 507
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 35.2 bits (80), Expect = 3e-04 Identities = 26/99 (26%), Positives = 45/99 (45%) Query: 236 LKDQIHFQLNKQQQISTIRLDPPSLGKLEIAVQLDNGKLMVHIGANQSEVCRALQQFSDD 295 L I + QQ + +RL P LG+++I++++D+ + + + + V AL+ Sbjct: 244 LSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAALPV 303 Query: 296 LRQHLTAQNFMEVNVQVSSEGQSQQQQQSGHQQEEVSAA 334 LR L +S E S QQQ + QQ+ A Sbjct: 304 LRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTA 342
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 550 bits (1418), Expect = 0.0 Identities = 232/384 (60%), Positives = 268/384 (69%), Gaps = 34/384 (8%) Query: 1 MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDIYGKVKAMHYMSDNDSKDGDQSYIRFG 60 MK+ LALV+ ++A+ + AAEIYNKDGNKLD+YGKV +HY SD+ SKDGDQ+Y+R G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGLKYKDLGSFDYGRNLGALY 120 FKGETQINDQLTGYG+WE N E + A TRLAFAGLK+ D GSFDYGRN G LY Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 121 DVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFGVIDGLNLTLQYQGKNEN-- 178 DVE WTDM PEFGGDS DN+MT RA+G+ATYRNTDFFG++DGLN LQYQGKNE+ Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 179 --------------RDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQNLQSR-- 222 D++ NGDGFG S TYD G F+ AYT SDRTNEQ Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDI-GMGFSAGAAYTTSDRTNEQVNAGGTI 239 Query: 223 GTGKRAEAWATGLKYDANNIYLATFYSETRKMTP-------ITGGFANKTQNFEAVAQYQ 275 G +A+AW GLKYDANNIYLAT YSETR MTP GG ANKTQNFE AQYQ Sbjct: 240 AGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQ 299 Query: 276 FDFGLRPSLGYVLSKGKDIE----GIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDS 331 FDFGLRP++ +++SKGKD+ D+DLV Y DVGATYYFNKN S +VDYKIN LD Sbjct: 300 FDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLLDD 359 Query: 332 DNKL----NINNDDIVAVGMTYQF 351 D+ I+ DDIVA+GM YQF Sbjct: 360 DDPFYKDAGISTDDIVALGMVYQF 383
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 37.5 bits (87), Expect = 6e-05 Identities = 28/127 (22%), Positives = 48/127 (37%), Gaps = 17/127 (13%) Query: 119 DTLRALLDNNI---------VPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLT 169 +T++ L++ + VPVI E+ + E V D D A AD ++LT Sbjct: 177 ETIKKLVERGVIVIASGGGGVPVILEDGEIKGVE-AVIDKDLAGEKLAEEVNADIFMILT 235 Query: 170 DQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAA-DVACRAG 228 D G + + +++V +++ + G M K+ AA G Sbjct: 236 DVNGAALY--YGTEKEQWLREV-KVEELRKYYEEG---HFKAGSMGPKVLAAIRFIEWGG 289 Query: 229 IDTIIAA 235 IIA Sbjct: 290 ERAIIAH 296 Score = 30.2 bits (68), Expect = 0.013 Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 13/76 (17%) Query: 4 SQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQ----LHAAGHRIVIVTSG-------- 51 + +V+ LG + L ++ + +++ VR+ A+ + A G+ +VI Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61 Query: 52 -AIAAGREHLGYPELP 66 + AG+ G P P Sbjct: 62 LHMDAGQATYGIPAQP 77
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 41.4 bits (97), Expect = 4e-06 Identities = 14/80 (17%), Positives = 28/80 (35%), Gaps = 12/80 (15%) Query: 2 IKILIVDDNKSRIEKLKSSLTELITKNMIRIDEKYTSDAAKIALKLNQYDYLILDVFLPK 61 IL+ DD+ + L +L ++ + + + D ++ DV +P Sbjct: 4 ATILVADDDAAIRTVLNQAL----SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMP- 58 Query: 62 KDNYSPDERNGLGLLKQINS 81 + N LL +I Sbjct: 59 -------DENAFDLLPRIKK 71
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.5 bits (87), Expect = 8e-06 Identities = 15/98 (15%), Positives = 36/98 (36%), Gaps = 16/98 (16%) Query: 2 KILLVEDIEYKRDKVIGLLESISADVSVDVAKSYVSAVNSATSKTYDLIILDMSLPTYDK 61 IL+ +D R + L A V + + + + DL++ D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSR--AGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN- 61 Query: 62 GPNENGGRFRVYGGKDIIRKLMRGKEHPVVVVLTQHTT 99 D++ ++ + + V+V++ T Sbjct: 62 -------------AFDLLPRIKKARPDLPVLVMSAQNT 86
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 25.6 bits (56), Expect = 0.043 Identities = 6/48 (12%), Positives = 12/48 (25%) Query: 42 LESWVRQLRRERQGIAPSATPITPEQQRIRELEKQVRRLEEQNTILKK 89 +W Q ++ + RI E R + + Sbjct: 195 FSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS 242
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 62.6 bits (152), Expect = 4e-12 Identities = 30/247 (12%), Positives = 72/247 (29%), Gaps = 23/247 (9%) Query: 487 TLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQNVYSGTFGSLGLRAGIQRYNNGDSS 546 L + + T +S + Y + +Q + F + N Sbjct: 530 QLTVTQQLGRTSTLYLSG-SHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQK 588 Query: 547 ANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGT------------IRTV 594 + +AL++++P +W + Q + A+ S + + Sbjct: 589 -GRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNL 647 Query: 595 GANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYINTNLTANGSVGWQGK 654 ++ +G + +G A + Y + + S +D +G V Sbjct: 648 SYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGY-SHSDDIKQLYYGVSGGVLAHAN 706 Query: 655 NIAASGRTDGNAGVIFNTGLED---DGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQ 711 + + ++ G +D + Q + + R G + Y V L Sbjct: 707 GVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR-----GYAVLPYATEYRENRVALD 761 Query: 712 NSKNSLD 718 + + + Sbjct: 762 TNTLADN 768
>INTIMIN#Intimin signature. Length = 939 Score = 546 bits (1409), Expect = e-177 Identities = 221/818 (27%), Positives = 358/818 (43%), Gaps = 49/818 (5%) Query: 41 PVMAARAQHAVQPRLSMGNTTVTADSNVEKNVASFAANAGTFLSSQPDS-----DATRNF 95 P++AA +L+ + VT + + ++AA L SQ S D ++ Sbjct: 131 PLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSRSLNGDYAKDT 190 Query: 96 ITGMATAKANQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAI 155 G+A +A+ ++Q WL YGTA V L +F SSL+ L P YD+ + F Q Sbjct: 191 ALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD--GSSLDFLLPFYDSEKMLAFGQVGA 248 Query: 156 HRTDDRTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGY 215 D R +N+G G R F M G N FID D S +TR+G+G EYWRDY K S NGY Sbjct: 249 RYIDSRFTANLGAGQRFFLPE-NMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGY 307 Query: 216 IRASGWKKSPDIEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQ 275 R SGW +S + +DY ERPANG+DIR GYLP++P LGA LMYEQYYGD V LF DK Q Sbjct: 308 FRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQ 367 Query: 276 KDPHAISAEVTYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLAKQLDTDSIRER 335 +P A + V YTP+PL+T+ ++ G END + ++ Y+ +P ++Q++ + E Sbjct: 368 SNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNEL 427 Query: 336 RMLAGSRYDLVERNNNIVLEYRKSEVIRIALPDRIAGKGGQTVSLGLVVSKATHGLKNVQ 395 R L+GSRYDLV+RNNNI+LEY+K +++ + +P I G T + L+V K+ +GL + Sbjct: 428 RTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTERSTQKIQLIV-KSKYGLDRIV 486 Query: 396 WEAPSLLAAGGKITGQG----NQWQVTLPAYQAGKDNYYAISAVAYDNKGNASKRVQTEV 451 W+ +L + GG+I G +Q LPAY G N Y ++A AYD GN+S V + Sbjct: 487 WDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNVLLTI 546 Query: 452 VITGAGMSAERTALTLDGQSRIQMLANGSEQKPLVLSLRDAEGQPVTGMKDQIKTELTFK 511 + G ++ +T + A+G+E +++ Q ++F Sbjct: 547 TVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNG-------VAQANVPVSFN 599 Query: 512 PAGNIVTRTLKATKSQAQPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDDMSKTVTA 571 + + + G + G+ ++ +M+ + A Sbjct: 600 IVSGTAVLSANSANTNGS-----------GKATVTLKSDK-PGQVVVSAKTAEMTSALNA 647 Query: 572 ELRATMMDVANSTLSANEPSGDVVADGQQSHTLTLTAVDTDGNPVTGEASRLRLVPQDTN 631 + S VA+GQ + T T+ V PV+ + T Sbjct: 648 NAVIFVDQTKASITEIKADKTTAVANGQDAITYTVK-VMKGDKPVSNQEVTF-----TTT 701 Query: 632 GVTVGAIS--EIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP-LDAAHS 688 + + G T++ST G +V A + ++F +D + Sbjct: 702 LGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNI 761 Query: 689 SITLNPDKPVVGGTVTAIWTAKDAYDNPVTSLTPE---APSLAGAAAVGSTASGWTNNGD 745 I V G + +W + + + + A+V +++ T Sbjct: 762 EIVGTG----VKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEK 817 Query: 746 GTWTAQITLGSTAGELDVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAEDHVKAGES 805 GT T + + N N +K DA+++ ++ E+ Sbjct: 818 GTTTISVISSDNQTATYTIATPNSL-IVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELEN 876 Query: 806 TTVTLIAKDAHGNAISGLSLSASLTGAASEGATVSSWT 843 A + + S ++ + + A + + + T Sbjct: 877 VFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVAST 914 Score = 76.3 bits (187), Expect = 6e-16 Identities = 69/373 (18%), Positives = 121/373 (32%), Gaps = 37/373 (9%) Query: 976 NGQNAVAQPLVLNVAGDAS-KAEIRDMTVKVDNQLANGQSTNQVTLTVVDTYGNPLQGQE 1034 N N V + + G + + D T + A+G T TV G Sbjct: 537 NSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKN-GVAQANVP 595 Query: 1035 VTLTLPQGVTSKTGNTVTTNAAGKADIELISTVAGELEIAAAVKNSQKTV---TVKFNAD 1091 V+ + G + N+ TN +GKA + L S G++ ++A + V F Sbjct: 596 VSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQ 655 Query: 1092 ASTGQANLQVDAAAQKVANGKDAFTLTANVEDKNGNPVPGSLVTFNLPRGVKPLTGDNVW 1151 ++ D VANG+DA T T V K PV VTF G + + Sbjct: 656 TKASITEIKADKTTA-VANGQDAITYTVKV-MKGDKPVSNQEVTFTTTLGKLSNSTE--- 710 Query: 1152 VKANDEGKAELQVVSVTAGTYEITASAGNDQPSDAQTITFVADKTTATVSGIEVIGNYAL 1211 K + G A++ + S T G ++A + T IE++G Sbjct: 711 -KTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGT--- 766 Query: 1212 ADGKAKQTYKVTVTDANNNLLK---DSEVTLTASPANLALDPDGTAKTNEQGQAIFTATT 1268 G + V + NL + + T ++ +A + + + + T + Sbjct: 767 --GVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISV 824 Query: 1269 TVAAKYTLTAKVEQANGQESTKTAESKFVADDKNAVLAASSDVTSLVADGVQTATMTVTL 1328 + T T + N+++ + D V T Sbjct: 825 ISSDNQTAT------------------YTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGK 866 Query: 1329 FSANNPVGGNVWV 1341 ++ NV+ Sbjct: 867 LPSSQNELENVFK 879 Score = 75.1 bits (184), Expect = 1e-15 Identities = 72/367 (19%), Positives = 120/367 (32%), Gaps = 45/367 (12%) Query: 882 TVIAGEMSSANSTLVADNKAP-TVKATTELTFTAKDAYGNPVSGLKLDAPVFSGAASTGS 940 V + ++ ++ AD T AT + PVS + +G+ Sbjct: 557 QVGVTDFTADKTSAKADGTEAITYTAT--VKKNGVAQANVPVSFNIV----------SGT 604 Query: 941 ERPSAGSWTEQSNGVYVATLTLGSAAGQLSVMPRVNGQNAVAQPLVLNVAGDASKAEIRD 1000 SA S +G TL + +A+ V+ V D +KA I + Sbjct: 605 AVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFV--DQTKASITE 662 Query: 1001 MTVKVDNQLANGQSTNQVTLTVVDTY-GNPLQGQEVTLTLPQGVTSKTGNTVTTNAAGKA 1059 + +ANGQ +T TV P+ QEVT T G S + T T+ G A Sbjct: 663 IKADKTTAVANGQDA--ITYTVKVMKGDKPVSNQEVTFTTTLGKLSNS--TEKTDTNGYA 718 Query: 1060 DIELISTVAGELEIAAAVKNSQ---KTVTVKFNADASTGQANLQVDAAAQKVANGKDAFT 1116 + L ST G+ ++A V + K V+F + N+++ V G Sbjct: 719 KVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEI------VGTGVKGKL 772 Query: 1117 LTANVEDKNGN-PVPGSLVTFNLPRGVKPLTGDNVWVKANDEGKAELQVVSVTAGTYEIT 1175 T ++ N G + N + + D QV GT I+ Sbjct: 773 PTVWLQYGQVNLKASGGNGKYT-------WRSANPAIASVDASSG--QVTLKEKGTTTIS 823 Query: 1176 ASAGNDQPSDAQTITFVADKTTATVSGIEVIGNYALADGKAKQTYKVTVTDANNNLLKDS 1235 + D QT T+ + + + D ++ N L++ Sbjct: 824 VISS-----DNQTATYTIATPNSLIV-PNMSKRVTYNDAVNTCKNFGGKLPSSQNELENV 877 Query: 1236 EVTLTAS 1242 A+ Sbjct: 878 FKAWGAA 884
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.029 Identities = 12/42 (28%), Positives = 19/42 (45%) Query: 3 RQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN 44 RQ IL L S+ +IA+ +G +R I F++ Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKD 54
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 430 bits (1106), Expect = e-155 Identities = 140/315 (44%), Positives = 201/315 (63%), Gaps = 3/315 (0%) Query: 1 MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASDYDIVLTHGNGPQVGLD 60 M + VV+A+GGN++ + S E + V+ A + E++A Y++V+THGNGPQVG Sbjct: 1 MGKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSL 60 Query: 61 LRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLARHG-EKKAVTVVTQVEVD 119 L + G+P P+ A +QG IGY+IQQAL N L + G EKK VT++TQ VD Sbjct: 61 LLHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVD 120 Query: 120 KNDPGFAHPTKPIGAFFSESQRDELQKANPDWRFVEDAGRGYRRVVASPEPKRIVEAPAI 179 KNDP F +PTKP+G F+ E L + W ED+GRG+RRVV SP+PK VEA I Sbjct: 121 KNDPAFQNPTKPVGPFYDEETAKRLAR-EKGWIVKEDSGRGWRRVVPSPDPKGHVEAETI 179 Query: 180 KALIQQGFVVIGAGGGGIPVVRTEAGDYQSVDAVIDKDLSTALLAREIHADILVITTGVE 239 K L+++G +VI +GGGG+PV+ E G+ + V+AVIDKDL+ LA E++ADI +I T V Sbjct: 180 KKLVERGVIVIASGGGGVPVIL-EDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVN 238 Query: 240 KVCIHFGKPQQQVLDRVDIATMTRYMQEGHFPPGSMLPKIIASLTFLEQGGKEVIITTPE 299 +++G ++Q L V + + +Y +EGHF GSM PK++A++ F+E GG+ II E Sbjct: 239 GAALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLE 298 Query: 300 CLPAALRGETGTHII 314 AL G+TGT ++ Sbjct: 299 KAVEALEGKTGTQVL 313
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 338 bits (868), Expect = e-113 Identities = 122/401 (30%), Positives = 200/401 (49%), Gaps = 54/401 (13%) Query: 164 DLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDMLGQSP 223 A +A G + Y ++ + + +L ++ ++G+S Sbjct: 88 MTAIKASEKGAYDYLPKPFDL--TELIGIIGRALAEPKRRPSK-LEDDSQDGMPLVGRSA 144 Query: 224 QMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSHPFVAVNC 283 M+++ + + ++ ++I GE+GTGKEL A+A+H + R+ PFVA+N Sbjct: 145 AMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD-----YGKRRNG---PFVAINM 196 Query: 284 GAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLPLQTRLLRVL 343 AI L+E+ELFG+E+GAFTG++ G FE A GGTLFLDEIG+MP+ QTRLLRVL Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTR-STGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVL 255 Query: 344 EEKEVTRVGGHQPVPVDVRVISATHCNLEEDMRQGEFRRDLFYRLSILRLQLPPLRERVT 403 ++ E T VGG P+ DVR+++AT+ +L++ + QG FR DL+YRL+++ L+LPPLR+R Sbjct: 256 QQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAE 315 Query: 404 DILPLAESFLKVSLAALSAPFSAALRQGLQASETVLVHYDWPGNIRELRNMMERLALFLS 463 DI L F++ ++ L+ + + WPGN+REL N++ RL Sbjct: 316 DIPDLVRHFVQ-QAEKEGLDVKRFDQEALEL----MKAHPWPGNVRELENLVRRLTALYP 370 Query: 464 VEP-TPDLTPQFLQLLLPELARESAKTPAPRLLTP------------------------- 497 + T ++ L+ +P+ E A + L Sbjct: 371 QDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYD 430 Query: 498 -----------QQALEKFNGDKTAAANYLGISRTTFWRRLK 527 AL G++ AA+ LG++R T ++++ Sbjct: 431 RVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIR 471
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.8 bits (67), Expect = 0.023 Identities = 11/33 (33%), Positives = 19/33 (57%), Gaps = 1/33 (3%) Query: 65 LIHGKLPTRDE-LAAYKTKLKALRGLPANVRTV 96 + +LPT +E AYK ++ + G P +RT+ Sbjct: 303 MDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTL 335
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.6 bits (82), Expect = 3e-04 Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 22/192 (11%) Query: 4 LKNTNFWMFGLFFFFYFFI-MGAYFPFFPIWLHDINHISK--SDTGIIFAAISLFSLLFQ 60 +K + L + +G P P L D+ H + + GI+ A +L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 61 PLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNA 120 P+ G LSD+ G R LL + + I P L + + +G IV GI A Sbjct: 61 PVLGALSDRFGRRPVLL---VSLAGAAVDYAIMATAPFL-WVLYIGRIVAGIT-----GA 111 Query: 121 GAPAVEAFIEKVSRRSNFEFGRARMFG----CVGWALCAS--IVGIMFTINNQFVFWLGS 174 A+I ++ RAR FG C G+ + A + G+M + F+ + Sbjct: 112 TGAVAGAYIADITDGDE----RARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAA 167 Query: 175 GCALILAVLLFF 186 + + F Sbjct: 168 ALNGLNFLTGCF 179
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 58.4 bits (141), Expect = 2e-11 Identities = 85/414 (20%), Positives = 152/414 (36%), Gaps = 51/414 (12%) Query: 1 MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQAFALDKMQMGWIFSAGI 60 M+T S+ + I LC L L+ ++ IA F W+ +A + Sbjct: 1 MNTSYSQSNLRHNQILIWLCILS-FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFM 59 Query: 61 LGLLPGALVGGMLADRYGRKRILIGSVALFGLFSLATAIAWD-FPSLVFARLMTGVGLGA 119 L G V G L+D+ G KR+L+ + + S+ + F L+ AR + G G A Sbjct: 60 LTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG-AA 118 Query: 120 ALPNLIA-LTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGFAGANLAWQTVFWVGGVVP 178 A P L+ + + RG A L+ V +G + +G A+ + + ++ Sbjct: 119 AFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMIT 178 Query: 179 LILVPLLMRWLPESAVFAGEKQ--------AAPPLRALFAPETATATLLLWLCYFFTLLV 230 +I VP LM+ L + G LF + + L++ + F + V Sbjct: 179 IITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL-IFV 237 Query: 231 VYMLINWLPLLLVEQGFQPSQAAGVMFA-LQMGAASGTLMLGALMDK------------- 276 ++ P + G GV+ + G +G + + M K Sbjct: 238 KHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSV 297 Query: 277 -LRPVTMSLLIYS---GMLAS------LLALGTVSSFNGMLLAGFV----------AGLF 316 + P TMS++I+ G+L +L +G L A F+ +F Sbjct: 298 IIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVF 357 Query: 317 ATGGQSVLYALAPLFYSSQIRATGVGTAVA----VGRLGAMSGPLLAGKMLALG 366 GG S + SS ++ G ++ L +G + G +L++ Sbjct: 358 VLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 28.2 bits (62), Expect = 0.020 Identities = 14/56 (25%), Positives = 30/56 (53%), Gaps = 2/56 (3%) Query: 11 LKAGLVTSKKAAKVERTAKKSRVQAREARAAVEENKKAQLERDKQLSEQQKQAALA 66 + +G + ++ + AK++ AR+ AVE N +AQ + Q + +Q++ L+ Sbjct: 308 IPSGELKDDIVEQIAQQAKEAGEVARQQ--AVESNAQAQQRYEDQHARRQEELQLS 361
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 30.0 bits (67), Expect = 0.015 Identities = 19/69 (27%), Positives = 30/69 (43%) Query: 254 DIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYF 313 + EL + +L + QV G A F +D E L I+ A +IF+ Sbjct: 466 NQFLELEKTKQLRLDTDQVYGNIATYNFENGRVRVDTGSNWSEVLPQIQETTARIIFNGK 525 Query: 314 ALDLAEKKI 322 L+L E++I Sbjct: 526 DLNLVERRI 534
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 52.5 bits (126), Expect = 1e-09 Identities = 73/356 (20%), Positives = 128/356 (35%), Gaps = 35/356 (9%) Query: 33 ILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGH---MISYYALGVVVGAPIIALF 89 + ++AL G+G+ IM VL L ++ S H +++ YAL AP++ Sbjct: 11 LSTVALDAVGIGL----IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 90 SSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIK 149 S R+ + +LL +A + A+ + +L IGR+V+G GA + I Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD--IT 124 Query: 150 PGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIVVMASVYFWVPDI 209 G A G +S ++ P+ L FS F A N + + F +P+ Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 210 RDEAKGKLREQ----------FHFLRSPAPWLI--FAATMFGNAGVFAWFSYVKPYMMFI 257 + LR + + A + F + G W + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG------E 238 Query: 258 SGFSETAMTFIMMLVGLGM---VLGNVLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCG 314 F A T + L G+ + +++G ++ R R + ++L F Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 315 GMKITSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAF--NLGSAVG 368 + I + G+ LQ +L + E G G +A +L S VG Sbjct: 299 RGWMAFPIMVLLASGGIG--MPALQAMLSRQV-DEERQGQLQGSLAALTSLTSIVG 351
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 38.9 bits (90), Expect = 1e-04 Identities = 40/264 (15%), Positives = 81/264 (30%), Gaps = 11/264 (4%) Query: 162 LNAKPKERAELLEELTGTEIYGKISAMVFEQHKSARTELEKLQAQASGVALLTPEQVQSL 221 A P E E + E + E S V + + A + + A Q+ Sbjct: 1029 APATPSETTETVAENSKQE-----SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTN 1083 Query: 222 TASLQVLTDEEKQLITAQQQEQQSLNWLTRLD-ELQQEGSRRQQALQQALAEEEKAQPQL 280 + +E Q ++ +++ E QE + + + E QPQ Sbjct: 1084 EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQA 1143 Query: 281 AALSLAQPARNLRPHWE---RIAEHSAALAHTRQQIEEVNTRLQSTMALRASIRHHAAKQ 337 P N++ A+ T +E+ T + + + + Sbjct: 1144 EPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203 Query: 338 SAELQQQQQSLNAWLQEHDRFRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLN 397 A Q S ++ ++ R + + ++DR + T+ L+ Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPA-TTSSNDRSTVALCDLTSTNTNAVLS 1262 Query: 398 ALAAITLTLTADEVASALAQHAEQ 421 A + + V A++QH Q Sbjct: 1263 DARAKAQFVALN-VGKAVSQHISQ 1285 Score = 37.0 bits (85), Expect = 5e-04 Identities = 28/140 (20%), Positives = 50/140 (35%), Gaps = 15/140 (10%) Query: 738 QQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQ 797 Q DV + S + A+ D A A E T T E KQ +++ Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPP-------APATPSETTETVAENSKQ-------ESK 1049 Query: 798 TLVTQTAEALAQHQQHRPDGLDLSVTVEQIQQELAQTQQKLRENTTSQGEIRQQLKQDAD 857 T+ +A Q+R + V+ Q Q T E ++ + + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 858 NRQQQQT-LMQQIAQMTQQV 876 + + +T Q++ ++T QV Sbjct: 1110 EKAKVETEKTQEVPKVTSQV 1129
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 81.8 bits (202), Expect = 5e-19 Identities = 77/362 (21%), Positives = 139/362 (38%), Gaps = 29/362 (8%) Query: 16 GLGTVFSLRMLGMFMVLPVLTTY--GMALQGASEALIGIAIGIYGLTQAVFQIPFGLLSD 73 L TV L +G+ +++PVL + A GI + +Y L Q G LSD Sbjct: 10 ILSTVA-LDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSD 68 Query: 74 RIGRKPLIVGGLAVFAAGSVIAALSDSIWGIILGRALQG-SGAIAAAVMALLSDLTREQN 132 R GR+P+++ LA A I A + +W + +GR + G +GA A A ++D+T Sbjct: 69 RFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDE 128 Query: 133 RTKAMAFIGVSFGITFAIAMVLGPIITHKLG---LHALFWMIAILATTGIALTIWVVPNS 189 R + F+ FG MV GP++ +G HA F+ A L +++P S Sbjct: 129 RARHFGFMSACFG----FGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 190 STHVLNRESGMVKGSFSKVLAEPRLLKLNFGIMCLHMLLMSTFVA-LPGQLADAGFPAAE 248 + + G+ + L+ F+ L GQ+ A + Sbjct: 185 HKGERRPLRREALNPLAS-------FRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG 237 Query: 249 HWKVYLATMLIAF--------GSVVPFIIYAEVKRKMKQVFVFCVGLIV-VAEIVLWNAQ 299 + + I S+ +I V ++ + +G+I +L Sbjct: 238 EDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFA 297 Query: 300 TQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAGYKGTAMGVYSTSQFLGVAIGGSLGG 359 T+ W + + + + + L +++S++ +G G + L +G L Sbjct: 298 TRGW-MAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFT 356 Query: 360 WI 361 I Sbjct: 357 AI 358
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 3e-05 Identities = 71/347 (20%), Positives = 135/347 (38%), Gaps = 20/347 (5%) Query: 62 KFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLEPGTQLRWMAALAVVIAFCS 121 +F +P++ + F RR LL + V A M W+ + ++A + Sbjct: 56 QFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAIMAT----APFLWVLYIGRIVAGIT 109 Query: 122 ASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSGGLALWLADKWLGWQGMYWLMA 181 + V A+ D+ +ER + GM+ L + ++ A Sbjct: 110 GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG--FSPHAPFFAAA 167 Query: 182 AL-LIPCIIATLLAPEP--TDTIPVPKTLEQAVVAPLRDFFGRNNAWLILLLIVLYKLGD 238 AL + + L PE + P+ + + + A L+ + ++ +G Sbjct: 168 ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQ 227 Query: 239 AFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYGGILMQRLSLFRALLIFGIL 298 A +L F +DA +G+ G+L ++ A+ G + RL RAL+ G++ Sbjct: 228 VPA-ALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALM-LGMI 285 Query: 299 QGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGTSAFVALLMTLCNKSFSATQFALLS 358 A GY LL+ + + V GG+G A A+L ++ L+ Sbjct: 286 --ADGTGYILLAFATRGWMAFPIMVLL--ASGGIGMPALQAMLSRQVDEERQGQLQGSLA 341 Query: 359 ALSAVGRVYVGPVAGWFVEAHGWSTF--YLFSVAAAVPGLILLLICR 403 AL+++ + VGP+ + A +T+ + + AA+ L L + R Sbjct: 342 ALTSLTSI-VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>PF06291#Lambda prophage Bor protein Length = 102 Score = 26.5 bits (58), Expect = 0.027 Identities = 11/34 (32%), Positives = 18/34 (52%) Query: 3 KKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQ 36 KK+LF ++ GCA+ T+ PT P++ Sbjct: 7 KKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKE 40
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1369 bits (3546), Expect = 0.0 Identities = 802/1033 (77%), Positives = 915/1033 (88%), Gaps = 1/1033 (0%) Query: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 M NFFI RPIFAWV+AII+M+AG LAIL+LPVAQYPTIAPPAV++SA+YPGADA+TVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 VTQVIEQNMNGIDNLMYMSS SDS G+V ITLTF+SGTD DIAQVQVQNKLQLA PLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 EVQQQG+SVEKSSSS+LMV G ++ + TQ+DISDYVA+N+KD +SR +GVGDVQLFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 QYAMRIW++ + LNK++LTPVDVI +K QN Q+AAGQLGGTP + GQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 + EEFGK+ L+VN DGS V L+DVA++ELGGENY++IA NG+PA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 DTA AI+A+LA+++PFFP G+K++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 E+ LPPKEAT KSM QIQGALVGIAMVLSAVF+PMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 SVLVALILTPALCAT+LKP++ H E K GFFGWFN F+ S +HYT+SVG IL STGR Sbjct: 481 SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 YL++Y +IV GM LF+RLPSSFLP+EDQGVF+TM+QLPAGATQERTQKVL++VT YYL Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 EK NVESVF VNGF F+G+ QN G+AFVSLK W +R G+EN EA+ RA +I+D Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 V FN+PAIVELGTATGFDFELIDQAGLGH+ LTQARNQLL AA+HP L SVRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 LEDT QFK+++DQEKAQALGVS++DIN T+ A GG+YVNDFIDRGRVKK+YV ++AK+R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 MLP+D+ YVR+A+G+MVPFSAF++S W YGSPRLERYNGLPSMEI G+AAPG S+G+A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 841 MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900 M LME LASKLP G+GYDWTGMSYQERLSGNQAP+L AIS +VVFLCLAALYESWSIP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 VMLVVPLG++G LLAAT NDVYF VGLLTTIGLSAKNAILIVEFAKDLM+KEGKG+ Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF 1020 +EATL AVRMRLRPILMTSLAFILGV+PL IS GAGSGAQNAVG GVMGGMV+AT+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1021 FVPVFFVVVRRRF 1033 FVPVFFVV+RR F Sbjct: 1020 FVPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.4 bits (105), Expect = 6e-07 Identities = 33/212 (15%), Positives = 71/212 (33%), Gaps = 23/212 (10%) Query: 112 TYQAAYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTA 171 + Y A +L + + Q+ Q +++ ++ L +Q + Sbjct: 256 EQENKYVEAVNELR--VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313 Query: 172 AKAAVETARINLAYTKVTSPISGRIGKSNV-TEGALVQNGQATALATVQQLDPIYVDVTQ 230 + + + +P+S ++ + V TEG +V + T + V + D + V Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALV 372 Query: 231 SSNDFLRLKQELA----------NGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVD 280 + D + KV I D I+ + G + ++++ Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLV---GKVKNINLDAIEDQRLGLVFNVIISIE 429 Query: 281 QTTGSITLRAIFPNPDHTLLPGMFVRARLEEG 312 + S + I L GM V A ++ G Sbjct: 430 ENCLSTGNKNIP------LSSGMAVTAEIKTG 455 Score = 34.4 bits (79), Expect = 7e-04 Identities = 24/125 (19%), Positives = 43/125 (34%), Gaps = 13/125 (10%) Query: 61 PLQITTELPGR-TSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQAAYDS 119 ++I G+ T + R E++P + I+ + KEG + G L ++ +A Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA---- 134 Query: 120 AKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETA 179 D K Q++ A+L RYQ L E ++ Sbjct: 135 ---DTLKTQSSLLQARLEQTRYQILS-----RSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 180 RINLA 184 +L Sbjct: 187 LTSLI 191
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 222 bits (567), Expect = 5e-76 Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.017 Identities = 19/125 (15%), Positives = 40/125 (32%), Gaps = 6/125 (4%) Query: 28 QNTAFARASSNGDLPTKADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRVKEE 87 N RA L + + L L+ + A L++ ++ E Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSR--LDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 88 TVQLRQKVAEAPEKMRQATAALTALSDVDND--EETRKIL--STLSLRQLETRVAQALDD 143 +LR ++ + + +A V E L +T ++ L +A+ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEER 324 Query: 144 LQNAQ 148 Q + Sbjct: 325 QQASV 329
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 38.5 bits (89), Expect = 9e-05 Identities = 40/251 (15%), Positives = 78/251 (31%), Gaps = 31/251 (12%) Query: 404 PLPETTSQVLAARQQLQRVQGATKAKKSEPAA----ATRARPVNNAALERLASVTDRVQA 459 P E +Q + + + P+ AR + A + A T Sbjct: 983 PEVEKRNQTVDTTN----ITTPNNIQADVPSVPSNNEEIARV-DEAPVPPPAPATPSETT 1037 Query: 460 RPVPSALEKAPAKKEAYRWKATTPVMQQKE--------VVATPKALKKA---LEHEKTPE 508 V ++ E AT Q +E V A + + A E ++T Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 509 LAAKLAA---------EAIERDPWAAQVSQLSLPKLVEQVALNAWKE-ESDNAVCLHLRS 558 K A E+ +V+ PK + + E +N ++++ Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 559 SQRHLNNRGAQQKLAEALST-LKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARES 617 Q N ++ A+ S+ ++ E T V N V P A + + + Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 618 IIADNNIQTLR 628 + + +++R Sbjct: 1218 KPKNRHRRSVR 1228
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 31.6 bits (71), Expect = 0.009 Identities = 24/108 (22%), Positives = 46/108 (42%), Gaps = 12/108 (11%) Query: 422 RMKEGQEK--IYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKP 479 R+ G++K +I D +A + + G + ++ + + MMN + EF P Sbjct: 99 RLFNGRDKDSTSFILGDEFAVLR-------FYRNGESISYIAYK-EAQMMNEIAEFYAAP 150 Query: 480 FQSVSKV--DESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKD 525 F+ + E+ E + D SA + ++ ID+ K +L D Sbjct: 151 FKKTRAINEKEAFECIYDSRTRSAGKDIVSVKINIDKAKKILNLPECD 198
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.9 bits (70), Expect = 0.008 Identities = 37/167 (22%), Positives = 57/167 (34%), Gaps = 14/167 (8%) Query: 52 QSEFSLTFMQIGMITLTFQLASSLLQ-----PVVGYWTDKYPMPWSLPIGMCFTLSGLVL 106 + F IG+ F + SL Q PV ++ + + G +L Sbjct: 238 EDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGT----GYIL 293 Query: 107 LALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFGSSLGPL 166 LA A L+ +G + ++R R G Q + S +GPL Sbjct: 294 LAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPL 353 Query: 167 LAAVIIA---PYGKGNVAWFVLAALLAIVVLA-QISRWYSAQHRMNK 209 L I A G AW AAL + + A + W A R ++ Sbjct: 354 LFTAIYAASITTWNG-WAWIAGAALYLLCLPALRRGLWSGAGQRADR 399 Score = 30.2 bits (68), Expect = 0.017 Identities = 32/133 (24%), Positives = 50/133 (37%), Gaps = 2/133 (1%) Query: 267 LHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIG 326 L L+A + A + G + D+ GR+ V+ S+ G A I+ A W + I+ Sbjct: 49 LALYALMQFACAP--VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVA 106 Query: 327 FILASAFSAILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIELVYKIC 386 I + + Y ++ G F FG G + VLG + S + Sbjct: 107 GITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAA 166 Query: 387 AFLPLLGMLTIFL 399 A L L LT Sbjct: 167 AALNGLNFLTGCF 179 Score = 29.8 bits (67), Expect = 0.018 Identities = 51/319 (15%), Positives = 111/319 (34%), Gaps = 24/319 (7%) Query: 43 LILAIYPLLQSEFSLTFMQI---GMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCF 99 LI+ + P L + + G++ + L PV+G +D++ L + + Sbjct: 23 LIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAG 82 Query: 100 TLSGLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRH----GLAQSIFQV 155 ++A A + + + G + + +A + G G + F Sbjct: 83 AAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGF 142 Query: 156 GGNFGSSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKAT 215 G G LG L+ A F AA L + H+ + + Sbjct: 143 GMVAGPVLGGLMGGF-------SPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRRE 195 Query: 216 IINPLPRNKVVLAVSILLILIFSKYFYMASISSY----YTFYLMQKFGLSIQNAQLHLFA 271 +NPL + ++++ L+ +F M + + + +F + L A Sbjct: 196 ALNPLASFRWARGMTVVAALMAV-FFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAA 254 Query: 272 F-LFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILA 330 F + A +I GPV ++G + + ++ ++L +A+ W +L Sbjct: 255 FGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW----MAFPIMVLL 310 Query: 331 SAFSAILVYAQELLPGRIG 349 ++ + Q +L ++ Sbjct: 311 ASGGIGMPALQAMLSRQVD 329
>PF03895#Serum resistance protein DsrA. Length = 79 Score = 55.2 bits (133), Expect = 3e-12 Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Query: 262 RKEANAGTASAIAIASQPQVKTGDVMMVSAGAGTFNGESAVSVGTSFNAGTHTVLKAGIS 321 KE G A+ A++ Q VSA G + ++A+++G KAG++ Sbjct: 2 SKELQTGLANQSALSMLVQPNGVGKTSVSAAVGGYRDKTALAIGVGSRITDRFTAKAGVA 61 Query: 322 ADTQS-DFGAGVGVGYSF 338 +T + G VGY F Sbjct: 62 FNTYNGGMSYGASVGYEF 79
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 74.7 bits (183), Expect = 5e-18 Identities = 48/212 (22%), Positives = 80/212 (37%), Gaps = 7/212 (3%) Query: 3 KSVLITGCSSGIGLESALELKRQGFHVLAGCRKADDVERMNS----MGFT--GVLIDLDS 56 K ITG + GIG A L QG H+ A + +E++ S D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 57 PESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRVQMEQQFSANFFGAHQLTMRL 116 ++D + + + N AG G + ++S + E FS N G + + Sbjct: 69 SAAIDEITARIEREMGP-IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 117 LPVMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEP 176 M+ G IV S + AYA+SK A ++ L +EL I+ +++ P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 177 GPIRTRFTDNVNQTQSDKPVENPGIAARFTLG 208 G T ++ ++ G F G Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTG 219
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.013 Identities = 12/20 (60%), Positives = 13/20 (65%) Query: 41 LVGESGSGKSTLLAILAGLD 60 L G G GKSTL+ L GLD Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 381 bits (981), Expect = e-136 Identities = 126/310 (40%), Positives = 175/310 (56%), Gaps = 16/310 (5%) Query: 2 KTLVVALGGNALLQRGEALTAENQYRNIASAVPALARL-ARSYRLAIVHGNGPQVGLLAL 60 K +V+ALGGNAL QRG+ + E N+ +A + AR Y + I HGNGPQVG L L Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62 Query: 61 QNLAWKE---VEPYPLDVLVAESQGMIGYMLVQSLSAQPQM----PPVTTVLTRIEVSPD 113 A + + P+DV A SQG IGYM+ Q+L + + V T++T+ V + Sbjct: 63 HMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKN 122 Query: 114 DPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRD-GKYLRRVVASPQPRNILDSEAIELL 172 DPAF P K +GP Y E + L GW +K D G+ RRVV SP P+ +++E I+ L Sbjct: 123 DPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKL 182 Query: 173 LKEGHVVICSGGGGVPVTDDG---VGSEAVIDKDLAAALLAEQINADGLVILTDADAVYE 229 ++ G +VI SGGGGVPV + G EAVIDKDLA LAE++NAD +ILTD + Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 230 NWGTPQQRAIRHATPDELAPLAKAD----GSMGPKVTAVSGYVRSRGKPAWIGALSRIEE 285 +GT +++ +R +EL + GSMGPKV A ++ G+ A I L + E Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVE 302 Query: 286 TLAGEAGTCI 295 L G+ GT + Sbjct: 303 ALEGKTGTQV 312
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.036 Identities = 16/150 (10%), Positives = 43/150 (28%), Gaps = 8/150 (5%) Query: 299 RSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMNDDFNTP----- 353 + ++ +L QAR R R + P E F ++ Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 354 EAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEV 413 E +S + + + A + + + + + + + + F + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS---LLHKQAI 249 Query: 414 AEIEALIQQRLDARKAKDWAAADAARDRLN 443 A+ L Q+ + + +++ Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIE 279
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 826 bits (2136), Expect = 0.0 Identities = 404/856 (47%), Positives = 572/856 (66%), Gaps = 20/856 (2%) Query: 20 ICYSSLAILPSFLSYAESYFNPAFLLENGTSVADLSRFERGNHQPAGVYRVDLWRNDEFI 79 + A + LS AE YFNP FL ++ +VADLSRFE G P G YRVD++ N+ ++ Sbjct: 31 FVACAFA-AQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYM 89 Query: 80 GSQDIVFESTTVNTGDKSGGLMPCFNQALLERIGLNSSAFPELAQQQNNKCINLLKAVPD 139 ++D+ F NTGD G++PC +A L +GLN+++ + ++ C+ L + D Sbjct: 90 ATRDVTF-----NTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHD 144 Query: 140 ATINFDFAAMRLNITIPQIALLSSAHGYIPPEEWDEGIPALLLNYNFTGN----RGNGND 195 AT D RLN+TIPQ + + A GYIPPE WD GI A LLNYNF+GN R GN Sbjct: 145 ATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNS 204 Query: 196 SYFFSEL-SGINIGPWRLRNNGSWNYFRGNG--YHSEQWNNIGTWVQRAIIPLKSELVMG 252 Y + L SG+NIG WRLR+N +W+Y + +W +I TW++R IIPL+S L +G Sbjct: 205 HYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLG 264 Query: 253 DGNTGSDIFDGVGFRGVRLYSSDNMYPDSQQGFAPTVRGIARTAAQLTIRQNGFIIYQSY 312 DG T DIFDG+ FRG +L S DNM PDSQ+GFAP + GIAR AQ+TI+QNG+ IY S Sbjct: 265 DGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNST 324 Query: 313 VSPGAFEITDLHPTSSNGDLDVTIDERDGNQQNYTIPYSTVPILQREGRFKFDLTAGDFR 372 V PG F I D++ ++GDL VTI E DG+ Q +T+PYS+VP+LQREG ++ +TAG++R Sbjct: 325 VPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYR 384 Query: 373 SGNSQQSSPFFFQGTALGGLPQEFTAYGGTQLSANYTAFLLGLGRNLGNWGAVSLDVTHA 432 SGN+QQ P FFQ T L GLP +T YGGTQL+ Y AF G+G+N+G GA+S+D+T A Sbjct: 385 SGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQA 444 Query: 433 RSQLADDSRHEGDSIRFLYAKSMNTFGTNFQLMGYRYSTQGFYTLDDVAYRRMEGYEYDY 492 S L DDS+H+G S+RFLY KS+N GTN QL+GYRYST G++ D Y RM GY Sbjct: 445 NSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGY-NIE 503 Query: 493 DYDGEHRDEPIIVNYHNLRFSRKDRLQLNISQSLNDFGSLYISGTHQKYWNTSDSDTWYQ 552 DG + +P +Y+NL ++++ +LQL ++Q L +LY+SG+HQ YW TS+ D +Q Sbjct: 504 TQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQ 563 Query: 553 VGYTSSWVGISYSLSFSWNESVGIPDNERIVGLNVSVPFNVLTKRRYTRENALDRAYASF 612 G +++ I+++LS+S ++ ++++ LNV++PF+ R ++ A AS+ Sbjct: 564 AGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWL--RSDSKSQWRHASASY 621 Query: 613 NANRNSNGQNNWLAGVGGTLLEGHNLSYHVSQG----DTSNNGYTGSATANWQAAYGTLG 668 + + + NG+ LAGV GTLLE +NLSY V G N+G TG AT N++ YG Sbjct: 622 SMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNAN 681 Query: 669 VGYNYDRDQHDVNWQLSGGVVGHENGITLSQPLGDTNVLIKAPGAGGVRIENQTGILTDW 728 +GY++ D + + +SGGV+ H NG+TL QPL DT VL+KAPGA ++ENQTG+ TDW Sbjct: 682 IGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDW 741 Query: 729 RGYAVMPYATVYRYNRIALDTNTMGNSIDVEKNISSVVPTQGALVRANFDTRIGVRALIT 788 RGYAV+PYAT YR NR+ALDTNT+ +++D++ +++VVPT+GA+VRA F R+G++ L+T Sbjct: 742 RGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMT 801 Query: 789 VTQGGKPVPFGSPVRENSTGITSMVGDDGQVYLSGAPLSGELLVQWGDGANSRCIAHYVL 848 +T KP+PFG+ V S+ + +V D+GQVYLSG PL+G++ V+WG+ N+ C+A+Y L Sbjct: 802 LTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQL 861 Query: 849 PKQSLQQAVTVISAVC 864 P +S QQ +T +SA C Sbjct: 862 PPESQQQLLTQLSAEC 877
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 268 bits (685), Expect = 6e-94 Identities = 106/183 (57%), Positives = 130/183 (71%), Gaps = 1/183 (0%) Query: 1 MKTTHTALPFAGNTLHFVKFDPASFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYA 60 M T+H LPFAG+ LH V FD +SF E DLLWLPH+ +L+ AGRKRK EHLAGRIAAV+A Sbjct: 1 MLTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA 60 Query: 61 LREYGYKCVPAIGELRQPVWPAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSAQTAAEL 120 LRE G + VP +G+ RQP+WP G++GSISHC TTALAV+SRQ IGIDIE+I S TA EL Sbjct: 61 LREVGVRTVPGMGDKRQPLWPDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATEL 120 Query: 121 TDNIITPAEHKRLADCGLAFSLALTLAFSAKESAFKA-CERQTDAGFLDYQIINWNKQQV 179 +II E + L L F LALTLAFSAKES +KA +R T GF ++ + + Sbjct: 121 APSIIDSDERQILQASLLPFPLALTLAFSAKESVYKAFSDRVTLPGFNSAKVTSLTATHI 180 Query: 180 IIH 182 +H Sbjct: 181 SLH 183
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.3 bits (84), Expect = 2e-04 Identities = 82/394 (20%), Positives = 145/394 (36%), Gaps = 38/394 (9%) Query: 27 FISIVSLGLLGVAVPVQIQMMTHSTWQV---GLSVTLTGGAMFVGLMVGGVLADRYERKK 83 + V +GL+ +P ++ + HS G+ + L F V G L+DR+ R+ Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 84 VILLARGTCGIGFIGLCLNALL--PEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGR 141 V+L + G ++ + P L +Y+ + G + G A A + Sbjct: 75 VLL-------VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA-GAYIADITDG 126 Query: 142 ENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPP 201 + + G V P++GGL+ GG + + AA L L LP Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLM---GGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 202 PPQPREHPLK----SLLAGFRFLLASPLVGGIALLGGLLTMAS----AVRVLYPALADNW 253 + PL+ + LA FR+ +V + + ++ + A+ V++ D + Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG--EDRF 241 Query: 254 QMSAAQIGFLYAAIP-LGAAIGALTSGKLAHSARPGLLMLLSTLGS---FLAIGLFGLMP 309 A IG AA L + A+ +G +A ++L + ++ + Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 310 MWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGG 369 M +V LA G ML Q E G++ G A +G L Sbjct: 302 MAFPIMVLLASGGIGMPALQ----AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357 Query: 370 LGAMMTPVASASASGFGLLIIGVLLLLVLVELRR 403 + A + + +G+ + L LL L LRR Sbjct: 358 IYA----ASITTWNGWAWIAGAALYLLCLPALRR 387
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 63.0 bits (153), Expect = 2e-13 Identities = 61/285 (21%), Positives = 102/285 (35%), Gaps = 35/285 (12%) Query: 40 HTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQ 99 H P RIV+ LLA+ VAD + R W E L Sbjct: 29 HAAAIDPNRIVALEWLPVELLLALGIVPYG---------VADTINY-RLW---VSEPPLP 75 Query: 100 RLYIG-----EPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKS--- 151 I EP+ E + P ++ SA G S + L+ IAP N+ D Sbjct: 76 DSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPS----PEMLARIAPGRGFNFSDGKQPL 131 Query: 152 --WQSLLTQLGEITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLW 209 + LT++ ++ + A +AQ++ + + K + + ++ Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVF 191 Query: 210 TPESAQGQMLEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQ 269 P S ++L++ G NA Q + + + LAA + + L + Sbjct: 192 GPNSLFQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNS 243 Query: 270 KDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERL 314 KD DA+ A PL +P V+ + + F SAM + L Sbjct: 244 KDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVL 288
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 442 bits (1139), Expect = e-160 Identities = 146/299 (48%), Positives = 195/299 (65%), Gaps = 18/299 (6%) Query: 1 MAIPKLQAYALPDSHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANI 60 MAIP +Q Y +P + D+PQNKV W +P RA LLIHDMQ+YFV + + ++ ANI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 AALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTV 120 L++ C Q IPV YTAQP Q+ +DRALL D WGPGL P ++K++ L P+ DD V Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 180 L KWRYSAF R+ L +M+++ GR+QLIITG+YAHIGC+ TA +AFM DIK F V DA+AD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 FSRDEHLMSLKYVAGRSGRVVMTEELL------PAPIPASKA-----------ALREVIL 223 FS ++H M+L+Y AGR VMT+ LL PA + + A +R+ I Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240 Query: 224 PLLDESDEPFDDD-NLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLS 281 LL E+ E D +L+D GLDSVR+M L +WR+ ++ FV LA+ PTI+ W KLL+ Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 361 bits (928), Expect = e-130 Identities = 109/258 (42%), Positives = 150/258 (58%), Gaps = 20/258 (7%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFD---------------QAFAQEQYPFATE 49 GK ++TGA +GIG A A GA + D +A E +P Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP---- 63 Query: 50 VMDVADAAQVAQVCQRLLAQTERLDVLVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 DV D+A + ++ R+ + +D+LVN AG+LR G LS E+W+ TF+VN G FN Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + +R G+IVTV S+ A PR M+AY +SKAA +GLELA +RC Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N+VSPGST+TDMQ +LW ++ EQ I+G E FK GIPL K+A+P +IA+ +LFL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 230 ASHITLQDIVVDGGSTLG 247 A HIT+ ++ VDGG+TLG Sbjct: 243 AGHITMHNLCVDGGATLG 260
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 28.4 bits (63), Expect = 0.017 Identities = 18/98 (18%), Positives = 39/98 (39%), Gaps = 13/98 (13%) Query: 50 QGITIIKTFDAPGGMKGYLGKYQDMGVTIYLTPDGKHAISG--YMYNEKGENLSNTLIEK 107 + + + F+ YLGK+ ++ + G ++ + N+ G ++ N Sbjct: 21 ESVKPVSDFEL----NNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLN----- 71 Query: 108 EIYAPAGREMWQRMEQSHWLLDGKKDAPVIVYVFADPF 145 Y+ + W+ E + ++G D + V F PF Sbjct: 72 RGYSEE-KGEWKEAEGKAYFVNGSTDGYLKVSFFG-PF 107
>PF03944#delta endotoxin Length = 633 Score = 27.3 bits (60), Expect = 0.009 Identities = 12/43 (27%), Positives = 24/43 (55%), Gaps = 3/43 (6%) Query: 21 IAPLDTQDIDLQINSSVEKQFG---DAIRTTILDVLARYNVRG 60 I+P+ ++ Q + + ++FG D++R + ARY +RG Sbjct: 496 ISPIHATQVNNQTRTFISEKFGNQGDSLRFEQNNTTARYTLRG 538
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 38.6 bits (90), Expect = 1e-05 Identities = 14/67 (20%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Query: 155 NPFTNGHRYLIQQAAAQCDWLHLFLVKEDSSR--FPYEDRLDLVLKGTADIPRLTVHRGS 212 +P T GH +I++ D +++ +++ + + F ++RL+ + K A +P V Sbjct: 10 DPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLPNAQVDSFE 69 Query: 213 EYIISRA 219 ++ A Sbjct: 70 GLTVNYA 76
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.2 bits (151), Expect = 2e-13 Identities = 28/121 (23%), Positives = 51/121 (42%), Gaps = 5/121 (4%) Query: 1 MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARMMIERFKPGLILLDNYL 60 MT T+L+ +D+ + + + + G+ + + N A I L++ D + Sbjct: 1 MTGA-TILVADDDAAIRTVLNQALS-RAGY-DVRITSNAATLWRWIAAGDGDLVVTDVVM 57 Query: 61 PDGRGINLLHELVQAHYPG-DVVFTTAASDMETVSEAVRCGVFDYLIKPIAYERLGQTLT 119 PD +LL + + P V+ +A + T +A G +DYL KP L + Sbjct: 58 PDENAFDLLPRI-KKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Query: 120 R 120 R Sbjct: 117 R 117
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 97.1 bits (242), Expect = 3e-24 Identities = 80/346 (23%), Positives = 140/346 (40%), Gaps = 40/346 (11%) Query: 8 IGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIISMDENNH------ILVGKPAVSRR 61 + IDLGT N+LI V K L PS++++ ++ VG A Sbjct: 13 LSIDLGTANTLIYV-KGQGIVLN--------EPSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 62 TSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSLKEDAEEFLQRPIKDVVISV 121 P AA+ R M +D F ++ ++ + ++ RP V++ V Sbjct: 64 GRTPGNIAAI--RPMKDGVI----ADFFVTEKMLQHFIKQVHSNS---FMRPSPRVLVCV 114 Query: 122 PAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGLHTQQNTRSLVFDLGGGTFDVT 181 P + +R+ R +A+ AG V LI EP AAA+ GL + T S+V D+GGGT +V Sbjct: 115 PVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVA 174 Query: 182 VLEYATPVIEVHASAGDNFLGGEDFTHMLVDEVLKRAAVAKNMLNESELAALYTSVEAAK 241 V+ V + +GG+ F +++ V + ++ E+ + + +A Sbjct: 175 VISLNGVVY-----SSSVRIGGDRFDEAIINYVRRNYGS---LIGEATAERIKHEIGSAY 226 Query: 242 CSNQLPLQISWQYQEET----RECEFYENELEDLWLPLLNRLRVPIEQALRDA--RLKPS 295 ++ +I + + R NE+ + L + + AL L Sbjct: 227 PGDE-VREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASD 285 Query: 296 QID-SLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIVALGAAI 340 + +VL GG + + + R+ + G + DP T VA G Sbjct: 286 ISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGK 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 7e-24 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 1/125 (0%) Query: 2 TNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGI 61 +L+ +D+ AIR L AL G V A DL++ D+ +PD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EFIRDLRQWSA-VPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS 120 + + +++ +PV+V+SA++ I A + GA DYL KPF + EL + AL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 ATTAP 125 + Sbjct: 124 RRPSK 128
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.012 Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 785 LLENAVKYAGAQAE----IGIDAHVEGENLQLDVWDNGPGLPPGQEQT 828 L+EN +K+ AQ I + + + L+V + G +++ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES 310
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 31.4 bits (71), Expect = 0.003 Identities = 11/41 (26%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 14 VDDAPRMQDYTLEAEEGRDM-MLLDALIQLKEKDPSLSFRR 53 +++ + T+E + + MLLDAL+++ + DP L + Sbjct: 339 IENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.020 Identities = 27/196 (13%), Positives = 56/196 (28%), Gaps = 12/196 (6%) Query: 48 EVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSE-EKASTPAQRQQASL 106 E+ + I+ ++ EG +V +L +L + +S +A R Q Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 107 EEQNNDAL----SPAIRRLLAEHNLDASAIKGTGVGGRLTRED----VEKHLAKAPAKES 158 + L P + + T ++ E +L K A+ Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 159 APAAAAPAAQPALAARSEKRVPMTRLRKRVA---ERLLEAKNSTAMLTTFNEVNMKPIMD 215 A + + + L + A +LE +N V + Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277 Query: 216 LRKQYGEAFEKRHGIR 231 + + A E+ + Sbjct: 278 IESEILSAKEEYQLVT 293
>PF03309#Bvg accessory factor Length = 271 Score = 31.7 bits (72), Expect = 0.005 Identities = 10/55 (18%), Positives = 23/55 (41%) Query: 3 IVSVDIGSTWTKAALFAREGDALTLVNHVLTPTTTHHLAKGFFSSLNLVLNVDNA 57 ++++D+ +T T L + GD +V T A +++ ++ D Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDGLIGDDAE 56
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 60.8 bits (147), Expect = 6e-12 Identities = 34/207 (16%), Positives = 71/207 (34%), Gaps = 8/207 (3%) Query: 99 EQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEE 158 E E+ Q QA+ + E A A ++ E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVP----SNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 159 AAK--KAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAA--AAEARKKAATE 214 A+ K + +K E +A + A+ ++ A+ A + +K + E A +E ++ TE Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 215 AAEKAKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKK 274 E A E E+KA E + + K+ + +A ++ + + Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 275 AAAAKAAAAKAAAEKAAAAKAAAEADD 301 + A + A++ ++ + Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVTES 1186 Score = 56.2 bits (135), Expect = 1e-10 Identities = 28/230 (12%), Positives = 74/230 (32%), Gaps = 2/230 (0%) Query: 66 RMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAK 125 R ++E+ + + + Q+ E +E Q E + +EKE A E +K E Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 126 QAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAK--KAAADAKKKAEAEAAKAAAEAQ 183 +++ KQ + + A+ + + E ++ A + E + + Sbjct: 1126 TSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTE 1185 Query: 184 KKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAAEKA 243 ++ + E A + + + K + ++ ++ +++ Sbjct: 1186 STTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRS 1245 Query: 244 AADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAAKAAAEKAAAA 293 +D +A A+ A + A ++ + + Sbjct: 1246 TVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYN 1295 Score = 56.2 bits (135), Expect = 2e-10 Identities = 32/241 (13%), Positives = 87/241 (36%), Gaps = 13/241 (5%) Query: 68 QSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQA 127 Q+ S ++E+ ++ +E ++ + +K E+ A + Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN--EQDATET 1061 Query: 128 ELKQKQ-AEEAAAKAAAD------AKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAA 180 + ++ A+EA + A+ A++ +E E + A + ++KA+ E K Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQE 1121 Query: 181 EAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAA 240 + ++ + ++++E + A AR+ T ++ +++ A E+ A + + Sbjct: 1122 VPKVTSQVSPK--QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV 1179 Query: 241 EKAAADKKAAEK--AAAEKAAADKKAAAEKAAADKKAAAAKAAAAKAAAEKAAAAKAAAE 298 E+ + + E A + + + K ++ + A Sbjct: 1180 EQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATT 1239 Query: 299 A 299 + Sbjct: 1240 S 1240 Score = 55.1 bits (132), Expect = 3e-10 Identities = 33/257 (12%), Positives = 87/257 (33%), Gaps = 21/257 (8%) Query: 51 DAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAE-ELREKQAAEQER------L 103 D V A + ++ ++K+ + + EQ A E + ++ A++ + Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 104 KQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKA 163 + E + ++ ++ Q K+ +K+ KAK E + +E K Sbjct: 1081 QTNEVAQSGSETKETQ-TTETKETATVEKE-----------EKAKVETEKT--QEVPKVT 1126 Query: 164 AADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEA 223 + + K+ ++E + AE ++ + + +++ A E K + E+ E+ Sbjct: 1127 SQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTES 1186 Query: 224 EKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAA 283 + + +E + K + + + ++ + Sbjct: 1187 TTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRST 1246 Query: 284 KAAAEKAAAAKAAAEAD 300 A + + A +D Sbjct: 1247 VALCDLTSTNTNAVLSD 1263
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 47.2 bits (112), Expect = 3e-08 Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 5/146 (3%) Query: 197 AREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALF 256 R Q T + +L + L I +G+ A A IG+ A + + L+L Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGA---GIGVVAAALGYTQWLSLL 148 Query: 257 YFTMVI--YGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQN 314 Y VI GL+ G+++++L + + + P + LSG V PV+ +P+ Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 315 LTWINPIRHFTDITKQIYLKDASLDI 340 P+ H D+ + I L +D+ Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDV 234
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.012 Identities = 20/90 (22%), Positives = 28/90 (31%), Gaps = 21/90 (23%) Query: 293 TPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKELTKKFGDFAATDHVNFAV 352 PR E + +LG P + + + K HV + Sbjct: 547 VPRLEKWLVHVLGKTPDDYKP-------------RRLRYLQLVGKYI----LMGHVARVM 589 Query: 353 KRGEIFG----LLGPNGAGKSTTFKMMCGL 378 + G F L G G GKST + GL Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619 Score = 29.3 bits (65), Expect = 0.047 Identities = 11/23 (47%), Positives = 13/23 (56%) Query: 34 YVTGLVGPDGAGKTTLMRMLAGL 56 Y L G G GK+TL+ L GL Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 62.2 bits (151), Expect = 6e-13 Identities = 42/259 (16%), Positives = 92/259 (35%), Gaps = 25/259 (9%) Query: 82 ALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRT 141 Q + + +A+ +LA E + + + + L + Sbjct: 201 QKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENK 260 Query: 142 ISA--NDLENARSSRDQAQATLKSAQDKLRQYRSGNREQ---DIAQAKASLEQAQAQLAQ 196 N+L +S +Q ++ + SA+++ + + + + Q ++ +LA+ Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAK 320 Query: 197 AELNLQDSTLIAPSDGTLLTRAV-EPGTVLNEGGTVFTVSLT-RPVWVRAYVDERNLDQA 254 E Q S + AP + V G V+ T+ + + V A V +++ Sbjct: 321 NEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFI 380 Query: 255 QPGRKVLLYTDGRPDKPYH---GQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVT--- 308 G+ ++ + P Y G++ ++ A D R LV+ + I + Sbjct: 381 NVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA--------IEDQRLGLVFNVIISIEENC 432 Query: 309 ----DADDALRQGMPVTVQ 323 + + L GM VT + Sbjct: 433 LSTGNKNIPLSSGMAVTAE 451
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.0 bits (176), Expect = 1e-17 Identities = 32/220 (14%), Positives = 74/220 (33%), Gaps = 29/220 (13%) Query: 9 KGEQAKKQLIAAALAQFGEYGMNATT-REIAAQAGQNIAAITYYFGSKEDLYLACAQWIA 67 + ++ ++ ++ AL F + G+++T+ EIA AG AI ++F K DL+ + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 68 DFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSK---FISR 124 IGE E + P + +RE+++ + + + + + Sbjct: 68 SNIGELEL---EYQAKFPGDP---LSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 125 EQLSPTAAYHLVHEQVISPLHSHLTRLIAAW---TGCDASDTRMILHTHALIGEILAFRL 181 E A + + + L I A +I+ I ++ Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM--RGYISGLM---- 175 Query: 182 GKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGLSQR 221 W + + + ++ ++L+ Sbjct: 176 --------ENWLFAPQSFD--LKKEARDYVAILLEMYLLC 205
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.025 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 246 QQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG-NKSQGARTRALADFKSGDIRVLVATDI 304 Q VLV T + + ++ +L K GI+ ++ + A A A + + V +AT++ Sbjct: 450 QPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNM 506 Query: 305 AARGLDI 311 A RG DI Sbjct: 507 AGRGTDI 513
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.010 Identities = 9/18 (50%), Positives = 12/18 (66%) Query: 31 LVLLGPSGAGKSSLLRVL 48 +VL G G GKS+L+ L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 30.7 bits (69), Expect = 0.007 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 9/54 (16%) Query: 2 RRVFWLVAAALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRIKVMVIHYTADD 55 R+V LV ALL AG A I K+G +LD Y ++ + HY +DD Sbjct: 3 RKVLALVIPALLAAGAAHAAEIYNKDGNKLDL-------YGKVDGL--HYFSDD 47
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 75.2 bits (185), Expect = 2e-17 Identities = 70/363 (19%), Positives = 123/363 (33%), Gaps = 65/363 (17%) Query: 13 MKVLVTGATSGLGRNAVEFLCQKGISVRA---------TGRNEAMGKLLEKMGAEFVPAD 63 MK LVTGA +G + + L + G V +A +LL + G +F D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 64 LTELVSSQAKVMLAGIDTLWHCS-------SFTSPWGTQQAFDLANVRATRRLGEWAVAW 116 L + + ++ S +P A+ +N+ + E Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPH----AYADSNLTGFLNILEGCRHN 116 Query: 117 GVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQTRFT 176 +++ ++ SS S+Y + D + +A +K A+E + + S T Sbjct: 117 KIQHLLYASSSSVYGL-NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH-LYGLPAT 174 Query: 177 ILRPQSLFGPHDK--VFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEA 234 LR +++GP + + + + M SI + + G D TY ++ A+ Sbjct: 175 GLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 235 CDKLPS--------------GRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLD 280 RVYNI N L +Q L D L I+ + +P D Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGD 294 Query: 281 MIARSMERLGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVLTLDEGIEKTAAW 340 + T D E +G+ P T+ +G++ W Sbjct: 295 V----------------LETS-----------ADTKALYEVIGFTPETTVKDGVKNFVNW 327 Query: 341 LRD 343 RD Sbjct: 328 YRD 330
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 722 bits (1865), Expect = 0.0 Identities = 244/843 (28%), Positives = 392/843 (46%), Gaps = 35/843 (4%) Query: 2 LRMTPLASAI---VALLLGIEAYAAEETFDTHFMIGGMKDQQVANIRL--DDNQPLPGQY 56 R+ + A +AE F+ F+ Q VA++ + + PG Y Sbjct: 21 HRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADD--PQAVADLSRFENGQELPPGTY 78 Query: 57 DIDIYVNKQWRGKYEIIVKDNPQET----CLSREIIKRLGINTD-----NFASGKQCLTF 107 +DIY+N + ++ E CL+R + +G+NT N + C+ Sbjct: 79 RVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPL 138 Query: 108 EQLVQGGSYTWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYVSQYYSDY 167 ++ + D+G RL+ ++PQA++ GY+PPE W+ GINA +Y S Sbjct: 139 TSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQN 198 Query: 168 KASGNSKSTYVRFNSGLNLLGWQLHSDASFSKTNSNPGV-----WKSNTLYLERGFAQLL 222 + GNS Y+ SGLN+ W+L + ++S +S+ W+ +LER L Sbjct: 199 RIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLR 258 Query: 223 GTLRVGDMYTSSDIFDSVRFSGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVTIEQNGF 282 L +GD YT DIFD + F G +L D MLP+S++ F P + GIA+ A VTI+QNG+ Sbjct: 259 SRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGY 318 Query: 283 VVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQPGVSKYDF 342 +Y VPPGPF I D+ AG DL V++KEADGS + VPY++VP + + G ++Y Sbjct: 319 DIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSI 378 Query: 343 AAGRSHIEGASKQSD-FVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGTGWNT-RIGAIS 400 AG A ++ F Q+ +G T+YGG+ +A+ Y AF G G N +GA+S Sbjct: 379 TAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALS 438 Query: 401 VDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRTFNDHVWANNK 460 VD T+++S + DGQS + YNK ++++ T L +RYS+ Y F D ++ Sbjct: 439 VDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMN 498 Query: 461 DNYRRDENDIYDI----ADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLWRDYWGRSG 516 ++ + + DYY + ++ ++Q L ++ LS + YWG S Sbjct: 499 GYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSN 557 Query: 517 SSKDYQLSYSNNLRRISYTLAASHAYDENHHE-EKRFNIFISIPFD--WGDDVTTPRRQI 573 + +Q + I++TL+ S + ++ + ++IPF D + R Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 574 YMSNSTTFDDQGVASNNTGLSGTVGSRDQFNYGVNLSYQYQGN---ETTAGANLTWNAPV 630 S S + D G +N G+ GT+ + +Y V Y G+ +T A L + Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 631 ATVNGSYSQSSAYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDAYVNGQKYR 690 N YS S +Q VSGG++A + GV L L++T ++ APG KDA V Q Sbjct: 678 GNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 691 TTNRNGVVVYDGMTPYRENYLMLDVSQSDSEAELRGNRKIAAPYRGAVVLVNFDTDQRKP 750 T+ G V T YREN + LD + +L P RGA+V F + Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA-RVGI 796 Query: 751 WFIKALRADGQPLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVNVAIDKQQGLSCT 810 + L + +PL FG V + G+V Q+++ + V V +++ C Sbjct: 797 KLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 811 ITF 813 + Sbjct: 857 ANY 859
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 27.9 bits (62), Expect = 0.007 Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 6 KMLLGALLLVTSAAWAAPATAGSTNTSGISKYE-LSSFIADF 46 ++L G LLL++S +WA ++K E L + DF Sbjct: 11 RVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDF 52
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 31.9 bits (72), Expect = 0.003 Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 2/92 (2%) Query: 156 AQGCENKNVIIIGAGT-IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSRE 214 A+G E K I GA IG + + GA + A+D + EKL S + ++ Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 215 MSAPQIQGVLRELRFNQLILETAGVPQTVELA 246 A + ++ E + V +A Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVA 93
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 6e-18 Identities = 28/136 (20%), Positives = 65/136 (47%), Gaps = 1/136 (0%) Query: 11 PRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGL 70 IL+ +D+ + +L L A Y + S+ + ++ DL++ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 TLCREIR-RFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCK 129 L I+ D+P+++++A+ + + E GA DY+ KP+ E++ + L K Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 130 PQRELQQQDAESPLII 145 + + D++ + + Sbjct: 124 RRPSKLEDDSQDGMPL 139
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 33.6 bits (77), Expect = 0.002 Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 20/95 (21%) Query: 164 RQTSWLIVALSTLLAALATF------PLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSE 217 RQ + L+ A L AL P L+A V+ V H LA + P S Sbjct: 75 RQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD---AMKCFPGSF 131 Query: 218 DEL-----------GKLAQDFNQLASTLEKNQQMR 241 + L G L N+LA E+ QQMR Sbjct: 132 ERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMR 166
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 125 bits (315), Expect = 1e-33 Identities = 97/429 (22%), Positives = 188/429 (43%), Gaps = 23/429 (5%) Query: 20 FMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFF 79 F L+ ++N +LP +A + P + V +++LT ++ G L+D++G++ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 80 TAIVLFTLGSLFCALSGTLNELL-LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTF 138 I++ GS+ + + LL +AR +QG G A + + V + +P+E A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 139 VTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLM-LMPNYTMQTRRFDL 197 + +G +GPA+GG++ Y HW +L+ IP+ I + LM L+ FD+ Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 198 SGFLLLAVGMAVLTLALDGSKGTGLSPLAIAGLVAVGVVALVLYLLHARNNNRALFSLKL 257 G +L++VG+ L + + V V++ ++++ H R L Sbjct: 202 KGIILMSVGIVFFMLF---------TTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 258 FRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG-LMMIPMVLGSMGMKRI 316 + F +G+ M P ++ S G +++ P + + I Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 317 VVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALL----GWYYVLPFVLFLQGMVNSTRFS 372 +V+R G VL +G++ +++ F+T + L W+ + V L G+ S + Sbjct: 313 GGILVDRRGPLYVL---NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL--SFTKT 367 Query: 373 SMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVF 432 ++T+ L A +G SLL+ LS G+ I G LL + + Q+ + Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTY 427 Query: 433 MYTWLSMAF 441 +Y+ L + F Sbjct: 428 LYSNLLLLF 436
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 918 bits (2373), Expect = 0.0 Identities = 287/1035 (27%), Positives = 505/1035 (48%), Gaps = 36/1035 (3%) Query: 6 LFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVAT 65 FI RP+ +L++ + + G L LPVA P + P + VSA+ PGA +T+ +V Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLERSLGRIAGVSEMTSSS-SLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMP 124 +E+++ I + M+S+S S GS I L F D + A VQ + A LLP + Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 125 SRPTYRKANPSDAPIMILTLTSDT--YSQGELYDFASTQLAPTISQIDGVGDVDVGGSSL 182 + S + +M+ SD +Q ++ D+ ++ + T+S+++GVGDV + G+ Sbjct: 124 -QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 183 PAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQG------VLEDGTHRWQIQTNDELK 236 A+R+ L+ L ++ DV + N + G L I K Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 237 TAAEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQ 295 E+ + + N +G VRL DVA V ++ N KPA L I+ AN + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 296 TVDSIRARLPELQSTIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRS 355 T +I+A+L ELQ P + + D +P ++ S+ EV +TL ++ LV LV++LFL++ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 356 GRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHL- 414 RAT+IP +AVPV L+GTFA + G+S+N L++ + +A G +VDDAIVV+EN+ R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGIS 474 E + P +A + ++ ++ +++ L AVF+P+ GG G + R+F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 475 LLVSLTLTPMMCGWMLKASKPREQKRLRGFG----RMLVALQQGYGKSLKWVLNHTRLVG 530 +LV+L LTP +C +LK + GF Y S+ +L T Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 531 VVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQ----AMRGKLQDFMKII 586 ++ +A + L++ +P +F PE+D GV + IQ + + + ++K Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 587 RD-DPAVDNVTGFT-GGSRVNSGMMFITLKPRGERS---ETAQQIIDRLRVKLAKEPGAN 641 + +V V GF+ G N+GM F++LKP ER+ +A+ +I R +++L K Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 642 LFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATL-----PELADVNSD 696 + + I G + ++ L D + + R +L + L V + Sbjct: 662 VIPFNMPAIVELGTATGFDFE---LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 697 QQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRY 756 ++ A+ L D++ LG+ + N ++ A G ++ K+ ++ D ++ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 757 TQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSD 816 ++K++V + G+ +P S F + + I G S D Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 817 ASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVH 876 A A ++ ++L P+ + + G + + + N L+ + V++ L LYES+ Sbjct: 839 AMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 877 PLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGN 936 P++++ +P VG LLA LFN + ++G++ IG+ KNAI++V+FA + Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 937 LTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLL 996 EA A +R RPI+MT+LA + G LPL +S G GS + +GI ++GG+V + LL Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 997 TLYTTPVVYLFFDRL 1011 ++ PV ++ R Sbjct: 1017 AIFFVPVFFVVIRRC 1031 Score = 80.7 bits (199), Expect = 2e-17 Identities = 77/446 (17%), Positives = 162/446 (36%), Gaps = 26/446 (5%) Query: 592 VDNVTGFTGGS-RVNSGMMFITLKPRGERSETAQQIIDRLRVKLAKEPGANLFLMAVQDI 650 +DN+ + S S + +T + + Q+ ++L++ P + Q I Sbjct: 72 IDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE----VQQQGI 127 Query: 651 RVGGRQSNASYQYTLLSDDLAALREW-----EPKIRKKLATLPELADVNSDQQDNGAE-- 703 V S+ +SD+ ++ ++ L+ L + DV GA+ Sbjct: 128 SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL----FGAQYA 183 Query: 704 MNLVYDRDTMARLGID----VQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQD 759 M + D D + + + + + + T P Q + R+ Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 760 ISALEKMFVINNEGKAIPLSYFAK--WQPANAPLSVNHQGLSAASTISFNLPTGKSLSDA 817 + +N++G + L A+ N + G AA +L D Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL-DT 302 Query: 818 SAAIDRAMTQL--GVPSTVRGSFA-GTAQVFQETMNSQVILIIAAIATVYIVLGILYESY 874 + AI + +L P ++ + T Q +++ V + AI V++V+ + ++ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 875 VHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRH 934 L +P +G L F + + + G++L IG++ +AI++V+ Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 935 GNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQ 994 L P+EA ++ ++ + +P+ GG + + ITIV + +S Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 995 LLTLYTTPVVYLFFDRLRLRFSRKPK 1020 L+ L TP + + + K Sbjct: 483 LVALILTPALCATLLKPVSAEHHENK 508
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 104 bits (262), Expect = 1e-27 Identities = 76/353 (21%), Positives = 122/353 (34%), Gaps = 42/353 (11%) Query: 6 LITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPH--------TCNPK 57 L+TG G G ++++ LLE G++V GI + N Y D P Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGI----DNLND------YYDVSLKQARLELLAQPG 53 Query: 58 FHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAI 117 F H DL+D +T + + V+ V S E+P AD + G L +LE Sbjct: 54 FQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGC 113 Query: 118 RFLGLEKKTRFYQASTSELYGLVQEIPQKETTPF-YPRSPYAVAKLYAYWITVNYRESYG 176 R ++ AS+S +YGL +++P +P S YA K + Y YG Sbjct: 114 RHNKIQ---HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 177 MYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKM 236 + A F P K T+A+ G +Y RD+ + D + Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFTKAMLE---GKSIDVY-NYGKMKRDFTYIDDIAEA 226 Query: 237 QWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAP 296 + D +G + E + DA Sbjct: 227 IIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIG------NSSPVELMDYIQAL-EDAL 279 Query: 297 GVKPGDVIIAVDPRY--FRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMV 347 G++ +P +V D +E +G+ PE T+++ V V Sbjct: 280 GIE-------AKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFV 325
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 87.1 bits (216), Expect = 1e-21 Identities = 66/344 (19%), Positives = 132/344 (38%), Gaps = 47/344 (13%) Query: 5 RIFIAGHRGMVGSAIRRQLEQRG-------------DVEL------VLRTRD----ELNL 41 + + G G +G + ++L + G DV L +L +++L Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 42 LDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNK 101 D + D FAS ++V+++ + + + P + N+ NI+ N + Sbjct: 62 ADREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 102 LLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSV 161 LL+ SS +Y K P + P + YA K A + +Y+ YG + Sbjct: 121 LLYASSSSVYGLNRKMPFSTD---DSVDHPVS-LYAATKKANELMAHTYSHLYGLPATGL 176 Query: 162 MPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAAS 221 +YGP P L +F +A + + V+ G R+F ++DD+A A Sbjct: 177 RFFTVYGPWGR--PD------MALFKFTKAMLEGKS-IDVYNYGKMKRDFTYIDDIAEAI 227 Query: 222 IHVMELAH----EVWLENTQPMLSH-----INVGTGVDCTIRELAQTIAKVVGYKGRVVF 272 I + ++ + +E P S N+G + + Q + +G + + Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNM 287 Query: 273 DASKPDGTPRKLLDVTRLHQ-LGWYHEISLEAGLASTYQWFLEN 315 +P D L++ +G+ E +++ G+ + W+ + Sbjct: 288 LPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 93.7 bits (233), Expect = 5e-24 Identities = 70/334 (20%), Positives = 126/334 (37%), Gaps = 62/334 (18%) Query: 4 NVLLIGASGFVGT----RLLE----------------TAIADFNIKNLDKQQSHFYPEIT 43 L+ GA+GF+G RLLE ++ ++ L + F+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHK--- 58 Query: 44 QIGDVRDQQALDQALA--GFDTVVLLAAEH--RDDVSPTSLYYDVNVQGTRNVLAAMEKN 99 D+ D++ + A F+ V + R + Y D N+ G N+L N Sbjct: 59 --IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN 116 Query: 100 GVKNIIFTSSVAVYGLNKHNP-DENHPHD-PFNHYGKSKWQAEEVLREWYNKA---PTER 154 ++++++ SS +VYGLN+ P + D P + Y +K +A E++ Y+ P Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATK-KANELMAHTYSHLYGLPA-- 173 Query: 155 SLTIIRPTVIFGERNRGN--VYNLLKQIAGGKFMMV-GAGTNYKSMAYVGNIVEFIKYKL 211 T +R ++G R + ++ K + GK + V G + Y+ +I E I Sbjct: 174 --TGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQ 231 Query: 212 KNVA-----------------AGYEVYNYVDKPDLNMNQLVAEVEQSLNKKIPSMHLPYP 254 + A Y VYN + + + + +E +L + LP Sbjct: 232 DVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQ 291 Query: 255 LGMLGGYCFDI--LSKITGKKYAVS-SVRVKKFC 285 G + D L ++ G + VK F Sbjct: 292 PGDVLETSADTKALYEVIGFTPETTVKDGVKNFV 325
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 28.6 bits (64), Expect = 0.042 Identities = 27/165 (16%), Positives = 56/165 (33%), Gaps = 23/165 (13%) Query: 42 VLMDYTTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVGRDAWAKDN 101 + MD +G+ LTA ++ S K++ V +D+ + + + + Sbjct: 43 IEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYS 102 Query: 102 PV---FVGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYA 158 PV + + +V +L I S N A L + G + + Sbjct: 103 PVSEKHLADGM---------TVGELCAAAITMSDNSAANLLLATVGG-----PAGLTAFL 148 Query: 159 EKLHLKDTH---FETVHGLDAPGQH---SSAYDLAVLSRAIIHGE 197 ++ T +ET PG ++ +A R ++ + Sbjct: 149 RQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQ 193
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 27.5 bits (61), Expect = 0.012 Identities = 13/83 (15%), Positives = 33/83 (39%), Gaps = 6/83 (7%) Query: 16 RLFRRKNKLQREIQDVEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKGDYEDR 75 +++ NKL++ + +++ N++ + L ++ I + + I+ I E Sbjct: 385 SYYKKYNKLKKSEEAANEQLLQNEEELNYLYSVLTNINNADNYDEIEEIKK------ELI 438 Query: 76 VDDYIIKNAELSKERRDISKKLK 98 YI ++ SK + Sbjct: 439 ETGYIKFKKIYKSKKSKTSKPMH 461
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.0 bits (104), Expect = 7e-07 Identities = 63/383 (16%), Positives = 114/383 (29%), Gaps = 34/383 (8%) Query: 51 AEMGYVFSAFAWLYTLCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGL 110 A G + + +A + C G DR G R +++ G +V A L L Sbjct: 43 AHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIG 102 Query: 111 RAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWH 170 R + GI A + ERA GF ++ G+ P+L + S H Sbjct: 103 RIVAGITGAT-GAVAGAYIADITDGDERARHFGFMSACFGFGMV-AGPVLGGLMGGFSPH 160 Query: 171 WVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLT 230 F + + L + + P+++EA PL Sbjct: 161 APFFAAAALNGLNFLTGCFLLPESHKGER-------------------RPLRREALNPLA 201 Query: 231 AKDWKLVFHRKLIGVYLGQFAVTSTLWFFLTWFPNYLTQEKGITALKAGFMTSVPFLAAF 290 + W + + F + + + A G + Sbjct: 202 SFRWARGM-TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAA---FGI 257 Query: 291 VGVLLSGWVADLLVRKGFSLGFARKTPIICGLLISTC--IMGANYTNDPMMIMCLMALAF 348 + L + + + + ++ G++ I+ A T M ++ LA Sbjct: 258 LHSLAQAMITGPVAAR-----LGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLAS 312 Query: 349 FGNGFASITWSLVSSLAPMRLIGLTGGVFNFVGGLGGITVPLVVGYL-AQGYGFAPALVY 407 G G ++ +++S G G + L I PL+ + A + Sbjct: 313 GGIGMPALQ-AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAW 371 Query: 408 ISAVALIGALSYILMVGDVKRVG 430 I+ AL L G G Sbjct: 372 IAGAALYLLCLPALRRGLWSGAG 394
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 37.6 bits (87), Expect = 9e-05 Identities = 73/369 (19%), Positives = 132/369 (35%), Gaps = 57/369 (15%) Query: 89 IGALLFGWIGDKHGRKIVMVITIGLMGMSTMLIGLIPSYAQIGVWAPICLVILRFSQGLG 148 IG ++G + D+ G K +++ I + +++ + S+ + L++ RF QG G Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL-------LIMARFIQGAG 116 Query: 149 AGAELSGGTVMLGEYAPVKRR----GLVSSVIGLGSNSGTLLASLVWLIVLQMDKDDLLS 204 A A + V++ Y P + R GL+ S++ +G G + ++ + Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMI---------AHYIH 167 Query: 205 WGW--RIPFLCSILIAAAALLIRRHIRETPVFERQKALLQ--AEREKVIREEKAQQQHDS 260 W + IP + I + L+++ +R F+ + +L ++ Sbjct: 168 WSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLI 227 Query: 261 RS------FWKRTRAFWT-MVGLRIGENGP--SYLAQGFII--GYVAKVLMVDKSVPTAA 309 S F K R V +G+N P + G II V MV + Sbjct: 228 VSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVH 287 Query: 310 VLIASVLGFAII-----------PLAGWLSDRFGRRIIYRWFCLLLILYAFPAFMLLDSR 358 L + +G II + G L DR G + L + A LL++ Sbjct: 288 QLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETT 347 Query: 359 EPWIVIPTIITGMGLA----SLGIFGVQAAWGVELFGVTNRYTKMAFAKELGSILSGGTA 414 ++ I + GL+ + + E + +F LS GT Sbjct: 348 SWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSF-------LSEGTG 400 Query: 415 PLIASALLS 423 I LLS Sbjct: 401 IAIVGGLLS 409
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 28.2 bits (63), Expect = 0.043 Identities = 18/84 (21%), Positives = 33/84 (39%), Gaps = 15/84 (17%) Query: 193 REMLNTQDRIRGWQQALEASSLVVNPSWIFSTNYTRAGGYEATKRMLEHQLPRALFATNE 252 +E+ + R + +S +V NP T+ Y+ E LP F + Sbjct: 243 QEIQSRNMR----ENVKRSSVVVANP-----THIAIGILYKRG----ETPLPLVTFKYTD 289 Query: 253 QQALGCLRALA-EHGLRVPEDVAL 275 Q +R +A E G+ + + + L Sbjct: 290 AQVQT-VRKIAEEEGVPILQRIPL 312
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 27.8 bits (61), Expect = 0.006 Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 12/80 (15%) Query: 8 LTTVLFSMSASAALTPACEEYYKEIDNFVAKMKEMG-TPEAQVNTLKQQYEQSRKQIAAL 66 L VL ++S P E Y F+ ++ E T Q+NTL+QQ E ++ Q++ L Sbjct: 572 LLEVLVTLSQQG--QPVSSETY----GFLNRLTEAKITLSQQLNTLQQQQESAKAQLSIL 625 Query: 67 PDASQDMACKQGLDALRQSM 86 + S A D RQS+ Sbjct: 626 INRSGSWA-----DVARQSL 640
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.6 bits (178), Expect = 7e-17 Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 4/116 (3%) Query: 4 VLIVDDDILVADVIRRIVEQTPAFKCCGIALSLGQAKEIISVNKKLADLILLDLYINKDN 63 +L+ DDD + V+ + + + + + + I+ DL++ D+ + +N Sbjct: 6 ILVADDDAAIRTVLNQALSRA-GYDVRITS-NAATLWRWIA--AGDGDLVVTDVVMPDEN 61 Query: 64 GLDLLPFLHSIHCKSDVIVISAADDSATIKDSLHYGVSDYLIKPFHISRLVDSLTR 119 DLLP + V+V+SA + T + G DYL KPF ++ L+ + R Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 35.2 bits (81), Expect = 4e-04 Identities = 39/259 (15%), Positives = 96/259 (37%), Gaps = 18/259 (6%) Query: 79 LGGVIFGHFGDRLGRKRMLMLTVWMMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFA 138 +G ++G D+LG KR+L+ + + + + + SF ++ I+ ++ A Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL----LIMARFIQGAGAAA 119 Query: 139 VGGEWGGAALLSVESAPKNKK-AFYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWG 197 + + K S V +G GVG + + I Sbjct: 120 FPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------------H 167 Query: 198 WRIPFLFSIVLVLGALWVRNGMEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLKIIA 257 W L ++ ++ ++ +++ + + + ++ +L + + Sbjct: 168 WSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLI 227 Query: 258 LRLCELLTMYIVTAFALNYSTQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRR 317 + + L +++ + + GL + + IG+L GG+ T+ F + + Sbjct: 228 VSVLSFL-IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDV 286 Query: 318 VYITGALIGTLSAFPFFMA 336 ++ A IG++ FP M+ Sbjct: 287 HQLSTAEIGSVIIFPGTMS 305
>INTIMIN#Intimin signature. Length = 939 Score = 697 bits (1799), Expect = 0.0 Identities = 218/790 (27%), Positives = 347/790 (43%), Gaps = 70/790 (8%) Query: 139 QQIASTSQPIGSLLAEDMNSEQAANMARGWASSQASGAMTDWLSRFGTARITLGVDEDFS 198 QQ AS + S +N + A + A G A +QAS + WL +GTA + L +F Sbjct: 168 QQAASLGSQLQS---RSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD 224 Query: 199 LKNSQFDFLHPWYETPDNLFFSQHTLHRTDERTQINNGLGWRHFTPTWMSGINFFFDHDL 258 S DFL P+Y++ L F Q D R N G G R F P M G N F D D Sbjct: 225 --GSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDF 282 Query: 259 SRYHSRAGIGAEYWRDYLKLSSNGYLPLTNWRSAPELDNDYEARPANGWDVRAEGWLPAW 318 S ++R GIG EYWRDY K S NGY ++ W + DY+ RPANG+D+R G+LP++ Sbjct: 283 SGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYN-KKDYDERPANGFDIRFNGYLPSY 341 Query: 319 PHLGGKLVYEQYYGDEVALFDKDDRQSNPHTITAGLNYTPFPLMTFSAEQRQGKQGENDT 378 P LG KL+YEQYYGD VALF+ D QSNP T G+NYTP PL+T + R G END Sbjct: 342 PALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDL 401 Query: 379 RFAVDFTWQPGSAMQKQLDPNEVAARRSLAGSRYDLVDRNNNIVLEYRKKELVRLTLTDP 438 +++ F +Q +Q++P V R+L+GSRYDLV RNNNI+LEY+K++++ L + Sbjct: 402 LYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHD 461 Query: 439 VTGKSGEVKSLVSSLQTKYALKGYNVEATALEAAGGKVVTTG----KDILVTLPAYRFTS 494 + G + + +++KY L + +AL + GG++ +G +D LPAY Sbjct: 462 INGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAY---- 517 Query: 495 TPETDNTWPIEVTAEDVKGNLSNREQ-SMVVVQAPTLSQKDSSVSLSTQTLSADSHSTAT 553 N + + A D GN SN ++ V+ + + + SA + T Sbjct: 518 VQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEA 577 Query: 554 LTFIAH------DAAGNPVIGLVLSTRHEGVQDITLSEWKDNGDGSYTQILTTGAMSGTL 607 +T+ A A PV ++S G ++ + NG G T L + + Sbjct: 578 ITYTATVKKNGVAQANVPVSFNIVS----GTAVLSANSANTNGSGKATVTLKSDKPGQVV 633 Query: 608 TLMPQLNGVDAAKAPAVVNIISISSSRTHSSIKIDKDRYLSGNPIEVTVELR-DENDKPV 666 A A AV I + + + IK DK ++ +T ++ + DKPV Sbjct: 634 VSAKTAEMTSALNANAV--IFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPV 691 Query: 667 KEQKQQLNNAVSIDNVKPGVTTDWKETADGVYKATYTAYTKGSGL-TAKLLMQNWNEDLH 725 Q+ + K +T+ K +G K T T+ T G L +A++ + Sbjct: 692 SNQEVTFTTTLG----KLSNSTE-KTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAP 746 Query: 726 TAGFIIDANPQSAKIATLSASNNGVLANENAANTVSVNVADEGSNPINDHTVTFAVLSGS 785 F I + G L + + ++ Sbjct: 747 EVEFFTTLTIDDGNIEIVGTGVKGKLPTV---------------------WLQYGQVNLK 785 Query: 786 ATSFNNQNTAKTDVNGLATFDLKSSK---QEDNTVEVTLENGVKQTLIVSFVGDSSTAQV 842 A+ N + T ++ +A+ D S + +E T +++ + QT ++ + + + Sbjct: 786 ASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQT--ATYTIATPNSLI 843 Query: 843 ELQKSKNEVVADGNDSATMTATVRDAKGNLLNDVKVTF----------NVNSAEAKLSQT 892 SK D ++ + N L +V + + + + + QT Sbjct: 844 VPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAANKYEYYKSSQTIISWVQQT 903 Query: 893 EVNSHDGIAT 902 ++ G+A+ Sbjct: 904 AQDAKSGVAS 913 Score = 196 bits (498), Expect = 9e-53 Identities = 95/376 (25%), Positives = 157/376 (41%), Gaps = 34/376 (9%) Query: 821 LENGVKQTLIVSFVGDSSTAQ--VELQKSKNEVVADGNDSATMTATVRDAKGNLLNDVKV 878 N V T+ V G + K ADG ++ T TATV+ N V V Sbjct: 538 SSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQAN-VPV 596 Query: 879 TFNVNSAEAKLSQTEVNSH-DGIATATLTSLKNGDYRVTASVSSGSQA-NQQVIFIGDQS 936 +FN+ S A LS N++ G AT TL S K G V+A + + A N + DQ+ Sbjct: 597 SFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQT 656 Query: 937 TAALTLSVPSGDITVTNTAPLHMTATLQ-DKNGNPLKDKEITFSVPNDVASRFSISNSGK 995 A++T + + T +T T++ K P+ ++E+TF+ + ++ Sbjct: 657 KASIT-EIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFT------TTLGKLSNST 709 Query: 996 GMTDSNGTAIASLTGTLAGTHMITARLANSNVSDTQPMTFVADKDRAVVVLQTSKAEIIG 1055 TD+NG A +LT T G +++AR+++ V P + + + EI+G Sbjct: 710 EKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEV----EFFTTLTIDDGNIEIVG 765 Query: 1056 NGVDETTLTATVK-DPSNHPVAGITVNFTMPQGVAANFTLENNGIAITQANGEAHVTLKG 1114 GV T ++ N +G +T + N IA A+ VTLK Sbjct: 766 TGVKGKLPTVWLQYGQVNLKASGGNGKYT--------WRSANPAIASVDAS-SGQVTLKE 816 Query: 1115 KKAGTHTVTATLGNNNTSDSQPVTFVADKTSAQVVLQMSKDEITGNGVDNATLTATVKDQ 1174 K GT T++ +SD+Q T+ ++ +V MSK + V+ Sbjct: 817 K--GTTTISVI-----SSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPS 869 Query: 1175 FDNEVNNLPVTFSSAS 1190 NE+ N+ + +A+ Sbjct: 870 SQNELENVFKAWGAAN 885 Score = 88.6 bits (219), Expect = 2e-19 Identities = 92/395 (23%), Positives = 132/395 (33%), Gaps = 49/395 (12%) Query: 1117 AGTHTVTATLGNNNTSDSQPVTFVADKTSAQVVLQMS--------KDEITGNGVDNATLT 1168 + + VTA + N + S V S V+ K +G + T T Sbjct: 522 SNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYT 581 Query: 1169 ATVKDQFDNEVNNLPVTFSSASSGLTLTPGVSNTNESGIAQATLAGVAFGEQTVTASLAN 1228 ATVK + N PV+F+ S L+ +NTN SG A TL G+ V+A A Sbjct: 582 ATVKKNGVAQANV-PVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAE 640 Query: 1229 NGASDNKTVHFIGDTAAAKIIELTPVPDSIIAGTPQNSSGSVITATV-VDNNGFPVKGVT 1287 ++ N D A I E+ + +A IT TV V PV Sbjct: 641 MTSALNANAVIFVDQTKASITEIKADKTTAVANGQ-----DAITYTVKVMKGDKPVSNQE 695 Query: 1288 VNFTSRTNSAEMTNGGQAVTNEQGKATVTYTNTRSSIESGARPDTVEASLENGSSTLSTS 1347 V F T + + T+ G A VT T+T G S +S Sbjct: 696 VTF---TTTLGKLSNSTEKTDTNGYAKVTLTSTTP-----------------GKSLVSAR 735 Query: 1348 INVNADASTAHLTLLQALFDTVSAGDTTNLYIEVKDNYGNGVPQQ--EVTLRVSPSEGVT 1405 + +D + F T++ D N+ I G GV + V L+ Sbjct: 736 V---SDVAVDVKAPEVEFFTTLTI-DDGNIEIV-----GTGVKGKLPTVWLQYGQVNLKA 786 Query: 1406 PSNNAIYTTNHDGNFYASFTATKAGV---YQVTATLENGDSMQQTVTYVPNVANAEITLA 1462 N YT AS A+ V + T T+ S QT TY N+ I Sbjct: 787 SGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIVPN 846 Query: 1463 ASKDPLIADNNDLTTLTATVADTEGNAIANTEVTF 1497 SK D + + N + N + Sbjct: 847 MSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAW 881 Score = 82.8 bits (204), Expect = 1e-17 Identities = 92/467 (19%), Positives = 170/467 (36%), Gaps = 40/467 (8%) Query: 1908 SGGKVRTNSSGQA--------PVVLTSNKVGTYTVTASFHNGVT----IQTQTTVKVTGN 1955 GG+++ + S A V + V T A NG + + T T + Sbjct: 495 QGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQV 554 Query: 1956 SSTAHVASFIADPSTIAATNSDLSTLKATVEDGSGNLIEGLTVYFALKSGSATLTSLTAV 2015 V F AD ++ A ++ T ATV+ +G + V F + SG+A L++ +A Sbjct: 555 VDQVGVTDFTADKTSAKADGTEAITYTATVKK-NGVAQANVPVSFNIVSGTAVLSANSAN 613 Query: 2016 TDQNGIATTSVKGAMTGSVTVSAVTTAGGMQTVDITLVAGPADTSQSVLKSNRSSLKGDY 2075 T+ +G AT ++K G V VSA TA ++ V T S+ + Sbjct: 614 TNGSGKATVTLKSDKPGQVVVSA-KTAEMTSALNANAVIFVDQTKASITEIKADKTTAVA 672 Query: 2076 TDSAELRLVLHDISGNPIKVSEGMEFVQSGTNVPYIKISAIDYSLNINGDYKATVTSGGE 2135 + + + G+ ++ + F + + + NG K T+TS Sbjct: 673 NGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKT-----DTNGYAKVTLTSTTP 727 Query: 2136 GIATLIPVLNGVHQAGLSTTIQFTRAEDKIMSGTVSVNGTDLPTTTFPSQGFTGAYYQLN 2195 G + + ++ V + ++F I G + + GT + P+ L Sbjct: 728 GKSLVSARVSDVAVDVKAPEVEF-FTTLTIDDGNIEIVGTGV-KGKLPTVWLQYGQVNLK 785 Query: 2196 NDNFAPGKTAADYEFSSSASWVDVDATGKVTFKNVGSNWERITATPKSGGPSYVYEIRVK 2255 + G + ++ A ++G+VT K G+ I+ + Y I Sbjct: 786 ---ASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTT--TISVISSDNQTA-TYTIATP 839 Query: 2256 SWWVNAGEAF-MIYSLAENFCSSNGYTLPRANYLNHSSSRGIGSLYSEWGDMGHYTTDAG 2314 + + + + Y+ A N C + G LP SS + +++ WG Y Sbjct: 840 NSLIVPNMSKRVTYNDAVNTCKNFGGKLP-------SSQNELENVFKAWGAANKYEYYKS 892 Query: 2315 FQSNMYW-----SSSPANSSEQYVVSLATGDQSVFEKLGFAYATCYK 2356 Q+ + W + + + Y + ++ AYATC K Sbjct: 893 SQTIISWVQQTAQDAKSGVASTYDLVKQNPLNNIKASESNAYATCVK 939 Score = 67.8 bits (165), Expect = 4e-13 Identities = 55/264 (20%), Positives = 85/264 (32%), Gaps = 18/264 (6%) Query: 1387 NGVPQQEVTLRVSPSEGVTPSNNAIYTTNHDGNFYASFTATKAGVYQVTATLENGDSMQQ 1446 NGV Q V + + G + TN G + + K G V+A S Sbjct: 587 NGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALN 646 Query: 1447 T--VTYVPNVANAEITLAASKDPLIADNNDLTTLTATVADTEGNAIANTEVTFTLPEDVK 1504 V +V + + A K +A+ D T T V ++N EVTFT Sbjct: 647 ANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKV-MKGDKPVSNQEVTFT------ 699 Query: 1505 ANFTLSDGGKAITDAEGKAKVTLKGTKAGAHTVTASMTGGKSE--QLVVNFIADTLSAQV 1562 TD G AKVTL T G V+A ++ + V F Sbjct: 700 TTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDG 759 Query: 1563 NLNVTEDNFIANNVGMTTLQATVTDGNGN-PLANEAVTFTLPADVSASFTLGQGGSAITD 1621 N+ + + V + G N + +T + A ++ S Sbjct: 760 NIEI-----VGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASV-DASSGQVT 813 Query: 1622 INGKAEVTLSGTKSGTYPVTVSVN 1645 + K T+S S T ++ Sbjct: 814 LKEKGTTTISVISSDNQTATYTIA 837 Score = 65.9 bits (160), Expect = 2e-12 Identities = 76/359 (21%), Positives = 130/359 (36%), Gaps = 37/359 (10%) Query: 1432 YQVTATLENGDSMQQTVTYVPNVANAEITLAASKDPLIADNNDLT-----------TLTA 1480 Y + + Q + P N TL+ S+ L+ NN++ + Sbjct: 403 YSMQFRYQFDKPWSQQIE--PQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPH 460 Query: 1481 TVADTEGNA---IANTEVTFTLPEDVKANFTL-SDGGKAITDAEGKAK---VTLKGTKAG 1533 + TE + + + L V + L S GG+ A+ L G Sbjct: 461 DINGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQG 520 Query: 1534 AH-----TVTASMTGGKS---EQLVVNFIADTLSAQ----VNLNVTEDNFIANNVGMTTL 1581 T A G S L + +++ + + + A+ T Sbjct: 521 GSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITY 580 Query: 1582 QATVTDGNGNPLANEAVTFTLPADVSASFTLGQGGSAITDINGKAEVTLSGTKSGTYPVT 1641 ATV NG AN V+F + VS + L SA T+ +GKA VTL K G V+ Sbjct: 581 TATVKK-NGVAQANVPVSFNI---VSGTAVLSAN-SANTNGSGKATVTLKSDKPGQVVVS 635 Query: 1642 VSVNNYGVSDTKQVTLIADAGTATLASLTSVYSFVVSTTEGATMTASVTDANGNPVEGIK 1701 + + D A++ + + + V+ + A PV + Sbjct: 636 AKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQE 695 Query: 1702 VNFRGTSVTLSSTSVETDDQGFAEILVTSTEVGLKTVSASLADKPTEVISRLLNAKADI 1760 V F T LS+++ +TD G+A++ +TST G VSA ++D +V + + + Sbjct: 696 VTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTL 754 Score = 56.6 bits (136), Expect = 1e-09 Identities = 56/267 (20%), Positives = 90/267 (33%), Gaps = 11/267 (4%) Query: 1875 TGTTLTATLTSANGTPVEGQVINFSVTPEGATLSGGKVRTNSSGQAPVVLTSNKVGTYTV 1934 T TAT+ NG ++F++ A LS TN SG+A V L S+K G V Sbjct: 576 EAITYTATVKK-NGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVV 634 Query: 1935 TASFHNGVTIQTQTTVKVTGNSSTAHVASFIADPSTIAATNSDLSTLKATVEDGSGNLIE 1994 +A + + + + A + AD +T A D T V G + Sbjct: 635 SAKTAEMTS-ALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKG-DKPVS 692 Query: 1995 GLTVYFALKSGSATLTSLTAVTDQNGIATTSVKGAMTGSVTVSAVTTAGGMQ--TVDITL 2052 V F G + + T TD NG A ++ G VSA + + ++ Sbjct: 693 NQEVTFTTTLGKLSNS--TEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEF 750 Query: 2053 VAGPADTSQSVLKSNRSSLKGDYTDSAELRLVLHDISGNPIKVSEGMEFVQSGTNVPYIK 2112 ++ T + V SG K + + + + + Sbjct: 751 FTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYT----WRSANPAIASVD 806 Query: 2113 ISAIDYSLNINGDYKATVTSGGEGIAT 2139 S+ +L G +V S AT Sbjct: 807 ASSGQVTLKEKGTTTISVISSDNQTAT 833
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 148 bits (376), Expect = 5e-48 Identities = 66/200 (33%), Positives = 101/200 (50%), Gaps = 30/200 (15%) Query: 1 MRKLCAVILSAVVWLVAAGTPASAAEHQSTLSAGYLQTHTDMPGSDDLKGINVKYRYEFT 60 M+K+ + A V AGT +A ST++ GY Q+ + + G N+KYRYE Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAA---TSTVTGGYAQSDAQGQMNK-MGGFNLKYRYEED 56 Query: 61 DT-LGLVTSFSYANAKDEQKTHYSDTRWHEDSVRNRWFSMMAGPSVRVNEWFSAYAMAGV 119 ++ LG++ SF+Y T S T D +N+++ + AGP+ R+N+W S Y + GV Sbjct: 57 NSPLGVIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGV 108 Query: 120 AYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAWGAGVQFNPTESVAIDIAYE 179 Y + T T+ HD S+ ++GAG+QFNP E+VA+D +YE Sbjct: 109 GYGKFQT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYE 151 Query: 180 GSGSGDWRTDGFIVGVGYKF 199 S +I GVGY+F Sbjct: 152 QSRIRSVDVGTWIAGVGYRF 171
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 45.8 bits (108), Expect = 8e-07 Identities = 32/165 (19%), Positives = 54/165 (32%), Gaps = 15/165 (9%) Query: 209 ETAAKNSQVAAAQSESAAAGSA--TSAAGSATAAANSQKAAKTSETNAKSSQTAAKTSET 266 E +N V + A S + A +A A S+T +E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 267 NAKASETAAKNSQDA------------AAQSESAAAGSASAAASSATASANSQKAAKTSE 314 + + S+T KN QDA A+S A + A S + + +Q Sbjct: 1044 SKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKET 1103 Query: 315 TNAKASETAAANSAKASAASQTAAKASEDAAREYASQ-AAEPYKQ 358 + E A + K + ++ S + Q AEP ++ Sbjct: 1104 ATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARE 1148 Score = 45.1 bits (106), Expect = 1e-06 Identities = 32/183 (17%), Positives = 62/183 (33%), Gaps = 11/183 (6%) Query: 112 EEAARNAEAASQSAAAAKKSETAAASSKNAAKTSETNAANSAQAAATSQTASANSATAAK 171 E + E ++ + K E + A E + + + + +A++ AK Sbjct: 1114 VETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 172 KSETNAKNSETAAKTSETNAK-----SSQTAAKTSETNAKASETAAKNSQVAAAQSESAA 226 ++ +N + T + T T + T A T T S KN + +S Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHN 1233 Query: 227 AGSATSAAGSATAAANSQKAAKTSETNAKSSQTAAKTS----ETNAKASETAAKNSQDAA 282 AT+++ + A ++ TNA S AK S+ ++ + Sbjct: 1234 VEPATTSSNDRSTVA--LCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNE 1291 Query: 283 AQS 285 Q Sbjct: 1292 GQY 1294
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.1 bits (208), Expect = 1e-20 Identities = 30/117 (25%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Query: 39 KILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQ 98 IL+ +D+ + + Q LS AGY + S+ D L++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 99 ILQTLRTA-KQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQ 154 +L ++ A PV+ ++A+++ ++ + GA DYL KPF +EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>PF06580#Sensor histidine kinase Length = 349 Score = 33.3 bits (76), Expect = 0.002 Identities = 37/181 (20%), Positives = 61/181 (33%), Gaps = 37/181 (20%) Query: 290 ENILFLARADKNNVLVKLDSLS----------------LNKEVENLLDYL--EYLSDEKE 331 NI L D L SLS L E+ + YL + E Sbjct: 180 NNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDR 239 Query: 332 ICFKVECNQQIFADKI---LLQRMLSNLIVNAIRYSPEKSHIHITSFLDTNGYLNIDVAS 388 + F+ + N I ++ L+Q ++ N I + I P+ I + D NG + ++V + Sbjct: 240 LQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKD-NGTVTLEVEN 298 Query: 389 PGTKIHEPEKLFRRFWRGDNSRHSVGQGLGLSLVKA-IAELHGGSATYHYLNKHNVFRIT 447 G+ + K G GL V+ + L+G A K Sbjct: 299 TGSLALKNTKE--------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344 Query: 448 L 448 + Sbjct: 345 V 345
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 515 bits (1328), Expect = 0.0 Identities = 261/396 (65%), Positives = 309/396 (78%), Gaps = 22/396 (5%) Query: 1 MKRKVLAMLVPALLVAGAANAAEIYNKNGNKLDLYGKVDARHTFSDNPGDDGDETIIELG 60 MKRKVLA+++PALL AGAA+AAEIYNK+GNKLDLYGKVD H FSD+ DGD+T + +G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQITDQLTGYGQALTKTKASDTEG-SDNTYVKLAFAGLKFGEMGSFDYGRNYGVIY 119 FKGETQI DQLTGYGQ +A+ TEG N++ +LAFAGLKFG+ GSFDYGRNYGV+Y Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 120 DVEAWTDMLPVFGGDSYTWTDNFMAGRANGVATYRNSDFFGLVEGLNFALQYQGNNEGSN 179 DVE WTDMLP FGGDSYT+ DN+M GRANGVATYRN+DFFGLV+GLNFALQYQG NE + Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 180 AGEDQEGT--KNGHEDVRFQNGDGFGLSTSYDFDFGLSLGAAYSNSDRTNSQVALGGYHY 237 A + GT +N +D+R+ NGDGFG+ST+YD G S GAAY+ SDRTN QV GG Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGT-- 238 Query: 238 NEYSKFAGGDTAEAWTFGAKYDANNVYLAMMYAETRNMTPYG------NVGIANKTQNFE 291 AGGD A+AWT G KYDANN+YLA MY+ETRNMTPYG + G+ANKTQNFE Sbjct: 239 -----IAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFE 293 Query: 292 AVAQYQFDFGLRPSLAYVYSKGKDLGGNDYNNNGHQEYVDQDLVNYVEIGATYYFNKNFS 351 AQYQFDFGLRP+++++ SKGKDL N+ N D+DLV Y ++GATYYFNKNFS Sbjct: 294 VTAQYQFDFGLRPAVSFLMSKGKDLTYNNVN------GDDKDLVKYADVGATYYFNKNFS 347 Query: 352 TYVDYKINLLDKDDDFYDNNGIATDDVVGVGLVYQF 387 TYVDYKINLLD DD FY + GI+TDD+V +G+VYQF Sbjct: 348 TYVDYKINLLDDDDPFYKDAGISTDDIVALGMVYQF 383
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 34.4 bits (79), Expect = 2e-04 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 9/92 (9%) Query: 37 AQKLAADDDVDMLVILTACYFHDIVSLAKNHPQRQRSSILAAEETRRLLREEFEQFPA-- 94 +KLA + + D+ +ILT + +L + Q + EE R+ E F A Sbjct: 219 GEKLAEEVNADIFMILTDV---NGAALYYGTEKEQWLREVKVEELRKYYEE--GHFKAGS 273 Query: 95 --EKIEAVCHAIAAHSFSAQIAPLTTEAKIVQ 124 K+ A I A IA L + ++ Sbjct: 274 MGPKVLAAIRFIEWGGERAIIAHLEKAVEALE 305
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.047 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 15/62 (24%) Query: 320 AKYILTPVLWKYLYRYAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRG 379 A+Y + PVLW Y+ R+ K + G+ VY +R +DG+E RG Sbjct: 166 ARYQVGPVLWGYVVRFIK---SDGDKLTLPYVY------------SRSQRDGSEAWKWRG 210 Query: 380 WD 381 WD Sbjct: 211 WD 212
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 201 bits (514), Expect = 1e-66 Identities = 257/261 (98%), Positives = 261/261 (100%) Query: 1 MMQVTSDQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 M+QVTS+QWLSWL+LYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL Sbjct: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 Query: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC Sbjct: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 Query: 241 EHLFSEMFNLLADIISELPLI 261 EHLFSE+FNLLADIISELPLI Sbjct: 241 EHLFSEIFNLLADIISELPLI 261
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 67.1 bits (164), Expect = 1e-18 Identities = 22/78 (28%), Positives = 42/78 (53%) Query: 4 ESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQINEMTLSFIPKIIAVFIAII 63 + ++ G +A+ + L L+ +VA + GL++ + Q TQ+ E TL F K++ V + + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 IAGPWMLNLLLDYVRTLF 81 + W +LL Y R + Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 334 bits (858), Expect = e-119 Identities = 245/245 (100%), Positives = 245/245 (100%) Query: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 Query: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 Query: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK Sbjct: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 Query: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA Sbjct: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 Query: 241 QSFYS 245 QSFYS Sbjct: 241 QSFYS 245
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 211 bits (539), Expect = 3e-74 Identities = 125/137 (91%), Positives = 133/137 (97%) Query: 1 MSDMNNPADDNNGAMDDLWAEALSEQKSTNSKSAADAVFQQFGGGDVSGTLQDIDLIMDI 60 MSDMNNP+D+N GA+DDLWA+AL+EQK+T +KSAADAVFQQ GGGDVSG +QDIDLIMDI Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDI 60 Query: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV Sbjct: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 Query: 121 RITDIITPSERMRRLSR 137 RITDIITPSERMRRLSR Sbjct: 121 RITDIITPSERMRRLSR 137
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 381 bits (979), Expect = e-135 Identities = 85/324 (26%), Positives = 148/324 (45%), Gaps = 10/324 (3%) Query: 5 ILSQAEIDALLNGDS--EVKDEPTASVSGESDIRPYDPNTQRRVVRERLQALEIINERFA 62 +LSQ EID LL S + E +S I YD + +E+++ L +++E FA Sbjct: 4 VLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETFA 63 Query: 63 RHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNLNLIHLKPLRGTGLVVFSPSL 122 R L LR + V ++ Y EF R++P P+ L +I + PL+G ++ PS+ Sbjct: 64 RLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPSI 123 Query: 123 VFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKLALEGYSDAWKAINPLEVEYVRS 182 F +D LFGG G+ KV+ R+ T E V+ ++ L ++W + L + Sbjct: 124 TFSIIDRLFGGTGQ-AAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQI 181 Query: 183 EMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNICLPFSMIEPLRELLVNPPLENS--R 240 E +F I P+++VV ++G G N C+P+ IEP+ L + +S R Sbjct: 182 ETNPQFAQI-VPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRR 240 Query: 241 NEDQNWRDNLVRQVQHSQLELVANFADISLRLSQILKLKPGDVLPIEKP---DRIIAHVD 297 + + L ++ +++VA + L + IL L+ GD++ + D + + Sbjct: 241 SSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIG 300 Query: 298 GVPVLTSQYGTLNGQYALRIEHLI 321 Q G + + A +I I Sbjct: 301 NRKKFLCQPGVVGKKIAAQILERI 324
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 468 bits (1204), Expect = e-168 Identities = 365/375 (97%), Positives = 370/375 (98%) Query: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK Sbjct: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 Query: 61 GEPLVSEILADAQQADLLIPVDETPPVINDEQSTSTPLTTAQTMTLAAVAGNNTAKDEKA 120 GEPL+S+I++DAQQA+LLIPVDETPPVINDEQSTSTPLTTAQTM LAAVA NT KDEKA Sbjct: 61 GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA 120 Query: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAP 180 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAP Sbjct: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAP 180 Query: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW Sbjct: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 Query: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA 300 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA Sbjct: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA 300 Query: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTVNHEPLAGEDDDTLPVPVS 360 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRT NHEPLAGEDDDTLPVPVS Sbjct: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS 360 Query: 361 LQGRVTGNSGVDIFA 375 LQGRVTGNSGVDIFA Sbjct: 361 LQGRVTGNSGVDIFA 375
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 202 bits (515), Expect = 2e-70 Identities = 146/147 (99%), Positives = 147/147 (100%) Query: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 MTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 +TSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147 AALLAENRLDQKKMDEFAQRAAMRKPE Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 374 bits (961), Expect = e-136 Identities = 225/228 (98%), Positives = 228/228 (100%) Query: 1 MSDNLPWKTWTPDDLAPPQAEFVPMVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 MSDNLPWKTWTPDDLAPPQAEFVP+VEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI Sbjct: 1 MSDNLPWKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 Query: 61 AEGRQQGHEQGYQEGLARGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 AEGRQQGH+QGYQEGLA+GLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL Sbjct: 61 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 Query: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT Sbjct: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 Query: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV Sbjct: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 341 bits (876), Expect = e-119 Identities = 117/329 (35%), Positives = 197/329 (59%), Gaps = 2/329 (0%) Query: 1 MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFE 60 +S LTG K+ ILL++IG + +++VFK+LSQ E+++L+ +A + I+++ +VL EF+ Sbjct: 12 VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFK 71 Query: 61 QEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAAD 120 + + DY R +L K+LG ++A ++ + L + + E + +P + + Sbjct: 72 ELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINN-LGSALQSRPFEFVRRADPANILN 130 Query: 121 LIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLRIATFGGVQPAALAELTEVLN 180 I+ EHPQ IA IL +L +A+ IL+ ++ +V RIA P + E+ VL Sbjct: 131 FIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLE 190 Query: 181 GLLDGQ-NLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENL 239 L + + GGV EIIN+ + E+ +I ++ E D ELA++I +MF+FE++ Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDI 250 Query: 240 VDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLS 299 V +DDRSIQR+L+E+D + L ALK + P++EK +NMS+RAA +L++D+ GP R Sbjct: 251 VLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRK 310 Query: 300 QVENEQKAILLIVRRLAETGEMVIGSGED 328 VE Q+ I+ ++R+L E GE+VI G + Sbjct: 311 DVEESQQKIVSLIRKLEEQGEIVISRGGE 339
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 756 bits (1953), Expect = 0.0 Identities = 479/555 (86%), Positives = 515/555 (92%), Gaps = 5/555 (0%) Query: 3 ATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAKAPDYRTLFSNLSDQDGGA 62 +TA Q K LEWLNRLRANP+IPLIVAGSAAVA++VA++LWAK PDYRTLFSNLSDQDGGA Sbjct: 5 STATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGA 64 Query: 63 IVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 122 IV+QLTQMNIPYRF+ SGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ Sbjct: 65 IVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 124 Query: 123 FSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPSLFVREQKSPSASVTVNLLPGRA 182 FSEQVNYQRALEGEL+RTIET+GPVK ARVHLAMPKPSLFVREQKSPSASVTV L PGRA Sbjct: 125 FSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRA 184 Query: 183 LDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLTQSNTSGRDLNDAQLKYASDVEGRI 242 LDEGQISA+VHLVSSAVAGLPPGNVTLVDQ GHLLTQSNTSGRDLNDAQLK+A+DVE RI Sbjct: 185 LDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRI 244 Query: 243 QRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTEEQYRPNGDESHAALRSRQLNESEQSG 302 QRRIEAILSPIVGNGN+HAQVTAQLDFA+KEQTEE Y PNGD S A LRSRQLN SEQ G Sbjct: 245 QRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVG 304 Query: 303 SGYPGGVPGALSNQPAPANNAPISTPPANQNNRQQ--QASTTSNS---GPRSTQRNETSN 357 +GYPGGVPGALSNQPAP N API+TPP NQ N Q Q ST++NS GPRSTQRNETSN Sbjct: 305 AGYPGGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSN 364 Query: 358 YEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGKPLPLSNEQMKQIEDLTREAMGFSEK 417 YEVDRTIRHTKMNVGD++RLSVAVVVNYKTL DGKPLPL+ +QMKQIEDLTREAMGFS+K Sbjct: 365 YEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMGFSDK 424 Query: 418 RGDSLNVVNSPFNSSDESGGELPFWQQQAFIDQLLAAGRWLLVLLVAWLLWRKAVRPQLT 477 RGD+LNVVNSPF++ D +GGELPFWQQQ+FIDQLLAAGRWLLVL+VAW+LWRKAVRPQLT Sbjct: 425 RGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLT 484 Query: 478 RRAEAMKAVQQQAQAREEVEDAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR 537 RR E KA Q+QAQ R+E E+AVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR Sbjct: 485 RRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR 544 Query: 538 VVALVIRQWINNDHE 552 VVALVIRQW++NDHE Sbjct: 545 VVALVIRQWMSNDHE 559
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 117 bits (294), Expect = 5e-38 Identities = 103/103 (100%), Positives = 103/103 (100%) Query: 2 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 61 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL Sbjct: 1 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 60 Query: 62 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 104 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV Sbjct: 61 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 30.0 bits (67), Expect = 6e-04 Identities = 9/37 (24%), Positives = 17/37 (45%), Gaps = 5/37 (13%) Query: 4 LSWIIFGLIAGILAKWIMPG-----KDGGGFFMTILL 35 + I+ G I+G++ W+ K ++ ILL Sbjct: 163 AAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILL 199
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 27.7 bits (61), Expect = 0.022 Identities = 18/61 (29%), Positives = 26/61 (42%) Query: 49 QGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGS 108 Q +I L IG + + LPPS ++ N ++ A VS LG +TL G Sbjct: 174 QRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGG 233 Query: 109 Q 109 Sbjct: 234 H 234
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 28.9 bits (64), Expect = 0.023 Identities = 18/81 (22%), Positives = 34/81 (41%), Gaps = 13/81 (16%) Query: 158 ETTSALHTYFNVGDITKVSVSGLGDRFIDKVNDAKED-----------VLTDGIQTFPDR 206 E ++AL + N D K S S L + F ++V + + V ++ F + Sbjct: 57 EMSAALAQFRNRRDYEKKS-SNLSNSF-ERVLEDEALPKAKQILKLISVHGGALEDFLRQ 114 Query: 207 TDRVYLNPQDCSVINDEALNR 227 ++ +P D ++ E L R Sbjct: 115 ARSLFPDPSDLVLVLRELLRR 135
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.011 Identities = 33/142 (23%), Positives = 48/142 (33%), Gaps = 23/142 (16%) Query: 71 MFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDF-LIACRFVMGVGLGALL 129 +G V G + D+ G + + I+ V+G + LI RF+ G G A Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121 Query: 130 VTLFAGFTEYMPGRNR----GTWSSRVSFIGNWSYPLCSLIAMGLTPLISA----EWNWR 181 + Y+P NR G S V+ + G+ P I +W Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVA------------MGEGVGPAIGGMIAHYIHWS 169 Query: 182 VQLLIPAILSLIATALAWRYFP 203 LLIP I I T Sbjct: 170 YLLLIPMI--TIITVPFLMKLL 189
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 31.2 bits (71), Expect = 0.002 Identities = 14/61 (22%), Positives = 28/61 (45%), Gaps = 5/61 (8%) Query: 74 SNKAELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHR 133 +NK +L A +A T + ++A V A+ + ++ + GE+ + G +R R Sbjct: 2 ANKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAK-----GEKVQLIGFGNFEVRER 56 Query: 134 P 134 Sbjct: 57 A 57
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 41.9 bits (98), Expect = 3e-07 Identities = 22/112 (19%), Positives = 47/112 (41%), Gaps = 4/112 (3%) Query: 34 FEEPYEAFVELSDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHVHRRAEFQ-IIISP 92 F +PY E D+ ++ ++ + F+ + G +++ + + A + I ++ Sbjct: 42 FSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRS--NWNGYALIEDIAVAK 99 Query: 93 EYQGKGLATRAAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFTVEG 144 +Y+ KG+ T A+++ + L L N A H Y K F + Sbjct: 100 DYRKKGVGTALLHKAIEWAKEN-HFCGLMLETQDINISACHFYAKHHFIIGA 150
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 48.7 bits (116), Expect = 3e-08 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 16/118 (13%) Query: 72 VGAFIFGKMGDRIGRKKVLFITITMMGICTTLIGVLPTYAQIGVFAPILLVTLRIIQGLG 131 +G ++GK+ D++G K++L I + + + V ++ + + A R IQG G Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMA-------RFIQGAG 116 Query: 132 AGAEISGAGTMLAEYAPKGKR----GIISSFVAMGTNCGTLSATAI-----WAFMFFI 180 A A + ++A Y PK R G+I S VAMG G I W+++ I Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI 174
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 99.7 bits (248), Expect = 2e-27 Identities = 70/244 (28%), Positives = 114/244 (46%), Gaps = 16/244 (6%) Query: 2 IVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQ---LDVRNR 58 I +TGA G GE + R QG + A E+L+++ L A+ DVR+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 59 AAIEEMLASLPAEWCNIDILVNNAGLALGMEPAHKASVEDWETMIDTNNKGLVYMTRAVL 118 AAI+E+ A + E IDILVN AG+ L H S E+WE N+ G+ +R+V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 119 PGMVERNYGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDIEPG 178 M++R G I+ +GS P Y ++KA F+ L +L +R + PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 179 LVGGTEFSNVRFKGDDGKAE------KTYQNTVALT----PEDVSEAV-WWVSTLPAHVN 227 T+ + ++G + +T++ + L P D+++AV + VS H+ Sbjct: 189 ST-ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 228 INTL 231 ++ L Sbjct: 248 MHNL 251
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.3 bits (97), Expect = 4e-06 Identities = 41/235 (17%), Positives = 82/235 (34%), Gaps = 10/235 (4%) Query: 7 RSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLI---GYAMTIALTIGVVFSLGF 63 R +L++ L +G G +P + L R S D+ G + + + + Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLL-RDLVHSNDVTAHYGILLALYALMQFACAPVL 63 Query: 64 GILADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLFFALINCAYSVFATVLKAWFAD 123 G L+D+F ++ +L+++ A + + + ++ + + + A A+ AD Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIAD 122 Query: 124 NLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSINLPFWLAAICSAFPMLFIQIWVK 183 + + F G GP LG L+ S + PF+ AA + L + Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 184 RSEKIIAT-ETGRAWSPKVLLQDKALL----WFTCSGFLASFVSGAFASCISQYV 233 S K A +P + + F+ V A+ + Sbjct: 183 ESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG 237 Score = 32.1 bits (73), Expect = 0.003 Identities = 22/155 (14%), Positives = 60/155 (38%), Gaps = 2/155 (1%) Query: 7 RSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLIGYAMTIALTIGVVF-SLGFGI 65 +AL+A ++ + I+ ++ IG ++ + + ++ G Sbjct: 210 TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 66 LADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLFFALINCAYSVFATVLKAWFADNL 125 +A + ++R ++L + A +G+I + + L+ + L+A + + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG-GIGMPALQAMLSRQV 328 Query: 126 SSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI 160 + ++ + ++ +GP L T + SI Sbjct: 329 DEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASI 363
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 62.8 bits (152), Expect = 9e-12 Identities = 82/349 (23%), Positives = 124/349 (35%), Gaps = 35/349 (10%) Query: 1271 QGTTDIVGGEIAFGSDSAINMASQHINIHNSGVMSGNVTTAGDVNVMPGGTLRVAKTTVG 1330 DIV E+ S ++ + + + +G +++ + + VG Sbjct: 392 DAQGDIVATELP--SIPGTSIGPLDVALASQARWTGATRAVDSLSIDNATWVMTDNSNVG 449 Query: 1331 G-NLENGGTVQMNSEGGKPGNVLTVNGNYTGNNGLMTFNATLGGDNSPTDKMNVKGDTQG 1389 L + G+V G + N +GL N D +DK+ V D G Sbjct: 450 ALRLASDGSVDFQQPAEA-GRFKVLTVNTLAGSGLFRMNVFA--DLGLSDKLVVMQDASG 506 Query: 1390 NTRVRVDNIGGVGAQTVNGIELIEVGGNSAGNFALTT--GTVEAGAYVYTLAKGKGNDEK 1447 R+ V N G + N + L++ SA F L G V+ G Y Y LA N Sbjct: 507 QHRLWVRNSGS-EPASANTLLLVQTPLGSAATFTLANKDGKVDIGTYRYRLAA---NGNG 562 Query: 1448 NWYLTSKWDGVTPADTPDPINNPPVVDPEGPS--VYRPEAGSYIS----------NIAAA 1495 W L P P P PP P +P AG +S + A Sbjct: 563 QWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVGLA 622 Query: 1496 NSLF---SHRLHDRLGEPQYTDSLRVQDSATSMWMRHVGGHERFRTGDGQLNTQANRYVL 1552 ++L+ S+ L RLGE LR+ A W R ++ G+ Q Sbjct: 623 STLWYAESNALSKRLGE------LRLNPDAGGAWGRGFAQRQQLDNRAGRRFDQ-KVAGF 675 Query: 1553 QLGGDLAQWSSTQDRWHLGVMAGYANQHSNTQSNHVGYKSDGRISGYSA 1601 +LG D A + RWHLG +AGY + G+ + GY+ Sbjct: 676 ELGADHA-VAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYAT 723
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 940 bits (2432), Expect = 0.0 Identities = 498/869 (57%), Positives = 654/869 (75%), Gaps = 10/869 (1%) Query: 3 QVLLLPRFARLTIALGLATAVFPVDAEFYFNPRFLSNDLAESVDLSAFTKGREAPPGTYR 62 + L F RL +A A AE YFNPRFL++D DLS F G+E PPGTYR Sbjct: 20 KHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYR 79 Query: 63 VDIYLNDEFMTSRDITFIADDNNADLIPCLSTDLLVSLGIKKSALLDNKEHSAEKHVSDN 122 VDIYLN+ +M +RD+TF D+ ++PCL+ L S+G+ +++ + ++ + Sbjct: 80 VDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASV-------SGMNLLAD 132 Query: 123 SACTPLRDRLADASSEFNVGQQHLSLSVPQIYVGRMARGYVSPDLWEEGINAGLLNYSFN 182 AC PL + DA+++ +VGQQ L+L++PQ ++ ARGY+ P+LW+ GINAGLLNY+F+ Sbjct: 133 DACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFS 192 Query: 183 GNSINNRGNHNAGKSNYAYLNLQSGINIGSWRLRDNSTWSYNSGSSNSSDSNKWQHINTS 242 GNS+ NR G S+YAYLNLQSG+NIG+WRLRDN+TWSYNS S+S NKWQHINT Sbjct: 193 GNSVQNRI---GGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTW 249 Query: 243 AERDIIPLRSRLTVGDSYTDGDIFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIARSTA 302 ERDIIPLRSRLT+GD YT GDIFD +NFRG ++ S + MLPDSQ GFAPVIHGIAR TA Sbjct: 250 LERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTA 309 Query: 303 QVSVKQNGYDVYQTTVPPGPFTIDDINSAANGGDLQVTIKEADGSIQTLYVPYSSVPVLQ 362 QV++KQNGYD+Y +TVPPGPFTI+DI +A N GDLQVTIKEADGS Q VPYSSVP+LQ Sbjct: 310 QVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQ 369 Query: 363 RAGYTRYALAMGEYRSGNNLQSSPKFIQGSLMHGLEGNWTPYGGMQIAEDYQAFNLGIGK 422 R G+TRY++ GEYRSGN Q P+F Q +L+HGL WT YGG Q+A+ Y+AFN GIGK Sbjct: 370 REGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGK 429 Query: 423 DLGLFGAFSFDITQANTTLADGTRHSGQSIKSVYSKSFYQTGTNIQVAGYRYSTQGFYNL 482 ++G GA S D+TQAN+TL D ++H GQS++ +Y+KS ++GTNIQ+ GYRYST G++N Sbjct: 430 NMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNF 489 Query: 483 SDSAYSRMSGYTVKPPTGDSNEQTQFIDYFNLFYSKRGQEQISISQQLGNYGTTFFSASR 542 +D+ YSRM+GY ++ G + +F DY+NL Y+KRG+ Q++++QQLG T + S S Sbjct: 490 ADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSH 549 Query: 543 QSYWNTSRSDQQISFGLNVPFSDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTD 602 Q+YW TS D+Q GLN F DI +L+YS + N WQ RD +LA +N+PFSHW+R+D Sbjct: 550 QTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSD 609 Query: 603 SQSAFRNSNASYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTHGGNTSSGTSGYS 662 S+S +R+++ASYSMS+DL G MTNL+GVYGTLL DNNL+YSVQ G GG+ +SG++GY+ Sbjct: 610 SKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYA 669 Query: 663 SLNYRGAYGNTNIGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNV 722 +LNYRG YGN NIGYS S D Q+YYG+SGG++AHA+G+T GQPL DT+VLVKAPGA + Sbjct: 670 TLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDA 729 Query: 723 KIENQTGIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARAT 782 K+ENQTG+ TDWRGYA+LP+ATEYRENRVAL+ N+LADNV+LD V V+PT GAI RA Sbjct: 730 KVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAE 789 Query: 783 FNAQIGGKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGN 842 F A++G K+LMTL + NK +PFGA+VT +++ IVA+NGQVYL+G+P +GK+QV WG Sbjct: 790 FKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGE 849 Query: 843 DKNSNCIVDYKLPAVSPGTLLNQQTAICR 871 ++N++C+ +Y+LP S LL Q +A CR Sbjct: 850 EENAHCVANYQLPPESQQQLLTQLSAECR 878
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 32.4 bits (73), Expect = 6e-04 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 7/93 (7%) Query: 16 LFTATLQAADVTITVIGRVVAKPCTIQT-KEANVNLGDLYTRNLQQPGSASGWHNITLSL 74 L T+ ADV I + G V PCTI + V+ G++ N + ++ G +S+ Sbjct: 11 LLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNI---NPEHVDNSRGEVTKNISI 67 Query: 75 TDCPVETSAVTAIVTGSTDNTGYYKNEGTAENI 107 + CP ++ ++ VTG+T G +N A NI Sbjct: 68 S-CPYKSGSLWIKVTGNTMGVG--QNNVLATNI 97
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 479 bits (1234), Expect = e-172 Identities = 225/386 (58%), Positives = 271/386 (70%), Gaps = 23/386 (5%) Query: 1 MKLKIVAVVVTGLLAANVAHAAEVYNKDGNKLDLYGKVTALRYFTDDKRDDGDKTYARLG 60 MK K++A+V+ LLAA AHAAE+YNKDGNKLDLYGKV L YF+DD DGD+TY R+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQINDQMIGFGHWEYDFKGYNDEANGSRGNKTRLAYAGLKISEFGSLDYGRNYGVG 120 FKGETQINDQ+ G+G WEY+ + E G+ + TRLA+AGLK ++GS DYGRNYGV Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGAN-SWTRLAFAGLKFGDYGSFDYGRNYGVL 119 Query: 121 YDIGSWTDMLPEFGGDTWSQKDVFMTYRTTGVATYRNYDFFGLIEGLNFAAQYQGKNER- 179 YD+ WTDMLPEFGGD+++ D +MT R GVATYRN DFFGL++GLNFA QYQGKNE Sbjct: 120 YDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQ 179 Query: 180 -------TDNGHLYGADYTRANGDGFGISSTYVYD-GFGIGAVYTKSDRTNAQERAAANP 231 N G D NGDGFGIS+TY GF GA YT SDRTN Q A Sbjct: 180 SADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGT- 238 Query: 232 LNASGKNAELWATGIKYDANNIYFAANYAETLNMTTYG------DGYISNKAQSFEVVAQ 285 A G A+ W G+KYDANNIY A Y+ET NMT YG DG ++NK Q+FEV AQ Sbjct: 239 -IAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQ 297 Query: 286 YQFDFGLRPSLAYLKSKGRDLGR----YGDQDMIEYIDVGATYFFNKNMSTYVDYKINLI 341 YQFDFGLRP++++L SKG+DL D+D+++Y DVGATY+FNKN STYVDYKINL+ Sbjct: 298 YQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLL 357 Query: 342 DESD-FTRAVDIRTDNIVATGITYQF 366 D+ D F + I TD+IVA G+ YQF Sbjct: 358 DDDDPFYKDAGISTDDIVALGMVYQF 383
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 24.6 bits (53), Expect = 0.030 Identities = 7/43 (16%), Positives = 17/43 (39%) Query: 30 SGRSELSQSEQQRLAQLADEAKRMRERIQALESILDAEHPNWR 72 +G+ + + A A++A + + E L + +W Sbjct: 37 AGQLGIEATGSGVCAGPAEQANALAGDVACAEQWLGDKPVSWS 79
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 342 bits (880), Expect = e-118 Identities = 126/341 (36%), Positives = 182/341 (53%), Gaps = 23/341 (6%) Query: 6 DNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNC 65 L+G + + E+ ++ L D ++I GE GTGKEL+A LH R GPF+++N Sbjct: 137 MPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINM 196 Query: 66 AALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGGTLFLDELATAPMMVQEKLLRVIE 125 AA+ +L++SELFGHE GAFTGAQ R GRFE+A+GGTLFLDE+ PM Q +LLRV++ Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQ 256 Query: 126 YGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESD 185 GE VGG P++ +VR+V ATN DL +N+G FR DL RL ++LPPLR+R D Sbjct: 257 QGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAED 316 Query: 186 IMLMAEHFAIQMCREIKLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRHGTSDY 245 I + HF Q +E F + A E + + WPGN+REL+N+V R + Sbjct: 317 IPDLVRHFVQQAEKEGLDVK--RFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVI 374 Query: 246 PLDDIIID---PFKRRPPEDAIAVSETTSLPTLPLD------------------LREFQM 284 + I + P E A A S + S+ + Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLA 434 Query: 285 QQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI 325 + E L+ +L + NQ +AA+LLGL + R +++ + Sbjct: 435 EMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 252 bits (644), Expect = 5e-87 Identities = 233/239 (97%), Positives = 236/239 (98%), Gaps = 1/239 (0%) Query: 6 MTLDLPRRFPWPTLLSVCIHGAVVAGLIYTSVHQVIELPAPAQPISVTMVAPADLEPPQA 65 MTLDLPRRFPWPTLLSVCIHGAVVAGL+YTSVHQVIELPAPAQPISVTMV PADLEPPQA Sbjct: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 60 Query: 66 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQ-PKRDVKPVESR 124 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKV++ PKRDVKPVESR Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 Query: 125 PASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 184 PASPFENTAPAR TSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF Sbjct: 121 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 180 Query: 185 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 243 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ Sbjct: 181 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 239
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 31.2 bits (70), Expect = 4e-04 Identities = 16/57 (28%), Positives = 20/57 (35%), Gaps = 2/57 (3%) Query: 41 GPMPAVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKV 97 P+PA G GS E + EA W +P A V +V KV Sbjct: 268 APLPA--EGKFAVIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKV 322
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 42.0 bits (98), Expect = 9e-08 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Query: 8 TRSIYRELGATLSYNMRLGNGMEVEPWLKAAVRKEFVDDNRVKVNNDGNFVNDLSGRRGI 67 S+ LG + + L G +V+P++KA+V +EF V N + +L G R Sbjct: 811 GSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAH-RTELRGTRAE 869 Query: 68 YQAGIKASFSSSLSGHLGVGYSHGAGVESPWNAVAGANWSF 108 G+ A+ S + YS G + PW AG +S+ Sbjct: 870 LGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 102 bits (256), Expect = 2e-24 Identities = 145/653 (22%), Positives = 226/653 (34%), Gaps = 89/653 (13%) Query: 137 DVDITTHGDNAHAIAARQGTVSFNQGEIHTTGPDAAIAKIYNGGKVTLKNTSAVAHQGAG 196 D + + +V Q + AAI + G +VT+ S A G Sbjct: 285 PGGFGPVLDGWYGVDVSGSSVELAQSIVEAPELGAAIR-VGRGARVTVSGGSLSAPHGNV 343 Query: 197 IVLESSIN--GQEATVDILSGSSLRSANEILYNKNETSNVTITDSEVSSAADVFINNIKG 254 I + Q A + I + + + L + V +T ++ AD + + Sbjct: 344 IETGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKLT---LTGGADAQGDIVAT 400 Query: 255 HLVIDASNSKITGSANLSTD----DSTHTYLSLS-DNSTWDIKTDSTVS--KLTVDNSTV 307 L S L++ +T SLS DN+TW + +S V +L D S Sbjct: 401 ELPSIPGTSIGPLDVALASQARWTGATRAVDSLSIDNATWVMTDNSNVGALRLASDGSVD 460 Query: 308 YISRADGKAFEPTRLTITENYVGNNGVLHLRTELGDDNSATDKVVINGNTSGTTRVKVTN 367 + A+ F+ +T N + +G+ + D +DK+V+ + SG R+ V N Sbjct: 461 FQQPAEAGRFK----VLTVNTLAGSGLFRMNVFA--DLGLSDKLVVMQDASGQHRLWVRN 514 Query: 368 AGGSGAYTLNGIEIISVEGESNGEFI---KDSRIFAGAYEYSLTRGNTEATNKNWYLTNF 424 +G S + N + ++ S F KD ++ G Y Y L N W L Sbjct: 515 SG-SEPASANTLLLVQTPLGSAATFTLANKDGKVDIGTYRYRLA----ANGNGQWSLVGA 569 Query: 425 QAT-------SGGETNSGGSSAPTVAPTPVLRPEAGSYVANLAAANTLFVMRLNDRAGET 477 +A G AP P A AA NT V A Sbjct: 570 KAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGV----GLASTL 625 Query: 478 RYIDPVTEQERSSRLWLRQIGGHNAWRDSNGQLRTTSHRY-------VS--QLGADLLTG 528 Y + +R L L G AW Q + +R V+ +LGAD Sbjct: 626 WYAESNALSKRLGELRLNPDAG-GAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVA 684 Query: 529 GFTDSDSWRLGVMAGYARDYNSTHSSVSDYRSKGSVRGYSAGLYATWFADDISKKGAYID 588 W LG +AGY R + G G YAT+ AD G Y+D Sbjct: 685 VAGGR--WHLGGLAGYTR----GDRGFTGDGG-GHTDSVHVGGYATYIADS----GFYLD 733 Query: 589 AWAQYSWFKN----------SVKGDELAYESYSAKGATVSLEAGYGFALNKSFGLEAAKY 638 A + S +N +VKG Y G SLEAG F Sbjct: 734 ATLRASRLENDFKVAGSDGYAVKGK------YRTHGVGASLEAGRRFTHADG-------- 779 Query: 639 TWIFQPQAQAIWMGVDHNAHTEANGSRIENDANNNFQTRLGFRTFIRTQEKNSGPHGDDF 698 W +PQA+ A+ ANG R+ ++ ++ RLG R + G Sbjct: 780 -WFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAG----GRQV 834 Query: 699 EPFVEMNWIHNSK-DFAVSMNGVKVEQDGARNLGEIKLGVNGNLNPSASVWGN 750 +P+++ + + V NG+ + E+ LG+ L S++ + Sbjct: 835 QPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYAS 887
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 65.9 bits (160), Expect = 8e-13 Identities = 49/261 (18%), Positives = 83/261 (31%), Gaps = 26/261 (9%) Query: 551 VAPAPKAATATPASPAQPGLLSRFFSALKALFSGGEETKPAEQP-APKAEAKPERQQDRR 609 T P + S E + E P P A A P Sbjct: 991 TVDTTNITTPNNIQADVPSVPSN----------NEEIARVDEAPVPPPAPATPSETT--- 1037 Query: 610 KPRQNNRRDRNERRDSRSERTEGSDNREENRRNRRQAQQQTVETRESRQQAEV------T 663 N +++S++ D E +NR A++ + + Q EV T Sbjct: 1038 -----ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET 1092 Query: 664 EKARTTDEQQAPRRERSRRRNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQR 723 ++ +TT+ ++ E+ + + + Q+ K + + QE + + + R Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPK-VTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 724 QLNQKVRYEQSVAEEAVVAPVVEETVAGEPIVQEAPAPRTELVKVPLPVVAQAAPEQQEE 783 +N K Q+ P E + E V E+ T V P A Q Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTV 1211 Query: 784 NNADNRDNGGMPRRSRRSPRH 804 N+ + RRS RS H Sbjct: 1212 NSESSNKPKNRHRRSVRSVPH 1232 Score = 38.9 bits (90), Expect = 1e-04 Identities = 50/315 (15%), Positives = 91/315 (28%), Gaps = 34/315 (10%) Query: 516 EEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPK------------------- 556 + + E+ A A P PPAP VA K Sbjct: 1006 DVPSVPSNNEEIARVDEA-PVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQ 1064 Query: 557 ----AATATPASPAQPGLLSRFFSALKALFSGGEETKPAEQPAPKAEAKPERQQDRRKPR 612 A A A S + + ETK + +AK E ++ + P+ Sbjct: 1065 NREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPK 1124 Query: 613 QNNRRDRNERRDSRSERTEGSDNREEN-RRNRRQAQQQTVETRESRQQAEVTEKARTTDE 671 ++ + + S + + + RE + N ++ Q QT T ++ Q A+ T + E Sbjct: 1125 VTSQVSPKQEQ-SETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKET---SSNVE 1180 Query: 672 QQAPRRERSRRRNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRY 731 Q N + A + E+ + + R + R N + Sbjct: 1181 QPVTESTTVNTGNSVVENPENTTPA-TTQPTVNSESSNKPKNRHRRSVRSVPH-NVEPAT 1238 Query: 732 EQSVAEEAVVAPVVEETVAGEPIVQEAPAPRTELVKVPLPV---VAQAAPEQQEENNADN 788 S V + T + + + V V ++Q + + N Sbjct: 1239 TSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYNVWV 1298 Query: 789 RDNGGMPRRSRRSPR 803 + S R Sbjct: 1299 SNTSMNKNYSSSQYR 1313 Score = 35.4 bits (81), Expect = 0.001 Identities = 33/232 (14%), Positives = 69/232 (29%), Gaps = 15/232 (6%) Query: 515 EEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKAATATPASPAQPGLLSRF 574 E+E + E+ V P +E P PA + Q Sbjct: 1107 EKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQ----- 1161 Query: 575 FSALKALFSGGEETKPAEQPAPKAEAKPERQQDR--RKPRQNNRRDRNERRDSRSERTEG 632 + A + + P E+ + P +S S Sbjct: 1162 -TNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPK 1220 Query: 633 SDNREENRRNRRQAQQQTVETRESRQQAEVTEKARTTDEQQAPRRERSRRRNDDKRQAQQ 692 + +R R + T + + A + T+ + R +++ + +A Sbjct: 1221 NRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVS 1280 Query: 693 EAKA---LNVEEQS---VQETEQEERVRPVQPRRKQRQLNQ-KVRYEQSVAE 737 + + +N E Q V T + Q RR + Q ++ ++Q+++ Sbjct: 1281 QHISQLEMNNEGQYNVWVSNTSMNKNYSSSQYRRFSSKSTQTQLGWDQTISN 1332
>FLAGELLIN#Flagellin signature. Length = 507 Score = 47.3 bits (112), Expect = 4e-08 Identities = 42/226 (18%), Positives = 80/226 (35%), Gaps = 9/226 (3%) Query: 7 MMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPIAASQAVVLSQAQAQNSQYTLAR 66 ++ Q N+ +S + + E++S+G R+ + DD + A + +Q + Sbjct: 11 LLTQNNLNKSQSSLSSAI---ERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNA 67 Query: 67 TFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTLSDDDRASLATDIQGLRDQLLNLAN 126 E L+++ +Q +E V A+NGT SD D S+ +IQ +++ ++N Sbjct: 68 NDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSN 127 Query: 127 TTDGNGRYIFAGYKTESAPFSEVDGKYEGGAESIKQQVDASRSMVIGHTGDKIFDSITSN 186 T NG + + DG E+I + +G G + + Sbjct: 128 QTQFNGVKVLSQDNQMKIQVGANDG------ETITIDLQKIDVKSLGLDGFNVNGPKEAT 181 Query: 187 AVAEPDGSASETNLFAMLDSAIAALKTPVADSEADKETAAAALDKT 232 + T A + + TA DK Sbjct: 182 VGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKV 227
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 681 bits (1758), Expect = 0.0 Identities = 543/546 (99%), Positives = 544/546 (99%) Query: 2 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 61 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 62 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 121 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 122 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 181 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 182 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 241 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 242 RQLAAVPSSADPSRTTVAYIDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 301 RQLAAVPSSADPSRTTVAY+DGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 302 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 361 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 360 Query: 362 YKISFDNNQWQATRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 421 YKISFDNNQWQ TRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV Sbjct: 361 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 420 Query: 422 NMDVLITDEAKIAMASEEDVGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 481 NMDVLITDEAKIAMASEED GDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN Sbjct: 421 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 480 Query: 482 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 541 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD Sbjct: 481 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 540 Query: 542 ALINIR 547 ALINIR Sbjct: 541 ALINIR 546
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 508 bits (1310), Expect = 0.0 Identities = 310/313 (99%), Positives = 311/313 (99%) Query: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG Sbjct: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 Query: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESMPAAPMKFPLET 120 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEES PAAPMKFPLET Sbjct: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 Query: 121 VVRYQNQTLSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 VVRYQNQ LSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL Sbjct: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 Query: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL Sbjct: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 Query: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTSMIQQMKSISDK 300 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLT+MIQQMKSISDK Sbjct: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 Query: 301 VSKTYSMNIDNLF 313 VSKTYSMNIDNLF Sbjct: 301 VSKTYSMNIDNLF 313
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 425 bits (1095), Expect = e-151 Identities = 156/363 (42%), Positives = 212/363 (58%), Gaps = 9/363 (2%) Query: 4 FLSALILLLVTTAVQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLN 63 F + L RI+D+ S+Q R N LIGYGLVVGL GTGD +PFT Q++ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 64 NMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLM 123 ML LGIT G + KN+AAVMVTA+LPPF G +DV VSS+G+A SLRGG L+M Sbjct: 73 AMLQNLGITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIM 131 Query: 124 TPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGN 183 T L G D Q+YA+AQG ++V G A +++ R+ NGA+IERELPS+F Sbjct: 132 TSLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSV 191 Query: 184 TLNLQLNDEDFSMAQQIADTINRVR----GYGSATALDARTIQVRVPSGNSSQVRFLADI 239 L LQL + DFS A ++AD +N G A D++ I V+ P + R +A+I Sbjct: 192 NLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRV-ADLTRLMAEI 250 Query: 240 QNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGG 299 +N+ V T AKVVIN RTG++V+ +V + AV+ G L+V V V QP PF Sbjct: 251 ENLTVE-TDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSR 308 Query: 300 GQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLR 359 GQT V PQT I Q G + ++ L +V LN++G +++ILQ ++SAG L+ Sbjct: 309 GQTAVQPQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQ 367 Query: 360 AKL 362 A+L Sbjct: 368 AEL 370
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 349 bits (896), Expect = e-125 Identities = 231/232 (99%), Positives = 232/232 (100%) Query: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY Sbjct: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 Query: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKSNFGFDTVPRYLQGLFGNA 120 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGK+NFGFDTVPRYLQGLFGNA Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 Query: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF Sbjct: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 Query: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM Sbjct: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 3 SSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTL 62 S + A +GL+A Q ++ +NN+++ + G+ RQ + + +TL Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTL 47 Query: 63 PSGLQIGTGVRPVATERLHSQ 83 +G +G GV +R + Sbjct: 48 GAGGWVGNGVYVSGVQREYDA 68 Score = 41.1 bits (96), Expect = 3e-06 Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 220 ETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL 260 S VN+ EE N+ + Q+ Y N++ + T + + L + Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.5 bits (97), Expect = 4e-06 Identities = 17/49 (34%), Positives = 29/49 (59%) Query: 353 TLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQILNTLVNLR 401 L+N S V+L +E N+ Q+ Y +NAQ ++T + I + L+N+R Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 37.2 bits (86), Expect = 1e-04 Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 6 AVSGLNAAATNLDVIGNNIANSATYGFKSGTASFAD----MFAGSKVGLGVKVAGI 57 A+SGLNAA L+ NNI++ G+ T A + AG VG GV V+G+ Sbjct: 7 AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.8 bits (160), Expect = 2e-15 Identities = 30/165 (18%), Positives = 62/165 (37%), Gaps = 8/165 (4%) Query: 10 GKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAV 69 K + ++ IL AL FSQ G T L +IA+ AGV++ + ++F K L+ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 70 LRQILDIWLAPLKAFREDF--APLAAIKEYIRLKLEVSRDYPQASRLFCM-----EMLAG 122 ++ F PL+ ++E + LE + + L + E + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 123 APLLMDELTGDLKALIDEKSALIAGWVKSGKL-APIDPQHLIFMI 166 ++ D + +++ L A + + ++ Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM 167
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 75.8 bits (186), Expect = 2e-18 Identities = 46/176 (26%), Positives = 72/176 (40%), Gaps = 23/176 (13%) Query: 13 TFDPQQTALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQ 72 DP + L++ DMQN + +D S + ANI+ G+ +++ Sbjct: 25 VPDPNRAVLLIHDMQNYF------VDAFTAGASPVTELSANIRKLKNQCVQLGIPVVY-- 76 Query: 73 NGWDAQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVL 132 AQ PGS N L G L G ++ +++ EL P+ D+VL Sbjct: 77 ---TAQ------PGSQNPDDRALLTDF------WGPGLNSGPYEEKIITELAPEDDDLVL 121 Query: 133 PKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDA 188 K RYS F T L ++R G L+ TGI ++ T + F + + DA Sbjct: 122 TKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDA 177
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 609 bits (1571), Expect = 0.0 Identities = 338/350 (96%), Positives = 340/350 (97%), Gaps = 4/350 (1%) Query: 9 MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFIPNNGPTHENQLGAGA 68 MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFI NNGPTHENQLGAGA Sbjct: 1 MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGA 60 Query: 69 FGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTAKLGYPITDDLDVYTRLGG 128 FGGYQVNPYVGFEMGYDWLGRMPYKG NGAYKAQGVQLTAKLGYPITDDLD+YTRLGG Sbjct: 61 FGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGG 120 Query: 129 MVWRADTKSNVPGGASTKDHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGT 188 MVWRADTKSNV G K+HDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGT Sbjct: 121 MVWRADTKSNVYG----KNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGT 176 Query: 189 RPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQA 248 RPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQA Sbjct: 177 RPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQA 236 Query: 249 ALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQALSERRAQSVVDYLISKGIPADKIS 308 ALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQ LSERRAQSVVDYLISKGIPADKIS Sbjct: 237 ALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKIS 296 Query: 309 ARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA 358 ARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA Sbjct: 297 ARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA 346
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 31.6 bits (71), Expect = 0.005 Identities = 13/48 (27%), Positives = 22/48 (45%) Query: 295 VGVVVTDSQNNIISPAGGTLPLSIPDDADSFARMNVYPVSTTGVPPET 342 + V TD + I+ A T L++ D +S N+Y ++ P T Sbjct: 188 LTVPSTDIEKEILDLAAATERLNLTDALNSNPAGNLYDWRSSNSYPWT 235
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 824 bits (2131), Expect = 0.0 Identities = 416/874 (47%), Positives = 570/874 (65%), Gaps = 19/874 (2%) Query: 3 RTQRQH-SLLSSGGVPSFIGGLVVFVSAAFNAQAETWFDPAFFKDDPSMVADLSRFEKGQ 61 TQ H G + F + A + AE +F+P F DDP VADLSRFE GQ Sbjct: 12 NTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQ 71 Query: 62 KITPGVYRVDIVLNQTIVDTRNVNFVEITPEKGIAACLTTESLDAMGVNTDAFPAFKQLD 121 ++ PG YRVDI LN + TR+V F E+GI CLT L +MG+NT + L Sbjct: 72 ELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLA 131 Query: 122 KQACAPLAEIIPDASVTFNVNKLRLEISVPQIAIKSNARGYVPPERWDEGINALLLGYSF 181 AC PL +I DA+ +V + RL +++PQ + + ARGY+PPE WD GINA LL Y+F Sbjct: 132 DDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNF 191 Query: 182 SGANSIHSSAGSDSGDSYFLNLNSGVNLGPWRLRNNSTWSR-----SSGQTAEWKNLSSY 236 SG + + G+ +LNL SG+N+G WRLR+N+TWS SSG +W++++++ Sbjct: 192 SGNSVQNRIGGNS--HYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTW 249 Query: 237 LQRAVIPLKGELTVGDDYTAGDFFDSVSFRGVQLASDDNMLPDSLKGFAPVVRGIAKSNA 296 L+R +IPL+ LT+GD YT GD FD ++FRG QLASDDNMLPDS +GFAPV+ GIA+ A Sbjct: 250 LERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTA 309 Query: 297 QVTIKQNGYTIYQTYVSPGAFEISDLYSTSSSGDLLVEIKEADGSVNSYSVPFSSVPLLQ 356 QVTIKQNGY IY + V PG F I+D+Y+ +SGDL V IKEADGS ++VP+SSVPLLQ Sbjct: 310 QVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQ 369 Query: 357 RQGRIKYAVTLAKYRTNSNDQQESKFAQATLQWGGPRGTTWYGGGQYAEYYRAAMFGLGF 416 R+G +Y++T +YR+ + Q++ +F Q+TL G P G T YGG Q A+ YRA FG+G Sbjct: 370 REGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGK 429 Query: 417 NLGDFGAISFDATQAKSTLADQSEHKGQSYRFLYAKTLNQLGTNFQLMGYRYSTSGFYTL 476 N+G GA+S D TQA STL D S+H GQS RFLY K+LN+ GTN QL+GYRYSTSG++ Sbjct: 430 NMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNF 489 Query: 477 SDTMYKHMDGY--EFNDGDDEDTPMWSRYYNLFYTKRGKLQVNISQQLGEYGSFYLSGSQ 534 +DT Y M+GY E DG + P ++ YYNL Y KRGKLQ+ ++QQLG + YLSGS Sbjct: 490 ADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSH 549 Query: 535 QTYWHTDQQDRLLQFGYNTQIKDLSLGVSWNYSKSRGQPDADQVFALNFSLPLNLLLPKS 594 QTYW T D Q G NT +D++ +S++ +K+ Q DQ+ ALN ++P + L Sbjct: 550 QTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSD 609 Query: 595 NDSYTRKKNYAWMTSNTSIDNEGHTTQNLGLTETLLDDGNLSYSVQQGYNSEGKTANGS- 653 + S R +A + + S D G T G+ TLL+D NLSYSVQ GY G +GS Sbjct: 610 SKSQWR---HASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGST 666 Query: 654 --ASMDYKGAFADARVGYNYSDNGSQQQLNYALSGSLVAHSQGITLGQSLGETNVLIAAP 711 A+++Y+G + +A +GY++SD+ +QL Y +SG ++AH+ G+TLGQ L +T VL+ AP Sbjct: 667 GYATLNYRGGYGNANIGYSHSDD--IKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAP 724 Query: 712 GAENTRVANSTGLKTDWRGYTVVPYATSYRENRIALDAASLKRNVDLENAVVNVVPTKGA 771 GA++ +V N TG++TDWRGY V+PYAT YRENR+ALD +L NVDL+NAV NVVPT+GA Sbjct: 725 GAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGA 784 Query: 772 LVLAEFNAHAGARVLMKTSKQGMPLRFGAMATLDGAQTISGIIDDDGSLYMSGLPAKGTI 831 +V AEF A G ++LM + PL FGAM T + SGI+ D+G +Y+SG+P G + Sbjct: 785 IVRAEFKARVGIKLLMTLTHNNKPLPFGAMVT-SESSQSSGIVADNGQVYLSGMPLAGKV 843 Query: 832 TVRWGDAPDQICHISYELTEQQINAAITRMDSVC 865 V+WG+ + C +Y+L + +T++ + C Sbjct: 844 QVKWGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 28.1 bits (62), Expect = 0.016 Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 7/67 (10%) Query: 31 SVTFNGKVIAPACTLVAATKDSVVTLPDVSATKLQSNGQVS---GVQTDVPIALEDCDIT 87 ++TF GK+I PACT+ A V D+ L +G V + P +L +T Sbjct: 27 NLTFKGKLIIPACTVQNAE----VNWGDIEIQNLVQSGGNQKDFTVDMNCPYSLGTMKVT 82 Query: 88 VTKNATF 94 +T N Sbjct: 83 ITSNGQT 89
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 30.8 bits (69), Expect = 0.033 Identities = 100/525 (19%), Positives = 168/525 (32%), Gaps = 67/525 (12%) Query: 366 GTLAVSAGGKA---TGVTMTSGGALI---ADSGATV---EGTNASGKFSIDGISGQASGL 416 G +GG G + +GGA + ++ G +A GK + + + L Sbjct: 326 GARVTVSGGSLSAPHGNVIETGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKL 385 Query: 417 LLENG----GSFTVNAGGQAGNTTVGHRGTLTLAAGGSLSGRTQLSKGASMVLNGDVVST 472 L G G T++G + LA+ +G T+ S+ N V T Sbjct: 386 TLTGGADAQGDIVATELPSIPGTSIG-PLDVALASQARWTGATRAVDSLSID-NATWVMT 443 Query: 473 GDIVNAGEIRFDNQTTQDAVLSRAVAKGDAPVTFHKLTTSNLTGQGGTINMRVRLDGSNA 532 + N G +R + + D + F LT + L G G M V D Sbjct: 444 DN-SNVGALRLASDGSVD------FQQPAEAGRFKVLTVNTLAGSG-LFRMNVFAD-LGL 494 Query: 533 SDQLVINGGQATGKTWLAFTNVGNSNLGVATSGQGIRVVDAQNGATTEEGAFALSRPLQA 592 SD+LV+ A+G+ L N G+ S + +V G+ + Sbjct: 495 SDKLVVMQD-ASGQHRLWVRNSGSE----PASANTLLLVQTPLGSAATFTLANKDGKVDI 549 Query: 593 GAFNYTLNRDSDEDWYLRSENAYRAEVPLYASMLTQAMDYDRILAGSRSHQTGVNGENNS 652 G + Y L + + W L A A P + + Sbjct: 550 GTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAA 609 Query: 653 VRLSIQGGHLGHDNNGGIARG-----------ATPESSGSYGFVRLESDLLRTEVA---- 697 ++ G +G + A P++ G++G + L Sbjct: 610 ANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQQLDNRAGRRFD 669 Query: 698 ------------GMSVTAGVYSAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNLVHTSS 745 ++V G + G + D + G D+ +GGY + S Sbjct: 670 QKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYATYI-ADS 728 Query: 746 GLWADIMAQGTRHSMKASSDNND-------FRARGWGWLGSLETGLPFSITDNLMLEPQL 798 G + D + +R +D +R G G SLE G F+ D LEPQ Sbjct: 729 GFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGA--SLEAGRRFTHADGWFLEPQA 786 Query: 799 QYTWQGLSLDDGQDNAGY-VKFGHGSAQHMRAGFRLGSHNDMSFG 842 + + G V+ GS+ R G +G +++ G Sbjct: 787 ELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAGG 831
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.031 Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 5/43 (11%) Query: 5 NILIVG-AGFSGVVIARQLAEQGHKVKIIDQRDHIGGNSYDTR 46 L+ G AGF G ++++L E GH+V ID + + YD Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLN----DYYDVS 40
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.027 Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 6/70 (8%) Query: 503 LHVSTPASEYSQGQ-DLF---NPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNL 558 L V+ E + + LF QR H V+ +T+ + K L N NG+Y YN Sbjct: 926 LQVADKTGEPNHNELTLFDASKAQRDHLNVSLV-GNTVDLGAWKYKLR-NVNGRYDLYNP 983 Query: 559 RGERVKDEKP 568 E+ Sbjct: 984 EVEKRNQTVD 993
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 3e-14 Identities = 22/113 (19%), Positives = 47/113 (41%), Gaps = 2/113 (1%) Query: 9 VMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGL 68 +++ DD +R + Q L G++V + A+ D D+++ D+ M + Sbjct: 6 ILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 69 DTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIR 121 D L +++ +++++ + + GA YL K D L+ I Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 28.0 bits (62), Expect = 0.008 Identities = 12/31 (38%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Query: 34 KHIVLWLGLALACLGLAMVLWLLVL-QNVPV 63 + I+ +L + L C LAM+ W + L N PV Sbjct: 15 RRILFYLLMLLFCQQLAMIFWRIGLPDNAPV 45
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.7 bits (67), Expect = 0.023 Identities = 32/192 (16%), Positives = 58/192 (30%), Gaps = 37/192 (19%) Query: 268 GYGLTEFASTVCAKEADGLADVGSPL----PGREVKIVNDEVWLRAASMAEGYWRNGQRV 323 G+G+ S + A + L ++ + G + I+ E + A + + R+ Sbjct: 40 GHGIERIWSAIGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIY---DQHRL 96 Query: 324 PLVNDEGWYATRDRGEMHNGKLTI-------VGRLDNLFFSGGEGIQPEEVERVIAAHPA 376 W + L I + RL G QP+ V V A Sbjct: 97 TTCVHSNWQLKALQNARLKAPLDIYLKVNSGMNRL---------GFQPDRVLTVWQQLRA 147 Query: 377 VLQVFIVPVADKEFGHRPVAVVEYDQQTVDLDEWVKDKLARFQQPVRWLTLPPELKNGGI 436 + V + + H A + + + +AR +Q L L N Sbjct: 148 MANVGEMTL----MSHFAEA---------EHPDGISGAMARIEQAAEGLECRRSLSNSAA 194 Query: 437 KISRQALK-EWV 447 + +WV Sbjct: 195 TLWHPEAHFDWV 206
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 34.8 bits (80), Expect = 6e-05 Identities = 14/79 (17%), Positives = 31/79 (39%), Gaps = 12/79 (15%) Query: 1 MIEWQDLHHSELSVSQLYALLQLRCAVFV--------VEQNCPYQDIDGDDLTRDNRHIL 52 M+E D++H+ LS ++ L LR F + D + ++ Sbjct: 1 MLEIFDVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYD----NNNTTYLF 56 Query: 53 GWKNDELVAYARILKSDDD 71 G K++ ++ R +++ Sbjct: 57 GIKDNTVICSLRFIETKYP 75
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 36.2 bits (83), Expect = 5e-04 Identities = 20/115 (17%), Positives = 37/115 (32%), Gaps = 5/115 (4%) Query: 22 ESENKESLQQQPSTPTDQQVLAAQHAAIKEAEQRSVAAKATADAKAKALAQQEAQQYSDK 81 ES+ E +Q + T Q A KEA+ A T + +E Q K Sbjct: 1047 ESKTVEKNEQDATETTAQNREVA-----KEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 82 QALQGRLQAAPKYQHAAREKAASQIANPGTARYQQFDDNPVKQVAQNPLATFSLD 136 + + K + ++ + + Q P + A+ T ++ Sbjct: 1102 ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK 1156
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 407 bits (1048), Expect = e-148 Identities = 250/251 (99%), Positives = 250/251 (99%) Query: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 Query: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM Sbjct: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 Query: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADGLYPVLSWLTWPM 180 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMAD LYPVLSWLTWPM Sbjct: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPM 180 Query: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA Sbjct: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 Query: 241 IQDDLKDIDSE 251 IQDDLKDIDSE Sbjct: 241 IQDDLKDIDSE 251
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 91.7 bits (227), Expect = 2e-20 Identities = 115/496 (23%), Positives = 189/496 (38%), Gaps = 62/496 (12%) Query: 2155 TAEAGNFTVGSLTNTGVIRLAGGKTGN-----------TLTVNGDYTGGGTLIINTVLGD 2203 + + + + +N G +RLA + + LTVN G G +N Sbjct: 434 SIDNATWVMTDNSNVGALRLASDGSVDFQQPAEAGRFKVLTVN-TLAGSGLFRMNVFA-- 490 Query: 2204 DTSATDKLIVTGNTSGDTGVVVNNVRGQGAQTADGIEIVHVGGQSDGNFRLQN---RAVA 2260 D +DKL+V + SG + V N G +A+ + +V S F L N + Sbjct: 491 DLGLSDKLVVMQDASGQHRLWVRNS-GSEPASANTLLLVQTPLGSAATFTLANKDGKVDI 549 Query: 2261 GAWEYFLHKGNAGGTDGNWYLR-SELPPEPQPQPQPQPQPQPHPTPDKPVQKVYRPEAGS 2319 G + Y L A +G W L ++ PP P+P PQP PQP P P +P +P AG Sbjct: 550 GTYRYRL----AANGNGQWSLVGAKAPPAPKPAPQPGPQP-PQPPQPQPEAPAPQPPAGR 604 Query: 2320 YIANIAAANTLFNIRMHDREGETYYTDVFTGEKKATSMWMRHIGGHNRWKDSSSQLNTQS 2379 ++ AAAN N +Y + K+ + + G W +Q Sbjct: 605 ELS--AAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAG-GAWGRGFAQRQQLD 661 Query: 2380 NRYVVQLGGSIAQWTDGQD--------RLQLGIMAGYGNEKSSTTSSLSGYKSKGAINGY 2431 NR + +A + G D R LG +AGY T G+ + GY Sbjct: 662 NRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGY 721 Query: 2432 STGLYGTWQQNDGNDNGAYVDTWIQYGWFNN--TVNGEKLAAESWKSR--GFTGSVEAGY 2487 +T + D+G Y+D ++ N V G A K R G S+EAG Sbjct: 722 ATYI---------ADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGR 772 Query: 2488 TFKAGEFTGSQGSHYDWYIQPQSQITWMNVRASEHTEKNGTKVQLSGDGNIQSRLGVRTY 2547 F W+++PQ+++ + NG +V+ G ++ RLG+ Sbjct: 773 RFTH---------ADGWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVG 823 Query: 2548 LKGKSASDDNKAHQFEPFVEVNWIHNTRSWG-VKMDNTALSQDGATNIAEVKTGVQGKLS 2606 + + A Q +P+++ + + G V + A + AE+ G+ L Sbjct: 824 KRIELAGG----RQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALG 879 Query: 2607 DNLNVWGNVGVQAGDK 2622 +++ + G K Sbjct: 880 RGHSLYASYEYSKGPK 895
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 121 bits (306), Expect = 4e-32 Identities = 92/404 (22%), Positives = 167/404 (41%), Gaps = 17/404 (4%) Query: 19 VTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQ 78 + I L + +F +L+ + NV++P I+ WV T+F + +I V G+L+ Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 79 RIGELRLFLLSVTFFSLSSLMCSLS-TNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPP 137 ++G RL L + S++ + + +LI R +QG A L ++ R P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 138 EKRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRE 197 E R A L V + GP +GG I W +L+ +PM I+ L L +E Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKE 192 Query: 198 TETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWES 257 ++ G+ L+ +G+ + ML F +S I +VSV+S + V Sbjct: 193 VRIKG-HFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIR 241 Query: 258 TSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPI 317 +P +D L K+ F IG++ + +G + ++P ++++ + G Sbjct: 242 KVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFP 301 Query: 318 GIMPLLIS-PLIGRYGNKIDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQG 376 G M ++I + G ++ ++ +V + S T F II+ G Sbjct: 302 GTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGG 361 Query: 377 FAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTLSGSVGTSL 420 + ++TI S L + S+ NF LS G ++ Sbjct: 362 LSFTK--TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 78.3 bits (193), Expect = 5e-18 Identities = 61/413 (14%), Positives = 122/413 (29%), Gaps = 96/413 (23%) Query: 13 RKKYFALLAVVLFIAFSGAYAYWSMELEDMISTDDAYVT-GNADPISAQVSGSVTVVNHK 71 R+ ++ F+ + + ++E + + + G + I + V + K Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVLG-QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 72 DTNYVRQGDILVSLDKTDATIALNKA---------------------------------- 97 + VR+GD+L+ L A K Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 98 ------------------KNNLANIVRQTNKLYLQDKQYSAEVASARIQ---YQQSLEDY 136 K + Q + L + AE + + Y+ Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 137 NRRV----PLAKQGVISKE----------TLEHTKDTLISSKAALNAAIQAYKANKALVM 182 R+ L + I+K + S + + I + K LV Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 183 N-------TPLNR-QPQVVEAADATKEAWLALKRTDIKSPVTGYIAQRSVQ-VGETVSPG 233 L + + + + + I++PV+ + Q V G V+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 234 QSLMAVVPARQ-MWVNANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGNA 292 ++LM +VP + V A + + + +GQ+ I + F G +G Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVE------AFPYTRYGYLVGK--- 404 Query: 293 FSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEH----PLRIGLSMTATIDTR 341 + + +V V +S++ L PL G+++TA I T Sbjct: 405 VKNINLDAIEDQRLGLVFNVI--ISIEENCLSTGNKNIPLSSGMAVTAEIKTG 455
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.1 bits (117), Expect = 3e-09 Identities = 22/148 (14%), Positives = 53/148 (35%), Gaps = 31/148 (20%) Query: 4 IIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQV 63 ++ DD + L + ++ + + + + D+V+ DV +P N + Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRIT-SNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYF 123 L ++K + ++++SA+N + AI+A++ G + Sbjct: 66 LPRIKKARPDLPVLVMSAQNT------------------------FMTAIKASEKGAYDY 101 Query: 124 ---PFSLNRFVGSLTSDQQKLDSLSKQE 148 PF L + + L ++ Sbjct: 102 LPKPFDLTE---LIGIIGRALAEPKRRP 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.5 bits (196), Expect = 2e-17 Identities = 31/105 (29%), Positives = 51/105 (48%) Query: 890 SILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKISMQHYDLLITDVNMPNMDGFE 949 +IL+ADD R +L + L+ GYDV ++ I+ DL++TDV MP+ + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 950 LTRKLREQNSSLPIWGLTANAQANEREKGLNCGMNLCLFKPLTLD 994 L ++++ LP+ ++A K G L KP L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>PF06580#Sensor histidine kinase Length = 349 Score = 223 bits (571), Expect = 2e-70 Identities = 60/207 (28%), Positives = 102/207 (49%), Gaps = 11/207 (5%) Query: 342 RAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNIE 401 ++ MA +A+L AL+++INPHF+FNALN I + I +P AR+++ +LS +RY++ Sbjct: 150 DQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLR 209 Query: 402 LKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEV-NCCIPSLLIQPLVENAIV 460 + Q+ + EL + Y+ + +F D+L I+ + + +P +L+Q LVEN I Sbjct: 210 YSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIK 269 Query: 461 HGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHR 520 HGI G + + + V + V +TG E GL NV R Sbjct: 270 HGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE--------STGTGLQNVRER 321 Query: 521 VKLLYGE--GLHIRRLEPGTEIAFYIP 545 +++LYG + + + IP Sbjct: 322 LQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.2 bits (133), Expect = 5e-11 Identities = 21/125 (16%), Positives = 55/125 (44%), Gaps = 6/125 (4%) Query: 2 KVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQHNRVDAIFLDINIPSLDG 61 +++ +D+ + L+ + V + + +++ D + D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALS--RAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 V-LLAQNISQFAHKPFIVFITAWK--EHAVEAFELEAFDYILKPYQESRITGMLQKLEAA 118 LL + P +V ++A A++A E A+DY+ KP+ + + G++ + A Sbjct: 63 FDLLPRIKKARPDLPVLV-MSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 119 WQQQQ 123 +++ Sbjct: 122 PKRRP 126
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 613 bits (1583), Expect = 0.0 Identities = 201/567 (35%), Positives = 330/567 (58%), Gaps = 8/567 (1%) Query: 117 LYGNVLASGVGVGTLTLLQSDSLDSYRAIPA-SAQDSTRLEHSLATLAEQLNQQLRERDG 175 + G +SGV + + ++D + + + +L +L E+L + + Sbjct: 5 ITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEA 64 Query: 176 ----ESKTILSAHLSLIQDDEFAGNIRRLMAEQHQGLGAAIISNMEQVCAKLSASASDYL 231 + I +AHL ++ D E I+ + + A+ + + + ++Y+ Sbjct: 65 SMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYM 124 Query: 232 RERVSDIRDISEQLL-HITWPELKPRNNLVLEKPTILVAEDLTPSQFLSLDLKNLAGMIL 290 +ER +DIRD+S+++L H+ E + + T+++AEDLTPS L+ + + G Sbjct: 125 KERAADIRDVSKRVLGHLIGVETGSLATIA--EETVIIAEDLTPSDTAQLNKQFVKGFAT 182 Query: 291 EKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCGVLAINPNDAVSGYYQV 350 + GRTSH+ I++R+ IP + G G ++D G++ +NP + Y+ Sbjct: 183 DIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEE 242 Query: 351 AQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPGAFANGAEGVGLFRTEMLY 410 + +K++++ A+ + + ++D +++AANIGT + G ANG EG+GL+RTE LY Sbjct: 243 KRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLY 302 Query: 411 MDRDSAPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKSIPYLNIPQEENPFLGYRAVR 470 MDRD P E+EQFEAY++V+ KP++ RT+DIGGDK + YL +P+E NPFLG+RA+R Sbjct: 303 MDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAIR 362 Query: 471 IYPEFAGLFRTQLRAILRAACFGNAQLMIPMVHSLDQILWVKGEIQKAIVELKRDCLRHA 530 + E +FRTQLRA+LRA+ +GN ++M PM+ +L+++ K +Q+ +L + + + Sbjct: 363 LCLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVS 422 Query: 531 ETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMTQYLYAVDRNNPRVSPLYNPITPSF 590 ++I +GIMVE+PS + F EVDFFSIG+ND+ QY A DR N RVS LY P P+ Sbjct: 423 DSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAI 482 Query: 591 LRMLQQIVTTAHQRGKWVGICGELGGESRYLPLLLGLGLDELSMSSPRIPAVKSQLRQLD 650 LR++ ++ AH GKWVG+CGE+ G+ +PLLLGLGLDE SMS+ I +SQL +L Sbjct: 483 LRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKLS 542 Query: 651 SEACRELARQACECRSAQEIEALLTAF 677 E + A++A +A+E+E L+ Sbjct: 543 KEELKPFAQKALMLDTAEEVEQLVKKT 569
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 748 bits (1933), Expect = 0.0 Identities = 276/571 (48%), Positives = 386/571 (67%), Gaps = 2/571 (0%) Query: 1 MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTK 60 I+GI AS G+A KA + E + I++ I V E+E+ + K+ +L IK + Sbjct: 4 KITGIAASSGVAIAKAFIHLEPNVDIEKTSI--TDVSTEIEKLTAALEKSKEELRAIKDQ 61 Query: 61 AGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDD 120 + G +K IF H+++L+D EL I I+++ M A+ A EV + S E +D+ Sbjct: 62 TEASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDN 121 Query: 121 EYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFI 180 EY+KERAAD+RD+ KR+L +++G++ L+ I +E +++A DLTPS+TAQLN + V GF Sbjct: 122 EYMKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFA 181 Query: 181 TDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMR 240 TD GGRTSH++IM+RSLE+PA+VGT VT ++++ D +I+D + V VNPT E + Sbjct: 182 TDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYE 241 Query: 241 AVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFL 300 + +K E AKL P+ T DG VE+ ANIGT +DV+G NG EG+GLYRTEFL Sbjct: 242 EKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFL 301 Query: 301 FMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTMDIGGDKELPYMNFPKEENPFLGWRAI 360 +MDRD LPTEEEQF AYK V + + V++RT+DIGGDKEL Y+ PKE NPFLG+RAI Sbjct: 302 YMDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAI 361 Query: 361 RIAMDRKEILRDQLRAILRASAFGKLRIMFPMIISVEEVRALRKEIEIYKQELRDEGKAF 420 R+ +++++I R QLRA+LRAS +G L++MFPMI ++EE+R + ++ K +L EG Sbjct: 362 RLCLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDV 421 Query: 421 DESIEIGVMVETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDMISHLYQPMSPS 480 +SIE+G+MVE P+ A A AKEVDFFSIGTNDL QYT+A DR N+ +S+LYQP P+ Sbjct: 422 SDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPA 481 Query: 481 VLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNT 540 +L L+ VI A+H+EGKW GMCGE+AGDE A LLLG+GLDEFSMSA SI + + Sbjct: 482 ILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKL 541 Query: 541 NFEDAKVLAEQALAQPTTDELMTLVNKFIEE 571 + E+ K A++AL T +E+ LV K + Sbjct: 542 SKEELKPFAQKALMLDTAEEVEQLVKKTYLK 572
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.3 bits (78), Expect = 7e-04 Identities = 11/33 (33%), Positives = 16/33 (48%) Query: 30 MVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFH 62 V L G G GK+TL+ + GL+ + H Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG 630
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.5 bits (71), Expect = 6e-04 Identities = 15/102 (14%), Positives = 38/102 (37%), Gaps = 4/102 (3%) Query: 24 LRPWNDPEMDIERKMNHDVSLFLVAEVNGEVVG--TVMGGYDGHRGSAYYLGVHPEFRGR 81 + + D +MD+ + FL + +G + ++G + V ++R + Sbjct: 47 FKQYEDDDMDVSYVEEEGKAAFL-YYLENNCIGRIKIRSNWNG-YALIEDIAVAKDYRKK 104 Query: 82 GIANALLNRLEKKLIARGCPKIQINVPEDNDMVLGMYERLGY 123 G+ ALL++ + + + + N Y + + Sbjct: 105 GVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 50.1 bits (120), Expect = 3e-09 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Query: 63 VRDGIVWDFFGAVTIVRRHLD-TLEQQFGRRFSHAATSFPPGTDP---RISINVLESAGL 118 ++DG++ DFF +++ + F R P G R + AG Sbjct: 76 MKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGA 135 Query: 119 EVSHVLDEPTAVA---DLLQLDNAG--VVDIGGGTTGIAIVKKGKVTYSADEATGG 169 +++EP A A L + G VVDIGGGTT +A++ V YS+ GG Sbjct: 136 REVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGG 191
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.1 bits (62), Expect = 0.024 Identities = 19/124 (15%), Positives = 40/124 (32%), Gaps = 6/124 (4%) Query: 34 QQGKNEEQRQHDEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEATA 93 Q + ++ + + + E+ Q Q K AT +KA+ + + Sbjct: 1064 QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET-EKTQEV 1122 Query: 94 DKKRDQSYEDELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANR 153 K Q + +S +Q Q + + V I + D Q + + Sbjct: 1123 PKVTSQVSPKQEQSETVQPQAEPARENDPTVN-----IKEPQSQTNTTADTEQPAKETSS 1177 Query: 154 NMTE 157 N+ + Sbjct: 1178 NVEQ 1181
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 28.5 bits (63), Expect = 0.025 Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 21/120 (17%) Query: 127 GNPLSSQEVLEGGESLILSE-----VAEPPAQMIDSLTTLFKTIKPVKRAFICSIKENEE 181 G+ ++SQE+L +S++ + E + ++ +F+TI P+ + F +K E+ Sbjct: 217 GDTITSQELLAQAQSILNKNHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYRVKNREQ 276 Query: 182 A-QPNLLIGIEADGDIEEIIQAAGSVATDTIPGDEPIDICQVKKGEKGISHFITEHIVPF 240 A + N G+ + + ++I V +KKGEK F H+ F Sbjct: 277 AYRINKKSGLNEEINNTDLISEKYYV---------------LKKGEKPYDPFDRSHLKLF 321
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 114 bits (288), Expect = 5e-30 Identities = 81/371 (21%), Positives = 144/371 (38%), Gaps = 74/371 (19%) Query: 23 GIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHS-------VGYDARTNAA 75 IDLGT N+L+ G + +E PSVV +Q VG+DA+ Sbjct: 14 SIDLGTANTLIYVKGQG----IVLNE-----PSVVAIRQDRAGSPKSVAAVGHDAK-QML 63 Query: 76 LDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILK 135 T I++++ + +AD V+ +L+ Sbjct: 64 GRTPGNIAAIRPMKDGVIADF-------------------------------FVTEKMLQ 92 Query: 136 ALAARATEALAGE-LDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYG 194 + V++ VP +R+ +++A+ AG + L+ EP AAAI G Sbjct: 93 HFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAG 152 Query: 195 LDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAG 254 L + V D+GGGT +++++ L+ V +GGD FD + +Y+R G Sbjct: 153 LPVSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYG 207 Query: 255 --IPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAG---WQG-----EISREQFNELI 304 I + + R++ E+ A + + V G +G ++ + E + Sbjct: 208 SLIGEATAERIKHEI-------GSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEAL 260 Query: 305 APLVKRTLLACRRALKDAGVE-ADEVLE--VVMVGGSTRVPLVRERVGEFFGRPPLTSID 361 + + A AL+ E A ++ E +V+ GG + + + E G P + + D Sbjct: 261 QEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED 320 Query: 362 PDKVVAIGAAI 372 P VA G Sbjct: 321 PLTCVARGGGK 331
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 25.9 bits (57), Expect = 0.033 Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 11/87 (12%) Query: 4 KTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVSKIRV--GMTQQQVAYALGT 61 K + AVL + AG LER ++ Q + + + VS+ + GMT ++ A Sbjct: 69 KVV-LCGAVLARVDAGDEQLERKIH---YRQQDLVDYSPVSEKHLADGMTVGELCAA--A 122 Query: 62 PLMSDPFGTNTWFYVFRQQPGHEGVTQ 88 MSD N + G G+T Sbjct: 123 ITMSDNSAANL---LLATVGGPAGLTA 146
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 241 bits (616), Expect = 7e-68 Identities = 219/883 (24%), Positives = 351/883 (39%), Gaps = 89/883 (10%) Query: 763 NDGGTLDVREKGSATGIQQSSQGAL-VATTRATRVTGTRADGVAFSIEQGAANNILLTNG 821 N+ + E+ IQ S G + A+ +V+G +A G+ + A + NG Sbjct: 37 NNQSIVKTGERQHGIHIQGSDPGGVRTASGTTIKVSGRQAQGILL---ENPAAELQFRNG 93 Query: 822 GVLT----VESDTSSAKTQVNAGGREIVKTKATATGTTLTGGEQ----IVEGVANETTIN 873 V + + V ++V AT T + V G + +I Sbjct: 94 SVTSSGQLSDDGIRRFLGTVTVKAGKLVADHATLANVGDTWDDDGIALYVAGEQAQASIA 153 Query: 874 DGGIQTVS-------ANGEAVKTTINEGGTLTVNDNGKATDIIQNSGAALQTSTANGIEI 926 D +Q AN ++ I +GG + + S L+ + + Sbjct: 154 DSTLQGAGGVQIERGANVTVQRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPA 213 Query: 927 SGTHQY------------GTFSIAGNLATNALLENGGNLLVLAGTEARDSTVG------- 967 SG G G A A ++ L A D+ G Sbjct: 214 SGAPAAVSVLGASELTLDGGHITGGRAAGVAAMQGAVVHLQRATIRRGDAPAGGAVPGGA 273 Query: 968 -KGGAMQNLGQDSATKVNSGGQYTL---GRSKDEFQALARAEDLQVA-----GGTAIVYA 1018 GGA+ G Y + G S + Q++ A +L A G V Sbjct: 274 VPGGAVPGGFGPGGFGPVLDGWYGVDVSGSSVELAQSIVEAPELGAAIRVGRGARVTVSG 333 Query: 1019 GTLA--DASVSGATGSLSLMTPRDNVTPVKLEGAIRITDSATLTIGNGVDTTLTDLTAA- 1075 G+L+ +V G+ P+ + L+ A L LT A Sbjct: 334 GSLSAPHGNVIETGGARRFA-PQAAPLSITLQAGAHAQGKALLYRVLPEPVKLTLTGGAD 392 Query: 1076 SRGSVWLNSNNSCAGTSNCEYR---------------VNSLLLNDG-----------DVY 1109 ++G + S GTS V+SL +++ + Sbjct: 393 AQGDIVATELPSIPGTSIGPLDVALASQARWTGATRAVDSLSIDNATWVMTDNSNVGALR 452 Query: 1110 LSAQTA---APATTNGIYNTLTTSELSGSGNFYLHTNVAGSRGDQLVVNNNATGNFKIFV 1166 L++ + G + LT + L+GSG F ++ D+LVV +A+G +++V Sbjct: 453 LASDGSVDFQQPAEAGRFKVLTVNTLAGSGLFRMNVFADLGLSDKLVVMQDASGQHRLWV 512 Query: 1167 QDTGVSPQSDDAMTLVKT-GGGDASFTLGNTGGFVDLGTYEYVLKSDGNSNWNLTNDVKP 1225 +++G P S + + LV+T G A+FTL N G VD+GTY Y L ++GN W+L P Sbjct: 513 RNSGSEPASANTLLLVQTPLGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAP 572 Query: 1226 NPDPNPNPKPDPKPDPKPDPKPDPTPDPTPTPVPEKRITPSTAAVLNMA--ATLPLVFDA 1283 P P P P+P P+P P P+P+ P P P + ++ + A +N ++ A Sbjct: 573 -PAPKPAPQPGPQPPQPPQPQPEA---PAPQPPAGRELSAAANAAVNTGGVGLASTLWYA 628 Query: 1284 ELNSIRERLNIMKASPHNNNVWGTTYNTRNNVTTDAGAGFEQTLTGMTVGIDSRNDIPEG 1343 E N++ +RL ++ +P WG + R + AG F+Q + G +G D + G Sbjct: 629 ESNALSKRLGELRLNPDAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVAVAGG 688 Query: 1344 IATLGAFMGYSHSHIGFDRGGHGSVGSYSLGGYASWEHESGFYLDGIVKLNRFESNVAGK 1403 LG GY+ GF G G S +GGYA++ +SGFYLD ++ +R E++ Sbjct: 689 RWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYATYIADSGFYLDATLRASRLENDFKVA 748 Query: 1404 MSSGGAANGSYRSNGLGGHIETGMRFT-DGNWNLTPYASLTGFTADNPEYHLSNGMESKS 1462 S G A G YR++G+G +E G RFT W L P A L F A Y +NG+ + Sbjct: 749 GSDGYAVKGKYRTHGVGASLEAGRRFTHADGWFLEPQAELAVFRAGGGAYRAANGLRVRD 808 Query: 1463 VDTRSIYRELGATLSYNMRLGNGMEVEPWLKAAVRKEFVDDNRVKVNNDGNFVNDLSGRR 1522 S+ LG + + L G +V+P++KA+V +EF V N + +L G R Sbjct: 809 EGGSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAH-RTELRGTR 867 Query: 1523 GIYQAGIKASFSSSLSGNLGVGYSHGAGVESPWNAVAGVNWSF 1565 G+ A+ S YS G + PW AG +S+ Sbjct: 868 AELGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 80.9 bits (199), Expect = 3e-20 Identities = 67/257 (26%), Positives = 120/257 (46%), Gaps = 7/257 (2%) Query: 3 QVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQEINAEYGEGMAYGFGADA 62 ++A + G Q +G + LA++G +A VD +K V + AE A F AD Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE--ARHAEAFPADV 66 Query: 63 TSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQLGDFDRSLQVNLVGYFLCARE 122 ++ ++ ++ G +D+LV AG+ + I +++ + VN G F +R Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 123 FSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHSL 182 S+ M D G I+ + S V + Y+++K V T+ L L+LAEY I + + Sbjct: 127 VSKYM-MDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 183 MLGNLLKSPMFQSL-LPQYATKLGIKPEQVEQYYIDKVPLKRGCDYQDVLNMLLFYASPK 241 G+ ++ M SL + + IK +E + +PLK+ D+ + +LF S + Sbjct: 186 SPGS-TETDMQWSLWADENGAEQVIKGS-LETFKTG-IPLKKLAKPSDIADAVLFLVSGQ 242 Query: 242 ASYCTGQSINVTGGQVM 258 A + T ++ V GG + Sbjct: 243 AGHITMHNLCVDGGATL 259
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 28.7 bits (64), Expect = 0.014 Identities = 20/105 (19%), Positives = 35/105 (33%), Gaps = 17/105 (16%) Query: 1 MKPRQRQAAILEYLQKQGKCSVEEL-----AQYFDTTGTTIRKDLVILEHAGTVIRTYGG 55 M QR I E + + +EL ++ T T+ +D+ E + T G Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIK--ELHLVKVPTNNG 58 Query: 56 ---VVLNKEESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIIL 97 L ++ P+ K + +A V I+L Sbjct: 59 SYKYSLPADQRFNPLS-------KLKRSLMDAFVKIDSASHLIVL 96
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 370 bits (951), Expect = e-126 Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 33/388 (8%) Query: 149 IAALAAGALS----------NALLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLK 198 I A GA +I + ++ ++ ++G S M ++ Sbjct: 91 IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY 150 Query: 199 KEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFG 258 + + + +DL ++I+GE+GTGKELVA+A+H+ R P V +N AA+P + ESELFG Sbjct: 151 RVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG 210 Query: 259 HVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLR 318 H KGAFTGA + +G+FE A+ GTLFLDEIG++ + Q +LLRVLQ G+ VG +R Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIR 270 Query: 319 VDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRL 378 DVR++AATN+DL++ + G FR DL++RL+V PL +PPLR+R +D+ L +F +Q Sbjct: 271 SDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE- 329 Query: 379 RLGLSRVVLSARARNLLQHYNFPGNVRELEHAIHRAVVLARATRSGDEVIL-----EAQH 433 + GL A L++ + +PGNVRELE+ + R L E+I E Sbjct: 330 KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPD 389 Query: 434 FAFPEVTLPPPEAAAVPIVKQNLR-----------------EATEAFQRETIRQALAQNH 476 + + V++N+R + I AL Sbjct: 390 SPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATR 449 Query: 477 HNWAASARMLETDVANLHRLAKRLGLKD 504 N +A +L + L + + LG+ Sbjct: 450 GNQIKAADLLGLNRNTLRKKIRELGVSV 477
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 25.6 bits (56), Expect = 0.010 Identities = 10/42 (23%), Positives = 21/42 (50%) Query: 5 VIVTSVDDIVFPALQNLISLNNSKLKTGMICECIGALTVIAG 46 +++ + I PALQ ++S + + G + + ALT + Sbjct: 307 MVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTS 348
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 29.6 bits (66), Expect = 0.012 Identities = 19/103 (18%), Positives = 34/103 (33%), Gaps = 8/103 (7%) Query: 6 LIACKGMKMMTTMLEVAKRAGVSKATVSRVLSG-----NGYVSQETKDRVFQAVEESGYR 60 L + +G+ T++ E+AK AGV++ + + + +E Sbjct: 23 LFSQQGVSS-TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKF 81 Query: 61 PNLLARNLSAKSTQTLGLVVTNTLYHGIYFSELLFHAARMAEE 103 P L L VT + E++FH E Sbjct: 82 PGDPLSVLREILIHVLESTVTEERRRLLM--EIIFHKCEFVGE 122
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 27.0 bits (59), Expect = 0.012 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 8/75 (10%) Query: 12 IDGNQAKVD--VCGIQRDVDLTLVGSCDENGQPRVGQWVLVHVGFAMSVINEAEARDTLD 69 I GNQ + D G+ D L ++NG+P G W+ + + F + ++ ++ D + Sbjct: 171 IIGNQIRTDQKFMGV-FDESLKERQEAEKNGEPTGGDWLDIFLSF---IFDKKQSSDVKE 226 Query: 70 ALQN--MFDVEPDVG 82 A+ + V+PD+ Sbjct: 227 AINQEPVPHVQPDIA 241
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 389 bits (1000), Expect = e-131 Identities = 140/373 (37%), Positives = 204/373 (54%), Gaps = 39/373 (10%) Query: 350 YQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVLKQVEMVAQSDSTVLILG 409 E+ + R + E +L + + ++GRS AM + + + + Q+D T++I G Sbjct: 108 LTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITG 167 Query: 410 ETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDLFGHERGAFTGASAQRIGRF 469 E+GTGKEL+ARA+H+ R N V +N AA+P L+ES+LFGHE+GAFTGA + GRF Sbjct: 168 ESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRF 227 Query: 470 ELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSNKIIQTDVRLIAATNRDLKKMV 529 E A+ +LFLDE+GDMP++ Q +LLRVLQ+ E+ +G I++DVR++AATN+DLK+ + Sbjct: 228 EQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSI 287 Query: 530 ADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLAKAFTFKIARRLGRNIDSIPAETLRIL 589 FR DLYYRLNV P+ LPPLR+R EDIP L + F + A + G ++ E L ++ Sbjct: 288 NQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFV-QQAEKEGLDVKRFDQEALELM 346 Query: 590 SNMEWPGNVRELENVIERAVLLTRGNVLQLSL---------------------PDIALPE 628 WPGNVRELEN++ R L +V+ + +++ + Sbjct: 347 KAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQ 406 Query: 629 PETPPAATVVAQEG--------------EDEYQLIVRVLKETNGVVAGPKGAAQRLGLKR 674 A G E EY LI+ L T G AA LGL R Sbjct: 407 AVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQI---KAADLLGLNR 463 Query: 675 TTLLSRMKRLGID 687 TL +++ LG+ Sbjct: 464 NTLRKKIRELGVS 476
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 27.4 bits (61), Expect = 0.027 Identities = 16/138 (11%), Positives = 39/138 (28%), Gaps = 28/138 (20%) Query: 35 NDEVELTLAGGAKLVAIV--------------THSSQQALGLAKGKEAIAL----IKAPW 76 N + A A++ ++V + L +EAI L K P Sbjct: 17 NLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGFALLNLEEAITLRERGWKGPI 76 Query: 77 VTL--ATEDCGLKFSARNQFAGSVSTI--------TEGAVNATVHIKTDAGFEIVAVVTN 126 + L L+ +++ V + +++K ++G + + Sbjct: 77 LMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPD 136 Query: 127 ESQDEMKLTTGSRVIALI 144 + + + Sbjct: 137 RVLTVWQQLRAMANVGEM 154
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.020 Identities = 16/84 (19%), Positives = 36/84 (42%), Gaps = 12/84 (14%) Query: 292 IIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLVREQQEVKAGQKIATMGS 351 I+ATA+G++ ++G + IK ++ ++V+E + V+ G + + + Sbjct: 82 IVATANGKLTHSGRSK-------EIKP---IENSIV--KEIIVKEGESVRKGDVLLKLTA 129 Query: 352 TGTSSTRLHFEIRYKGKSVNPLRY 375 G + L + + RY Sbjct: 130 LGAEADTLKTQSSLLQARLEQTRY 153
>PF07675#Cleaved Adhesin Length = 1358 Score = 30.8 bits (69), Expect = 0.020 Identities = 20/92 (21%), Positives = 39/92 (42%), Gaps = 12/92 (13%) Query: 206 ILGQTYLPRKFKTTVVIP---PQND--IDLHANDMNFVAIAENGKLVGFNLLVGGGLSIE 260 ++ +P+ T +P PQN + A+ ++VAI+++G L G + G++ Sbjct: 240 VMPYRAMPKT--NTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATV 297 Query: 261 HGNK-----KTYARTASEFGYLPLEHTLAVAE 287 + K Y + YLP+ + E Sbjct: 298 NMTKQITENGNYDVVITRSNYLPVIKQIQAGE 329
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 35.2 bits (81), Expect = 5e-04 Identities = 45/314 (14%), Positives = 112/314 (35%), Gaps = 36/314 (11%) Query: 69 LGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTP-EHLIGLRILIGIGLGGDYSV 127 +G+ V G +SD +G +++ F ++ S + F + LI R + G G ++ Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL 123 Query: 128 GHTLLAEFSPRRHRGILLGAFSVVWT----VGYVLASIAGHHFISENPEAWRWLLASAAL 183 ++A + P+ +RG G + VG + + H+ W +LL + Sbjct: 124 VMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------HWSYLLLIPMI 177 Query: 184 PALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYLGPHVLLGDEVAAATHKHIKTLF-- 241 + + L + R +G F I+ +L + + + L Sbjct: 178 TIITVPFLMKLLKKEVR---IKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL 234 Query: 242 -SSRYWRRTA--------FNSVFFVCLVIPWFVIYT----WLPTIAQTIGLEDALTASLM 288 ++ R+ ++ F+ V+ +I+ ++ + + L+ + + Sbjct: 235 IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEI 294 Query: 289 LNALLIVGALLGLV-------LTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLF 341 + ++ G + ++ L L L+ + + + L +S + + Sbjct: 295 GSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTII 354 Query: 342 VLFSTTISAVSNLV 355 ++F + + V Sbjct: 355 IVFVLGGLSFTKTV 368
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 106 bits (265), Expect = 1e-29 Identities = 72/257 (28%), Positives = 116/257 (45%), Gaps = 11/257 (4%) Query: 11 MDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIEK-QGVEVD 69 M+ ++GK A +TG G+G+A A LA GA++ + + E K + + Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 70 FMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAA 129 D+ A +I A G +DILVN AG+ + + +W+ VN T Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 130 FELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNI 189 F S +K M+ ++SG I+ + S + + AY+++K A FTK EL +YNI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 190 QVNGIAPGYYATDI--TLATRSNPETNQRVLDH-------IPANRWGDTQDLMGTAIFLA 240 + N ++PG TD+ +L N Q + IP + D+ +FL Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAE-QVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 241 SPASNYVNGHLLVVDGG 257 S + ++ H L VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.0 bits (65), Expect = 0.034 Identities = 21/103 (20%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Query: 48 GLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVA 107 G++++ + + G ++D+F R ++ ++ + +MAT P LWV+ ++ Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 108 FAITTILMLWSVSIKAASLLGD---HSEQGKIMGWMEGLRGVG 147 IT + A + + D E+ + G+M G G Sbjct: 106 AGITG-----ATGAVAGAYIADITDGDERARHFGFMSACFGFG 143
>cloacin#Cloacin signature. Length = 551 Score = 38.5 bits (89), Expect = 2e-05 Identities = 19/39 (48%), Positives = 20/39 (51%), Gaps = 1/39 (2%) Query: 253 PQKKASGRSYHSDSGGSGGGSSGGGFNGGGGSSGGGGAS 291 P SG H GGSG G+ GG N GGGS GG S Sbjct: 45 PWGGGSGSGIH-WGGGSGHGNGGGNGNSGGGSGTGGNLS 82 Score = 33.5 bits (76), Expect = 8e-04 Identities = 16/29 (55%), Positives = 18/29 (62%) Query: 264 SDSGGSGGGSSGGGFNGGGGSSGGGGASG 292 S SG GG SG G GG G+SGGG +G Sbjct: 50 SGSGIHWGGGSGHGNGGGNGNSGGGSGTG 78 Score = 31.2 bits (70), Expect = 0.005 Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 3/39 (7%) Query: 257 ASGRSYHSDSGGSGGGSSGG---GFNGGGGSSGGGGASG 292 + G + S++ GGGS G G G G+ GG G SG Sbjct: 34 SDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSG 72 Score = 31.2 bits (70), Expect = 0.005 Identities = 10/25 (40%), Positives = 11/25 (44%) Query: 268 GSGGGSSGGGFNGGGGSSGGGGASG 292 G G G GG NG G G G + Sbjct: 57 GGGSGHGNGGGNGNSGGGSGTGGNL 81 Score = 30.5 bits (68), Expect = 0.009 Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 1/29 (3%) Query: 263 HSDSGGSGGGSSGGGFNGGGGSSGGGGAS 291 HS SG GG +G G GGG S G G +S Sbjct: 14 HSTSGNINGGPTGLGV-GGGASDGSGWSS 41 Score = 30.5 bits (68), Expect = 0.010 Identities = 12/30 (40%), Positives = 12/30 (40%) Query: 263 HSDSGGSGGGSSGGGFNGGGGSSGGGGASG 292 GGGS G G G S GG G G Sbjct: 50 SGSGIHWGGGSGHGNGGGNGNSGGGSGTGG 79 Score = 29.3 bits (65), Expect = 0.021 Identities = 12/26 (46%), Positives = 14/26 (53%) Query: 267 GGSGGGSSGGGFNGGGGSSGGGGASG 292 GGSG G GG +G G G G + G Sbjct: 48 GGSGSGIHWGGGSGHGNGGGNGNSGG 73
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.038 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 9/132 (6%) Query: 211 GYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLA-----GEGN 265 P L N + A+ +E K YE+GK I+L + + ++ + + Sbjct: 147 RETPKLIINIKDYAINSEQSKEVYYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSDSS 206 Query: 266 KAFTSEEFTHFLEELTKQYPIVSIEDGLDESDW---DGFAYQTKVLG-DKIQLVGDDLFV 321 S++F LE K I I++ L E F+Y ++L D+F Sbjct: 207 DLLFSQKFKEKLELNNKSIDINFIKENLTEFQHAFSLAFSYYFAPDHRTVLELYAPDMFE 266 Query: 322 TNTKILKEGIEK 333 K+ K G EK Sbjct: 267 YMNKLEKGGFEK 278
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.0 bits (65), Expect = 0.036 Identities = 36/239 (15%), Positives = 76/239 (31%), Gaps = 18/239 (7%) Query: 158 SHMQLYIGAALSAVLVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFS 217 H + AAL+ + L L + + L+ A F+ R Sbjct: 159 PHAPFFAAAALNGLNFLTGCFLLPES---HKGERRPLRREALNPLASFRWARGMTVVAAL 215 Query: 218 MLLGAELQITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLF-ILTIPFFLS 276 M + +Q+ F +D + + I ++ I +L + + Sbjct: 216 MAVFFIMQLVGQVPAALWVIFGEDRFHWDATTI---GISLAAFGILHSLAQAMITGPVAA 272 Query: 277 RYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVEKE 336 R G + +M+ ++A + L A+ + ++V + + + ++ Sbjct: 273 RLGERRALMLGMIADGTGYILLAF-----ATRGWMAFPIMVLLASGGIGMPALQAMLSRQ 327 Query: 337 VSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQ-TVWLIFAGYSVVL 394 V + QG +T+ L IV + IT W W+ A ++ Sbjct: 328 VDEERQGQLQGSLAALTS-----LTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLC 381
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.8 bits (106), Expect = 4e-07 Identities = 63/306 (20%), Positives = 106/306 (34%), Gaps = 27/306 (8%) Query: 20 FLYFFIMATCFPFLPVWLSDVV--GLSKTDTGIVFSCLSLFAISFQPLLGVISDRLGLKK 77 L + P LP L D+V GI+ + +L + P+LG +SDR G + Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 78 NLIWSISLLLVFFAPFFLYVFAPLLRFNIWAGALTGGVFIGFVFSAGAGAIEAYIERVSR 137 L+ S L + + AP L ++ G + G+ G + I + R Sbjct: 75 VLLVS---LAGAAVDYAIMATAPFLWV-LYIGRIVAGI-TGATGAVAGAYIADITDGDER 129 Query: 138 SRGFEYGKARMFGCLGWALCA--AMAGMLFNVDPSLVFWMGSGSALLLLLL-LFLARPST 194 +R F + M C G+ + A + G++ P F+ + L L FL S Sbjct: 130 ARHFGF----MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESH 185 Query: 195 SQTAMVMNTLGANSSLISTRMVFSLFRMRQMWMFVLYTIGVACVYDVFDQQFATFFRSFF 254 + N + FR + V + V + + Q A + F Sbjct: 186 KGERRPLRREALNP--------LASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG 237 Query: 255 -DTPQAGIKAFGFATTAGEICNAII-MFCTPWIIHRIGAKNTLLVAGGIMTIRITGSAFA 312 D G + A I +++ T + R+G + L++ M TG Sbjct: 238 EDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLG---MIADGTGYILL 294 Query: 313 TTATEV 318 AT Sbjct: 295 AFATRG 300
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 31.2 bits (70), Expect = 0.010 Identities = 34/155 (21%), Positives = 65/155 (41%), Gaps = 15/155 (9%) Query: 4 SLAHENARLRALLQTQQDTIRQMAEYNRLLSQRVAAYASEINRLKALVAKLQRMQFGKSS 63 + A A AL Q +D + + +N + A N A+ A+ +R++ K+ Sbjct: 79 AQAKAKANRDALTQRLKDIVNEALRHNASRTPSATELAHANN--AAMQAEDERLRLAKAE 136 Query: 64 EKLR---AKTERQIQEAQERISALQEEMAETLGEQYDPVLPSAALRQSSACKQLPASLPR 120 EK R E+ QEA++R ++ E AET L+ + A ++ A+L Sbjct: 137 EKARKEAEAAEKAFQEAEQRRKEIEREKAET----------ERQLKLAEAEEKRLAALSE 186 Query: 121 ETRVIRPEEECCPACGGELSSLGCDVSEQLELISS 155 E + + ++ A E+ + ++ +SS Sbjct: 187 EAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSS 221
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 27.4 bits (60), Expect = 0.018 Identities = 15/61 (24%), Positives = 24/61 (39%), Gaps = 5/61 (8%) Query: 74 VELLPVEITPDEQKEPVAAIAPSLSTSTQTRVSASSCKVEFRHGNMTLENPSPELLTVLI 133 VE P +PDE P+ P+L T+ + ++L N +LT+ Sbjct: 40 VEGGPTVPSPDEPGLPLPGPGPALPTNGAIPIPEPGTAPA-----VSLMNMDGSVLTMWS 94 Query: 134 R 134 R Sbjct: 95 R 95
>adhesinb#Adhesin B signature. Length = 310 Score = 334 bits (858), Expect = e-117 Identities = 93/298 (31%), Positives = 164/298 (55%), Gaps = 7/298 (2%) Query: 7 LTMLLGFLALTCSIAFQASATEKFKVITTFTIIADMAKNVAGDVAEVSSITKPGAEIHEY 66 L +G A + + + + K V+ T +IIAD+ KN+AGD + SI G + HEY Sbjct: 11 LLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSIVPVGQDPHEY 70 Query: 67 QPTPGDIKRAQGAQLILANGMNLEL----WFQRFYQHLNGVPE---VIVSSGVTPVGITE 119 +P P D+K+ A LI NG+NLE WF + ++ VS GV + + Sbjct: 71 EPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVSEGVDVIYLEG 130 Query: 120 GPYEGKPNPHAWMSPDNALIYVDNIRDALIKYDPANAKTYQRNADTYKAKITQTLAPLRK 179 +GK +PHAW++ +N +IY NI L + DPAN +TY++N Y K++ ++ Sbjct: 131 QSEKGKEDPHAWLNLENGIIYAQNIAKRLSEKDPANKETYEKNLKAYVEKLSALDKEAKE 190 Query: 180 QIAELPENKRWMVTSEGAFSYLARDLGLKELYLWPINADQQGTPQQVRKVVDIVKKNNIP 239 + +P K+ +VTSEG F Y ++ + Y+W IN +++GTP Q++ +V+ ++K +P Sbjct: 191 KFNNIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEKLRKTKVP 250 Query: 240 AVFSESTVSDKPARQVARETGAHYGGVLYVDSLSTENGPVPTYIDLLKVTTSTLVQGI 297 ++F ES+V D+P + V+++T ++ DS++ + +Y ++K + +G+ Sbjct: 251 SLFVESSVDDRPMKTVSKDTNIPIYAKIFTDSVAEKGEEGDSYYSMMKYNLEKIAEGL 308
>PF04183#IucA / IucC family Length = 580 Score = 823 bits (2128), Expect = 0.0 Identities = 577/580 (99%), Positives = 580/580 (100%) Query: 1 MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLWI 60 MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLWI Sbjct: 1 MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLWI 60 Query: 61 DAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYSTLLGDLQLLKARRGLSASD 120 DAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLY+TLLGDLQLLKARRGLSASD Sbjct: 61 DAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASD 120 Query: 121 LINLSADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRC 180 LINL+ADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRC Sbjct: 121 LINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRC 180 Query: 181 DNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEG 240 DNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEG Sbjct: 181 DNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEG 240 Query: 241 RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASR 300 RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASR Sbjct: 241 RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASR 300 Query: 301 WLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLK 360 WLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLK Sbjct: 301 WLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLK 360 Query: 361 PDESPVLMATLMECDENDQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALI 420 PDESPVLMATLMECDEN+QPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALI Sbjct: 361 PDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALI 420 Query: 421 AHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDL 480 AHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDL Sbjct: 421 AHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDL 480 Query: 481 QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFSLFRPQIIR 540 QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFSLFRPQIIR Sbjct: 481 QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFSLFRPQIIR 540 Query: 541 VVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLWLVTQEYES 580 VVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLWLVTQEYES Sbjct: 541 VVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLWLVTQEYES 580
>PF04183#IucA / IucC family Length = 580 Score = 332 bits (853), Expect = e-109 Identities = 110/474 (23%), Positives = 181/474 (38%), Gaps = 45/474 (9%) Query: 37 ELIIPLDEQKSLHFRVAYFSPTQHHRF-----AFPAHLVTASGSYPVDFTTLSRLIIDKL 91 E + + Q + + P RF + + A D L++ ++ +L Sbjct: 24 EQVFHAESQGDDRYCIN--LPGAQWRFIAERGIWGWLWIDAQTLRCADEPVLAQTLLMQL 81 Query: 92 RHQLFLPVPLCETFHQRVLESYAHTQQTIDARHDWAILREKALNFGEAEQALLTGHAFHP 151 + L + Q + + Q + AR + LN + Q LL+GH Sbjct: 82 KQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLNA-DRLQCLLSGHPKFV 140 Query: 152 APKSHEPFNRQEAERYLPDMAPHFPLRWFSVDKTQIAGES-LHLNLQQRLTRFAAENAPQ 210 K + ++ ERY P+ A F L W +V + + +++ Q LT A PQ Sbjct: 141 FNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLT---AAMDPQ 197 Query: 211 LLNELS--------DNQWLF-PLHPWQGEYLLQQVWCQALFAKGLIRDLGEAGTSWLPTT 261 S D+ WL P+HPWQ + + + A FA+G + LGE G WL Sbjct: 198 EFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFI-ADFAEGRMVSLGEFGDQWLAQQ 256 Query: 262 SSRSLYCATSRD--MIKFSLSVRLTNSVRTLSVKEVERGMRLARLAQ----TDGWQMLQA 315 S R+L A+ R IK L++ T+ R + + + G +R Q TD + Sbjct: 257 SLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSG 316 Query: 316 ----RFPTFRVMQEDGWAGLRDLNGNIMQESLFSLRENLLLEQPQSQTNVLVSLTQAAPD 371 P + +G+A L + REN ++ VL++ + Sbjct: 317 AVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDE 376 Query: 372 GGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILV 431 L + + DR G+ A W+ + V+ PL+ YG+ L+AH QNI + Sbjct: 377 NNQPLAGAYI----DRSGLD----AETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITL 428 Query: 432 QMLGDLPVGFIYRDCQGSAFMPHATEWLDTIDEAQAENIFTREQLLRYFPYYLL 485 M +P + +D QG M E +D E R+ R YL+ Sbjct: 429 AMKEGVPQRVLLKDFQGD--MRLVKEEFPEMDSLPQE---VRDVTSRLSADYLI 477
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.0 bits (109), Expect = 2e-07 Identities = 84/380 (22%), Positives = 135/380 (35%), Gaps = 49/380 (12%) Query: 20 FSAGLLGIGQNGLLVVLPVLVIQTNLSLSV---WAALLMLGSMLFLPSSPWWGKQISLTG 76 + L +G ++ VLP L+ S V + LL L +++ +P G G Sbjct: 12 STVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFG 71 Query: 77 SKTVVLWALGGYGVSFTLLGLGSVLMATGAVTKAVGLGILIIARIVYGLTVSAMVPACQV 136 + V+L +L G V + ++ L +L I RIV G+T + A Sbjct: 72 RRPVLLVSLAGAAVDYAIMATAPFLW------------VLYIGRIVAGITGATGAVAGAY 119 Query: 137 WALQRAGEGNRMAALATISSGLSCGRLFGPLCAAAMLVIHPLAPVWM--LMAAPALALVM 194 A R +S+ G + GP+ M P AP + + Sbjct: 120 IA-DITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGC 178 Query: 195 LLRLPGTPPQPTPERK-------SVSLKRDFLPYLLCAMLLAAAMSMMQLGLSPAL---- 243 L + P R+ S R A L+A M +G PA Sbjct: 179 FLLPESHKGERRPLRREALNPLASFRWARGMTVV---AALMAVFFIMQLVGQVPAALWVI 235 Query: 244 --TRQFATDTTTISQQVAWLLGLSAIA-ALIAQFVVLRPQRLTPVALLLSAGVLMSSGLA 300 +F D TTI +A L ++A A+I V R AL+L + + Sbjct: 236 FGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERR--ALMLGMIADGTGYIL 293 Query: 301 IMLAEQLWLFYLGCAVLSFGAALATPAYQLLLNDKLADGAGAGWLACSHTLGYGLCALLV 360 + A + W+ + +L+ G + PA Q +L+ + D G L L Sbjct: 294 LAFATRGWMAFPIMVLLASG-GIGMPALQAMLS-RQVDEERQGQLQ----------GSLA 341 Query: 361 PLVSKTGVAIALIVMALFAA 380 L S T + L+ A++AA Sbjct: 342 ALTSLTSIVGPLLFTAIYAA 361
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 90.3 bits (223), Expect = 4e-22 Identities = 89/331 (26%), Positives = 141/331 (42%), Gaps = 30/331 (9%) Query: 67 AVGSGAAILDADKSMAVGNNTAVFNADNSVALGYGSQVNGESNVLSVGAGPSGY-----G 121 V GA +D +AVG N+ +A NSVA+G+ S V S+ G Sbjct: 127 GVAIGARASTSDTGVAVGFNSKA-DAKNSVAIGHSSHVAANHG-YSIAIGDRSKTDRENS 184 Query: 122 FSVDGAPETRRIINVSDGVKDSDAATKGQMDNAIADAVRESGDALRGEIGAVYRDAVADA 181 S+ R++ +++ G KD+DA Q+ I + + A + Sbjct: 185 VSIGHESLNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQENTNKRSAELLANANAYADNKS 244 Query: 182 KSRVESAENRLNGNITAARASAQEYTDAVKSDVLDETRTYTDSSVRTVRNEVKSQAEHLS 241 S + A N + +A++ A DVL+ + +++S RT + A ++ Sbjct: 245 SSVLGIANNYTDSKSAETLENARKEAFAQSKDVLNMAKAHSNSVARTTLETAEEHANSVA 304 Query: 242 DVLVK------NRAQTDAAIASNTAAIRNNSHRLDLTEAWQKMAT--------------- 280 ++ N+ +A ++N A +SH L ++ + Sbjct: 305 RTTLETAEEHANKKSAEALASANVYADSKSSHTLKTANSYTDVTVSNSTKKAIRESNQYT 364 Query: 281 -ERMNNMQEQIKENRKELRESAAQSAALAGLFQPYSVGKFNATAAVGGYRDEQAIAVGVG 339 + + ++ + + + A SAAL LFQPY VGK N TA VGGYR QA+A+G G Sbjct: 365 DHKFRQLDNRLDKLDTRVDKGLASSAALNSLFQPYGVGKVNFTAGVGGYRSSQALAIGSG 424 Query: 340 YRFTENVAGKVAVA-AGGSSASWNAGVNFEF 369 YR ENVA K VA AG S +NA N E+ Sbjct: 425 YRVNENVALKAGVAYAGSSDVMYNASFNIEW 455
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 33.4 bits (76), Expect = 6e-04 Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 10/125 (8%) Query: 137 ITNFLQLVLTWSLLIILS--CGVGLIF----MVVGKTFPEMQKVL---PILLKPLYFISC 187 + L SLL L GL F MVV P + +++ P+ F+S Sbjct: 135 VAAALGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSG 194 Query: 188 IMFPLHSIPKQYWSYLLWNPLVHVVELSREAVMPGYISE-GVSLNYLAMFTLVTLFIGLA 246 +FP+ +P + + + PL H ++L R ++ + + + L ++ ++ F+ A Sbjct: 195 AVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTA 254 Query: 247 LYRTR 251 L R R Sbjct: 255 LLRRR 259
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 28.7 bits (64), Expect = 0.010 Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 1 MRRARAGFTLLEMLVAIAIFASLA-LMAQQVTNGVTRVNSAVAGHD 45 + R GFTLLE++V I I LA L+ + + + A D Sbjct: 4 TDKQR-GFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSD 48
>PilS_PF08805#PilS N terminal Length = 185 Score = 33.8 bits (77), Expect = 9e-05 Identities = 15/52 (28%), Positives = 26/52 (50%) Query: 3 RGFTLLEVILALAIFALAATAVLQIASGALSNQQILEEKTVAGWVAENQTAL 54 +G TL+EV+L + + + A + ++ S SN Q E+ V N +L Sbjct: 26 KGATLMEVLLVVGVIVVLAASAYKLYSMVQSNIQSSNEQNNVLTVIANMKSL 77
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 77.7 bits (191), Expect = 2e-20 Identities = 38/166 (22%), Positives = 65/166 (39%), Gaps = 28/166 (16%) Query: 1 MPERGFTLLEIMLVIFLIGLASAGVVQTFATASEPPAKKAAQDFLTRFAQFKDRAVIEGQ 60 M +RGFTLLE+ML++ L+G+++ V+ F + + A + F + + R + GQ Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQ 60 Query: 61 TLGVLIDPPGYQFMQRRHGQWLPVSATRLSAQVTVPKQVQMLLQPGSDIWQKEYALELQR 120 GV + P +QF+ + P D W L L+ Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPA-------------------PADDGWSGYRWLPLRA 101 Query: 121 RRL----TLHDIELEL-----QKEAKKKTPQIRFSPFEPVTPFTLR 157 R+ ++ +L L + P + P +TPF L Sbjct: 102 GRVATSGSIAGGKLNLAFAQGEAWTPGDNPDVLIFPGGEMTPFRLT 147
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 218 bits (556), Expect = 2e-76 Identities = 91/146 (62%), Positives = 109/146 (74%), Gaps = 3/146 (2%) Query: 6 RTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKADRQKAISDIVALENALDMYRL 65 R + GFTLLE+MVVIVI+GVLASLVVPNL+GNKEKAD+QKA+SDIVALENALDMY+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 66 DNGRYPTTEQGLEALIQQPANMADARNYRTGGYIKRLPKDPWGNDYQYLSPGEKGLFDVY 125 DN YPTT QGLE+L++ P A NY GYIKRLP DPWGNDY ++PGE G +D+ Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLL 121 Query: 126 TLGADGQENGEGAGADIGNWNLQEFQ 151 + G DG+ E DI NW L + + Sbjct: 122 SAGPDGEMGTED---DITNWGLSKKK 144
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 454 bits (1170), Expect = e-161 Identities = 225/406 (55%), Positives = 300/406 (73%), Gaps = 1/406 (0%) Query: 1 MALFYYQALERNGRKTKGMIEADSARHARQLLRGKDLIPVHI-EARMNASAGGMLQRRRH 59 MA ++YQAL+ G+K +G EADSAR ARQLLR + L+P+ + E R + G Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 60 AHRRVAAADLALFTRQLATLVQAAMPLETCLQAVSEQSEKLHVKSLGMALRSRIQEGYTL 119 R++ +DLAL TRQLATLV A+MPLE L AV++QSEK H+ L A+RS++ EG++L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 120 SDSLREHPRVFDSLFCSMVAAGEKSGHLDVVLNRLADYTEQRQRLKSRLLQAMLYPLVLL 179 +D+++ P F+ L+C+MVAAGE SGHLD VLNRLADYTEQRQ+++SR+ QAM+YP VL Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 180 VVATGVVTILLTAVVPKIIEQFDHLGHALPASTRMLIAMSDALQASGVYWLAGLLGLLVL 239 VVA VV+ILL+ VVPK++EQF H+ ALP STR+L+ MSDA++ G + L LL + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 GQRLLKNPAMRLRWDKTLLRLPVTGRVARGLNTARFSRTLSILTASSVPLLEGIQTAAAV 299 + +L+ R+ + + LL LP+ GR+ARGLNTAR++RTLSIL AS+VPLL+ ++ + V Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 300 SANRYVEQQLLLAADRVREGSSLRAALADLRLFPPMMLYMIASGEQSGELETMLEQAAIN 359 +N Y +L LA D VREG SL AL LFPPMM +MIASGE+SGEL++MLE+AA N Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 360 QEREFDTQVGLALGLFEPALVVVMAGVVLFIVIAILEPMLQLNNMV 405 Q+REF +Q+ LALGLFEP LVV MA VVLFIV+AIL+P+LQLN ++ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 576 bits (1485), Expect = 0.0 Identities = 295/668 (44%), Positives = 431/668 (64%), Gaps = 34/668 (5%) Query: 24 LLPLVLAAALCSSPVWAEEATFTANFKDTDLKSFIETVGANLNKTIIMGPGVQGKVSIRT 83 L L++ AAL P AEE F+A+FK TD++ FI TV NLNKT+I+ P V+G +++R+ Sbjct: 11 SLTLLIFAALLFRPAAAEE--FSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRS 68 Query: 84 MTPLNERQYYQLFLNLLEAQGYAVVPMENDVLKVVKSSAAKVEPLPLVGEGSDNYAGDEM 143 LNE QYYQ FL++L+ G+AV+ M N VLKVV+S AK +P+ + + GDE+ Sbjct: 69 YDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPG-IGDEV 127 Query: 144 VTKVVPVRNVSVRELAPILRQMIDSAGSGNVVNYDPSNVIMLTGRASVVERLTEVIQRVD 203 VT+VVP+ NV+ R+LAP+LRQ+ D+AG G+VV+Y+PSNV+++TGRA+V++RL +++RVD Sbjct: 128 VTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVD 187 Query: 204 HAGNRTEEVIPLDNASASEIARVLESLTKNSGENQ-PATLKSQIVADERTNSVIVSGDPA 262 +AG+R+ +PL ASA+++ +++ L K++ ++ P ++ + +VADERTN+V+VSG+P Sbjct: 188 NAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPN 247 Query: 263 TRDKMRRLIRRLDSEMERRGNSQVFYLKYSKAEDLVDVLKQVSGTLTAAKEEAEGTVGSG 322 +R ++ +I++LD + +GN++V YLKY+KA DLV+VL +S T+ + K+ A+ + Sbjct: 248 SRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPV-AAL 306 Query: 323 REVVSIAASKHSNALIVTAPQDIMQSLQSVIEQLDIRRAQVHVEALIVEVAEGSNINFGV 382 + + I A +NALIVTA D+M L+ VI QLDIRR QV VEA+I EV + +N G+ Sbjct: 307 DKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGI 366 Query: 383 QWGSKDAGLMQFANGTQIPIGTLGAAISAAKPQKGSTVISENGATTINPDTNGDLST-LA 441 QW +K+AG+ QF N + +PI T A + +G +S+ LA Sbjct: 367 QWANKNAGMTQFTN-SGLPISTAIAG-------------------ANQYNKDGTVSSSLA 406 Query: 442 QLLSGFSGTAVGVVKGDWMALVQAVKNDSSSNVLSTPSITTLDNQEAFFMVGQDVPVLTG 501 LS F+G A G +G+W L+ A+ + + +++L+TPSI TLDN EA F VGQ+VPVLTG Sbjct: 407 SALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTG 466 Query: 502 STVGSNNSNPFNTVERKKVGIMLKVTPQINEGNAVQMVIEQEVSKVEGQTS-----LDVV 556 S S N FNTVERK VGI LKV PQINEG++V + IEQEVS V S L Sbjct: 467 SQTTSG-DNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGAT 525 Query: 557 FGERKLKTTVLANDGELIVLGGLMDDQAGESVAKVPLLGDIPLIGNLFKSTADKKEKRNL 616 F R + VL GE +V+GGL+D ++ KVPLLGDIP+IG LF+ST+ K KRNL Sbjct: 526 FNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNL 585 Query: 617 MVFIRPTILRDGMAADGVSQRKYNYMRAEQIYR--DEQGLSLMPHTAQPILPAQNQALPP 674 M+FIRPT++RD S +Y Q + E +++ I P Q+ A Sbjct: 586 MLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYPRQDTAAFR 645 Query: 675 EVRAFLNA 682 +V A ++A Sbjct: 646 QVSAAIDA 653
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 117 bits (294), Expect = 3e-33 Identities = 67/286 (23%), Positives = 114/286 (39%), Gaps = 38/286 (13%) Query: 40 IARGMFWLMLLIISAKVAHSLWRYFSFSAEYMAVSPSANKPLRADAKAFDKNDVQLISQQ 99 I R +F+L++L+ ++A WR S P +A + ND L Sbjct: 14 IRRILFYLLMLLFCQQLAMIFWR-IGLPDNAPVSSVQIT-PAQARQQPVTLNDFTL---- 67 Query: 100 NWFGKYQPV--ATPVKQPEPAPVAETRLNVVLRGIAFG---ARPGAVIEEGGKQQVYLQG 154 FG A + + + + + LN+ L G+ G +R A+I + +Q Sbjct: 68 --FGVSPEKNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRGVN 125 Query: 155 ETLGSHNAVIEEINRDHVMLRYQGKMERLSLAEEKRPTIAVTSKKAVSDEAKQAVAEPAA 214 E + +NA I I D V+L+YQG+ E L L + + Sbjct: 126 EEVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQ-----------------------EDS 162 Query: 215 SAPVEIPAAVRQAL-AKDPQKIFNYIQLTPVRKEG-IVGYAVKPGADRSLFDASGFKEGD 272 + A V + L + + +Y+ +P+ + + GY + PG F G ++ D Sbjct: 163 GSDGVPGAQVNEQLQQRASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDND 222 Query: 273 IAIALNQQDFTDPRAMIALMRQLPSMDSIQLTVLRKGARYDISIAL 318 +A+ALN D D M ++ + + LTV R G R DI + Sbjct: 223 MAVALNGLDLRDAEQAKKAMERMADVHNFTLTVERDGQRQDIYMEF 268
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 279 bits (715), Expect = 1e-96 Identities = 109/271 (40%), Positives = 149/271 (54%), Gaps = 12/271 (4%) Query: 1 MLFDVFQQYPTAMPVLATVGGLIIGSFLNVVIWRYPIML-RQQMAEFHGEMSSAQSKI-- 57 +L ++ P L + L+IGSFLNVVI R PIML R+ AE+ + + Sbjct: 3 LLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDE 62 Query: 58 ---SLALPRSHCPHCQQTIRIRDNIPLFSWLMLKGRCRDCQAKISKRYPLVELLTALAFL 114 +L +PRS CPHC I +NIPL SWL L+GRCR CQA IS RYPLVELLTAL + Sbjct: 63 PPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSV 122 Query: 115 LASLVWPESGWALAVMILSAWLIAASVIDLDHQWLPDVFTQGVLWTGLSAAWAQQSPLTL 174 ++ LA ++L+ L+A + IDLD LPD T +LW GL ++L Sbjct: 123 AVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNL-LGGFVSL 181 Query: 175 QDAVTGVLVGFIAFYSLRWIAGIVLRKEALGMGDVLLFAALGSWVGPLSLPNVALIASCC 234 DAV G + G++ +SL W ++ KE +G GD L AALG+W+G +LP V L++S Sbjct: 182 GDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLV 241 Query: 235 GLIYAVI-----TKRGSTTLPFGPCLSLGGI 260 G + S +PFGP L++ G Sbjct: 242 GAFMGIGLILLRNHHQSKPIPFGPYLAIAGW 272
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 48.8 bits (116), Expect = 6e-08 Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 3/60 (5%) Query: 32 SSDTPPVDSGTGSLPEVKPDPTPNPEPTPEPTPDPEPTPEP---IPDPEPTPEPEPEPVP 88 S T + V+P P P EP PEP P PEP E I P+P P+P+P+PV Sbjct: 50 ISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 109 Score = 41.9 bits (98), Expect = 1e-05 Identities = 16/92 (17%), Positives = 27/92 (29%), Gaps = 2/92 (2%) Query: 33 SDTPPVDSGTGSLPEVKPDPTPNPEPTPEPTPDPEPTPEPIPDPEPTPEPEPEPVPTKTG 92 +D P + PE +P P PEP PEP + E + V Sbjct: 58 ADLEPPQAVQ-PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKR 116 Query: 93 YLTLGGSQRVTGATCNGESSDGFTFKPGEDVT 124 + S+ + N + + + Sbjct: 117 DVKPVESRPASPFE-NTAPARPTSSTATAATS 147 Score = 40.7 bits (95), Expect = 2e-05 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%) Query: 35 TPPVDSGTGSLPEVKPDPTPNPEPTPEPTPDPEPTPEPIPDP--EPTPEPEPEPVPTKT 91 P + +P +P PEP +PEP PEPIP+P E E K Sbjct: 45 APAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 103 Score = 40.3 bits (94), Expect = 3e-05 Identities = 20/96 (20%), Positives = 28/96 (29%), Gaps = 7/96 (7%) Query: 29 SGSSSDTPPVDSGTGSLPEVKPDPTPNPEPT---PEPTPDPEPTPEPIPDPEPTPEPEPE 85 + P V PE +P P P E +P P P+P P+P+ E Sbjct: 65 AVQPPPEPVV----EPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKP 120 Query: 86 PVPTKTGYLTLGGSQRVTGATCNGESSDGFTFKPGE 121 R T +T +S T Sbjct: 121 VESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Score = 35.0 bits (80), Expect = 0.002 Identities = 17/40 (42%), Positives = 17/40 (42%) Query: 50 PDPTPNPEPTPEPTPDPEPTPEPIPDPEPTPEPEPEPVPT 89 P P T D EP P PEP EPEPEP P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPI 83 Score = 30.3 bits (68), Expect = 0.043 Identities = 11/40 (27%), Positives = 13/40 (32%) Query: 52 PTPNPEPTPEPTPDPEPTPEPIPDPEPTPEPEPEPVPTKT 91 P P + + P P P P EPEP P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPI 83
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.0 bits (96), Expect = 6e-06 Identities = 59/329 (17%), Positives = 107/329 (32%), Gaps = 37/329 (11%) Query: 34 PTLMEELNISTQQ---YSYIIAAYSAAYTVMQPVAGYVLDVLGTK----IGYAMFAVLWA 86 P L+ +L S Y ++A Y+ PV G + D G + + A AV +A Sbjct: 29 PGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYA 88 Query: 87 VFCGATALAGSWGGLAVA--RGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSS 144 + A L + G VA GA GA A I ++ ER+ G+ + Sbjct: 89 IMATAPFLWVLYIGRIVAGITGATGAVAGAYI-------ADITDGDERARHFGFMSACFG 141 Query: 145 IGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIIN 204 G M+A P++ + S F + AL+ + + K R +N Sbjct: 142 FG-MVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES--HKGERRPLRREALN 198 Query: 205 GQEAQHQVDTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKE 264 + ++ + F+ + L + W +F + ++ Sbjct: 199 PLASFRWARGMTVVAALMAV----FFIMQLVGQVPAALWV-------IFGEDRFHWDATT 247 Query: 265 IAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVV-TLGAVLMIGPGMIGLFT 323 I + F L + + G + M+ G +L+ + Sbjct: 248 IGI---SLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMA- 303 Query: 324 NPYVAIMLLCIGGFAHQALSGALITLSSD 352 + ++LL GG AL L + Sbjct: 304 --FPIMVLLASGGIGMPALQAMLSRQVDE 330
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 78.0 bits (192), Expect = 9e-17 Identities = 73/433 (16%), Positives = 139/433 (32%), Gaps = 30/433 (6%) Query: 285 NSRVDAYRNEQLLGSFYLNSGSQFIDTSSFPPGSYSVALKVYENNQLTRTELVPFTKTGG 344 ++V +N + + + G I+ S + + + E + T+ VP++ Sbjct: 308 TAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPL 367 Query: 345 LT-DGNAQWFLQAGKTTSQVS-DDESSAYQLGVRLPLHPQYELYAGLANADDVSAFELGN 402 L +G+ ++ + AG+ S + ++ +Q + L + +Y G AD AF G Sbjct: 368 LQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGI 427 Query: 403 NWTADLGGAGNLAISASVFRNDDGGKGDMQQANWSH-PGWPTLGF------YRTNSDGDA 455 GA ++ ++ + D + D Q + + G YR ++ G Sbjct: 428 GKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYF 487 Query: 456 CTTDNRESYNALSCYES--ISATVSQNFVGWNMMLGYTRTQNNTDDSLRWDKQQSFENNY 513 D S E+ V F + + R + + + + + + Sbjct: 488 NFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSG 547 Query: 514 LRQT--SAQSISETVQLSASRAFVMRDWILSTSLGVFHRNDNGGGSDDNGLYLSFS--LS 569 QT ++ E Q + AF ++ +L + D L L+ + S Sbjct: 548 SHQTYWGTSNVDEQFQAGLNTAFED----INWTLSYSLTKNAWQKGRDQMLALNVNIPFS 603 Query: 570 DTPTMDSNNNSHSTNVSTDYRYSDQDGDQTSWQLSHTFYNDSFSHKEL--GVTVGGLNTD 627 DS + + S + + T D+ + G GG Sbjct: 604 HWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNS 663 Query: 628 TINSAVNGRWDGQYGNVYATVSDSYDRQNHDHLSAFTGTYSSTLAVSRYGINLGASGSDD 687 + G YGN S S D + S + G+ LG +D Sbjct: 664 GSTGYATLNYRGGYGNANIGYSHSDDIKQ------LYYGVSGGVLAHANGVTLGQPLND- 716 Query: 688 LLGAVLVDVKGFS 700 VLV G Sbjct: 717 --TVVLVKAPGAK 727 Score = 32.1 bits (73), Expect = 0.012 Identities = 40/222 (18%), Positives = 68/222 (30%), Gaps = 35/222 (15%) Query: 299 SFYLNSGSQFIDTSSF------PPGSYSVALKVYENNQLTRTELVPFTKTGGLTDGNAQW 352 F + D S F PPG+Y V + + NN T V F Sbjct: 52 RFLADDPQAVADLSRFENGQELPPGTYRVDIYL--NNGYMATRDVTFNTGDSEQG----- 104 Query: 353 FLQAGKTTSQVSDDESSAYQLGVRLPLHPQYELYAGLANADDVSAFELGNNWTADLG-GA 411 + T +Q++ +G+ L A A S D+G Sbjct: 105 -IVPCLTRAQLA-------SMGLNTASVSGMNLLADDACVPLTSMIH-DATAQLDVGQQR 155 Query: 412 GNLAISASVFRNDDGGKGDMQQANWSHPGWPTLGFYRTNSDGDACTTDNRESYNALSCYE 471 NL I + N +G + W L Y + + NR N+ Y Sbjct: 156 LNLTIPQAFMSNRA--RGYIPPELWDPGINAGLLNYNFS----GNSVQNRIGGNSHYAYL 209 Query: 472 SISATVSQNFVGW----NMMLGYTRTQNNTDDSLRWDKQQSF 509 ++ + + N W N Y + +++ +W ++ Sbjct: 210 NLQSGL--NIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTW 249
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 536 bits (1383), Expect = 0.0 Identities = 173/397 (43%), Positives = 254/397 (63%), Gaps = 11/397 (2%) Query: 7 VLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVN-GGEPAP--LAHHSYEGA 63 +LVINCGSSS+K+ ++++ D VL G+A+ I ++ L+ N GE ++ A Sbjct: 3 ILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDA 62 Query: 64 LKAIAFELEKRNLN-----DSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLH 118 +K + L + + +GHR+ HGG FT S +ITD+V+ I LAPLH Sbjct: 63 IKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPLH 122 Query: 119 NYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTS 178 N AN+ GI++ Q+ P V VAVFDT+FHQTM AYLY +P++YY + +R+YGFHGTS Sbjct: 123 NPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGTS 182 Query: 179 HRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSG 238 H+YVSQRA +LN + ++ HLGNG+SI AV+NG+S+DTSMG TPLEGL MGTRSG Sbjct: 183 HKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRSG 242 Query: 239 DVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLR-VLEKAWHEGHERAQLAI 297 +D +S++ + N S ++ ++NK+SG+ GISG+SSD R + + A+ G +RAQLA+ Sbjct: 243 SIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQLAL 302 Query: 298 KTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRS 357 F +R+ + I +AA++ +D I+FT GIGEN IR +++ L LG ++D E N Sbjct: 303 NVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNKVR 362 Query: 358 NSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGK 394 E I+S+ +++V V+PTNEE MIA D + + Sbjct: 363 GE--EAIISTADSKVNVMVVPTNEEYMIAKDTEKIVE 397
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 28.5 bits (63), Expect = 0.017 Identities = 30/144 (20%), Positives = 53/144 (36%), Gaps = 17/144 (11%) Query: 57 ALSYRLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAKLTNDRMLYLYGHVE 116 AL +I + + +A L D+ K +K D+ T+D YL G ++ Sbjct: 307 ALDLLVINKQQSNFQKEAHEIIFDLALDGADQTKEQL--IKTDEELGTDDEDFYLKGAMQ 364 Query: 117 ----VNALVPDSQLRRITT----------DNAQINLVTQDVTSEDLVTLYGTTFNSSGLK 162 VN + P + +T + + T +TSE Y T + K Sbjct: 365 NFSYVNYVSPLKVISDPSTGIVSSKKNNAEMKSKQMSTDQMTSEKEFDYYTETLKALLEK 424 Query: 163 M-RGNLRSKNAELIEKVRTSYEIQ 185 L +L+E ++ +Y I+ Sbjct: 425 EDSAELNENEKKLVETIKKAYTIE 448
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.9 bits (158), Expect = 6e-13 Identities = 26/115 (22%), Positives = 45/115 (39%), Gaps = 4/115 (3%) Query: 528 VLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFKPGEYDLVLLDIQLPDMTGLDI 587 +L+ +D V L + G V + G+ DLV+ D+ +PD D+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 588 SRELTKRYPREDLPPLVALTA-NVLKDKQEYLNAGMDDVLSKPLSVPALTAMIKK 641 + K P P++ ++A N + G D L KP + L +I + Sbjct: 66 LPRIKKARPD---LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>cloacin#Cloacin signature. Length = 551 Score = 29.3 bits (65), Expect = 0.032 Identities = 14/39 (35%), Positives = 20/39 (51%) Query: 100 VSEWLTSRQQRAVRKEEKKEQAEAKAADPQAAAKREAAR 138 VS+ L+ Q + + EE + Q E A P AA+R R Sbjct: 287 VSDVLSPDQVKQRQDEENRRQQEWDATHPVEAAERNYER 325
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 60.3 bits (146), Expect = 7e-12 Identities = 64/406 (15%), Positives = 135/406 (33%), Gaps = 32/406 (7%) Query: 30 LLDGFDFVLIALVLTEVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMV 89 + +++ + L ++ +F + +A ++ G + G + D+ G + ++ Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 90 TSIVLFSAGTLACGFAPGYITMFI-ARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGF 148 I++ G++ + ++ I AR + G G A V PK R KA G Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 149 LISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHGGKA 208 + S ++G V + ++ W L I ++ II +L K + + Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVR--------- 194 Query: 209 PVRTMVDILYRGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQ 268 +G I I++ + IV+VL L IF+ + + Sbjct: 195 ---------IKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL---IFVKHIRK 242 Query: 269 STGK----RWPTGVMLMVVVLFAFLYSWPIQA---LLPTYLKTDLAYDPHTVANVLFFSG 321 T + M+ VL + + ++P +K + +V+ F G Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 322 -FGAAVGCCVGGFLGDWLGTRK-AYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQML 379 + +GG L D G + S + F + W + +++ F Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLET-TSWFMTIIIVFVLGG 361 Query: 380 GQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPIIGALI 425 ++ ++ + AG+ L I + Sbjct: 362 LSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 43.5 bits (102), Expect = 2e-06 Identities = 41/203 (20%), Positives = 67/203 (33%), Gaps = 10/203 (4%) Query: 126 APSTSSSDQTASGEKSIDLAGNATDQANGVQPAPGTTSAENTQQDVSLPPISST-PTQGQ 184 P+ +D + + ++A D+A PAP T S + S T Q Sbjct: 999 TPNNIQADVPSVPSNNEEIA--RVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 185 TPAATDGQQRVEVQGDLNNALTQPQN----QQQLNNVAVNSTLPTEPATVAPVRNGNASR 240 T Q R + +N Q Q +T E ATV + A Sbjct: 1057 DATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE--KEEKAKV 1114 Query: 241 DTAKTQTAERPATTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAA 300 +T KTQ + + +Q+ E +PQA E P + A T+ PA Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQS-ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 301 TSTPAPKETATTAPVQTASPAQT 323 ++ ++ T + + Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVV 1196 Score = 42.4 bits (99), Expect = 3e-06 Identities = 38/199 (19%), Positives = 68/199 (34%), Gaps = 19/199 (9%) Query: 143 DLAGNATDQANGVQPAPGTTSAENTQQDVSL-----------------PPISSTPTQGQT 185 DL ++ N T+ N Q DV PP +TP++ Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038 Query: 186 PAATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPATVAPVRNGNASRDTAKT 245 A + +Q + T+ Q + S + T ++G+ +++T T Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 246 QTAERPATTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAATSTPA 305 +T E + + + E + V ++ P + + +P A A P Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 306 PKETATTAPVQTASPAQTT 324 +T TTA T PA+ T Sbjct: 1159 QSQTNTTA--DTEQPAKET 1175
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 33.6 bits (77), Expect = 4e-04 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 18/91 (19%) Query: 84 FYDSDQEIEKRTGADVGWVFDLEGEEGFRD----------REEKVINELTEKQGIVLATG 133 FYD + KR + GW+ + G+R E + I +L E+ IV+A+G Sbjct: 136 FYDEETA--KRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLVERGVIVIASG 193 Query: 134 GGSVKSRETRNRLSARGVVVYLETTIEKQLA 164 GG V + +GV E I+K LA Sbjct: 194 GGGVPVILEDGEI--KGV----EAVIDKDLA 218
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 284 bits (727), Expect = 2e-92 Identities = 80/301 (26%), Positives = 131/301 (43%), Gaps = 18/301 (5%) Query: 117 LENRNITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDNKTALSALEQWVAQMDL 176 L + I D + +A SA+ + D N +++RD+ + ++ + +D Sbjct: 219 LSDATIQQVTVDNQRIPQAAT-RASAQARVEADPSLNAIIVRDSPERMPMYQRLIHALDK 277 Query: 177 PVGQVELSAHIVTINEKSLRELGVKWTLADAQQAGGVGQVTTLGSDLSVATATTHVGFNI 236 P ++E++ IV IN L ELGV W + + T G ++A+ G Sbjct: 278 PSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASN----GALG 333 Query: 237 GRINGRLLDL---ELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGAT 293 ++ R LD ++ LE + +++ P LL A I SE Y +G+ A Sbjct: 334 SLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDH-SETYYVKVTGKEVA- 391 Query: 294 SVEFKEAVLG--MEVTPTVLQKG---RIRLKLHISQNVPGQVLQQADGEVLAIDKQEIET 348 E K G + +TP VL +G I L LHI +G + I + ++T Sbjct: 392 --ELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIEG-IPTISRTVVDT 448 Query: 349 QVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERRELVVFITPRL 408 V G++L +GGI+ + VPLLGDIP+ G LFR + R + I PR+ Sbjct: 449 VARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVRLFIIEPRI 508 Query: 409 V 409 + Sbjct: 509 I 509 Score = 36.8 bits (85), Expect = 2e-04 Identities = 18/95 (18%), Positives = 33/95 (34%), Gaps = 4/95 (4%) Query: 1 MKQWIAALLLMLIPGVQAA----KPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSG 56 K+ + LL+L A P + + +L +VVS ++ Sbjct: 9 FKRVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKIND 68 Query: 57 TVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSV 91 VS + LQ + L+ +GN+L + Sbjct: 69 KVSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYI 103
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 33.2 bits (75), Expect = 0.003 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 17/82 (20%) Query: 276 RTPISGEYRGYQVYSMPPPSSGGIHIVQILNI--LENFDMKKYGF-GSADAMQIMAEAEK 332 R P+ GE R + SMPPP G H +I N+ + FD G+ G A I++E EK Sbjct: 77 RRPM-GETRNVSLISMPPPWRPGEHADRITNLKFFKQFD----GYVGGQTAWGILSELEK 131 Query: 333 YAYADRSEYLGDPDFVKVPWQA 354 Y P F WQ+ Sbjct: 132 GRY---------PTFSYQDWQS 144
>PF04619#Dr-family adhesin Length = 160 Score = 28.7 bits (64), Expect = 0.014 Identities = 12/60 (20%), Positives = 23/60 (38%), Gaps = 4/60 (6%) Query: 29 VGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGDLNWQD----LLRVDAGSW 84 +G ++ D + G+ FL+ D+N ++ + W + D GSW Sbjct: 70 LGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDNSAWTTDNGVFYKNDVGSW 129
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.042 Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 33 IVMVGPSGCGKSTLLRMVAGLERVTTGDI 61 +V+ G G GKSTL+ + GL+ + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHF 627
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 38.9 bits (90), Expect = 3e-05 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 14/160 (8%) Query: 134 GHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQDLADYAAKLKASGMKCGYASGWQ 193 G L++ P L YNKD PPKTW+++ +LKA G + + Sbjct: 127 GKLIAYPIAVEALSLIYNKDLLP-------NPPKTWEEIPALDKELKAKGKSALMFNLQE 179 Query: 194 GWIQLENFSAWNGLPFASKNNGFDGTDAVLEF--NKPEQVKHIAMLEEMNKKGDFSYVGR 251 + +A G F +N +D D ++ K + +++ + D Y Sbjct: 180 PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDY--- 236 Query: 252 KDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMP 291 + F G+ AMT + +NI + +K NYGV ++P Sbjct: 237 -SIAEAAFNKGETAMTINGPWAWSNI-DTSKVNYGVTVLP 274
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 55.1 bits (132), Expect = 6e-10 Identities = 39/206 (18%), Positives = 67/206 (32%), Gaps = 1/206 (0%) Query: 19 EQTPEKETEVQNEQPVVEEIVPAQEPVKASEQTVEEQPQAHTEAEAETFAADVVEVTEQV 78 TP + TE E E + A+E T + + A EV + Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSG 1089 Query: 79 AESEKAQPEAVAEPEVITEPETIVEETPASVIEPEVTPE-PVAIEREELPLPEDVNAEEV 137 +E+++ Q E + + E ET + P+VT + E+ E P+ A E Sbjct: 1090 SETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREN 1149 Query: 138 SPEEWQAEAETLEIVEAAEEEAAKEDITDEELEAQALAAEAAEEAVMVVSPAEEEQPVEE 197 P E ++ A E+ AKE ++ E +V+ + Sbjct: 1150 DPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQP 1209 Query: 198 IAQEQEKPTKEGFFARLKRSLLKTKE 223 + + R RS+ E Sbjct: 1210 TVNSESSNKPKNRHRRSVRSVPHNVE 1235 Score = 43.5 bits (102), Expect = 2e-06 Identities = 41/201 (20%), Positives = 67/201 (33%), Gaps = 19/201 (9%) Query: 17 QKEQTPEK------ETEVQNEQPVVEEIVPAQEPVKASEQTVEEQPQAHTEAEAETFAAD 70 Q+ +T EK ET QN + E A+ VKA+ QT E E +T Sbjct: 1046 QESKTVEKNEQDATETTAQNREVAKE----AKSNVKANTQTNEVAQSGSETKETQTTET- 1100 Query: 71 VVEVTEQVAESEKAQPEA---VAEPEVITE--PETIVEETPASVIEPEVTPEPVAIEREE 125 + T V + EKA+ E P+V ++ P+ ET EP +P + +E Sbjct: 1101 --KETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPT-VNIKE 1157 Query: 126 LPLPEDVNAEEVSPEEWQAEAETLEIVEAAEEEAAKEDITDEELEAQALAAEAAEEAVMV 185 + A+ P + + + E+ + + E A Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 186 VSPAEEEQPVEEIAQEQEKPT 206 + V + E T Sbjct: 1218 KPKNRHRRSVRSVPHNVEPAT 1238 Score = 43.1 bits (101), Expect = 2e-06 Identities = 25/171 (14%), Positives = 56/171 (32%), Gaps = 9/171 (5%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVPAQEPVKASEQTVEEQPQAHTEAEAETFAADVVEVTE 76 +T E +T E VE+ +E K + +E P+ ++ + ++ V+ Sbjct: 1088 SGSETKETQTTETKETATVEK----EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQA 1143 Query: 77 QVAESEKAQPEAVAEPEVIT----EPETIVEETPASVIEPEVTPEPVAIEREELPLPEDV 132 + E + EP+ T + E +ET ++V +P V + PE+ Sbjct: 1144 E-PARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENT 1202 Query: 133 NAEEVSPEEWQAEAETLEIVEAAEEEAAKEDITDEELEAQALAAEAAEEAV 183 P + + + ++ + + A + Sbjct: 1203 TPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLT 1253
>PF01206#SirA family protein Length = 76 Score = 104 bits (261), Expect = 1e-33 Identities = 24/71 (33%), Positives = 41/71 (57%) Query: 9 DHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKET 68 D +LDA GL CP P++ +KT+ M GE L ++A DP + +D F HEL+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 69 DGLPYRYLIRK 79 + Y + +++ Sbjct: 65 EDGTYHFRLKR 75
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 53.7 bits (129), Expect = 6e-10 Identities = 82/398 (20%), Positives = 149/398 (37%), Gaps = 32/398 (8%) Query: 24 LRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVM--GFSAFWAGLVISLQYFATLLSR 81 ++ N ++ I+ + IGL + VLPG + D++ G++++L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 82 PHAGRYADLLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGI-GQS 140 P G +D G + +++ L G + + Y L V L +GR++ GI G + Sbjct: 61 PVLGALSDRFGRRPVLLVSLAG---AAVDYAIMATAPFLWV-----LYIGRIVAGITGAT 112 Query: 141 FAGTGSTLWGVGVVGSL--HIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIM 198 A G+ + + H G + + G +G +G H A AL + Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGL 172 Query: 199 GVALVAILLAIP-----RPMVKASKGKPLPFRAVLGRVWLYGMALA--LASAGFGVIATF 251 LL RP+ + + FR G + + + V A Sbjct: 173 NFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL 232 Query: 252 ITLFYDAK-GWDGAAFALTLFSCAFVGT---RLLFPNGINRIGGLNVAMICFSVEIIGLL 307 +F + + WD ++L + + + ++ R+G M+ + G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 308 LVGVATMPWMAKIG-VLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGV 366 L+ AT WMA VLLA G + PAL + + V ++ QG + L+ + Sbjct: 293 LLAFATRGWMAFPIMVLLASGGIGM--PALQAMLSRQVDEERQGQLQGSLAALTSLT-SI 349 Query: 367 TGPLAGLVMSWAGVPV----IYLAAAGLVAIALLLTWR 400 GPL + A + ++A A L + L R Sbjct: 350 VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.021 Identities = 10/34 (29%), Positives = 19/34 (55%) Query: 25 QAVLNNVSLTLKSGETVALLGRSGCGKSTLARLL 58 Q + ++ +++ T+ + G SG GK +AR L Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 50.3 bits (120), Expect = 4e-09 Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 7/171 (4%) Query: 200 REREHGTVEHLLVMPITPFEIMMAKV-WSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPL 258 R T E +L + +I++ ++ W+ L +G+ +V G + L Sbjct: 93 RMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGY----TQWLSLL 148 Query: 259 FMLGV-ALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQD 317 + L V AL+ A S+G+ + +A S LV+ P+ LSG P + +P + Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 318 IMLTMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFF-TIALLRFR 367 +P +H + L + I+ ++ + I FF + ALLR R Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRR 259
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.046 Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 37 ARCMVGLIGPDGVGKSSLLSLISGAR 62 V L G G+GKS+L++ + G Sbjct: 595 FDYSVVLEGTGGIGKSTLINTLVGLD 620
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 84.9 bits (210), Expect = 3e-20 Identities = 72/408 (17%), Positives = 139/408 (34%), Gaps = 81/408 (19%) Query: 6 RHLAWWVVGLLAVAAIVAWWLLRPAGVP-EGFAVSNGRIEATEVDIASKIAGRIDTILVK 64 R +A++++G L +A I++ G +GR + I + I+VK Sbjct: 58 RLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKE----IKPIENSIVKEIIVK 113 Query: 65 EGQFVREGEVLAKMDTRV----------------LQEQRLEAI----------------- 91 EG+ VR+G+VL K+ L++ R + + Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 92 -------------------AQIKEAQSAIAAAQALLEQRQSETRAAQSLVNQRQAELDSV 132 Q Q+ + L+++++E + +N+ + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 133 AKRHTRSRSLAQRGAISAQQLDDDRAAAESARAALESAKAQVSASKAAIEAARTNIIQ-- 190 R SL + AI+ + + A L K+Q+ ++ I +A+ Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 191 -----------AQTRVEAAQATERRIAADID--DSELKAPRDGRV-QYRVAEPGEVLAAG 236 QT T + S ++AP +V Q +V G V+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 237 GRVLNMVDLSDVY-MTFFLPTEQAGTLKLGGEARLILDAAPDLRIPATISFVASVAQFTP 295 ++ +V D +T + + G + +G A + ++A P R V V Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYG---YLVGKVKNINL 410 Query: 296 KTVETSDERLKLMFRVKARIPPELLQQHLEYV--KTGLPGVAWVRVNE 341 +E D+RL L+F V I L + + +G+ A ++ Sbjct: 411 DAIE--DQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.0 bits (65), Expect = 0.032 Identities = 23/98 (23%), Positives = 38/98 (38%), Gaps = 18/98 (18%) Query: 226 ENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFL--NEQRNAHPNQSLKNTL 283 E + RG GP +L + ++ + + + L T + N Q A N LK L Sbjct: 63 EAITLRERGWKGP-ILMLEGFFHAQD---LEIYDQHRLTTCVHSNWQLKALQNARLKAPL 118 Query: 284 AVHL------------PKRLVERLQQLGQIPDVSLKQL 309 ++L P R++ QQL + +V L Sbjct: 119 DIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTL 156
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 32.2 bits (73), Expect = 0.002 Identities = 42/210 (20%), Positives = 73/210 (34%), Gaps = 23/210 (10%) Query: 28 MVKRKKLFT--ALLALSWTFSVTAAE-----RIVVAGGSLTELIYAMGAGKRVVGVDETT 80 ++ R++L T AL L W + A RIV EL+ A+G GV +T Sbjct: 6 LISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVP--YGVADTI 63 Query: 81 SY------PPETARLPHIGYWKQLSSEGILSLRPDSVITWQDAGPQIVLDQL-RAQKVNV 133 +Y PP + +G + + E + ++P ++ GP + L R Sbjct: 64 NYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGP--SPEMLARIAPGRG 121 Query: 134 VTLPRVPATLEQMYANIRQLAKTLQVPEQGEALVTQINQRLERVQQNVAAKKAPVKAMFI 193 L ++ ++A L + E + Q + ++ + A + Sbjct: 122 FNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTT 181 Query: 194 LSAGGSAPQ--VAGKGSVADAILSLAGAEN 221 L V G S+ IL G N Sbjct: 182 LI---DPRHMLVFGPNSLFQEILDEYGIPN 208
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.019 Identities = 15/59 (25%), Positives = 24/59 (40%), Gaps = 4/59 (6%) Query: 5 AQPEDHMISAQNLVYSLQGRRLTDNVSLTFPGG---EIVAIL-GPNGAGKSTLLRQLTG 59 P+D+ + + L +V+ G + +L G G GKSTL+ L G Sbjct: 560 KTPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVG 618
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 24.5 bits (53), Expect = 0.013 Identities = 10/35 (28%), Positives = 14/35 (40%) Query: 6 QNIIRLQPLHFSYEKGRRVLSLRPGPGANCHYGSL 40 Q R PL S + R ++ P H G+L Sbjct: 207 QTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGAL 241
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 67.5 bits (165), Expect = 8e-20 Identities = 18/50 (36%), Positives = 33/50 (66%) Query: 1 MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAAFLACKLKE 50 +P+ + ++++C TLL FT++ R SLCE+ + G E+AAF+A + + Sbjct: 3 LPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK 52
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 27.5 bits (61), Expect = 0.021 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 77 MTCLTVFIISVALLLVGLWNATLLLSEKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKET 136 MT T II LL L + + GLA FL+ F V I P E Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAP-PNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEE 119 Query: 137 QVTQEE 142 +++ +E Sbjct: 120 KISMQE 125
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 436 bits (1123), Expect = e-132 Identities = 244/888 (27%), Positives = 382/888 (43%), Gaps = 145/888 (16%) Query: 50 SPLIQASIVGMDIPYQTYRDFAENKGAFSVGALDIPLYKKDGTLYSTL--NKAPMIDFSA 107 +P +A++V D+ YQ +RDFAENKG FSVGA ++ + K+ T N PMIDFS Sbjct: 20 TPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNKDLGTALPNGIPMIDFSV 79 Query: 108 VDSGQTVATLISPQYIVSVKH-NTGYKNVRFG-------------YRDDSS----YILVD 149 VD + +ATLI+PQY+V VKH + G + FG +RD SS Y V+ Sbjct: 80 VDVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKAHRDVSSEENRYFSVE 139 Query: 150 RNN------------------SSVDFHTPRLNKIVTEVVPADITDAGTANGTYQNQDRFP 191 +N D++ PRL+K VTEV P + + A + GTY +Q+++P Sbjct: 140 KNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDAGTYNDQNKYP 199 Query: 192 IFYRVGTGTQYVKDRNGK--------------LTQLAGGYAYRTGGTVGKPTSSNKRIV- 236 F R+G+G+Q++ + L + Y Y GT K N ++ Sbjct: 200 AFVRLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDAYTYGIAGTPYKVNHENNGLIG 259 Query: 237 -SNPGNTYSAANG-----PMPSYGIPGDSGSPLFAWDTQRNKWVLVAVLNSYAGNAGKTN 290 N +S G P+ +Y + GDSGSPLF +D ++ KW+ + + +AG K + Sbjct: 260 FGNSKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYDFWAGY-NKKS 318 Query: 291 WFTVIPVNEVSANIEADTDAPVTPTSTTENINWTYDISTGTGKLTQGTDAWEMHGRDTGS 350 W + D+ + ++++ + T +T G + + D Sbjct: 319 WQEWNIYKSQFTKDVLNKDSAGS--LIGSKTDYSWSSNGKTSTITGGEKSLNVDLADGKD 376 Query: 351 SAVSFNHGKDLSFENTGTVVLKDIVNQGAGTLTFNGDYIVKPDAD-QTWVGGGIIVNGDH 409 NHGK ++FE +GT+ L + ++QGAG L F GDY VK +D TW G G+ V Sbjct: 377 KP---NHGKSVTFEGSGTLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWKGAGVSVAEGK 433 Query: 410 TVNWQVNGVKGDSMHKLGTGTLNISGTGINPGTLSVGDGTVVLAQKPDSNGQVQAFESAS 469 TV W+V+ + D + K+G GTL + GTG N G+L VGDGTV+L Q+ + +GQ AF S Sbjct: 434 TVTWKVHNPQYDRLAKIGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGSGQ-HAFASVG 492 Query: 470 IVSGRPTLVLSDSQQMNPDNIKWGYRGGKLDINGNDLTFHALNAADEGAILTNSGSLATT 529 IVSGR TLVL+D +Q++P++I +G+RGG+LD+NGN LTF + D+GA L N Sbjct: 493 IVSGRSTLVLNDDKQVDPNSIYFGFRGGRLDLNGNSLTFDHIRNIDDGARLVN------- 545 Query: 530 SLDFNSTDTTKPVTTMFHGFFTGNVNVKNNATSNVNNTFVVDGGINTPAGSMTQQGGRLF 589 ++ +T TG + + T N D N A + GG+L+ Sbjct: 546 ----HNMTNASNIT------ITGESLITDPNTITPYNIDAPDED-NPYAFRRIKDGGQLY 594 Query: 590 FQGHPVIHAVSTQSVANKLKALGDDSVLTQPVSFTQSDWQTRQFNLKSLDLNNAAFYLAR 649 T K + Sbjct: 595 LNLEN----------------------------------YTYYALRKGASTRSELP---- 616 Query: 650 NAGLITTINANNSTVTLGSEDLYIDTNDGNGVKTTPVEGQSVATASEDQSHFTGNVNLTN 709 + +N + + +G N N + + G + E+ + GN+N+T Sbjct: 617 ----KNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGEEEGKN-NGNLNVTF 671 Query: 710 GSALRVNENF--SGGIISSNSSVTISSTNANLTESSMFTHSVIKLSDNAQLTSTAGLQSD 767 F +GG +N + ++ L + D A ++ST Sbjct: 672 -KGKSEQNRFLLTGG---TNLNGDLTVEKGTLF---LSGRPTPHARDIAGISSTKKDPHF 724 Query: 768 GTIEFGNGAKLSLLGESSSTFTPFSATAWNLKGTGSSLNIGSGTNVNGDINAWSDTNINF 827 ++ E F AT N+ G S + + N+ +I A + ++ Sbjct: 725 AENN-------EVVVEDDWINRNFKATTMNVTGNASLYSGRNVANITSNITASNKAQVHI 777 Query: 828 GNSGKQSTSSGILYTGDIYAPEANVSIDNTSWTLNKTSLLGNLTLKNS 875 G + YTG + +S D + N T+L GN+ L S Sbjct: 778 GYKTGDTVCVRSDYTGYVTCTTDKLS-DKALNSFNPTNLRGNVNLTES 824
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 386 bits (992), Expect = e-123 Identities = 192/840 (22%), Positives = 341/840 (40%), Gaps = 83/840 (9%) Query: 5 IFIAAIIFHLLSKGALAEEFNYSFIRGGSKDIPDVLNSNKENV--PGKYVVDVVFNGSKI 62 +F+A + FN F+ + + D+ PG Y VD+ N + Sbjct: 30 LFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYM 89 Query: 63 ASSTEMSIAKEDAEG---ICLSDEWLTENGIIINKDFYKN-VYNSARQCYLLGN-EANSK 117 A+ +++ D+E CL+ L G+ N + C L + ++ Sbjct: 90 AT-RDVTFNTGDSEQGIVPCLTRAQLASMGL--NTASVSGMNLLADDACVPLTSMIHDAT 146 Query: 118 VAFDQSLQEVSIDLPQAGFQDAAK---DGGVWDYGSNGFKIAYDVN--TAKNSNQERTTY 172 D Q +++ +PQA + A+ +WD G N + Y+ + + +N + Y Sbjct: 147 AQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHY 206 Query: 173 SSIDGQ--VNLGEWVL---------LGRGYAYQGENFDTNNLLLTRAIKSLKSDLQLGKT 221 + ++ Q +N+G W L + + N L R I L+S L LG Sbjct: 207 AYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDG 266 Query: 222 QLYNSLNNGFTFYGAQLKSNQDMYPWNSRAYSPVINGIARTHARVTIEQSGYTLKSIVVP 281 + +G F GAQL S+ +M P + R ++PVI+GIAR A+VTI+Q+GY + + VP Sbjct: 267 YTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVP 326 Query: 282 PGPFVINDLNGV-YSGDLIMKIYEEDGSVREQRFPVAVLPNLLRPGTYNYALAMGSKVNQ 340 PGPF IND+ SGDL + I E DGS + P + +P L R G Y++ G + Sbjct: 327 PGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAG-EYRS 385 Query: 341 DNGERDKESLFAQMSYDYGFEP-FTLNSSLLLDKNYNNIGLGLIRSFGWFGAMSFSGNLS 399 N +++K F Q + +G +T+ L Y G+ ++ G GA+S + Sbjct: 386 GNAQQEKP-RFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQA 444 Query: 400 QAKYHNGKNLKGYSTSLKYAKALGD-NANLQLIGYRFNSEDYIDYADFTY---------- 448 + + G S Y K+L + N+QL+GYR+++ Y ++AD TY Sbjct: 445 NSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIET 504 Query: 449 -----------NSYSFIRNRPKQRYESIVTYQLPEKGMFLNFSAWKEDYWD-NYNEVGAN 496 Y + + + + VT QL L S + YW + + Sbjct: 505 QDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTST-LYLSGSHQTYWGTSNVDEQFQ 563 Query: 497 LSLTKSFDQITMTLNGGYSRLQNM-DADYNVGLSLSVPLSLFDKTH--------YSFSNV 547 L +F+ I TL+ ++ D + L++++P S + ++ + ++ Sbjct: 564 AGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSM 623 Query: 548 NYDRRTGTSMNTGISGMI--NQRLSYNASVNQTRDTIG-----GTLSASYLFDWMQTSAT 600 ++D + G+ G + + LSY+ G G + +Y + + Sbjct: 624 SHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIG 683 Query: 601 YSQTGKNSSTSLQLGGSVIGVPEGGIIFTPVKNDQLAIVQMKDVPGVMFNGSLPG--DKY 658 YS + + G V+ G+ ND + +V+ D Sbjct: 684 YSHSDDIKQLYYGVSGGVLAHA-NGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR 742 Query: 659 GRAVIP-LTAYNNNTISVNAEKLPKNIELTDNAINVTPTGNAIIYKNVKFK-KINTYVVK 716 G AV+P T Y N ++++ L N++L + NV PT AI+ +FK ++ ++ Sbjct: 743 GYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVR--AEFKARVGIKLLM 800 Query: 717 LYGKNGYVVPMGSIAKNTQGKEVGYVNNGG-ILLMNLETHDE-----GVISLDQCQFNTQ 770 N +P G++ + + G V + G + L + + G C N Q Sbjct: 801 TLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQ 860
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 64.5 bits (157), Expect = 2e-13 Identities = 56/314 (17%), Positives = 103/314 (32%), Gaps = 82/314 (26%) Query: 66 ITPQVTGIVTEVTDKNNQLIQKGEVLFKLDPVR------------YQARVD--RLQA--- 108 I P IV E+ K + ++KG+VL KL + QAR++ R Q Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 109 ------------------------DLMTATHNIK----TLRAQLTEAQANTTQVSAERDR 140 +++ T IK T + Q + + N + AER Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 141 LFKNYQRY----------LKGSQAAVNPFS---------ERDIDDARQNF---LAQDALV 178 + RY L + ++ + E +A +Q + Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 179 KGSVAE----QAQIQSQLDSMVNGE----QSQIVSLRAQLTEAKYNLEQTVIRAPSNGYV 230 + + + + + + I L +L + + + +VIRAP + V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 231 TQVLIR-PGTYAAALPLRPVMVFIPEQKRQIV-AQFRQNSLLRLKPGDDAEVVFNALPGQ 288 Q+ + G +MV +PE V A + + + G +A + A P Sbjct: 339 QQLKVHTEGGVVT--TAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYT 396 Query: 289 VFH---GKLTSILP 299 + GK+ +I Sbjct: 397 RYGYLVGKVKNINL 410
>PF03895#Serum resistance protein DsrA. Length = 79 Score = 63.7 bits (155), Expect = 1e-14 Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 1472 ESKLSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGESAVALGV-SMVSANGRWVYKLQ 1530 +L G+A+ A++ L Q G + S G Y ++A+A+GV S ++ + Sbjct: 2 SKELQTGLANQSALSMLVQPNGVGKTSVSAAVGGYRDKTALAIGVGSRITDRFTAKAGVA 61 Query: 1531 GSTNSQGEYSAALGAGIQW 1549 +T + G S G ++ Sbjct: 62 FNTYN-GGMSYGASVGYEF 79
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.4 bits (66), Expect = 0.020 Identities = 20/87 (22%), Positives = 30/87 (34%), Gaps = 13/87 (14%) Query: 8 MTVI---GAGSYGTALAITLARNGHEVVLWGHD---PEHIATLERDRCNAAFLPDVPFPD 61 M + AG G ++ L GH+VV G D + +L++ R P F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVV--GIDNLNDYYDVSLKQARLELLAQPGFQF-- 56 Query: 62 TLHLESDLATALAASRNILVVVPSHVF 88 + DLA + VF Sbjct: 57 ---HKIDLADREGMTDLFASGHFERVF 80
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 235 bits (600), Expect = 1e-82 Identities = 87/153 (56%), Positives = 117/153 (76%), Gaps = 4/153 (2%) Query: 3 EQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRV 62 Q + QIQRIY KD+SFEAPN PH+FQ+DW+P++ DL T + Q+ DD+YEV L + Sbjct: 12 TQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQVGDDLYEVCLNI 71 Query: 63 TVTASLGEE--TAFLCEVQQGGIFSIAGIEGTQMAHCLGAYCPNILFPYARECITSMVSR 120 +V ++ AF+CEV+Q G+F+I+G+E QMAHCL + CPN+LFPYARE ++S+V+R Sbjct: 72 SVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPYARELVSSLVNR 131 Query: 121 GTFPQLNLAPVNFDALFMNYL--QQQAGEGTEE 151 GTFP LNL+PVNFDALFM+YL Q+QA + TEE Sbjct: 132 GTFPALNLSPVNFDALFMDYLQRQEQAEQTTEE 164
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 36.2 bits (83), Expect = 2e-04 Identities = 51/223 (22%), Positives = 74/223 (33%), Gaps = 22/223 (9%) Query: 52 RAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNKQIDEMNASIAKLEQQKA 111 R + +++ R A K +EA RE T QL E A E+ KA Sbjct: 131 RLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALSEEAKA 190 Query: 112 ---AQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYFGYLNQARQETIAQLKQ 168 AQ++ AAQ + GE + LS AR + L Sbjct: 191 VEIAQKKLSAAQSEVVKMDGEIKTLNSRLSS---------------SIHARDAEMKTLAG 235 Query: 169 TREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALSERKKTLAGLESSIQQGQQQLSE 228 R E+A A+ +E + L + R++ AG +Q Q SE Sbjct: 236 KRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASE 295 Query: 229 LRANESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEATRK 271 R N R+ I + + A R A R + E K Sbjct: 296 TRIN--RINADITQIQKAIS--QVSNNRNAGIARVHEAEENLK 334
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 105 bits (264), Expect = 2e-28 Identities = 78/348 (22%), Positives = 128/348 (36%), Gaps = 67/348 (19%) Query: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKD--------------GTKFVNLVDLDI 47 +VTG AGFIG ++ K L + G ++ +DNL D +D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 48 ADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSK-------EL 100 AD + + + A F E +F + +Y ++N + Y+ + Sbjct: 62 ADR----EGMTDLFASGHF---ERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNI 109 Query: 101 LHYCLEREIP-LLYASSAATYGGRTSD-FIESREYEKPLNVYGYSKFLFDEYVRQILPEA 158 L C +I LLYASS++ YG F + P+++Y +K + Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 159 NSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA 218 G R+F VYGP + MA F + G+S ++ KRDF Y+ D+A Sbjct: 170 GLPATGLRFFTVYGPWG--RPDMA--LFKFTKAMLEGKSIDVY-NYGKMKRDFTYIDDIA 224 Query: 219 DVNL------------WFLENGVSG-------IFNLGTGRAESFQAVADATLAY-HKKGQ 258 + + W +E G ++N+G A + + Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 259 IEYIPFPDKLKGRYQAFTQADLTNLRAA-GYDKPFKTVAEGVTEYMAW 305 +P G T AD L G+ P TV +GV ++ W Sbjct: 285 KNMLPLQ---PGDVL-ETSADTKALYEVIGF-TPETTVKDGVKNFVNW 327
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 51.2 bits (122), Expect = 3e-10 Identities = 40/182 (21%), Positives = 70/182 (38%), Gaps = 9/182 (4%) Query: 1 MAEK-QTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMF 59 MA K + + R+ IL AL L S G + ++A + GV+ A+Y HF K+ +F Sbjct: 1 MARKTKQEAQETRQHILDV-ALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 60 DSLIEFIEDSLITRIN-LILKDEKDTTARLRLIVLLLL---GFGERNPGLTRILTGHALM 115 + E E ++ K D + LR I++ +L ER L I+ Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 116 F-EQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYA-TDETLLASQILAFCEGMLSRF 173 E +Q L ++ Q L+ + A A + + G++ + Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHC-IEAKMLPADLMTRRAAIIMRGYISGLMENW 178 Query: 174 VR 175 + Sbjct: 179 LF 180
>SECA#SecA protein signature. Length = 901 Score = 41.8 bits (98), Expect = 9e-06 Identities = 39/129 (30%), Positives = 57/129 (44%), Gaps = 18/129 (13%) Query: 233 NLSMLALRAGAQRFHAQPLSANDALKNKLLAALPFKPTGAQARVAAEIERDM-ALDVPMM 291 LS L+ F A+ L + L+N + A A R A++ M DV ++ Sbjct: 37 KLSDEELKGKTAEFRAR-LEKGEVLENLIPEAF------AVVREASKRVFGMRHFDVQLL 89 Query: 292 ---RLVQGDV-----GSGKTLVAALAA-LRAIAHGKQVALMAPTELLAEQHANNFRNWFA 342 L + + G GKTL A L A L A+ GK V ++ + LA++ A N R F Sbjct: 90 GGMVLNERCIAEMRTGEGKTLTATLPAYLNALT-GKGVHVVTVNDYLAQRDAENNRPLFE 148 Query: 343 PLGIEVGWL 351 LG+ VG Sbjct: 149 FLGLTVGIN 157
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 32.9 bits (75), Expect = 0.003 Identities = 78/491 (15%), Positives = 168/491 (34%), Gaps = 73/491 (14%) Query: 7 RQNRLLRFLLPRREYTTIVTIAGYLNVSEKTIQRDLRLLEQWL-GQWRINVEKRAGAGVM 65 + +L+ + I +A ++ + L + + ++KR M Sbjct: 45 SKCQLVVLFF-KTSSLPITEVAEKTGLTFLQLNHYCEELNAFFPDSLSMTIQKR-----M 98 Query: 66 LSAENIADLLHLDHLLGAECEEIDGVMNNARRVKIASQLLSETPNETSISKLSERYFISG 125 + H ++ + + ++ +++ + L+ + ++ + +F+S Sbjct: 99 I-------SCQFTHP--SKETYLYQLYASSNVLQLLAFLIKNGSHSRPLTDFARSHFLSN 149 Query: 126 ASIVNDLRVIESWLAPLGLSLIRSPSGTHIEGSEGQVRQAMALLINGIINHNEPQGVVYS 185 +S + L L L S I G E ++R +ALL G+ Sbjct: 150 SSAYRMREALIPLLRNFELKL----SKNKIVGEEYRIRYLIALL-------YSKFGIKVY 198 Query: 186 RLDPGSYKALVHYFGEEEVLFVQSLLLDMENELSWSLGEPYYVNIFTHILIMMYRNTHGN 245 L K ++H F L S L LS E + F IL+ + H Sbjct: 199 DLTQQD-KNIIHSF-----LSHSSTHLKTSPWLS----ESFS---FYDILLALSWKRHQF 245 Query: 246 ALSREEDQTRQYDENIF---NVASQMIHKIEQRIAHTLPDDEVWFIYQ-YIISSGVAIDG 301 +++ + + Q + +F ++ IE ++ ++Y YI ++ Sbjct: 246 SVTIPQTRIFQQLKKLFVYDSLKKSSRDIIETYCQLNFSAGDLDYLYLIYITANNSFASL 305 Query: 302 Q---KDVSIISHMQASNEA-RLITWRLITVFSDIVD---------CDFSEDSALYDGLMV 348 Q + + + N+ RL+ +IT+ ++ + FS+ S L++ + Sbjct: 306 QWTPEHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSK-SFLFN--LQ 362 Query: 349 HIKPLINRLNYRIHIRNPLLEDIKAELADVWRLTQYVVNQVFKTWGENAVSEDEVGYLTV 408 H P N + N L + + W + K G+ ++ Sbjct: 363 HFIPETNLFVSPYYKGNQKLYTSLKLIVEEW---------MAKLPGKRYLNHKHFHLFCH 413 Query: 409 HFQAAMERQIARKRVLLVCSTGIGTSHLLKSRILRAFPEWTI---VDVISAANLSQVLPD 465 + + + V+ V S I +HLL R F + +I + N+ Q+ Sbjct: 414 YVEQILRNIQPPLVVVFVASNFI-NAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDL 472 Query: 466 NIELIISTINL 476 +L+I+ L Sbjct: 473 KPDLVITHSQL 483
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 27.8 bits (61), Expect = 0.006 Identities = 10/34 (29%), Positives = 19/34 (55%), Gaps = 4/34 (11%) Query: 52 QLYIPHIFSYLNE----DIDFVLNELKAKGLCRD 81 +LY P +F Y+N+ + + LK +G+ +D Sbjct: 258 ELYAPDMFEYMNKLEKGGFEKISESLKKEGVEKD 291
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 25.8 bits (56), Expect = 0.036 Identities = 12/31 (38%), Positives = 17/31 (54%) Query: 18 VACAWLTVCERQHRYPHLTLESLEAAIAAEL 48 VAC W+ VCE ++ PH +E I+ L Sbjct: 135 VACFWVDVCEDKNATPHSPQHRMETLISQAL 165
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.6 bits (95), Expect = 7e-06 Identities = 71/391 (18%), Positives = 129/391 (32%), Gaps = 33/391 (8%) Query: 20 LLVAFLTGIAGALQTPTLSIFLADELKARPIM--VGFFFTGSAIMGILVSQFLARHSDKQ 77 L L + L P L L D + + + G A+M + L SD+ Sbjct: 11 LSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF 70 Query: 78 GDRKLLILLCCLFGVLACTLFAWNRNYFILLSTGVLLSSFASTANPQMFALAREHADRTG 137 G R ++L+ + + A ++L ++ A AD T Sbjct: 71 GRR-PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV----AGITGATGAVAGAYIADITD 125 Query: 138 RET-VMFSTFLRAQISLAWVIGPPLAYELAMGFSFKVMYLTAAIAFVVCGLIVWLFLP-- 194 + F+ A V GP L + GFS + AA + L LP Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMG-GFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 195 --SIQRNIPVVT-QPVEILPSIHRKRDTRLLFVVCSMMWAANNLYMINMPLFIIDELHLT 251 +R + P+ L V +M + +F D H Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWD 244 Query: 252 DKLAGEMI-GIAAGLEIPMMLIAGYYMKRIGKRLLMLIAIVSGMCFYASVLMATTPAIEL 310 G + + +I G R+G+R +++ +++ Y +L+A + Sbjct: 245 ATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGY--ILLAFATRGWM 302 Query: 311 ELQILNAIFLGILCGIGMLYFQDLMPEKI---------GSATTLYANTSRVGWIIAGSVD 361 + L GIGM Q ++ ++ GS L + TS VG ++ ++ Sbjct: 303 ---AFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIY 359 Query: 362 GIMVEIWSYHALFWLAIGMLGIAMICLLFIK 392 + W+ W I + ++CL ++ Sbjct: 360 AASITTWNG----WAWIAGAALYLLCLPALR 386 Score = 32.1 bits (73), Expect = 0.004 Identities = 18/102 (17%), Positives = 34/102 (33%) Query: 17 AAFLLVAFLTGIAGALQTPTLSIFLADELKARPIMVGFFFTGSAIMGILVSQFLARHSDK 76 AA + V F+ + G + IF D +G I+ L + Sbjct: 213 AALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAA 272 Query: 77 QGDRKLLILLCCLFGVLACTLFAWNRNYFILLSTGVLLSSFA 118 + + ++L + L A+ ++ VLL+S Sbjct: 273 RLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGG 314
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 100 bits (249), Expect = 2e-29 Identities = 34/164 (20%), Positives = 69/164 (42%), Gaps = 5/164 (3%) Query: 5 NLDLEENKEIASKFERALGMGATLAELHGITPDTLEGVYAYAYNFYEKGRLDEAELFFKF 64 + + +E E L G T+A L+ I+ DTLE +Y+ A+N Y+ G+ ++A F+ Sbjct: 2 QQETTDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQA 61 Query: 65 LCIYDFQNYNYLKGYAAVCQLKKDYQKAFDMYHICLMLSPDNDFSLVYYMGQCQMGLKNI 124 LC+ D + + G A Q Y A Y ++ + ++ +C + + Sbjct: 62 LCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIK-EPRFPFHAAECLLQKGEL 120 Query: 125 KMATELFNT----VVTYSQNEKIKEMATTYLELLTANSEEEVQT 164 A + ++ +++ ++ LE + E E + Sbjct: 121 AEAESGLFLAQELIADKTEFKELSTRVSSMLEAIKLKKEMEHEC 164
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 115 bits (288), Expect = 4e-29 Identities = 117/544 (21%), Positives = 227/544 (41%), Gaps = 37/544 (6%) Query: 60 NKPMLAPPTIQVSDSDNATTAKTNDARLTMILGNLTGIADQDITTRLHNNLDSTLLRHEM 119 N L PPT + ++ + +LT++LG L + ++L + L E Sbjct: 64 NTVGLKPPTDAAREKLSS------EGQLTLLLGKLMTLLGDVSLSQLESRLAVWQAMIES 117 Query: 120 AHNKFRELSDAYSSSLDDAQKADDIMHQANNNYNAVDKKVQSLEKKVNTLNQELSQLQPG 179 ++S + ++L +AQ+A D+ + + + KK+ +L L P Sbjct: 118 QKEMGIQVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAATKKLTQAQNKLQSLDPA 177 Query: 180 DPQYNKVLTQKNAAEKTLTLSLQKKSLAEKSLNTAIMDADAAIGQSMEIFDEIQQQEQIN 239 DP Y + A K T + + A + A DA A ++ I + Q Sbjct: 178 DPGYAQAEAAVEQAGKEATEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQ---GTA 234 Query: 240 NFTTNICLTQENQKNRNATATFILLITSVMEVIGDTNCDSIKNQSEVMKEINHVRENKLN 299 N + ++Q Q N + A +L+ +E++G +S++N + + R+ ++ Sbjct: 235 NAASQNQVSQGEQDNLSNVARLTMLMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEME 294 Query: 300 ETARKYTTTTKVLKIVNECVTVVTFAVSAVLIVVGLLAAVPSGGSSIAGALALIGGIAGA 359 + + ++ T+ + N + + + A+L +V ++AAV +GG+S+A A A Sbjct: 295 KKSAEFQEETRKAEETNRIMGCIGKVLGALLTIVSVVAAVFTGGASLALA---------A 345 Query: 360 VVLGVDITCQIALGTTATGWILGKVVEGLSAAIKTVDPTL-LAITALLDVIGVDQDTIEL 418 V L V + +I T +I + + +K + + AIT L+ +GVD+ T E+ Sbjct: 346 VGLAVMVADEIVKAATGVSFIQQALNPIMEHVLKPLMELIGKAITKALEGLGVDKKTAEM 405 Query: 419 VKSIYASAAASIVMATVMIGAAVICSVAIGAVVSALSKTAAEEVTKEITSTIK---STIE 475 SI + A+I M V++ AV+ A + +ALSK E + K + + +K Sbjct: 406 AGSIVGAIVAAIAMVAVIVVVAVVGKGAAAKLGNALSKMMGETIKKLVPNVLKQLAQNGS 465 Query: 476 SIINSVSKNIIKVLDSVCS--VLQTSAVVLKLIAKISNGLEKIGLLICAIATSTMNC--- 530 + + I L +V S LQT+A+ +L + N L K+ L + T+ + Sbjct: 466 KLFTQGMQRITSGLGNVGSKMGLQTNALSKEL---VGNTLNKVALGMEVTNTAAQSAGGV 522 Query: 531 -------FVAGNSADMAILQQDMSNLSKTREQMLSVLQRVDKTVEQEVSQMVRVLQHRTE 583 + AD + + M + + +Q + + K + M +Q + Sbjct: 523 AEGVFIKNASEALADFMLARFAMDQIQQWLKQSVEIFGENQKVTAELQKAMSSAVQQNAD 582 Query: 584 ALKF 587 A +F Sbjct: 583 ASRF 586
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.9 bits (80), Expect = 7e-04 Identities = 61/372 (16%), Positives = 133/372 (35%), Gaps = 32/372 (8%) Query: 49 FNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAIC 108 N++ D+ + + + F +T+ +G + +D K+ L F +I++ C Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIIN--C 90 Query: 109 MLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTI----TKWTPRRKRGTFLGFW 164 +G SL +M + F Q G + + + ++ P+ RG G Sbjct: 91 FGSVIGFVGHSFFSLLIM------ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 165 NISHNLGGA-----GAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPES 219 +G G +YL +I + P ++ L+ + ++ D Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGI 204 Query: 220 YGLGKAEELFGEEISEEDKETESTDMTKWQIFVEYVLK--NKVIWLLCFANI-FLYVVRI 276 + F + + + IFV+++ K + + NI F+ V Sbjct: 205 ILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLC 264 Query: 277 GIDQWSTVYAFQELKLSKAVAIQGFTLFEAG------ALVGTLLWGWLSDLANGRRG--L 328 G + TV F + + + E G + +++G++ + RRG Sbjct: 265 GGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLY 324 Query: 329 VACIALALIIA---TLGVYQHASNQYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIG 385 V I + + T ++ ++ + +F LG L F ++ + + ++A G Sbjct: 325 VLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEA-G 383 Query: 386 AADGIKGTFAYL 397 A + ++L Sbjct: 384 AGMSLLNFTSFL 395
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 40.2 bits (94), Expect = 1e-05 Identities = 65/408 (15%), Positives = 137/408 (33%), Gaps = 60/408 (14%) Query: 29 RHILLTIWLGYALFY--FTRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSG 86 RH + IWL F+ N ++P+I + + + T F +T+ + V G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 87 IVSDRSNARYFMGIGLIATGIINILFGFSTSLWAFAVLWVLNAFFQGWGS---PVCARLL 143 +SD+ + + G+I +++ S F L ++ F QG G+ P ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHS---FFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 144 TAWY-SRTERGGWWALWNTAHNVGGALIPIVMAASALHYGWRAGMMIAGCMAIVVGIFLC 202 A Y + RG + L + +G + P + A + W ++ M ++ + Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPF- 184 Query: 203 WRLRDRPQALGLPAVGEWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLV 262 + L +I G L I+ + Y VL Sbjct: 185 --------LMKLLKKEVRIKGHFDIK----GIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 263 YVV-----RAAINDWGNLYMSETLGVDLVTANTAVTMFELGGFI-----------GALVA 306 +++ R + + + + + + + + + GF+ A Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 307 GWGSDKLFNGNRGPMNLIFAAGILL-SVGSLWLMPFASYVMQATCFFTIGFFVFGPQMLI 365 GS +F G + + GIL+ G L+++ + + F T F + + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL-SVSFLTASFLLETTSWFM 351 Query: 366 ---------GMAAAECS---------HKEAAGAATGFVGLFAYLGASL 395 G++ + ++ AGA + ++L Sbjct: 352 TIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>PF06580#Sensor histidine kinase Length = 349 Score = 40.2 bits (94), Expect = 1e-05 Identities = 32/166 (19%), Positives = 68/166 (40%), Gaps = 18/166 (10%) Query: 341 KQSGQLIEHLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWR 400 ++ +++ LS + +R L RQ+ +L + + ++L L++ Sbjct: 191 TKAREMLTSLS----ELMRYSLRYSNARQV---SLADELTVVDSYLQLASIQFEDRLQFE 243 Query: 401 IDESALSENQRVTLFRVCQEGLNNIVKHA-----DASAVTLQGWQQDERLMLVIEDDGSG 455 + + +V + Q + N +KH + L+G + + + L +E+ GS Sbjct: 244 NQINPAIMDVQVPPM-LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL 302 Query: 456 LPPDSGQ-HGFGLTGMRERVTALGG---TLTISCLHG-TRVSVSLP 496 ++ + G GL +RER+ L G + +S G V +P Sbjct: 303 ALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 2e-13 Identities = 29/174 (16%), Positives = 59/174 (33%), Gaps = 20/174 (11%) Query: 2 ITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDIS 61 T+ + DD +R+ Q L V + + + + D+ MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLELLSQLPK---GMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATG 118 +LL ++ K + +++S ++ +A GA +L K ELI + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR---- 117 Query: 119 GCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQG---MAVKEIAAELGLSPKTV 169 A+ R L + + + + + A L + T+ Sbjct: 118 --------ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 765 bits (1978), Expect = 0.0 Identities = 329/867 (37%), Positives = 489/867 (56%), Gaps = 60/867 (6%) Query: 15 CLIFSQSLMAEVSV------FNPALLEIDHQSGVDIRQFNRANLMPPGVYSVDIFINGKM 68 L + + A+ + FNP L D Q+ D+ +F +PPG Y VDI++N Sbjct: 29 RLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGY 88 Query: 69 FERQDVTFVQDNPDADLHACFVAIKKTLTTFGVKVDALKSLNDVDETVCIDPGPRIEGSS 128 +DVTF + + + C L + G+ ++ +N + + C+ I ++ Sbjct: 89 MATRDVTFNTGDSEQGIVPCLTR--AQLASMGLNTASVSGMNLLADDACVPLTSMIHDAT 146 Query: 129 WQFDSDKLQLNISIPQIYMDAMAYDYISPSRWDEGINALTINYDFSGSHTLRSDYGSQET 188 Q D + +LN++IPQ +M A YI P WD GINA +NY+FSG+ + + Sbjct: 147 AQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSV--QNRIGGNS 204 Query: 189 DTSYLNLRNGLNIGPWRLRNYSTLN------TTDGSAEYNSISTWIQRDIAALRSQIMIG 242 +YLNL++GLNIG WRLR+ +T + ++ ++ I+TW++RDI LRS++ +G Sbjct: 205 HYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLG 264 Query: 243 DTWTASDIFDSTQIRGARLYTDNDMLPASQNGFAPVVRGIAKSNATVIIRQNGYVIYQSA 302 D +T DIFD RGA+L +D++MLP SQ GFAPV+ GIA+ A V I+QNGY IY S Sbjct: 265 DGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNST 324 Query: 303 VPQGAFEITDLNTASTGGDLDVTIKEEDGSEQRFTQPYASLAILKREGQTDVDVSVGELR 362 VP G F I D+ A GDL VTIKE DGS Q FT PY+S+ +L+REG T ++ GE R Sbjct: 325 VPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYR 384 Query: 363 DEDG--FTPDVIQAQILHGFPYGFTLYGGMQAAEKYGSAALGVGKDLGALGAISFDVTHA 420 + P Q+ +LHG P G+T+YGG Q A++Y + G+GK++GALGA+S D+T A Sbjct: 385 SGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQA 444 Query: 421 RAKFSHDDTETGQSYRFLYSKRFDDTDTSLRLVGYRYSTEGYYTLNEWASRRNN------ 474 + D GQS RFLY+K +++ T+++LVGYRYST GY+ + R N Sbjct: 445 NSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIET 504 Query: 475 -----------PEDFWETGNRRSRVEGTLTQSLGRDYGNLYLTLSRQQYWHTDDVERLMQ 523 + + N+R +++ T+TQ LGR LYL+ S Q YW T +V+ Q Sbjct: 505 QDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSNVDEQFQ 563 Query: 524 FGYSSSWKRLSWNVSWSYSNTARQGTGNNHASDNTSEQIYMLSLSVPLSGW--------W 575 G +++++ ++W +S+S + A +Q+ L++++P S W W Sbjct: 564 AGLNTAFEDINWTLSYSLTKN---------AWQKGRDQMLALNVNIPFSHWLRSDSKSQW 614 Query: 576 GNSYATYSVSQNDNSGSSHQLGLSGTALERNNLSWNLMQSYNSHDDEVGGN---MSLTYD 632 ++ A+YS+S + N ++ G+ GT LE NNLS+++ Y D G+ +L Y Sbjct: 615 RHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYR 674 Query: 633 GTYGTVNGSYNYSQNSQRLNYGIRGGILAHSEGVTLSQELGETIALVKAPGAAGLEIDNM 692 G YG N Y++S + ++L YG+ GG+LAH+ GVTL Q L +T+ LVKAPGA +++N Sbjct: 675 GGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQ 734 Query: 693 RGAATDWRGYTVKTQLNPYDENRVAISDNYFSKSNIELDNTVVTMVPTRGAVVKAEFVTR 752 G TDWRGY V Y ENRVA+ N + N++LDN V +VPTRGA+V+AEF R Sbjct: 735 TGVRTDWRGYAVLPYATEYRENRVALDTNTLA-DNVDLDNAVANVVPTRGAIVRAEFKAR 793 Query: 753 VGYRVLFRVAGTKGKPAPFGAIATVQNTSSADSGIVGDLGELYLSGLPEKGQVMLSWGEN 812 VG ++L + KP PFG A V + SS SGIV D G++YLSG+P G+V + WGE Sbjct: 794 VGIKLLMTLTH-NNKPLPFG--AMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEE 850 Query: 813 AATTCTFDYSISIPESESGLIEQGVTC 839 C +Y + + L + C Sbjct: 851 ENAHCVANYQLPPESQQQLLTQLSAEC 877
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.048 Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 10/80 (12%) Query: 367 LGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTT 426 LGD + D V + AG+ N G DV T G AT A T Sbjct: 616 LGDGD--DKVFLSAGSA--NIYAGK------GHDVVYYDKTDTGYLTIDGTKATEAGNYT 665 Query: 427 VTRNVGENALAISRVPQTQK 446 VTR +G + + V + Q+ Sbjct: 666 VTRVLGGDVKVLQEVVKEQE 685
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 0.001 Identities = 40/196 (20%), Positives = 62/196 (31%), Gaps = 51/196 (26%) Query: 170 KHALERPKPTDAVSRALQHDLSDVVGQEQG----KRGLEITAAGGHNLLLIGPPGTGKTM 225 AL PK + D +VG+ R L L++ G GTGK + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKEL 175 Query: 226 LASRINGLLPDLSNEEALESAAILSLVNAESVQKQWRQRPFRSPHHSA--------SLTA 277 +A ++ R PF + + +A L Sbjct: 176 VARALHDYGK-------------------------RRNGPFVAINMAAIPRDLIESELFG 210 Query: 278 MVGG---GAIP-GPGEISLAHNGVLFLDEL----PEFERRTLDALREPIESGQIHLSRTR 329 G GA G A G LFLDE+ + + R L L++ G+ Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQ----GEYT--TVG 264 Query: 330 AKITYPARFQLVAAMN 345 + + ++VAA N Sbjct: 265 GRTPIRSDVRIVAATN 280
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.005 Identities = 11/71 (15%), Positives = 31/71 (43%) Query: 14 AKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTSSGSKGQNAPKDPRIGSKTPIP 73 +K + + EE+++ + R+ + +R ++++ + + ++G P P Sbjct: 827 SKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCP 886 Query: 74 LGVTEKVTKQH 84 G +K + H Sbjct: 887 CGSGKKYKQCH 897
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 603 bits (1556), Expect = 0.0 Identities = 206/478 (43%), Positives = 300/478 (62%), Gaps = 11/478 (2%) Query: 4 MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALASKTPDVLLSDIRMPGM 63 M + V DDD++IR VL +AL+ AG N A + +A+ D++++D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 64 DGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAIS 123 + LL +IK+ P LPV++M+A + A+ A ++GA+DYLPKPFD+ E + ++ RA++ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 124 HYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHA 183 + + ++G + AMQ+++R++ RL ++ ++++I GESGTGKELVA A Sbjct: 121 EPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 184 LHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDE 243 LH + R PF+A+NMAAIP+DLIESELFGHEKGAFTGA T GRFEQA+GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 244 IGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVQEGKFREDLFHR 303 IGDMP+D QTRLLRVL G++ VGG P++ DVRI+AAT+++L+Q + +G FREDL++R Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 304 LNVIRVHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETEAALTRLAWPGNVRQL 363 LNV+ + LPPLR+R EDIP L RHF+Q A +E G++ K E + WPGNVR+L Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 364 ENTCRWLTVMAAGQEVLIQDLPGELFESTVAESTSQMQPDSWATLLAQWADRALRS---- 419 EN R LT + + + + EL + S + ++Q + +R Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 420 -----GHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME 472 L E+E L+ AL T+G++ +AA LLG RNTL +K++ELG+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 180 bits (458), Expect = 4e-51 Identities = 97/445 (21%), Positives = 170/445 (38%), Gaps = 81/445 (18%) Query: 4 KLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQE--RVMDSNDLEKERGITILAKNT 61 K+ NI ++AHVD GKTTL + LL SG + D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 62 AIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAYGL 121 + +W + ++NI+DTPGH DF EV R +S++D +L++ A DG QTR + G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 122 KPIVVINKVDRPGARPDWVVDQVFD-------------LFVNLDATDEQLD--------- 159 I INK+D+ G V + + L+ N+ T+ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 160 --------------------------------FPIVYASALNGIAGLDHEDMAEDMTPLY 187 FP+ + SA N I G+D+ L Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNI-GIDN---------LI 231 Query: 188 QAIVDHVPAPDVDLDGPFQMQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTR 247 + I + + ++ +++Y+ + R+ G + V I + E Sbjct: 232 EVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-- 289 Query: 248 NAKVGKVLGHLGLERIETDLAEAGDIVAITGLGELNISDTVCDTQNVEALPALSVDEPTV 307 K+ ++ + E + D A +G+IV + L ++ + DT+ + + P + Sbjct: 290 --KITEMYTSINGELCKIDKAYSGEIVILQNEF-LKLNSVLGDTKLLPQRERIENPLPLL 346 Query: 308 SMFFCVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGELHLS 367 + + D L LR +S G++ + Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPL---------LRYYVDSATHEIILSFLGKVQME 397 Query: 368 VLIENMRRE-GFELAVSRPKVIFRE 391 V ++ + E+ + P VI+ E Sbjct: 398 VTCALLQEKYHVEIEIKEPTVIYME 422 Score = 32.5 bits (74), Expect = 0.005 Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 398 EPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMT 457 EPY + + +++ + ++ + V L IP+R + +RS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDLTF 595 Query: 458 MTSGTGLLYSTFSHY 472 T+G + + Y Sbjct: 596 FTNGRSVCLTELKGY 610
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 9e-24 Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 2/117 (1%) Query: 3 KILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLL-DDSIDLLLLDVMMPKKNGID 61 IL+ DDD + ++L + L G++V + + + DL++ DV+MP +N D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 TLKALRQTH-QTPVIMLTARGSELDRVLGLELGADDYLPKPFNDRELVARIRAILRR 117 L +++ PV++++A+ + + + E GA DYLPKPF+ EL+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 26.2 bits (57), Expect = 0.023 Identities = 6/22 (27%), Positives = 14/22 (63%) Query: 28 ETAVVKMVKENKLPVIELRDPS 49 E+ +K+V++ + VI +P+ Sbjct: 849 ESKKIKVVEDKPVEVINESEPN 870
>SECA#SecA protein signature. Length = 901 Score = 28.3 bits (63), Expect = 0.016 Identities = 11/72 (15%), Positives = 26/72 (36%) Query: 6 VEKQPAAMRRIIGKHLAVPRWQDTCDYYNQMMERERLTVCFHAQLKQRHATMRFEEMNDV 65 + ++ L + W D ++ RER+ +++ + E M Sbjct: 703 IPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHF 762 Query: 66 ERERLVCAIDEL 77 E+ ++ +D L Sbjct: 763 EKGVMLQTLDSL 774
>PF06872#EspG protein Length = 398 Score = 29.3 bits (65), Expect = 0.014 Identities = 24/95 (25%), Positives = 37/95 (38%), Gaps = 5/95 (5%) Query: 122 PPYMFTEEVALAAMRAHAAGESVDTRLLTETIELTATADMPDEVRAKLHKITGLFLRDAG 181 P M T ++ A+ A S+D I +T +++ V + TG+ + Sbjct: 298 PALMLTHV-RISQASAYNAQRSLDMPNACINISITQSSEGSIHVTSH----TGVLIMAPE 352 Query: 182 DAAGALAHLQRATQLDCQAGVKKEIERLERELKPK 216 D L L T + GVK E + R LK K Sbjct: 353 DRPNQLGMLTNRTSYEVPPGVKCEPNEMARMLKAK 387
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 28.2 bits (62), Expect = 0.016 Identities = 13/35 (37%), Positives = 18/35 (51%), Gaps = 2/35 (5%) Query: 105 SISLMLTERTLVSEVDGALH--VKNIPEPPPPEPV 137 ++ + RTL E DG V N+ PPPP P+ Sbjct: 340 ILTQLCAARTLAYEGDGYRRAPVNNMMPPPPPPPM 374
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.3 bits (73), Expect = 0.008 Identities = 28/144 (19%), Positives = 53/144 (36%), Gaps = 4/144 (2%) Query: 36 RETQKSLRELNGQASRIEGFRKTSAQLAVTGHALEKARQEAEALATQFKNTERPTRAQAK 95 + + ++ +++I+ A LA LEKA + A +T + A+ Sbjct: 197 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKA 256 Query: 96 VLE----SAKRAAEDLQAKYNRLTDSVKRQQRELAVVGINTRNLAHDEQGLKNRISETTA 151 LE ++A E + +K + E A + +L H Q L Sbjct: 257 ALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRR 316 Query: 152 QLNRQRDALARVSAQQAKLNAVKQ 175 L+ R+A ++ A+ KL + Sbjct: 317 DLDASREAKKQLEAEHQKLEEQNK 340
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.018 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 3/36 (8%) Query: 49 TPKNILMIGPTGVGKTEIAR---RLAKLANAPFIKV 81 T +++ G +G GK +AR K N PF+ + Sbjct: 159 TDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.0 bits (98), Expect = 2e-06 Identities = 32/155 (20%), Positives = 64/155 (41%), Gaps = 5/155 (3%) Query: 114 LTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSR 173 + +QAD+ P+ E+ ++ P + +AE + Q+S+ Sbjct: 992 VDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK--QESK 1049 Query: 174 TTEQSWQQQT-RTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHTTAQSKPQQAAPVARA 232 T E++ Q T T+Q V + + + A+TQ + T ++ ++ A V + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 233 ADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQ 267 A T + ++ + Q + EQ+ETV+ Q Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQ--EQSETVQPQ 1142
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 360 bits (925), Expect = e-128 Identities = 171/262 (65%), Positives = 203/262 (77%), Gaps = 6/262 (2%) Query: 30 WLHQSLNVIGRTDSRFGPRLTNDLYPEYTVAGRKDWFDFYGYVDLPKFFGVGSHYDVGIW 89 W HQS+NV+G +RFGP++ ND Y EY +KDWFDFYGY+D P FFG G+ GIW Sbjct: 34 WWHQSVNVVGSYHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYIDAPVFFG-GNSTAKGIW 92 Query: 90 DEGSPLFTEIEPRFSIDKLTGLNLAFGPFKEWFIANNYVYDMGDNQSSRQSTWYMGLGTD 149 ++GSPLF EIEPRFSIDKLT +L+FGPFKEW+ ANNY+YDMG N S QSTWYMGLGTD Sbjct: 93 NKGSPLFMEIEPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNDSQEQSTWYMGLGTD 152 Query: 150 IDTGLPIKLSANIYAKYQWQNYGAANENEWDGYRFKIKYSIPLTHLFGGRLVYNSFTNFD 209 IDTGLP+ LS N+YAKYQWQNYGA+NENEWDGYRFK+KY +PLT L+GG L Y FTNFD Sbjct: 153 IDTGLPMSLSLNVYAKYQWQNYGASNENEWDGYRFKVKYFVPLTDLWGGSLSYIGFTNFD 212 Query: 210 FGSDLADKSHNN-----KRTSNAIASSHILSLLYEHWKFAFTLRYFHNGGQWNAGEKVNF 264 +GSDL D + + RTSN+IASSHIL+L Y HW ++ RYFHNGGQW K+NF Sbjct: 213 WGSDLGDDNFYDLNGKHARTSNSIASSHILALNYAHWHYSIVARYFHNGGQWADDAKLNF 272 Query: 265 GDGPFELKNTGWGTYTTIGYQF 286 GDGPF +++TGWG Y +GY F Sbjct: 273 GDGPFSVRSTGWGGYFVVGYNF 294
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.020 Identities = 5/33 (15%), Positives = 13/33 (39%), Gaps = 1/33 (3%) Query: 17 ELVEKR-QRFATILSIIMLAVYIGFILLIAFAP 48 EL+E R +++ ++ + +L Sbjct: 47 ELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQ 79
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 29.1 bits (65), Expect = 0.013 Identities = 6/21 (28%), Positives = 10/21 (47%) Query: 179 FGNLDDPNSEISQLLHQKPTY 199 GNL++P ++ L P Sbjct: 75 TGNLEEPAVMVNYFLQGDPYQ 95
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 3e-04 Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 5/84 (5%) Query: 50 HLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAEEEARQAG 109 L L+ +G I + + N I+++ V R VG+ LL A E A++ Sbjct: 68 FLYYLENNCIGRIKIRSNW-----NGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122 Query: 110 AEMTELSTNVKRHDAHRFYLREGY 133 L T A FY + + Sbjct: 123 FCGLMLETQDINISACHFYAKHHF 146
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.014 Identities = 17/70 (24%), Positives = 25/70 (35%), Gaps = 8/70 (11%) Query: 36 CVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEI------RK 89 VVL G G GKSTL+ +L + I G + + + E+ R+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIV--AYELSEMTAFRR 655 Query: 90 TTVGWVSQFL 99 V F Sbjct: 656 ADAEAVKAFF 665
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.2 bits (172), Expect = 4e-16 Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 4/109 (3%) Query: 4 VLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIFNSDTPIDLILLDIYMQKEN 63 +L+ DDDA + + + +++ G+ S I + DL++ D+ M EN Sbjct: 6 ILVADDDAAIRTVLNQALSRA-GYDVR-ITSNAATLWRWI--AAGDGDLVVTDVVMPDEN 61 Query: 64 GLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVDYLIKPFQASR 112 DLLP + AR V+V+S+ T + G DYL KPF + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTE 110
>PF06580#Sensor histidine kinase Length = 349 Score = 41.0 bits (96), Expect = 8e-06 Identities = 21/99 (21%), Positives = 38/99 (38%), Gaps = 18/99 (18%) Query: 442 LIENALE-ALGP-EPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSE 499 L+EN ++ + GG+I + +G + EV + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------TKES 310 Query: 500 RGVGLALVKQQVENLGG---SIAVESEPGIFTQFFVQIP 535 G GL V+++++ L G I + + G V IP Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 26.4 bits (58), Expect = 0.012 Identities = 9/28 (32%), Positives = 16/28 (57%) Query: 32 LAIIEHTDVDESLKGQGIGKQLVAKVVE 59 A+IE V + + +G+G L+ K +E Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIE 116
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.0 bits (65), Expect = 0.040 Identities = 36/190 (18%), Positives = 66/190 (34%), Gaps = 14/190 (7%) Query: 44 NHAISLFSAYA-SLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL 102 H L + YA P+LG +DR G R ++ + + ++ + L Sbjct: 43 AHYGILLALYALMQFACAPVLGAL-SDRF-GRRPVLLVSLAGAAVDYAIMAT-APFLWVL 99 Query: 103 YLALAIIICGYGLFKSNISCLLGELYDEND-HRRDGGFSLLYAAGNIGSIAAPIACGLAA 161 Y+ + G+ + + + D D R F + A G +A P+ GL Sbjct: 100 YIGRIV----AGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG 155 Query: 162 QWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKF-ALPVWTWLVVMLC 220 + H F A + L FL+G + +++ L L + W M Sbjct: 156 G-FSPHAPFFAAA---ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTV 211 Query: 221 LAPVFFTLLL 230 +A + + Sbjct: 212 VAALMAVFFI 221
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 36.8 bits (85), Expect = 8e-05 Identities = 16/97 (16%), Positives = 36/97 (37%), Gaps = 7/97 (7%) Query: 391 PLDEKQLAALNTEIDNIVTLPELNNLS-----IIYQIKAVSALVKGKTDESYQAINTGID 445 ++ A+ + + T+ LN +S +Y + A + GK +++++ Sbjct: 6 TDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSL-AFNQYQSGKYEDAHKVFQALCV 64 Query: 446 LEMSWLNYVL-LGKVYEMKGMNREAADAYLTAFNLRP 481 L+ + L LG + G A +Y + Sbjct: 65 LDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDI 101
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.0 bits (106), Expect = 3e-08 Identities = 28/188 (14%), Positives = 51/188 (27%), Gaps = 13/188 (6%) Query: 3 REDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPDKEAILYDALRYLSQQIDA 62 R+ +L AL+L QG+++T+L +A+ + + DK + + I Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 63 WRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIAACTFYPDPGH----PIHQLA 118 + L + E + F+ + Q Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLEST--VTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 119 DQQKSAAYDFTHELLTT-------LEVDDPAMVAKQMELVLEGCLSRMLVNRSQADVDTA 171 +YD + L A M + G + L D+ Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKE 190 Query: 172 HRLAEDIL 179 R IL Sbjct: 191 ARDYVAIL 198
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 50.8 bits (121), Expect = 2e-08 Identities = 50/312 (16%), Positives = 105/312 (33%), Gaps = 18/312 (5%) Query: 121 SRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLGTLTGNSPLNQAQNFALQSDS 180 + ++ QERA + N L + +D ++ LT L+ + Sbjct: 49 TDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTE---ELSNAKEKLRKND 105 Query: 181 ARLKALVDEL-ELAQLSANNRQELARLRSELAEKES--QQLDAYLQALRNQLNSQRQLEA 237 L ++ EL A+ + L + + + L+A AL + + + Sbjct: 106 KSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAAR-KADLEKAL 164 Query: 238 ERALESTELLAENSADLPKDIVAQFKINRELSAALNQQAQRMDLVASQQRQAASQTLQVR 297 E A+ + + L + A EL AL +++ + ++ + Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224 Query: 298 QALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQQLDTEMAQLRVQRLRYEDLLNKQ 357 L + L + A A++ L + L+ A+L + Sbjct: 225 ARKADLEKA---LEGAMNFSTADSAKIKTLEA--EKAALEARQAELEKALEGAMNFSTAD 279 Query: 358 PQLRQIHQADGQPLTAE------QNRILEAQLRTQRELLNSLLQGGDTLLLELTKLKVSN 411 + +A+ L AE Q+++L A ++ R L++ + L E KL+ N Sbjct: 280 SAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQN 339 Query: 412 GQLEDALKEVNE 423 E + + + Sbjct: 340 KISEASRQSLRR 351 Score = 42.4 bits (99), Expect = 1e-05 Identities = 48/239 (20%), Positives = 92/239 (38%), Gaps = 23/239 (9%) Query: 20 ATAPDSKQISQELEQAKAAKPAQPEVVEALQSALNALEERKGSLER-IKQYQEVIDNYPK 78 A A + + LE A A ++ L++ ALE R+ LE+ ++ Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 79 LSATLRAQLNNMRDEPRSVSPGMSTDALNQEILQVSSQLLDKSRQAQQEQERAREIADSL 138 TL A+ + E + + Q + LD SR+A+++ E + + Sbjct: 282 KIKTLEAEKAALEAEKADL---EHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQ 338 Query: 139 NQLPQQQTDARRQLNEIERRLGTLTGNSPLNQAQNFALQSDSARLKAL--VDELELAQLS 196 N++ ++A RQ + R L L+++ +L+ + E L Sbjct: 339 NKI----SEASRQ--SLRRDLDASR-------EAKKQLEAEHQKLEEQNKISEASRQSLR 385 Query: 197 AN---NRQELARLRSELAEKESQQLDAYLQALRNQLNSQRQLEAERALESTELLAENSA 252 + +R+ ++ L E S +L A + + S++ E E+A +L AE A Sbjct: 386 RDLDASREAKKQVEKALEEANS-KLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKA 443
>SECA#SecA protein signature. Length = 901 Score = 32.2 bits (73), Expect = 0.005 Identities = 26/144 (18%), Positives = 54/144 (37%), Gaps = 6/144 (4%) Query: 282 HVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEENK-PIRV 340 ++D +DV N + IDA+ P L ++ + + R+ D + PI Sbjct: 665 ELLDVSDVSETINSIREDVFKATIDAYIPPQSL--EEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 341 WLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV 400 WL + L + + + + + + R + LQ ++ W E ++ Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782 Query: 401 SLQVRMPIVDWRRLCKQEPALIDY 424 +R I R +++P +Y Sbjct: 783 D-YLRQGIH-LRGYAQKDP-KQEY 803
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 0.006 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 10/81 (12%) Query: 17 GSSKPGGNSEGNGNKGGRDQGPPDLDDIFRKLSKKLGGLGGGKGTGSGGGSSSQGP---- 72 S G +SE N GG G G GGG GTG G S+ P Sbjct: 33 ASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG-GNLSAVAAPVAFG 91 Query: 73 -----RPQLGGRVVTIAAAAI 88 P GG V+I+A A+ Sbjct: 92 FPALSTPGAGGLAVSISAGAL 112
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.029 Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 165 VVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAV-GKIVEVLGDNM 218 +VP+D L L+ I +G ++++ P R + GK+ + D + Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.8 bits (62), Expect = 0.034 Identities = 6/19 (31%), Positives = 7/19 (36%), Gaps = 2/19 (10%) Query: 105 FNGDVQI--ELTGYWTWEQ 121 F G + L W EQ Sbjct: 62 FKGQEDLGNGLKAIWQVEQ 80
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 42.2 bits (99), Expect = 1e-06 Identities = 51/246 (20%), Positives = 78/246 (31%), Gaps = 55/246 (22%) Query: 18 MNKVIAVSALAMAGMFSTQALADESKTGFYVTGKAGASVMSLADQRFLSGDGEETSKYKG 77 M K A+A+AG F+T A A +Y K G S D F++ Sbjct: 1 MKKTAIAIAVALAG-FATVAQAAPKDNTWYTGAKLGWS--QYHDTGFIN---------NN 48 Query: 78 GDGHDTVFSGGIAAGYDFYPQFSIPVRTELEFYARGKADSKYNVDKDSWSGGYWRDDLKN 137 G H+ G GY P E+ + G+ K +V+ + Sbjct: 49 GPTHENQLGAGAFGGYQVNPYVGF----EMGYDWLGRMPYKGSVE-----------NGAY 93 Query: 138 EVSVNTLMLNAYYDFRNDSAFTPWVSAGIGYARIHQKTTGISTWDYGYGSSGRESLSRSG 197 + L Y +D + G R K YG + +S Sbjct: 94 KAQGVQLTAKLGYPITDD--LDIYTRLGGMVWRADTK-------SNVYGKNHDTGVS--- 141 Query: 198 SADNFAWSLGAGVRYDVTPDIALDLSYRYLDAGDSSVSYKDEWGDKYKSEVDVKSHDILL 257 GV Y +TP+IA L Y++ + GD + + + L Sbjct: 142 ------PVFAGGVEYAITPEIATRLEYQWT----------NNIGDAHTIGTRPDNGMLSL 185 Query: 258 GVTYNF 263 GV+Y F Sbjct: 186 GVSYRF 191
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 27.9 bits (62), Expect = 0.010 Identities = 13/67 (19%), Positives = 27/67 (40%), Gaps = 4/67 (5%) Query: 4 ISAIESMD----IIADINSIKELIDDVKYARKLTRVAKSSPVILANIENEKIIEFCKIYP 59 I I ++ ++ D S EL + Y+ + + + S + L + I++ K Sbjct: 88 IVDIHQINQDRIVVIDFESTDELGFNSIYSLIIEIMGRHSNMTLIRKRDNIIMDSIKHIT 147 Query: 60 VLVNRIR 66 +N R Sbjct: 148 PDINTYR 154
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.011 Identities = 19/171 (11%), Positives = 53/171 (30%), Gaps = 18/171 (10%) Query: 267 QGELEGIRRNESFLKDVLANWLAFLDPAKQLESIQAQQQLLDDGFREAMRDLAAFVGDAQ 326 Q I N+ + +++ L+ + F + Sbjct: 154 QILSRSIELNKLPELKLPDEPYFQNVSEEEV---LRLTSLIKEQFSTWQNQKYQKELNLD 210 Query: 327 VEQTQLEDNMDSLQTHIGQAMSLREQLGKRRALLEYDLV-QHRFNKQKAIVDALQDEADT 385 ++ + + + + + + +L +LL + +H +Q+ +E Sbjct: 211 KKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRV 270 Query: 386 NQRQIEITHAAI------------DYKAYAKALNEYRQADEDLKVFQSETE 424 + Q+E + I +K + L++ RQ +++ + E Sbjct: 271 YKSQLEQIESEILSAKEEYQLVTQLFK--NEILDKLRQTTDNIGLLTLELA 319
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 28.5 bits (63), Expect = 0.016 Identities = 10/35 (28%), Positives = 18/35 (51%) Query: 49 AGIAATLMTGTQFTPADFTGGIKSKCVKLLIEQGF 83 +GI + G+Q TP TG ++ + L + G+ Sbjct: 116 SGIGNAVTLGSQVTPGKITGTAPARKITLYAKLGY 150
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 58.0 bits (140), Expect = 4e-12 Identities = 36/136 (26%), Positives = 53/136 (38%), Gaps = 28/136 (20%) Query: 95 SPDVLFGLGSTELKPKFKLILDDFFPRYLKVLDNYQEHITEVRIEGHTSTDWTGTTNPDI 154 DVLF LKP+ + LD + L N V + G+ TD G+ Sbjct: 218 KSDVLFNFNKATLKPEGQAALD----QLYSQLSNLDPKDGSVVVLGY--TDRIGSD---- 267 Query: 155 AYFNNMALSQGRTRAVLQYVYDIKNIATHQQWVKSKFAAVGYSSAHPILDKTGKEDPNRS 214 AY N LS+ R ++V+ Y+ K I K +A G ++P+ T R+ Sbjct: 268 AY--NQGLSERRAQSVVDYLI-SKGIP------ADKISARGMGESNPVTGNTCDNVKQRA 318 Query: 215 ---------RRVTFKV 221 RRV +V Sbjct: 319 ALIDCLAPDRRVEIEV 334
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 32.1 bits (72), Expect = 0.005 Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 19/111 (17%) Query: 242 EWQENYKTQVELMSEQYQQSVESLVETKTAVAGIWEECKEIPLAMSELREVLQVNQHQIS 301 EWQ++ + L + Q QQS E + ++ E+ +++ + NQ QI Sbjct: 239 EWQQSLSQHISLFTRQGQQSAELRLHP--------QDLGEVQISLK-----VDDNQAQIQ 285 Query: 302 ELSRHLETFVAIRDKATTVLPEIQNKMAEVGELLKSGAANVSASLEQTSQQ 352 +S H +R LP ++ ++AE G ++ G +N+S QQ Sbjct: 286 MVSPHQH----VRAALEAALPVLRTQLAESG--IQLGQSNISGESFSGQQQ 330
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.030 Identities = 26/163 (15%), Positives = 59/163 (36%), Gaps = 16/163 (9%) Query: 334 RLASGAEEEAYRRLVESQFRDDDDEQAQSN---KGRLFKITLEKALFSSPMACASVVANR 390 + S E L++ QF +++ Q + + A + + V +R Sbjct: 177 QNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSR 236 Query: 391 LKRLESRKDHN--SQSQINELESLLLALNNIDASQFSKYQLLLDTIRKDLAWKANNTEDR 448 L S ++ + E E+ + N S+ L+ I ++ + ++ Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQ----LEQIESEIL----SAKEE 288 Query: 449 LVIFTESIKTLEFLEQ--QLRADLKLKDDQIATLRGDQGDTVL 489 + T+ K E L++ Q ++ L ++A Q +V+ Sbjct: 289 YQLVTQLFKN-EILDKLRQTTDNIGLLTLELAKNEERQQASVI 330
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 1053 bits (2725), Expect = 0.0 Identities = 852/855 (99%), Positives = 855/855 (100%) Query: 2 AGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIY 61 AGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIY Sbjct: 24 AGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIY 83 Query: 62 LNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIH 121 LNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIH Sbjct: 84 LNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIH 143 Query: 122 DATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGN 181 DATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGN Sbjct: 144 DATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGN 203 Query: 182 SHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTL 241 SHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTL Sbjct: 204 SHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTL 263 Query: 242 GDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNS 301 GDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNS Sbjct: 264 GDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNS 323 Query: 302 TVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEY 361 TVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEY Sbjct: 324 TVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEY 383 Query: 362 RSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQ 421 RSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQ Sbjct: 384 RSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQ 443 Query: 422 ANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIE 481 ANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIE Sbjct: 444 ANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIE 503 Query: 482 TQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRSSTLYLSGSHQTYWGTNNVDEQFQ 541 TQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR+STLYLSGSHQTYWGT+NVDEQFQ Sbjct: 504 TQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQ 563 Query: 542 AGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSM 601 AGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSM Sbjct: 564 AGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSM 623 Query: 602 SHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIG 661 SHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIG Sbjct: 624 SHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIG 683 Query: 662 YSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRG 721 YSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRG Sbjct: 684 YSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRG 743 Query: 722 YAVLPYATEYRENRVALDTNTLADNVDLDNSVANVVPTRGAIVRAEFKARVGIKLLMTLT 781 YAVLPYATEYRENRVALDTNTLADNVDLDN+VANVVPTRGAIVRAEFKARVGIKLLMTLT Sbjct: 744 YAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLT 803 Query: 782 HNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPP 841 HNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPP Sbjct: 804 HNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPP 863 Query: 842 ESQQQLLTQLSAECR 856 ESQQQLLTQLSAECR Sbjct: 864 ESQQQLLTQLSAECR 878
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 31.5 bits (71), Expect = 0.001 Identities = 31/158 (19%), Positives = 49/158 (31%), Gaps = 9/158 (5%) Query: 3 WRKRGYLLAAMLAFASATIQAADVTITVNGKVVAKPCTVSTTNATIDLGDLYSFSLVSAG 62 W R + A LA + +TI + VT VN + + I + G Sbjct: 258 WMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDHNAAQAGIIASNKTH------IG 311 Query: 63 AASAWHDVALELTHCPVG--TSRVTASFSGAADSTGYYKNQGTAQNIQLELQDDSGNTLN 120 W L + P G + S + Q ++QN + N+ Sbjct: 312 TLDLWQSAGLNIIAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPPNSAQ 371 Query: 121 TGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQA 158 + QV D + V +N A GTI+ Sbjct: 372 KTEIQPTQVIDGPFAGGKNTVVNINRINTNA-DGTIRV 408
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 28.1 bits (62), Expect = 0.047 Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 1/79 (1%) Query: 211 SQNLGYYLSGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVS 270 S+N G ++ +A+ N FT PA V V L ++G ++ + + + Sbjct: 133 SENAGKEITIGSAN-PNVTFTEKTGDQPASTVKVTLDQDGVAKLSSVQIKNVYAIDTTYN 191 Query: 271 LGLTANYARTGGQVTAGNV 289 + TG VT G V Sbjct: 192 SNVNFYDVTTGATVTTGAV 210
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.008 Identities = 10/49 (20%), Positives = 25/49 (51%) Query: 230 LVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVAFV 278 + +I ++ I +W V +T W ++ FI + P+A + + ++ + Sbjct: 73 MGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSII 121
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 575 bits (1485), Expect = 0.0 Identities = 197/537 (36%), Positives = 298/537 (55%), Gaps = 13/537 (2%) Query: 266 AISGLSVQNGIAIGPVKWFTCERPEITQRTVDSPQEELSRIESAIDIVVCEL------AD 319 I+G++ +G+AI +I + ++ E+ ++ +A++ EL + Sbjct: 4 KITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTE 63 Query: 320 KAAGPE-GDIFAAHKMMLEDPKINRQLQQRLAK-GKQAEFAWLEVMQALAEQYCQAETLY 377 + G + +IFAAH ++L+DP++ ++ ++ AE+A EV + + Y Sbjct: 64 ASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEY 123 Query: 378 LREREADIRDLTRQVLNQLCGGSEQHFITTA-PCILLANDLLPSQITSLNKAHILGICLH 436 ++ER ADIRD++++VL L G T A +++A DL PS LNK + G Sbjct: 124 MKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATD 183 Query: 437 NGGTTSHTAILARAMGIPAIVKAAITPQNVRDNDTVILDGETGRLWLQPDEVTRLDLLQR 496 GG TSH+AI++R++ IPA+V + ++ D VI+DG G + + P E ++ Sbjct: 184 IGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEK 243 Query: 497 AEAWRQQRDRQLADAMQPAVTQGGRKISVLANIGDLQDIEAALSHGAEGVGLLRTEFLFH 556 A+ +Q+ +P+ T+ G + + ANIG +D++ L++G EG+GL RTEFL+ Sbjct: 244 RAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLYM 303 Query: 557 ESATLPDEEEQFRVYCSVAQAFGDKPVTIRTLDIGGDKPLPSYPLPAEDNPFLGLRGIRL 616 + LP EEEQF Y V Q KPV IRTLDIGGDK L LP E NPFLG R IRL Sbjct: 304 DRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAIRL 363 Query: 617 CLAHPQIFIPQLRALLRAGKEYPTLQIMLPMVSTLEEVNAVKTLIQTQAKLL---GLTAE 673 CL IF QLRALLRA Y L++M PM++TLEE+ K ++Q + L G+ Sbjct: 364 CLEKQDIFRTQLRALLRAS-TYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVS 422 Query: 674 NLPALGIMIEVPAAVMIAEKLASEVDFFSIGTNDLTQYIMAADRGNSTVAELVDYRNDAV 733 + +GIM+E+P+ + A A EVDFFSIGTNDL QY MAADR N V+ L + A+ Sbjct: 423 DSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAI 482 Query: 734 INAIAMVCQAGRNNEIPVSMCGEMAGDTQQTARLLTMGIDKLSASPSRLPALKAAIR 790 + + MV +A + V MCGEMAGD LL +G+D+ S S + + ++ + Sbjct: 483 LRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLL 539
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.0 bits (83), Expect = 2e-04 Identities = 58/324 (17%), Positives = 106/324 (32%), Gaps = 25/324 (7%) Query: 39 TGATNAELGFLMTAYGLVNFLLYLPGGWAADRFSARKLMTFSLISTGISGFYYATFPSYT 98 + A G L+ Y L+ F G +DRF R ++ SL + AT P Sbjct: 38 SNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW 97 Query: 99 MICLLHALWAVTTVFTFWAVCVRIIRTLGTSEEQGRLYGYWFLGKGLTSIVLGFLSVPVF 158 ++ + + +T T AV I + +E+ R +G+ + G ++ PV Sbjct: 98 VLYIGRIVAGITGA-TG-AVAGAYIADITDGDERARHFGF--MS---ACFGFGMVAGPVL 150 Query: 159 AKFGEGVDGLRATIIFYSVVTILAGVLAWFVCQDETHSEDKANFRLADMAF-----VLKM 213 G A + + L + F+ + E + R A M Sbjct: 151 GGLMGGF-SPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGM 209 Query: 214 PTVWLAGVVTFCMWSI-YIGFGMVTPYLTQILHMGESEVAVASILRAYVLFAMGGLIGGQ 272 V V F M + + + + H + + ++ + L Sbjct: 210 TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGIS----LAAFGILHSLAQAM 265 Query: 273 LADRCASRTRFMIYAFIGMIVFTTVYFFLP--GESRYVTIALANMVALGVFIYSANAVFF 330 + A+R +GMI T Y L + + + G+ + + A+ Sbjct: 266 ITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLS 325 Query: 331 SIIDEIRIPAKVTGTAAGLISLLT 354 +DE R G G ++ LT Sbjct: 326 RQVDEER-----QGQLQGSLAALT 344
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 228 bits (582), Expect = 1e-69 Identities = 82/355 (23%), Positives = 157/355 (44%), Gaps = 41/355 (11%) Query: 327 RKIAQQQISTNANFTFDSLHAASGGMKQVLLIARRAIKSISPILINGEEGVGKLSLAMAI 386 K ++ ++ L S M+++ + R +++ ++I GE G GK +A A+ Sbjct: 122 PKRRPSKLEDDSQ-DGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 387 HNESEQRDGPFISVDCQMLSPENILHELLGSDVG-------PSPSKFELAHNGTLYLDKV 439 H+ ++R+GPF++++ + + I EL G + G S +FE A GTL+LD++ Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 440 EYLSGEVQSVLLKVLKTGLVTRSDSHRLIPVRFRLITCTSSSLREYVQQGAFSRQLYYEI 499 + + Q+ LL+VL+ G T I R++ T+ L++ + QG F LYY + Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 500 SMNEIEIPPLRKRREDLKQMIDDIIDKYQERTRKKMTITPDANSVLLEYRWPGNISEFKN 559 ++ + +PPLR R ED+ ++ + + ++ +A ++ + WPGN+ E +N Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELEN 360 Query: 560 RMEKVFINCNRLVLGLENIPLDIRQN-----NSSGDDDIPHLT----------------- 597 + ++ + V+ E I ++R L+ Sbjct: 361 LVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFG 420 Query: 598 -----------SLAELEMQAIEHTCRVCEWNLTKAAEVLKIGRTTLWRKLKIYNL 641 LAE+E I N KAA++L + R TL +K++ + Sbjct: 421 DALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 33.6 bits (77), Expect = 0.001 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 20/85 (23%) Query: 26 CDVLVANGKIIAVASNIPSDIVPDCT--------VVDLSGQILCPGFIDQHVHLIGGGGE 77 D+ + +G+I A+ D+ P T V+ G+I+ G +D H+H I Sbjct: 86 ADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFI----- 140 Query: 78 AGPTTRTPEVALSRLTEAGVTSVVG 102 + E AL +G+T ++G Sbjct: 141 ---CPQQIEEALM----SGLTCMLG 158
>INTIMIN#Intimin signature. Length = 939 Score = 577 bits (1487), Expect = 0.0 Identities = 178/592 (30%), Positives = 275/592 (46%), Gaps = 33/592 (5%) Query: 136 NGENTLENQIASTSQRVGPLLSQDMNSEQASGMARGWASSEASGAMTDWLNNFGTAKISL 195 N Q AS ++ S+ +N + A A G A ++AS + WL ++GTA+++L Sbjct: 161 KALNYAAQQAASLGSQLQ---SRSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNL 217 Query: 196 GVDEDFSLKNSQFDFLHPWYDTPDYLLFSQHTLHRTDDRTQINTGLGWRHFTPSWMSGIN 255 +F S DFL P+YD+ L F Q D R N G G R F P M G N Sbjct: 218 QSGNNFD--GSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYN 275 Query: 256 LFFDHDLSRYHSRAGLGAEYWRDYLKLSSNAYIGLTGWRSAPELDNDYEARPANGWDLRA 315 +F D D S ++R G+G EYWRDY K S N Y ++GW + DY+ RPANG+D+R Sbjct: 276 VFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYN-KKDYDERPANGFDIRF 334 Query: 316 EGWLPAWPQLGGKLVYEQYYGDEVALFDKNDRQSNPHAITAGLNYTPFPLLTLSAEQRQG 375 G+LP++P LG KL+YEQYYGD VALF+ + QSNP A T G+NYTP PL+T+ + R G Sbjct: 335 NGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHG 394 Query: 376 KQGENDTRFAVDLTWQPSSSMQKQLNPDEVAGRRSLAGSRYDLIDRNNNIVLEYRKKELI 435 END +++ +Q +Q+ P V R+L+GSRYDL+ RNNNI+LEY+K++++ Sbjct: 395 TGNENDLLYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDIL 454 Query: 436 HLSLQDPVKGKSGEIKPLVSSIQTKYALKGYNIEAAALEAAGGKVRTSG----KDITVTL 491 L++ + G + + +++KY L + +AL + GG+++ SG +D L Sbjct: 455 SLNIPHDINGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAIL 514 Query: 492 PGYRFTNTPETDNTWSIDVTAEDVKGNLSRHEQ-SMVVIQAPTLSQKDSLLSVNPLTVAA 550 P Y N + + A D GN S + ++ V+ + + + +A Sbjct: 515 PAY----VQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSA 570 Query: 551 DKKSTTTLTVTAHDSD------GTPVPGLALQTRSEGVQDITLSDWTDNGDGSYTQMLTA 604 T +T TA PV + G ++ + NG G T L + Sbjct: 571 KADGTEAITYTATVKKNGVAQANVPVSFNIVS----GTAVLSANSANTNGSGKATVTLKS 626 Query: 605 GTTSGSVTLTPQINGESAVKESIVVNIVPVVSSRDHSSITIDNVSYYAGDDIKVRVELKD 664 V SA+ + V I + + I D + A + +K Sbjct: 627 DKPGQVVVSAKTAEMTSALNANAV--IFVDQTKASITEIKADKTTAVANGQDAITYTVKV 684 Query: 665 DSN-QPVAYQKEELVKAVTVENSKPGATIVWHEEQPGVYAANYPAHKQGTAL 715 +PV+ Q+ + K + + G + G +L Sbjct: 685 MKGDKPVSNQEVTFTTTL----GKLSNSTE-KTDTNGYAKVTLTSTTPGKSL 731 Score = 73.2 bits (179), Expect = 7e-15 Identities = 83/435 (19%), Positives = 145/435 (33%), Gaps = 43/435 (9%) Query: 961 NTVILTASVKDVYGHPLPDEDVKFTLPASMTGNFTLSSETARTDANGDAVVTLRGTKAGE 1020 ++ + + + + +D + LPA + G + TAR G + Sbjct: 489 DSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDR-------NGNSSNN 541 Query: 1021 FTVTATLTRNNTVAHQQ--VTFIGDTNSAQLQPLTASLNTIVAGDSTGSTLTATILDAYQ 1078 +T T+ N V Q F D SA+ A + T TAT+ Sbjct: 542 VLLTITVLSNGQVVDQVGVTDFTADKTSAK------------ADGTEAITYTATVKKNGV 589 Query: 1079 NPLKDQLV-TFQSNDVTLSGTEVTTNTLGQATVTMTSNIAGQHNVVVSRKAQVSDNKTFS 1137 + S LS TN G+ATVT+ S+ GQ VV ++ A+++ + Sbjct: 590 AQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQ-VVVSAKTAEMTSALNAN 648 Query: 1138 LSVLPDESSAKVISITGAEKTITVGENITLRILVQDAFN-NVISGQRVRLSAQPTANITI 1196 + D++ A + I + T + V+ +S Q V + ++ Sbjct: 649 AVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFT-TTLGKLSN 707 Query: 1197 GDTAYTDNNGYAYVNLISTQPGVYQVTATLDNNSSSKVDVNVAN-GKLELTSSKPETTVH 1255 T TD NGYA V L ST PG V+A + + + V L + E Sbjct: 708 -STEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGT 766 Query: 1256 NSEGITLTATARNARDEL-MPGQIITFSVTPEGATLSNTGEILTDQSGQAKVTLTSNKVN 1314 +G T + + L G ++ +N I + + +VTL + Sbjct: 767 GVKGKLPTVWLQYGQVNLKASGGNGKYTW-----RSANPA-IASVDASSGQVTL--KEKG 818 Query: 1315 VYTVTATMGKDVPVQSQVTVAVKADAKTAHVVSVVASPDTITADGVDSSTITSRVEDDYG 1374 T++ T + +V + S D V++ Sbjct: 819 TTTISVISS------DNQTATYTIATPNSLIVPNM-SKRVTYNDAVNTCKNFGGKLPSSQ 871 Query: 1375 FPVEGVDVSYALDTK 1389 +E V ++ K Sbjct: 872 NELENVFKAWGAANK 886 Score = 66.2 bits (161), Expect = 8e-13 Identities = 65/278 (23%), Positives = 105/278 (37%), Gaps = 21/278 (7%) Query: 1168 RILVQDAFNNVISGQRVRLSAQPTANITIGDTAYTDNNGYAYVNLISTQPGVYQVTATLD 1227 RI+ D+ GQ +Q + AY N+ Y Sbjct: 484 RIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQ----GGSNVYKVTARAYDRNGNSS 539 Query: 1228 NNSSSKVDVNVANGKL-------ELTSSKPETTVHNSEGITLTATARNARDELMPGQIIT 1280 NN + V ++NG++ + T+ K +E IT TAT + ++ Sbjct: 540 NNVLLTITV-LSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKK-NGVAQANVPVS 597 Query: 1281 FSVTPEGATLSNTGEILTDQSGQAKVTLTSNKVNVYTVTA-TMGKDVPVQSQVTVAVKAD 1339 F++ A LS T+ SG+A VTL S+K V+A T + + + V D Sbjct: 598 FNIVSGTAVLSANSA-NTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFV--D 654 Query: 1340 AKTAHVVSVVASPDTITADGVDSSTITSRVEDDYGFPVEGVDVSYALDTKGSPVVNIPTT 1399 A + + A T A+G D+ T T +V PV +V T + + T Sbjct: 655 QTKASITEIKADKTTAVANGQDAITYTVKV-MKGDKPVSNQEV--TFTTTLGKL-SNSTE 710 Query: 1400 RTDQSGQVTATITSTLAETLIVNVQVPGTANQSATITL 1437 +TD +G T+TST +V+ +V A + Sbjct: 711 KTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEV 748 Score = 63.5 bits (154), Expect = 6e-12 Identities = 66/344 (19%), Positives = 111/344 (32%), Gaps = 26/344 (7%) Query: 848 LVADPDTIIAGNSQGSTLTATVTDFHNNPLKDMKVNFVAPGGSQLDNTTATTDQSGIVRV 907 AD + A ++ T TATV + G + L +A T+ SG V Sbjct: 563 FTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATV 622 Query: 908 HLTSSKAGSYSVDASLEADKNIHQSVTITVVPNREQSVMTLNAGSGSAIANNTNTVILTA 967 L S K G V A + + + V + S+ + A +A+AN + + T Sbjct: 623 TLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTV 682 Query: 968 SVKDVYGHPLPDEDVKFTLPASMTGNFTLSSETARTDANGDAVVTLRGTKAGEFTVTATL 1027 V P+ +++V FT N T +TD NG A VTL T G+ V+A + Sbjct: 683 KVMK-GDKPVSNQEVTFTTTLGKLSN-----STEKTDTNGYAKVTLTSTTPGKSLVSARV 736 Query: 1028 TRNNT-VAHQQVTFIGDTNSAQLQPLTASLNTIVAGDSTGSTLTATI-LDAYQNPLKDQL 1085 + V +V F + IV G T + Sbjct: 737 SDVAVDVKAPEVEFFTTLT------IDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGN 790 Query: 1086 VTFQSNDVTLSGTEVTTNTLGQATVTMTSNIAGQHNVVVSRKAQVSDNKTFSLSVLPDES 1145 + + + + VT+ G + V SDN+T + ++ Sbjct: 791 GKY---TWRSANPAIASVDASSGQVTL--KEKGTTTISVI----SSDNQTATYTI--ATP 839 Query: 1146 SAKVISITGAEKTITVGENI-TLRILVQDAFNNVISGQRVRLSA 1188 ++ ++ T N + N + A Sbjct: 840 NSLIVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGA 883 Score = 33.9 bits (77), Expect = 0.007 Identities = 34/283 (12%), Positives = 80/283 (28%), Gaps = 27/283 (9%) Query: 502 TDNTWSIDVTAEDVKGNLSRHEQSMVVIQAPTLSQKDSLLSVNPLTVAADKKSTTTLTVT 561 + V + S + V+ + + + T A+ + T TV Sbjct: 625 KSDKPGQVVVSAKTAEMTSALNANAVIF-VDQTKASITEIKADKTTAVANGQDAITYTVK 683 Query: 562 AHDSDGTPVPGLALQTRSEGVQDITLSDWTDNGDGSYTQMLTAGTTSGSVTLTPQINGES 621 PV T + + ++ S + +G LT TT G ++ +++ + Sbjct: 684 V-MKGDKPVSN-QEVTFTTTLGKLSNSTEKTDTNGYAKVTLT-STTPGKSLVSARVSDVA 740 Query: 622 AVKESIVVNIVPVVSSRDHSSITIDNVSYYAGDDIKVRVELKD-DSNQPVAYQKEELVKA 680 ++ V ++ DD + + P + + V Sbjct: 741 VDVKAPEVEFFTTLTI----------------DDGNIEIVGTGVKGKLPTVWLQYGQVNL 784 Query: 681 VTVENSKPGATIVWHEEQPGVYAANYPAHKQGTALRAQLSLHNWNAPLQSHIYNIEANQN 740 + W P + + + + + + ++ ++ Q+ Y I + Sbjct: 785 KASGGN---GKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNS 841 Query: 741 KARVATLSATNNDVYADKKTFNTLTINVTDESDNPLTNHQVTF 783 + + + Y D S N L N + Sbjct: 842 ---LIVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAW 881
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.0 bits (65), Expect = 0.037 Identities = 64/316 (20%), Positives = 113/316 (35%), Gaps = 24/316 (7%) Query: 82 RPFLLASALATGLLILAMAWLPPFLLVFIIRFLAGV-----ASAGMLIFGSTLIMQHTRH 136 RP LL S + MA P +++I R +AG+ A AG I T + RH Sbjct: 73 RPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARH 132 Query: 137 PFVLAALFSGVGVGIALGNEYVLAGLHFALSSQTLWQGAGALSAIILLALALLIP-SNKH 195 ++A F G G+ G VL GL S + A AL+ + L L+P S+K Sbjct: 133 FGFMSACF---GFGMVAGP--VLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKG 187 Query: 196 VIPPAPLAKIAQQPMSWW---------LLAILYGLAGFGYIIVATYLPLMAKDAGQPVLT 246 P + W L+A+ + + G + A ++ + +D T Sbjct: 188 ERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWV-IFGEDRFHWDAT 246 Query: 247 AHLWTLVGLSIVPGCFGWLWA---AKRWGALPCLTANLLVQAICVLLTLASSSPLLLIIS 303 +L I+ + A R G L ++ +L ++ + Sbjct: 247 TIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPI 306 Query: 304 SIGFGGTFMGTTSLVMTIARQLSVPGNLNLLGFVTLIYGIGQILGPALTSMLGNGTSALA 363 + +G +L ++RQ+ L G + + + I+GP L + + + Sbjct: 307 MVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTW 366 Query: 364 SATLCGAAALFIAALI 379 + A A + Sbjct: 367 NGWAWIAGAALYLLCL 382
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 49.9 bits (119), Expect = 1e-08 Identities = 46/189 (24%), Positives = 76/189 (40%), Gaps = 5/189 (2%) Query: 7 RHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFNADVSLAPAAVSLYLAGGMALQW 66 RH L + L + + ++ P I N A + A L + G A+ Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAV-- 68 Query: 67 LLGPLSDRIGRRPVLINGALIFTLACAATMFTTSMTQFLI-ARAIQGTSICFIATVGYVT 125 G LSD++G + +L+ G +I S LI AR IQG + V Sbjct: 69 -YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 126 VQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAALMHFMHWKVLFAIIAVMGFISFVGLL 185 V + K +I SIV + +GP G + H++HW L +I ++ I+ L+ Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL-LIPMITIITVPFLM 186 Query: 186 LAMPETVKR 194 + + V+ Sbjct: 187 KLLKKEVRI 195
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 29.7 bits (66), Expect = 0.022 Identities = 13/70 (18%), Positives = 23/70 (32%), Gaps = 4/70 (5%) Query: 149 KQQHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFP 208 K+ ++ I ++Y + + + I T D + + I A Sbjct: 135 KEAQMMNEIAEFYAAPFKKTRAINEKEAFECI-YDSRTRSA--GKD-IVSVKINIDKAKK 190 Query: 209 AQNFPPADYI 218 N P DYI Sbjct: 191 ILNLPECDYI 200
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.9 bits (236), Expect = 1e-24 Identities = 33/149 (22%), Positives = 62/149 (41%), Gaps = 9/149 (6%) Query: 4 RILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQ 63 ILV +D+A IR ++ L + G+ + + + DL++ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 FIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRI 123 + +K+ D+PV++++A+ ++ E GA DY+ KPF EL+ I + Sbjct: 65 LLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA-- 120 Query: 124 SPMAVEEVIEMQGLSLDPTSHRVMAGEEP 152 E L D + G Sbjct: 121 -----EPKRRPSKLEDDSQDGMPLVGRSA 144
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 0.001 Identities = 19/105 (18%), Positives = 33/105 (31%), Gaps = 26/105 (24%) Query: 325 LVYNAVNH----TPEGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKAR 380 LV N + H P+G I ++ + VE+ G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 381 SRQTGGSGLGLAIVKHAVNH---HESRLNIESTVGKGTRFSFVIP 422 +G GL V+ + E+++ + GK +IP Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>PF06580#Sensor histidine kinase Length = 349 Score = 32.5 bits (74), Expect = 0.004 Identities = 29/184 (15%), Positives = 67/184 (36%), Gaps = 34/184 (18%) Query: 306 EELTRMAKMVSDML-FLAQADNNQLIPEKKMLNLADEVGKVFDFFEALAEDR-GVELRFV 363 + M +S+++ + + N + + LADE+ V + + LA + L+F Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVS------LADELTVVDSYLQ-LASIQFEDRLQFE 243 Query: 364 GDECQVAGDPLMLRRALSNLLSNALRY----TPTGETIVVRCQTVDHLVQVTVENPGTPI 419 D + + L+ N +++ P G I+++ + V + VEN G+ Sbjct: 244 NQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA 303 Query: 420 APEHLPRLFDRFYRIDPSRQRKGEGSGIGLAIVK---SIVVAHKGTVAVTSDARGTRFVI 476 E +G GL V+ ++ + + ++ ++ Sbjct: 304 LKN------------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 477 ILPA 480 ++P Sbjct: 346 LIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.7 bits (212), Expect = 2e-21 Identities = 35/117 (29%), Positives = 62/117 (52%) Query: 2 KLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWD 61 +L+ +D+ L + L+ AG+ V + N + GD DL++ D+++PD N +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 IVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRR 118 ++ ++ A +P+L+++A T +K E GA DYL KPF EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.5 bits (87), Expect = 8e-05 Identities = 26/189 (13%), Positives = 60/189 (31%), Gaps = 13/189 (6%) Query: 254 QAQTVNSDSLQSVKLPA-GLPSQILLQRPDIMEAEHALM-----AANANIGAARAAFFPS 307 + +S + +K + +I+++ + + L+ A A+ ++ Sbjct: 87 NGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQS----- 141 Query: 308 ISLTSGISTASSDLSSLFNASSGMWNFIPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYE 367 SL + + + + P F + L + + ++Q Sbjct: 142 -SLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN 200 Query: 368 QKIQNAFKEVADALALRQSLNDQISAQQRYLASLKITLQRARALYQHGAVSYLEVLDAER 427 QK Q + A R ++ +I+ + K L +L A++ VL+ E Sbjct: 201 QKYQ-KELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQEN 259 Query: 428 SLFATRQTL 436 L Sbjct: 260 KYVEAVNEL 268
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 696 bits (1798), Expect = 0.0 Identities = 213/1059 (20%), Positives = 440/1059 (41%), Gaps = 54/1059 (5%) Query: 1 MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQI 60 M + IRR + A+ L + G I+ PV P ++ V + +YPG Q Sbjct: 1 MANFFIRR----PIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQT 56 Query: 61 VENQVTYPLTTTMLSVPGAKTVRGFSQ-FGDSYVYVIFEDGTDPYWARSRVLEYLNQVQG 119 V++ VT + M + + S G + + F+ GTDP A+ +V L Sbjct: 57 VQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATP 116 Query: 120 KLPAGVSAELGP-DATGVGWIYEYALVDRSGKHDLADLRSLQDWFLKYELKTIPDVAEVA 178 LP V + + + ++ V + D+ +K L + V +V Sbjct: 117 LLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQ 176 Query: 179 SVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELA------EAEYMVR 232 G ++ +D L +Y ++ +V + L N + + + + Sbjct: 177 LFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 233 ASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQVGPEMRRGIAELNGEGEVAGGVVILR 292 A + ++F + L+ + +G V L+DVA+V++G E IA +NG+ AG + L Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLA 294 Query: 293 SGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAIDNLSGKLLEEFIVVAVV 352 +G NA + A+K KL L+ P+G++++ YD + + +I + L E ++V +V Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 353 CALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIE 412 LFL ++R+ L+ I++P+ L F ++ G + N +++ G+ +A+G +VD AIV++E Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 413 NAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPALFISLLIITLSFIPIFTLEGQEG 472 N + + E D + + ++ AL ++++ FIP+ G G Sbjct: 415 NVERVMME----------DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 473 RLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGKIPPESSNPLNRF----------LI 522 ++ + T AMA + L+A+++ P L ++ + E F + Sbjct: 465 AIYRQFSITIVSAMALSVLVALILTPALCATLLKP-VSAEHHENKGGFFGWFNTTFDHSV 523 Query: 523 RVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQINEGDLLYMPSTLPGISA 582 Y + K+L LL+ AL V ++ ++ FLP+ ++G L M G + Sbjct: 524 NHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQ 583 Query: 583 AEAASMLQKTDKLIM--SVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQDQW-RPG 639 +L + + V VF G + + + LKP ++ Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQN---AGMAFVSLKPWEERNGDE 640 Query: 640 MTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADI-DTMAE 698 + + +I + + + +++ + I +G + + Sbjct: 641 NSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQ 700 Query: 699 QIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTVADVQLFVTSAVGGAMVGE 758 + A+ + S LE +E+++EKA G++++D+ +++A+GG V + Sbjct: 701 LLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVND 760 Query: 759 TVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITLADVADVKVSTGPSMLKTENA 818 ++ + ++ +R P+ + +L + + + + + G L+ N Sbjct: 761 FIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNG 820 Query: 819 RPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPM 878 P+ I +A L + +A K L G ++G + ++ +V + Sbjct: 821 LPSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAI 878 Query: 879 TLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGVAA 938 + +++F+ L + + ++ VP +VG + V G + G++A Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 939 EFGVVMLMYLRHAIEAEPSLNNPQTFSEQKLDEALYHGAVLRVRPKAMTVAVIIAGLLPI 998 + ++++ + + +E E + + EA +R+RP MT I G+LP+ Sbjct: 939 KNAILIVEFAKDLMEKE----------GKGVVEATLMAVRMRLRPILMTSLAFILGVLPL 988 Query: 999 LWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKL 1037 GAGS + + ++GGM++A LL++F +P + + Sbjct: 989 AISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVV 1027
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 43.2 bits (102), Expect = 8e-07 Identities = 41/201 (20%), Positives = 64/201 (31%), Gaps = 34/201 (16%) Query: 19 AFLFLFAPTAFAAEQTVEAPSVDARAW----------ILMDYASGKVLAEGNADEKLDPA 68 + L A A P + I MD ASG+ L ADE+ Sbjct: 7 CIISLLATLPLAV-HASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMM 65 Query: 69 SLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLN 128 S K++ V + A +L + + +P V D ++V +L Sbjct: 66 STFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSP------VSEKHLADGMTVGELC 119 Query: 129 KGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKKLGLTNTT---FQTVHGLDAPGQF- 184 I S N A L V G + + +++G T ++T PG Sbjct: 120 AAAITMSDNSAANLLLATVGGPAG-----LTAFLRQIGDNVTRLDRWETELNEALPGDAR 174 Query: 185 --STARDMA------LLGKAL 197 +T MA L + L Sbjct: 175 DTTTPASMAATLRKLLTSQRL 195
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.0 bits (96), Expect = 6e-06 Identities = 59/269 (21%), Positives = 106/269 (39%), Gaps = 23/269 (8%) Query: 71 LLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAI 130 +LG LSDR GRRPV+L + V + A + + R + GI+ GAV A I Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYI 120 Query: 131 QESFEEAVCIKITALMANVALIAPLLGPLVG---AAWIHVLPWEGMFVLFAALAAISFFG 187 + + + M+ + GP++G + P F AAL ++F Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP----FFAAAALNGLNFLT 176 Query: 188 LQRAMPETATRIGEKLSLKELGRDYKLVLKNG-RFVAGALALGFVSLPLLAWIAQSP--I 244 +PE+ L + L G VA +A+ F ++ + Q P + Sbjct: 177 GCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF----IMQLVGQVPAAL 232 Query: 245 IIITGEQLSSYEYGLLQVPIFGALIAGNL----LLARLTSRRTVRSLIIMGGWPIMIGLL 300 +I GE ++ + + + I +L + + +R R +++G G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 301 VAAAATVISSHAYLWMTAGLSLYAFGIGL 329 + A AT ++ + L + GIG+ Sbjct: 293 LLAFAT----RGWMAFPIMVLLASGGIGM 317
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.9 bits (80), Expect = 5e-04 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 6/150 (4%) Query: 218 LLIGVVVLAMAFAEGSANDWL-PLLMVDGHGFSP-TSGSLIYAGFTLGMTVGRFTGGWFI 275 +IGV+ + F + + P +M D H S GS+I T+ + + + GG + Sbjct: 258 FMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILV 317 Query: 276 DRYSRVAVVR-ASALM--GALGIGMIIFVDSAWVA-GVSVVLWGLGASLGFPLTISAASD 331 DR + V+ + L ++ S ++ + VL GL + TI ++S Sbjct: 318 DRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSL 377 Query: 332 TGPDAPTRVSVVATTGYLAFLVGPPLLGYL 361 +A +S++ T +L+ G ++G L Sbjct: 378 KQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 51.6 bits (123), Expect = 1e-10 Identities = 14/81 (17%), Positives = 31/81 (38%) Query: 2 RRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGSMTYYFSGIDELLLEAFS 61 + + R+ I+ L G+ + + +IA AGV G++ ++F +L E + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 62 RFTEIMSRQYQAFFSDVSDAP 82 + + + P Sbjct: 65 LSESNIGELELEYQAKFPGDP 85
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.1 bits (73), Expect = 0.006 Identities = 21/106 (19%), Positives = 34/106 (32%), Gaps = 6/106 (5%) Query: 394 LMIGMITFQFSTFSFGMGNAAGLLFAGIML-GFMRANHPTFG-YIPQ--GALSMVKEFGL 449 L++ + +L+ G ++ G A G YI + FG Sbjct: 76 LLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGF 135 Query: 450 MVFMAGVGLSAGSGINNGLGAIGGQM--LIAGLIVSLVPVVICFLF 493 M G G+ AG + +G A + L + CFL Sbjct: 136 MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLL 181
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 55.6 bits (134), Expect = 1e-10 Identities = 29/125 (23%), Positives = 52/125 (41%), Gaps = 17/125 (13%) Query: 4 RILVLGASGYIGQHLVRTLSQQGHQILA---------AARHVDRLAKLQLANVSCHKVDL 54 + LV GA+G+IG H+ + L + GHQ++ + RL L HK+DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 55 SWPDNLPALLQD--IDTVYFLVH------SMGEGGDFIAQERQVALNVRDALREVPVKQL 106 + + + L + V+ H S+ + LN+ + R ++ L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 107 IFLSS 111 ++ SS Sbjct: 122 LYASS 126
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 920 bits (2379), Expect = 0.0 Identities = 300/1036 (28%), Positives = 513/1036 (49%), Gaps = 29/1036 (2%) Query: 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAV 72 + FI RP+ +L + +++AG + LPV+ P + P + V YPGA + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 73 TAPLERQFGQMSGLKQMSSQS-SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 T +E+ + L MSS S S G+ ITL FQ D+A+ +VQ + AT LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVE--DMVETRVAQKISQISGVGLVTLSGG 189 + + S + +M S TQ + D V + V +S+++GVG V L G Sbjct: 122 VQQQGI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 190 QRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGP------SRAVTLSANDQ 243 Q A+R+ L+A + LT V + N A G L G ++ A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 244 MQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANI 302 ++ EE+ ++ + +G+ +RL DVA VE G EN + A N + A + ++ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 303 ISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFL 362 + TA +I+ L +L P+ +KV D T ++ S+ + L AI LV +++YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 363 RNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRY 422 +N+ AT+IP +AVP+ L+GTFA++ +SIN LT+ + +A G +VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 423 I-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAIL 481 + E P A K +I ++ + L AV IP+ F G G ++R+F+IT+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISAVVSLTLTPMMCARML---SQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWL 538 +S +V+L LTP +CA +L S E + F FD + Y + K+L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 539 TLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQ 598 L + + V+L++ +P F P +D G+ +Q P ++ + QV D L+ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 599 DPA--VQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDR---VQKVIARLQTAVDKVPG 653 + V+S+ + G + + N+ ++LKP +ER+ + VI R + + K+ Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR- 658 Query: 654 VDLFLQPTQDLTIDTQVSRTQYQFTLQ---ATSLDALSTWVPQLMEKLQQLP-QLSDVSS 709 D F+ P I + T + F L DAL+ QL+ Q P L V Sbjct: 659 -DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 710 DWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTE 769 + + + VD++ A LG+S++D++ + A G ++ + ++ ++ + + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 770 NTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLG 829 +D + + S++G +VP S+ + + + P I S G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 830 DAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFI 889 DA A+M+ + LP I + G + + + L+ + V +++ L LYES+ Sbjct: 838 DA-MALMENLAS-KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 890 HPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQ 949 P++++ +P VG LLA + + DV ++G++ IG+ KNAI++++FA ++ Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 950 GMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQV 1009 G EA A +R RPILMT+LA +LG LPL +S G G+ + +GIG++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1010 LTLFTTPVIYLLFDRL 1025 L +F PV +++ R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.4 bits (97), Expect = 6e-06 Identities = 32/167 (19%), Positives = 66/167 (39%), Gaps = 11/167 (6%) Query: 126 ALAQALGQLAKDKATLANARRDLARYQQLVKTNLVSRQELDAQQALVSETEGTIKADEAS 185 +A+ +L K+ L ++ ++ +L + L + T + Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILSAKE----EYQLVTQLFKNEILDKLRQTTDNIGLLT 315 Query: 186 --VASAQLQLDWSRITAPVDGRV-GLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPE 242 +A + + S I APV +V LK G +++ +T +V++ + +++ + Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTALVQN 374 Query: 243 SDIATVVQAQKAGKPLVVEAWDRTNSKKL-SEGTLLSLDNQIDATTG 288 DI + Q A + VEA+ T L + ++LD D G Sbjct: 375 KDIGFINVGQNA--IIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLG 419 Score = 41.4 bits (97), Expect = 6e-06 Identities = 23/144 (15%), Positives = 52/144 (36%), Gaps = 18/144 (12%) Query: 59 LAPVQAATA-VEQAVPRYLTGLGTITAA-NTVTVRSRVDGQLMALHFQEGQQVKAGDLLA 116 +A + + VE G +T + + ++ + + + +EG+ V+ GD+L Sbjct: 70 IAFILSVLGQVEIVAT----ANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLL 125 Query: 117 EIDPSQFKVALAQALGQLAKDKATLANARRDLARYQQLVKTNLVSRQELDAQQALVSETE 176 ++ + + +++L AR + RYQ L ++ EL+ L E Sbjct: 126 KLTALGAEADTLKT-------QSSLLQARLEQTRYQILSRS-----IELNKLPELKLPDE 173 Query: 177 GTIKADEASVASAQLQLDWSRITA 200 + L + + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFST 197
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 50.1 bits (120), Expect = 8e-09 Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 20/129 (15%) Query: 132 AMMLH-IRQQAQAQLPEAITQAVIGRPINFQGLGGDEANAQAQGILERAAKRAGFKDVVF 190 M+ H I+Q + ++ P+ + E A + +A+ AG ++V Sbjct: 89 KMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQV---ERRA-----IRESAQGAGAREVFL 140 Query: 191 QYEPVAAGLDYEATLQEEKRVLVVDIGGGTTDCSLLLMGPQWRSRLDREASLLGHSGCRI 250 EP+AA + + E +VVDIGGGTT+ +++ + ++ S RI Sbjct: 141 IEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN-----------GVVYSSSVRI 189 Query: 251 GGNDLDIAL 259 GG+ D A+ Sbjct: 190 GGDRFDEAI 198 Score = 35.9 bits (83), Expect = 2e-04 Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 23/137 (16%) Query: 332 RLSYRLV---RSAEESKIALSSV--AETRASLPFISDELAT------LISQQGLENALSQ 380 R +Y + +AE K + S + + LA ++ + AL + Sbjct: 203 RRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQE 262 Query: 381 PLARILEQVQLALDNAQEKPDV--------IYLTGGSARSPLIKKALAEQLPGIPIAGGD 432 PL I+ V +AL+ Q P++ + LTGG A + + L E+ GIP+ + Sbjct: 263 PLTGIVSAVMVALE--QCPPELASDISERGMVLTGGGALLRNLDRLLMEET-GIPVVVAE 319 Query: 433 D-FGSVTAGLARWAEVV 448 D V G + E++ Sbjct: 320 DPLTCVARGGGKALEMI 336
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.2 bits (73), Expect = 4e-04 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Query: 80 APNYLRRGVASLILRHILQVAHDRCLHRLSLETGTQAGFTACHQLYLKHGFVDC 133 A +Y ++GV + +L ++ A + L LET +ACH Y KH F+ Sbjct: 98 AKDYRKKGVGTALLHKAIEWAKENHFCGLMLET-QDINISACH-FYAKHHFIIG 149
>PF01206#SirA family protein Length = 76 Score = 92.5 bits (230), Expect = 6e-29 Identities = 16/71 (22%), Positives = 37/71 (52%) Query: 7 DYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQ 66 D LD G CP P + + + + GE+L V++ P S+ + ++ G+ +L+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 67 DGPTIRYLIQK 77 + T + +++ Sbjct: 65 EDGTYHFRLKR 75
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.017 Identities = 10/57 (17%), Positives = 17/57 (29%), Gaps = 2/57 (3%) Query: 164 RFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRF--RLGMLVFFGMLGWALLTAMNQ 218 R L R + + + A L + P R R M ++L + Sbjct: 26 RKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEI 82
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 32.7 bits (74), Expect = 0.003 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 2/95 (2%) Query: 214 NGMEVSVAAQNAQLTVNNVAIENSSNTISDALENITLNLNDVTTGNQTLTITQDTSKAQT 273 N E +VAA+N + + A+ + +S AL T++L V+T LT T T ++ Sbjct: 236 NSSERAVAARNKAEELVSAALYSRPELLSQALSGKTVDLKIVSTS--LLTPTSLTGGEES 293 Query: 274 AIKDWVNAYNSLIDTFSSLTKYTAVDAGADSQSSS 308 +KD VNA L TK ++ + S Sbjct: 294 MLKDQVNALKGLNSKRGEPTKLLIRNSDGLLKEVS 328
>FLAGELLIN#Flagellin signature. Length = 507 Score = 209 bits (533), Expect = 3e-63 Identities = 238/543 (43%), Positives = 294/543 (54%), Gaps = 36/543 (6%) Query: 2 AQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 61 AQVINTNSLSL+TQNN+NK+QS+LSS+IERLSSGLRINSAKDDAAGQAIANRFTSNIKGL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 TQAARNANDGISVAQTTEGALSEINNNLQRIRELTVQASTGTNSDSDLDSIQDEIKSRLD 121 TQA+RNANDGIS+AQTTEGAL+EINNNLQR+REL+VQA+ GTNSDSDL SIQDEI+ RL+ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EIDRVSGQTQFNGVNVLAKDGSMKIQVGANDGQTITIDLKKIDSDTLGLSGFNVNGSADK 181 EIDRVS QTQFNGV VL++D MKIQVGANDG+TITIDL+KID +LGL GFNVNG + Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEA 180 Query: 182 ASVAATADGMVKDGYIKGLTSSDGSTAYTKTTANTAAKGSDILAALKTGDKITATGANSL 241 + S T Y D+ + D T + + Sbjct: 181 TVGDLKS-------------SFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKV 227 Query: 242 ADNATSTTYTYNATSNTFSYTADGVNQTNAAANLIPAAGKTTAASVTIGGTAQNVNIDDS 301 NA + T + N + ++ A A Sbjct: 228 YVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTI 287 Query: 302 GNITSSDGDQLYLDSTGNLTKNQAGNPNKATVSGLLGNTDAKGTAVKTTIKTEAGVTVTA 361 T +DG+ + + + + T V A Sbjct: 288 DTKTGNDGNG-----------------------KVSTTINGEKVTLTVADITAGAANVDA 324 Query: 362 EGNTGTVKIEGATVSASAFTGIAYSANTGGNTYAVAANNTTNGFLAGDALTQDAQTVSTY 421 + + + V+ + + A N + + Sbjct: 325 ATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGD 384 Query: 422 YSQADGTVTNSAGKEIYKDADGVYSTENKTSKTSDPLAALDDAISSIDKFRSSLGAIQNR 481 G T++PLA++D A+S +D RSSLGAIQNR Sbjct: 385 KVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNR 444 Query: 482 LDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLS 541 DSA+TNL NT TNL+ A+SRI+DADYATEVSNMSKAQI+QQAG SVLA+ANQVPQ VLS Sbjct: 445 FDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLS 504 Query: 542 LLQ 544 LL+ Sbjct: 505 LLR 507
>PF05844#YopD protein Length = 295 Score = 33.1 bits (75), Expect = 0.001 Identities = 12/28 (42%), Positives = 22/28 (78%), Gaps = 2/28 (7%) Query: 76 MDLLALLYRLMAKSRQMGMFSLERDIEN 103 ++LL +L+R+ K+R++G+ L+RD EN Sbjct: 74 VELLLILFRIAQKARELGV--LQRDNEN 99
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.010 Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 11/93 (11%) Query: 46 LISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPNIEE 105 L +SSP A P + G + ++ PGGGDD GE +++ Sbjct: 384 LADVSSPTAAAGGAGGGEPPKKRDPSAG---AGTDPGGPGGGDD-----GEDPFGEWLDD 435 Query: 106 LKKRM---EQSRLRKLRGDLDQLIESDPKLRAL 135 R+ + L+ R L + + S P L Sbjct: 436 EVARLRLRGRWLLKPRRAALIEALRSAPALAGC 468
>PF06580#Sensor histidine kinase Length = 349 Score = 42.5 bits (100), Expect = 4e-06 Identities = 23/151 (15%), Positives = 49/151 (32%), Gaps = 52/151 (34%) Query: 359 ELDKSLIERIIDPLT--HLVRNSLDHGIELPEKRLAAGKNSVGNLILSAEHQGGNICIEV 416 +++ ++++ + P+ LV N + HGI G ++L G + +EV Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEV 296 Query: 417 TDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVV 476 + G+ + G G+ V Sbjct: 297 ENTGSLALKNTK--------------------------------------ESTGTGLQNV 318 Query: 477 KRNIQEMGG---HVEIQSKQGTGTTIRILLP 504 + +Q + G +++ KQG +L+P Sbjct: 319 RERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 8e-14 Identities = 35/188 (18%), Positives = 72/188 (38%), Gaps = 23/188 (12%) Query: 1 MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMP 60 M+ +L DD A +R ++ + ++ V + I + D++ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 RMDGLDFLEKLMRLRPMPVVMVSSLTGKGS-EVTLRALELGAIDFVTKPQLGIREGMLAY 119 + D L ++ + RP V+V ++ + + ++A E GA D++ KP + E + Sbjct: 59 DENAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGII 115 Query: 120 SEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLP 179 +AE R +K + + +G S E R + + + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMP-----------------LVGRSAAMQEIYRVLARLMQ 158 Query: 180 LSSPALLI 187 ++ Sbjct: 159 TDLTLMIT 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 9e-24 Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 7 KFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGLDALNKLQAGGYGFVISDWNMPNMDGL 66 LV DD + +R ++ L G++ V + + AG V++D MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPF 111 +LL I+ LPVL+++A+ I A++ GA Y+ KPF Sbjct: 64 DLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.007 Identities = 9/16 (56%), Positives = 14/16 (87%) Query: 38 LVGESGSGKSLIAKAI 53 + GESG+GK L+A+A+ Sbjct: 165 ITGESGTGKELVARAL 180
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 67.5 bits (165), Expect = 1e-14 Identities = 68/312 (21%), Positives = 114/312 (36%), Gaps = 18/312 (5%) Query: 5 SLSWALILGLLAGIGPMCTDLYLPALPEMSEQLAATTTITQLTLTASLIGLGVGQLLFGP 64 L L L +G L +P LP + L + +T L + Q P Sbjct: 6 PLIVILSTVALDAVG---IGLIMPVLPGLLRDLVHSNDVTA-HYGILLALYALMQFACAP 61 Query: 65 ----LSDKIGRKRPLILSLLLFIVSSILCATTNNIYWLVVWRFIQGIAGAGGSVLSRSIA 120 LSD+ GR+ L++SL V + AT ++ L + R + GI GA G+V IA Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA 121 Query: 121 RDKYQGVTLTQFFALLMTVNGLAPVLSPVLGGYIVSTFDWRTLFWVMAEISTVLLLGCLL 180 D G + F + G V PVLGG + F F+ A ++ + L Sbjct: 122 -DITDGDERARHFGFMSACFGFGMVAGPVLGGLM-GGFSPHAPFFAAAALNGLNFLTGCF 179 Query: 181 FINETLPENKRGSSL----LLTGRSVVQNRRFMRFCLIQSFMLAGLFAYIGSSSFVL--Q 234 + E+ +R L + + + F + L + ++ +V+ + Sbjct: 180 LLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF-IMQLVGQVPAALWVIFGE 238 Query: 235 KEFGFSPMQFSLVFGLNGI-GLIIASWIFSRLARRINAMTLLRGGLIAAILCALLTVLCA 293 F + + GI + + I +A R+ L G+IA +L Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 294 WTQLPIPALVAL 305 + P +V L Sbjct: 299 RGWMAFPIMVLL 310
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.048 Identities = 24/166 (14%), Positives = 49/166 (29%), Gaps = 11/166 (6%) Query: 70 DVQKAIADIDSARALYGQTNASLFPTVNAALSSTRSRSLANGTGTTAEADGTVSSYTLDL 129 A AD ++ Q +RS L + + + + Sbjct: 128 TALGAEADTLKTQSSLLQARL----EQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEE 183 Query: 130 FGRNQSLSRAARETWLASEFTAQNTRLTLIAEISTAWLTLAADNSNLALAKETMASAENS 189 R SL + TW ++ + AE T + + + ++ Sbjct: 184 VLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTV-------LARINRYENLSRVEKSR 236 Query: 190 LKIIQRQQQVGTAAATDVSEAMSVYQQARASVASYQTQVMQDKNAL 235 L A V E + Y +A + Y++Q+ Q ++ + Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEI 282
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1161 bits (3005), Expect = 0.0 Identities = 583/1033 (56%), Positives = 760/1033 (73%), Gaps = 6/1033 (0%) Query: 3 SRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLENSV 62 + FF+RRP+FAWV+AI++M+AG LAI LPVAQYP +APP + +SA Y GA A+T++++V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 63 TQVIEQQLTGLDNLLYFSSTSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLPSE 122 TQVIEQ + G+DNL+Y SSTS S GSV+I +TF+ GTDPD AQVQVQNK+Q A LP E Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 123 VQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLVSNVQDPLARVEGVGSLQVFGAE 182 VQQ G++VEKS S++L++A + DI+D++ SNV+D L+R+ GVG +Q+FGA+ Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ 181 Query: 183 YAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPNTQQLTATVRAQSRLQ 242 YAMRIWLD L Y L P DV + ++ QN Q+ AG++G P+ QQL A++ AQ+R + Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 243 TVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANALN 302 ++F + ++ SDG+VVR+KDVARVE+G E+Y I ++NG P+AG+ + L+ GANAL+ Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 303 TATLVKDKIAEFQRNMPQGYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFLQN 362 TA +K K+AE Q PQG + YP D+T F+++S+ +V++TLFEAI+LV VMYLFLQN Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 363 LRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMVLAIGLLVDDAIVVVENVERIMR 422 +RATLIP +AVPVVLLGTF +LA FGYSINTLT+F MVLAIGLLVDDAIVVVENVER+M Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 423 DEGLPAREATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAMLLS 482 ++ LP +EATEKSM +I GALV IA+VLSAVF+PMAFFGGSTG IYRQFSITI+SAM LS Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 483 VVVALTLTPALCGSVL----QHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRAARTM 538 V+VAL LTPALC ++L +K GFFG FN + + + Y V +L R + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 539 GLYVVLGGGMALMMWKLPGSFLPTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINE 598 +Y ++ GM ++ +LP SFLP EDQG + LPAGAT RT +V Q+ D++L NE Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 599 KANTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTAQAIALRATKELGTIRDAT 658 KAN + +FTV+GFSFSG QN GMAFVSLK W +R G EN+A+A+ RA ELG IRD Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 659 VFAMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSP-ELHSVRANDLP 717 V PA+ LG + GF FEL+ G + L Q RNQL+ A Q P L SVR N L Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 718 QMPQLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSA 777 Q ++++D KA +LG+SL+D+ T+S+A GGTYVNDFIDRGRVKK+Y+Q D++FR Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 778 PSDLGKWFVRGSDNAMTPFSAFATTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMT 837 P D+ K +VR ++ M PFSAF T+ W+YG RL RYNG + EIQGE A G SSGDAM Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 838 KMEELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVFLCLAALYESWSVPFSVI 897 ME LA+ LPAG + W+G+S QE+L+ QA +L A+S +VVFLCLAALYESWS+P SV+ Sbjct: 842 LMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVM 901 Query: 898 LVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFA-EAAVAEGYSLSR 956 LV+PLG++G LAA + + NDVYF V LLTTIGLS+KNAILIVEFA + EG + Sbjct: 902 LVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVE 961 Query: 957 AALRAAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFV 1016 A L A + RLRPI+MTSLAFI GV+PLAI+ GAG+ ++ A+G G++GG ++ATLLAIFFV Sbjct: 962 ATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFV 1021 Query: 1017 PLFFVLVKRLFAG 1029 P+FFV+++R F G Sbjct: 1022 PVFFVVIRRCFKG 1034 Score = 75.3 bits (185), Expect = 1e-15 Identities = 53/330 (16%), Positives = 117/330 (35%), Gaps = 19/330 (5%) Query: 721 QLQVDIDSNKAVSLGLSLNDVTDTLSSA----WGGTYVNDFIDRGRVKKVYIQGDSEFRS 776 +++ +D++ L+ DV + L G G+ I + F++ Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 777 APSDLGKWFVRGSDN-AMTPFSAFATTRWLYGPER--LVRYNGSAA-----YEIQGENAT 828 P + GK +R + + ++ A L G + R NG A G NA Sbjct: 243 -PEEFGKVTLRVNSDGSVVRLKDVARVE-LGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 829 GFSSGDAMTKMEELANSLPAG--TTWAWSGLSLQEKLASGQALSLYAVSILVVFLCLAAL 886 + K+ EL P G + + + +L+ +LV + + Sbjct: 301 DTAKA-IKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV-MYLF 358 Query: 887 YESWSVPFSVILVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEA 946 ++ + +P+ LLG + + ++ IGL +AI++VE E Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 947 AVAEGYSLSRAALRAAQTRLR-PIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGT 1005 + E + A + ++++ ++ ++ A +P+A G+ I+ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 1006 LTATLLAIFFVPLFFVLVKRLFAGKPRRQE 1035 + L+A+ P + + + + + Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENK 508
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 48.3 bits (115), Expect = 3e-08 Identities = 28/133 (21%), Positives = 55/133 (41%), Gaps = 10/133 (7%) Query: 41 PVSVVSELTGR-TSAALSAEVRPQVGGIIQKRLFKEGDLVKAGQPLYQIDAASYQAAWNE 99 V +V+ G+ T + S E++P I+++ + KEG+ V+ G L ++ A +A + Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 100 ARAALQQAQALVKADCQKAQRYARLVKENGVSQQDADDAQSTCAQDKASV--------EA 151 +++L QA+ Q R L K + D Q+ ++ + Sbjct: 139 TQSSLLQARLEQ-TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFST 197 Query: 152 KKAALETARINLD 164 + +NLD Sbjct: 198 WQNQKYQKELNLD 210 Score = 31.7 bits (72), Expect = 0.005 Identities = 15/116 (12%), Positives = 32/116 (27%), Gaps = 9/116 (7%) Query: 83 QPLYQIDAASYQAAWN--EARAALQQAQALVKADCQKAQRYARLVKENGVSQQDADDAQS 140 L A + A + K+ ++ + KE Q ++ Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEE--YQLVTQLFKN 298 Query: 141 TCAQDKASVEAKKAALET----ARINLDWTTVTAPISGRI-GISSVTPGALVTASQ 191 L + + AP+S ++ + T G +VT ++ Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE 354
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.4 bits (133), Expect = 6e-12 Identities = 17/65 (26%), Positives = 33/65 (50%) Query: 1 MTSKLEIRHKQRQDEIINAARRCFRRCGFHAASMSQIASEAQLSVGQIYRYFANKDAIIE 60 M K + ++ + I++ A R F + G + S+ +IA A ++ G IY +F +K + Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EMVRR 65 E+ Sbjct: 61 EIWEL 65
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 50.4 bits (120), Expect = 1e-09 Identities = 51/260 (19%), Positives = 98/260 (37%), Gaps = 22/260 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAEL-AFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 + GK +TG A I +A+ + +GA + A Y +KL+ V A+ Sbjct: 6 IEGKIAFITGAAQ--GIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHDI 119 DV + A+ID + A + + D V+ G L + A F + Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEAT----FSVN--- 116 Query: 120 SSYSFVAMAKACRSMLNP-GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 S+ F A + M++ +++T+ A + +KA+ + + + Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 179 PEGVRVNAISAGPIRTLAASGI--------KDFRKMLAHCEAVTPIRRTVTIEDVGNSAA 230 +R N +S G T + + + L + P+++ D+ ++ Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVL 236 Query: 231 FLCSDLSAGISGEVVHVDGG 250 FL S + I+ + VDGG Sbjct: 237 FLVSGQAGHITMHNLCVDGG 256
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 31.4 bits (71), Expect = 0.013 Identities = 21/105 (20%), Positives = 37/105 (35%), Gaps = 2/105 (1%) Query: 526 PIDVELTESCLIENDELALSVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQV 585 P+ V S I L S + FS + + ++ Q+ D + Sbjct: 425 PLVVVFVASNFINAHLLTDSFPRYFSDKS--IDFHSYYLLQDNVYQIPDLKPDLVITHSQ 482 Query: 586 FVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESKKEDAFLTK 630 + +H + V I L++Q + V+ +K A LTK Sbjct: 483 LIPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTK 527
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.0 bits (70), Expect = 0.011 Identities = 35/166 (21%), Positives = 60/166 (36%), Gaps = 22/166 (13%) Query: 258 IMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSA---GGALSDR 314 I+S + L+ + I A A L K + + FFG F S ++ Sbjct: 474 IVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 315 LGGTRVTLVNFILMAIFSGLLFLTLPTD----GQGGSFMAFFAVFLALFLTAGLGSGSTF 370 LG T L+ + L+ +LFL LP+ G F+ L +G+T Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTM----------IQLPAGATQ 583 Query: 371 QMISVIFRKLTMDRVKAEGGSDER-----AMREAATDTAAALGFIS 411 + + ++T +K E + E + A + F+S Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVS 629
>PF06580#Sensor histidine kinase Length = 349 Score = 53.3 bits (128), Expect = 1e-09 Identities = 36/172 (20%), Positives = 73/172 (42%), Gaps = 23/172 (13%) Query: 424 PESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLD 483 P +RE+L+ + + S + +LT +++ + S +F ++ + Sbjct: 190 PTKAREMLTSLSELMRYSLRYSNARQVSLADELT------VVDSYLQLASIQFEDRLQFE 243 Query: 484 YQLPPRL----VPSHQAIHLLQIAREALSNALKH-----SQASEVVVTVAQNDNQVKLTV 534 Q+ P + VP L+Q E N +KH Q ++++ +++ V L V Sbjct: 244 NQINPAIMDVQVPPM----LVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 535 QDNGCGVPENAIRSNHYGMIIMRDRAQSLRG-DCRVRRRESGGTEVVVTFIP 585 ++ G +N S G+ +R+R Q L G + +++ E G + IP Sbjct: 297 ENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-17 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Query: 7 ATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMN 66 ATIL+ DD +RT + Q +S A + SN + D DL++ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 67 GLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQA 123 + L ++++ ++V S N + A ++GA YL K + +L+ + +A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>INTIMIN#Intimin signature. Length = 939 Score = 256 bits (656), Expect = 1e-78 Identities = 119/378 (31%), Positives = 195/378 (51%), Gaps = 21/378 (5%) Query: 79 GEQAKAFALGKVRDALSQQVNQHVESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDN 138 G+ AK ALG + Q + +++WL +G A V+++ N F GS + +P D+ Sbjct: 184 GDYAKDTALGIAGN----QASSQLQAWLQHYGTAEVNLQSGNN--FDGSSLDFLLPFYDS 237 Query: 139 DRYLTWSQLGLTQQDDGLVSNVGVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWG 198 ++ L + Q+G D +N+G GQR+ ++GYN F D + R G G E W Sbjct: 238 EKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLGIGGEYWR 297 Query: 199 EYLRLSANFYQPFAAWHE--QTATQEQRMARGYDLTARMRMPFYQHLNTSVSVEQYFGDR 256 +Y + S N Y + WHE ++R A G+D+ +P Y L + EQY+GD Sbjct: 298 DYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDN 357 Query: 257 VDLFNSGTGYHNPVALSLGLNYTPVPLVTVTARHKQGESGENQNNLGLNLNYRFGVPLKK 316 V LFNS NP A ++G+NYTP+PLVT+ ++ G EN + Y+F P + Sbjct: 358 VALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQ 417 Query: 317 QLSAGEVAESQSLRGSRYDNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQI 376 Q+ V E ++L GSRYD QRNN LEY+++ L++ + + T ++L + Sbjct: 418 QIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNI-PHDINGTERSTQKIQLIV 476 Query: 377 RSRYGIRQLIWQGDTQILS-----LTPGAQANSEEGWTLIMPDWQNGEGASNHWRLSVVV 431 +S+YG+ +++W D+ + S G+Q S + + I+P + +G SN ++++ Sbjct: 477 KSKYGLDRIVWD-DSALRSQGGQIQHSGSQ--SAQDYQAILPAYV--QGGSNVYKVTARA 531 Query: 432 EDNQGQRVSSNEITLTLV 449 D G SSN + LT+ Sbjct: 532 YDRNGN--SSNNVLLTIT 547
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 529 bits (1365), Expect = 0.0 Identities = 251/383 (65%), Positives = 294/383 (76%), Gaps = 19/383 (4%) Query: 1 MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDNDSKDGDKTYMRLG 60 MK KVL+L++PALL AGAA+AAEIYNKDGNKLDLYGKVDGLHYFSD+ SKDGD+TYMR+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQVTDQLTGYGQWEYQIQGNEPESDNS-SWTRVAFAGLKFQDVGSFDYGRNYGVVY 119 FKGETQ+ DQLTGYGQWEY +Q N E + + SWTR+AFAGLKF D GSFDYGRNYGV+Y Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 120 DVTSWTDVLPEFGGDTY-DSDNFMQQRGNGFATYRNTDFFGLVDGLDFAVQYQGKNGSAH 178 DV WTD+LPEFGGD+Y +DN+M R NG ATYRNTDFFGLVDGL+FA+QYQGKN S Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 179 GEGMT-----TNGRDDVFEQNGDGVGGSITYNY-EGFGIGAAVSSSKRTWDQNNT-GLIG 231 + + N DD+ NGDG G S TY+ GF GAA ++S RT +Q N G I Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGTIA 240 Query: 232 TGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSL------GWANKAQNFEAVAQYQF 285 GD+A+ +T GLKYDANNIYLA Y++T N T G G ANK QNFE AQYQF Sbjct: 241 GGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQF 300 Query: 286 DFGLRPSLAYLQSKGKNLGR---GYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLD-D 341 DFGLRP++++L SKGK+L DD+D++KY DVGATYYFNKN STYVDYKINLLD D Sbjct: 301 DFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLLDDD 360 Query: 342 NQFTRAAGINTDDIVALGLVYQF 364 + F + AGI+TDDIVALG+VYQF Sbjct: 361 DPFYKDAGISTDDIVALGMVYQF 383
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 47.9 bits (114), Expect = 9e-09 Identities = 26/145 (17%), Positives = 60/145 (41%), Gaps = 20/145 (13%) Query: 1 MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP 60 M +++ADD + + ++L + + + ++ L + D +++TD+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGA------PT 114 + L+ IK+ P L ++V++ N +A+ ++GA P Sbjct: 59 D---ENAFDLLPRIKKARPDLPVLVMSAQNTFM--TAIKA-------SEKGAYDYLPKPF 106 Query: 115 DLPKALAALQKGKKFTPESVSRLLE 139 DL + + + + S+L + Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLED 131
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.2 bits (203), Expect = 3e-18 Identities = 29/106 (27%), Positives = 48/106 (45%) Query: 827 ILVVDDHPINRRLLADQLGSLGYQCKTANDGVDALNVLSKNHIDIVLSDVNMPNMDGYRL 886 ILV DD R +L L GY + ++ ++ D+V++DV MP+ + + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 887 TQRIRQLGLTLPVIGVTANALAEEKQRCLESGMDSCLSKPVTLDVI 932 RI++ LPV+ ++A + E G L KP L + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 560 bits (1444), Expect = 0.0 Identities = 180/484 (37%), Positives = 268/484 (55%), Gaps = 35/484 (7%) Query: 1 MTAINRILIVDDEDNVRRMLSTAFALQGFETHCANNGRTALHLFADIHPDVVLMDIRMPE 60 MT IL+ DD+ +R +L+ A + G++ +N T A D+V+ D+ MP+ Sbjct: 1 MTGA-TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 61 MDGIKALKEMRSHETRTPVILMTAYAEVETAVEALRCGAFDYVIKPFDLDELNLIVQRTL 120 + L ++ PV++M+A TA++A GA+DY+ KPFDL EL I+ R L Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 121 QLQSMKKEIRHLHQALSTSWQWGH-ILTNSPAMMDICKDTAKIALSQASVLISGESGTGK 179 + L Q G ++ S AM +I + A++ + +++I+GESGTGK Sbjct: 120 AEP------KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGK 173 Query: 180 ELIARAIHYNSRRAKGPFIKVNCAALPESLLESELFGHEKGAFTGAQTLRQGLFERANEG 239 EL+ARA+H +R GPF+ +N AA+P L+ESELFGHEKGAFTGAQT G FE+A G Sbjct: 174 ELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGG 233 Query: 240 TLLLDEIGEMPLVLQAKLLRILQEREFERIGGHQTIKVDIRIIAATNRDLQAMVKEGTFR 299 TL LDEIG+MP+ Q +LLR+LQ+ E+ +GG I+ D+RI+AATN+DL+ + +G FR Sbjct: 234 TLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFR 293 Query: 300 EDLFYRLNVIHLILPPLRDRREDISLLANHFLQKFSSENQRDIIDIDPMAMSLLTAWSWP 359 EDL+YRLNV+ L LPPLRDR EDI L HF+Q+ E + D A+ L+ A WP Sbjct: 294 EDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLD-VKRFDQEALELMKAHPWP 352 Query: 360 GNIRELSNVIERAVVMNSGPIIFSEDLPPQIRQPV---------CNAGEAKTAPVGERN- 409 GN+REL N++ R + +I E + ++R + +G + E N Sbjct: 353 GNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENM 412 Query: 410 ----------------LKEEIKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYKLQE 453 + +E +I+ L GN+ + A +LG++R L K++E Sbjct: 413 RQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472 Query: 454 YGID 457 G+ Sbjct: 473 LGVS 476
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 28.8 bits (64), Expect = 0.008 Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 18/167 (10%) Query: 15 LLCSSTAPAVDNLHFTGNLLGKSCTPVINGSLLAEVQFPTIAASDLMHLGQSDRVPLVFQ 74 +L S A DNL F G L+ +CT V N AEV + I +L+ G + + F Sbjct: 16 VLMSQHVHAADNLTFKGKLIIPACT-VQN----AEVNWGDIEIQNLVQSGGNQK---DFT 67 Query: 75 LKDCKSSTLFSVRVTLAGTEDSELPGFLAIDASSSASGVGIGIETAAGAAVPINDTTGVT 134 + +L +++VT+ T + + + + +S+ASG G+ I I + + Sbjct: 68 VDMNCPYSLGTMKVTI--TSNGQTGNSILVPNTSTASGDGLLIYLYNSNNSGIGNAVTLG 125 Query: 135 FPLNQG-------SNTLNFNAWLQTKSG-RDVTPGDFSATATATFEY 173 + G + + A L K + + G FSATAT Y Sbjct: 126 SQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAGTFSATATLVASY 172
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 32.8 bits (74), Expect = 2e-04 Identities = 34/161 (21%), Positives = 67/161 (41%), Gaps = 18/161 (11%) Query: 1 MLWGFCSMALSNVTFHGYLVQPPNCTISDGETIELTFQDVNIDDINGSNYEQIVPYRITC 60 +L +A + G + PP CTI++G+ I + F ++N + ++ S E I+C Sbjct: 11 LLTSVAVLADVQINIRGNVYIPP-CTINNGQNIVVDFGNINPEHVDNSRGEVTKNISISC 69 Query: 61 DTPVRDPLLEMTLSWSGTQSDFDDAAVSTDIAGLGIRLKQ-------------AGQSFKL 107 P + L + ++ T + ++T+I GI L Q +G +++ Sbjct: 70 --PYKSGSLWIKVT-GNTMGVGQNNVLATNITHFGIALYQGKGMSTPLTLGNGSGNGYRV 126 Query: 108 NTPLVVDETALPALTAVPVKKSGVDLPEANFEAWATLQVDY 148 L + T+VP + L +F A++ + Y Sbjct: 127 TAGLDTARSTF-TFTSVPFRNGSGILNGGDFRTTASMSMIY 166
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 28.8 bits (64), Expect = 0.008 Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 22/142 (15%) Query: 37 PPCTVTGAEVEFGNVVI-TRIGGVNYKRPIDYKLVCNNLAMDDLRLQMQAATVVINGETV 95 P CTV AEV +G++ I + ++ + C L T+ NG+T Sbjct: 37 PACTVQNAEVNWGDIEIQNLVQSGGNQKDFTVDMNC------PYSLGTMKVTITSNGQTG 90 Query: 96 ISTGIP--------GFGIRIQKASDSSILD-LTSGA-WLPFNFSSGAPA----LEA-VPV 140 S +P G I + +++S I + +T G+ P + APA L A + Sbjct: 91 NSILVPNTSTASGDGLLIYLYNSNNSGIGNAVTLGSQVTPGKITGTAPARKITLYAKLGY 150 Query: 141 KQSGTSLTAAEFSASATIVVDY 162 K + SL A FSA+AT+V Y Sbjct: 151 KGNMQSLQAGTFSATATLVASY 172
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 747 bits (1930), Expect = 0.0 Identities = 226/881 (25%), Positives = 383/881 (43%), Gaps = 70/881 (7%) Query: 8 RLRGIACYIALAISGGSVNAWADDSIQFDPRFLELKGDTKIDLGKFSKKGYVDAGKYNLR 67 RL G + +A + + + + F+PRFL DL +F + G Y + Sbjct: 22 RLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVD 81 Query: 68 VFINKQPLSDEYDINWYVSENDPTKTYACLTPELVAALGLKEGIAKSLQWTHNDECLKPG 127 +++N + D+ + + + CLT +A++GL + +D C+ Sbjct: 82 IYLNNGYM-ATRDVTFN-TGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLT 139 Query: 128 QL-DGMEVENDLSQSALLLTVPQAYLEYTSSDWDPPSRWDDGIPGLIADYSLNAQTRHQE 186 + + D+ Q L LT+PQA++ + + PP WD GI + +Y+ + + Sbjct: 140 SMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNR 199 Query: 187 QGGEDSHDISGNGTVGANLGAWRFRADWQSDYQHTRSNDDDDDSSNSTTSKNWDWSRYYA 246 GG +SH N G N+GAWR R + Y + S+ + W + Sbjct: 200 IGG-NSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKN--------KWQHINTWL 250 Query: 247 WRALPSLKAKLSLGEDYLNSDIFDGFNYIGSSVSTDDQMLPPNLRGYAPDVSGVAHSSAK 306 R + L+++L+LG+ Y DIFDG N+ G+ +++DD MLP + RG+AP + G+A +A+ Sbjct: 251 ERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQ 310 Query: 307 VTISQMGRVLYETQVPAGPFRIQDI-GDSVSGTLHVRVEEQNGQVQEYDVTTASMPFLTR 365 VTI Q G +Y + VP GPF I DI SG L V ++E +G Q + V +S+P L R Sbjct: 311 VTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQR 370 Query: 366 QGQVRYKVMMGRPEDWNHKTEGGFFSGGEASWGVADGWSLYGGALADEHYQSAAMGVGRD 425 +G RY + G N + E F G+ GW++YGG + Y++ G+G++ Sbjct: 371 EGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKN 430 Query: 426 LAQFGALAFDVTHSHVNLDHDSAYGKGKLDGNSFRVSYAKDFDELNSRVTFAGYRFSEKN 485 + GAL+ D+T ++ L DS + DG S R Y K +E + + GYR+S Sbjct: 431 MGALGALSVDMTQANSTLPDDSQH-----DGQSVRFLYNKSLNESGTNIQLVGYRYSTSG 485 Query: 486 FMTMSEYLDANQSDMARTGND-------------------KEMYTITYNQNFAAAGVSIY 526 + ++ + + D + +T Q ++Y Sbjct: 486 YFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTS-TLY 544 Query: 527 LNYSHRTYWDRP-EQTNYNLMFSHYFNMGSIRNVSISVTGYRYEYDDNADKGMYLSMSIP 585 L+ SH+TYW + + F + ++S + + + D+ + L+++IP Sbjct: 545 LSGSHQTYWGTSNVDEQFQAGLNTAFEDIN---WTLSYSLTKNAWQKGRDQMLALNVNIP 601 Query: 586 WSD-----------SSTVTYNGSYGS-GSDSSQVGYFKRV--DDATHYQVNVGT-----S 626 +S ++ +Y+ S+ G ++ G + + D+ Y V G Sbjct: 602 FSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDG 661 Query: 627 EQHGSVDGYLSHDGSLAKVDLSANYHEGEYRSAGIALQGGATLTAHGGALHRTQSMGGTR 686 + L++ G ++ H + + + GG A+G L Q + T Sbjct: 662 NSGSTGYATLNYRGGYGNANIGY-SHSDDIKQLYYGVSGGVLAHANGVTLG--QPLNDTV 718 Query: 687 LLIDADGIANVPVESNGAPVYTNMFGKAVVADINNYYRNQAYIDLNNLPEDAEATQSVVQ 746 +L+ A G + VE N V T+ G AV+ Y N+ +D N L ++ + +V Sbjct: 719 VLVKAPGAKDAKVE-NQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVAN 777 Query: 747 ATLTEGAIGYRKFKVISGQKAMAVLRLRDGSYPPFGAEVKNDEQQQVGIVDDEGNVYLAG 806 T GAI +FK G K + L + PFGA V ++ Q GIV D G VYL+G Sbjct: 778 VVPTRGAIVRAEFKARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVYLSG 836 Query: 807 VNAGEHMTVFW--EGSAQCEI--VLPKPLPADLFSGLLLPC 843 + + V W E +A C LP L + L C Sbjct: 837 MPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 43.3 bits (102), Expect = 1e-06 Identities = 32/165 (19%), Positives = 69/165 (41%), Gaps = 2/165 (1%) Query: 34 LDTIARNFSLSASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLIT 93 L IA +F+ +S ++ TA L ++ G L D +RL++ ++ G +I Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 94 ASSQSLA-MMILGTALTGLFSVVAQILVPLA-ATLASPDKRGKVVGTIMSGLLLGILLAR 151 S ++I+ + G + LV + A + RGK G I S + +G + Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 152 TVAGLLASLGGWRTVFWVASVLMALMALALWRGLPQMKSETHLNY 196 + G++A W + + + + + + +++ + H + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.018 Identities = 23/94 (24%), Positives = 36/94 (38%), Gaps = 12/94 (12%) Query: 23 PYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALG 82 P QE+ L + + L R A+G + + T + ++L ALG Sbjct: 756 PEQELRLVETGVQGRLWALLTREGAPAAEGAAQKGYSVNTTFVTI-------ADLVQALG 808 Query: 83 -----SSRTNATRIADELEKRGWIERRESDNDRR 111 SS ++ D L + GW RE+ RR Sbjct: 809 ADPGKSSPMLEGQVRDWLNENGWEYLRETSGQRR 842
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 78.7 bits (194), Expect = 5e-18 Identities = 64/412 (15%), Positives = 120/412 (29%), Gaps = 97/412 (23%) Query: 25 LLLTLLFIIIAVAIGIYWFLVLRHFEETDDA----YVAGNQIQIMSQVSGSVTKVWADNT 80 L FI+ + I VL E A +G +I + V ++ Sbjct: 57 PRLVAYFIMGFLVIAFILS-VLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEG 115 Query: 81 DFVKEGDVLVTLDPTDARQAFEKA------------------------------------ 104 + V++GDVL+ L A K Sbjct: 116 ESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPY 175 Query: 105 ----------------KTALASSVRQTHQLMINSKQLQANIEVQKIALAKA-------QS 141 K ++ Q +Q +N + +A + + +S Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Query: 142 DYNRRVPLGNANLIGREELQHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQ 201 + L + I + + + A +L V Q ++ IL K E Q Q Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 202 AATEVRN------------------AWLALERTRIVSPMTGYVSRRAVQ-PGAQISPTTP 242 E+ + + + I +P++ V + V G ++ Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Query: 243 LMAVVPA-TNMWVDANFKETQIANMRIGQPVTITTDIYGDDVKY---TGKVVGLDMGTGS 298 LM +VP + V A + I + +GQ I + + +Y GKV + + Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF-PYTRYGYLVGKVKNI-----N 409 Query: 299 AFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYPLRIGLSTLVSVNTTNR 350 ++ G V+ + + PL G++ + T R Sbjct: 410 LDAIE--DQRLGLVFNVIISIEENCLST--GNKNIPLSSGMAVTAEIKTGMR 457
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 132 bits (333), Expect = 9e-36 Identities = 97/405 (23%), Positives = 169/405 (41%), Gaps = 23/405 (5%) Query: 17 IALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISIPLTGWLAKRV 76 I L + +F VL+ + NV++P IA + + WV T+F + +I + G L+ ++ Sbjct: 17 IWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 77 GEVKLFLWSTIAFAIASWACGVS-SSLNMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAK 135 G +L L+ I S V S ++LI R IQG A L ++ P Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN 136 Query: 136 RSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETR 195 R A L V + GP +GG I+ HW + + +P+ + + L L +E R Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVR 194 Query: 196 TERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTD 255 + D G+ L+ +GI + ML F++ I +V+V++ + Sbjct: 195 I-KGHFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIRKV 243 Query: 256 DNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGI 315 +P VD L K+ F IG LC + + G + ++P ++++V+ + G G Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 316 IPVILS-PIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGF- 373 + VI+ I G + ++ +V F ++ S + I F Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL-----LETTSWFMTIIIVFV 358 Query: 374 --AVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSI 416 ++ ++TI S L + A SL NFT L+ G +I Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 293 bits (751), Expect = e-105 Identities = 132/170 (77%), Positives = 148/170 (87%) Query: 2 PLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFA 61 PLLDSFTVDHTRM APAVRVAKTM TP GD ITVFDLRF PNK+++ E+GIHTLEHL+A Sbjct: 1 PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYA 60 Query: 62 GFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIP 121 GFMRNHLNG+ VEIIDISPMGCRTGFYMSLIGTP EQ+VADAW AAMEDVLKV++QN+IP Sbjct: 61 GFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIP 120 Query: 122 ELNVYQCGTYQMHSLQEAQDIARNILERDVRINSNEELALPKEKLQELHI 171 ELN YQCGT MHSL EA+ IA+NILE V +N N+ELALP+ L+EL I Sbjct: 121 ELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESMLRELRI 170
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 72.0 bits (176), Expect = 6e-16 Identities = 32/184 (17%), Positives = 63/184 (34%), Gaps = 38/184 (20%) Query: 90 GLGSGVIINASKGYVLTNNHVINQAQKISIQL------------NDGREFDAKLIGSDDQ 137 + SGV++ K +LTN HV++ L +G ++ + Sbjct: 102 FIASGVVVG--KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 138 SDIALLQIQN-------PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALG 190 D+A+++ + ++++ + +V G P V+ + Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP-------VATMW 212 Query: 191 RSGLNLEGLEN-FIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSN 249 S + L+ +Q D S GNSG + N E+IGI+ G+ Sbjct: 213 ESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFNGA 263 Query: 250 MART 253 + Sbjct: 264 VFIN 267
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 52.7 bits (126), Expect = 8e-10 Identities = 31/160 (19%), Positives = 59/160 (36%), Gaps = 26/160 (16%) Query: 77 RTLGSGVIMDQRGYIITNKHVINDADQIIVALQ------------DGRVFEALLVGSDSL 124 + SGV++ + ++TNKHV++ AL+ +G + Sbjct: 101 TFIASGVVVG-KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 125 TDLAVLKI-------NATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATG 177 DLA++K + + ++ + + G P + T + G Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMW--ESKG 216 Query: 178 RIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINT 217 +I + +Q D S GNSG + N E++GI+ Sbjct: 217 KI---TYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.042 Identities = 37/167 (22%), Positives = 61/167 (36%), Gaps = 27/167 (16%) Query: 3 VAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGED 62 + GAA GIG+A+A L G+ ++ D P V S A + F + Sbjct: 11 AFITGAAQGIGEAVARTL---ASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPADV 66 Query: 63 ATPA------------LEGADVVLISAGVARK------PGMDRSDLFNVNAGIVKNLVQQ 104 A + D+++ AGV R + F+VN+ V N + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 105 VAKTCPK----ACIGIITNPVNTT-VAIAAEVLKKAGVYDKNKLFGV 146 V+K + + + +NP ++AA KA K G+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL 173
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 169 bits (430), Expect = 4e-57 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 5/141 (3%) Query: 15 KALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELG 74 + ++ + +Q E+V L++ G+ N+ Q+ VSR + + V+ Y LPA+ Sbjct: 11 REIITANEIETQDELVDILKKDGY-NVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQR 69 Query: 75 VPTTSSPLKNLV---LDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTI 131 S ++L+ + ID ++V+ T PG AQ I L+D+L E I+GTI GDDTI Sbjct: 70 FNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE-IMGTICGDDTI 128 Query: 132 FTTPANGFTVKDLYEAILELF 152 K + + ILEL Sbjct: 129 LIICRTHDDTKVVQKKILELL 149
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 54.4 bits (131), Expect = 2e-10 Identities = 29/163 (17%), Positives = 59/163 (36%), Gaps = 16/163 (9%) Query: 6 RKFSRTAITVVLVILAFIAIFNAWVYYTE----SPWTRDARFSADVVAIAPDVSGLITQV 61 SR V I+ F+ I + + S I P + ++ ++ Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 62 NVHDNQLVKKGQVLFTIDQPR-------YQKALEEAQADVAYYQVLAQEKRQEAGRRNRL 114 V + + V+KG VL + Q +L +A+ + YQ+L++ E + L Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRS--IELNKLPEL 168 Query: 115 GVQAMSREEIDQANNVL---QTVLHQLAKAQATRDLAKLDLER 154 + + VL + Q + Q + +L+L++ Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211 Score = 51.4 bits (123), Expect = 2e-09 Identities = 28/147 (19%), Positives = 54/147 (36%), Gaps = 15/147 (10%) Query: 100 LAQEKRQEAGRRNRLGVQ-AMSREEIDQANNVLQT-VLHQLAKAQAT-------RDLAKL 150 E R + ++ + ++EE + + +L +L + + Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE 323 Query: 151 DLERTVIRAPADGWVTNLNVYT-GEFITRGSTAVALVKQNSFY-VLAYMEETKLEGVRPG 208 + +VIRAP V L V+T G +T T + +V ++ V A ++ + + G Sbjct: 324 RQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVG 383 Query: 209 YRAEIT----PLGSNKVLKGTVDSVAA 231 A I P L G V ++ Sbjct: 384 QNAIIKVEAFPYTRYGYLVGKVKNINL 410
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 157 bits (399), Expect = 3e-54 Identities = 98/98 (100%), Positives = 98/98 (100%) Query: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ Sbjct: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 Query: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN Sbjct: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 130 bits (329), Expect = 4e-40 Identities = 78/209 (37%), Positives = 123/209 (58%), Gaps = 3/209 (1%) Query: 1 MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVTRGAIYWHFENKTQLFN 60 MA++TK EA +TRQ +++ A+ F+Q GVS T+L +IA AA VTRGAIYWHF++K+ LF+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EMW-LQQPSLRELIQEHLTAGLEHDPFQQLREKLIVGLQYIAKIPRQQALLKILYHKCEF 119 E+W L + ++ EL E A DP LRE LI L+ R++ L++I++HKCEF Sbjct: 61 EIWELSESNIGELELE-YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 120 NDEM-LAEGVIRDKMGFNPQTLHEVLQACQQQGCIANNLDLDVVMIIIDGAFSGIVQNWL 178 EM + + R+ + + + L+ C + + +L II+ G SG+++NWL Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 179 MNMAGYDLYKQAPALVDNVLRMFMPDENI 207 +DL K+A V +L M++ + Sbjct: 180 FAPQSFDLKKEARDYVAILLEMYLLCPTL 208
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.7 bits (103), Expect = 8e-07 Identities = 39/220 (17%), Positives = 73/220 (33%), Gaps = 38/220 (17%) Query: 98 ATYQASYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADA-RQADAAV 156 K +L + E+ A + Q + I D RQ + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLV----------TQLFKNEILDKLRQTTDNI 311 Query: 157 IAAKATVESARINLAYTKVTAPISGRIGK-STVTEGALVTNGQTTELATVQQLDPIYVDV 215 + + + AP+S ++ + TEG +VT +T + V + D + V Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTA 370 Query: 216 TQSSND--FMRLKQSVEQGNLHKENATSNVELVMENGQTYP-LKGTLQ--FSDVTVDEST 270 + D F+ + Q+ +++ Y L G ++ D D+ Sbjct: 371 LVQNKDIGFINVGQNAI------------IKVEAFPYTRYGYLVGKVKNINLDAIEDQRL 418 Query: 271 GSIT--LRAV------FPNPQHTLLPGMFVRARIDEGVQS 302 G + + ++ N L GM V A I G++S Sbjct: 419 GLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRS 458 Score = 34.0 bits (78), Expect = 0.001 Identities = 22/127 (17%), Positives = 43/127 (33%), Gaps = 13/127 (10%) Query: 46 TAPLEVKTELPGR-TNAYRIAEVRPQVSGIVLSRNFTEGSDVQAGQSLYQIDPATYQASY 104 +E+ G+ T++ R E++P + IV EG V+ G L ++ +A Sbjct: 77 LGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA-- 134 Query: 105 DSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAKATVE 164 + K++++ A L RY L E ++ + Sbjct: 135 -----DTLKTQSSLLQARLEQTRYQIL-----SRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 165 SARINLA 171 +L Sbjct: 185 LRLTSLI 191
>adhesinb#Adhesin B signature. Length = 310 Score = 27.5 bits (61), Expect = 0.004 Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 10/68 (14%) Query: 1 MKR---LIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTTQDNWETAGAIAGG 57 MK+ L+ + L LA C+ + +V TN+ + T++ IAG Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKN-------IAGD 53 Query: 58 AAAVAGLT 65 + + Sbjct: 54 KINLHSIV 61
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 145 bits (367), Expect = 8e-46 Identities = 65/143 (45%), Positives = 84/143 (58%), Gaps = 2/143 (1%) Query: 3 ATLPFLILYACLSALLFFWDAKHGLLPDRFTCPLLWSGLLFYQVCNPDGLADALWGAIIG 62 TL L+L L AL F D LLPD+ T PLLW GLLF + L DA+ GA+ G Sbjct: 133 GTLAALLLTWVLVALTFI-DLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMAG 191 Query: 63 YGTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHTWTFLPRLVFLAASFACGAVVIGLL 122 Y +YW +++L KEG+GYGD K LAALGAW W LP +V L +S + IGL+ Sbjct: 192 YLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALP-IVLLLSSLVGAFMGIGLI 250 Query: 123 MRGKESLKNPLPFGPFLAAAGFV 145 + P+PFGP+LA AG++ Sbjct: 251 LLRNHHQSKPIPFGPYLAIAGWI 273
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 38.3 bits (89), Expect = 3e-06 Identities = 19/103 (18%), Positives = 43/103 (41%), Gaps = 10/103 (9%) Query: 44 EYHESIDEMKHADKYIERILFLEGIPN--LQDLGKL------GIGEDVEEMLQSDLRLEL 95 E ++ E D ER+L + G P +++ + G EM+Q+ + Sbjct: 52 ELYDHAAE--TVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYK 109 Query: 96 EGAKDLREAIAYADSVHDYVSRDMMIEILADEEGHIDWLETEL 138 + + + + I A+ D + D+ + ++ + E + L + L Sbjct: 110 QISSESKFVIGLAEENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 79.5 bits (196), Expect = 3e-18 Identities = 57/198 (28%), Positives = 87/198 (43%), Gaps = 13/198 (6%) Query: 13 VNVGTIGHVDHGKTTLTAAI------TTVLAKTYGGAARAFDQIDNAPEEKARGITINTS 66 +N+G + HVD GKTTLT ++ T L G R DN E+ RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRT----DNTLLERQRGITIQTG 59 Query: 67 HVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQV 126 + +D PGH D++ + + +DGAIL+++A DG QTR R++ Sbjct: 60 ITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKM 119 Query: 127 GVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWE 186 G+P I F+NK D + L V +++E LS + + +W+ Sbjct: 120 GIP-TIFFINKIDQNGID--LSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 187 AKILELAGFLDSYIPEPE 204 I L+ Y+ Sbjct: 177 TVIEGNDDLLEKYMSGKS 194
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 613 bits (1583), Expect = 0.0 Identities = 178/698 (25%), Positives = 304/698 (43%), Gaps = 81/698 (11%) Query: 9 RYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAAT 68 + NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWR 128 + W ++NIIDTPGH+DF EV RS+ VLDGA+++ A GVQ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKM 188 K +P I F+NK+D+ G + V IK +L A V Q V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNM 164 Query: 189 KAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEI 248 N+ +++Q ++ E +++L+EKY+ G+ L E+ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 KGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAE 308 + R N + V GSA N G+ +++ + + S Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 RHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHA 368 FKI L + R+YSGV++ D+V S K + + + Sbjct: 244 ---RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEK-EKIKITEMYTSIN 299 Query: 369 NKREEIKEVRAGDIAAAIG----LKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKT 424 + +I + +G+I L V GDT P ER+E P P++ VEP Sbjct: 300 GELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQR----ERIENPLPLLQTTVEPSK 354 Query: 425 KADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVG 484 +E + AL ++ DP R + D +++ I++ +G++ +++ ++ +++VE + Sbjct: 355 PQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIK 414 Query: 485 KPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGV 544 +P V Y E +K E + + + + + PL GS G ++ + + G Sbjct: 415 EPTVIYMERPLKK---AEYTIHIEVPPNPFWASIGLSVSPLPLGS---GMQYESSVSLGY 468 Query: 545 IPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEG 604 + + AV +GI+ + G L G+ V D I +G Y+ S+ F++ A I ++ Sbjct: 469 LNQSFQNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQV 527 Query: 605 FKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMF 664 KKA LLEP + ++ P+E D + + + + V + E+P + Sbjct: 528 LKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQ 587 Query: 665 GYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEAR 702 Y + L T GR+ E Y + V + R Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVT---TGEPVCQPR 622
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.021 Identities = 14/62 (22%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 160 ASSVEDLVTQTLEFTIEEVNADRNV-SNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI 218 A +V+D VTQ +E + ++ + S + + + L + D A QV ++L + Sbjct: 54 AQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQL 113 Query: 219 SK 220 + Sbjct: 114 AT 115
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 132 bits (334), Expect = 5e-40 Identities = 79/226 (34%), Positives = 124/226 (54%), Gaps = 9/226 (3%) Query: 28 AAKPATTADSKAAFKNDDQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAF 87 A A A + D K +Y++GA LG K + GI ++ D L G+QD Sbjct: 14 AMSTAMAATDATSLTTDKDKLSYSIGADLG-------KNFKNQGIDINPDVLAKGMQDGM 66 Query: 88 A-DKSKLSDQEIEQTLQAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSST 146 + + L++++++ L F+ + + A+ K A +N+AKG + + G+ + Sbjct: 67 SGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPS 126 Query: 147 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGL 206 GL Y++++AG G P SDTV V Y GTLIDG FD++ G+P +F++ VIPGWTE L Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEAL 186 Query: 207 KNIKKGGKIKLVIPPELAYGKAGVPG-IPPNSTLVFDVELLDVKPA 251 + + G ++ +P +LAYG V G I PN TL+F + L+ VK A Sbjct: 187 QLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKKA 232
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 30.7 bits (69), Expect = 0.021 Identities = 13/69 (18%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 261 TAIDPFKGLLLG---LFFISVGMSLNLGVLYTHL-LWVVISVVVLVAVKILVLYLLARLY 316 A+ P L + L+FIS + L +++ + W +++ V+ ++ L Sbjct: 318 AAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKA-- 375 Query: 317 GVRSSERMQ 325 S +M+ Sbjct: 376 QYTSMAKMR 384
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 31.9 bits (72), Expect = 0.001 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 16/135 (11%) Query: 11 YAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQH-- 68 Y P + D N+V P + + +HD+ ++ D F L + + Sbjct: 9 YQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCV 68 Query: 69 ----PLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESA------Y 118 P+ + P DR L F GPG N +G Y +IT PE + Sbjct: 69 QLGIPVVYTAQPGSQNP-DDRALLTDFW-GPGLN--SGPYEEKIITELAPEDDDLVLTKW 124 Query: 119 RYDALNRYPMSDVLR 133 RY A R + +++R Sbjct: 125 RYSAFKRTNLLEMMR 139
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.7 bits (74), Expect = 0.005 Identities = 28/152 (18%), Positives = 54/152 (35%), Gaps = 22/152 (14%) Query: 504 KVEPFDGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKE 563 + D + ++ E + + ++ R+ +R R + L E Sbjct: 272 AMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAE 331 Query: 564 IARLEKEME---------------------KLNAQLAQAEEKLGDSELYDQSRKAELTAC 602 +LE++ + +L A+ + EE+ SE QS + +L A Sbjct: 332 HQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS 391 Query: 603 LQQQASAKSGLEECEMAWLEAQEQLEQMLLEG 634 + + + LEE L A E+L + L E Sbjct: 392 REAKKQVEKALEEANSK-LAALEKLNKELEES 422 Score = 32.0 bits (72), Expect = 0.008 Identities = 13/125 (10%), Positives = 39/125 (31%), Gaps = 7/125 (5%) Query: 513 EDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIARLEKEME 572 + + ++ + E A A + D ++ + +++ Sbjct: 127 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST-------ADSAKIK 179 Query: 573 KLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQEQLEQMLL 632 L A+ A E + + E + TA + + ++ + ++ LE + Sbjct: 180 TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 239 Query: 633 EGQSN 637 ++ Sbjct: 240 FSTAD 244
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 31.8 bits (72), Expect = 0.002 Identities = 10/46 (21%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 71 PEANDFGLLEQTFIEYGQSGKGKSRKYLHTYDEAVPWNQVPGTFTP 116 P+ + + E ++ KG SRK++ ++ + + GTF Sbjct: 112 PDMEELDMKELSY--LSWIDKGSSRKFIIAKNDKNKFVGLQGTFQS 155
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.4 bits (76), Expect = 2e-04 Identities = 21/92 (22%), Positives = 32/92 (34%), Gaps = 16/92 (17%) Query: 55 VACIDGIVVGHLTIDVQQRPHRSHVADFGICVDSRWKNRGVASALMREMIE------MCD 108 + ++ +G + I + + D + D R K GV +AL+ + IE C Sbjct: 69 LYYLENNCIGRIKIR-SNWNGYALIEDIAVAKDYRKK--GVGTALLHKAIEWAKENHFCG 125 Query: 109 NWLRVDRIELTVFVDNAPAIKVYKKFGFEIEG 140 L I N A Y K F I Sbjct: 126 LMLETQDI-------NISACHFYAKHHFIIGA 150
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.9 bits (101), Expect = 2e-06 Identities = 48/275 (17%), Positives = 95/275 (34%), Gaps = 32/275 (11%) Query: 44 PVSQVAFSFGLLSLGLAIS----SSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSNNL 99 + V +G+L A+ + V G L +RFG + V + S + + + A + L Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL 96 Query: 100 MMLWLS---AGVLVGLADGAGYLL----TLSNCVKWFPERKGLISAFAIGSYGLGSLGFK 152 +L++ AG+ AG + + F + LG Sbjct: 97 WVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGG---- 152 Query: 153 FIDTHLLETVGLEKTFVIWGAIVLVMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMR 212 L+ F A+ + + G L+ ++ K E + R Sbjct: 153 -----LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWAR 207 Query: 213 --KPQYWMLAVMFLTACMSG----LYVIGVAKDIAQSLAHLDAISAANAVTVISIAN-LS 265 ++AV F+ + L+VI + H DA + ++ I + L+ Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVI-----FGEDRFHWDATTIGISLAAFGILHSLA 262 Query: 266 GRLVLGILSDKIARIRVITIGQVISLVGMAALLFA 300 ++ G ++ ++ R + +G + G L FA Sbjct: 263 QAMITGPVAARLGERRALMLGMIADGTGYILLAFA 297 Score = 35.6 bits (82), Expect = 3e-04 Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%) Query: 269 VLGILSDKIARIRVITIGQVISLVGMAALLFAPLNAVTFFAAIACVAFNFGGTITVFPSL 328 VLG LSD+ R V+ + + V A + AP V + I VA G T V + Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRI--VAGITGATGAVAGAY 119 Query: 329 VSEFFGLNNLAKNYGVIYLGFGIGSICGSIIASLFGGF--YVTFYVIFALLILSLALSTT 386 +++ + A+++G + FG G + G ++ L GGF + F+ AL L+ Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCF 179 Query: 387 IRQPEQK 393 + K Sbjct: 180 LLPESHK 186
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.5 bits (61), Expect = 0.045 Identities = 22/117 (18%), Positives = 47/117 (40%), Gaps = 16/117 (13%) Query: 119 SMYNEFGDSTTTLTDPLWHASVSTLGWRVDSRLGDLRPWAQISYNQQFGENIWKAQSGLS 178 S+ + D+ + H S + + + R G++ P ++SY F + Sbjct: 228 SVAVQQQDAKLV-EENYSHNSQTEVAATLAYRFGNVTP--RVSYAHGFKGSF-------- 276 Query: 179 RMTATNQNGNWLDVTVGADMLLNQNIAAYAA---LSQAENTTNNSDYLYTMGVSARF 232 ATN N ++ V VGA+ ++ +A + L + + + +G+ +F Sbjct: 277 --DATNYNNDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.1 bits (83), Expect = 1e-05 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 5/52 (9%) Query: 76 VAPKAVRRGIGKALM----QYVQQRHP-HLMLEVYQKNQPAIDFYHAQGFHI 122 VA ++G+G AL+ ++ ++ H LMLE N A FY F I Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 113 bits (285), Expect = 2e-32 Identities = 41/122 (33%), Positives = 62/122 (50%), Gaps = 11/122 (9%) Query: 108 LNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEY--PKTAVNVIGYTDSTGGHDLNMRLS 165 + ++V F+ + ATLKP G L + L +V V+GYTD G N LS Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLS 274 Query: 166 QQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGK---------AQNRRVEITL 216 ++RA SV LI++G+ A +I +G+G +NP+ N+ K A +RRVEI + Sbjct: 275 ERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 217 SP 218 Sbjct: 335 KG 336
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.1 bits (65), Expect = 0.025 Identities = 13/97 (13%), Positives = 33/97 (34%) Query: 315 QKQAITTAVTSIEKALEINPSNSQALGLLGLISGLKDEHSVSNVLFKQAHLLKPNSPDVY 374 Q A + ++ +S+ LG ++ ++ + ++ P Sbjct: 48 QSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFP 107 Query: 375 YYQSLLYFLNGDLARAFNLIEKSIALEPNKMGISILK 411 ++ + G+LA A + + + L +K L Sbjct: 108 FHAAECLLQKGELAEAESGLFLAQELIADKTEFKELS 144
>INTIMIN#Intimin signature. Length = 939 Score = 538 bits (1386), Expect = e-167 Identities = 200/789 (25%), Positives = 332/789 (42%), Gaps = 65/789 (8%) Query: 144 QVAEMAQQSGTLLARDMDSEQAASMARGWVASSASAQATDWLSRWGTARVSLGVDEDFSL 203 Q A + Q L +R ++ + A A G + AS+Q WL +GTA V+L +F Sbjct: 169 QAASLGSQ---LQSRSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD- 224 Query: 204 KSSSFEFLHPWYETPDNLVFSQHTLHRTDDRTQTNHGIGWRYFTSSWMSGVNMFIDHDLT 263 SS +FL P+Y++ L F Q D R N G G R+F M G N+FID D + Sbjct: 225 -GSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFS 283 Query: 264 RYHTRTGMGVEYWRDYLKLSGNGYLRLSNWRSAPELDNDYEARPANGWDLRAEGWLPAWP 323 +TR G+G EYWRDY K S NGY R+S W + DY+ RPANG+D+R G+LP++P Sbjct: 284 GDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYN-KKDYDERPANGFDIRFNGYLPSYP 342 Query: 324 QLGGKLVYEQYYGDEVALFGKDERQNDPHAITAGLSYTPVPLISFSAEQRQGKQGENDTR 383 LG KL+YEQYYGD VALF D+ Q++P A T G++YTP+PL++ + R G END Sbjct: 343 ALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLL 402 Query: 384 IGMELTLQPGHSLQKQLDPAEVAARRSLVGSRYDLVDRNNNIVLEYRKKELVRLTLTDPL 443 M+ Q +Q++P V R+L GSRYDLV RNNNI+LEY+K++++ L + + Sbjct: 403 YSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDI 462 Query: 444 KGKPGEVKSLVSSLQTKYALKGYDIEAASLQSAGGKVAVSG----KDIQVTIPPYRFTAM 499 G + + +++KY L + ++L+S GG++ SG +D Q +P Y + Sbjct: 463 NGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAY----V 518 Query: 500 PETDNTYPIAVTAEDSKGNFSRREE-SMVVVEKPTLSLTDSTLSVDQQILLADGKSTSTL 558 N Y + A D GN S ++ V+ + A T + Sbjct: 519 QGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAI 578 Query: 559 TYTA------RDSSGKPIPGMTLKTQVKGLQDFALSEWKDNGNGTYTQIVTAGKTSGALS 612 TYTA + P+ V G + + NG+G T + + K + Sbjct: 579 TYTATVKKNGVAQANVPVSFNI----VSGTAVLSANSANTNGSGKATVTLKSDKPGQVVV 634 Query: 613 LMPQFNGDDIAKTPALIAIVANTASRADSTIETDQDNYVAGKPIVVKVTLRDD-NGNGVT 671 A+I + AS + I+ D+ VA + T++ V+ Sbjct: 635 SAKTAEMTSALNANAVIFVDQTKASI--TEIKADKTTAVANGQDAITYTVKVMKGDKPVS 692 Query: 672 GRKELLKQTVKVDNTKADDVSAWTEESEGIYKASYTAHLIGDKLTA------QLTMPGWQ 725 ++ T+ + + ++ G K + T+ G L + + + + Sbjct: 693 NQEVTFTTTLGKLSNSTE-----KTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPE 747 Query: 726 TKHSDAFSIAGDKDTAKIAAMQITANNAVARRDHNTVAVTVRDVHQNLLQGQNVTFTVVN 785 + +I ++ + + + + T+ N Sbjct: 748 VEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNG--------KYTWRSAN 799 Query: 786 GAAVFADPNGGIVTTDKDGIASVNLASDQAVNSLIKAEINGSSQSVEVSFITGDISQLTS 845 A D + G VT + G ++++ S +Q+ + T + S + Sbjct: 800 PAIASVDASSGQVTLKEKGTTTISVIS-------------SDNQTATYTIATPN-SLIVP 845 Query: 846 TIKTDDVSYTAGGKIKVSVTLMDEQKNLVKGMASLLAGSSVVEVSGTDKNETG----NWS 901 + A K + +N ++ + ++ E + + Sbjct: 846 NMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAANKYEYYKSSQTIISWVQQTAQ 905 Query: 902 EESDGVYTT 910 + GV +T Sbjct: 906 DAKSGVAST 914 Score = 88.2 bits (218), Expect = 3e-19 Identities = 79/419 (18%), Positives = 140/419 (33%), Gaps = 31/419 (7%) Query: 1425 VTASINNSSQSQNVTFVADV-------RTAKIADLVVSQDNAVADGSTANTLRARVTDAF 1477 A N + S NV V + D + +A ADG+ A T A V Sbjct: 529 ARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKN- 587 Query: 1478 GNTLAGQTVSVMAGNGATV--APTVITEPDGTAEISVTSQTAGVSAVTASINNSSQSRDV 1535 G A VS +G V A + T G A +++ S G V+A + + + Sbjct: 588 GVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNA 647 Query: 1536 TF--IADIRTAQIASLEVTQDNAVADGAMANTLQVRVTDANGNTLAGQAVSVMAGNGATV 1593 D A I ++ + AVA+G A T V+V ++ Q V+ G Sbjct: 648 NAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMK-GDKPVSNQEVTFTTTLGKLS 706 Query: 1594 APAVTTQPDGTVEIPVTSQTAGASAVTASINNSSLSRDVTFIADVRTAQIAELVVIKDGS 1653 T +G ++ +TS T G S V+A +++ ++ + T I + + G+ Sbjct: 707 NSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGT 766 Query: 1654 AADGAT-ANTLQARVTDAFGNALAGQTVSVLADNSATVAPAVITEPDGTVDISVTSQTAG 1712 G LQ + + G+ A+ + A + G VT + G Sbjct: 767 GVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAI----ASVDASSG----QVTLKEKG 818 Query: 1713 ISTVTATINNHSLSQSVMFIADVRTAQIADLVVIKDGSEADGATANTLRARVTDAFGNAL 1772 +T++ ++ +Q+ + + I + K + D + N L Sbjct: 819 TTTISVISSD---NQTATYTIATPNSLIV-PNMSKRVTYNDAVNTCKNFGGKLPSSQNEL 874 Query: 1773 AGQTVSVLADNG-----ATVAPTVITGQDGTVEISVTSQTAGISTVTATINSSSQSQNV 1826 + A N ++ Q S + T + N + N Sbjct: 875 ENVFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVASTYDLVKQNPLNNIKASESNA 933 Score = 77.8 bits (191), Expect = 5e-16 Identities = 50/190 (26%), Positives = 79/190 (41%), Gaps = 6/190 (3%) Query: 2026 ISTAQIADLVVIKDGSEADGATANTLRARVTDAFGNALAGQTVSVMAGNGATVAPAVT-- 2083 + + D K ++ADG A T A V G A A VS +G V A + Sbjct: 555 VDQVGVTDFTADKTSAKADGTEAITYTATVKKN-GVAQANVPVSFNIVSGTAVLSANSAN 613 Query: 2084 TQPDGTVEISVTSQTAGISAVTASINSSSQSRDVTF--IADVRTAKIAELEVIRDNAVAD 2141 T G +++ S G V+A + + + D A I E++ + AVA+ Sbjct: 614 TNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVAN 673 Query: 2142 GSTANTLQVKVTDANGNTLAGQTVSVLAGNSATVASTVTTKPDGTVEISVTSQTAGTSTV 2201 G A T VKV ++ Q V+ ST T +G ++++TS T G S V Sbjct: 674 GQDAITYTVKVMK-GDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLV 732 Query: 2202 SASINNSSQS 2211 SA +++ + Sbjct: 733 SARVSDVAVD 742 Score = 75.5 bits (185), Expect = 2e-15 Identities = 62/347 (17%), Positives = 110/347 (31%), Gaps = 21/347 (6%) Query: 1638 VRTAQIAELVVIKDGSAADGATANTLQARVTDAFGNALAGQTVSVLADNSATVAPAVI-- 1695 V + + K + ADG A T A V G A A VS + V A Sbjct: 555 VDQVGVTDFTADKTSAKADGTEAITYTATVKKN-GVAQANVPVSFNIVSGTAVLSANSAN 613 Query: 1696 TEPDGTVDISVTSQTAGISTVTATINNH--SLSQSVMFIADVRTAQIADLVVIKDGSEAD 1753 T G +++ S G V+A +L+ + + D A I ++ K + A+ Sbjct: 614 TNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVAN 673 Query: 1754 GATANTLRARVTDAFGNALAGQTVSVLADNGATVAPTVITGQDGTVEISVTSQTAGISTV 1813 G A T +V ++ Q V+ G T T +G ++++TS T G S V Sbjct: 674 GQDAITYTVKVMKG-DKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLV 732 Query: 1814 TATINSSSQSQNVTFIADVRTAQIAELVVIKDGSAADGVMANMLRARVTDAFGNALAGQT 1873 +A ++ + + L + D ++ V Sbjct: 733 SARVSDVAVD-----VKAPEVEFFTTLTI-------DDGNIEIVGTGVKGKLPTVWLQYG 780 Query: 1874 VSVLAGNGATTAPTVTTQPDGTVEISVTSQTAGISAVTASINN--SSQSRNVTFIADVRT 1931 L +G T + + +S + + + SS ++ T+ Sbjct: 781 QVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPN 840 Query: 1932 AQIADLVVIKDGSEADGATANTLRARVTDAFGNALAGQTVSVTAGNG 1978 + I + K + D + N L + A N Sbjct: 841 SLIV-PNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAANK 886 Score = 74.7 bits (183), Expect = 5e-15 Identities = 64/350 (18%), Positives = 115/350 (32%), Gaps = 27/350 (7%) Query: 1250 VRTAQIADLVVIKDGSEADGATANTLRARVTDAFGNALAGQTVSVLADNGATVAPVVT-- 1307 V + D K ++ADG A T A V G A A VS +G V + Sbjct: 555 VDQVGVTDFTADKTSAKADGTEAITYTATVKKN-GVAQANVPVSFNIVSGTAVLSANSAN 613 Query: 1308 TQPDGTVEISVTSQTAGSSAVTVSINSSSQSRDVTF--IADVRTAQIADLVVIKDDSVAD 1365 T G +++ S G V+ + + + D A I ++ K +VA+ Sbjct: 614 TNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVAN 673 Query: 1366 GAMANMLRARVSDVFGNALAGQTVSVMADNGAAVASTMTTKPDGTVEISVTSQTAGISVV 1425 G A +V ++ Q V+ G ST T +G ++++TS T G S+V Sbjct: 674 GQDAITYTVKV-MKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLV 732 Query: 1426 TASINNSSQSQNVTFVADVRTAKIADLVVSQDNAVADGSTANTLRARVTDAFGNTLAGQT 1485 +A +++ + V L + D + V Sbjct: 733 SARVSDVAVD-----VKAPEVEFFTTLTI-------DDGNIEIVGTGVKGKLPTVWLQYG 780 Query: 1486 VSVMAGNGATVAPTVITEPDGTAEIS-----VTSQTAGVSAVTASINNSSQSRDVTFIAD 1540 + +G T + A + VT + G + ++ SS ++ T+ Sbjct: 781 QVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVI---SSDNQTATYTIA 837 Query: 1541 IRTAQIASLEVTQDNAVADGAMANTLQVRVTDANGNTLAGQAVSVMAGNG 1590 + I +++ D ++ N L + A N Sbjct: 838 TPNSLIV-PNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAANK 886 Score = 71.3 bits (174), Expect = 5e-14 Identities = 73/374 (19%), Positives = 125/374 (33%), Gaps = 30/374 (8%) Query: 1812 TVTATINSSSQSQNVTFIADVRTAQ-------IAELVVIKDGSAADGVMANMLRARVTDA 1864 T A + + S NV V + + + K + ADG A A V Sbjct: 528 TARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKN 587 Query: 1865 FGNALAGQTVSVLAGNGATT--APTVTTQPDGTVEISVTSQTAGISAVTASINNSSQSRN 1922 G A A VS +G A + T G +++ S G V+A + + N Sbjct: 588 -GVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALN 646 Query: 1923 VTF--IADVRTAQIADLVVIKDGSEADGATANTLRARVTDAFGNALAGQTVSVTAGNGAT 1980 D A I ++ K + A+G A T +V ++ Q V+ T G Sbjct: 647 ANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKG-DKPVSNQEVTFTTTLGKL 705 Query: 1981 VAPTVTTQPDGTAEISVTSQTAGVSAVTASINNSSQSRDVTFIADISTAQIADLVVIKDG 2040 T T +G A++++TS T G S V+A +++ + + +T I D + G Sbjct: 706 SNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVG 765 Query: 2041 SEADGATANTLRARVTDAFGNALAGQTVSVMAGNGATVAPAVTTQPDGTVEIS---VTSQ 2097 + G GQ +G +V+ S VT + Sbjct: 766 TGVKGKLPTVWLQY----------GQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLK 815 Query: 2098 TAGISAVTASINSSSQSRDVTFIADVRTAKIAELEVIRDNAVADGSTANTLQVKVTDANG 2157 G + ++ SS ++ T+ + I + + D ++ Sbjct: 816 EKGTTTISV---ISSDNQTATYTIATPNSLIV-PNMSKRVTYNDAVNTCKNFGGKLPSSQ 871 Query: 2158 NTLAGQTVSVLAGN 2171 N L + A N Sbjct: 872 NELENVFKAWGAAN 885 Score = 69.7 bits (170), Expect = 1e-13 Identities = 76/379 (20%), Positives = 138/379 (36%), Gaps = 26/379 (6%) Query: 1035 NALTSNDYSISGDAASAQIVAMQV-----TTGNPDVLANGSDRHTVNVRVEDQFGNVLSE 1089 N +SN+ ++ S V QV T A+G++ T V+ G + Sbjct: 535 NGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKN-GVAQAN 593 Query: 1090 QTVTFTVTKGAAVFANAGQSADIRTDAHGMAEVDLSSTVADASTVEAKINQSSDSKTVNF 1149 V+F + G AV + + T+ G A V L S V AK + + + N Sbjct: 594 VPVSFNIVSGTAVLS----ANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANA 649 Query: 1150 V--ADVSTAQVAELVVTQDGSVADGSTANTLRARVTDVFGNALAGQTVSVLAGNGATTAP 1207 V D + A + E+ + +VA+G A T +V ++ Q V+ G + Sbjct: 650 VIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKG-DKPVSNQEVTFTTTLGKLSNS 708 Query: 1208 TVTTQPDGTVEISVTSQTAGTSVITASVNNSSQSRDVTFIADVRTAQIADLVVIKDGSEA 1267 T T +G ++++TS T G S+++A V++ + + T I D + G+ Sbjct: 709 TEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGV 768 Query: 1268 DGAT-ANTLRARVTDAFGNALAGQTVSVLADNGATVAPVVTTQPDGTVEISVTSQTAGSS 1326 G L+ + + G+ A+ +A V + VT + G++ Sbjct: 769 KGKLPTVWLQYGQVNLKASGGNGKYTWRSANPA--IASVDASSG------QVTLKEKGTT 820 Query: 1327 AVTVSINSSSQSRDVTFIADVRTAQIADLVVIKDDSVADGAMANMLRARVSDVFGNALAG 1386 ++V SS ++ T+ + I + K + D N L Sbjct: 821 TISV---ISSDNQTATYTIATPNSLIV-PNMSKRVTYNDAVNTCKNFGGKLPSSQNELEN 876 Query: 1387 QTVSVMADNGAAVASTMTT 1405 + A N + T Sbjct: 877 VFKAWGAANKYEYYKSSQT 895 Score = 66.6 bits (162), Expect = 1e-12 Identities = 76/428 (17%), Positives = 130/428 (30%), Gaps = 71/428 (16%) Query: 1657 GATANTLQARVTDAFGNALAGQTVSVLADNSATVAPAVITEPDGTVDISVTSQTAGISTV 1716 G+ + AR D GN + N+ + V++ + VT TA Sbjct: 521 GSNVYKVTARAYDRNGN----------SSNNVLLTITVLSNGQVVDQVGVTDFTAD---- 566 Query: 1717 TATINNHSLSQSVMFIADVRTAQIADLVVIKDGSEADGATANTLRARVTDAFGNALAGQT 1776 K ++ADG A T A V G A A Sbjct: 567 ------------------------------KTSAKADGTEAITYTATVKKN-GVAQANVP 595 Query: 1777 VSVLADNGATV--APTVITGQDGTVEISVTSQTAGISTVTATINSSSQSQNVTF--IADV 1832 VS +G V A + T G +++ S G V+A + + N D Sbjct: 596 VSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQ 655 Query: 1833 RTAQIAELVVIKDGSAADGVMANMLRARVTDAFGNALAGQTVSVLAGNGATTAPTVTTQP 1892 A I E+ K + A+G A +V ++ Q V+ G + T T Sbjct: 656 TKASITEIKADKTTAVANGQDAITYTVKVMKG-DKPVSNQEVTFTTTLGKLSNSTEKTDT 714 Query: 1893 DGTVEISVTSQTAGISAVTASINNSSQSRNVTFIADVRTAQIADLVVIKDGSEADGATAN 1952 +G ++++TS T G S V+A +++ + + L + D Sbjct: 715 NGYAKVTLTSTTPGKSLVSARVSDVAVD-----VKAPEVEFFTTLTI-------DDGNIE 762 Query: 1953 TLRARVTDAFGNALAGQTVSVTAGNGATVAPTVTTQPDGTAEIS-----VTSQTAGVSAV 2007 + V +G T + A + VT + G + + Sbjct: 763 IVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTI 822 Query: 2008 TASINNSSQSRDVTFIADISTAQIADLVVIKDGSEADGATANTLRARVTDAFGNALAGQT 2067 + SS ++ T+ + I + K + D + N L Sbjct: 823 SVI---SSDNQTATYTIATPNSLIV-PNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVF 878 Query: 2068 VSVMAGNG 2075 + A N Sbjct: 879 KAWGAANK 886 Score = 54.3 bits (130), Expect = 7e-09 Identities = 57/323 (17%), Positives = 103/323 (31%), Gaps = 38/323 (11%) Query: 885 SVVEVSGTDKNETGNWSEESDGVYTTTRTAKIAGDRHYATLKLSTWSSAQQSDAYAIRES 944 S VSGT + + G T T + G + + K + +SA ++A + Sbjct: 597 SFNIVSGTAVLSANSANTNGSGKATVTLKSDKPG-QVVVSAKTAEMTSALNANAVIFVDQ 655 Query: 945 GAVLAYSSIVTDKTAYTAGGAIKVTVTLKDSY-ENLVGGQRDAINLAIQLPNTKAESIAW 1003 + + I DKT A G +T T+K + V Q + + E Sbjct: 656 TKA-SITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEK--- 711 Query: 1004 NEDQKGIYTATYTALLPGTGLKAQLQMSGWANALTSNDYSISGDAASAQIVAMQVTTGNP 1063 D G T T+ PG L + ++S A + + + + + GN Sbjct: 712 -TDTNGYAKVTLTSTTPGKSLVSA-RVSDVAVDVKAPEVEFFTT--------LTIDDGNI 761 Query: 1064 DVLANGSDRHTVNVRVE-DQFGNVLSEQTVTFTVTKGAAVFANAGQSADIRTDAHGMAEV 1122 +++ G V ++ Q S +T +A V Sbjct: 762 EIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANP----------------AIASV 805 Query: 1123 DLSS---TVADASTVEAKINQSSDSKTVNFVADVSTAQVAELVVTQDGSVADGSTANTLR 1179 D SS T+ + T + SSD++T + + + +++ + D Sbjct: 806 DASSGQVTLKEKGTTTISVI-SSDNQTATYTIATPNSLIV-PNMSKRVTYNDAVNTCKNF 863 Query: 1180 ARVTDVFGNALAGQTVSVLAGNG 1202 N L + A N Sbjct: 864 GGKLPSSQNELENVFKAWGAANK 886 Score = 38.9 bits (90), Expect = 4e-04 Identities = 25/127 (19%), Positives = 44/127 (34%), Gaps = 9/127 (7%) Query: 2446 EPLTVTITLRDEFGNPALGLTSEVIESYIDSFAVGGATPDSMRWVEQNNGEYTIVWTAWI 2505 E +T T T++ A S I S G A + +G+ T+ + Sbjct: 576 EAITYTATVKKNGVAQANVPVSFNIVS-------GTAVLSANSANTNGSGKATVTLKSD- 627 Query: 2506 AEENLVASLKLKTWAEEIKSSLYGIQPGAAAKTQSTIVADKTIYIAGDSITVTVVLKDAQ 2565 +V S K + ++ A + + I ADKT +A +T +K + Sbjct: 628 KPGQVVVSAKTAEMTSALNANAVIFVDQTKA-SITEIKADKTTAVANGQDAITYTVKVMK 686 Query: 2566 GNFITDG 2572 G+ Sbjct: 687 GDKPVSN 693
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 37.9 bits (88), Expect = 6e-05 Identities = 33/208 (15%), Positives = 71/208 (34%), Gaps = 13/208 (6%) Query: 33 IIVEFLPVSLLTP----MAQDLGISEGVA---GQSVTVTAFVAMFASLFITQTIQATDRR 85 + ++ + + L+ P + +DL S V G + + A + + + RR Sbjct: 14 VALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRR 73 Query: 86 YVVILFAVLLTLSCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKA 145 V+++ + +++ A +L IGR G+ G A++ + + + Sbjct: 74 PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARH 132 Query: 146 LSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAVMG----VLCIFWIIKSLPSLPGE 201 + +V LG +G F AAA + + F + +S Sbjct: 133 FGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP 191 Query: 202 PSHQKQNTFRLLQRPGVMAGMIAIFMSF 229 + N + M + A+ F Sbjct: 192 LRREALNPLASFRWARGMTVVAALMAVF 219
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 38.2 bits (89), Expect = 9e-05 Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 17/105 (16%) Query: 22 AVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVG----------AEYTDAPA 71 V+R D +I N ILD + G + I +K IA +G P Sbjct: 60 QVTREGGAVDTVITNALILD--HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPG 117 Query: 72 LQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVI 116 + I G G +D+H+H + P E A L GLT ++ Sbjct: 118 TEVIAGEGKIVTAGGMDSHIH----FICPQQIEEA-LMSGLTCML 157
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 59.9 bits (145), Expect = 6e-12 Identities = 41/184 (22%), Positives = 81/184 (44%), Gaps = 1/184 (0%) Query: 5 RNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGAVQSVMGAYLLTYGVSQLFYG 64 R+ +L+ L +L + + + ++ D+A D N + V A++LT+ + YG Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 65 PISDRVGRRPVILVGMSIFMLATLVA-VTTSSLTVLIAASAMQGMGTGVGGVMARTLPRD 123 +SD++G + ++L G+ I +++ V S ++LI A +QG G + + Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 124 LYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWNWRACYLFLLVLCAGVTFSMARWM 183 + A L+ + + + P IGG++ +W L ++ V F M Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLK 190 Query: 184 PETR 187 E R Sbjct: 191 KEVR 194
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.4 bits (66), Expect = 0.022 Identities = 38/172 (22%), Positives = 67/172 (38%), Gaps = 17/172 (9%) Query: 162 TAGIASFEPHVFVGAVLPFLVGFA-LGNLDPELREFFSKAVQTLIPF-FAFALGNTID-L 218 I +F +L FLV + L N+ L + V L F A G +I+ L Sbjct: 334 QLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTL 393 Query: 219 TVIAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAV--ATPVLIA 276 T+ +G+L+ A+++V + ++ + A + S A+ VL A Sbjct: 394 TMFGMVLAIGLLVDDAIVVVENVERVMMED--KLPPKEATEKSMSQIQGALVGIAMVLSA 451 Query: 277 EMVPA----------FKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKAR 318 +P ++ + S +A +V+V IL P L + + V A Sbjct: 452 VFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAE 503
>PF06580#Sensor histidine kinase Length = 349 Score = 29.4 bits (66), Expect = 0.027 Identities = 28/186 (15%), Positives = 63/186 (33%), Gaps = 33/186 (17%) Query: 277 IETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEV-LDNAAFEAEQM--GKSLT 333 I + + M+ L + R + + + L E+ + ++ + + L Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQV----SLADELTVVDSYLQLASIQFEDRLQ 241 Query: 334 VNF--PPGPWPLYGNPNALESALENIVRNAL--RYSHTKIEVGFAVDKDGITITVDDDGP 389 P + P +++ +EN +++ + KI + D +T+ V++ G Sbjct: 242 FENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS 301 Query: 390 GVSPEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGW---VKAEDSPLGGLR 446 +E TG GL V +Q G +K + G + Sbjct: 302 LALKNTKE------------------STGTGLQNVRERLQMLYGTEAQIKLSEKQ-GKVN 342 Query: 447 LVIWLP 452 ++ +P Sbjct: 343 AMVLIP 348
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.020 Identities = 12/22 (54%), Positives = 13/22 (59%) Query: 32 MVALLGPSGSGKSTLLRHLSGL 53 V L G G GKSTL+ L GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 26.5 bits (58), Expect = 0.045 Identities = 11/42 (26%), Positives = 23/42 (54%) Query: 66 IAGSDIMMSDAIPSGKASYSGFTLVLDSQQVEEGKRWFDNLA 107 I+GS+ + S + + Y G + ++Q + +R+F NL+ Sbjct: 189 ISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLS 230
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 43.3 bits (102), Expect = 1e-06 Identities = 57/290 (19%), Positives = 105/290 (36%), Gaps = 55/290 (18%) Query: 85 FFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGE 144 G L D++GR+ +L +++ ++ + P +W +L I ++ G + G Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF-----LW---VLYIGRIVAGIT-GAT 112 Query: 145 YTGASIFVAEYSPDRKR----GFMGSWLDFGSIAGFVLGAGVVVLISTIVGEENFLDWGW 200 A ++A+ + +R GFM + FG +AG VLG G++ S Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG-GLMGGFSP------------ 159 Query: 201 RIPFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRS 260 PFF A L + L K E+ P SF+ W Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESH------KGERRPLRREALNPLASFR------WAR 207 Query: 261 LLTCIGLVIATNVTYYML----LTYMPSYLSHNLHYS-EDHGVLIIIAIMIGMLFVQPVM 315 +T + ++A ++ + H+ G+ + ++ L + Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMIT 267 Query: 316 GLLSDRFGRRPFVLLG----SVALFVLA--------IPAFILINSNVIGL 353 G ++ R G R ++LG +LA P +L+ S IG+ Sbjct: 268 GPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM 317 Score = 39.0 bits (91), Expect = 3e-05 Identities = 39/164 (23%), Positives = 73/164 (44%), Gaps = 16/164 (9%) Query: 286 LSHNLHYSEDHGVLI-IIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVALFVLAIPAFI 344 L H+ + +G+L+ + A+M PV+G LSDRFGRRP +L+ L A+ I Sbjct: 35 LVHSNDVTAHYGILLALYALM--QFACAPVLGALSDRFGRRPVLLVS---LAGAAVDYAI 89 Query: 345 LINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIR---YSALAAAFNISVLVAG 401 + + + +++ G ++A I V + + + R + ++A F +VAG Sbjct: 90 MATAPFLWVLYIG-RIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFG-MVAG 147 Query: 402 LTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITG-VTMKETANR 444 P L + S + P + + + +TG + E+ Sbjct: 148 --PVLGGLMGGFSPH--APFFAAAALNGLNFLTGCFLLPESHKG 187
>PF06580#Sensor histidine kinase Length = 349 Score = 36.8 bits (85), Expect = 1e-04 Identities = 40/182 (21%), Positives = 80/182 (43%), Gaps = 34/182 (18%) Query: 184 ARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDV-ILPSYDELSTML--DQRQQTLL 240 + +M+ S+S+L++ S N + V L +++ ++ SY +L+++ D+ Q Sbjct: 191 TKAREMLTSLSELMR-----YSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 241 LPESAADITVQGDATLLRMLLRNLVENAHRY----SPQGSNIMIKLQEDGGAV-MAVEDE 295 + + D+ V ML++ LVEN ++ PQG I++K +D G V + VE+ Sbjct: 246 INPAIMDVQV------PPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 296 GPGIDESKCGELSKAFVRMDSRYGGIGLGLSIV-SRITQLHHGQFFLQNRQETSGTRAWV 354 G + + G GL V R+ L+ + ++ ++ A V Sbjct: 300 GSLA--------------LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 355 RL 356 + Sbjct: 346 LI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.7 bits (225), Expect = 2e-23 Identities = 41/121 (33%), Positives = 60/121 (49%) Query: 2 KILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLGLPDEDGLH 61 IL+ +DD + L A GY + A + + AG LVV D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 FLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRRHNN 121 L RI++ + LPVL+++A++T I + GA DYL KPF L EL I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 Q 122 + Sbjct: 125 R 125
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 29.2 bits (65), Expect = 0.014 Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 4/45 (8%) Query: 145 PLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLW 189 P +V GIA G V T+ GL W ++ N D + +W Sbjct: 42 PAIVG-GIATGAAVGTVSGLLGWGLKQAEEAN---KTPDKPDKVW 82
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.5 bits (209), Expect = 4e-21 Identities = 33/139 (23%), Positives = 60/139 (43%) Query: 1 MRRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARQQVPDVMILDVGLPDI 60 M T+ + +D+ I L L + G+ V + + D+++ DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLR 120 + F+L ++ P LPVL ++A++ + + E GA DY+ KPF E+ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 RVKKFSTPSPVIRIGHFEL 139 K+ + L Sbjct: 121 EPKRRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 36.0 bits (83), Expect = 3e-04 Identities = 41/182 (22%), Positives = 71/182 (39%), Gaps = 40/182 (21%) Query: 312 LRQARLENRQEVVLTVVDVAALFR---RVSEARTVQLAE-----------------KKIT 351 +R LE+ + + ++ L R R S AR V LA+ ++ Sbjct: 182 IRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQ 241 Query: 352 LHV-MPTEVNVAAEPTLLEQAL-GNLLDNAIDFTPESGRITLSAEVEQEHVTLKVLDTGS 409 + + P +L Q L N + + I P+ G+I L + VTL+V +TGS Sbjct: 242 FENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS 301 Query: 410 GIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSE-VARLFNGEVTLH-NVQEGGVLASL 467 N ++S+G GL V E + L+ E + + ++G V A + Sbjct: 302 LALK----------------NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 468 RL 469 + Sbjct: 346 LI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 4e-20 Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Query: 1 MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGK 60 M IL+ +D+ R L GYDV ++ A + + ++ D +LV+ D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELRE-QANVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLS 119 N L +++ + ++ ++ ++ ++ + I E GA DY+ KPF+ EL L+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RT 121 Sbjct: 121 EP 122