>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 30.5 bits (69), Expect = 0.034 Identities = 16/32 (50%), Positives = 18/32 (56%), Gaps = 1/32 (3%) Query: 395 NILVTGL-GPAGFSLSYYLLRSGHNVTAIDGL 425 LVTG G GF +S LL +GH V ID L Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNL 33
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 81.1 bits (200), Expect = 6e-20 Identities = 54/243 (22%), Positives = 97/243 (39%), Gaps = 26/243 (10%) Query: 18 AKPKIVVSITPIASIVSMLVKDKADIKSLAISSDCPHHYNLKPSDLAKVKNADIAIYI-- 75 K K+V + + IA I + DK D+ S+ PH Y P D+ K AD+ Y Sbjct: 31 QKLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGI 90 Query: 76 ------NEQFDGFAKKLIDNHSQNIIKISDIKSLTSI-------KDNWHIWLDLNNSAIL 122 N F + +++ +SD + + K++ H WL+L N I Sbjct: 91 NLETGGNAWFTKLVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIF 150 Query: 123 LQEFAQIFSEKFPALQEDINNNLSAALKELNKL-KEIKN---NALASLKDVILLSDSTEY 178 + A+ S K P +E NL +L+KL KE K+ A K ++ + +Y Sbjct: 151 AKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKY 210 Query: 179 FFLNTNIKTAKLY---SESQKSLQYISNLEALIKGSNNKCLVL----SNKQTSQLYDKLN 231 F + +A ++ +E + + + I L ++ + L + ++ + N Sbjct: 211 FSKAYGVPSAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTN 270 Query: 232 TKI 234 I Sbjct: 271 IPI 273
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 35.8 bits (82), Expect = 0.001 Identities = 37/222 (16%), Positives = 82/222 (36%), Gaps = 16/222 (7%) Query: 242 KAKKSAQKKAPVAEVSTAGPFLNQQRQLDVLTQKQKVNAVRQAAVNKKKRRENEVKRNST 301 KA + AQKK A+ + L+ R A + + NE+ + S Sbjct: 189 KAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSS---SIHARDAEMKTLAGKRNELAQASA 245 Query: 302 DVEKLITQMNQVQLEQN---QRRIAAE-LQRKAETSTKHVTIKNKNKSKADKVRQEKTFL 357 ++L + ++ N Q R E +R+ + + + ++ + Sbjct: 246 KYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINR----- 300 Query: 358 QKIHLTKTEQEKKIAEDKNARAAAEKVRKEKNKQAQKAEEISNIKLKVSEQLIQMLDYKA 417 I+ T+ +K I++ N R A E ++ K + + + ++ + + + + Sbjct: 301 --INADITQIQKAISQVSNNRNAGIARVHEA-EENLKKAQNNLLNSQIKDAVDATVSFYQ 357 Query: 418 KLQEKLQEVERIEAKHEVSVIK-KELKNIEKLVSKAAKVVNN 458 L EK E A+ K K++ N+ + ++ K + Sbjct: 358 TLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDV 399 Score = 31.2 bits (70), Expect = 0.035 Identities = 35/181 (19%), Positives = 67/181 (37%), Gaps = 7/181 (3%) Query: 234 AIEQTSGKKAKKSAQKKAPVAEVSTAGPFLNQQRQLDVLTQKQKVNAVRQ--AAVNKKKR 291 A +T K + AQ A E+ L+ R D L + A R+ A ++ Sbjct: 228 AEMKTLAGKRNELAQASAKYKELDELVKKLSP-RANDPLQNRPFFEATRRRVGAGKIREE 286 Query: 292 RENEVKRNSTDVEKLITQMNQVQ----LEQNQRRIAAELQRKAETSTKHVTIKNKNKSKA 347 ++ +V + T + ++ + Q+Q N R +AE + K N Sbjct: 287 KQKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIK 346 Query: 348 DKVRQEKTFLQKIHLTKTEQEKKIAEDKNARAAAEKVRKEKNKQAQKAEEISNIKLKVSE 407 D V +F Q + E+ K+A++ ++ +K+ A + + K S+ Sbjct: 347 DAVDATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDVLNKKFSK 406 Query: 408 Q 408 Sbjct: 407 A 407
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 225 bits (575), Expect = 5e-76 Identities = 67/201 (33%), Positives = 100/201 (49%), Gaps = 7/201 (3%) Query: 53 YDPYEKFNRKVFAFN-SALDYIILRPLAVGYKNITNDYVKARVNSLVSNIDTLLTAVNYG 111 DP E FNR ++ FN + LD I+RP+AV +++ + +++ N++ VNY Sbjct: 29 SDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYF 88 Query: 112 LQLNYDKTMKSVWRFLINTTLGIGGLFDVAGKVGLPSDR---QTFGNTLAHYGVAPGPYL 168 LQ + + M RF +NT LG+GG DVAG R FG+TL HYGV GPY+ Sbjct: 89 LQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYV 148 Query: 169 VLPIIGSTNARDMTDLIFTNYVLNPLMYYTRNDFELGVLVVSKINNRCVVLPFSDYVMKN 228 LP GS RD D L P++ + +G + I R L SD +++ Sbjct: 149 QLPFYGSFTLRD--DGGDMADALYPVLSWLTWPMSVGKWTLEGIETR-AQLLDSDGLLRQ 205 Query: 229 STDPYVAIRSALHRAREASVQ 249 S+DPY+ +R A + + Sbjct: 206 SSDPYIMVREAYFQRHDFIAN 226
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 255 bits (653), Expect = 5e-85 Identities = 104/357 (29%), Positives = 169/357 (47%), Gaps = 21/357 (5%) Query: 8 INLSAIKNNYFLLQDICKTSLVGAVVKADGYGLGAVQISKALIEENCRHFFVASSEEGVN 67 ++L A+K N +++ + V +VVKA+ YG G +I A+ + F + + EE + Sbjct: 9 LDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDG--FALLNLEEAIT 66 Query: 68 VRKALGIDVNILVLNGVFEHDALELI-EYNLIPILNNLKQIEIWQQFGNLKNLLLPCYLH 126 +R+ G IL+L G F LE+ ++ L +++ Q++ Q LK L YL Sbjct: 67 LRER-GWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNA-RLKAPL-DIYLK 123 Query: 127 FNTGINRLGLSSNEIEQLINNRDLLKGLNLQYIISHLAISEEIDNPYNLEQLNKFKAYLR 186 N+G+NRLG + + + + + ++SH A +E D + + + Sbjct: 124 VNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISG--AMARIEQAAE 181 Query: 187 YFPSIKASLANSGGIFLGQDYHFDLVRPGAALYGLNPLMQN---------PV-TLKAPII 236 + SL+NS + HFD VRPG LYG +P Q PV TL + II Sbjct: 182 GLEC-RRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSEII 240 Query: 237 HLQNLTLDSHIGYNMTFTTKRDSVIATLPLGYADGYSRNFSNQGKVFINGRSVPIVGRVS 296 +Q L +GY +T + + I + GYADGY R+ V ++G VG VS Sbjct: 241 GVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGTVS 300 Query: 297 MDLINIDVTDLPPSDIFLGQEVEIIGNHCTPDKIASIIGTIGYEVLTSLGNRYRRKY 353 MD++ +D+T P +G VE+ G D +A+ GT+GYE++ +L R Sbjct: 301 MDMLAVDLTPCP--QAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRVPVVT 355
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 599 bits (1546), Expect = 0.0 Identities = 177/670 (26%), Positives = 295/670 (44%), Gaps = 66/670 (9%) Query: 10 IRNIGICAHIDAGKTTTTERILYYTGKSHKIGEVHEGGATMDWMEQEQERGITITSAATT 69 I NIG+ AH+DAGKTT TE +LY +G ++G V +G D E++RGITI + T+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 70 CRWQDKIINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVP 129 +W++ +NIIDTPGH+DF EV RSL VLDGA+ + GV+ Q+ ++ K +P Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 130 RMCFINKMDRMGADFYRCVEMIKDRLGAKPLVIQLPVGIEENFKGIIDLVKMKAVIWKDE 189 + FINK+D+ G D + IK++L A + VI + Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSA------------------------EIVIKQKV 158 Query: 190 SLGAEYFAEDIPADMKYKAEEYRTKLLDMVVELDDHIMEKYLSGEEVTEEEIERLIRNGT 249 L + ++E++ D V+E +D ++EKY+SG+ + E+E+ Sbjct: 159 ELYPNMCVTNFT-----ESEQW-----DTVIEGNDDLLEKYMSGKSLEALELEQEESIRF 208 Query: 250 ISAAFYPVLCGSAFKNKGVQPLLDAVVGFLPSPIDIGIVKGIEVSTGEEKDFPISVTEPF 309 + + +PV GSA N G+ L++ + S Sbjct: 209 HNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH-------------------RGQSEL 249 Query: 310 AALAFKIMNDPFVGSLTFIRIYSGKITSGSTVINTVKNKREKIGRMLLMHANNREDVKEA 369 FKI L +IR+YSG + +V + K K KI M + +A Sbjct: 250 CGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKIDKA 308 Query: 370 SAGDIVALAG----LKDTTTGDTLSDIDKQVILERMEFPEPVIELAVEPKSTADQEKMGL 425 +G+IV L L GDT + ER+E P P+++ VEP +E + Sbjct: 309 YSGEIVILQNEFLKLNS-VLGDTKLLPQR----ERIENPLPLLQTTVEPSKPQQREMLLD 363 Query: 426 ALSRLAAEDPSFRVSMDHETGQTVIKGMGELHLEIIIDRMRREFKVEANIGAPQVAYRET 485 AL ++ DP R +D T + ++ +G++ +E+ ++ ++ VE I P V Y E Sbjct: 364 ALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYMER 423 Query: 486 ITKICEIDYTHKKQSGGAGQFARVKIIFEPLNPGEGFVFESKIVGGAVPKEYIPGIEKGL 545 K E YT + +A + + PL G G +ES + G + + + + +G+ Sbjct: 424 PLKKAE--YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGI 481 Query: 546 NNIRETGVIAGYPMIDFKATLVDGAFHDVDSSVLAFEIAAKAAFREGMLKGNPKLLEPIM 605 E G + G+ + D K G ++ S+ F + A + + K +LLEP + Sbjct: 482 RYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYL 540 Query: 606 KVEVITPDEYMGDIIGDLNSRRGQIQSMDPRANAQVVTSNVPLAEMFGYVNTLRSLSQGR 665 ++ P EY+ D I + N +++ +P + Y + L + GR Sbjct: 541 SFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGR 600 Query: 666 AQFSMIFSHY 675 + Y Sbjct: 601 SVCLTELKGY 610
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 39.9 bits (93), Expect = 1e-07 Identities = 17/46 (36%), Positives = 25/46 (54%) Query: 27 KIYKFFEQVKQETYKVVWPTRKELVASTLVVVVAVFIFSLICLVLD 72 F + + E KV+WPTR+E + +TL+V + SLI LD Sbjct: 67 ATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLD 112
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 191 bits (486), Expect = 6e-55 Identities = 106/457 (23%), Positives = 190/457 (41%), Gaps = 68/457 (14%) Query: 9 IRNIAIIAHVDHGKTTLVDNMLKQSGTFRANQAVAE--RAMDSNDLERERGITILAKCTA 66 I NI ++AHVD GKTTL +++L SG +V + D+ LER+RGITI T+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 67 LMWNDIRINIVDTPGHADFGGEVERILSMVDGVVLLVDASEGPMPQTKFVLSKALNLSLK 126 W + ++NI+DTPGH DF EV R LS++DG +LL+ A +G QT+ + + + Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 127 PIVVINKIDRDDQRIKEVIDDVFELFVA----------------------------LEAN 158 I INKID++ + V D+ E A +E N Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182 Query: 159 NDQL-----DFPIVYASGRAGRAALTFDDKINP------LDNLADDLSPLFDLIVTHVPT 207 +D L + + + + P +N+ + L ++I + Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIG--IDNLIEVITNKFYS 240 Query: 208 PVADDKAPFSMLVTTREYNSFFGRVLTGRVQSGTVKINQNVKVLNRENKVLENGRITKIL 267 ++ V EY+ R+ R+ SG + + +V++ +E +IT++ Sbjct: 241 STHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-----KITEMY 295 Query: 268 AFRGLERIAIDEATAGDIIAMAGLE---NANVADTICSPEVTQAIPSLPIDPPTLSITFS 324 E ID+A +G+I+ + N+ + DT P + P P L T Sbjct: 296 TSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP--QRERIENP--LPLLQTTVE 351 Query: 325 VNDSPLAGSEGTKVTSSLIGNRLMREL-ESNVALKVTEAAEKNTFQVAGRGELQLGILIE 383 + + + +L E+ +S+ L+ + + ++ G++Q+ + Sbjct: 352 PSKP----QQREMLLDAL------LEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCA 401 Query: 384 TMRRE-GFELSISRPEVLFQTDENGNKQEPMEEIQVD 419 ++ + E+ I P V++ K E I+V Sbjct: 402 LLQEKYHVEIEIKEPTVIYMERPLK-KAEYTIHIEVP 437
>PF07675#Cleaved Adhesin Length = 1358 Score = 29.3 bits (65), Expect = 0.009 Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 1/40 (2%) Query: 56 DLSNIAVGQTVTVKWQGKPVFITNRTPDKIAAARAVKMSE 95 +L+ AVGQ VT+KW P N P+ +SE Sbjct: 597 NLTGSAVGQKVTLKWSA-PNGTPNPNPNPNPNPGTTTLSE 635
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 102 bits (256), Expect = 6e-25 Identities = 46/158 (29%), Positives = 78/158 (49%), Gaps = 14/158 (8%) Query: 7 IRNFSIIAHIDHGKSTLADRL------IEHCGGFQAREMSKQVLDSMDIEKERGITIKAQ 60 I N ++AH+D GK+TL + L I G D+ +E++RGITI+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDK---GTTRTDNTLLERQRGITIQTG 59 Query: 61 TVKLLYKAKDGNTYYLNLMDTPGHVDFAYEVSRSLAACEGSLLVVDSTQGVEAQTLANVY 120 + +N++DTPGH+DF EV RSL+ +G++L++ + GV+AQT + Sbjct: 60 ITSFQW-----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 121 KAIENNHEIVPVLNKIDLPASEPEHVKQQIEDIIGIDA 158 + + +NKID + V Q I++ + + Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEI 152 Score = 88.8 bits (220), Expect = 1e-20 Identities = 45/216 (20%), Positives = 83/216 (38%), Gaps = 18/216 (8%) Query: 165 SAKSGIGIDLVLEAIVNKLPPPKESSDDILKALLVDSWYDPYLGVVILVRIIDGALRKNM 224 SAK+ IGID ++E I NK L + Y + +R+ G L Sbjct: 220 SAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRD 279 Query: 225 RIKMMATNSV----YKVEHVGYFTPKKHIADVLYAGEIGFFTASIKQVADCKVGDTITDE 280 +++ + G D Y+GEI I Q K+ + D Sbjct: 280 SVRISEKEKIKITEMYTSINGELCK----IDKAYSGEIV-----ILQNEFLKLNSVLGDT 330 Query: 281 KKPCEQALPGFKPNLPVVFCGFYPTDSSEFEYLKDSLAKLHLNDSSFEYEMESSSALGVG 340 K ++ P++ P+ + E L D+L ++ +D Y ++S++ + Sbjct: 331 KLLPQRERIENPL--PLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEII- 387 Query: 341 FRCGFLGLLHLEIIQERLSREFDLDLITTAPSVIYK 376 FLG + +E+ L ++ +++ P+VIY Sbjct: 388 --LSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYM 421 Score = 35.2 bits (81), Expect = 8e-04 Identities = 13/80 (16%), Positives = 30/80 (37%), Gaps = 1/80 (1%) Query: 402 IEEPWIKAIIIVPDEFLGAVLSLCTEKRGVQLDHSYIANRARIVYKLPLNEIVYDFYDRL 461 + EP++ I P E+L + + +D N + ++P I ++ L Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCI-QEYRSDL 593 Query: 462 KSCSKGYASFEWQMDVYAPS 481 + G + ++ Y + Sbjct: 594 TFFTNGRSVCLTELKGYHVT 613
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 362 bits (930), Expect = e-123 Identities = 131/489 (26%), Positives = 232/489 (47%), Gaps = 32/489 (6%) Query: 1 MSSIDVLIVDDEEDIRNIIAAILKDEGFNSKVAANSTQALKILAEKPVSAVILDIWLQGS 60 M+ +L+ DD+ IR ++ L G++ ++ +N+ + +A V+ D+ + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD- 59 Query: 61 EIDGLGILEIIKKRYPLMPVIIISGHGTIETAVNAIKMGAYDYIEKPFNNDKLVILLKRA 120 + +L IKK P +PV+++S T TA+ A + GAYDY+ KPF+ +L+ ++ RA Sbjct: 60 -ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 121 CEVTKLKRENIDLKSKVIDKTELVGGCSVTLKYKMEIEKAASSSSRIMIQGKVGSGKELA 180 K + L+ D LVG + + + + + +MI G+ G+GKEL Sbjct: 119 LAEPKRRPSK--LEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELV 176 Query: 181 ARLIHKQSKRVNNPFIIFSPTCMTTEKIDQELFGESEK---QENNNKRPTILEFANNGTL 237 AR +H KR N PF+ + + + I+ ELFG EK + E A GTL Sbjct: 177 ARALHDYGKRRNGPFVAINMAAIPRDLIESELFG-HEKGAFTGAQTRSTGRFEQAEGGTL 235 Query: 238 YIDEVSNIPIPIQVKLLKFLKNQTITKPCGDS--IKVDIKIITGTSKNIQDEVNNGKFLE 295 ++DE+ ++P+ Q +LL+ L+ T G I+ D++I+ T+K+++ +N G F E Sbjct: 236 FLDEIGDMPMDAQTRLLRVLQQGEYT-TVGGRTPIRSDVRIVAATNKDLKQSINQGLFRE 294 Query: 296 ELYYRLNVFSLKVPSLYERKEDIPLLIKYFVKQLSKFSGLKERPFADDTIAALQSYEWPG 355 +LYYRLNV L++P L +R EDIP L+++FV+Q K GL + F + + ++++ WPG Sbjct: 295 DLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEK-EGLDVKRFDQEALELMKAHPWPG 353 Query: 356 NIRQLRNVVEWTLIMNP--------------------LTTGNNEIIKPYMIPAEILANSA 395 N+R+L N+V + P I + N Sbjct: 354 NVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMR 413 Query: 396 NLTKLEDSVDMLSMPLREAREVFERQYLSAQMSRFNNNISKTSSFVGMERSALHRKLKLL 455 S E + A ++ N K + +G+ R+ L +K++ L Sbjct: 414 QYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473 Query: 456 SLHIPPANK 464 + + +++ Sbjct: 474 GVSVYRSSR 482
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 31.5 bits (71), Expect = 0.006 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Query: 85 EILDLRNDNNNLLGYVVKNSDFKKILLSKITNHPLVTLIDNYKYQEVISHHNYSVIKF-D 143 E L L N+NN + VV+N+D K + I N +V +NYKY E + N + K + Sbjct: 760 ERLALYNNNNRMDICVVRNTDDIKACGTAIGNQSMVNNPENYKYLEGKAWKNIGISKTAN 819 Query: 144 NEQIKCNLL 152 +I + L Sbjct: 820 GSKISVHYL 828
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.8 bits (67), Expect = 0.022 Identities = 31/159 (19%), Positives = 57/159 (35%), Gaps = 19/159 (11%) Query: 41 VLLNELLFPKADTQTAAIYSAAAFCSTFVFRTFVALLFGWIGDKYGRKSTVIITTLFMAC 100 LL +L+ D A + A + G + D++GR+ ++++ A Sbjct: 30 GLLRDLV-HSNDVTAHYGILLALYALMQFA---CAPVLGALSDRFGRRPVLLVSLAGAAV 85 Query: 101 FCAFMAGLPTYVQIGVTATWIVTICRIIQGMSSLCEIIGAELY--LTETINPPKQYPVVS 158 A MA P W++ I RI+ G++ + +T+ + + +S Sbjct: 86 DYAIMATAPFL--------WVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMS 137 Query: 159 LMFSCAVLGGVAALGLESIIVHYGFSWRITFFIGTFIAI 197 F ++ G GL GFS FF + Sbjct: 138 ACFGFGMVAGPVLGGLMG-----GFSPHAPFFAAAALNG 171
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 66.4 bits (162), Expect = 2e-13 Identities = 44/134 (32%), Positives = 63/134 (47%), Gaps = 19/134 (14%) Query: 338 VMGHVDHGKTSLLDALKSTDIAAGEIG------------------GITQHIGAYRVTLAD 379 V+ HVD GKT+L ++L A E+G GIT G + Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 380 GRAITFIDTPGHEAFSEMRSRGTKVTDIAIIVVAADDGIKTQTVEAINHAKVAGVPIIIA 439 + + IDTPGH F R V D AI++++A DG++ QT + + G+P I Sbjct: 68 TK-VNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFF 126 Query: 440 INKIDKPNIDIERV 453 INKID+ ID+ V Sbjct: 127 INKIDQNGIDLSTV 140
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.1 bits (75), Expect = 0.002 Identities = 21/58 (36%), Positives = 31/58 (53%) Query: 70 IGEFNRVLGGGLVLGAAILIGGDPGIGKSTLLLQLAASNFASKVHCLYITGEESLNQI 127 +G RV+ G ++++ G GIGKSTL+ L +F S H TG++S QI Sbjct: 582 MGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQI 639
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 31.3 bits (71), Expect = 0.021 Identities = 16/72 (22%), Positives = 27/72 (37%), Gaps = 4/72 (5%) Query: 768 KKFLVGVAIVAGLALAAVPFVAMPMLLVTGTALTTKAIILGASILAGVAVAAGTYKFIQK 827 L + L L + +P + + G + G SIL V V T K I+ Sbjct: 368 SYVLNRITWPGSLYLGLI--ALVPTMALVGFGASQNFPFGGTSILIIVGVGLETVKQIES 425 Query: 828 PLRNIQKSFQNL 839 L Q++++ Sbjct: 426 QL--QQRNYEGF 435
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.4 bits (71), Expect = 0.008 Identities = 29/130 (22%), Positives = 48/130 (36%), Gaps = 5/130 (3%) Query: 283 IGGLVGGVIMKHKNILNSILLFGIIHALGHIVFIFLEINGKSSLLLFITIGIESITGGMT 342 IG V G + I +L II+ G ++ LL + I+ Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFV---GHSFFSLLIMARFIQGAGAAAF 120 Query: 343 MTTYIAFISSLCQGKFRATQYSFLSSMMGISRSIFPIISGYIVVNFGWQNFFLF--TTII 400 + ++ + R + + S++ + + P I G I W L TII Sbjct: 121 PALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITII 180 Query: 401 TIPSLLILLK 410 T+P L+ LLK Sbjct: 181 TVPFLMKLLK 190
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 52.7 bits (126), Expect = 2e-10 Identities = 66/262 (25%), Positives = 100/262 (38%), Gaps = 17/262 (6%) Query: 1 MTTGLLHGKKGLITGIANNMSISWAIAQLAKKHEAELWFTYQSEVLEKRVKPLAEEIGCN 60 M + GK ITG A + + A LA + Y E LEK V L E Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVART-LASQGAHIAAVDYNPEKLEKVVSSLKAEARHA 59 Query: 61 FVSKLDVTNPKSISNLFDDIKEKWGSFDFLLHGMAFADKNALNGRYVDTSLENFHNSLHI 120 DV + +I + I+ + G D L++ ++ S E + + + Sbjct: 60 EAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIH----SLSDEEWEATFSV 115 Query: 121 SCYSLLELSRAAEPLMDD--GGSIVTLTYYGAEKVIPNYNIMGISKAALEASVKYLANDM 178 + + SR+ M D GSIVT+ A + SKAA K L ++ Sbjct: 116 NSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 179 GENNIRVNAISAGPIKT-----LASSAIGNFSTMLKSHAAT----TPLKRNTTQEDVGGA 229 E NIR N +S G +T L + G ++K T PLK+ D+ A Sbjct: 176 AEYNIRCNIVSPGSTETDMQWSLWADENGA-EQVIKGSLETFKTGIPLKKLAKPSDIADA 234 Query: 230 AIYLFSNLSKGVTGEIHYVDCG 251 ++L S + +T VD G Sbjct: 235 VLFLVSGQAGHITMHNLCVDGG 256
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.7 bits (77), Expect = 0.001 Identities = 36/188 (19%), Positives = 83/188 (44%), Gaps = 8/188 (4%) Query: 270 LLLIILFVFLYKAADSIPMAMSSP-LFLDLSFTTHEIAIIYKAYGLLIMIIGGALGGILS 328 +L+ + + + + + + +S P + D + + A+ +L IG A+ G LS Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAF-MLTFSIGTAVYGKLS 73 Query: 329 AKIGIFNSVLIGGVIQLLSPLMFMILATIGYDIRTFII-TVTVQNFCAGFAGTIISIYFA 387 ++GI +L G +I ++ +G+ + +I +Q A ++ + A Sbjct: 74 DQLGIKRLLLFGIIINCFGS----VIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVA 129 Query: 388 SLCNSEFVATQYSIIASFSSLSRILLASLGGICAKYLTWPVFFLGNTLFSMLFIPIFYKI 447 E + +I S ++ + ++GG+ A Y+ W L + +++ +P K+ Sbjct: 130 RYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMI-TIITVPFLMKL 188 Query: 448 YRKKLVIK 455 +K++ IK Sbjct: 189 LKKEVRIK 196
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 30.3 bits (68), Expect = 0.041 Identities = 15/87 (17%), Positives = 34/87 (39%), Gaps = 5/87 (5%) Query: 129 DSTKVNIKNFNSLINSLSNKLITDFENNYLDSAFQKLENITNNILKDLNEFGA--EKLGI 186 D ++I++ + NS +++ + + Y F +NI++D++ + Sbjct: 807 DFKFLDIQSIKNFFNSQVEQVMKEILSPYQLLLFASKGP-NSNIIEDISGKNTLIQYTES 865 Query: 187 IFENDNVFSNPLFLY--NRIANLNNNY 211 I V L+L N +N + Sbjct: 866 IELVYGVNGESLYLKSPNETIKFSNKF 892
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.7 bits (67), Expect = 0.042 Identities = 9/84 (10%), Positives = 30/84 (35%), Gaps = 7/84 (8%) Query: 555 YVNLEGRPQIAEKIVSPVG------DAKEDIAIIKELACHLKIDIGMNNLQAVRTKLAEE 608 + + + + ++ A ++ + L +LK++ GMN L ++ Sbjct: 82 FFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTV 141 Query: 609 YKVFASIGKI-IENKFTQFRSKDK 631 ++ ++ + + F + Sbjct: 142 WQQLRAMANVGEMTLMSHFAEAEH 165
>SOPEPROTEIN#Salmonella type III secretion SopE effector protein signature. Length = 239 Score = 32.0 bits (72), Expect = 0.007 Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 31/141 (21%) Query: 46 PSVTRIYSRDGKLMEEYAFERRVFV-PINSVPSSLIESFIAAEDKNFYNHPGVDLLGIIR 104 P RI ++ L++E + E+ I +V + IE ++ F +H + Sbjct: 7 PQNFRIQKQETTLLKEKSTEKNSLAKSILAVKNHFIELRSKLSER-FISHKNTE------ 59 Query: 105 AAFLNISNYLHHRR---MEGASTITQQVVKNFLLTNKVSLD------------RKIKEAI 149 S+ H R EG + +T +VVK+F+L +D + +EAI Sbjct: 60 ------SSATHFHRGSASEGRAVLTNKVVKDFMLQTLNDIDIRGSASKDPAYASQTREAI 113 Query: 150 LSYMISRVLTKDQILELYLNQ 170 LS + S+ KDQ L +++ Sbjct: 114 LSAVYSK--NKDQCCNLLISK 132
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.0 bits (72), Expect = 0.040 Identities = 69/369 (18%), Positives = 118/369 (31%), Gaps = 48/369 (13%) Query: 46 NNNNAAFSDNIGANNWHGITQAGADNAQGVAGPQDNYAFTFGGDHIITADVAGRIIQAIN 105 + AF+ ++G + D ++ F F G D+ G + + Sbjct: 482 GSGQHAFA-SVGIVSGRSTLVLNDDKQVD----PNSIYFGFRGG---RLDLNGNSLTFDH 533 Query: 106 VAGTNPGGLNINHNTNVGSIIT-DGNLLPVTINDNQNLTLTGTNAVDIQHGFNANANIYT 164 + + G +NHN S IT G L I D +T +A D + + Sbjct: 534 IRNIDDGARLVNHNMTNASNITITGESL---ITDPNTITPYNIDAPDEDNPYAFRRI--- 587 Query: 165 GLGNITLGGANAQLTIHSNMPALIILTGNINGGGIITANTDTTINGII--GNANPLAKIS 222 QL ++ L + + N+ + + G + AK + Sbjct: 588 --------KDGGQLYLNLENYTYYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRN 639 Query: 223 VGATTLS---------LGGNIVKANAINLTDNVSELTFTNPVVVTGAIDNTGNAN--NGV 271 V + G K N NL + N ++TG + G+ G Sbjct: 640 VMNHINNERMNGFNGYFGEEEGKNNG-NLNVTFKGKSEQNRFLLTGGTNLNGDLTVEKGT 698 Query: 272 VAFNDASTV----TGSIGNTAALAKLSVGAGLVQV---QGGVVKANAINLTDNASELTFA 324 + + T I +T + +V KA +N+T NAS + Sbjct: 699 LFLSGRPTPHARDIAGISSTKKDPHFAENNEVVVEDDWINRNFKATTMNVTGNASLYSGR 758 Query: 325 NPVIVTGAIDNTGNANNGVVTFNGDSTVTGSIG---NTAALAKLSVGAGLEVQGDVVKAN 381 N +T I + A + GD+ S T KLS A ++ N Sbjct: 759 NVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTDKLSDKALNSFNPTNLRGN 818 Query: 382 AINLTNNAS 390 +NLT +A+ Sbjct: 819 -VNLTESAN 826
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 28.0 bits (62), Expect = 0.041 Identities = 12/36 (33%), Positives = 15/36 (41%), Gaps = 1/36 (2%) Query: 130 YVDFVDLSMFKVFAGAGVGL-AMVKETITGKDVSTN 164 Y D V F ++ G G GL + I KDV Sbjct: 445 YADLVTTESFSIYGGVGAGLGSYTYAKIDNKDVKGY 480
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 45.3 bits (107), Expect = 7e-08 Identities = 36/198 (18%), Positives = 62/198 (31%), Gaps = 23/198 (11%) Query: 1 MKKLLLIAATSATMLSSTLSFADGMDNEWYLRIGAGAAMFNKEKDEATSVKLKSNMTVSV 60 MKK IA A +T++ A DN WY G + ++ + N + Sbjct: 1 MKKTA-IAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHEN-QLGA 58 Query: 61 DLGIGYYFSKNFRTDLTLGTIIGGKLKKSGTATNVPFSGTNVSVSYKPTITRLLINGYVD 120 GY + + +G G++ G+ N + V ++ K Sbjct: 59 GAFGGYQVNPYVGFE--MGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPIT------- 109 Query: 121 LTNFNIFDVFAGAGVGPALVKEKITYNGITGLASTTKNRTNISYKLTLGTSAQIADDVKV 180 + D++ G K G + T +S G I ++ Sbjct: 110 ----DDLDIYTRLGGMVWRADTKSNVYG-------KNHDTGVSPVFAGGVEYAITPEIAT 158 Query: 181 ELAYSWIND-GKAKSKNV 197 L Y W N+ G A + Sbjct: 159 RLEYQWTNNIGDAHTIGT 176
>PF07132#Harpin protein (HrpN) Length = 356 Score = 30.8 bits (69), Expect = 0.002 Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Query: 11 ALVAFMLQACTGSGGMNK--QGSGTLIGGTAGALLGSQFGKGKGQLIGVGAGALLGAILG 68 + M GG+ G G+ +GG G LLG G G G +G G G+ LG LG Sbjct: 54 IMTTMMFMGSMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLGSGLGSALGGGLG 113 Query: 69 NQIGAGMDEQD 79 +GAGM+ + Sbjct: 114 GALGAGMNAMN 124
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 372 bits (956), Expect = e-127 Identities = 103/440 (23%), Positives = 195/440 (44%), Gaps = 19/440 (4%) Query: 78 QTARSPILFGIYVIIFLVLIGGLWAALAPLDSGAVAIGIVIPSTNKKIIQHHEGGIINNI 137 +R P L +++ FLV I + + L ++ A A G + S K I+ E I+ I Sbjct: 52 PVSRRPRLVAYFIMGFLV-IAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 138 YVKQGDKVKEGDKLIELEETRIKSEHENILGQYRHFLATENRL-----IAERDNLEQIEF 192 VK+G+ V++GD L++L +++ + R E + L +++ Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKL 170 Query: 193 SDFL-MQDINLPEVAKIIHTQENLFRSRKEIYNSEKDALYQRIAQLEKKIEGLEAKKVAA 251 D Q+++ EV ++ L + + + ++K + + + + A+ Sbjct: 171 PDEPYFQNVSEEEVLRLTS----LIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRY 226 Query: 252 TKTTEVYQDRLKALRTLKEKGFVQKAALLDQEAKVAASKSEIATTEAEIAGTRHTITESQ 311 + V + RL +L K + K A+L+QE K + +E+ ++++ I ++ Sbjct: 227 ENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAK 286 Query: 312 ISIINLQNKYTEKTLTELRDAQVQTASLKEKYNALTDSLNRVIIRSPVDGVVNNLKYHTI 371 + + + L +LR L + + +IR+PV V LK HT Sbjct: 287 EEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTE 346 Query: 372 GGVIGHGQTIMEISPINDPLIIEAKVSQKNIDSVHEGLVAKIRFSAFKSRTTPTFTGKVV 431 GGV+ +T+M I P +D L + A V K+I ++ G A I+ AF GKV Sbjct: 347 GGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVK 406 Query: 432 SISPDIVQDERQHPGQQQDNYYVARIEIDMDKFNKVAKVKNLALHPGMQAEVQIVTGTRT 491 +I+ D ++D+R V + I +++ KN+ L GM +I TG R+ Sbjct: 407 NINLDAIEDQRLGL--------VFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRS 458 Query: 492 LLRYLLDPVTDTAFKAFREK 511 ++ YLL P+ ++ ++ RE+ Sbjct: 459 VISYLLSPLEESVTESLRER 478
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.9 bits (70), Expect = 0.009 Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 14/92 (15%) Query: 42 LLNNLFFPEYDPFTFSLLTAFSFCSTYLLRPIGALIFGYIGDHFGRKIVVVLTTLLMAIT 101 LL +L + +L A + P+ G + D FGR+ V++++ Sbjct: 31 LLRDLVHSNDVTAHYGILLALYALMQFACAPVL----GALSDRFGRRPVLLVS------- 79 Query: 102 CVIIGSMLTYAQIGITAS-WVLTICRIIQGMS 132 + G+ + YA + WVL I RI+ G++ Sbjct: 80 --LAGAAVDYAIMATAPFLWVLYIGRIVAGIT 109
>PF06580#Sensor histidine kinase Length = 349 Score = 27.9 bits (62), Expect = 0.040 Identities = 14/54 (25%), Positives = 29/54 (53%), Gaps = 3/54 (5%) Query: 155 LFDRIHNLQTLGAQSPEKAHKIIK---ETLKSFLVLSEMLEISLVSELMYAECY 205 +F+ ++N++ L + P KA +++ E ++ L S ++SL EL + Y Sbjct: 175 MFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSY 228
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 48.5 bits (115), Expect = 2e-08 Identities = 28/130 (21%), Positives = 60/130 (46%), Gaps = 6/130 (4%) Query: 74 EDAKKSEQSKPKAEPQDSPKEEKAQEIETKTLEETPKVEENKP--IEDPKSEEVKELLSE 131 ++ +E ++ + E+ Q+ T + +E K + ++ EV + SE Sbjct: 1032 TPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSE 1091 Query: 132 KKE----EIKEEKSKKEEKKQAEEKKKSKKKPKEVKKKEPKTDELDSLLKNLEQSSEGDN 187 KE E KE + ++E+K E +K+++ PK + PK ++ +++ E + E D Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 188 VKSNKHKRSK 197 + K +S+ Sbjct: 1152 TVNIKEPQSQ 1161 Score = 44.7 bits (105), Expect = 4e-07 Identities = 40/174 (22%), Positives = 73/174 (41%), Gaps = 18/174 (10%) Query: 39 EKLPEEQTITFEILPVSDKSNIITQTKQKEAHIENEDAKKSEQSKPKAEPQDSPKEEKAQ 98 E+ E T + KSN+ T+ E + K++ Q+ E KEEKA+ Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKET-QTTETKETATVEKEEKAK 1113 Query: 99 EIETKTLEETPKVEENKPIEDPKSEEVKELLSEKKEEIKEEKSKK---EEKKQAEEKKKS 155 ET+ +E PKV + +SE V+ +E K+ + A+ ++ + Sbjct: 1114 V-ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPA 1172 Query: 156 KKKPKEVKKKEPK---TDELDSLLKNLEQS----------SEGDNVKSNKHKRS 196 K+ V++ + + +S+++N E + SE N N+H+RS Sbjct: 1173 KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRS 1226
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 35.3 bits (81), Expect = 3e-04 Identities = 15/51 (29%), Positives = 20/51 (39%) Query: 85 PEIPKLPDPPKLETPIPPPPPPPVVKMPPVLPPTTPVEEKKDKTLPLPPIS 135 PE P+P P PP P V++ P P P KK + P + Sbjct: 65 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVK 115 Score = 31.5 bits (71), Expect = 0.005 Identities = 14/51 (27%), Positives = 18/51 (35%), Gaps = 1/51 (1%) Query: 76 PVTDVEDNIPEIPKLPDPPKLETPIPPPPPPPVVKMPPVLPPTTPVEEKKD 126 PV + E IP+ P + P P P P K P P + K Sbjct: 67 PVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPK-PVKKVQEQPKRDVKP 116 Score = 29.6 bits (66), Expect = 0.025 Identities = 15/67 (22%), Positives = 22/67 (32%), Gaps = 3/67 (4%) Query: 75 KPVTDVEDNIPEIPKLPDPPKLETPIPPPPPPPVVKMPPVLPPTTPVEEKKDKTLPLPPI 134 P V + PE +P+PP P P K P P V+E+ + + Sbjct: 63 PPPEPVVEPEPEPEPIPEPP---KEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVES 119 Query: 135 SLPSTSG 141 S Sbjct: 120 RPASPFE 126
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 31.7 bits (71), Expect = 0.001 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 2/42 (4%) Query: 74 IEFAKNEEIKNIILGDSYAWKITPLANRLFIKPLEKDIRTNM 115 I+ K+E I I G + W I P +N +FI+P K +++N+ Sbjct: 67 IQLEKDETISYITTGFNKGWSIVPNSNHIFIQP--KSVKSNL 106
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 179 bits (455), Expect = 2e-58 Identities = 39/209 (18%), Positives = 83/209 (39%), Gaps = 4/209 (1%) Query: 35 TQNWYEERSDKLIVQRNLLIILIIILTIFMVISTLVIAFVVKSKQFDPFVIQLNSNTGRA 94 +W ++ + L ++ + + +A + K +P+VI ++ NTG A Sbjct: 17 AASWERDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEA 76 Query: 95 SVVEPMSSP-VLTADESLTRYFIKKYITARETYNPVDFTTLARTTIRLLSTSSVYYNYLS 153 S+ + +T DE++ +YF+ Y+ RE + + ++S + Sbjct: 77 SIAAKLHGDATITYDEAVRKYFLATYVRYREGWIAAAR-EEYFDAVMVMSARPEQDRWSR 135 Query: 154 YIR-NKDFDPILKYKEDNTTFLVIKSWSKIAADKYIVRFSVNETSGNQL-VYNKIAVVSY 211 + + + P F+ IK S + + V F+ +G+ + +A + Y Sbjct: 136 FYKTDNPQSPQNILANRTDVFVEIKRVSFLGGNVAQVYFTKESVTGSNSTKTDAVATIKY 195 Query: 212 AYVPMQLTDSELDINPVGFQVNGYRVDDD 240 + + NP+G+QV YR D + Sbjct: 196 KVDGTPSKEVDRFKNPLGYQVESYRADVE 224
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 180 bits (457), Expect = 5e-59 Identities = 39/211 (18%), Positives = 68/211 (32%), Gaps = 2/211 (0%) Query: 13 KSGEYFIDARQWYNFKYILPLSHRSLLLLICTVFTLLLILICININILLPINEKVSYLIK 72 + YF +A W K + L ++ V L + + L P+ Y+I Sbjct: 9 ELKAYFEEAASWERDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVIT 68 Query: 73 DDAE-QQATITNTKHSSLVNPYI-AVANIMLQNYVKQREEYNYDTLKEQFIFIKNTSTSI 130 D +A+I H Y AV L YV+ RE + +E F + S Sbjct: 69 VDRNTGEASIAAKLHGDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARP 128 Query: 131 VYMQFANLMNIDNPLSPVIRYQKLYKRSINILSINNINDNKAVVTFESLAKNSTGEILEN 190 +++ DNP SP + I ++ + N A V F + + + Sbjct: 129 EQDRWSRFYKTDNPQSPQNILANRTDVFVEIKRVSFLGGNVAQVYFTKESVTGSNSTKTD 188 Query: 191 MLWESRIGFIMDAIGINISPDTAFNFTITSY 221 + + + + SY Sbjct: 189 AVATIKYKVDGTPSKEVDRFKNPLGYQVESY 219
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 40.5 bits (94), Expect = 4e-06 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 14/102 (13%) Query: 156 HPEKYNFNYYISG---SEEIAPIKIFDDGEFTYLQFRDKNAEISGIFAVDDSLRESLVNY 212 +P N+NYY + S+ I P +IFDDG FTY F++ + IF V + S+ + Sbjct: 395 NPVPRNYNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQ-PAIFVVQPDGKLSMTD- 452 Query: 213 HLAQDNPNMVIL-------EQVFPKLAIRKGKKVTCVFNQSF 247 A +PNM ++ K + K K + V N+ + Sbjct: 453 --AAIDPNMTNSGLRWYRVNEIAEKFKLIKDKALVTVINKGY 492 Score = 34.0 bits (77), Expect = 4e-04 Identities = 15/33 (45%), Positives = 20/33 (60%) Query: 55 IELARDEEIVSISMGDTTSWQIVPAGHRIFIKP 87 I+L +DE I I+ G W IVP + IFI+P Sbjct: 67 IQLEKDETISYITTGFNKGWSIVPNSNHIFIQP 99
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 67.0 bits (163), Expect = 3e-16 Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 2/130 (1%) Query: 1 MKDKVTVITGSTSGIGLKIAKHFAKLESKIVINGFTKEDEVAKISAELKELGASSVFYQG 60 ++ K+ ITG+ GIG +A+ A + I + E +S+ E + F Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF--P 63 Query: 61 INLEKPDEIRSMFEKIIKEFGKIDILVNNAGIQHVAPIDEFPEDKWEQILRIDLIASFYT 120 ++ I + +I +E G IDILVN AG+ I +++WE ++ F Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 121 TKYVIPIMKK 130 ++ V M Sbjct: 124 SRSVSKYMMD 133
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 34.6 bits (79), Expect = 2e-05 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 4/87 (4%) Query: 1 MAENNITVNAICPGYVNIPLVKN-QIADTAKARNISGESALQDVILKSHATKKFVEADEI 59 +AE NI N + PG + + + + I G + KK + +I Sbjct: 175 LAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGI---PLKKLAKPSDI 231 Query: 60 ANLVIFLCDEKASSITGSGLLIDGGWT 86 A+ V+FL +A IT L +DGG T Sbjct: 232 ADAVLFLVSGQAGHITMHNLCVDGGAT 258
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 25.9 bits (56), Expect = 0.034 Identities = 20/89 (22%), Positives = 34/89 (38%), Gaps = 13/89 (14%) Query: 2 IFIEGGSQVGKTTLAKNLNLYLSLVVFLSLIFQPLQDGLSQSMLIEPKTSSNQGLNP--- 58 ++ E G + ++K+ +L FL+LI D S +L K LN Sbjct: 169 VYYEIGKGISLDIISKDKSLDPE---FLNLIKSLSDDSDSSDLLFSQKFKEKLELNNKSI 225 Query: 59 -------NLKYFQELLNCPFAFQVTPNMK 80 NL FQ + F++ P+ + Sbjct: 226 DINFIKENLTEFQHAFSLAFSYYFAPDHR 254
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.9 bits (75), Expect = 0.002 Identities = 62/294 (21%), Positives = 107/294 (36%), Gaps = 28/294 (9%) Query: 66 LFGYIGDRYGRRTALIISMLGMTIPTFIMGLIPSYTSIGIYAPITLVIMRLIQGLCISGE 125 + G + DR+GRR L++S+ G + IM P L I R++ G+ Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW--------VLYIGRIVAGIT-GAT 112 Query: 126 GTGAAIFIL----EHRQNLKPGFTAGLVHGSNIAGTLVATFIGIIIERYFSHIDFAWRFA 181 G A +I + GF + +AG ++ +G + H F A Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG----GFSPHAPFF--AA 166 Query: 182 FLLGGFMGLVGFYLRLRVSETPIFKMLEKKKQVLKAPFSNVIKTAWRSMFLTMCIGAIAS 241 L G L G +L L S + L ++ A F + M + I Sbjct: 167 AALNGLNFLTGCFL-LPESHKGERRPLRREALNPLASFR--WARGMTVVAALMAVFFIMQ 223 Query: 242 SVMYLVKTYINVFYNNVMHL-GNTIALSYLAYSSFIAMIAMPLAGATTDIIGKFKTAMFV 300 V + +F + H TI +S A+ ++ + G +G+ + A+ + Sbjct: 224 LVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGE-RRALML 282 Query: 301 GVAILILILPTMLLMSAEEMWQQFIALTILGMLAGSIAGTAYIFVISLFTAEQR 354 G+ +LL A W F + +L +G I A ++S E+R Sbjct: 283 GMIADGTGY--ILLAFATRGWMAFPIMVLLA--SGGIGMPALQAMLSRQVDEER 332