>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.7 bits (233), Expect = 2e-24 Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 1/124 (0%) Query: 4 KVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGME 63 ++V DD+ I +L L + GYDV + I + D+V+ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 VCREVRKKYE-MPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYS 122 + ++K +P+++++A+++ + + E GA DY+ KPF ELI + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 123 QPAQ 126 +P++ Sbjct: 125 RPSK 128
>PF01206#SirA family protein Length = 76 Score = 65.6 bits (160), Expect = 6e-16 Identities = 24/70 (34%), Positives = 39/70 (55%) Query: 118 KQFDFRGLQCPGPIVNISKEINNISTGEQIEVTVTDPGFNSDIKSWAKQTGNTLVNLTEE 177 + D GL CP PI+ K + ++ GE + V TDPG D +S++KQTG+ L+ EE Sbjct: 6 QSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKEE 65 Query: 178 ANVINAIIQK 187 + +++ Sbjct: 66 DGTYHFRLKR 75
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.3 bits (71), Expect = 0.011 Identities = 12/74 (16%), Positives = 27/74 (36%), Gaps = 7/74 (9%) Query: 264 VVSENDNIIQNRSRTTKVIPYGKQEFLDEVFIDES-----DYDRLVQLLRRKRNVILQGP 318 ++ + R + Q+ + + S Y L +L++ +++ G Sbjct: 111 LIGIIGRALAEPKRRPSKLEDDSQDGMP--LVGRSAAMQEIYRVLARLMQTDLTLMITGE 168 Query: 319 PGVGKTFLAKRLAY 332 G GK +A+ L Sbjct: 169 SGTGKELVARALHD 182
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 70.4 bits (172), Expect = 7e-16 Identities = 47/191 (24%), Positives = 78/191 (40%), Gaps = 38/191 (19%) Query: 53 PKRVVTLYQGATDVAVSLGVKPVGAVES-----WTQKPKFEYIKNDLKDTKI-VGQEPAP 106 P R+V L ++ ++LG+ P G ++ W +P L D+ I VG P Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPP-------LPDSVIDVGLRTEP 87 Query: 107 NLEEISKLKPDLIVASKVRNEKVYDQLSKIAPTVSTDTVFKFKD----------TTKLMG 156 NLE ++++KP +V S + L++IAP F F D + M Sbjct: 88 NLELLTEMKPSFMVWS-AGYGPSPEMLARIAPGR----GFNFSDGKQPLAMARKSLTEMA 142 Query: 157 KALGKEKEAEDLLKKYDDKVAAFQKDAKAKY--KDAWPLKASVVNF-RADHTRIYA-GGY 212 L + AE L +Y+D F + K ++ + A PL + H ++ Sbjct: 143 DLLNLQSAAETHLAQYED----FIRSMKPRFVKRGARPL--LLTTLIDPRHMLVFGPNSL 196 Query: 213 AGEILNDLGFK 223 EIL++ G Sbjct: 197 FQEILDEYGIP 207
>SYCECHAPRONE#Gram-negative bacterial type III secretion SycE chaperone signature. Length = 130 Score = 31.2 bits (70), Expect = 0.002 Identities = 14/33 (42%), Positives = 16/33 (48%), Gaps = 1/33 (3%) Query: 25 VDALTEALTAHAHNDFVQ-PLKPYLRQDPENGH 56 +D E T +HN F Q LKP L D GH Sbjct: 54 LDNNDEKETLLSHNIFSQDILKPILSWDEVGGH 86
>PF04183#IucA / IucC family Length = 580 Score = 318 bits (816), Expect = e-103 Identities = 121/527 (22%), Positives = 209/527 (39%), Gaps = 46/527 (8%) Query: 79 RASKQPLTAAEFWQTIANMNCDLSHEWEVARVEEGLTTAATQLAKQLSELDLASHPFV-- 136 R + +P+ A + + +S +++ T L + L++ + Sbjct: 66 RCADEPVLAQTLLMQLKQVL-SMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINL 124 Query: 137 -MSEQFASLKDRPFHPLAKEKRGLREADYQVYQAELNQSFPLMVAAVKKTQMIHGDTANI 195 L P K +RG + + Y E +F L AVK+ MI + Sbjct: 125 NADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEM 184 Query: 196 DELESLTAPIKEQA----TDMLHDQGLSIDDYVLFPVHPWQYQHILPNVFAKEIREKLVV 251 D + LTA + Q + + + GL +++ PVHPWQ+Q + F + E +V Sbjct: 185 DIHQLLTAAMDPQEFARFSQVWQENGLD-HNWLPLPVHPWQWQQKIATDFIADFAEGRMV 243 Query: 252 PLPLKFGD-YLSASSMRSLINIAAPYN-HVKVPFAMQSLGALRLTPTRYMKNGEQAERLL 309 L +FGD +L+ S+R+L N + +K+P + + R P RY+ G A R L Sbjct: 244 SLG-EFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWL 302 Query: 310 RQLIEKDAMLAKY-VTVCDETA-------WWSYMGQDNDIFKDQLGHLTVQLRKYPEVLA 361 +Q+ DA L + + E A ++ + + +++ LG V R+ P Sbjct: 303 QQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLG---VIWRENPCRWL 359 Query: 362 KNDTQQLVSMAALAANDRTLYQMICGKDNISKKDVMTLFEDIAQVFLKVTLSFM-QYGAL 420 K D + V MA L D + + S D T + +V + + +YG Sbjct: 360 KPD-ESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVA 418 Query: 421 PELHGQNILLSFEDGRVQKCVLRD-HDTVRIYKPWLTAHQLSLPKYV--VREDTPNTLIN 477 HGQNI L+ ++G Q+ +L+D +R+ K SLP+ V V + Sbjct: 419 LIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMD-SLPQEVRDVTSRLSADYLI 477 Query: 478 EDLETFFAYFQTLAVSVNLYAIIDAIQDLFGVSEHELMSLLKQILKNEVATISWVTTDQL 537 DL+T V + I + GV E LL +L + + Q+ Sbjct: 478 HDLQTGHF--------VTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMK-----KHPQM 524 Query: 538 AVRHILFDKQTWPFKQILLP---LLY-QRDSGGGSMPSGLTTVPNPM 580 + R LF +++L L + D G +P+ L + NP+ Sbjct: 525 SERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNPL 571
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 80.3 bits (198), Expect = 1e-18 Identities = 71/372 (19%), Positives = 149/372 (40%), Gaps = 24/372 (6%) Query: 13 ILWLSQFIAIAGLTVLVPLLPIYMASLQNLSVVEIQLWSGIAIAAPAVTTMIASPIWGKL 72 ++ + + G+ +++P+LP + L + ++ GI +A A+ +P+ G L Sbjct: 9 VILSTVALDAVGIGLIMPVLPGLLRDL--VHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 73 GDKISRKWMVLRALLGLAVCLFLMALCTTPLQFVLVRLLQGLFGGVVDASSAFASAEAPA 132 D+ R+ ++L +L G AV +MA + R++ G+ G + A+ + Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDG 126 Query: 133 EDRGKVLGRLQSSVSAGSLVGPLIGGVTASILGFSALLMSIAVITFIVCIFGALKLIETT 192 ++R + G + + G + GP++GG+ A + A + + + G L E+ Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLMGGF-SPHAPFFAAAALNGLNFLTGCFLLPESH 185 Query: 193 HMPKSQTPNINKGIRRSFQCLLCTQQTCRFIIVGVLANFAMYGMLTALSPLASSVNHTAI 252 + SF+ + V A A++ ++ + + +++ Sbjct: 186 KGERRPLRREALNPLASFR--------WARGMTVVAALMAVFFIMQLVGQVPAALWVIFG 237 Query: 253 DDR-----SVIGFLQSAF-WTASILSAPLWGRFNDKSYVKSVYIFATIACGCSAILQGLA 306 +DR + IG +AF S+ A + G + + + IA G IL A Sbjct: 238 EDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFA 297 Query: 307 TNVEFLMAARILQGLTYSAL--IQSVMFVVVNACHQ-QLKGTFVGTTNSMLVIGQIIGSL 363 T +L + +Q+++ V+ Q QL+G+ T+ + I+G L Sbjct: 298 TRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTS----LTSIVGPL 353 Query: 364 SGAAITSYTTPA 375 AI + + Sbjct: 354 LFTAIYAASITT 365
>PF04183#IucA / IucC family Length = 580 Score = 300 bits (770), Expect = 1e-96 Identities = 115/539 (21%), Positives = 212/539 (39%), Gaps = 61/539 (11%) Query: 3 NKELIQHAAYAAIERILNEYFREENLYQVPPQNHQWSIQLSELE-TLTGQFAYWSAMGHH 61 N + + ++L+E E+ + + ++ I L + + W G Sbjct: 2 NHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIW---GW- 57 Query: 62 MYHPEVWLIDGKSKKLTTYKEAIARILQHMAQSADNQTA-VQQHMAQIMSDI--DNSIHR 118 ID ++ + +L + Q A V +HM + + + D + + Sbjct: 58 ------LWIDAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLK 111 Query: 119 TARYLQSNTIDYAEDRYIVSEQSLYLGHPFHPTPKSASGFSEADLEKYAPECHTSFQLHY 178 R L ++ + Q L GHP K G+ + LE+YAPE +F+LH+ Sbjct: 112 ARRGLSASD---LINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHW 168 Query: 179 LAVHQD-------------VLLTRYVEGKEDQVEKVLYQLADIDISEIPKDFILLPIHPY 225 LAV ++ LLT ++ +E ++Q +D +++ LP+HP+ Sbjct: 169 LAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLD-----HNWLPLPVHPW 223 Query: 226 QINVLRQHPQYMQYSEQGLIKDLGVSGDSVYPTSSVRTVF--SKALNIYLKLPIHVKITN 283 Q ++ +G + LG GD S+RT+ S+ + +KLP+ + T+ Sbjct: 224 QWQQK-IATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTS 282 Query: 284 FIRTNDLEQIERTIDAAQVIASVKDE-----------VETPHFKLMFEEGYRALLPNPLG 332 R I A++ + V + P + EGY AL P Sbjct: 283 CYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYR 342 Query: 333 QTVEPEMDLLTNSAMIVREGIPNY-HADKDIHVLASLFETMPDSPTSKLSQVIEQSGLAP 391 EM +I RE + D+ ++A+L E ++ I++SGL Sbjct: 343 YQ---EM-----LGVIWRENPCRWLKPDESPVLMATLMECDENN-QPLAGAYIDRSGLDA 393 Query: 392 EAWLECYLDRTLLPILKLFSNTGISLEAHVQNTLIELKDGIPEVCYVRDLEG-ICLSRTI 450 E WL ++P+ L G++L AH QN + +K+G+P+ ++D +G + L + Sbjct: 394 ETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEE 453 Query: 451 ATEKQLVPNVVAASSPVVYAHDEAWHRLKYYVVVNHLGHLVSTIGKATRNEVVLWKLVA 509 E +P V + + A D H L+ V L + + + E ++L+A Sbjct: 454 FPEMDSLPQEVRDVTSRLSA-DYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQLLA 511
>PF04183#IucA / IucC family Length = 580 Score = 502 bits (1295), Expect = e-175 Identities = 143/592 (24%), Positives = 257/592 (43%), Gaps = 40/592 (6%) Query: 25 VNQTILNRVKTRVMYQLVSSLIYENIVVYKASYQDGVGYFTIEGNDSEYRFTAEKTHSFD 84 +N + V R++ +++S L YE + + A Q G + I +++RF AE+ + Sbjct: 1 MNHKDWDLVNRRLVAKMLSELEYEQV--FHAESQ-GDDRYCINLPGAQWRFIAERG-IWG 56 Query: 85 RIRITSPIERVVGDEADTTTDYTQLLREVVFTFPKNDEKLEQFIVELLQTELKDTQSMQY 144 + I + R AD LL ++ +D + + + +L T L D Q ++ Sbjct: 57 WLWIDAQTLRC----ADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKA 112 Query: 145 RESNPPATPETFN-DYEFYAMEGHQYHPSYKSRLGFTLSDNLKFGPDFVPNVKLQWLAID 203 R + N D + GH K R G+ ++ P++ +L WLA+ Sbjct: 113 RRGLSASDLINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVK 172 Query: 204 KDKVETTVSRNVVVNEMLRQQVGDKTYEHFVQQIEASGKHVNDVEMIPVHPWQFEHVIQV 263 ++ + + ++++L + + + F Q + +G N + +PVHPWQ++ I Sbjct: 173 REHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWL-PLPVHPWQWQQKIAT 231 Query: 264 DLAEERLNGTVLWLGESDELYHPQQSIRTMSPIDTT-KYYLKVPISITNTSTKRVLAPHT 322 D + G ++ LGE + + QQS+RT++ +K+P++I NTS R + Sbjct: 232 DFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRY 291 Query: 323 IENAAQITDWLKQIQQQDTYLKDE----LKTAFLGEVLGQSYLNTQLSPYKQTQVYGALG 378 I + WL+Q+ D L L G V + Y +PY+ ++ LG Sbjct: 292 IAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEM---LG 348 Query: 379 VIWRENIYHMLIDEEDAIPFNALYASDKDGVPFIENWIKQYG--SEAWTKQFLAVAIRPM 436 VIWREN L +E + L D++ P +I + G +E W Q V + P+ Sbjct: 349 VIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPL 408 Query: 437 IHMLYYHGIAFESHAQNMMLIHENGWPTRIALKDFHDGVRFKREHLSEAASHLTLKPMPE 496 H+L +G+A +H QN+ L + G P R+ LKDF +R +E E S +P+ Sbjct: 409 YHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDS------LPQ 462 Query: 497 AHKKVNSNSFIETDDERLVRDFLH---DAFFFINIAEIILFIEKQYGIDEKLQWKWVKGI 553 + V S RL D+L F+ + I + + G+ E+ ++ + + Sbjct: 463 EVRDVTS---------RLSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQLLAAV 513 Query: 554 IEAYQEAFPELNN-YQHFDLFEPTIQVEKLTTRRL-LSDSELRIHHVTNPLG 603 + Y + P+++ + F LF P I L +L D + + N L Sbjct: 514 LSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLE 565
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 128 bits (323), Expect = 4e-38 Identities = 66/250 (26%), Positives = 113/250 (45%), Gaps = 2/250 (0%) Query: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64 K+A +TG AQGIG +A L G +A VD+N E + L ++ A A ADV + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAGVLWGIQAAH 124 + + + G ++VN AG+ I ++++E+++ + VN GV ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 125 EQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFAP 184 + G I+ S ++ Y S+K A T+ +LA I N +P Sbjct: 129 KYMMD-RRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 185 GIVQTPMMESIAVATAEEAGKPEAWGWEQFTSQIALGRVSQPEDVSNVVSFLAGKDSDYI 244 G +T M S+ + E F + I L ++++P D+++ V FL + +I Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSL-ETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 245 TGQTIIVDGG 254 T + VDGG Sbjct: 247 TMHNLCVDGG 256
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 215 bits (550), Expect = 3e-70 Identities = 80/327 (24%), Positives = 140/327 (42%), Gaps = 33/327 (10%) Query: 6 KVLITGGAGFIGSHLVDDL-QQDYDVYVLDNYRTG-----KRENIKSLADDHVF--ELDI 57 K L+TG AGFIG H+ L + + V +DN K+ ++ LA ++D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 58 REYDAVEQIMKTYQFDYVIHLAALVSVAESVEKPILSQEINVVATLKLLETIKKYNSHIK 117 + + + + + F+ V ++V S+E P + N+ L +LE + I+ Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK--IQ 119 Query: 118 RFIFASSAAVYGDLPDLPKSDQSLI-LPLSPYAIDKYYGERTTLNYCSLYNIPTAVVKFF 176 ++ASS++VYG +P S + P+S YA K E Y LY +P ++FF Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 177 NVFGPRQDPKSQYSGVISKMFDSFEHNKPFTFFGDGLQTRDFVYVYDVVQSVRLIMEH-- 234 V+GP P M K + G RDF Y+ D+ +++ + + Sbjct: 180 TVYGPWGRPDMALFKFTKAML----EGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIP 235 Query: 235 ---------------KDAVGHGYNIGTGTFTNLLEVYRIIGELYGKSVEHDFKEARKGDI 279 A YNIG + L++ + + + G + + + GD+ Sbjct: 236 HADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDV 295 Query: 280 KHSYADISNL-KALGFVPKYTVETGLK 305 + AD L + +GF P+ TV+ G+K Sbjct: 296 LETSADTKALYEVIGFTPETTVKDGVK 322
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.1 bits (73), Expect = 0.004 Identities = 44/238 (18%), Positives = 84/238 (35%), Gaps = 20/238 (8%) Query: 7 TLKVRLISNFLQLIITTAFIPFIALYLTDMLS----QSIVGIYLVGLVVLKFPLSIISGY 62 L V L + L + +P + L D++ + GI L +++F + + G Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 63 LIEIFPKKLLVLIYQATMVIMLVFMGIFGSHQLWQI-IGFCVAYAIFTIVWGLQFPVMDT 121 L + F ++ ++L+ A + M + LW + IG VA + G V Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMAT--APFLWVLYIGRIVAG-----ITGATGAVAGA 118 Query: 122 LIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGYSMLLLFLIAACIFLIVLFILY 181 I D D + + G +LGGLM G+S F AA + + Sbjct: 119 YIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGC 178 Query: 182 IWLPQDRNQVKQSDDKKHASRYQKLQIMNIFRSYKLVLKDRNYMLLISGFSIIMMGEF 239 LP+ ++ ++ + + L+ F + ++G+ Sbjct: 179 FLLPESHKGERRPLRREALNPLASFRWARGMTVVAA--------LMAVFFIMQLVGQV 228
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 55.2 bits (133), Expect = 1e-09 Identities = 55/266 (20%), Positives = 101/266 (37%), Gaps = 55/266 (20%) Query: 2046 KTLLTGATGFLGAYLIEALQGYSHRIYCFIRADNEEIAWYKLMTNLNDYFS----EETVE 2101 K L+TGA GF+G ++ + L H++ + D NLNDY+ + +E Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQV---VGID-----------NLNDYYDVSLKQARLE 47 Query: 2102 MM----LSNIEVIVGDFECMDDVVLPENMDTIIH----AGARTDHFGDDDEFEKVNVQGT 2153 ++ ++ + D E M D+ + + + R + + N+ G Sbjct: 48 LLAQPGFQFHKIDLADREGMTDLFASGHFERVFISPHRLAVR-YSLENPHAYADSNLTGF 106 Query: 2154 VDVIRLAQQHH-ARLIYVSTISV-GTYFDIDTEDVTFSEADVYKGQLLTSPYTRSKFYSE 2211 ++++ + + L+Y S+ SV G + FS D + S Y +K +E Sbjct: 107 LNILEGCRHNKIQHLLYASSSSVYG-----LNRKMPFSTDDSVDHPV--SLYAATKKANE 159 Query: 2212 LKVLEAVKN-GLDGRIVRVGNLTSPYNGRWHM------RNIKTNRFSMVMNDLLQLDCIG 2264 L GL +R + P+ GR M + + + V N Sbjct: 160 LMAHTYSHLYGLPATGLRFFTVYGPW-GRPDMALFKFTKAMLEGKSIDVYNY-------- 210 Query: 2265 VSLAEMPVDFSFVDTTARQIVALAQV 2290 +M DF+++D A I+ L V Sbjct: 211 ---GKMKRDFTYIDDIAEAIIRLQDV 233
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 29.2 bits (65), Expect = 0.009 Identities = 15/57 (26%), Positives = 27/57 (47%), Gaps = 5/57 (8%) Query: 84 GQP-----IYVSLSYSYPYIVCVVDKEPVGIDIEKISQRLDWRTLVTCFSTNEAHQI 135 QP ++ S+S+ + V+ ++ +GIDIEKI + L ++ QI Sbjct: 76 RQPLWPDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATELAPSIIDSDERQI 132
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 34.4 bits (79), Expect = 3e-04 Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 7/84 (8%) Query: 155 INADTLAYFIAASLEAPIYV-LSNIAGVLIN-----DVVIPQLPLADINQYIEHGD-IYG 207 I+ D +A + A I++ L+++ G + + + ++ + ++ +Y E G G Sbjct: 213 IDKDLAGEKLAEEVNADIFMILTDVNGAALYYGTEKEQWLREVKVEELRKYYEEGHFKAG 272 Query: 208 GMIPKVLDAKNAIKNGCPKVIIAS 231 M PKVL A I+ G + IIA Sbjct: 273 SMGPKVLAAIRFIEWGGERAIIAH 296
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 58.1 bits (140), Expect = 1e-12 Identities = 30/99 (30%), Positives = 53/99 (53%) Query: 86 LDKRDDDFVIDKRQFSAFVGTDLDLQLRRRGIDTIVLGGVATHVGVDTTARDAYQLNYDQ 145 L DDD V+ K ++SAF T+L +R+ G D +++ G+ H+G TA +A+ + Sbjct: 112 LAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKA 171 Query: 146 YFVTDMMSAQNETLHQFPIDNVFPLMGQTITTNDLLNIL 184 +FV D ++ + HQ ++ T+ T+ LL+ L Sbjct: 172 FFVGDAVADFSLEKHQMALEYAAGRCAFTVMTDSLLDQL 210
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 37.5 bits (87), Expect = 9e-05 Identities = 53/361 (14%), Positives = 121/361 (33%), Gaps = 40/361 (11%) Query: 30 AFFVVFFVYMAMYLIRNNFKAAQPFLKEEIGLSTLELGYIGL---AFSITYGLGKTLLGY 86 V + + LI P L ++ S + G+ +++ +LG Sbjct: 10 ILSTVALDAVGIGLI----MPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 87 FVDGRNTKRIISFLLILSAITVLIMGFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYST 146 D + ++ L +A+ IM + F V+ + ++ G+ G G + + Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMAT--APFLWVLYIGRIVAGITG----ATGAVAGAY 119 Query: 147 ISRWAPRTKRGRYLGFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGI 206 I+ +R R+ GF + G + H F + + L + Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP----FFAAAALNGLNFL 175 Query: 207 ATLFIGKDDPEELGWNRAEEIWEEPVDKENIDSQGMTKWEIFKKYILGNPVIWILCVSNV 266 F+ + + + P+ +E ++ +W V ++ V + Sbjct: 176 TGCFLLPE---------SHKGERRPLRREALNPLASFRWARGMT-----VVAALMAVFFI 221 Query: 267 FVYIVRIGIDNWAPLYVSEHLHFSKGDAVNTIFYFEI-GALVASLLWGYVSDLLKGRRAI 325 + ++ W ++ + H+ ++ F I +L +++ G V+ L RRA+ Sbjct: 222 MQLVGQVPAALWV-IFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRAL 280 Query: 326 VAIGCMFMITFVVLFYTNATSVMMVNISLFALGALIFGPQLLIGVSLTGFVPKNAISVAN 385 + +++L + + + L A G I P +L + + Sbjct: 281 MLGMIADGTGYILLAFATRGWMAFPIMVLLASGG-IGMP------ALQAMLSRQVDEERQ 333 Query: 386 G 386 G Sbjct: 334 G 334
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.7 bits (207), Expect = 1e-20 Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 12/169 (7%) Query: 3 KVVICDDERIIREGLKQIIPWGDYHFNTIYTAKDGVEALSLIQQHQPELVITDIRMPRKN 62 +++ DD+ IR L Q + Y + + I +LV+TD+ MP +N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY---DVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GVDLLNDI--AHLDCNVIILSSYDDFEYMKAGIQHHVLDYLLKPVDHAQLEVILGRLVRT 120 DLL I A D V+++S+ + F + DYL KP D L ++G + R Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFD---LTELIGIIGRA 118 Query: 121 LLEQQSQNGRSLAPCHDAFQPLLKVEYDDYYVNQIVDQIKQSYQTKVTV 169 L E + + + D Q + + + +I + + QT +T+ Sbjct: 119 LAEPKRR----PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>PF06580#Sensor histidine kinase Length = 349 Score = 147 bits (372), Expect = 6e-42 Identities = 55/226 (24%), Positives = 109/226 (48%), Gaps = 16/226 (7%) Query: 288 YIYDLFESNEQLIHSIEHTERRLRDIQLKEIERQFQPHFLFNTMQTIQYLITLSPKLAQT 347 + + F++ +Q ++ QL ++ Q PHF+FN + I+ LI P A+ Sbjct: 136 FGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKARE 195 Query: 348 VVQQLSQMLRYSLR-TNSHTVELNEELNYIEQYVAIQNIRFDDMIKLHIESSEEARHQTI 406 ++ LS+++RYSLR +N+ V L +EL ++ Y+ + +I+F+D ++ + + + Sbjct: 196 MLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQV 255 Query: 407 GKMMLQPLIENAIKHGRDTESLDITIRLTLARQN--LHVLVCDNGIGMSSSRLQYVRQSL 464 M++Q L+EN IKHG I L + N + + V + G L+ ++S Sbjct: 256 PPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA----LKNTKES- 310 Query: 465 NNDVFDTKHLGLNHLHNKAMIQYGSHARLHIFSKRNQGTLICYKIP 510 GL ++ + + YG+ A++ + K+ + + IP Sbjct: 311 -------TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVL-IP 348
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 32.4 bits (74), Expect = 0.006 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 5/54 (9%) Query: 257 AYLAAIKEQNGAAMSLGRTSTFLDIYAERDLKAGVITESEV-QEIIDHFIMKLR 309 +AA+ A LGRT +I A R +K GVI + V ++++ HFI ++ Sbjct: 50 KSVAAVGHD--AKQMLGRTPG--NIAAIRPMKDGVIADFFVTEKMLQHFIKQVH 99
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 29.5 bits (66), Expect = 0.047 Identities = 39/270 (14%), Positives = 83/270 (30%), Gaps = 46/270 (17%) Query: 48 IPDWYLGSILNRLGDQIYYAKELTNKYEYGEKEYKQAIDKLMTRVLGEDHYLLEKKK--- 104 I D LG L +++Y + + Y +K Y +D+ T + L+ K Sbjct: 634 ISDSLLGLSFKDLNNKLY--EIYSKNIVYFKKIYFSFLDQWWTEYYSQYFELICMAKQSI 691 Query: 105 -AQYEAYKKWFEKHKSENPHSSLKKIKFDDFDLYRL-TKKEYNELHQSLKEAVDEFNSEV 162 AQ K+ + ++ S I D L R T+K + +L + +++ ++ + Sbjct: 692 LAQESLVKQIVQNKFTD---LSKASIPPDTLKLIRETTEKTFIDLSNESQISMNRVDNFL 748 Query: 163 KN--IQSKQKDLLPYDEATENRVTNGIYDFVCEIDTLYAAYFNHSQYGHNAKELRAKLDI 220 I +D+ P + + ++ I+ +E + Sbjct: 749 NKASICVFVEDIYPK-------FISYMEKYINNINI-------------KTREFIQRCTN 788 Query: 221 ILGDAKDPVRITNERIRKEMMDDLNSIIDDFFMDTNMNRPLNITKFNPNIHDYTNKPENR 280 I NE+ +I F ++ FN + + + Sbjct: 789 IN---------DNEKSILINSYTFKTIDFKFLDIQSIK-----NFFNSQVEQVMKEILSP 834 Query: 281 DNFDKLVKETREAVANADESWKTRTVKNYG 310 + + D S K ++ Sbjct: 835 YQLLLFASKGPNSNIIEDISGKNTLIQYTE 864
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.1 bits (67), Expect = 0.030 Identities = 17/89 (19%), Positives = 31/89 (34%), Gaps = 3/89 (3%) Query: 84 KFQSEVDNNASAILDE--DEIKKYKKDIDDALKDVFKSSKDANGAISDVSDLTTAKKIKT 141 EV NN +L + D I KY + VF K + + V T K Sbjct: 227 SADPEVINNCIYVLSDFKDNIDKYGSN-YSKGNAVFNLMKGIDYYTNSVIYNTKGYDAKN 285 Query: 142 ENLANKMGDFNKDIDQTVERLTTFDANNS 170 N++ + + ++ + +N+ Sbjct: 286 TEFYNRIDPYMERLESLCTIGDKLNNDNA 314
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 34.6 bits (79), Expect = 9e-06 Identities = 14/64 (21%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 15 GPTSLVVISIIALIIFGPKKLPQ----FGRAIGSTLKEFKSATEDLDKESHDTPSKESKQ 70 G + L+++ II L++ GP++LP I + + +L +E ++S + Sbjct: 5 GFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLK 64 Query: 71 QREQ 74 + E+ Sbjct: 65 KVEK 68
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.015 Identities = 13/29 (44%), Positives = 14/29 (48%) Query: 36 LIGKNGSGKSTLINILVGNRHKDNGSITF 64 L G G GKSTLIN LVG + Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDI 629
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 34.6 bits (79), Expect = 7e-05 Identities = 22/146 (15%), Positives = 46/146 (31%), Gaps = 12/146 (8%) Query: 1 MTPGQIRYYFPNHSELLNAVMSTVELKVRRRIEAIFKSENLTTIDKAKASLLTVLPLD-- 58 +T G I ++F + S+L + + E + + + L+ VL Sbjct: 43 VTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT 102 Query: 59 -KERLADMEVWMAFRNDIHEYGQSTLDDGLDQLCNSILTLLK-------NDHLLKNNVNI 110 + R ME+ F + + LC ++ +L ++ Sbjct: 103 EERRRLLMEII--FHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT 160 Query: 111 HLNSMKLHALIDGLALHKLLNPNGVS 136 ++ + I GL + L P Sbjct: 161 RRAAIIMRGYISGLMENWLFAPQSFD 186
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 281 bits (719), Expect = e-100 Identities = 87/180 (48%), Positives = 124/180 (68%), Gaps = 11/180 (6%) Query: 1 MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEAPYLKSYQDEEDEEDEE 60 MI +M ++KD +KP+EPF V G++IP +EN WT+TE + PY K Y+D++ + Sbjct: 1 MIMKMTHLNMKDFNKPNEPFVVFGRMIPAFENGVWTYTEERFSKPYFKQYEDDDMD---- 56 Query: 61 ADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDIAVCKDFRGQGIGSALINI 120 + Y++ K +LYY ++ C+G++K+R NWN YA IEDIAV KD+R +G+G+AL++ Sbjct: 57 ---VSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHK 113 Query: 121 SIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDTMLYANF----EKAVFWYLRF 176 +IEWAK + GLMLETQD N+ AC FY F IG+VDTMLY+NF E A+FWY +F Sbjct: 114 AIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSNFPTANEIAIFWYYKF 173
>adhesinb#Adhesin B signature. Length = 310 Score = 31.7 bits (72), Expect = 0.001 Identities = 34/166 (20%), Positives = 59/166 (35%), Gaps = 18/166 (10%) Query: 2 KLKSLAVLSMSAVVLTACGNDTPKDETKSTESNTNQDTNTTKDV---IALKDVKTS---- 54 K + L +L ++ V L AC + ET S++ N + D+ IA + Sbjct: 3 KCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSIVP 62 Query: 55 ----PEDAVKKAEETYKGQKLK-----GISFENSNGEWAYKVTQQ-KSGEESEVLVADKN 104 P + E+ K + GI+ E W K+ + K E + + Sbjct: 63 VGQDPHEYEPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVSEG 122 Query: 105 KKVINKKTEKE-DTMNENDNFKYSDAIDYKKAIKEGQKEFDGDIKE 149 VI + + E + + + I Y + I + E D KE Sbjct: 123 VDVIYLEGQSEKGKEDPHAWLNLENGIIYAQNIAKRLSEKDPANKE 168
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 30.9 bits (70), Expect = 0.004 Identities = 29/167 (17%), Positives = 62/167 (37%), Gaps = 32/167 (19%) Query: 1 MNIMLTGATGHLGTHITNQAIANHIDHFHIGVRNV----------EKVPEDWRGKVPVRQ 50 M ++TGA G +G H++ + + H +G+ N+ ++ + + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEA--GHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHK 58 Query: 51 LDYFNQESMVEAFK--GMDTVVFI-------PSIIHP-SFKRIPEV--ENLVYAAKQSGV 98 +D ++E M + F + V S+ +P ++ N++ + + + Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 99 AHIIFIG---YYADQHNNPFHMS-----PYFGYAARLLATSGIDYTY 137 H+++ Y PF P YAA A + +TY Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTY 165
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 89.3 bits (221), Expect = 6e-24 Identities = 50/212 (23%), Positives = 86/212 (40%), Gaps = 14/212 (6%) Query: 21 ITSNVQSVQAKAEVKQQSESELKHYYNKPILERKNVTGFKYTDEGKHYLEVTVGQQHSRI 80 ++SN AKA + +L +Y+ N D + + + Sbjct: 29 LSSNQIIKTAKASTNDNIK-DLLDWYSSGSDTFTNSEVL---DNSLGSMRIKNTDGSISL 84 Query: 81 TLLGSDKDKFKDGENSNIDVFILREGDSRQATN-----YSIGGVTKSNSVQYIDYINTPI 135 + S + +D+ R S+ + + I GVT + + I P Sbjct: 85 IIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLP--TPIELP- 141 Query: 136 LEIKKDNEDV-LKDFYYISKEDISLKELDYRLRERAIKQHGLYSNGLKQGQI-TITMNDG 193 L++K +D LK K+ +++ LD+ +R + + HGLY + K G ITMNDG Sbjct: 142 LKVKVHGKDSPLKYGPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDG 201 Query: 194 TTHTIDLSQKLEKERMGESIDGTKINKILVEM 225 +T+ DLS+K E I+ +I I E+ Sbjct: 202 STYQSDLSKKFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 88.2 bits (218), Expect = 2e-23 Identities = 38/203 (18%), Positives = 78/203 (38%), Gaps = 22/203 (10%) Query: 37 ISENSKKLKAYYNQPSIEYKNVTGYISFIQPSIKFMNIIDGNSVNNIALIGKDKQHYHTG 96 ++N K L +Y+ S + N + S+ M I + + ++ + Sbjct: 42 TNDNIKDLLDWYSSGSDTFTN----SEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFT 97 Query: 97 VHRNLNIFYVN-----EDKRFEGAKYSIGGITSANDKA--VDLIAEARVIKEDHTGEYDY 149 +++ + I G+T+ ++L + +V +D +Y Sbjct: 98 KGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYGP 157 Query: 150 DFFPFKIDKEAMSLKEIDFKLRKYLIDNYGLYGEMST----GKITVKKKYYGKYTFELDK 205 F DK+ +++ +DF++R L +GLY KIT+ Y +L K Sbjct: 158 KF-----DKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDG--STYQSDLSK 210 Query: 206 KLQEDRMSDVINVTDIDRIEIKV 228 K + + IN+ +I IE ++ Sbjct: 211 KFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 80.9 bits (199), Expect = 7e-20 Identities = 42/231 (18%), Positives = 81/231 (35%), Gaps = 25/231 (10%) Query: 132 VTTPPSTNTPQPMQSTKSDTPQSPTIKQAQTDMTPKYEDLRAYYTKPSFEFEKQFGFMLK 191 + T + TP P+ S + IK A+ +DL +Y+ S F + Sbjct: 17 LATTATDFTPVPLSSNQ-------IIKTAKASTNDNIKDLLDWYSSGSDTF-TNSEVLDN 68 Query: 192 PWTTVRFMNVIPNRFIYKIALVGKDEKKYKDGPYDNIDV-----FIVLEDNKYQLKKYSV 246 ++R N + + + + +D+ ++ + + Sbjct: 69 SLGSMRIKNTDGSI---SLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQI 125 Query: 247 GGITKTNSKKVNHKVELSITKKDNQGMISRDVSEYMITKEEISLKELDFKLRKQLIEKHN 306 G+T T ++ L + + K+++++ LDF++R QL + H Sbjct: 126 SGVTNTEKLPTPIELPLKVKVHGKDSPLKYG---PKFDKKQLAISTLDFEIRHQLTQIHG 182 Query: 307 LYGNM--GSGTIVIKMKNGGKYTFELHKKLQEHRMA----GTNIDNIEVNI 351 LY + G I M +G Y +L KK + + I IE I Sbjct: 183 LYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 94.7 bits (235), Expect = 3e-25 Identities = 44/223 (19%), Positives = 79/223 (35%), Gaps = 21/223 (9%) Query: 92 TPQPMQSTKSDTPQSPTTKQVPTEINPKFKDLRAYYTKPSLEFKNEIGIILKKWTTIRFM 151 TP P+ S + K N KDL +Y+ S F N ++ ++R Sbjct: 25 TPVPLSSNQ-------IIKTAKASTNDNIKDLLDWYSSGSDTFTN-SEVLDNSLGSMRIK 76 Query: 152 NVVPDYFIYKIALVGKDDKKYGEGVHRNVDV-----FVVLEENNYNLEKYSVGGITKSNS 206 N + + VD+ + + + G+T + Sbjct: 77 NTDGSI---SLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEK 133 Query: 207 KKVDHKAGVRITKEDNKGTISHDVSEFKITKEQISLKELDFKLRKQLIEKNNLYGNV--G 264 + +++ + + K K+Q+++ LDF++R QL + + LY + Sbjct: 134 LPTPIELPLKVKVHGKDSPLKYG---PKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKT 190 Query: 265 SGKIVIKMKNGGKYTFELHKKLQENRMADVIDGTNIDNIEVNI 307 G I M +G Y +L KK + N I+ I IE I Sbjct: 191 GGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 134 bits (339), Expect = 4e-41 Identities = 50/206 (24%), Positives = 74/206 (35%), Gaps = 14/206 (6%) Query: 34 KAKYENVTKDIFDLRDYYSGASKELKNVTGYRYSKGGKHYLIFDKNRKFTRVQIFGKDIE 93 K + +I DL D+YS S N S G + + IF Sbjct: 36 KTAKASTNDNIKDLLDWYSSGSDTFTNSEVLDNSLGS---MRIKNTDGSISLIIFPSPYY 92 Query: 94 RFKARKNPGLDI-----FVVKEAENRNGTVFSYGGVTKKNQDAYYDYINAPRFQIKRDEG 148 K +D+ + F GVT + I P +K Sbjct: 93 SPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLP--TPIELPLK-VKVHGK 149 Query: 149 DGIATYGRVHYIYKEEISLKELDFKLRQYLIQNFDLYKKFPKDSKI-KVIMKDGGYYTFE 207 D YG K+++++ LDF++R L Q LY+ K K+ M DG Y + Sbjct: 150 DSPLKYG--PKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSD 207 Query: 208 LNKKLQTNRMSDVIDGRNIEKIEANI 233 L+KK + N I+ I+ IEA I Sbjct: 208 LSKKFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 89.3 bits (221), Expect = 8e-24 Identities = 42/216 (19%), Positives = 83/216 (38%), Gaps = 12/216 (5%) Query: 18 TGVITTESQTVKAAESTQGQHNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRK 77 T V + +Q +K A+++ + L +Y S S N + L + + + Sbjct: 25 TPVPLSSNQIIKTAKASTNDNIKDLLDWYSSG-SDTFTNSEVLDNSLGSMR---IKNTDG 80 Query: 78 DYFVGLLGKDIEKYPQGEHDKQD-----AFLVIEEETVNGRQYSIGGLSKTNSKEFSKEV 132 + + + +K D + I G++ T E+ Sbjct: 81 SISLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIEL 140 Query: 133 DVKVTRKIDESSEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVK 192 +KV + S KF K+++++ LDF++R +L + LY + + G + Sbjct: 141 PLKVKVH-GKDSPLKYGPKFD--KKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKIT 197 Query: 193 MEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVEL 228 M D Y +L+KK + + I+ +IK I E+ Sbjct: 198 MNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 197 bits (501), Expect = 1e-65 Identities = 48/196 (24%), Positives = 82/196 (41%), Gaps = 16/196 (8%) Query: 42 DIKDLHRYYSSESFEFSNI--------SGKVENYNGSNVVRFNQENQNHQLFLLGKDKEK 93 +IKDL +YSS S F+N S +++N +GS + F G+ Sbjct: 45 NIKDLLDWYSSGSDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGE---- 100 Query: 94 YKEGIEGKDVFVVKELIDPNGRLSTVGGVTKKNNKSSETNTHLFVNKVYGGNLDASIDSF 153 K + K + + + GVT + L V KV+G + Sbjct: 101 -KVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELPLKV-KVHGKDSPLKYGP- 157 Query: 154 SINKEEVSLKELDFKIRQHLVKNYGLYKGTTKYGKI-TINLKDGEKQEIDLGDKLQFERM 212 +K+++++ LDF+IR L + +GLY+ + K G I + DG + DL K ++ Sbjct: 158 KFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTE 217 Query: 213 GDVLNSKDINKIEVTL 228 +N +I IE + Sbjct: 218 KPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 124 bits (313), Expect = 2e-37 Identities = 47/199 (23%), Positives = 73/199 (36%), Gaps = 19/199 (9%) Query: 42 DTNKLHQYYSGPSYELTNV--------SGQSQGYYDSNVLLFNQQNQKFQVFLLGKDENK 93 + L +YS S TN S + + S L+ F G+ Sbjct: 45 NIKDLLDWYSSGSDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGE---- 100 Query: 94 YKEKTHGLDVFAVPELVDLDGRIFSVSGVTKKNVKSIFESLRTPNLLVKKIDDKDGFSID 153 K + + F +SGVT L L K+ KD + Sbjct: 101 -KVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELP----LKVKVHGKDSP-LK 154 Query: 154 EFFFIQKEEVSLKELDFKIRKLLIKKYKLYEGSA-DKGRIVINMKDENKYEIDLSDKLDF 212 K+++++ LDF+IR L + + LY S G I M D + Y+ DLS K ++ Sbjct: 155 YGPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEY 214 Query: 213 ERMADVINSEQIKNIEVNL 231 IN ++IK IE + Sbjct: 215 NTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 132 bits (332), Expect = 3e-40 Identities = 39/197 (19%), Positives = 71/197 (36%), Gaps = 15/197 (7%) Query: 43 INMLHQYYSEESFEPTNISVKSEDYYGSNVLNFKQRNKAFKVFLLGDDKNKY------KE 96 I L +YS S TN V + K + + + + K Sbjct: 46 IKDLLDWYSSGSDTFTNSEVLD---NSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGEKV 102 Query: 97 KTHGLDVFAVPELIDIKGGIYSVGGITKKNVRSVFGFVSNPSLQVKKVDAKNGFSINELF 156 + + + + G+T + P L+VK + F Sbjct: 103 DLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLP--TPIELP-LKVKVHGKDSPLKYGPKF 159 Query: 157 FIQKEEVSLKELDFKIRKLLIEKYRLYKGTS-DKGRIVINMKDEKKHEIDLSEKLSFERM 215 K+++++ LDF+IR L + + LY+ + G I M D ++ DLS+K + Sbjct: 160 --DKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTE 217 Query: 216 FDVMDSKQIKNIEVNLN 232 ++ +IK IE +N Sbjct: 218 KPPINIDEIKTIEAEIN 234
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 193 bits (491), Expect = 4e-64 Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 10/202 (4%) Query: 31 KQNQKSVNKHDKEALYRYYTGKTMEMKNISALKHGKNNLRFKFRGIKIQVLLPGNDKSKF 90 K + S N + K+ L Y +G + N L + ++R K I +++ + Sbjct: 36 KTAKASTNDNIKDLLDWYSSG-SDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSP 94 Query: 91 QQRSYEGLDVFFVQEKRDKHD-----IFYTVGGVIQNNKTSGVVSAPILNISKEKGEDAF 145 E +D+ + K+ +H I + + GV K + P L + K G+D+ Sbjct: 95 AFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELP-LKV-KVHGKDSP 152 Query: 146 VKGYPYYIKKEKITLKELDYKLRKHLIEKYGLYKTISKDGRV-KISLKDGSFYNLDLRSK 204 +K Y K+++ + LD+++R L + +GLY++ K G KI++ DGS Y DL K Sbjct: 153 LK-YGPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKK 211 Query: 205 LKFKYMGEVIESKQIKDIEVNL 226 ++ I +IK IE + Sbjct: 212 FEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 108 bits (272), Expect = 2e-31 Identities = 43/225 (19%), Positives = 79/225 (35%), Gaps = 21/225 (9%) Query: 16 LTTGMITTTAQPVKASTLEVRSQAT-------QDLSEYYNRPFFEYTNQSGYKEEGKVTF 68 L T PV S+ ++ A +DL ++Y+ +TN Sbjct: 15 LLLATTATDFTPVPLSSNQIIKTAKASTNDNIKDLLDWYSSGSDTFTNSEVLDNSLGSMR 74 Query: 69 TPNYQLIDVTLTGNEKQNF-------GEDISNVDIFVVRENSDRSGNTASIGGITKTNGS 121 N + D++ + S+ + I G+T T Sbjct: 75 IKNTDGSISLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTE-- 132 Query: 122 NYIDKVKDVNLIITKNIDSVTSTSTSSTYTINKEEISLKELDFKLRKHLIDKHNLYKTEP 181 + L + + S +K+++++ LDF++R L H LY++ Sbjct: 133 ---KLPTPIELPLKVKVHGKDS-PLKYGPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSD 188 Query: 182 KDSKI-RITMKDGGFYTFELNKKLQTHRMGDVIDGRNIEKIEVNL 225 K +ITM DG Y +L+KK + + I+ I+ IE + Sbjct: 189 KTGGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEI 233
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 28.8 bits (64), Expect = 0.021 Identities = 16/82 (19%), Positives = 33/82 (40%), Gaps = 9/82 (10%) Query: 177 INSNVPSYDAKFKMSNKDENVKQLRSRYNIPTEKAPILKMHIDGDLKGSSVGYKKLEIDF 236 +N VP Y+AK D V Q + RY + + + S G +++ Sbjct: 124 VNEEVPGYNAKIVSIRPDRVVLQYQGRYEV---------LGLYSQEDSGSDGVPGAQVNE 174 Query: 237 SKEENSELSVVDSLNFQPAKKN 258 ++ + ++ D ++F P + Sbjct: 175 QLQQRASTTMSDYVSFSPIMND 196
>adhesinb#Adhesin B signature. Length = 310 Score = 27.1 bits (60), Expect = 0.013 Identities = 21/94 (22%), Positives = 40/94 (42%), Gaps = 14/94 (14%) Query: 14 DISTTVETLNLISKMEAQKENIRTVIAPEHKHKYKDIENGLKGEE---KVLIEQMAQHCE 70 +S V+ + L + E KE+ H + ++ENG+ + K L E+ + E Sbjct: 118 AVSEGVDVIYLEGQSEKGKED---------PHAWLNLENGIIYAQNIAKRLSEKDPANKE 168 Query: 71 AFKANFKGAAQ--GDWVKSAMSEIDSIKDDLKKI 102 ++ N K + K A + ++I + K I Sbjct: 169 TYEKNLKAYVEKLSALDKEAKEKFNNIPGEKKMI 202
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.8 bits (82), Expect = 0.001 Identities = 43/234 (18%), Positives = 87/234 (37%), Gaps = 6/234 (2%) Query: 22 KFSIRKYTVGTASILVGTTLI-FGLGNQ-EAKAAESTNKELNE--ATTSASDNQSSDKVD 77 +S+RK GTAS+ V T++ GL +A +T + + +D + Sbjct: 9 HYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTLEKVQERADKFEIENNT 68 Query: 78 MQQLNQEDNTKNDNQKEMVSSQGNETTSNGNKLIEKESVQSTTGNKVEVSTAKSDE--QA 135 ++ N + + N K+ E ++ KL + + S +K++ A+ + +A Sbjct: 69 LKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKA 128 Query: 136 SPKSTNEDLNTKQTISNQEALQPDLQENKSVVNVQPTNEENKKVDAKTESTTLNVKSDAI 195 + N I EA + L K+ + N + TL + A+ Sbjct: 129 LEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 188 Query: 196 KSNDETLVDNNSNSNNENNADIILPKSTAPKRLNTRMRIAAVQPSSTEAKNVND 249 ++ L + N + AD K+ ++ R A ++ + A N + Sbjct: 189 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST 242
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.7 bits (155), Expect = 5e-14 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 1/111 (0%) Query: 3 ILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYW 62 IL+ +DD + L + L + ++V + + + + ++V+ DV +P + F Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 63 CRKMREV-SNVPILFLSSRDNPMDQVMSMELGADDYMQKPFYTNVLIAKLQ 112 ++++ ++P+L +S+++ M + + E GA DY+ KPF LI + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF05272#Virulence-associated E family protein Length = 892 Score = 36.2 bits (83), Expect = 1e-04 Identities = 15/56 (26%), Positives = 26/56 (46%), Gaps = 8/56 (14%) Query: 40 GPSGSGKTTLLNVLSSIDYISQGSITLKGKK--LEKLSNK------ELSDIRKHDI 87 G G GK+TL+N L +D+ S + K E+++ E++ R+ D Sbjct: 603 GTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRRADA 658
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 56.8 bits (137), Expect = 5e-11 Identities = 73/365 (20%), Positives = 134/365 (36%), Gaps = 41/365 (11%) Query: 11 KNYKLFVA--NMFLLGMGIAVTVPYLVLFATKDLGMTTNQ---YGLLLASAAISQFTVNS 65 N L V + L +GI + +P L +DL + + YG+LLA A+ QF Sbjct: 3 PNRPLIVILSTVALDAVGIGLIMPVLP-GLLRDLVHSNDVTAHYGILLALYALMQFACAP 61 Query: 66 IIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYA 125 ++ SD F R+ +++++L A+ ++I +W+ + + I G+ Sbjct: 62 VLGALSD--RFGRRPVLLVSLAGAAVDYAIMATAPFLWV-LYIGRIVAGITGATGA---V 115 Query: 126 SARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISIILFT 185 + +++ +RA+ + + F G + GP +G + G +A F L Sbjct: 116 AGAYIADITDGDERARHFG-FMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNF 174 Query: 186 LVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTL--------LLPFIAFILLHIGQWM 237 L + ++ + + A N L + FI+ +GQ Sbjct: 175 LTGCFLLPESHK-----GERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVP 229 Query: 238 YTMNMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIIL-GVLSSRLQTRTLLIYGAIFGG 296 + +F D + +G + L ++ G +++RL R L+ G I G Sbjct: 230 AAL-WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADG 288 Query: 297 LFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQ 356 Y + +M F + L GIG +P S GQ Sbjct: 289 TGYILLAFATRGWM-----AFPIMVLLASGGIG-------MPALQAMLSRQVDEERQ-GQ 335 Query: 357 LGGNL 361 L G+L Sbjct: 336 LQGSL 340 Score = 49.1 bits (117), Expect = 2e-08 Identities = 44/186 (23%), Positives = 73/186 (39%), Gaps = 13/186 (6%) Query: 215 MFKDKTLLLPFIAFILLHIGQWMYTMNMPLFVTDYLKENEQ--HVGYLASLCAGLEVPFM 272 M ++ L++ L +G + +P + D + N+ H G L +L A ++ Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 273 IILGVLSSRLQTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISY 332 +LG LS R R +L+ + Y + +++ G++ I A G +Y Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AY 119 Query: 333 FQDILPD-----FPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGM 387 DI G+ S F MV G + G L+GG H FF +AA L Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPH-----APFFAAAALNGLNF 174 Query: 388 ILIFFT 393 + F Sbjct: 175 LTGCFL 180
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 26.7 bits (59), Expect = 0.049 Identities = 13/37 (35%), Positives = 19/37 (51%), Gaps = 2/37 (5%) Query: 135 MYDIYP-PYDGIPDEAFLI-KELKVNSLAGKTGTINY 169 D+ P P GI L KE+K++ +A GT+ Y Sbjct: 305 AVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGY 341
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 35.1 bits (80), Expect = 0.001 Identities = 56/298 (18%), Positives = 104/298 (34%) Query: 566 GSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSDN 625 GS + +S + GS T+ GSD + S + + S + S + +S Sbjct: 357 GSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQ 416 Query: 626 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 685 + S + SD + S + DS + S + DS + S + Sbjct: 417 TAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQK 476 Query: 686 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 745 SD + S S + +S + S + S + S + ++SD + S S Sbjct: 477 GSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTS 536 Query: 746 DSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 805 + ++S + S + +S + S + SD + S + SDS + Sbjct: 537 TAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGY 596 Query: 806 DSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSSDSDSESDSNSDS 863 S + S + S + S + S S +G+DS + S + +S Sbjct: 597 GSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNS 654 Score = 35.1 bits (80), Expect = 0.002 Identities = 62/321 (19%), Positives = 111/321 (34%), Gaps = 4/321 (1%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDS 611 G E + S G S + +DS +G ST +G +S+ + S SD Sbjct: 181 GSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQMAGYGSTQTGMKGSDL 240 Query: 612 ASDSDSASDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 671 + S + DS + S + DS + S + SD + S Sbjct: 241 TAGYGSTGTA----GDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTG 296 Query: 672 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 731 + +DS + S + +S + S + SD + S + DS + Sbjct: 297 TAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGY 356 Query: 732 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDS 791 S + DS + S + SD + S + +DS + S + +S Sbjct: 357 GSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQ 416 Query: 792 DSDSDSDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSS 851 + S + SD + S + DS + S + DS+ + GS + Sbjct: 417 TAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQK 476 Query: 852 DSDSESDSNSDSESGSNNNVV 872 SD + S S +G ++++ Sbjct: 477 GSDLTAGYGSTSTAGYESSLI 497 Score = 35.1 bits (80), Expect = 0.002 Identities = 59/314 (18%), Positives = 107/314 (34%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDS 611 G + E+S G S S +G ST +G DS+ + S + DS Sbjct: 213 GSTQTAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSL 272 Query: 612 ASDSDSASDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 671 + S + +D + S + +DS + S + +S + S + Sbjct: 273 TAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQK 332 Query: 672 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 731 SD + S + DS + S + DS + S + SD + S Sbjct: 333 GSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTG 392 Query: 732 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDS 791 + +DS + S + +S + S + SD + S + DS + Sbjct: 393 TAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGY 452 Query: 792 DSDSDSDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSS 851 S + DS + S ++ SD + S S + +S + S + S+ Sbjct: 453 GSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTL 512 Query: 852 DSDSESDSNSDSES 865 + S + +ES Sbjct: 513 TAGYGSTQTAQNES 526 Score = 35.1 bits (80), Expect = 0.002 Identities = 56/299 (18%), Positives = 105/299 (35%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDS 611 G + EDS G S + S +G ST +G+DS+ + S + +S Sbjct: 261 GSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQ 320 Query: 612 ASDSDSASDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 671 + S + +D + S + DS + S + DS + S + Sbjct: 321 TAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQK 380 Query: 672 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 731 SD + S + +DS + S + +S + S + SD + S Sbjct: 381 GSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTG 440 Query: 732 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDS 791 + DS + S + DS + S + SD + S S + +S + Sbjct: 441 TAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGY 500 Query: 792 DSDSDSDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSS 850 S + S + S ++++SD + S S + ++S + S + +S Sbjct: 501 GSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSV 559 Score = 35.1 bits (80), Expect = 0.002 Identities = 56/299 (18%), Positives = 104/299 (34%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDS 611 G + EDS G S + S +G ST +G+DS+ + S + +S Sbjct: 357 GSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQ 416 Query: 612 ASDSDSASDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 671 + S + +D + S + DS + S + DS + S + Sbjct: 417 TAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQK 476 Query: 672 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 731 SD + S S + +S + S + S + S + ++SD + S S Sbjct: 477 GSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTS 536 Query: 732 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDS 791 + ++S + S + +S + S + SD + S + SDS + Sbjct: 537 TAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGY 596 Query: 792 DSDSDSDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSS 850 S + S + S + S + S S + +DS + S + +S Sbjct: 597 GSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSI 655 Score = 34.0 bits (77), Expect = 0.004 Identities = 61/321 (19%), Positives = 116/321 (36%), Gaps = 4/321 (1%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDS 611 G + + SD G S + DS +G ST +G DS+ + S + SD Sbjct: 325 GSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDL 384 Query: 612 ASDSDSASDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 671 + S + +DS + S + +S + S + SD + S Sbjct: 385 TAGYGSTGTA----GADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTG 440 Query: 672 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 731 + DS + S + DS + S + SD + S S + +S + Sbjct: 441 TAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGY 500 Query: 732 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDS 791 S + S + S + ++SD + S S + ++S + S + +S Sbjct: 501 GSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVL 560 Query: 792 DSDSDSDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSS 851 + S + SD + S + SDS + S + S+ + GS + Sbjct: 561 TAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTARE 620 Query: 852 DSDSESDSNSDSESGSNNNVV 872 S + S S +G++++++ Sbjct: 621 QSVLTTGYGSTSTAGADSSLI 641 Score = 33.2 bits (75), Expect = 0.006 Identities = 57/293 (19%), Positives = 103/293 (35%), Gaps = 2/293 (0%) Query: 560 DSDSDPGSDSGSDSNSDSGSD--SGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDS 617 +S + GS + GSD +G ST +G DS+ + S + DS + S Sbjct: 315 GEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGS 374 Query: 618 ASDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 677 + +D + S + +DS + S + +S + S + SD + Sbjct: 375 TQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTA 434 Query: 678 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 737 S + DS + S + DS + S + SD + S S + +S Sbjct: 435 GYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYES 494 Query: 738 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDS 797 + S + S + S + + SD + S S + ++S + S + Sbjct: 495 SLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTA 554 Query: 798 DSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSS 850 +S + S + SD + S + SDS + S + SS Sbjct: 555 SYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSS 607 Score = 33.2 bits (75), Expect = 0.006 Identities = 57/298 (19%), Positives = 102/298 (34%) Query: 566 GSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSDN 625 GS + S + GS T+ GSD + S + S + S + DS Sbjct: 309 GSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSL 368 Query: 626 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 685 + S + SD + S + +DS + S + +S + S + Sbjct: 369 TAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQK 428 Query: 686 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 745 SD + S + DS + S + DS + S + SD + S S Sbjct: 429 GSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTS 488 Query: 746 DSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 805 + +S + S + S + S + ++SD + S S + ++S + Sbjct: 489 TAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGY 548 Query: 806 DSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSSDSDSESDSNSDS 863 S + S + S + SD + S +GSDS + S ++ S Sbjct: 549 GSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHS 606 Score = 33.2 bits (75), Expect = 0.007 Identities = 54/281 (19%), Positives = 101/281 (35%) Query: 575 SDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSDNDSDSDSDSD 634 S + GSD T+ GS + DS+ + S + DS + S + SD Sbjct: 422 STQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLT 481 Query: 635 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 694 + S S + +S + S + S + S + ++SD + S S + ++ Sbjct: 482 AGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGAN 541 Query: 695 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 754 S + S + +S + S + SD + S + SDS + S Sbjct: 542 SSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQT 601 Query: 755 SDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSDSE 814 + S + S + S + S S + +DS + S + +S + Sbjct: 602 ASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYG 661 Query: 815 SDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSSDSDS 855 S + SD + S S + + S +G S ++ +S Sbjct: 662 STQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNS 702 Score = 32.8 bits (74), Expect = 0.007 Identities = 56/298 (18%), Positives = 97/298 (32%) Query: 566 GSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSDN 625 GS S + GS T+ S + S + + S + S + +S Sbjct: 165 GSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQ 224 Query: 626 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 685 + S SD + S + DS + S + DS + S + Sbjct: 225 MAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQK 284 Query: 686 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 745 SD + S + +DS + S + +S + S + SD + S Sbjct: 285 GSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTG 344 Query: 746 DSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 805 + DS + S + DS+ + S + SD + S + +DS + Sbjct: 345 TAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGY 404 Query: 806 DSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSSDSDSESDSNSDS 863 S + ES + S + SD + S +G DS + S + DS Sbjct: 405 GSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDS 462 Score = 32.8 bits (74), Expect = 0.007 Identities = 57/298 (19%), Positives = 104/298 (34%) Query: 566 GSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSDN 625 GS + S + GS T+ GSD + S + S + S + DS Sbjct: 405 GSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSL 464 Query: 626 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 685 + S + SD + S S + +S + S + S + S + + Sbjct: 465 TAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQN 524 Query: 686 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 745 +SD + S S + ++S + S + +S + S + SD + S Sbjct: 525 ESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTG 584 Query: 746 DSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 805 + SDS + S + S+ + S + S + S S + +DS + Sbjct: 585 TAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGY 644 Query: 806 DSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSSDSDSESDSNSDS 863 S + S + S + SD + S S +G+DS + S + +S Sbjct: 645 GSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNS 702 Score = 32.8 bits (74), Expect = 0.008 Identities = 58/307 (18%), Positives = 108/307 (35%), Gaps = 2/307 (0%) Query: 559 EDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSD--SASDSD 616 +DS G S + DS +G ST + S + S + +DS + S Sbjct: 252 DDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGST 311 Query: 617 SASDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 676 + +S + S + SD + S + DS + S + DS + Sbjct: 312 QTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAG 371 Query: 677 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 736 S + SD + S + +DS + S + +S + S + SD Sbjct: 372 YGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSD 431 Query: 737 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSD 796 + S + DS + S + DS+ + S + SD + S S + Sbjct: 432 LTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAG 491 Query: 797 SDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSSDSDSE 856 +S + S + S + S + ++SD + S S +G++S + S Sbjct: 492 YESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGST 551 Query: 857 SDSNSDS 863 ++ +S Sbjct: 552 QTASYNS 558 Score = 32.8 bits (74), Expect = 0.008 Identities = 56/299 (18%), Positives = 106/299 (35%) Query: 552 GEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDS 611 G + E+S G S + S +G ST +G DS+ + S + DS Sbjct: 405 GSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSL 464 Query: 612 ASDSDSASDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 671 + S + +D + S S + +S + S + S + S + + Sbjct: 465 TAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQN 524 Query: 672 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 731 +SD + S S + ++S + S + +S + S + SD + S Sbjct: 525 ESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTG 584 Query: 732 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDS 791 + SDS + S + S + S + S + S S + +DS + Sbjct: 585 TAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGY 644 Query: 792 DSDSDSDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSS 850 S + +S + S ++ SD + S S + +DS + S + +S Sbjct: 645 GSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSI 703 Score = 31.6 bits (71), Expect = 0.018 Identities = 58/293 (19%), Positives = 109/293 (37%), Gaps = 6/293 (2%) Query: 569 SGSDSNSDSG----SDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSA--SDSD 622 +G+DS+ +G +G +ST +G S + SD + S + DS+ + Sbjct: 394 AGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYG 453 Query: 623 SDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 682 S + DS + S + SD + S S + +S + S + S Sbjct: 454 STQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLT 513 Query: 683 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 742 + S + ++SD + S S + ++S + S + +S + S + Sbjct: 514 AGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREG 573 Query: 743 SDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 802 SD + S + SDS + S + S + S + S + S S Sbjct: 574 SDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTST 633 Query: 803 SDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSSDSDS 855 + +DS + S + +S + S + SD +G S S++ +DS Sbjct: 634 AGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADS 686 Score = 31.6 bits (71), Expect = 0.018 Identities = 60/313 (19%), Positives = 109/313 (34%), Gaps = 4/313 (1%) Query: 561 SDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASD 620 S G DS + S +G DS+ +G S + SD + S + +DS+ Sbjct: 246 STGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLI 305 Query: 621 SDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 680 + + + +S + S + SD + S + DS + S + D Sbjct: 306 AGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGED 365 Query: 681 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 740 S + S + SD + S + +DS + S + +S + S Sbjct: 366 SSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQT 425 Query: 741 SDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 800 + SD + S + DS + S + DS + S + SD + Sbjct: 426 AQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYG 485 Query: 801 SDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSD----SGSDSDSSSDSDSE 856 S S + ES + S + S + S + ++SD GS S + ++S Sbjct: 486 STSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLI 545 Query: 857 SDSNSDSESGSNN 869 + S + N+ Sbjct: 546 AGYGSTQTASYNS 558 Score = 31.3 bits (70), Expect = 0.022 Identities = 57/328 (17%), Positives = 108/328 (32%) Query: 545 PEQPDEPGEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSD 604 P PD E++ D+ +S S + + +T S S + Sbjct: 122 PGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQTIEIATYGSTLSGTHQSQLIAGYG 181 Query: 605 SASDSDSASDSDSASDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 664 S + +S + S +DS + S + +S + S SD Sbjct: 182 STETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQMAGYGSTQTGMKGSDLT 241 Query: 665 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 724 + S + DS + S + DS + S + SD + S + +D Sbjct: 242 AGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGAD 301 Query: 725 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSD 784 S + S + +S + S + SD + S + DS + S Sbjct: 302 SSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQT 361 Query: 785 SDSDSDSDSDSDSDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSG 844 + DS + S + SD + S + +DS + S + +S + G Sbjct: 362 AGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYG 421 Query: 845 SDSDSSSDSDSESDSNSDSESGSNNNVV 872 S + SD + S +G +++++ Sbjct: 422 STQTAQKGSDLTAGYGSTGTAGDDSSLI 449 Score = 31.3 bits (70), Expect = 0.027 Identities = 59/292 (20%), Positives = 108/292 (36%), Gaps = 2/292 (0%) Query: 561 SDSDPGSDSGSDSNSDSGSD--SGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSA 618 DS + GS + GSD +G STS +G +S+ + S + S + S Sbjct: 460 EDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGST 519 Query: 619 SDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 678 + +++D + S S + ++S + S + +S + S + SD + Sbjct: 520 QTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAG 579 Query: 679 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 738 S + SDS + S + S + S + S + S S + +DS Sbjct: 580 YGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSS 639 Query: 739 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 798 + S + +S + S + SD + S S + +DS + S + Sbjct: 640 LIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAG 699 Query: 799 SDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSS 850 +S + S ++ SD S S S + +DS + S + SS Sbjct: 700 YNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSS 751 Score = 30.9 bits (69), Expect = 0.028 Identities = 59/315 (18%), Positives = 111/315 (35%), Gaps = 4/315 (1%) Query: 561 SDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASD 620 S G+DS + S +G +ST +G S + SD + S + DS+ Sbjct: 294 STGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLI 353 Query: 621 SDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 680 + + + DS + S + SD + S + +DS + S + + Sbjct: 354 AGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEE 413 Query: 681 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 740 S + S + SD + S + DS + S + DS + S Sbjct: 414 STQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQT 473 Query: 741 SDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 800 + SD + S S + +S + S + S + S + ++SD + Sbjct: 474 AQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYG 533 Query: 801 SDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSD----SGSDSDSSSDSDSE 856 S S + + S + S + +S + S + SD GS + SDS Sbjct: 534 STSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSII 593 Query: 857 SDSNSDSESGSNNNV 871 + S + ++++ Sbjct: 594 AGYGSTQTASYHSSL 608 Score = 30.5 bits (68), Expect = 0.042 Identities = 58/298 (19%), Positives = 103/298 (34%) Query: 566 GSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSDN 625 GS + S + GS T+ + SD + S S + + S + S + +S Sbjct: 501 GSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVL 560 Query: 626 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 685 + S + SD + S + SDS + S + S + S + Sbjct: 561 TAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTARE 620 Query: 686 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 745 S + S S + +DS + S + +S + S + SD + S S Sbjct: 621 QSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTS 680 Query: 746 DSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 805 + +DS + S + +S + S + SD S S S + +DS + Sbjct: 681 TAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGY 740 Query: 806 DSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSSDSDSESDSNSDS 863 S + S + S + S + S S +G+DS + S + S Sbjct: 741 GSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHS 798
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.022 Identities = 39/228 (17%), Positives = 78/228 (34%), Gaps = 14/228 (6%) Query: 207 ERANKKAVNKRMLENKKEDLETIIDEFFSDIDKTRPNNIPVLEDEKQEEKNHKN---MAQ 263 E A N + E E D +T N V ++ K K + +AQ Sbjct: 1035 ETTETVAENSKQESKTVEKNE-------QDATETTAQNREVAKEAKSNVKANTQTNEVAQ 1087 Query: 264 LKSDTEAAKSDESKRSKRSKRSLNTQNHKPASQEVSEQQKAEYDKRAEERKARFLDNQKI 323 S+T+ ++ E+K + ++ + +QEV + K+ + + Sbjct: 1088 SGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAR 1147 Query: 324 KKTPVVSLEYDFEHKQRIDNENDKKLVVSAPTKKPTSPTTYTETTTQV---PMPTVERQT 380 + P V+++ + S+ ++P + +T T V P T T Sbjct: 1148 ENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATT 1207 Query: 381 QQQIIYNAPKQLAGLNGES-HDFTTTHQSPTTSNHTHNNVVEFEETSA 427 Q + + + + S + TTS++ + V + TS Sbjct: 1208 QPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTST 1255
>PF05704#Capsular polysaccharide synthesis protein Length = 307 Score = 27.5 bits (61), Expect = 0.035 Identities = 13/69 (18%), Positives = 24/69 (34%), Gaps = 7/69 (10%) Query: 116 EWVKKNYENTNHRYLVTLNLNSK-------KFTYCTKIIYQAYKFGVSEKSVKSYGLHII 168 W + Y N + +++ N + + YK + +Y HI Sbjct: 239 YWKEIPYVNNVNPHMLQYLGNLPYDNSMFNYIKSTSPVQKLTYKLDYNNLKRNTYYDHIF 298 Query: 169 SPYAIKDNF 177 S +KDN+ Sbjct: 299 SIDKLKDNY 307
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 34.1 bits (78), Expect = 5e-04 Identities = 16/48 (33%), Positives = 29/48 (60%) Query: 1 MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEK 48 MKKL L+++ A++L AC +G K + +K+ V A+ + A+I + Sbjct: 1 MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKN 48
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 28.1 bits (62), Expect = 0.024 Identities = 21/105 (20%), Positives = 44/105 (41%), Gaps = 11/105 (10%) Query: 70 LASPKHTEGLIRSIEGHYVGYELHDGKQLSISDMMASQLF------EDEYFM----YGLE 119 L S +HT L S+ + ++ GK L +++MM Q+ E+ + LE Sbjct: 61 LFSSEHTR-LYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLE 119 Query: 120 TYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLYQLAT 164 T N + + ++ + + + + +A + + QLA+ Sbjct: 120 TVVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLAS 164
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 36.2 bits (83), Expect = 6e-04 Identities = 17/143 (11%), Positives = 48/143 (33%), Gaps = 14/143 (9%) Query: 420 QLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQEKRAQLD 479 E+ +S + + Q + + ++EK + + + + + K+ Q + Sbjct: 1082 TNEVAQSGSETKE----TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSE 1137 Query: 480 ESRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEE 539 + E A+ N+ E Q + + ++ ++T + + VT+ Sbjct: 1138 TVQPQAEPARENDPTVNIKEPQ-------SQTNTTAD---TEQPAKETSSNVEQPVTEST 1187 Query: 540 IGDIVSQWTGIPVSKLVETEREK 562 + + P + T + Sbjct: 1188 TVNTGNSVVENPENTTPATTQPT 1210
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 84.6 bits (209), Expect = 5e-21 Identities = 46/253 (18%), Positives = 104/253 (41%), Gaps = 27/253 (10%) Query: 48 NPKRVVVLEYSFADYLAALDMKPVGIADDGSTK------NITKSVRDKIGAYESVGSRPQ 101 +P R+V LE+ + L AL + P G+AD + + + SV D VG R + Sbjct: 34 DPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVID-------VGLRTE 86 Query: 102 PNMEVISKLKPDLIIADVSRHKKIKSELSKIAPTIMLVSGTGDYNANI--EAFKTVAKAV 159 PN+E+++++KP ++ + + L++IAP G + ++ +A + Sbjct: 87 PNLELLTEMKPSFMVWS-AGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLL 145 Query: 160 GKEKEGEKRLEKHDKILAEIRKKIEQSTLKSAFAFGISRA-GMFINNEDTFMGQFLIKMG 218 + E L +++ + ++ + + + + M + ++ + L + G Sbjct: 146 NLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYG 205 Query: 219 IQPEVTKDKTTHVGERKGGPYIYLNNEELANI-NPKVMILATDGKTDKNRTKFIDPAVWK 277 I P + +T G ++ + LA + V+ D D + + +W+ Sbjct: 206 I-PNAWQGETNFWG------STAVSIDRLAAYKDVDVLCFDHDNSKDMD--ALMATPLWQ 256 Query: 278 SLKAVKDNKVYDV 290 ++ V+ + V Sbjct: 257 AMPFVRAGRFQRV 269
>PF05272#Virulence-associated E family protein Length = 892 Score = 407 bits (1048), Expect = e-131 Identities = 135/433 (31%), Positives = 193/433 (44%), Gaps = 39/433 (9%) Query: 362 DFDEIENSDDAWSE----TLEITSKGTFKASIPNIEIILRNDPNLKGKIAFNEFTKQIEC 417 D+ E+ W + L + + K + LR+ P L G +AF+E +Q Sbjct: 421 GGDDGEDPFGEWLDDEVARLRLRGRWLLKPRRAALIEALRSAPALAGCVAFDELREQPVA 480 Query: 418 LGKVPWNTNFKTRQWQDGDDSSLRSYIEKIYD-IHHSGKT-KDAIISVAMQNAYHPVRDY 475 + PW +D D L Y+E Y S +T + AI A N HP RD+ Sbjct: 481 VRAFPWRKA--PGPLEDADVLRLADYVETTYGTGEASAQTTEQAINVAADMNRVHPFRDW 538 Query: 476 LNKISWDGHKRLEKLFIKYLGVEDTEVN-------RTTTKKALTAGIARVMEPGCKFDYM 528 + WD RLEK + LG + + K L +ARVMEPGCKFDY Sbjct: 539 VKAQQWDEVPRLEKWLVHVLGKTPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYS 598 Query: 529 LTLYGPQGVGKSALLKKLGGA-WFSDSLVSV-TGKEAYEALQGVWLMEMAELAATRKAEV 586 + L G G+GKS L+ L G +FSD+ + TGK++YE + G+ E++E+ A R+A+ Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRRADA 658 Query: 587 EAIKHFISKQVDRFRVAYGHYIEDFPRQCIFIGTTNKVDFLRDETGGRRFWPMTVNPERV 646 EA+K F S + DR+R AYG Y++D PRQ + TTNK +L D TG RRFWP+ V P R Sbjct: 659 EAVKAFFSSRKDRYRGAYGRYVQDHPRQVVIWCTTNKRQYLFDITGNRRFWPVLV-PGRA 717 Query: 647 EVNWSKLTKDEIDQIWAEAKHYYEQGEYLFLNPELEEEMRSIQSKHTEESPYTGIIDEYL 706 + W + + Q++AEA H Y GE F +PE EE + +E Sbjct: 718 NLVWLQKFR---GQLFAEALHLYLAGERYFPSPEDEEIYFRPE----QELRLVE------ 764 Query: 707 NTPIPSNWDDLTIFERRRFYQGDVDMLPTGNVDYVKRNKVCALEVFVECFGKDKGDSRGS 766 L R G Y + V+ G D G S Sbjct: 765 ----TGVQGRLWALLTREGAPAAEGAAQKG---YSVNTTFVTIADLVQALGADPGKS-SP 816 Query: 767 MEIRKISNILRQL 779 M ++ + L + Sbjct: 817 MLEGQVRDWLNEN 829
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 37.4 bits (86), Expect = 1e-04 Identities = 29/121 (23%), Positives = 55/121 (45%), Gaps = 3/121 (2%) Query: 69 PLKMYEDYKVVNTDVSDLLTVSPNNSLSSFDFINQIETIRNEKGNAYVLIERD---IYHQ 125 PL +D++ D L T++ ++++S + + Q ++I N+ Y + ERD + H Sbjct: 194 PLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKNHPGYTIYERDSSIVTHD 253 Query: 126 PSKLFLLNPDVVEMLIENKSRELYYSIHAATGNKLIVHNMDMLHFKHIVASNMVQGISPI 185 + P E K+RE Y I+ +G ++N D++ K+ V + P Sbjct: 254 NDIFRTILPMDQEFTYRVKNREQAYRINKKSGLNEEINNTDLISEKYYVLKKGEKPYDPF 313 Query: 186 D 186 D Sbjct: 314 D 314
>INTIMIN#Intimin signature. Length = 939 Score = 30.0 bits (67), Expect = 0.004 Identities = 26/155 (16%), Positives = 55/155 (35%), Gaps = 23/155 (14%) Query: 1 MTKTLKVYKGDDVVASEQGEGKVSVTLSNLEADTTYPKGTYQVAWEENGRESSKV----- 55 +T T+KV KGD V++++ ++ + + T G +V S V Sbjct: 678 ITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVS 737 Query: 56 --------------DVPQFKTNPILVSGVSFTPETKSIMVNTDDNVEPNIAPSTATNKIL 101 I + G + ++ + ++ N Sbjct: 738 DVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYG----QVNLKASGGNGKY 793 Query: 102 KYTSEHPEFVTVDENTGAIHGVAEGTSVITAMSTD 136 + S +P +VD ++G + +GT+ I+ +S+D Sbjct: 794 TWRSANPAIASVDASSGQVTLKEKGTTTISVISSD 828
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 60.5 bits (146), Expect = 5e-11 Identities = 37/235 (15%), Positives = 76/235 (32%), Gaps = 11/235 (4%) Query: 72 YSQVEDELKQVNANYQKAKSSVKDVEKAYLKLVEANKKEKLALDKSKEALKSSNTELKKA 131 + + LK N++ ++KD + + K++ DKS S EL+ Sbjct: 62 FEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEAR 121 Query: 132 ENQYKRTNQRKQDAYQ----KLKQLRDAEQKLKNSNQATTAQLKRASDAVQKQSAKHKAL 187 + ++ + + K+K L + L L+ A + SAK K L Sbjct: 122 KADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTL 181 Query: 188 VEQYKQEGNQVQKLKVQNDNLSKSNDKIESSYAKTNTKLKQTEKEFNDLNNTIKNHSANV 247 + L+ + L K+ + + + K+K E E L + + Sbjct: 182 EAEK-------AALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKAL 234 Query: 248 AKAETAVNKEKAALNNLERSIDKASSEMKTFNKEQMIAQSHFGKLASQADVMSKK 302 A + A + LE + K A + +++ + + Sbjct: 235 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAE 289 Score = 58.2 bits (140), Expect = 3e-10 Identities = 33/239 (13%), Positives = 70/239 (29%), Gaps = 3/239 (1%) Query: 28 RQLGVVNSEMKANLSAFDKSEKSMEKYQARIKGLNDRLKVQKKMYSQVEDELKQVNANYQ 87 L + NS++ N A + + + K + + EL+ A+ + Sbjct: 67 NTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLE 126 Query: 88 KAKSSVKDVEKAYLKLVEANKKEKLALDKSKEALKSSNTELKKAENQYKRTNQRKQDAYQ 147 KA + K + L+ A N + + + Sbjct: 127 KAL---EGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEA 183 Query: 148 KLKQLRDAEQKLKNSNQATTAQLKRASDAVQKQSAKHKALVEQYKQEGNQVQKLKVQNDN 207 + L + +L+ + + S ++ A+ AL + ++ + Sbjct: 184 EKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTA 243 Query: 208 LSKSNDKIESSYAKTNTKLKQTEKEFNDLNNTIKNHSANVAKAETAVNKEKAALNNLER 266 S +E+ A + + EK N SA + E +A +LE Sbjct: 244 DSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEH 302 Score = 57.0 bits (137), Expect = 6e-10 Identities = 47/255 (18%), Positives = 95/255 (37%), Gaps = 3/255 (1%) Query: 11 ELKLDHLGVQEGMKGLKRQLGVVNSEMKANLSAFDKSEKSMEKYQARIKGLNDRLKVQKK 70 L+ + ++ L++ L + A+ + E AR L L+ Sbjct: 180 TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 239 Query: 71 MYSQVEDELKQVNANYQKAKSSVKDVEKAYLKLVEANKKEKLALDKSKEALKSSNTELKK 130 + ++K + A ++ ++EKA + + + + + + E Sbjct: 240 FSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKAD 299 Query: 131 AENQYKRTNQRKQDAYQKLKQLRDAEQKLKNSNQATTAQLKRASDAVQKQSAKHKALVEQ 190 E+Q + N +Q + L R+A+++L+ +Q Q K + + Q A E Sbjct: 300 LEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREA 359 Query: 191 YKQEGNQVQKLKVQNDNLSKSNDKIESSYAKTNTKLKQTEKEFNDLN---NTIKNHSANV 247 KQ + QKL+ QN S + + KQ EK + N ++ + + Sbjct: 360 KKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKEL 419 Query: 248 AKAETAVNKEKAALN 262 +++ KEKA L Sbjct: 420 EESKKLTEKEKAELQ 434 Score = 51.2 bits (122), Expect = 4e-08 Identities = 41/261 (15%), Positives = 87/261 (33%), Gaps = 10/261 (3%) Query: 21 EGMKGLKRQLGVVNSEMKANLSAFDKSEKSMEKYQARIKGLNDRLKVQKKMYSQVEDELK 80 EG ++A +A + + +EK + + K + L Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224 Query: 81 QVNANYQKAKSSVKDVEKAYLKLVEANKKEKLALDKSKEALKSSNTELKKAENQYKRTNQ 140 A+ +KA + A ++ + EK AL+ + L+ + + Sbjct: 225 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIK 284 Query: 141 RKQDAYQKLKQLRDAEQKLKNSNQATTAQLKRASDAVQKQSAKHKALVEQYKQEGNQVQK 200 + L+ + L++ +Q A + + K L ++ QK Sbjct: 285 TLEAEKAALEAE---KADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEH-------QK 334 Query: 201 LKVQNDNLSKSNDKIESSYAKTNTKLKQTEKEFNDLNNTIKNHSANVAKAETAVNKEKAA 260 L+ QN S + + KQ E E L K A+ ++ + A Sbjct: 335 LEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREA 394 Query: 261 LNNLERSIDKASSEMKTFNKE 281 +E+++++A+S++ K Sbjct: 395 KKQVEKALEEANSKLAALEKL 415 Score = 35.8 bits (82), Expect = 0.002 Identities = 40/262 (15%), Positives = 92/262 (35%), Gaps = 14/262 (5%) Query: 905 KGVSKETEKALEKYVHYSEENSRIMEKVRLNSGQISEDKAKKLLKIETDL-----SNNLI 959 K LE E +EK + S + K+ +E + + Sbjct: 171 STADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL 230 Query: 960 AEIEKRNKKELEKTQELIDKYSAF--DEQEKQNILTRTKEKNDLRIKKEQELNQKIKELK 1017 + + I A + +Q L + E + + ++ K Sbjct: 231 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 290 Query: 1018 EKALSDGQISENERKEIEK-LENQRRDITVKELSKTEKEQERILVRMQRNRNAYSIDEAS 1076 ++ E++ + + ++ RRD+ +K + E E + Q + S Sbjct: 291 AALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLR 350 Query: 1077 KAIKEAEKARKARKKEVDKQYEDDVIAIKNNVNLSKSEKDKLLAIADQRHKDEVRKAKSK 1136 + + + +A+K + E K E + I+ + +L + A K +V KA + Sbjct: 351 RDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREA------KKQVEKALEE 404 Query: 1137 KDAVVDVVKKQNKDIDKEMDLS 1158 ++ + ++K NK++++ L+ Sbjct: 405 ANSKLAALEKLNKELEESKKLT 426
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 29.2 bits (65), Expect = 0.041 Identities = 25/206 (12%), Positives = 54/206 (26%), Gaps = 16/206 (7%) Query: 197 ANSRISDLENKAQAYSRTFDEQKRYMDEKHEAFKQSVNSGGLVTSGSTSNWQKAKITKDD 256 L +A+ + + F+Q++ + G+ +D Sbjct: 61 QEKNTFQLGGQARERLSLIGNKLDELGHTVMRFEQAIA--ASLCMGAV-----LVAHVND 113 Query: 257 GKIMQITGFDFNNPEQRIGDSTQFIYVSQA--INYPRGASTNGTVEYLVVTSDYKRMTYR 314 G++ ++G N ++R + I + QA I A R+ Sbjct: 114 GELSSLSGTLIPNLDKRTLKTEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTRLVIY 173 Query: 315 PNGTN-------KVFVKRKEVGSWSDWSELALNDYNTPFETVQNAQSKANTAESNAKLYT 367 P+ V G+W + A + + A+ + Sbjct: 174 PDEETPRLAYEVNVRFLTPVPGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAGTSTVG 233 Query: 368 DDKFNKRYSVIFDGTANGVGSTLYLN 393 + + T + YL Sbjct: 234 VGRGVLGDQKYINTTYSSYYGYYYLQ 259
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 116 bits (291), Expect = 2e-30 Identities = 97/414 (23%), Positives = 177/414 (42%), Gaps = 18/414 (4%) Query: 12 NNKLLIGIVLSVITFWLFAQSLVNVVPILEDSFNTDIGTVNIAVSITALFSGMFVVGAGG 71 +N++LI + + L L +P + + FN + N + L + G Sbjct: 12 HNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGK 71 Query: 72 LADKYGRIKLTNIGIILNILGSLLIIIS-NIPLLLIIGRLIQGLSAACIMPATLSIIKSY 130 L+D+ G +L GII+N GS++ + + LLI+ R IQG AA + ++ Y Sbjct: 72 LSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARY 131 Query: 131 YIGKDRQRALSYWSIGSWGGSGVCSFFGGAVATLLGWRWIFILSIIISLIALFLIKGTPE 190 ++R +A G GV GG +A + W ++ ++ +I + FL+K + Sbjct: 132 IPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKK 191 Query: 191 TKSKSISLNKFDIKGLVLLVIMLLSLNILITKGSELGVTSLLFITLLAIAIGSFSLFIVL 250 FDIKG++L+ + ++ + T S I+ L +++ SF +F+ Sbjct: 192 EVRIK---GHFDIKGIILMSVGIVFFMLFTTSYS---------ISFLIVSVLSFLIFVKH 239 Query: 251 EKRATNPLIDFKLFKNKAYTGATASNFLLNG-VAGTLIVANTFVQRGLGYSSLQAGSLSI 309 ++ T+P +D L KN + ++ G VAG + + ++ S+ + GS+ I Sbjct: 240 IRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVII 299 Query: 310 TYLVM-VLIMIRVGEKLLQTLGCKKPMLIGTGVLIVGECLISLTFLPEIFYVICCIIGYL 368 M V+I +G L+ G + IG L V ++ +FL E II Sbjct: 300 FPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVS--FLTASFLLETTSWFMTIIIVF 357 Query: 369 FFGLGLGIYATPSTDTAIANAPLEKVGVAAGIYKMASALGGAFGVALSGAVYAI 422 G GL T + ++ ++ G + S L G+A+ G + +I Sbjct: 358 VLG-GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 47.4 bits (112), Expect = 3e-06 Identities = 50/323 (15%), Positives = 96/323 (29%), Gaps = 9/323 (2%) Query: 2582 TKVRAAQTKIDQAKALLQNKEDNSQLVTSKNNLQSSVNQVPSTAGMTQQSIDN------- 2634 T +A Q L + +E + N L+ + + + D Sbjct: 37 TNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSN 96 Query: 2635 YNAKKREAETEITAAQRVIDNGDATAQQISDEKHRVDNALTALNQAKHDLTADTHALEQA 2694 K R+ + ++ I +A + N TA + L A+ AL Sbjct: 97 AKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAAR 156 Query: 2695 VQQLNRTGTTTGKKPASITAYNNSIRALQSDLTSAKNSANAIIQKPIRTVQEVQSALTNV 2754 L + + +A ++ A ++ L + + ++ + + + + Sbjct: 157 KADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTL 216 Query: 2755 NRVNERLTQAINQLVPLADNSALKTAKTKLDEEINKSVTTDGMTQSSIQAYENAKRAGQT 2814 L L T +I ++ E A Sbjct: 217 EAEKAALAARKADL--EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN 274 Query: 2815 ESTNAQNVINNGDATDQQIAAEKTKVEEKYNSLKQAIAGLTPDLAPLQTAKTQLQNDIDQ 2874 ST I +A + AEK +E + L L DL + AK QL+ + + Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQK 334 Query: 2875 PTSTTGMTSASIAAFNEKLSAAR 2897 ++ AS + L A+R Sbjct: 335 LEEQNKISEASRQSLRRDLDASR 357 Score = 41.6 bits (97), Expect = 2e-04 Identities = 66/380 (17%), Positives = 122/380 (32%), Gaps = 36/380 (9%) Query: 2732 SANAIIQKPIRTVQEVQSALTNVNRVNERLTQAINQLVPLAD-----NSALKTAKTKLDE 2786 + + T+++VQ N L + L N L + E Sbjct: 40 VSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKE 99 Query: 2787 EINKSVTTDGMTQSSIQAYENAKRAGQTESTNAQNVINNGDATDQQIAAEKTKVEEKYNS 2846 ++ K+ + S IQ E K + A N A + + AEK + + Sbjct: 100 KLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKAD 159 Query: 2847 LKQAIAGLTPDLAPLQTAKTQLQNDIDQPTSTTGMTSASIAAFNEKLSAARTKIQEIDRV 2906 L++A+ G L+ + A A + L A + Sbjct: 160 LEKALEGAMNFSTADSAKIKTLEAEKAA-------LEARQAELEKALEGAM------NFS 206 Query: 2907 LASHPDVATIRQNVTAANAAKSALDQARNGLTVDKAPLENAKNQLQHSIDTQTSTTGMTQ 2966 A + T+ A A K+ L++A G L+ + + Sbjct: 207 TADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELE 266 Query: 2967 DSINAYNAKLTAARNKIQQINQVLAGSPTVEQINTNTSTANQAKSDLDHARQALTPDKAP 3026 ++ TA KI+ + + + L+ RQ+L D Sbjct: 267 KALEGAMNFSTADSAKIKTLEA------EKAALEAEKADLEHQSQVLNANRQSLRRDLDA 320 Query: 3027 LQTAKTQLEQSINQPTDTTGMTTASLNAYNQKLQAAR----------QKLTEINQVLNGN 3076 + AK QLE + + ++ AS + + L A+R QKL E N++ Sbjct: 321 SREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEA- 379 Query: 3077 PTVQNINDKVTEANQAKDQL 3096 + Q++ + + +AK Q+ Sbjct: 380 -SRQSLRRDLDASREAKKQV 398 Score = 33.9 bits (77), Expect = 0.037 Identities = 52/379 (13%), Positives = 123/379 (32%), Gaps = 21/379 (5%) Query: 8667 QQQALENQINNATTRGEVAQK-LTEAQALNQAMEALRNSIQDQQQTEAGSKFINEDKPQK 8725 L +++NA + K L+E + Q +EA + ++ + N Sbjct: 86 HNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAM-----NFSTADS 140 Query: 8726 DAYQAAVQNAKDLINQTNNPTLDKAQVEQLTQAVNQAKDNLHGDQKLADDKQHAVTDLNQ 8785 + L + + + A + L ++ + +Q + + Sbjct: 141 AKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALE 200 Query: 8786 LNGLNNPQRQALESQINNAATRGEVAQKLAEAKALDQAMQALRNSIQDQQQTESG--SKF 8843 + A + A + +A + A+ + + + + +T + Sbjct: 201 GAMNFSTADSAKIKTL--EAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 258 Query: 8844 INEDKPQKDAYQAAVQNAKDLINQTGNPTLDKSQVEQLTQAVTTAKDNLHGDQKLARDQQ 8903 + A + A+ + + +K+ +E + L+ +++ R Sbjct: 259 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDL 318 Query: 8904 QAVTTVNALPNLNHAQQQALTDAINAAPTRTEVAQHVQTATELDHAMETLKNKVDQVN-- 8961 A H + + A+ R + + + + E +E K+++ N Sbjct: 319 DASREAKKQLEAEHQKLEEQNKISEAS--RQSLRRDLDASREAKKQLEAEHQKLEEQNKI 376 Query: 8962 ---TDKAQPNYTEASTDKKEAVDQALQAAESITDPTNGSNANKDAVDQVLTKLQEKENEL 9018 + ++ +AS + K+ V++AL+ A S N + KL EKE Sbjct: 377 SEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEES----KKLTEKEKAE 432 Query: 9019 NGNERVAEAKTQAKQTIDQ 9037 + AEAK ++ Q Sbjct: 433 LQAKLEAEAKALKEKLAKQ 451
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 2e-13 Identities = 23/116 (19%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Query: 2 TSLIIAEDQNMLRQAMVQLIKLHGDFEILADTDNGLDAMKLIEEYNPNVVILDIEMPGMT 61 ++++A+D +R + Q + G +++ T N + I + ++V+ D+ MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRAG-YDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLEVLAEIRKKHLNTKVIIVTTFKRPGYFEKAVVNDVDAYVLKERSIEELVKTINK 117 ++L I+K + V++++ KA Y+ K + EL+ I + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 28.7 bits (64), Expect = 0.016 Identities = 11/34 (32%), Positives = 15/34 (44%) Query: 167 IVTIGLAVLGGLWFPINTFPNWLQHVAHVLPSYH 200 +V + L G FP++ P Q A LP H Sbjct: 184 LVITPILFLSGAVFPVDQLPIVFQTAARFLPLSH 217
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 44.6 bits (105), Expect = 2e-07 Identities = 44/274 (16%), Positives = 101/274 (36%), Gaps = 20/274 (7%) Query: 5 KYLTILVISVVILTSCQSSSSQESTKSGEFRIVPTTVALTMTLDKLDLPIVG--KPTSYK 62 + LT + +S ++ + ++ RIV L L + G +Y+ Sbjct: 11 RLLTAMALSPLLWQMNTAHAAAIDPN----RIVALEWLPVELLLALGIVPYGVADTINYR 66 Query: 63 ---TLPNRYKDVPEIGQPMEPNVEAVKKLKPTHVLSVSTIKDEMQPFYKQLNMKGYFYDF 119 + P V ++G EPN+E + ++KP+ ++ + + + +G+ + Sbjct: 67 LWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSD 126 Query: 120 DS--LKGMQKSITQLGDQFNRKAQAKELNDHLNSVKQKIENKAAKQKKHPKVLILMGVPG 177 L +KS+T++ D N ++ A+ + ++ + K+ P +L + P Sbjct: 127 GKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPR 186 Query: 178 SYLVATDKSYIGDLVKIAGGENVIKVKDRQYISSNT---ENLLNINPDIILRLPHGMPEE 234 LV S +++ G N + + + S + L +L H ++ Sbjct: 187 HMLVFGPNSLFQEILDEYGIPNAWQ-GETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKD 245 Query: 235 VKKMFQKEFKQNDIWKHFKAVKNNHVYDLEEVPF 268 + + +W+ V+ + V F Sbjct: 246 MDAL-----MATPLWQAMPFVRAGRFQRVPAVWF 274
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.9 bits (77), Expect = 0.001 Identities = 27/132 (20%), Positives = 44/132 (33%), Gaps = 4/132 (3%) Query: 184 ADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVSTDTT 243 + A+ + P PA P TE + K + + +V + Sbjct: 1015 EEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKS 1074 Query: 244 KDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNET 303 + TQT + AQ+ E + QT + V K+Q+ KVT + Sbjct: 1075 NVKANTQTN---EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTS-QVS 1130 Query: 304 PKQASKAKELPK 315 PKQ P+ Sbjct: 1131 PKQEQSETVQPQ 1142
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.8 bits (82), Expect = 6e-04 Identities = 37/194 (19%), Positives = 71/194 (36%), Gaps = 15/194 (7%) Query: 447 RIVDKEAFTKANTDKSNKKEQQDNSAKKEA---------TPATPSKPTPSPVEKESQKQD 497 + VD T N +++ N+ + PATPS+ T + E Q+ Sbjct: 990 QTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESK 1049 Query: 498 SQKDDNKQLPSVEKENDASSESGKDKTPATKPT------KGEVESSSTTPTKVVSTTQNV 551 + + + + +N ++ K A T E + + TT TK +T + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 552 AKPTTASSKTTKDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSQNNKNTQENKAKSLP 611 K + KT + TS S + + S +Q + T + +Q N Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTE 1169 Query: 612 QTGEESNKDMTLPL 625 Q +E++ ++ P+ Sbjct: 1170 QPAKETSSNVEQPV 1183
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 40.3 bits (94), Expect = 6e-07 Identities = 14/79 (17%), Positives = 38/79 (48%), Gaps = 4/79 (5%) Query: 9 KQSAFTMIEMLVVMMLISIFLLLTMTSKGLSNLRVIDDEA-NIISFITELNYIKSQAIAN 67 +Q FT++EM+++++L+ + + + + S D A + F +L +++ + + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPAS---RDDSAAQTLARFEAQLRFVQQRGLQT 58 Query: 68 QGYINVRFYENSDTIKVIE 86 + V + + V+E Sbjct: 59 GQFFGVSVHPDRWQFLVLE 77
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 46.4 bits (110), Expect = 9e-10 Identities = 19/76 (25%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Query: 3 KFLKKTQAFTLIEMLLVLLIISLLLILIIPNI--AKQTAHIQSTGCNAQVKMVNSQIEAY 60 + K + FTL+E+++V++II +L L++PN+ K+ A Q + + + + ++ Y Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKA--VSDIVALENALDMY 59 Query: 61 ALKHNRNPSSIEDLIA 76 L ++ P++ + L + Sbjct: 60 KLDNHHYPTTNQGLES 75
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 84.1 bits (208), Expect = 4e-20 Identities = 65/347 (18%), Positives = 137/347 (39%), Gaps = 6/347 (1%) Query: 14 KKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKN-KQLGTTILSEISNGAPC 72 +K +LS + L L L+ L ++ + Q + QL + S++ G Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 73 NQIL-SLIGYSDTI-VMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILV 130 + G + + V E G++ VL +Y + ++ R+ + + YP +L Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 131 SIFIAMIIILNLTVIPQFQQLYTSMNIQLSSFQKTLSFFITSLPTIIVVMLIIVSMLAII 190 + IA++ IL V+P+ + + M L + L ++ T ML+ + + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 191 MKLIYNNLNMLNKIN-FVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQSIVDVYINH 249 +++ + ++ LPLI + T L + + + L + + + Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 250 SS-DPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQ 308 S D R L E G L + LE+ F P + + GE+ G+L+ L+ + Sbjct: 301 MSNDYARHRLSLATDAVRE-GVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAAD 359 Query: 309 ILVKQIEDKAIKQTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSI 355 ++ + +P+L + + ++ I L I+ P+ Q+ + Sbjct: 360 NQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 27.5 bits (61), Expect = 0.039 Identities = 20/99 (20%), Positives = 38/99 (38%), Gaps = 11/99 (11%) Query: 82 DFLKDPVKNGADKFKQYGLPIITSKVTPEK-------LNEGSTEIE-GFKFNVLHTPGHS 133 F+ + K + K Y +P++ S + + N I ++ G+ Sbjct: 39 VFISNLRKALPYERKLYDIPLLRSTLPGSQRYALIHLTNYADETISVAIDVTNVYVMGYR 98 Query: 134 PGSLTYVFDEFAVVG--DTLFNNGIGRTDL-YKGDYETL 169 G +Y F+E + +F + + L Y G+YE L Sbjct: 99 AGDTSYFFNEASATEAAKYVFKDAKRKVTLPYSGNYERL 137
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 80.6 bits (199), Expect = 3e-20 Identities = 50/233 (21%), Positives = 102/233 (43%), Gaps = 20/233 (8%) Query: 11 CIFSFLYQFISIEETSFDYLHRRSKCDYCNSSLKWYELMPIISFLLLKGRCRNCRKRISL 70 F ++E ++ + RS C +CN + E +P++S+L L+GRCR C+ IS Sbjct: 49 YRSYFNPDDEGVDEPPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISA 108 Query: 71 THFLGE--TFALIPIVFIKYDFTYVNATLFITTYVFLLIFTMTDITSLMLDCRLIIIYCI 128 + L E T L V + + + T+ L+ T D+ ++L +L + Sbjct: 109 RYPLVELLTALLSVAVAMTLAPGWGTLAALLLTW-VLVALTFIDLDKMLLPDQLTLPLLW 167 Query: 129 VSLSLSMIY------------PVAFIIISMTTHIFYFLF-RAYIGYGDVLLISALSLFFP 175 L +++ ++++ F L + +GYGD L++AL + Sbjct: 168 GGLLFNLLGGFVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLG 227 Query: 176 LQFTIYVILFTFVIAGLVALITMIFK---PIKLLPLVPFIFISFFINSLFYND 225 Q V+L + ++ + + ++ + K +P P++ I+ +I +L + D Sbjct: 228 WQALPIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWI-ALLWGD 279
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.0 bits (98), Expect = 5e-06 Identities = 39/265 (14%), Positives = 94/265 (35%), Gaps = 26/265 (9%) Query: 52 QKADDLKVKEQELSQKFEERKTQLEETVAYTKERVEGFLNKSKNEQAALKAQQAAIKEEA 111 Q++ ++ EQ+ ++ + + +E + K + +++ + Q KE A Sbjct: 1046 QESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT-NEVAQSGSETKETQTTETKETA 1104 Query: 112 SANNLSDTSQEAQEIQEAKREAQAEADKSVAVSNKESKAVALKAQQAAIKEEASANNLSD 171 T ++ ++ + + Q + VS K+ ++ ++ Q +E N+ Sbjct: 1105 -------TVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI-- 1155 Query: 172 TSQEAQEIQEAKKEAQAETDKSAAVSNEEPKAVALKAQQAAIKEEASANNLSDISQEAQE 231 KE Q++T+ +A P + + E + N + + + + Sbjct: 1156 ------------KEPQSQTNTTADTEQ--PAKETSSNVEQPVTESTTVNTGNSVVENPEN 1201 Query: 232 VQEAKKEAQAEKDSDTLTKDASAAKV--EVSKPESQAERLANAAKQKQAKLTPGSKESQL 289 A + +S K+ V E + + LT + + L Sbjct: 1202 TTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVL 1261 Query: 290 TEALFAEKPVAKNDLKEIPQLVTKK 314 ++A + VA N K + Q +++ Sbjct: 1262 SDARAKAQFVALNVGKAVSQHISQL 1286 Score = 38.1 bits (88), Expect = 7e-05 Identities = 57/326 (17%), Positives = 105/326 (32%), Gaps = 40/326 (12%) Query: 129 AKREAQAEADKSVAVSNKESKAVALKAQQAAIKEEASANNLSDTS-QEAQEIQEAKKEAQ 187 KR + +N ++ ++ + I A + A + + A+ Sbjct: 986 EKRNQTVDTTNITTPNNIQADVPSVPSNNEEI---ARVDEAPVPPPAPATPSETTETVAE 1042 Query: 188 AETDKSAAVSNEEPKAVALKAQQAAIKEEASANNLSDISQ-EAQEVQEAKKEAQAEKDSD 246 +S V E A AQ + +EA +N ++ E + KE Q + + Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 247 TLTKDASA-AKVEVSKPESQAERLANAAKQKQAKLTPGSKESQLTEALFAEKPVAKNDLK 305 T T + AKVE K + + ++++P K+ Q +P +ND Sbjct: 1103 TATVEKEEKAKVETEKTQEVP--------KVTSQVSP--KQEQSETVQPQAEPAREND-- 1150 Query: 306 EIPQLVTKKNDVSETETVNIDNKDTVKQKEAKFENGVITRKADEKTTNNTAVDKKSGKQS 365 TVNI + A E K T++ + + Sbjct: 1151 ---------------PTVNIKEPQSQTNTTADTEQP-------AKETSSNVEQPVTESTT 1188 Query: 366 KKTTPSNKRNASKASTNKTSGQKKQHNKKSSQGAKKQSSSSKSTQKNNQTSNKNSKTTNA 425 T S N + T + + ++S S T++ N ++T A Sbjct: 1189 VNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248 Query: 426 KSSNASKTPNAKVEKAKSKIEKRTFN 451 S NA + A++K + N Sbjct: 1249 LCDLTSTNTNAVLSDARAKAQFVALN 1274 Score = 36.6 bits (84), Expect = 2e-04 Identities = 51/332 (15%), Positives = 105/332 (31%), Gaps = 20/332 (6%) Query: 119 TSQEAQEIQEAKREAQAEADKSVAVSNKESKAVALKA-QQAAIKEEASANNLSDTSQEAQ 177 S + + A+ + + A ++ ++ VA + Q++ E+ + T+Q + Sbjct: 1008 PSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNRE 1067 Query: 178 EIQEAKKEAQAETDKSAAVSNEEPKAVALKAQQAAIKEEASANNLSDISQEAQEVQEAKK 237 +EAK +A T + + + + Q KE A + E +E + + Sbjct: 1068 VAKEAKSNVKANTQTNEV---AQSGSETKETQTTETKETA--------TVEKEEKAKVET 1116 Query: 238 EAQAEKDSDTLTKDASAAKVEVSKPESQAERLANAAKQKQAKLTPGSKESQLTEALFAEK 297 E E T + E +P+++ R + + + + + TE E Sbjct: 1117 EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTAD-TEQPAKET 1175 Query: 298 PVAKNDLKEIPQLVTKKNDVSETETVNIDNKDTVKQKEAKFENGVITRKADEKTTNNTAV 357 V N V E N T ++ N R + V Sbjct: 1176 SSNVEQPVTESTTVNTGNSVVEN-PENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNV 1234 Query: 358 DKKSGKQSKKTTPSNKRNASKASTNKTSGQKKQHNKKSSQGAKKQSSSSKSTQKNNQTSN 417 + + + ++T + S + S + ++ + +Q +Q Sbjct: 1235 EPATTSSNDRSTVALCDLTSTNTNAVLS------DARAKAQFVALNVGKAVSQHISQLEM 1288 Query: 418 KNSKTTNAKSSNASKTPNAKVEKAKSKIEKRT 449 N N SN S N + + K T Sbjct: 1289 NNEGQYNVWVSNTSMNKNYSSSQYRRFSSKST 1320 Score = 35.8 bits (82), Expect = 4e-04 Identities = 29/212 (13%), Positives = 73/212 (34%), Gaps = 4/212 (1%) Query: 72 KTQLEETVAYTKERVEGFLNKSKNEQAALKAQQAAIKEEASANNLSDTSQEAQEIQEAKR 131 + EE + V + +E A+ + + + N D ++ + +E + Sbjct: 1011 PSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAK 1070 Query: 132 EAQAEADKSVAVSNK-ESKAVALKAQQAAIKEEASANNLSDTSQEAQEIQEAKKEAQAET 190 EA++ + + +S + + Q KE A+ E ++ QE K + Sbjct: 1071 EAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVS 1130 Query: 191 DKSAAVSNEEPKAVALKAQQAAI---KEEASANNLSDISQEAQEVQEAKKEAQAEKDSDT 247 K +P+A + + + ++ N +D Q A+E ++ E + Sbjct: 1131 PKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVN 1190 Query: 248 LTKDASAAKVEVSKPESQAERLANAAKQKQAK 279 + +Q + ++ + + + Sbjct: 1191 TGNSVVENPENTTPATTQPTVNSESSNKPKNR 1222
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 115 bits (290), Expect = 6e-33 Identities = 60/227 (26%), Positives = 103/227 (45%), Gaps = 26/227 (11%) Query: 30 IQQTAKA-----ENTVKQITNTNVAPYSGVTWMGA--------GTGFVVGNHTIITNKHV 76 ++Q A N QIT+T Y+ VT++ +G VVG T++TNKHV Sbjct: 61 LEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHV 120 Query: 77 TYHM-KVGDEIKAHPNGFY--NNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFK 133 +KA P+ N G + +I Y G+ D+A+V+ + + Sbjct: 121 VDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSP---NEQNKHIG 177 Query: 134 DFTSKFNIA--SEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVSSDAIIQPGS 191 + ++ +E + N+ I+V GYP + M+ES GK+ + G + D G+ Sbjct: 178 EVVKPATMSNNAETQVNQNITVTGYP-GDKPVATMWESKGKITYLKGEAMQYDLSTTGGN 236 Query: 192 SGSPILNSKHEAIGVIYAGNKPSGESTRGFAVYFSPEIKKFIADNLD 238 SGSP+ N K+E IG+ + G AV+ + ++ F+ N++ Sbjct: 237 SGSPVFNEKNEVIGIHWGGVPNEF----NGAVFINENVRNFLKQNIE 279
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 136 bits (344), Expect = 8e-41 Identities = 63/227 (27%), Positives = 107/227 (47%), Gaps = 27/227 (11%) Query: 30 IQQTAKA-----EHNVKLIKNTNVAPYNGVVSIGS--------GTGFIVGKNTIVTNKHV 76 ++Q A ++ I +T Y V I +G +VGK+T++TNKHV Sbjct: 61 LEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHV 120 Query: 77 VAGMEIGAH-IIAHP---NGEYNNGGFYKVKKIVRYSGQEDIAILHVEDKAVHPKNRNFK 132 V H + A P N + G + ++I +YSG+ D+AI+ +N++ Sbjct: 121 VDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPN---EQNKHIG 177 Query: 133 DYTGILKIA--SEAKENERISIVGYPEPYINKFQMYESTGKVLSVKGNMIITDAFVEPGN 190 + ++ +E + N+ I++ GYP M+ES GK+ +KG + D GN Sbjct: 178 EVVKPATMSNNAETQVNQNITVTGYPGDK-PVATMWESKGKITYLKGEAMQYDLSTTGGN 236 Query: 191 SGSAVFNSKYEVVGVHFGGNGPGNKSTKGYGVYFSPEIKKFIADNTD 237 SGS VFN K EV+G+H+GG + V+ + ++ F+ N + Sbjct: 237 SGSPVFNEKNEVIGIHWGGVP----NEFNGAVFINENVRNFLKQNIE 279
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 112 bits (281), Expect = 1e-31 Identities = 58/227 (25%), Positives = 100/227 (44%), Gaps = 26/227 (11%) Query: 30 IQQTAKA-----ENSVKLITNTNVAPYSGVTWMGA--------GTGFVVGNHTIITNKHV 76 ++Q A N IT+T Y+ VT++ +G VVG T++TNKHV Sbjct: 61 LEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHV 120 Query: 77 TYHM-KVGDEIKAHPNGFY--NNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFK 133 +KA P+ N G + +I Y G+ D+A+V+ + + Sbjct: 121 VDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSP---NEQNKHIG 177 Query: 134 DFTSKFNIA--SEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVTSDAVVQPGS 191 + ++ +E + N+ I+V GYP + M+ES GK+ + G + D G+ Sbjct: 178 EVVKPATMSNNAETQVNQNITVTGYP-GDKPVATMWESKGKITYLKGEAMQYDLSTTGGN 236 Query: 192 SGSPILNSKREAIGVMYASDKPTGESTRSFAVYFSPEIKKFIADNLD 238 SGSP+ N K E IG+ + AV+ + ++ F+ N++ Sbjct: 237 SGSPVFNEKNEVIGIHWGGVPNEFNG----AVFINENVRNFLKQNIE 279
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 179 bits (454), Expect = 4e-57 Identities = 63/217 (29%), Positives = 105/217 (48%), Gaps = 23/217 (10%) Query: 37 EKNVTQVKDTNIFPYNGVVSFK--------DATGFVIGKNTIITNKHV-SKDYKVGDRIT 87 + Q+ DT Y V + A+G V+GK+T++TNKHV + + Sbjct: 73 NNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALK 132 Query: 88 AHP---NGDKGNGGIYKIKSISDYPGDEDISVMNIEEQAVERGPKGFNFNENVQAFNFAK 144 A P N D G + + I+ Y G+ D++++ + + E V+ + Sbjct: 133 AFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNK-----HIGEVVKPATMSN 187 Query: 145 DA--KVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDNILNFDAYIEPGNSGSPVLNSNN 202 +A +V+ I V GYP +ES G I +K + +D GNSGSPV N N Sbjct: 188 NAETQVNQNITVTGYPGDK-PVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKN 246 Query: 203 EVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQKHIEQ 239 EVIG+ +GG + +E+NGAV+ +++F++++IE Sbjct: 247 EVIGIHWGG---VPNEFNGAVFINENVRNFLKQNIED 280
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 177 bits (450), Expect = 2e-56 Identities = 64/230 (27%), Positives = 108/230 (46%), Gaps = 29/230 (12%) Query: 29 EVQQTAKA-----ENNVTKVKDTNIFPYTGVVAFKS--------ATGFVVGKNTILTNKH 75 ++Q A N+ ++ DT Y V + A+G VVGK+T+LTNKH Sbjct: 60 PLEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKH 119 Query: 76 V-SKNYKVGDRITAHP---NSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGF 131 V + + A P N D G ++ ++I Y G+ D+++++ + Sbjct: 120 VVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNK----- 174 Query: 132 NFNDNVTPFKYAAGA--KAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTE 189 + + V P + A + + I V GYP K ++ES G + ++G ++ Y T Sbjct: 175 HIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMWESKGKITYLKGEAMQYDLSTT 233 Query: 190 SGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENID 239 GNSGSPV N NE++GIH+ V N+ N V+ ++ F+ +NI+ Sbjct: 234 GGNSGSPVFNEKNEVIGIHWGG-VPNEFNG---AVFINENVRNFLKQNIE 279
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 138 bits (349), Expect = 1e-41 Identities = 66/212 (31%), Positives = 103/212 (48%), Gaps = 18/212 (8%) Query: 36 EKNVKEITDATKEPYNSVVAF--------VGGTGVVVGKNTIVTNKHIAKSNDIFKNRVS 87 + +ITD T Y V +GVVVGK+T++TNKH+ + + + Sbjct: 73 NNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALK 132 Query: 88 AHHS---SKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFADGA-- 142 A S G + + I +Y G+ DLAIV + + + + V ++ A Sbjct: 133 AFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVK-FSPNEQNKHIGEVVKPATMSNNAET 191 Query: 143 KVKDRISVIGYPKGAQTKYKMFESTGTINHISGTFMEFDAYAQPGNSGSPVLNSKHELIG 202 +V I+V GYP G + M+ES G I ++ G M++D GNSGSPV N K+E+IG Sbjct: 192 QVNQNITVTGYP-GDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIG 250 Query: 203 ILYAGSGKDESEKNFGVYFTPQLKEFIQNNIE 234 I + G +E N V+ ++ F++ NIE Sbjct: 251 IHWGGVP---NEFNGAVFINENVRNFLKQNIE 279
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 160 bits (406), Expect = 2e-47 Identities = 83/351 (23%), Positives = 138/351 (39%), Gaps = 73/351 (20%) Query: 110 SRQWDMNKITNNGASYDDLPKHANTKIAIIDTGVMKNHDDLKNNFSTDSKNLVPLNGFRG 169 + I A ++ + K+A++DTG +H DLK + G R Sbjct: 21 EIPRGVEMI-QAPAVWNQT-RGRGVKVAVLDTGCDADHPDLKAR----------IIGGRN 68 Query: 170 TEPEETGDVHDVNDRKGHGTMVSGQTSANG---KLIGVAPNNKFTMYRVFGSKKT-ELLW 225 ++ GD D GHGT V+G +A ++GVAP + +V + + + W Sbjct: 69 FTDDDEGDPEIFKDYNGHGTHVAGTIAATENENGVVGVAPEADLLIIKVLNKQGSGQYDW 128 Query: 226 VSKAIVQAANDGNQVINISVGSYIILDKNDHQTFRKDEKVEYDALQKAINYAKKKKSIVV 285 + + I A +I++S+G + L +A+ A + +V+ Sbjct: 129 IIQGIYYAIEQKVDIISMSLGGP----------------EDVPELHEAVKKAVASQILVM 172 Query: 286 AAAGNDGIDVNDKQKLKLQREYQGNGEVKDVPASMDNVVTVGSTDQKSNLSEFSNFGMNY 345 AAGN+G + + P + V++VG+ + + SEFSN N Sbjct: 173 CAAGNEG-------------DGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNSN-NE 218 Query: 346 TDIAAPGGSFAYLNQFGVDKWMNEGYMHKENILTTANNGRYIYQAGTSLATPKVSGALAL 405 D+ APG E+IL+T G+Y +GTS+ATP V+GALAL Sbjct: 219 VDLVAPG----------------------EDILSTVPGGKYATFSGTSMATPHVAGALAL 256 Query: 406 IIDKYHLEKHPD----KAIELLYQHGTSKNNKPFSRYGHGELDVYKALNVA 452 I + D + L + N P G+G L + ++ Sbjct: 257 IKQLANASFERDLTEPELYAQLIKRTIPLGNSPK-MEGNGLLYLTAVEELS 306
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.9 bits (67), Expect = 0.031 Identities = 19/107 (17%), Positives = 44/107 (41%), Gaps = 6/107 (5%) Query: 398 RNNDEIVINEKDVESLINDNE----IEAFFEYDT-NLAVNIIENDFKFDRPYIVAISIMY 452 R +++++ + + L ++ +FE ++ +++ + IE F I S+ Sbjct: 886 REGNDLIMYKGEGNVLSIGHKNGITFRNWFEKESGDISNHEIEQIFDKSGRIITPDSLKK 945 Query: 453 LFEMFSISNEERMEIVNNYVPTSFKSKDIRPFKNELVTICNPANNFE 499 E + N + + N D+ P NE+ I + A +F+ Sbjct: 946 ALE-YQQRNNKASYVYGNDALAYGSQGDLNPLINEISKIISAAGSFD 991
>GALLIDERMIN#Gallidermin signature. Length = 52 Score = 47.4 bits (112), Expect = 7e-12 Identities = 29/46 (63%), Positives = 34/46 (73%), Gaps = 1/46 (2%) Query: 2 EKVLDLDVQVKANNNSNDSAGDERITSHSLCTPGCAKTGSFNSFCC 47 ++ DLDV+V A SNDS + RI S LCTPGCAKTGSFNS+CC Sbjct: 8 NELFDLDVKVNAKE-SNDSGAEPRIASKFLCTPGCAKTGSFNSYCC 52
>GALLIDERMIN#Gallidermin signature. Length = 52 Score = 38.9 bits (90), Expect = 2e-08 Identities = 23/46 (50%), Positives = 30/46 (65%), Gaps = 1/46 (2%) Query: 2 EKVLDLDVQVKGNNNTNDSAGDERITSHLFCSFGCEKTGSFNSFCC 47 ++ DLDV+V +NDS + RI S C+ GC KTGSFNS+CC Sbjct: 8 NELFDLDVKVNAKE-SNDSGAEPRIASKFLCTPGCAKTGSFNSYCC 52
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 396 bits (1020), Expect = e-141 Identities = 97/329 (29%), Positives = 177/329 (53%), Gaps = 24/329 (7%) Query: 1 MKMKKLVKSSVASSIALLLLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDNDKLNISQ 60 M K++ ++++ S+ L + ++ A+ + I + K T ++K ++Q Sbjct: 1 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 Query: 61 ILTFNFIKDKSYDKDTLVLKAAGNINSGYKKPNPKDYNYSQ-FYWGGKYNVSVSSESNDA 119 + F+F+KDK Y+KD L+LK G I+S N K N+ + W +YN+ + + + Sbjct: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTN-DKY 119 Query: 120 VNVVDYAPKNQNEEFQVQQTLGYSYGGDINISNGLSGGLNGSKSFSETINYKQESYRTTI 179 V++++Y PKN+ E V QTLGY+ GG+ + L G NGS ++S++I+Y Q++Y + + Sbjct: 120 VSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGG--NGSFNYSKSISYTQQNYVSEV 177 Query: 180 DRKTNHKSIGWGVEAHKIMNNGWGPYGRDSYDPTYGNELFLGGRQSSSNAGQNFLPTHQM 239 +++ N KS+ WGV+A+ + ++LF+G + S + F+P ++ Sbjct: 178 EQQ-NSKSVLWGVKANSFAT-------ESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSEL 229 Query: 240 PLLARGNFNPEFISVLSHKQNDTKKSKIKVTYQREMD---------RYTNQWNRLHWVGN 290 P L + FNP FI+ +SH++ + S+ ++TY R MD Y N + H V N Sbjct: 230 PPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHN 289 Query: 291 NYKNQNTVTFTSTYEVDWQNHTVKLIGTD 319 + N+N +T YEV+W+ H +K+ G + Sbjct: 290 AFVNRN---YTVKYEVNWKTHEIKVKGQN 315
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 433 bits (1116), Expect = e-156 Identities = 214/318 (67%), Positives = 256/318 (80%), Gaps = 10/318 (3%) Query: 1 MFKKKMLAATLSVGLIAPLASPIQE-SRANTNIENIGDGA--EVIKRTEDVSSKKWGVTQ 57 M K K+L TLSV L+APLA+P+ E ++A + E+IG G+ E+IKRTED +S KWGVTQ Sbjct: 1 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 Query: 58 NVQFDFVKDKKYNKDALIVKMQGFINSRTSFSDVKGSGYELTKRMIWPFQYNIGLTTKDP 117 N+QFDFVKDKKYNKDALI+KMQGFI+SRT++ + K + + K M WPFQYNIGL T D Sbjct: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNH--VKAMRWPFQYNIGLKTNDK 118 Query: 118 NVSLINYLPKNKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFNYSKTISYTQKSYVSEVD 177 VSLINYLPKNKIE+T+V QTLGYNIGGNFQSAPS+GGNGSFNYSK+ISYTQ++YVSEV+ Sbjct: 119 YVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVE 178 Query: 178 KQNSKSVKWGVKANEFVTPDGKKSAHDRYLFVQSPNGPTGSAREYFAPDNQLPPLVQSGF 237 +QNSKSV WGVKAN F T G+KSA D LFV + R+YF PD++LPPLVQSGF Sbjct: 179 QQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPH-SKDPRDYFVPDSELPPLVQSGF 237 Query: 238 NPSFITTLSHEKGSSDTSEFEISYGRNLDITYA----TLFPRTGIYAERKHNAFVNRNFV 293 NPSFI T+SHEKGSSDTSEFEI+YGRN+D+T+A T + + + R HNAFVNRN+ Sbjct: 238 NPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYT 297 Query: 294 VRYEVNWKTHEIKVKGHN 311 V+YEVNWKTHEIKVKG N Sbjct: 298 VKYEVNWKTHEIKVKGQN 315
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 39.7 bits (92), Expect = 7e-05 Identities = 41/217 (18%), Positives = 79/217 (36%), Gaps = 20/217 (9%) Query: 588 AIEAARESTKEQLRDYVKTSDYKTDKDGIVERLDTA-EAERTTLKGEIKDKVTLNEYQNG 646 A+E A++ + VK + + A +AE TL G+ NE Sbjct: 190 AVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGK------RNELAQA 243 Query: 647 LEEQKQYTD--DQLSDLSNNPEIKASIEQANQEAQEALKSYIDAQDNLKEKESQAYADGK 704 + K+ + +LS +N+P +A + A K + Q + E++ Sbjct: 244 SAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINA 303 Query: 705 ISEEEQRAIQDAQAKLEEAKQNAELKARNAEKKANAYTDNKVKESTDAQR---RTLT-RY 760 + Q+AI N +K N ++++K++ DA +TLT +Y Sbjct: 304 DITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDATVSFYQTLTEKY 363 Query: 761 GSQIIQNGKEI-------KLRTTKEEFNATNRTLSNI 790 G + + +E+ K+ E A + + Sbjct: 364 GEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDVL 400
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.4 bits (81), Expect = 0.002 Identities = 22/145 (15%), Positives = 44/145 (30%), Gaps = 18/145 (12%) Query: 3 ERIKGLSIGLDLDAANLNRSFAEIKRNFKTLNSDLKLTGNNFKYTEKSTDSYQQRIKELD 62 +IK L AA ++ +D E + + R EL+ Sbjct: 211 AKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKT----LEAEKAALEARQAELE 266 Query: 63 GTIIGYKKNVDDLAKQYDKVSQEQGE--------------NSAEAQKLRQEYNKQANELN 108 + G + + + E+ +A Q LR++ + Sbjct: 267 KALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKK 326 Query: 109 YLERELQKTSAEFEEFKKAQVEAQR 133 LE E QK + + + ++ +R Sbjct: 327 QLEAEHQKLEEQNKISEASRQSLRR 351 Score = 32.0 bits (72), Expect = 0.021 Identities = 12/134 (8%), Positives = 33/134 (24%), Gaps = 14/134 (10%) Query: 18 NLNRSFAEIKRNFKTLNSDLKLTGNNFKYTEKSTDSYQQRIKELDGTIIGYKKNVDDLAK 77 L + K + + L + + E ++ ++ + L Sbjct: 89 ELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEA 148 Query: 78 QYDKVSQEQ--------------GENSAEAQKLRQEYNKQANELNYLERELQKTSAEFEE 123 + ++ + +SA+ + L E LE+ L+ Sbjct: 149 EKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTA 208 Query: 124 FKKAQVEAQRMAES 137 + + Sbjct: 209 DSAKIKTLEAEKAA 222
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 165 bits (419), Expect = 1e-50 Identities = 99/343 (28%), Positives = 157/343 (45%), Gaps = 42/343 (12%) Query: 4 KKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSTA 63 K ++ ++LS ++L A N+ Sbjct: 2 LKNKILTTTLSVSLLAPLANPLLENAKAA-----------------------------ND 32 Query: 64 PDDIGKNGKIT--KRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFE 121 +DIGK I KRTE K + QN+QFDF+ D Y+K+ L++K QG I S + Sbjct: 33 TEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYY 92 Query: 122 SHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDST 181 ++K+ + +++P +Y++ + ++ +++ LPKNKI + V T Y+ GG F S Sbjct: 93 NYKKTNHVKAMRWPFQYNIGLKTN-DKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSA 151 Query: 182 KGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFY 241 +G S +YSK+ISY QQNY + + N+ V W V AN K+ D LF Sbjct: 152 PSLGGNGSFNYSKSISYTQQNYVSEVE-QQNSKSVLWGVKANSFATESGQKSAFDSDLFV 210 Query: 242 RNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEK-SNEKTQFEVTYTRNQDIL 300 + +P F P LV+SGFNP F+ +S+EK S++ ++FE+TY RN D+ Sbjct: 211 GYKPHSK--DPRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVT 268 Query: 301 KNR------PGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKV 337 + + + V YEV+WK +KV Sbjct: 269 HAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKV 311
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 60.3 bits (146), Expect = 1e-12 Identities = 48/248 (19%), Positives = 95/248 (38%), Gaps = 21/248 (8%) Query: 48 PKRVAVLTGFYVGDFIKLGIKPIAVSDITK-DSSILKPYL-KGVDYIG---ENDVERVAK 102 P R+ L V + LGI P V+D + +P L V +G E ++E + + Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTE 94 Query: 103 AKPDLIVVDA-MDKNIKKYQKIAPTIPYTYNKYNH-----KEILKEIGKLTNNEDKAKKW 156 KP +V A + + +IAP + ++ ++ L E+ L N + A+ Sbjct: 95 MKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETH 154 Query: 157 IEEWDDKTRKDKKEIQSKIGQATASVFEPDEKQIYIYNSTWGRGLDIVHDAFGMPMTKQY 216 + +++D R K + + D + + ++ + D +G+P Q Sbjct: 155 LAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGP--NSLFQEILDEYGIPNAWQG 212 Query: 217 KDKLQEDKKGYASISKENISKYA-GDYIFLSKPSYGKFD-FEKTHTWQNIEAVKKGHVIS 274 + + G ++S + ++ Y D + + D T WQ + V+ G Sbjct: 213 ----ETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRF-- 266 Query: 275 YKAEDYWF 282 + WF Sbjct: 267 QRVPAVWF 274
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 26.8 bits (59), Expect = 0.026 Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 2/61 (3%) Query: 76 EYMRILAFVIHSEFRKKGYGKRLLADSEEFSKRLNCKAITLNSGNRNERLSAHKLYSDNG 135 Y I + ++RKKG G LL + E++K + + L + + N +SA Y+ + Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDIN--ISACHFYAKHH 145 Query: 136 Y 136 + Sbjct: 146 F 146
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 49.6 bits (118), Expect = 6e-09 Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 5/92 (5%) Query: 111 QNPSPNPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDNPKPNPDPKPDPDKPK-PNPDP 169 + P P +P+P+P+P P+ PK P P PKP P PKP + P D Sbjct: 56 EPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK-PKPKPKPKPVKKVQEQPKRDV 114 Query: 170 KP---DPDKPKPNPNPKPDPNKPNPNPSPDPD 198 KP P P N P + + P Sbjct: 115 KPVESRPASPFENTAPARLTSSTATAATSKPV 146 Score = 46.1 bits (109), Expect = 7e-08 Identities = 32/110 (29%), Positives = 37/110 (33%), Gaps = 8/110 (7%) Query: 98 QNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDNPK-PNPDP 156 + P P P P P+P P+ PK P P KPKP P PKP + P D Sbjct: 56 EPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKP-KPKPKPKPKPVKKVQEQPKRDV 114 Query: 157 KP---DPDKPKPNPDPKPDPDKPKPNPNPKP---DPNKPNPNPSPDPDQP 200 KP P P N P KP + P P P Sbjct: 115 KPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYP 164 Score = 39.2 bits (91), Expect = 1e-05 Identities = 29/115 (25%), Positives = 35/115 (30%), Gaps = 6/115 (5%) Query: 80 NSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPKPDPDKPK- 138 D P P P + +P P +P P PKPKP PKP + Sbjct: 51 TPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK-PKPKPKPKPVKKVQEQ 109 Query: 139 PNPDPKP---DPDNPKPNPDPKPDPDKPKPNPDPKPDPDKPK-PNPNPKPDPNKP 189 P D KP P +P N P KP P + P P Sbjct: 110 PKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYP 164
>PF04647#Accessory gene regulator B Length = 212 Score = 132 bits (335), Expect = 2e-41 Identities = 27/173 (15%), Positives = 68/173 (39%), Gaps = 7/173 (4%) Query: 18 RNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFLFTLITNLTFYLIRRHAHGAH 77 + ++R G++V + ++I++ +A+++ + L+ + RR + GAH Sbjct: 14 DRSDYPFNQEEIRYGIEVFLGTVFQIIIILLVAFVIGLAKEVAFCLLSAAVYRRFSGGAH 73 Query: 78 APSSFWCYVESIILFILLPLVIVNFHINFLIMIILTVISLGVISV--YAPAATKKKPIPV 135 + C + S+++F +L + + ++IL ++++ P + I Sbjct: 74 CEKYYRCTLTSLLVFNVLAYIAHLIDPAYFQLLILIAFITSLLALLFLVPVDNPRNLISN 133 Query: 136 RLIKRKKYYAIIVSLTLFIITLII-----KEPFAQFIQLGIIIEAITLLPIFF 183 ++ + L + I A I LG++ + TL + Sbjct: 134 TEQRKTLKLKTSMVLMVLFGGSIGAYRLYTHQIALAILLGVLWQTFTLTALGH 186
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.7 bits (77), Expect = 5e-04 Identities = 19/135 (14%), Positives = 44/135 (32%), Gaps = 13/135 (9%) Query: 2 KIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQ 61 I + +DD R + + + T N + D D+ Sbjct: 5 TILVADDDAAIRTVLNQAL-------SRAGYDVRITSNAATLWRWIAAG-DGDLVVTDVV 56 Query: 62 LSTDINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKVAAMDFIFK----DDPAELR 117 + D N L I+K P ++ +++ + + A D++ K + + Sbjct: 57 MP-DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115 Query: 118 TRIIDCLETAHTRLQ 132 R + + ++L+ Sbjct: 116 GRALAEPKRRPSKLE 130
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.044 Identities = 24/130 (18%), Positives = 50/130 (38%), Gaps = 12/130 (9%) Query: 13 LLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSD 72 L Y IT I + + S ++ A S SL++ +A ++ +R Sbjct: 365 LTALYPQDVITREIIENE--LRSEIPDSPIEKAAA--RSGSLSISQAVEENMR-----QY 415 Query: 73 LNDLKQSIAQHQTIDLSVEE-QKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDL 131 ++ D + E + +I+ AL + + A +G++ TL K + +L Sbjct: 416 FASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIK--AADLLGLNRNTLRKKIREL 473 Query: 132 ELDLNKYQLS 141 + + + S Sbjct: 474 GVSVYRSSRS 483
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 46.6 bits (110), Expect = 2e-06 Identities = 59/313 (18%), Positives = 104/313 (33%), Gaps = 20/313 (6%) Query: 2139 PQANNNSSVDASTNSPTMDNDVTSKPEVESTNNG---TTDKPVTETDNATPAESTTNN-- 2193 P+ + +TN T +N P V S N + PV ATP+E+T Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 2194 ----NSTTTATNENAPTGSTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQS 2249 S T NE T +TA A ++ + V S + + E++ Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 2250 TNDKVAQPKS--ENKAKAEKDGSDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEEST 2307 T + K+ E + E S E + P A+ N P+ K+ + T Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQT 1162 Query: 2308 TNQTDAGQLKSETNVASNEA-------DKSPSKADTEVSNKPSTSASSEAKEKMTSTNVS 2360 D Q ET+ + + S + + P+T+ + E Sbjct: 1163 NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNR 1222 Query: 2361 QKDDTATADTNDTQKSVGSA-ANNKATQNDGANASPATVSNGSNSANQDMLNVT-NTDDH 2418 + + N + S + A + + + A +S+ A LNV H Sbjct: 1223 HRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQH 1282 Query: 2419 QAKTKSAQQGKVN 2431 ++ + +G+ N Sbjct: 1283 ISQLEMNNEGQYN 1295 Score = 37.4 bits (86), Expect = 0.001 Identities = 46/280 (16%), Positives = 92/280 (32%), Gaps = 6/280 (2%) Query: 929 RKQEIQNSNASTTEEKQAAYTELDTKKQE-ARTNLDAANTNSDVTTAKDNSIAAINQVQ- 986 R Q + +N +T QA + + +E AR + + T ++ A N Q Sbjct: 988 RNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQE 1047 Query: 987 AATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVV-TANADIDNAAAN 1045 + T +K++ A A R+ A EA ++ Q + T + A Sbjct: 1048 SKTVEKNEQDATET-TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATV 1106 Query: 1046 NDVDNAKTTNEATIAAITPDANVKPAAKQAIADKVQAQETAIDGNNGSTTEEKAAAKQQV 1105 + AK E T + V P KQ ++ VQ Q N+ + ++ ++ Sbjct: 1107 EKEEKAKVETEKTQEVPKVTSQVSP--KQEQSETVQPQAEPARENDPTVNIKEPQSQTNT 1164 Query: 1106 QTEKTTADAAIDAAHTNAEVEAAKKAAIAKIEAIQPATTTKDNAKEAIATKANERKTAIA 1165 + + E+ + TT + +N+ K Sbjct: 1165 TADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHR 1224 Query: 1166 QTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQA 1205 ++ + A ++ T A ++ + N+ + A Sbjct: 1225 RSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDA 1264 Score = 36.2 bits (83), Expect = 0.002 Identities = 33/231 (14%), Positives = 66/231 (28%), Gaps = 10/231 (4%) Query: 36 ASAAEQNQPAQNQPAQPADANTQPNANAGAQANPTAQPAAPANQGQPAVQPANQGGQANP 95 E + A + + A T+ + + + QP +PA + Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVN 1154 Query: 96 AGGAAQPNTQPAGQGNQADPNNAAQAQPGNQATPANQAGQ--GNNQATPNNNATPANQTQ 153 A A ++ QP ++T N N + T P ++ Sbjct: 1155 IKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSE 1214 Query: 154 PANAPAA-------AQPAAPVAANAQTQDPNASNTGE-GSINTTLTFDDPAISTDENRQD 205 +N P + P A + D + + S NT D + Sbjct: 1215 SSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALN 1274 Query: 206 PTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALG 256 V+ ++ + N G+ S + + + + + +K LG Sbjct: 1275 VGKAVSQHISQLEMNNEGQYNVWVSNTSMNKNYSSSQYRRFSSKSTQTQLG 1325 Score = 36.2 bits (83), Expect = 0.002 Identities = 57/309 (18%), Positives = 101/309 (32%), Gaps = 12/309 (3%) Query: 1038 DIDNAAANNDVDNAKTTNEATIAAITPDANVKPAAKQAIADKVQAQETAIDGNNGSTTEE 1097 D+ N TTN T I D P+ + IA +V + Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIA-RVDEAPVPPPAPATPSETT 1037 Query: 1098 KAAAKQQVQTEKTTADAAIDAAHTNAEVEAAKKAAIAKIEAIQPATTTKDNAKEAIATKA 1157 + A+ Q KT DA T A+ K A + ++A + E T+ Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 1158 NERKTAIAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTTGENSIDQVT 1217 E K +T + EE A + V + S + Q++ Q + E + + Sbjct: 1098 TETK----ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ--AEPARENDP 1151 Query: 1218 PTVNKKATARNEITAILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAATTNA 1277 K+ ++ TA +E + + E + + N + ATT Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENT--TPATTQP 1209 Query: 1278 QVDEAKANAEAAINAVTPKVVKKQ---AAKDEIDQLQATQTNVINNDQNATTEEKEAAIQ 1334 V+ +N + + + V A D+ ++ + + NA + A Q Sbjct: 1210 TVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQ 1269 Query: 1335 QLATAVTDA 1343 +A V A Sbjct: 1270 FVALNVGKA 1278
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 144 bits (364), Expect = 3e-40 Identities = 98/416 (23%), Positives = 194/416 (46%), Gaps = 14/416 (3%) Query: 7 TTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIP 66 + R N I+ + I +F ++LN+ +LN +LP I + N +++ W+ T FML + Sbjct: 8 SNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTA 67 Query: 67 LTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPN-FGVLMLARVIQAMGAGVLMPLMQFT 125 + L D++ + L L + GS++ + + F +L++AR IQ GA L+ Sbjct: 68 VYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 126 LFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIAILAFVFGL 185 + KE+RG A GL G ++ +GP + G+I W +++++ + + V L Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPFL 185 Query: 186 VSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALILSMVIIYLF 245 + + D + ++ ++G + FT+ I LI+S++ +F Sbjct: 186 MKLLKKEVRIKGHFDIKGIILMSVGIVFFML---------FTTSYSISFLIVSVLSFLIF 236 Query: 246 IRRQFNITNALLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGL 305 ++ +T+ ++ + KN F + + II ++ G ++P +++ LS G Sbjct: 237 VKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGS 296 Query: 306 VIM-PGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVY 364 VI+ PG + I G D+ GP ++ G T L+++ + FL TS+ I++ Sbjct: 297 VIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIV 356 Query: 365 AIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFG 420 + S I+T +SL+ +E G +++NF ++ G A++ L+S Sbjct: 357 FVLGGL-SFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 103 bits (257), Expect = 5e-26 Identities = 91/405 (22%), Positives = 175/405 (43%), Gaps = 14/405 (3%) Query: 9 VIALILIMFMSAIESSIISLALPTIKQDLNA-GNLISLIFTAYFIALVIANPIVGELLSR 67 +I L ++ F S + +++++LP I D N + + TA+ + I + G+L + Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 68 FKIIYVAIAGLLLFSIGSFMCGLS-TNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIP 126 I + + G+++ GS + + + F++LI++R IQG G+ +L +V Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 127 LRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWTFHFPEE 186 R K G++GS+ + +GP +GG I HW + + IP +I II V + ++ Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAH--YIHWSYLLLIP--MITIITVPFLMKLLKK 191 Query: 187 ETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVEKHVSSP 246 E K FD KG+ L V I M + + I++++ + K + V+ P Sbjct: 192 EVRIKGHFDIKGIILMSVGIVFFMLFTTSY-----SISFLIVSVLSFLIFVKHIRKVTDP 246 Query: 247 FLPVVEF-NRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSG-LVIFPLSVAW 304 F+ N + + + + GF +P +++ LS + G ++IFP +++ Sbjct: 247 FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSV 306 Query: 305 ITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKL-PVLIAFVLILAGLSFGYIY 363 I + + + + + T L VS + SF ++ + +++ + Sbjct: 307 IIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTK 366 Query: 364 TKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQ 408 T S IV + MS T L G I+G L +I Sbjct: 367 TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 27.9 bits (62), Expect = 0.020 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 7/55 (12%) Query: 1 MNKAERQNLIITAIQQNKKMTALELAKYC-----NVSKRTILRDIDDLENQGVKI 50 MNK +R I I N+ T EL NV++ T+ RDI +L VK+ Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKEL--HLVKV 53
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 93.2 bits (231), Expect = 2e-24 Identities = 68/255 (26%), Positives = 112/255 (43%), Gaps = 15/255 (5%) Query: 46 LQGYKILVTGGDSAIGRAAAIAYAKEGADV-AINYLPSEEQDAQEVRQVIEESGQKAVLI 104 ++G +TG IG A A A +GA + A++Y P + + +V ++ + A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLE---KVVSSLKAEARHAEAF 62 Query: 105 PGDIRDEQFNYDLVEQAYQQLGGLDNVTLVAGHQQYHDDIHGFTTEAFTETFETNVYPLF 164 P D+RD ++ + +++G +D + VAG + IH + E + TF N +F Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVF 121 Query: 165 WTVQKALEYLKP--GASITTTSSVQGYNPSPILHDYAASKAAIISLTKSFSEELGPKGIR 222 + +Y+ SI T S P + YA+SKAA + TK EL IR Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 223 VNCVAPGPFWSPLQIS-----GGQPQ---SKIPTFGQKTPLGRAGQPVELCGTYVLLASE 274 N V+PG + +Q S G Q + TF PL + +P ++ + L S Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 275 ESSYTTGQVFGVSGG 289 ++ + T V GG Sbjct: 242 QAGHITMHNLCVDGG 256
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 30.4 bits (68), Expect = 0.043 Identities = 34/172 (19%), Positives = 61/172 (35%), Gaps = 29/172 (16%) Query: 646 QHSIDPSVI------FSKFSNYYEFLVRYKKIDTLLTENESKNLVFFSRQIAPGLKRIDS 699 ++S P+++ F + +E R IDTL + ++ G + + Sbjct: 866 RYSATPNLVAINQHDFGTIESVFELANRSNDIDTLYANSGAQ-----------GRDLLQT 914 Query: 700 LVLEELLKNELTYDELKNKMLNEVKDITEDDIDTSLRILDFSFYNAGIEKIYGSPIIERN 759 L+++ + NE+ T I +G++ + S + N Sbjct: 915 LLIDSH-DAGYARTMIDATSANEITKQLNTATTTLNNIASLEHKTSGLQTLSLSNAMILN 973 Query: 760 ERMIRLSDAFTN----------ALSNQTFNMFLEDLIELSKYNNEKYQKGKN 801 R++ LS TN AL +Q F LE E+ KY+K N Sbjct: 974 SRLVNLSRRHTNHIDSFAKRLQALKDQRFAS-LESAAEVLYQFAPKYEKPTN 1024
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 55.0 bits (132), Expect = 2e-10 Identities = 18/66 (27%), Positives = 20/66 (30%) Query: 815 PTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPTEPGKPIPPAKEEPKKPSKPVEQ 874 P V PE P PE PE P + KP P K K +P Sbjct: 54 DLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRD 113 Query: 875 GKVVTP 880 K V Sbjct: 114 VKPVES 119 Score = 48.4 bits (115), Expect = 4e-08 Identities = 24/69 (34%), Positives = 28/69 (40%), Gaps = 2/69 (2%) Query: 805 EEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPTEPGKPIPPAKEE 864 D PP P PE EPE P PE P E P KP+ +E+ Sbjct: 52 PADLEPP--QAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQ 109 Query: 865 PKKPSKPVE 873 PK+ KPVE Sbjct: 110 PKRDVKPVE 118 Score = 45.0 bits (106), Expect = 6e-07 Identities = 28/120 (23%), Positives = 37/120 (30%), Gaps = 6/120 (5%) Query: 821 EVPSEPETPTPPTPEVPSEPETPTPPTPEVPTEPGKPIPPAKEEPKKPSKPVEQGKVVTP 880 EP P PE EPE P PE P E I +PK KP + V Sbjct: 52 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIE----KPKPKPKPKPK-PVKKV 106 Query: 881 VIEINEKVKAVVPTKKAQSKKSELPETGGEESTNNGMLFGGLFSILGLALLRRNKKNHKA 940 + VK V + + + P + G L RN+ + A Sbjct: 107 QEQPKRDVKPVESRPASPFENTA-PARLTSSTATAATSKPVTSVASGPRALSRNQPQYPA 165 Score = 40.7 bits (95), Expect = 1e-05 Identities = 14/88 (15%), Positives = 32/88 (36%) Query: 794 VSGHNEGQQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPTE 853 V+ + + P+V P P +P P+ + +P+ P +V + Sbjct: 50 VTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQ 109 Query: 854 PGKPIPPAKEEPKKPSKPVEQGKVVTPV 881 P + + P + P P + ++ + Sbjct: 110 PKRDVKPVESRPASPFENTAPARLTSST 137 Score = 36.5 bits (84), Expect = 3e-04 Identities = 17/101 (16%), Positives = 27/101 (26%), Gaps = 1/101 (0%) Query: 791 LPQVSGHNEGQQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEV 850 L + + E P P PP + P P+ + P +V Sbjct: 55 LEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDV 114 Query: 851 -PTEPGKPIPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKA 890 P E P P + + PV + +A Sbjct: 115 KPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRA 155
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 55.0 bits (132), Expect = 3e-10 Identities = 21/81 (25%), Positives = 23/81 (28%), Gaps = 4/81 (4%) Query: 882 PTPEVPSE----PETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPAEPGKPVP 937 P P P P V PE P PE PE P + KP P Sbjct: 39 PAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 98 Query: 938 PAKEEPKKPSKPVEQGKVVTP 958 K K +P K V Sbjct: 99 KPKPVKKVQEQPKRDVKPVES 119 Score = 50.0 bits (119), Expect = 1e-08 Identities = 25/73 (34%), Positives = 30/73 (41%), Gaps = 8/73 (10%) Query: 879 PTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPAEPGKPVPP 938 P V PE P PE PE P P V +P+ P P KPV Sbjct: 54 DLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEA-PVVIEKPKPKPKPKP-------KPVKK 105 Query: 939 AKEEPKKPSKPVE 951 +E+PK+ KPVE Sbjct: 106 VQEQPKRDVKPVE 118 Score = 48.1 bits (114), Expect = 5e-08 Identities = 21/102 (20%), Positives = 30/102 (29%), Gaps = 2/102 (1%) Query: 869 EEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEV 928 + PP P P PE PE P + P P V E P V Sbjct: 58 PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPV 117 Query: 929 PAEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVA 970 + P P P + + PV + +A++ Sbjct: 118 ESRPASPF--ENTAPARLTSSTATAATSKPVTSVASGPRALS 157 Score = 46.5 bits (110), Expect = 2e-07 Identities = 16/87 (18%), Positives = 30/87 (34%) Query: 873 TPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPAEP 932 TP + P P P P +P P+ + +P+ P +V +P Sbjct: 51 TPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQP 110 Query: 933 GKPVPPAKEEPKKPSKPVEQGKVVTPV 959 + V P + P P + ++ + Sbjct: 111 KRDVKPVESRPASPFENTAPARLTSST 137 Score = 43.1 bits (101), Expect = 3e-06 Identities = 20/89 (22%), Positives = 24/89 (26%), Gaps = 3/89 (3%) Query: 891 ETPTPPTP-EVPSEPETPTPPTPEVPSEPETPTPPTPEVPAEPGKPVPPA--KEEPKKPS 947 E P P P V P V PE P PE P P E+PK Sbjct: 37 ELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP 96 Query: 948 KPVEQGKVVTPVIEINEKVKAVAPTKKPQ 976 KP + + + P Sbjct: 97 KPKPKPVKKVQEQPKRDVKPVESRPASPF 125 Score = 36.1 bits (83), Expect = 5e-04 Identities = 19/90 (21%), Positives = 26/90 (28%), Gaps = 3/90 (3%) Query: 865 QQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPP 924 + + E P P PP + P P+ + P +V P P Sbjct: 65 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVK--PVESRPA 122 Query: 925 TP-EVPAEPGKPVPPAKEEPKKPSKPVEQG 953 +P E A A KP V G Sbjct: 123 SPFENTAPARLTSSTATAATSKPVTSVASG 152 Score = 33.4 bits (76), Expect = 0.004 Identities = 20/94 (21%), Positives = 26/94 (27%), Gaps = 7/94 (7%) Query: 863 EGQQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETP- 921 E E + P PP + P P V E P V S P +P Sbjct: 66 EPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPF 125 Query: 922 ------TPPTPEVPAEPGKPVPPAKEEPKKPSKP 949 + A KPV P+ S+ Sbjct: 126 ENTAPARLTSSTATAATSKPVTSVASGPRALSRN 159
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 32.4 bits (73), Expect = 0.006 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 4/51 (7%) Query: 122 LKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIVIRKAETIQSPIT 172 LKALL K+ S LNENEK ++TI + +K+ IR + ++ PI+ Sbjct: 418 LKALLE----KEDSAELNENEKKLVETIKKAYTIEKDSSIRWNQLVEKPIS 464
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 334 bits (858), Expect = e-118 Identities = 80/285 (28%), Positives = 157/285 (55%), Gaps = 8/285 (2%) Query: 3 KLIFLIVIALVLS---ACNSNSSHAKELNDLEKKYNAHIGVYALDTKSGKEVK-FNSDKR 58 + I L +I+L+ + A +++ +++ E + + +G+ +D SG+ + + +D+R Sbjct: 2 RYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADER 61 Query: 59 FAYASTSKAINSAILLEQVPYNK--LNKKVHINKDDIVAYSPILEKYVGKDITLKALIEA 116 F ST K + +L +V L +K+H + D+V YSP+ EK++ +T+ L A Sbjct: 62 FPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAA 121 Query: 117 SMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAA 176 ++T SDN+A N ++ +GG + L+++GD VT R+E ELN P +DT+TPA+ Sbjct: 122 AITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPAS 181 Query: 177 FGKTLNKLIANGKLSKENKKFLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQAITYASRN 236 TL KL+ + +LS +++ LL M++++ LI+ +P + +ADK+G A +R Sbjct: 182 MAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTG-AGERGARG 240 Query: 237 DVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF 281 VA + P ++ ++VI+ S ++ I+ ++++ + Sbjct: 241 IVALLGPNNKA-ERIVVIYLRDTPASMAERNQQIAGIGAALIEHW 284
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 34.3 bits (78), Expect = 0.002 Identities = 27/195 (13%), Positives = 56/195 (28%), Gaps = 11/195 (5%) Query: 419 SAIGAGVMNRTQERFNKIRHEQAQNKKAKRENQRDEPAPPLQNDNDLRRRQQDKPMPLFI 478 G MN + K + + +KA E ++ E L+ + K L Sbjct: 161 EKALEGAMNFSTADSAK--IKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEA 218 Query: 479 NKDNQKNGNKRREQQESMNGNDVKSASVESNANNYSKQPQKASQQEHQVRETRQRKDIQR 538 K E+ N + S + + +KA+ + Q + + Sbjct: 219 EKAALAARKADLEKALEGAMNFSTADSAKIKT----LEAEKAALEARQAELEKALEGAMN 274 Query: 539 SPQVVNQPLNNENHSINRKEQKSVQTAYDTDVQKRQIQNATQNQQSRQSGNRNQPITRNS 598 + + E + + Q+ NA + R + + Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLE-----HQSQVLNANRQSLRRDLDASREAKKQLE 329 Query: 599 QSKDRLKEQKDINKH 613 +L+EQ I++ Sbjct: 330 AEHQKLEEQNKISEA 344
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.013 Identities = 9/27 (33%), Positives = 17/27 (62%), Gaps = 1/27 (3%) Query: 454 KGAVSDSPHVLITGQTGKGKSFLAKLL 480 + +D ++ITG++G GK +A+ L Sbjct: 155 RLMQTDLT-LMITGESGTGKELVARAL 180
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 133 bits (336), Expect = 5e-37 Identities = 94/440 (21%), Positives = 180/440 (40%), Gaps = 52/440 (11%) Query: 4 LLQQYEYKIIYKRILYTCFILFIYILGTNISI--VSYNDMQ------VKHESFFKIAISN 55 + + + K++L+T I+ +Y +GT+I I V Y ++Q ++ F + Sbjct: 5 FARAFRTPDLRKKLLFTLAIIVVYRVGTHIPIPGVDYKNVQQCVREASGNQGLFGLVNMF 64 Query: 56 MGGDVNTLNIFTLGLGPWLTSMIILMLISYRNMDKYMKQTSLEKHYKE------------ 103 GG + + IF LG+ P++T+ IIL L++ + LE KE Sbjct: 65 SGGALLQITIFALGIMPYITASIILQLLT-------VVIPRLEALKKEGQAGTAKITQYT 117 Query: 104 RILTLILSVIQSYFVIHEYVSKERVHQDN-------------IYLTILILVTGTMLLVWL 150 R LT+ L+++Q ++ S + + ++ + GT +++WL Sbjct: 118 RYLTVALAILQGTGLVATARSAPLFGRCSVGGQIVPDQSIFTTITMVICMTAGTCVVMWL 177 Query: 151 ADKNSRYGIAGPMPIVMVSIIKSMMHQKMEYI------DASHIVIALLITLVIITLFILL 204 + + GI M I+M I + + I I +I + +I + +++ Sbjct: 178 GELITDRGIGNGMSILMFISIAATFPSALWAIKKQGTLAGGWIEFGTVIAVGLIMVALVV 237 Query: 205 FIELVEVRIPYI----DLMNVSATNMRSYLSWKVNPAGSITLMMSISAFVFLKSGIHFIL 260 F+E + RIP + S +Y+ KVN AG I ++ + S F Sbjct: 238 FVEQAQRRIPVQYAKRMIGRRSYGGTSTYIPLKVNQAGVIPVIFASSLLYIPALVAQFAG 297 Query: 261 SMFNKDVSDDMPMMTFDSPIGISVYLVIQMLLGYFLSRFLINTKQKSKDFLKSGNYFSGV 320 + + D PI I Y ++ + +F N ++ + + K G + G+ Sbjct: 298 GNSGWKSWVEQNLTKGDHPIYIVTYFLLIVFFAFFYVAISFNPEEVADNMKKYGGFIPGI 357 Query: 321 KPGKDTERYLNYQARRVCWFGSALVTVIIGIPLYFTLFVPHLSTEIYFS-VQLIVLVYIS 379 + G+ T YL+Y R+ W GS + +I +P L S F ++++V + Sbjct: 358 RAGRPTAEYLSYVLNRITWPGSLYLGLIALVP-TMALVGFGASQNFPFGGTSILIIVGVG 416 Query: 380 INIAETIRTYLYFDKYKPFL 399 + + I + L Y+ FL Sbjct: 417 LETVKQIESQLQQRNYEGFL 436
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 60.2 bits (145), Expect = 8e-11 Identities = 202/915 (22%), Positives = 360/915 (39%), Gaps = 6/915 (0%) Query: 753 MSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVSTSASTSKSTSVSLSDSVSASKS 812 +D V+ + S + + + +T S S + ++ + S Sbjct: 109 RADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQTIEIATYGSTL 168 Query: 813 LSTSESNSVSSSTSTSLVNSQSVSSSMSGSVSKSTSLSDSISNSSSTEKSESLSTSTSDS 872 T +S ++ ST S + GS + + S ++ ST+ + S+ + Sbjct: 169 SGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQMAGY 228 Query: 873 LRTSTSLSDSVSMSTSGSLSKSQSLSTSTSDSASTSQSVSDSTSNSISTSESLSESASTS 932 T T + S + GS + S+ + ST + DS+ + S ++ S Sbjct: 229 GSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDL 288 Query: 933 DSISISNSIANSQSA------STSKSDSQSTSISLSTSDSKSMSTSESLSDSTSTSDSVS 986 + S A + S+ ST + +ST + S + S+ + ST + Sbjct: 289 TAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGD 348 Query: 987 GSLSIATSQSVSTSSSDSMSTSEMISDSMSTSGSLAASDSKSMSVSSSMSTSQSGSTSES 1046 S IA S T+ DS T+ S + GS + S + + S+ +G S Sbjct: 349 DSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQ 408 Query: 1047 LSDSISTSDSDSKSLSLSTSQSGSTSTSTSTSSSVRTSESQSTSGSMSASQFDSTSISTS 1106 + ST + S + S T+ ST ++ S + GS + DS+ + Sbjct: 409 TAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGY 468 Query: 1107 FSDSTSDSKSASTASSESISQSVSTSTSGSVSTSTSLSTSNSERTSTSMSDSTSLSTSES 1166 S T+ S TA S S + S+ + ST + S T+ S T+ + S+ Sbjct: 469 GSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDL 528 Query: 1167 DSTSDSTSTSDSISEAISGSESTSISLSESNSTSDSESKSASAFLSESLSESTSESTSES 1226 + STST+ + S I+G ST + S T+ S + S+ + S T+ S Sbjct: 529 ITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGS 588 Query: 1227 LSGSTSDSTSLSDSNSESGSTSTSLSNSTSSSTSISTSISGSASTSAYKSDSVSTSLSTS 1286 S + S ++ S T+ S T+ S+ T+ GS ST+ S ++ ST Sbjct: 589 DSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQ 648 Query: 1287 TSTSLSDSTSLSTSLSDSASGSKSNSLSASMSTSDSISTRKSESLSTSTSLSVSTSESES 1346 T+ S T+ S + GS + S ST+ + S+ + ST T+ S + Sbjct: 649 TAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGY 708 Query: 1347 GSTSSSESKSDSTSMSLSMSQSISGSTSVSTSESLSDSTSTSLSLSASMNQSGVDSNSAS 1406 GST +++ SD TS S S + + S+ ++ S ++ S + + S Sbjct: 709 GSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQTAREQSVL 768 Query: 1407 QSASTSTSTSTSESDSQSTSSYTSQSTSQSESTSTSTSLSDSTSMSRSTSQSGSTSTSAS 1466 + STST+ ++S + T + S T+ S + S T+ GSTST+ + Sbjct: 769 TTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGYGSTSTAGA 828 Query: 1467 LSASESESDSQSISTSASDSTSESTSTSLSDSTSTSNSTSESTSKAISTSASASESDSSS 1526 S+ + S + S T+ ST + S + STS A S+ + S+ Sbjct: 829 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSLIAGYGSTQ 888 Query: 1527 TSLSDSTSASMQSSESDSQSTSASLSNSQSTSTSNRMSTITSESVSESTSESGSTSESTS 1586 T+ +S + S +Q S + STST+ S++ + S T+ ST + Sbjct: 889 TAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTLMAGY 948 Query: 1587 ESDSTSISDSESVSTSTSMSLSTSDSTSTSESLSTSMSGSQSISDSTSTSMSNSTSMSNS 1646 S T+ S + S S++ DS+ + ST +G QS + S + S Sbjct: 949 GSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEHSSTL 1008 Query: 1647 TSTSMSGSTSTSESN 1661 T+ S +T+ ++S+ Sbjct: 1009 TAGYGSTATAGADSS 1023 Score = 57.1 bits (137), Expect = 6e-10 Identities = 215/966 (22%), Positives = 378/966 (39%), Gaps = 26/966 (2%) Query: 687 ATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTITIVSTDASGNKTTTTFKY 746 + + +T + S T+ +TI ST + T+ Sbjct: 107 HHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQTIEIATYGS 166 Query: 747 EVTRNSMSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVSTSASTSKSTSVSLSDS 806 ++ S ++ GST+ + ST A S T+ + S +V+ ST + S + Sbjct: 167 TLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQMA 226 Query: 807 VSASKSLSTSESNSVSSSTSTSLVNSQSVSSSMSGSVSKSTSLSDSISNSSSTEKSESLS 866 S S+ + ST S + GS + S + ST+ ++ S Sbjct: 227 GYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGS 286 Query: 867 TSTSDSLRTSTSLSDSVSMSTSGSLSKSQSLSTSTSDSASTSQSVSDSTSNSISTSESLS 926 T+ T T+ +DS ++ GS + ST T+ ST + S+ + S Sbjct: 287 DLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQ--TAQKGSDLTAGYGSTG 344 Query: 927 ESASTSDSISISNSIANSQSASTSKSDSQSTSISLSTSDSKSMSTSESLSDSTSTSDSVS 986 + S I+ S + S+ + ST + SD + S + + S+ + Sbjct: 345 TAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGY 404 Query: 987 GSLSIATSQSVSTSSSDSMSTSEMISDSMSTSGSLAASDSKSMSVSSSMSTSQSGSTSES 1046 GS A +S T+ S T++ SD + GS + S ++ ST +G S Sbjct: 405 GSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSL 464 Query: 1047 LSDSISTSDSDSKSLSLSTSQSGSTSTSTSTSSSVRTSESQSTSGSMSASQFDSTSISTS 1106 + ST + S + S ST+ S+ + S + GS + + ST + + Sbjct: 465 TAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQN 524 Query: 1107 FSDSTSDSKSASTASSESISQSVSTSTSGSVSTSTSLSTSNSERTSTSMSDSTSLSTSES 1166 SD + S STA + S + ST + S + S +T+ SD T+ S Sbjct: 525 ESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTG 584 Query: 1167 DSTSDSTSTSDSISEAISGSESTSISLSESNSTSDSESKSASAFLSESLSESTSESTSES 1226 + SDS+ + S + S+ + S T+ +S + + S S + + S + Sbjct: 585 TAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGY 644 Query: 1227 LSGSTSDSTSL------SDSNSESGSTSTSLSNSTSSSTSISTSISGSASTSAYKSDSVS 1280 S T+ S+ S ++ GS T+ STS++ + S+ I+G ST +S+ Sbjct: 645 GSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSIL 704 Query: 1281 TSLSTSTSTSLSDSTSLSTSLSDSASGSKSNSLSASMSTSDSISTRKSESLSTSTSLSVS 1340 T+ ST T+ S S S S +G+ S+ ++ ST + + ST + Sbjct: 705 TAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQTARE 764 Query: 1341 TSESESGSTSSSESKSDSTSMSLSMSQSISGSTSVSTSESLSDSTSTSLSLSASMNQSGV 1400 S +G S+S + +DS+ ++ S +G S+ T+ S T+ S + S Sbjct: 765 QSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGYGSTS 824 Query: 1401 DSNSASQSASTSTSTSTSESDSQSTSSYTSQSTSQSESTSTSTSLSDSTSMSRS------ 1454 + + S + ST T+ +S T+ Y S T+Q S T+ S ST+ S Sbjct: 825 TAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSLIAGY 884 Query: 1455 ------------TSQSGSTSTSASLSASESESDSQSISTSASDSTSESTSTSLSDSTSTS 1502 T+ GST T+ S + S S + S + ST + ST Sbjct: 885 GSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTL 944 Query: 1503 NSTSESTSKAISTSASASESDSSSTSLSDSTSASMQSSESDSQSTSASLSNSQSTSTSNR 1562 + S+ A S+ + S+S + DS+ + S + S + ST T+ Sbjct: 945 MAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEH 1004 Query: 1563 MSTITSESVSESTSESGSTSESTSESDSTSISDSESVSTSTSMSLSTSDSTSTSESLSTS 1622 ST+T+ S +T+ + S+ + S TS S + S +S S T+ S+ Sbjct: 1005 SSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVLTAGYGSSL 1064 Query: 1623 MSGSQS 1628 +SG +S Sbjct: 1065 ISGRRS 1070 Score = 53.2 bits (127), Expect = 9e-09 Identities = 205/901 (22%), Positives = 362/901 (40%), Gaps = 8/901 (0%) Query: 732 STDASGNKTTTTFKYEVTRNSMSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVST 791 ST +G ++ T Y T+ + S T+G + + S + ST T+G T Sbjct: 262 STQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQT 321 Query: 792 SASTSKSTSVSLSDSVSASKSLSTSESNS--VSSSTSTSLVNSQSVSSSMSGSVSKSTSL 849 + S T+ SD + S T+ +S ++ ST S ++ GS + Sbjct: 322 AGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKG 381 Query: 850 SDSISNSSSTEKSESLSTSTSDSLRTSTSLSDSVSMSTSGSLSKSQSLSTSTSDSASTSQ 909 SD + ST + + S+ + T T+ +S + GS +Q S T+ ST Sbjct: 382 SDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGT 441 Query: 910 SVSDSTSNSISTSESLSESASTSDSISISNSIANSQSASTSKSDSQSTSISLSTSDSKSM 969 + DS+ + S + S+ + S A S T+ S ST+ S+ + Sbjct: 442 AGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYG 501 Query: 970 STSESLSDSTSTSDSVSGSLSIATSQSVSTSSSDSMSTSEMISDSMSTSGSLAASDSKSM 1029 ST + ST T+ S + S ++ S S + + + S A+ +S Sbjct: 502 STQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLT 561 Query: 1030 SVSSSMSTSQSGSTSESLSDSISTSDSDSKSLSLSTSQSGSTSTSTSTSSSVRTSESQST 1089 + S T++ GS + S T+ SDS ++ GST T++ SS S T Sbjct: 562 AGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIA----GYGSTQTASYHSSLTAGYGSTQT 617 Query: 1090 SGSMSASQFDSTSISTSFSDSTSDSKSASTASSESISQSVSTSTSGSVSTSTSLSTSNSE 1149 + S S ST+ +DS+ + ST ++ S + S + S T+ Sbjct: 618 AREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYG 677 Query: 1150 RTSTSMSDSTSLSTSESDSTSDSTSTSDSISEAISGSESTSISLSESNSTSDSESKSASA 1209 TST+ +DS+ ++ S T+ S + + ++ S S STS + + S+ Sbjct: 678 STSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLI 737 Query: 1210 FLSESLSESTSESTSESLSGSTSDSTSLSDSNSESGSTSTSLSNSTSSSTSISTSISGSA 1269 S ++ S+ + GST + S + GSTST+ ++S+ + ST +G Sbjct: 738 AGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYH 797 Query: 1270 STSAYKSDSVSTSLSTSTSTSLSDSTSLSTSLSDSASGSKSNSLSASMSTSDSISTRKSE 1329 S S T+ S T+ STS + + S +G S + S + Sbjct: 798 SILTAGYGSTQTAQERSDLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQT 857 Query: 1330 SLSTSTSLSVSTSESESGSTSSSESKSDSTSMSLSMSQSISGSTSVSTSESLSDSTSTSL 1389 + S + S S +G SS + ST + S +G S T++ SD T+ Sbjct: 858 AQENSDLTTGYGSTSTAGYDSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYG 917 Query: 1390 SLSASMNQSGVDSNSASQSASTSTSTSTSESDSQSTSSYTSQSTSQSESTSTSTSLSDST 1449 S S + +S + + S ++ ST + S T+ S T+ STS + S Sbjct: 918 STSTAGYESSLIAGYGSTQTASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLI 977 Query: 1450 SM--SRSTSQSGSTSTSASLSASESESDSQSISTSASDSTSESTSTSLSDSTSTSNSTSE 1507 + S T+ ST T+ S +E S + S +T+ + S+ ++ S+ S Sbjct: 978 AGYGSTQTAGYQSTLTAGYGSTQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIR 1037 Query: 1508 STSKAISTSASASESDSSSTSLSDSTSASMQSSESDSQSTSASLSNSQSTSTSNRMSTIT 1567 S A S S S T+ S+ S + S + S +++ +S+ + ST Sbjct: 1038 SFLTAGYGSTLISGLRSVLTAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQI 1097 Query: 1568 SESVSESTSESGSTSESTSESDSTSISDSESVSTSTSMSLSTSDSTSTSESLSTSMSGSQ 1627 + + S + GS+ + S S +DS ++ ++ +DST T+ S ++G+ Sbjct: 1098 TGNRSMLIAGKGSSQTAGYRSTLISGADSVQMAGERGKLIAGADSTQTAGDRSKLLAGNN 1157 Query: 1628 S 1628 S Sbjct: 1158 S 1158 Score = 45.5 bits (107), Expect = 2e-06 Identities = 138/631 (21%), Positives = 242/631 (38%), Gaps = 8/631 (1%) Query: 1105 TSFSDSTSDSKSASTASSESISQSVSTSTSGSVSTSTSLSTSNSERTSTSMSDSTSLSTS 1164 TS ++ A +E + S + V + +T S ST + + Sbjct: 99 TSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQT 158 Query: 1165 ESDSTSDSTSTSDSISEAISGSESTSISLSESNSTSDSESKSASAFLSESLSESTSESTS 1224 +T ST + S+ I+G ST + S + S + S ++ S T+ Sbjct: 159 IEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTA 218 Query: 1225 ESLSGSTSDSTSLSDSNSESGSTSTSLSNSTSSSTSISTSISGSASTSAYKSDSVSTSLS 1284 S + S GS T+ ST ++ S+ I+G ST DS T+ Sbjct: 219 GEESSQMAGYGS--TQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGY 276 Query: 1285 TSTSTSLSDSTSLSTSLSDSASGSKSNSLSASMSTSDSISTRKSESLSTSTSLSVSTSES 1344 ST T+ S + S +G+ S+ ++ ST + + ST + S+ Sbjct: 277 GSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDL 336 Query: 1345 ESGSTSSSESKSDSTSMSLSMSQSISGSTSVSTSESLSDSTSTSLSLSASMNQSGVDSNS 1404 +G S+ + DS+ ++ S +G S T+ S T+ S + S + + Sbjct: 337 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGA 396 Query: 1405 ASQSASTSTSTSTSESDSQSTSSYTSQSTSQSESTSTSTSLSDSTSMSRSTSQSGSTSTS 1464 S + ST T+ +S T+ Y S T+Q S T+ S T+ S+ +G ST Sbjct: 397 DSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQ 456 Query: 1465 ASLSASESESDSQSISTSASDSTSESTSTSLSDSTSTSNSTSESTSKAISTSASASESDS 1524 + DS + S T++ S + STS + ES+ A S + S Sbjct: 457 TA------GEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGS 510 Query: 1525 SSTSLSDSTSASMQSSESDSQSTSASLSNSQSTSTSNRMSTITSESVSESTSESGSTSES 1584 + T+ ST + S+ + S S + + S+ + ST T+ S T+ GST + Sbjct: 511 TLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTA 570 Query: 1585 TSESDSTSISDSESVSTSTSMSLSTSDSTSTSESLSTSMSGSQSISDSTSTSMSNSTSMS 1644 SD T+ S + S S ++ ST T+ S+ +G S + S+ + S Sbjct: 571 REGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGS 630 Query: 1645 NSTSTSMSGSTSTSESNSMHPSDSMSMHHTHSTSTSRSSSEATTSTSESQSTLSATSEVT 1704 ST+ + S + S +S+ ST T++ S+ T + + + +S + Sbjct: 631 TSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIA 690 Query: 1705 KHNGTPAQSEKRLPDTGDSIKQNGLLGGVMT 1735 + T + G Q G +T Sbjct: 691 GYGSTQTAGYNSILTAGYGSTQTAQEGSDLT 721 Score = 43.2 bits (101), Expect = 1e-05 Identities = 189/866 (21%), Positives = 333/866 (38%), Gaps = 16/866 (1%) Query: 732 STDASGNKTTTTFKYEVTRNSMSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVST 791 ST +G+ ++ Y T+ + DS T+G + S + ST T+G+ Sbjct: 342 STGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLI 401 Query: 792 SASTSKSTSVSLSDSVSASKSLSTSESNSVSSSTSTSLVNSQSVSSSMSGSVSKSTSLSD 851 + S T+ S + S T++ S ++ S + SS ++G S T+ D Sbjct: 402 AGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGED 461 Query: 852 SISNSSSTEKSESLSTSTSDSLRTSTSLSDSVSMSTSGSLSKSQSLSTSTSDSASTSQSV 911 S + + S + STS + S +G S + ST + S Sbjct: 462 SSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQT 521 Query: 912 SDSTSNSISTSESLSESASTSDSISISNSIANSQSASTSKSDSQSTSISLSTSDSKSMST 971 + + S+ I+ S S + + S I+ S + S + ST + SD + Sbjct: 522 AQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYG 581 Query: 972 SESLSDSTSTSDSVSGSLSIATSQSVSTSSSDSMSTSEMISDSMSTSGSLAASDSKSMSV 1031 S + S S+ + GS A+ S T+ S T+ S + GS + + + S + Sbjct: 582 STGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLI 641 Query: 1032 SSSMSTSQSGSTSESLSDSISTSDSDSKSLSLSTSQSGSTSTSTSTSSSVRTSESQSTSG 1091 + ST +G S + ST + S + S ST+ + S+ + S + Sbjct: 642 AGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYN 701 Query: 1092 SMSASQFDSTSISTSFSDSTSDSKSASTASSESISQSVSTSTSGSVSTSTSLSTSNSERT 1151 S+ + + ST + SD TS S STA ++S + ST + S+ + S +T Sbjct: 702 SILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQT 761 Query: 1152 STSMSDSTSLSTSESDSTSDSTSTSDSISEAISGSESTSISLSESNSTSDSESKSASAFL 1211 + S T+ S S + +DS+ + S +G S + S T+ S + + Sbjct: 762 AREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGYG 821 Query: 1212 SESLSESTS--------------ESTSESLSGSTSDSTSLSDSNSESGSTSTSLSNSTSS 1257 S S + + S S + GST + SD + GSTST+ +S+ Sbjct: 822 STSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSLI 881 Query: 1258 STSISTSISGSASTSAYKSDSVSTSLSTSTSTSLSDSTSLSTSLSDSASGSKSNSLSASM 1317 + ST +G S S T+ S T+ STS + S +G S ++ Sbjct: 882 AGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFK 941 Query: 1318 STSDSISTRKSESLSTSTSLSVSTSESESGSTSSSESKSDSTSMSLSMSQSISGSTSVST 1377 ST + + S+ + S S +G SS + ST + S +G S T Sbjct: 942 STLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQT 1001 Query: 1378 SESLSDSTSTSLSLSASMNQSGVDSNSASQSASTSTSTSTSESDSQSTSSYTSQSTSQSE 1437 +E S T+ S + + S + + S S S T+ S S S T+ Sbjct: 1002 AEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVLTAGYG 1061 Query: 1438 STSTSTSLSDSTS--MSRSTSQSGSTSTSASLSASESESDSQSISTSASDSTSESTSTSL 1495 S+ S S T+ S + S+ + S + + S I+ S T+ ST + Sbjct: 1062 SSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGYRSTLI 1121 Query: 1496 SDSTSTSNSTSESTSKAISTSASASESDSSSTSLSDSTSASMQSSESDSQSTSASLSNSQ 1555 S + S + A + S + S + ++S + S+ + + ++ + Sbjct: 1122 SGADSVQMAGERGKLIAGADSTQTAGDRSKLLAGNNSYLTAGDRSKLTAGNDCILMAGDR 1181 Query: 1556 STSTSNRMSTITSESVSESTSESGST 1581 S T+ S +T+ S+ +GST Sbjct: 1182 SKLTAGINSILTAGCRSKLIGSNGST 1207
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 125 bits (315), Expect = 1e-33 Identities = 91/411 (22%), Positives = 181/411 (44%), Gaps = 14/411 (3%) Query: 13 QRNRVIAVVMIGAFVGVLNQTLMTTILPEIMKDFTVSSSTAQWLTTIFMLVNGIMIPITA 72 + N+++ + I +F VLN+ ++ LP+I DF ++ W+ T FML I + Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 73 FLIERFTLRSLFFNATCFLMIGSFICMLGIN-FPMLLLGRSIQALGAGILMPLTQTLLFI 131 L ++ ++ L GS I +G + F +L++ R IQ GA L ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 132 MFPPEKRGMAMGMFGLVIGFAPAIGPTAAGWFVNIFDWRYLFLVVLLIGMIDFVFGYLSL 191 P E RG A G+ G ++ +GP G + W YL L+ ++ I V + L Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMI--TIITVPFLMKL 188 Query: 192 PNITELSKPNLDKLSVILSTVSFGGLLYGFSTAGNLGWSHPMVNITIIAAIVILTVFIFR 251 K + D +IL +V + ++ S +I +++ +F+ Sbjct: 189 LKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSY---SISF------LIVSVLSFLIFVKH 239 Query: 252 QLKLESPLLEFRVFKYNDFSVAMILIVLMFMLFIGNLTILPIYMQTMMKWSPLESG-LIL 310 K+ P ++ + K F + ++ ++F G ++++P M+ + + S E G +I+ Sbjct: 240 IRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVII 299 Query: 311 LPGGLIMGLLSPVTGKLFDKIGGRILSIMGMLTIMIGALLMAQFSQNTTQLYVIISFSVT 370 PG + + + + G L D+ G + +G+ + + L + F TT ++ I Sbjct: 300 FPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTAS-FLLETTSWFMTIIIVFV 358 Query: 371 MLGNAMIMTPMTTQALNALPRQYIAHGTAMNNTIRQVSAAIGTGILVTLMT 421 + G + T ++T ++L +Q G ++ N +S G I+ L++ Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 54.2 bits (130), Expect = 2e-11 Identities = 22/104 (21%), Positives = 43/104 (41%), Gaps = 5/104 (4%) Query: 1 MEKNQRKKRSDAEYNQQIILTTMEDLLEQGEDISTKKMSDIAKISGVGVGTLYRHFESKT 60 M + +++ + Q I+ + +QG ++ + +IAK +GV G +Y HF+ K+ Sbjct: 1 MARKTKQEAQETR--QHILDVALRLFSQQGVSSTS--LGEIAKAAGVTRGAIYWHFKDKS 56 Query: 61 LLCQAIMDKKVDQMFIEIEDILAENTQWPVRDKINVILTKYLDL 104 L I + + E+E + IL L+ Sbjct: 57 DLFSEIWELSESNI-GELELEYQAKFPGDPLSVLREILIHVLES 99
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.8 bits (77), Expect = 1e-04 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 3/82 (3%) Query: 41 CIVAYKNNDIVGLLTY-KVYDEY--IEIISLDSFVENKGIGSHLLNYAEIIASDMSKRSI 97 + Y N+ +G + ++ Y IE I++ KG+G+ LL+ A A + + Sbjct: 67 AFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGL 126 Query: 98 SVITTNENIKALYFYQKNKYRI 119 + T + NI A +FY K+ + I Sbjct: 127 MLETQDINISACHFYAKHHFII 148
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 25.8 bits (56), Expect = 0.036 Identities = 12/39 (30%), Positives = 24/39 (61%) Query: 8 NDLFLNHVNSNAVKTRKMMGEYIVYYDGVVIGGLYDNRL 46 +++F N V ++ ++ K + Y + D ++ GG YDN+L Sbjct: 56 SEVFANRVITDDIELLKKILAYFLPEDAILKGGHYDNQL 94
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 42.7 bits (100), Expect = 6e-06 Identities = 23/159 (14%), Positives = 55/159 (34%), Gaps = 2/159 (1%) Query: 492 KEESIRAYDVYKNCESYSKVEHELNSKKMNVKEKLNHLEIQISCDNKEIEDLDDRINYNT 551 + ++ V + + + + L K ++ L+ +E+ + +++ N Sbjct: 46 RSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKND 105 Query: 552 KQLETLNELIKSIRDSNKGFVNKLKAIFNSEEDERYKKHN--AEKQQLLGQQIELEKCKK 609 K L I+ + L+ N + K AEK L ++ +LEK + Sbjct: 106 KSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALE 165 Query: 610 IKNEDLVSKLKEKEKLIKQLTKVQLQLDELNSQLQELEA 648 + + + L + ++ + EL L+ Sbjct: 166 GAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN 204 Score = 30.4 bits (68), Expect = 0.043 Identities = 55/363 (15%), Positives = 115/363 (31%), Gaps = 40/363 (11%) Query: 318 HLVVERGKELAKLNNPKDAFVKTKTHETDDKYVYLLKESIAKYKMVVASSNNGAVENISK 377 + + + +L+ N T E + L K + + +S +E Sbjct: 67 NTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSE---KASKIQELEARKA 123 Query: 378 DLPKIEEIIRNPEKCKFPKYEQNYANLAHELKDFAEIAEDLIGESAWGLFSGVFGKSTNI 437 DL K E N L E A DL ++ G + S I Sbjct: 124 DLEKALEGAMNFST----ADSAKIKTLEAEKAALAARKADL-EKALEGAMNFSTADSAKI 178 Query: 438 NQVLSHMLKQDANDIGFAKLLQN-ENNRMSYNELMSEWQSHQRAFLEELRHVEMLKEESI 496 + + +A K L+ N + + + ++ + A +E E ++ Sbjct: 179 KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAM 238 Query: 497 RAYDVY-KNCESYSKVEHELNSKKMNVKEKLNHLEIQISCDNKEIEDLDDRINYNTKQLE 555 ++ + L +++ +++ L + D+ +I+ L+ + Sbjct: 239 NFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKA 298 Query: 556 TLNELIKSIRDSNKGFVNKLKA--------------------IFNSEEDERYKKHNA--- 592 L + + + + L A I + + +A Sbjct: 299 DLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASRE 358 Query: 593 EKQQLLGQQIELEKCKKIK-------NEDLVSKLKEKEKLIKQLTKVQLQLDELNSQLQE 645 K+QL + +LE+ KI DL + + K+++ K L + +L L +E Sbjct: 359 AKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKE 418 Query: 646 LEA 648 LE Sbjct: 419 LEE 421
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 86.4 bits (214), Expect = 2e-20 Identities = 53/305 (17%), Positives = 106/305 (34%), Gaps = 56/305 (18%) Query: 283 TILVTGAGGSIGSEICRQVCNFYPERIILLGHGE------NSIYLIN-RELRNRFGKNVD 335 LVTGA G IG + +R++ GH N Y ++ ++ R Sbjct: 2 KYLVTGAAGFIGFHVS--------KRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPG 53 Query: 336 IVPIIADVQNRARMFEIMEMYKPYAVYHAAAHKHVPLMEDNPEEAVRNNILGTKNTAEAA 395 D+ +R M ++ V+ + V +NP +N+ G N E Sbjct: 54 FQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGC 113 Query: 396 KNAEVKKFVMIST---------------DKAVNPPNVMGASKRIAEMIIQSLNDETHRTN 440 ++ +++ + S+ D +P ++ A+K+ E++ + + + Sbjct: 114 RHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYS-HLYGLP 172 Query: 441 FVAVRFGNVLGSRGS---VIPLFKSQIEEGGPVTV-THPEMTRYFMTI------------ 484 +RF V G G + F + EG + V + +M R F I Sbjct: 173 ATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQD 232 Query: 485 ------PEASRLVLQAGALAEGGEVFVLDMGEPVKIVDLARNLIKLSGKKEDDIRITFTG 538 + + A V+ + PV+++D + L G + + Sbjct: 233 VIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIE---AKKNMLP 289 Query: 539 IRPGE 543 ++PG+ Sbjct: 290 LQPGD 294
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 66.0 bits (161), Expect = 3e-14 Identities = 42/239 (17%), Positives = 82/239 (34%), Gaps = 30/239 (12%) Query: 8 LITGGTGSFGNAVMKWFLDSNIKEIRIFSRDEKKQDDIRKKYNNSKL-----KFYIGDVR 62 L+TG G G V K L++ + + I + ++ D K+ L +F+ D+ Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYY-DVSLKQARLELLAQPGFQFHKIDLA 62 Query: 63 DSQSVETAMRD--VDYVFHAAALKQVPSCEFFPVEAVKTNIIGTENVLQSAIHQNVKKVI 120 D + + + VF + V P +N+ G N+L+ H ++ ++ Sbjct: 63 DREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHLL 122 Query: 121 CLST---------------DKAAYPINAMGISKAMMEKVFVAKSRNIRSEQTLICGTRYG 165 S+ D +P++ +K E + S T G R+ Sbjct: 123 YASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPAT---GLRFF 179 Query: 166 NVMASRGS---VIPLFIDKIKAGEPLTI-TDPDMTRFLMSLEDAVELVVHAFKHAETGD 220 V G + F + G+ + + M R ++D E ++ D Sbjct: 180 TVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHAD 238
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 55.9 bits (135), Expect = 7e-11 Identities = 60/331 (18%), Positives = 101/331 (30%), Gaps = 95/331 (28%) Query: 1 MNIVITGAKGFVGKNLKADLTSTTDHHI------------FEVHRQTKEEELESALLKAD 48 M ++TGA GF+G ++ L + + R + K D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 49 F-----------------VVHL---AGVNRPEHDKEFSLGN-VSYLD-------HVLDIL 80 V V +SL N +Y D ++L+ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAV-------RYSLENPHAYADSNLTGFLNILE-G 112 Query: 81 TRNTKKPAILLSSSIQ----------ATQD------NPYGESKLQGEQLLREYAEEYGNT 124 R+ K +L +SS +T D + Y +K E + Y+ YG Sbjct: 113 CRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLP 172 Query: 125 VYIYRWPNLFGKWCKPNYNSVIATFCYKIARNEEIQV-NNRNVELTLNYVDDIVAEIKRA 183 R+ ++G W +P+ + F + + I V N ++ Y+DDI I R Sbjct: 173 ATGLRFFTVYGPWGRPDM--ALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRL 230 Query: 184 IEGNP------TIENGVPTVP----------NVFKVTLGEIVDLLYKFKQSRLDRTLPKL 227 + P T+E G P N V L + + L + + Sbjct: 231 QDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKK---NM 287 Query: 228 DNLFEKDLYSTY---------LSYLPSTDFS 249 L D+ T + + P T Sbjct: 288 LPLQPGDVLETSADTKALYEVIGFTPETTVK 318
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.4 bits (66), Expect = 0.037 Identities = 17/69 (24%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Query: 179 FVMLFQLALALLFLIIAYASYKKYKENPKIIYVILPLA-IGILNISLIVGERRSYQLYTM 237 L ++ ++FL +A A Y+ + P + +++PL +G+L + + ++ +Y M Sbjct: 872 APALVAISFVVVFLCLA-ALYESWS-IPVSVMLVVPLGIVGVLLAATLFNQKND--VYFM 927 Query: 238 VAVLTVVSL 246 V +LT + L Sbjct: 928 VGLLTTIGL 936
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.6 bits (230), Expect = 5e-24 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 4/125 (3%) Query: 2 TQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGLDKALSHYYDLIILDLMLPSINGL 61 IL+ +D+ + L L+ Y+V + + DL++ D+++P N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EICRKIRQQQS-TPIIIITAKSDTYDKVAGLDYGADDYIVKPFDIEELLARIRAIL---R 117 ++ +I++ + P+++++A++ + + GA DY+ KPFD+ EL+ I L + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 118 RQPQK 122 R+P K Sbjct: 124 RRPSK 128
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 1e-04 Identities = 31/185 (16%), Positives = 68/185 (36%), Gaps = 35/185 (18%) Query: 277 IEEMNRIIKLVEELLELTKGDVNDISSEAQTVHINDE---IRSRIHSLKQLHPD-YQFDT 332 +E+ + +++ L EL + + S A+ V + DE + S + D QF+ Sbjct: 187 LEDPTKAREMLTSLSELMRYSLRY--SNARQVSLADELTVVDSYLQLASIQFEDRLQFEN 244 Query: 333 DLTSKNLEIKMKPHQFEQLFLIFIDNAIKYDVKNKK----IKVKTRLKNKQKIIEITDHG 388 + +++++ P L ++N IK+ + I +K N +E+ + G Sbjct: 245 QINPAIMDVQVPPM----LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG 300 Query: 389 IGIPEEDQDFIFDRFYRVDKSRSRSQGGNGLGLSIAQKIIQL---NGGSIKIKSEINKGT 445 + ++ G GL ++ +Q+ IK+ + K Sbjct: 301 SLALKNTKE------------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN 342 Query: 446 TFKII 450 +I Sbjct: 343 AMVLI 347
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.023 Identities = 21/163 (12%), Positives = 54/163 (33%), Gaps = 11/163 (6%) Query: 46 EVVSEEAGVLSEQLASEGDTVEVGQAIAIIGEGSGNASKENSNDNTPQQNEETNNKKEET 105 E+ E ++ E + EG++V G + + A D Q+ + E+T Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA------DTLKTQSSLLQARLEQT 151 Query: 106 TNNSVDKAEVNQANDENQQRINATPSARRYARENGVNLAEVSPKTNDVVRKEDIDKKQQA 165 + ++ + N + ++ P + + E + L + + + + K+ Sbjct: 152 RYQILSRSI--ELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNL 209 Query: 166 PASTQTTQQASAKEEKKYNQYPTKPVIREKMSRRKKTAAKKLL 208 A+ + N V + ++ K+ + Sbjct: 210 DKKRAERLTVLARINRYENL---SRVEKSRLDDFSSLLHKQAI 249
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.027 Identities = 23/100 (23%), Positives = 39/100 (39%), Gaps = 14/100 (14%) Query: 12 TVFNDAKALFDLNKNILLKGPTGSGKTKLAETL---SEVVDTPMHQVNC---SVDLDTES 65 ++ L + +++ G +G+GK +A L + + P +N DL Sbjct: 148 EIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESE 207 Query: 66 LLGF-KTIKTNAEGQQEIVFVDGPVIKAMKEGHILYIDEI 104 L G K T A+ + F EG L++DEI Sbjct: 208 LFGHEKGAFTGAQTRSTGRF-------EQAEGGTLFLDEI 240
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 26.0 bits (57), Expect = 0.037 Identities = 11/42 (26%), Positives = 23/42 (54%) Query: 10 LRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVS 51 L +NY + S++ ++ N L+ FY + Y + D +N++ Sbjct: 334 LNLNYFCQSFNSIIPDRFSNALKHFYRKQYYTMDYTDNYNIN 375
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 35.6 bits (82), Expect = 3e-04 Identities = 16/79 (20%), Positives = 29/79 (36%), Gaps = 11/79 (13%) Query: 192 VGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEG- 250 GV GV + L + +L + + I Q + VD+IS S G Sbjct: 101 NGVVGVAPEADL--LIIK--------VLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGG 150 Query: 251 SDPAAVMYDAINAAKNKGV 269 + +++A+ A + Sbjct: 151 PEDVPELHEAVKKAVASQI 169
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 54.3 bits (130), Expect = 2e-09 Identities = 53/326 (16%), Positives = 119/326 (36%), Gaps = 23/326 (7%) Query: 170 KYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRV-EPLKEEAAIAKEYKTLSHQMKHSDI 228 K K +E +K+ + E +E L + + E L+ + + Sbjct: 103 KNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLE- 161 Query: 229 VVTVHDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKG-------KRHQLD 281 ++ N + ++ L+ ++A EA + L + ++ K L+ Sbjct: 162 ----KALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLE 217 Query: 282 NDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLMELLENISNEIS 341 + +L + +A E + K A E Q L + LE N + Sbjct: 218 AEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFST 277 Query: 342 EAQDTYKSLKSKQKELNAVIRELEEQLYVSD----------EAHDEKLEEIKNEYYTLMS 391 K+L++++ L A +LE Q V + +A E ++++ E+ L Sbjct: 278 ADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEE 337 Query: 392 EQSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELSA 451 + + L+ ++ + K +L++ ++ EQ K + ++ +++ + + Sbjct: 338 QNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ 397 Query: 452 VDKEIKNIEKDLTDTKKAQNEYEEKL 477 V+K ++ L +K E EE Sbjct: 398 VEKALEEANSKLAALEKLNKELEESK 423 Score = 52.8 bits (126), Expect = 6e-09 Identities = 31/315 (9%), Positives = 94/315 (29%), Gaps = 18/315 (5%) Query: 177 ESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKTLSHQMKHSDIVVTVHDID 236 E +K + + L L ++ +E + + I Sbjct: 57 ERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQ 116 Query: 237 QYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATE 296 + L++ L A + L + ++ L+ +E + Sbjct: 117 ELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSA 176 Query: 297 AFEKYTGQLNVLEERKKNQSETNARYEEEQENLMELLENISNEISEAQDTYKSLKSKQKE 356 + + LE R+ + ++ + E + L+ + Sbjct: 177 KIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEG 236 Query: 357 LNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEAKKSR 416 ++ + + + ++ L N I+ EA+K+ Sbjct: 237 AMNFSTADSAKI----KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA 292 Query: 417 LDSRLVEVFEQLKDIQGQIKTTKK--------------EYQQTNKELSAVDKEIKNIEKD 462 L++ ++ Q + + ++ ++ E+Q+ ++ + +++ +D Sbjct: 293 LEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRD 352 Query: 463 LTDTKKAQNEYEEKL 477 L +++A+ + E + Sbjct: 353 LDASREAKKQLEAEH 367 Score = 33.9 bits (77), Expect = 0.004 Identities = 39/269 (14%), Positives = 89/269 (33%), Gaps = 26/269 (9%) Query: 669 KSKSILSQKDELTTMRHQL----EDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNT 724 K K++ ++K L + L E + + + + K L+ + L E + Sbjct: 142 KIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEG 201 Query: 725 LKEQVHHFEMELDRLTTQETQIKNDHEEFEFEKNDGYT-SDKSRQTLSEKETYLESIKAS 783 ++ L ++ + + E S + E +++A Sbjct: 202 AMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEAR 261 Query: 784 LKRLEDEIERYT-----------KLSKEGKESVTKTQQTLHQKQS----------DLAVV 822 LE +E L E + HQ Q DL Sbjct: 262 QAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDAS 321 Query: 823 KERIKTQQQTIDRLNNQNQQTKHQLKDVKEKIAFFNSDEVMGEQAFQNIKDQINGQQETR 882 +E K + +L QN+ ++ + ++ + + E Q +++Q + +R Sbjct: 322 REAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASR 381 Query: 883 TRLSDELDKLKQQRIELNEQIDAQEAKLQ 911 L +LD ++ + ++ + ++ +KL Sbjct: 382 QSLRRDLDASREAKKQVEKALEEANSKLA 410
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 26.3 bits (58), Expect = 0.012 Identities = 10/42 (23%), Positives = 17/42 (40%), Gaps = 2/42 (4%) Query: 33 GADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINS 74 GA++LD A+ + E P + K+ D F+ Sbjct: 296 GANALDTAKAIKAKLAELQPFFP--QGMKVLYPYDTTPFVQL 335
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 144 bits (365), Expect = 1e-44 Identities = 85/250 (34%), Positives = 136/250 (54%), Gaps = 13/250 (5%) Query: 3 KSALVTGASRGIGRSIALQLAEEGYNV-AVNYAGSKEKAEAVVEEIKAKGVDSFAIQANV 61 K A +TGA++GIG ++A LA +G ++ AV+Y + EK E VV +KA+ + A A+V Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDY--NPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 62 ADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQK 121 D+ + + + + G +D+LVN AG+ R L+ + ++EW+ N GVFN + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 122 ATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVA 181 + M+ +RSG+I+ + S V A Y ++KA + TK ELA I N V+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 182 PGFIVSDMTDAL--SDELKEQML--------TQIPLARFGQDTDIANTVAFLASDKAKYI 231 PG +DM +L + EQ++ T IPL + + +DIA+ V FL S +A +I Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 232 TGQTIHVNGG 241 T + V+GG Sbjct: 247 TMHNLCVDGG 256
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 388 bits (998), Expect = e-138 Identities = 144/311 (46%), Positives = 210/311 (67%), Gaps = 7/311 (2%) Query: 3 KIVVALGGNALGK-----SPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLG 57 ++V+ALGGNAL + S +E ++ V+ TA+ + +I +G+E+VI+HGNGPQVGS+ L Sbjct: 4 RVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLLH 63 Query: 58 LNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDEND 117 ++ PA P GAMSQ +IGY +Q++L+NEL GM+K+VVT++TQ VD+ND Sbjct: 64 MDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKND 123 Query: 118 PAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLI 177 PAF NP+KP+G FY++E A+++ +EKG+I ED+GRG+RRVVPSP P +E E+IK L+ Sbjct: 124 PAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLV 183 Query: 178 KNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYI 237 + +VIA+GGGG+PVI E KG++AVIDKD L + D +ILT ++ + Sbjct: 184 ERGVIVIASGGGGVPVILE-DGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 238 NFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELD 297 + TE +Q L+ V+EL++Y +E F GSM PK+ AAI FIE + ++ I L + Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAI-IAHLEKAV 301 Query: 298 AALEGKVGTVI 308 ALEGK GT + Sbjct: 302 EALEGKTGTQV 312
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 57.7 bits (139), Expect = 3e-12 Identities = 55/228 (24%), Positives = 92/228 (40%), Gaps = 15/228 (6%) Query: 16 LLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTI 75 LLL T +T F P++S+ K + N+ N+ +L +YS TF+NS + G++ Sbjct: 15 LLLATTATDFTPVPLSSNQIIKTAKASTND-NIKDLLDWYSSGSDTFTNSEVLDNSLGSM 73 Query: 76 HATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGI---KDQETIDSFALSQETFTGGV 132 ++ + S + P + + + + VD+ K Q T + + + GV Sbjct: 74 R---IKNTDGSISLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQI--SGV 128 Query: 133 TPA-ATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYN 191 T L V K + + + +K L + LDF IR L + LY Sbjct: 129 TNTEKLPTPIELPLKV--KVHGKDSPLKYG-PKFDKKQLAISTLDFEIRHQLTQIHGLYR 185 Query: 192 NSYNKGQI-KITGADNN-YTIDLSKRLPSTDANRYVKKPQNAKIEVIL 237 +S G KIT D + Y DLSK+ + + IE + Sbjct: 186 SSDKTGGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEI 233
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 48.5 bits (115), Expect = 4e-09 Identities = 53/223 (23%), Positives = 87/223 (39%), Gaps = 12/223 (5%) Query: 1 MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHF 60 M+K + N + + LLL T P+ S A + D NI +L+ +Y+ Sbjct: 1 MNKKLLMNFFIVSPLLLATTATDFTPVPLSSNQIIKTAKASTND--NIKDLLDWYSSGSD 58 Query: 61 SFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKD-KDTDQ 119 +F+N DN + +K S + ++ + + + K VD+ + K Sbjct: 59 TFTN--SEVLDNSLGSMRIKNTDGSISLIIFPSP-YYSPAFTKGEKVDLNTKRTKKSQHT 115 Query: 120 LWWSYRETFTGGVTPAAK-PSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFR 178 +Y GVT K P+ L V+ K + K +K L + +DF Sbjct: 116 SEGTYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYGPKF---DKKQLAISTLDFE 172 Query: 179 AREALIKNKILYNENLNKGKL-KIT-GGGNNYTIDLSKRLHSD 219 R L + LY + G KIT G+ Y DLSK+ + Sbjct: 173 IRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYN 215
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 314 bits (805), Expect = e-109 Identities = 73/318 (22%), Positives = 145/318 (45%), Gaps = 24/318 (7%) Query: 9 VTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKEN--GMHKKVFY 66 +TTTL + L+ P+AN + T DIG + ++ N G+ + + + Sbjct: 7 LTTTLSVS--LLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQF 64 Query: 67 SFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKS-GLAWPSAFKVQLQLPDNEVAQIS 125 F+ DK +NK L+++ +G I+ + Y+ + N + WP + + L+ D V+ I Sbjct: 65 DFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLI- 123 Query: 126 DYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILES 185 +Y P+N I++ TL Y GN + +GG N S ++ Y Q ++ + +E Sbjct: 124 NYLPKNKIESTNVSQTLGYNIGGNFQSAPS--LGGNGSFNYS--KSISYTQQNYVSEVEQ 179 Query: 186 PTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSL 245 K V W V N+ ++ + + LF+ + S D F+ ++ L Sbjct: 180 QNSKSVLWGVKANSFATESG-------QKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPL 232 Query: 246 LSSGFSPDFATVITMDRKASKQQTNIDVIYERVRD-----DYQLHWTSTNWKGTNTKDKW 300 + SGF+P F ++ + K S + ++ Y R D H+ ++ G + + Sbjct: 233 VQSGFNPSFIATVSHE-KGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAF 291 Query: 301 IDRS-SERYKIDWEKEEM 317 ++R+ + +Y+++W+ E+ Sbjct: 292 VNRNYTVKYEVNWKTHEI 309
>PF03309#Bvg accessory factor Length = 271 Score = 30.1 bits (68), Expect = 0.011 Identities = 32/154 (20%), Positives = 51/154 (33%), Gaps = 37/154 (24%) Query: 5 ILAADVGGTTCKLGIFTPELEQ---LHKWSIHTD---TSDSTGYTLLKGIYDSFVEKVNE 58 +LA DV T +G+ + + + +W I T+ T+D + G+ Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELA-LTIDGLI--------- 51 Query: 59 NNYNFSNVLGVGIG--VPGPVDFEKGTVNGAVNLYWPE------KVNVREIFEQFVDCPV 110 + + G VP V E V + YWP + VR VD P Sbjct: 52 -GDDAERLTGASGLSTVP-SVLHE---VRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPK 106 Query: 111 YVDND--ANIAALGEKHKGAGEGADDVVAITLGT 142 V D N A K+ + + G+ Sbjct: 107 EVGADRIVNCLAAYHKYGT------AAIVVDFGS 134
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.3 bits (76), Expect = 0.002 Identities = 29/170 (17%), Positives = 54/170 (31%), Gaps = 51/170 (30%) Query: 241 MLTVYFIAGLFGN--------FVSLSFNTTTISVGASGAIFGLIGSIFAMMY---VSKTF 289 ++ V+FI L G F F+ ++G S A FG++ S+ M V+ Sbjct: 215 LMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARL 274 Query: 290 NKK----------MLGQLLIA-----------LVILVGVSLFMS------NINIVAHIGG 322 ++ G +L+A +V+L + M + + G Sbjct: 275 GERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQG 334 Query: 323 FIGGLLITL-----------IGYYYKVNRNIF--WILLIGMLVIFIALQI 359 + G L L Y + + W + G + + L Sbjct: 335 QLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPA 384
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 96.2 bits (239), Expect = 5e-25 Identities = 64/257 (24%), Positives = 107/257 (41%), Gaps = 24/257 (9%) Query: 53 DAKRIVVLEYSFADALAALDVKPVGIADDGKKKRIIK--PVREKIGDYTSVGTRKQPNLE 110 D RIV LE+ + L AL + P G+AD + + P+ + + D VG R +PNLE Sbjct: 34 DPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVID---VGLRTEPNLE 90 Query: 111 EISKLKPDLIIADSSRHKGINKELNKIAPTLSLKSFDGDYKQNI--NSFKTIAKALNKEK 168 ++++KP ++ S+ + + L +IAP DG + S +A LN + Sbjct: 91 LLTEMKPSFMVW-SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQS 149 Query: 169 EGEKRLAEHDKLINKYKDEIKFDRNQKVLPAVV---AKAGLLAHPNYSYVGQFLNELGFK 225 E LA+++ I K R + L + L+ PN S + L+E G Sbjct: 150 AAETHLAQYEDFIRSMKPRF-VKRGARPLLLTTLIDPRHMLVFGPN-SLFQEILDEYGIP 207 Query: 226 NALSDDVTKGLSKYLKGPYLQLDTEHLADLNPERMIIMTDHAKKDSAEFKKLQEDATWKK 285 NA +G + + + + LA ++ DH +S + L W+ Sbjct: 208 NAW-----QGETNFWG--STAVSIDRLAAYKDVDVLCF-DHD--NSKDMDALMATPLWQA 257 Query: 286 LNAVKNNRVDIVDRDVW 302 + V+ R V VW Sbjct: 258 MPFVRAGRFQRVP-AVW 273
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 39.4 bits (92), Expect = 1e-05 Identities = 59/325 (18%), Positives = 119/325 (36%), Gaps = 33/325 (10%) Query: 4 VNINISKIKYNAKVLQTVFQSKNMQFTPVIKCIAGDRTIVESLKALG-INHVAESRLDNI 62 ++++ +K N +++ + + + V+K A I A+G + A L+ Sbjct: 7 ASLDLQALKQNLSIVRQA--ATHARVWSVVKANAYGHGIERIWSAIGATDGFALLNLEEA 64 Query: 63 ISIADQDLTYTLLRTPAKKEISDMIEKVDMSIQTELSTIHQINEVAEV-LGKKHKILLMV 121 I++ ++ +L D+ + T + + Q+ + L I L V Sbjct: 65 ITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKV 124 Query: 122 DWKDGREGVLTYDVLDYIKEIIHLKNIHFVGLAFNFMCFKSDAPSDDDIFMINRFVSAVE 181 + R G VL +++ + N+ + L +F ++ P D + R A E Sbjct: 125 NSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAE--AEHP-DGISGAMARIEQAAE 181 Query: 182 REIGYRLKIISGGNSSMLPQLLYNDLGKINELRIGETLFRGVDTTTNQAIAML-YQDAIT 240 + R + + + P+ ++ +R G L+ + + IA + +T Sbjct: 182 -GLECRRSLSNSAATLWHPEAHFD------WVRPGIILYGASPSGQWRDIANTGLRPVMT 234 Query: 241 LEAEILEIK-----PRVN-----TQTHESFLQAIVDIGYLD---TKVDNISPM---DQHI 284 L +EI+ ++ RV T E + IV GY D +P+ Sbjct: 235 LSSEIIGVQTLKAGERVGYGGRYTARDEQRI-GIVAAGYADGYPRHAPTGTPVLVDGVRT 293 Query: 285 NILGA-SSDHLMLDLNGQGHYQVGD 308 +G S D L +DL +G Sbjct: 294 MTVGTVSMDMLAVDLTPCPQAGIGT 318
>PF04183#IucA / IucC family Length = 580 Score = 256 bits (656), Expect = 7e-80 Identities = 92/456 (20%), Positives = 176/456 (38%), Gaps = 56/456 (12%) Query: 166 EGHPTHPLTKTKLPLTMEEVRAYAPEFEKEIPLQIMMIEKDHVVCTAMDGND--QFIIDE 223 GHP K + E + YAPE+ L + ++++H++ + D Q + Sbjct: 134 SGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLTAA 193 Query: 224 IIPEYYNQIRVFLKSLGLKSEDYRAILVHPWQYDHTIGKYFEAWIAKKILIPT-PFTILS 282 + P+ + + + GL ++ + VHPWQ+ I F A A+ ++ F Sbjct: 194 MDPQEFARFSQVWQENGL-DHNWLPLPVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQW 252 Query: 283 KATLSFRTMSLIDKP--YHVKLPVDAQATSAVRTVSTVTTVDGPKLSYALQN-------- 332 A S RT++ + +KLP+ TS R + GP S LQ Sbjct: 253 LAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATL 312 Query: 333 ------MLNQYPVFKVAMEPFGEYANVDKDRARQLACIIRQKPE--IDGKGATVVSASLV 384 +L + V+ E + A L I R+ P + + V+ A+L+ Sbjct: 313 VQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLM 372 Query: 385 NKNPIDQKVIVDSYLEWLNQGITKESITTFIERYAQALIPPLIAFIQNYGIALEAHMQNT 444 + +Q + +Y++ G+ E+ ++ + + ++ PL + YG+AL AH QN Sbjct: 373 ECDENNQPLA-GAYID--RSGLDAET---WLTQLFRVVVVPLYHLLCRYGVALIAHGQNI 426 Query: 445 VVNLGPHFDIQFLVRDLGGS-RI------DLETLQHRVSDI--KITNDSLIADSIDAVIA 495 + + + L++D G R+ ++++L V D+ +++ D LI D Sbjct: 427 TLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFV 486 Query: 496 KFQHAVIQNQMAELIHHFNQYDCVEETELFNIVQQVVA--HAINPTLPHANELKDILFGP 553 I V E + ++ V++ +P + L LF P Sbjct: 487 TV---------LRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFS-LFRP 536 Query: 554 TITVKALLNMRM-----ENKVKQYLNI--ELDNPIK 582 I L +++ + + N +L NP+ Sbjct: 537 QIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLW 572
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.6 bits (95), Expect = 8e-06 Identities = 53/340 (15%), Positives = 105/340 (30%), Gaps = 26/340 (7%) Query: 6 FSSSFLLFLGNWIGQIGLNWFVLTTYHN--------AVYLGIVNFCRLVPILLLSVWAGA 57 S+ L +G IGL VL + GI+ + + GA Sbjct: 11 LSTVALDAVG-----IGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 58 IADKYDKGRLLRITISSSFLVTAILCVLTYSFTAIPISVIIIYAT-LRGILSAVETPLRQ 116 ++D++ + R + S A+ Y+ A + ++Y + ++ + Sbjct: 66 LSDRFGR----RPVLLVSLAGAAV----DYAIMATAPFLWVLYIGRIVAGITGATGAVAG 117 Query: 117 AILPDLSDKISTTQAVSFHSFIINICRSIGPAIAGVILAVYHAPTTFLAQA--ICYFIAV 174 A + D++D + F S GP + G++ F A A F+ Sbjct: 118 AYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTG 177 Query: 175 LLCLPLHFKVTKIPEDASRYMPLKVIIDYFKLHMEGRQIFITSLLIMATGFSYTTLLPVL 234 LP K + P PL + + + ++ G L + Sbjct: 178 CFLLPESHKGERRPLRREALNPLASFRWARGMTVVA-ALMAVFFIMQLVGQVPAALWVIF 236 Query: 235 TNKVFPGKSEIFGIAMTMCAIGGIIATLVL-PKVLKYIGMVNMYYLSSFLFGIALLGVVF 293 F + GI++ I +A ++ V +G L G + + F Sbjct: 237 GEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAF 296 Query: 294 HNIVIMFICITLIGLFSQWARTTNRVYFQNNVKDYERGKV 333 M I ++ + V + +G++ Sbjct: 297 ATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQL 336 Score = 30.6 bits (69), Expect = 0.012 Identities = 37/180 (20%), Positives = 71/180 (39%), Gaps = 21/180 (11%) Query: 10 FLLFLGNWIGQIGLNWFVLTTYH----NAVYLGI-VNFCRLVPILLLSVWAGAIADKYDK 64 + F+ +GQ+ +V+ +A +GI + ++ L ++ G +A + + Sbjct: 217 AVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGE 276 Query: 65 GRLLRITISSSFLVTAILCVLTYSFTAIPISVIIIYATLRGILSAVETPLRQAILPDLSD 124 R L + + + +L T + A PI V++ + P QA+L D Sbjct: 277 RRALMLGMIADGTGYILLAFATRGWMAFPIMVLLA-------SGGIGMPALQAMLSRQVD 329 Query: 125 KISTTQAVSFHSFIINICRSIGPAIAGVILAVYHAPT----TFLAQAICYFIAVLLCLPL 180 + Q + + ++ +GP + I A T ++A A Y LLCLP Sbjct: 330 EERQGQLQGSLAALTSLTSIVGPLLFTAIYA-ASITTWNGWAWIAGAALY----LLCLPA 384
>PF04183#IucA / IucC family Length = 580 Score = 268 bits (687), Expect = 1e-83 Identities = 93/475 (19%), Positives = 181/475 (38%), Gaps = 45/475 (9%) Query: 197 SEQAVIEGHPLHPGAKLRKGLNALQTFLYSSEFNQPIKLKIVLIHSKLSRTMSLSKDYDT 256 Q ++ GHP K R+G Y+ E+ +L + + + M D + Sbjct: 128 RLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKRE---HMIWRCDNEM 184 Query: 257 TVHQLF-----PDLIKQLENEFTPKFNFNDYHIMIVHPWQLDDVLHSDYQAEVDKELIIE 311 +HQL P + + +++ + VHPWQ + +D+ A+ + ++ Sbjct: 185 DIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEGRMVS 244 Query: 312 AKHTLD-YYAGLSFRTLVPKYPAMSPHIKLSTNVHITGEIRTLSEQTTHNGPLMTRILND 370 D + A S RTL IKL ++ T R + + GPL +R L Sbjct: 245 LGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQ 304 Query: 371 ILEKDVIFKSYASTIIDEVAGIHFYNEQDEADYQTER--SEQLGTLFRKNIYQMIPQEVT 428 + D + I+ E A + +E A + E LG ++R+N + + + + Sbjct: 305 VFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDES 364 Query: 429 PLIPSSLVATYPFNNESPIVTLIKRYQSAASLSDFESSAKSWVETYSKALLGLVIPLVTK 488 P++ ++L+ N P+ A + A++W+ + ++ + L+ + Sbjct: 365 PVLMATLMECDE--NNQPLA--------GAYIDRSGLDAETWLTQLFRVVVVPLYHLLCR 414 Query: 489 YGIALEAHLQNAIATFRKDGLLDTMYIRDFEG-LRIDKAQLNEMGYSTSHFHEKSRILTD 547 YG+AL AH QN I K+G+ + ++DF+G +R+ K + EM S E + + Sbjct: 415 YGVALIAHGQN-ITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMD---SLPQEVRDVTSR 470 Query: 548 SKTSVFNKAFYSTVQNHLGELILTISKASNDSNLERHMWYIVRDVLDNIFDQLVLSTHKS 607 + + I + ER + ++ VL + + H Sbjct: 471 LSADYLIHDLQTGHFVTVLRFISPLMVRLGVP--ERRFYQLLAAVLSDYMKK-----HPQ 523 Query: 608 NQVNENRINEIKDTMFAPFIDYKCVTTMRLE----DEAHHY--TYIK-VNNPLYR 655 + +F P I + ++L D Y++ + NPL+ Sbjct: 524 MSERFALFS-----LFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLWL 573
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 28.7 bits (64), Expect = 0.012 Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 5/43 (11%) Query: 99 VDLKVILEYGE-----SAPKIFRKVTELVKEQVKYITGLDVVE 136 D K+ +YG S P FR + +V EQV G +++E Sbjct: 495 TDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLE 537
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 159 bits (403), Expect = 1e-44 Identities = 92/415 (22%), Positives = 187/415 (45%), Gaps = 16/415 (3%) Query: 140 KILAALLFGMFIAILNQTLLNVALPKINTEFNISASTGQWLMTGFMLVNGILIPITAYLF 199 +IL L F ++LN+ +LNV+LP I +FN ++ W+ T FML I + L Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 200 NKYSYRKLFLVALVLFTIGSLICAISMN-FPIMMVGRVLQAIGAGVLMPLGSIVIITIYP 258 ++ ++L L +++ GS+I + + F ++++ R +Q GA L +V+ P Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 259 PEKRGAAMGTMGIAMILAPAIGPTLSGYIVQNYHWNVMFYGMFIIGIIAILIGFVWFKLY 318 E RG A G +G + + +GP + G I HW+ + +I II + K Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIP-MITIITVPFLMKLLKKE 192 Query: 319 QYTTNPKADIPGIIFSTIGFGALLYGFSEAGNKGWGSVEIETMFAIGIIFIILFVIRELR 378 DI GII ++G + + + ++ ++FV + Sbjct: 193 VRIKGH-FDIKGIILMSVGIVFFMLF---TTSYSIS------FLIVSVLSFLIFVKHIRK 242 Query: 379 MKSPMLNLEVLKFPTFTLTTIINMVVMLSLYGGMILLPIYLQNLRGFSALDSG-LLLLPG 437 + P ++ + K F + + ++ ++ G + ++P ++++ S + G +++ PG Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 438 SLIMGLLGPFAGKLLDTIGLKPLAIFGIAVMTYATWELTKLNMDTP-YMTIMGIYVLRSF 496 ++ + + G G L+D G + G+ ++ + + L T +MTI+ ++VL Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVL--G 360 Query: 497 GMAFIMMPMVTAAINALPGRLASHGNAFLNTMRQLAGSIGTAILVTVMTTQTTQH 551 G++F + T ++L + A G + LN L+ G AI+ +++ Sbjct: 361 GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQ 415
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 59.1 bits (143), Expect = 2e-12 Identities = 26/133 (19%), Positives = 45/133 (33%), Gaps = 13/133 (9%) Query: 87 MDLKMPQKGTIAKLD-GMEGSMVQAGNPIAYAYNLDD-LYVTANIDEKDIKDVEVGKDVD 144 ++ P + +L EG +V + DD L VTA + KDI + VG++ Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAI 387 Query: 145 VTIDGQKAS----IKGKVDSIGKATAASFSLMPSSNSDGNYTKVSQVIPVKITLESEPSK 200 + ++ + + GKV +I G V I + Sbjct: 388 IKVEAFPYTRYGYLVGKVKNINLDAI-------EDQRLGLVFNVIISIEENCLSTGNKNI 440 Query: 201 QVVPGMNAEVKIH 213 + GM +I Sbjct: 441 PLSSGMAVTAEIK 453 Score = 31.7 bits (72), Expect = 0.002 Identities = 17/77 (22%), Positives = 35/77 (45%), Gaps = 2/77 (2%) Query: 9 VITVVVLLAIGIAGFYFWNKTTSYVTTDNAKV--NGDQIKIASPASGQIKSLNVKQGDKL 66 ++ ++ + IA V T N K+ +G +I + +K + VK+G+ + Sbjct: 59 LVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESV 118 Query: 67 DKGDKVAIVTVQGQDGE 83 KGD + +T G + + Sbjct: 119 RKGDVLLKLTALGAEAD 135
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.0 bits (106), Expect = 3e-08 Identities = 13/69 (18%), Positives = 24/69 (34%) Query: 2 KRQAKIEIQNALVDLMAEYPFQEISTKMICAYCNINRSTFYDYYKDKFDLLDTINSKHKE 61 ++ + I + + L ++ S I + R Y ++KDK DL I + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 62 KFQFLLSAL 70 L Sbjct: 69 NIGELELEY 77
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 66.4 bits (162), Expect = 4e-14 Identities = 69/386 (17%), Positives = 142/386 (36%), Gaps = 16/386 (4%) Query: 15 IIILGSLTAIGALSIDMFLPGLPDIRHDF---QTTTSNAQLTLSMFMIGLAFGNLFAGPI 71 +I++ S A+ A+ I + +P LP + D T++ + L+++ + G + Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 72 SDSTGRRKPLIIAMIIFTLASLGIVFVHNIWLMVALRFLQGVTGGAAAVISRAIASDMYS 131 SD GRR L++++ + + +W++ R + G+TG AV IA D+ Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA-DITD 125 Query: 132 GNELTKFMALLMLVNGIAPVVAPTIGGIILNYSVWRMVFVILTIFGFVMVIGSLLKVPES 191 G+E + + G V P +GG++ +S F + + +PES Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP-HAPFFAAAALNGLNFLTGCFLLPES 184 Query: 192 LTVTNRESSSGLKTMFKNFKILLKTLRFVLPMLIQGMTFVILFTYISASPFII--QKIYG 249 R +F+ + + V ++ + L + A+ ++I + + Sbjct: 185 HKGERRPLRREALNPLASFR-WARGMTVVAALMAVFFI-MQLVGQVPAALWVIFGEDRFH 242 Query: 250 MTAIQFSWMFAGIGITLIISSQLTGYLVDFIDSQKLMRGMTMIQIIGVILVTIVLLNHWN 309 A A GI ++ + + ++ R M+ +I I+L Sbjct: 243 WDATTIGISLAAFGILHSLAQ---AMITGPVAARLGERRALMLGMIADGTGYILLAFATR 299 Query: 310 FWILAIGFIILIAPVTGVATLGFTIAMDESSSGRGSSSSLLGLVQFLFGGVASPLVGVKG 369 W+ ++L + G+ L ++ +G L + L + PL+ Sbjct: 300 GWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSL-TSIVGPLLFTAI 358 Query: 370 EDNPIPY---IIIIIATAVILIILQI 392 I I A+ L+ L Sbjct: 359 YAASITTWNGWAWIAGAALYLLCLPA 384
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.014 Identities = 11/21 (52%), Positives = 14/21 (66%) Query: 35 VILNGASGSGKTTLLTILGGL 55 V+L G G GK+TL+ L GL Sbjct: 599 VVLEGTGGIGKSTLINTLVGL 619
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 51.5 bits (123), Expect = 9e-11 Identities = 24/112 (21%), Positives = 45/112 (40%), Gaps = 7/112 (6%) Query: 40 FFKDNYTVEKFTQEINHVDSFHYFYQEDGANVGYIKMNINSAQTEEMGETYLEVQRIYFL 99 +FK + + + Y + +G IK+ N Y ++ I Sbjct: 46 YFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNG-------YALIEDIAVA 98 Query: 100 KDFQGGGRGSQLIELAEKIAQEHNKHKIWLGVWEHNPRAQAFYKRHGFKVVG 151 KD++ G G+ L+ A + A+E++ + L + N A FY +H F + Sbjct: 99 KDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150
>PF03627#PapG Length = 336 Score = 29.1 bits (65), Expect = 0.023 Identities = 15/48 (31%), Positives = 19/48 (39%), Gaps = 5/48 (10%) Query: 21 TFKQLSPTDLPKGDVLIKVHY-SGINYKDALATQDH----NAVVKSYP 63 FK P DLP GD + + Y SG+ A V K+ P Sbjct: 155 IFKVALPADLPLGDYSVTIPYTSGMQRHFASYLGARFKIPYNVAKTLP 202
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 35.3 bits (81), Expect = 3e-05 Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 9/60 (15%) Query: 66 IVDIAVLKSYQGQGYGSLIMEHIMQYIK-----GVAVESTYVSLIADYPADKLYTKFGFI 120 I DIAV K Y+ +G G+ ++ +++ K G+ +E+ +++ A Y K FI Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINI----SACHFYAKHHFI 147
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.5 bits (128), Expect = 5e-11 Identities = 34/203 (16%), Positives = 77/203 (37%), Gaps = 21/203 (10%) Query: 5 RRIRKTKSSIKQAFTKLLQEKDLEKITIRDITTRADINRGTFYLHYEDKYMLLADMEDEY 64 + ++T+ I +L ++ + ++ +I A + RG Y H++DK L +++ + Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 65 ISELTTY----------TQFDLLRGSSIEDIANTFVNNILKNIFQHIHDNLEFY---HTI 111 S + +LR I + +T + + + I EF + Sbjct: 67 ESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVV 126 Query: 112 LQLERTSQLEL--KINEHIKNNMQR-YISINHSIGGVPEMYFYSYVSGATISIIKYWVMD 168 Q +R LE +I + +K+ ++ + + + Y+SG + W+ Sbjct: 127 QQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAII-MRGYISGLMEN----WLFA 181 Query: 169 KQPISVDELAKHVHNIIFNGPLR 191 Q + + A+ I+ L Sbjct: 182 PQSFDLKKEARDYVAILLEMYLL 204
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 428 bits (1103), Expect = e-154 Identities = 213/312 (68%), Positives = 247/312 (79%), Gaps = 8/312 (2%) Query: 1 MIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGA--EIIKRTQDITSKRLAITQ 58 M+KNKILT TL+V L+APLANP +E +KA N EDIG+G+ EIIKRT+D TS + +TQ Sbjct: 1 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 Query: 59 NIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNV 118 NIQFDFVKDKKYNKDAL++KMQGFISSRTTY + KK ++K M WPFQYNI LKT D V Sbjct: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYV 120 Query: 119 DLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQKNYVTEVESQ 178 LINYLPKNKI+S +VSQ LGYNIGGNFQSAPS+GG+GSFNYSK+ISY Q+NYV+EVE Q Sbjct: 121 SLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQ 180 Query: 179 NSKGVKWGVKANSFVTPNGQVSAYDQYLF-AQDPTGPAARDYFVPDNQLPPLIQSGFNPS 237 NSK V WGVKANSF T +GQ SA+D LF P RDYFVPD++LPPL+QSGFNPS Sbjct: 181 NSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPS 240 Query: 238 FITTLSHERGKGDKSEFEITYGRNMDATYA-----YVTRHRLAVDRKHDAFKNRNVTVKY 292 FI T+SHE+G D SEFEITYGRNMD T+A + L R H+AF NRN TVKY Sbjct: 241 FIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKY 300 Query: 293 EVNWKTHEVKIK 304 EVNWKTHE+K+K Sbjct: 301 EVNWKTHEIKVK 312
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 468 bits (1205), Expect = e-170 Identities = 315/315 (100%), Positives = 315/315 (100%) Query: 1 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ Sbjct: 1 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 Query: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYV 120 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYV Sbjct: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYV 120 Query: 121 SLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQ 180 SLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQ Sbjct: 121 SLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQ 180 Query: 181 NSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPS 240 NSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPS Sbjct: 181 NSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPS 240 Query: 241 FIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKY 300 FIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKY Sbjct: 241 FIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKY 300 Query: 301 EVNWKTHEIKVKGQN 315 EVNWKTHEIKVKGQN Sbjct: 301 EVNWKTHEIKVKGQN 315
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 383 bits (985), Expect = e-136 Identities = 87/322 (27%), Positives = 160/322 (49%), Gaps = 18/322 (5%) Query: 1 MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQ 60 M NK++ ++++ S+ L + + + K T S+K+ ++Q Sbjct: 1 MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQ 60 Query: 61 ILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSK-LYWGAKYNVSISSQSNDS 119 + F+F+KDK Y+KD L+LK G I+S N + K + W +YN+ + + ++ Sbjct: 61 NIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKT-NDKY 119 Query: 120 VNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTL 179 V++++Y PKN+ E V TLGY GG+ + L G NG+ +S++I+Y Q++Y + + Sbjct: 120 VSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGG--NGSFNYSKSISYTQQNYVSEV 177 Query: 180 SRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQM 239 + N K+V WGV+A+ + ++LF+ + S F+ ++ Sbjct: 178 EQQ-NSKSVLWGVKANSFATESGQ-------KSAFDSDLFVGYKPHSKDPRDYFVPDSEL 229 Query: 240 PLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDL-----YQIRWNGFYWAGANYKN 294 P L +S FNP F++ +SH + + S+ +TY R MD+ + Y G N Sbjct: 230 PPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHN 289 Query: 295 -FKTRTFKSTYEIDWENHKVKL 315 F R + YE++W+ H++K+ Sbjct: 290 AFVNRNYTVKYEVNWKTHEIKV 311
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 28.5 bits (63), Expect = 0.048 Identities = 8/47 (17%), Positives = 15/47 (31%), Gaps = 3/47 (6%) Query: 233 GGVILSSND---VKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLIN 276 IL+ N+ L I + + FI+ ++E Sbjct: 59 SSQILNPNETGTFSQSLTKSKEVSINVNFSVGFTSEFIQASVEYGFG 105
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 43.1 bits (101), Expect = 1e-07 Identities = 15/58 (25%), Positives = 28/58 (48%) Query: 5 KSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIATLNRATFYAHFTDKEDLLD 62 + T+Q ++D L++ ++ +S ++ +I A + R Y HF DK DL Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 27.4 bits (60), Expect = 0.019 Identities = 14/45 (31%), Positives = 23/45 (51%) Query: 56 FQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGTVVQE 100 F+N Q +N + N I G ++ V+Q+ + KEAG Q+ Sbjct: 291 FKNPENQKVNIDANGNAIPSGELKDDIVEQIAQQAKEAGEVARQQ 335
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 35.1 bits (81), Expect = 2e-04 Identities = 31/131 (23%), Positives = 46/131 (35%), Gaps = 21/131 (16%) Query: 1 MKDILVIGATGKQGNAVVKQLLEDGWYVSAL--------TRNKNNRKLSDIGHPHLSIVE 52 MK LV GA G G V K+LLE G V + K R L + P + Sbjct: 1 MK-YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQAR-LELLAQPGFQFHK 58 Query: 53 GDLSDSVSLQSAMKGKYGLYSIQPIVKDDVSEELRQG-----------MKIIEIAEQENI 101 DL+D + + + V L + I+E I Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 102 QHIVYSTAGGV 112 QH++Y+++ V Sbjct: 119 QHLLYASSSSV 129
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.0 bits (150), Expect = 2e-14 Identities = 25/80 (31%), Positives = 44/80 (55%) Query: 1 MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQ 60 +++A+E RQ I ++A +LF ++GV + S+ IAK G+ G +Y HFKDKSDL + + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 RDLDIFITHFKQIKDDYHSN 80 + + + + Sbjct: 65 LSESNIGELELEYQAKFPGD 84
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 68.9 bits (168), Expect = 3e-16 Identities = 48/197 (24%), Positives = 76/197 (38%), Gaps = 18/197 (9%) Query: 3 KIVLITGGNKGLGYASAEALKALGYKVYIGSRND---VRGQQASQKLGVHYVQ--LDVTS 57 KI ITG +G+G A A L + G + N + + + H DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 58 DYSVKNAYNMIAEKEGRLDILINNAGISGQFSTPSKLTPRDVEEVYQTNVFGIVRMMNTF 117 ++ I + G +DIL+N AG+ + L+ + E + N G+ + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 118 VPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSKSAVTMLTLQYAKGLP- 176 + +V V S P T+ + AY SSK+A M T L Sbjct: 128 SKYMMDRRSGSIVTVGSNPAG-----VPRTSMA-----AYASSKAAAVMFTKCLGLELAE 177 Query: 177 -NMQINAADPGATNTDL 192 N++ N PG+T TD+ Sbjct: 178 YNIRCNIVSPGSTETDM 194
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 50.8 bits (121), Expect = 8e-09 Identities = 24/94 (25%), Positives = 35/94 (37%), Gaps = 16/94 (17%) Query: 543 PVDPTPGPPVDPEPEPEPTPDPE-----PSPEPEPEPTPDPEPSPEPDP----------- 586 P P P EPEPEP P PE P +P+P P P+P P Sbjct: 58 PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPV 117 Query: 587 DSDSDSDSGSDSDSGSDSDSDSDSDSDSDSDSNS 620 +S S + + + S + + + S + S Sbjct: 118 ESRPASPFENTAPARLTSSTATAATSKPVTSVAS 151 Score = 48.8 bits (116), Expect = 3e-08 Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 1/47 (2%) Query: 541 VNPVDPTPGPPVDPEPEPEPTPDPEPSPEPEPEP-TPDPEPSPEPDP 586 V P D P V P PEP P+PEP P PEP P P+P P Sbjct: 50 VTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP 96 Score = 47.3 bits (112), Expect = 1e-07 Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 8/84 (9%) Query: 541 VNPVDPTPGPPVDPEPE-------PEPTPDPEPSPEPEPEPTPDPEPSP-EPDPDSDSDS 592 V +P P P +P E P+P P P+P P + + P + P E P S ++ Sbjct: 68 VVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFEN 127 Query: 593 DSGSDSDSGSDSDSDSDSDSDSDS 616 + + S + + + S + S Sbjct: 128 TAPARLTSSTATAATSKPVTSVAS 151 Score = 40.0 bits (93), Expect = 2e-05 Identities = 20/45 (44%), Positives = 20/45 (44%), Gaps = 3/45 (6%) Query: 543 PVDPTPGPPVDPEPEPEP---TPDPEPSPEPEPEPTPDPEPSPEP 584 P P V P P P PEP EPEPEP P PEP E Sbjct: 41 PAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEA 85 Score = 30.3 bits (68), Expect = 0.028 Identities = 9/28 (32%), Positives = 10/28 (35%), Gaps = 1/28 (3%) Query: 560 PTPDPEPSPEPEPEPTPDPEPSPEPDPD 587 P P P EP PEP+P Sbjct: 52 PADLEPPQAVQPPPEPV-VEPEPEPEPI 78
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 388 bits (998), Expect = e-138 Identities = 137/314 (43%), Positives = 198/314 (63%), Gaps = 5/314 (1%) Query: 1 MKEKIVIALGGNAIQT--KEATAEAQQTAIRRAMQNLKPLFDSPARIVISHGNGPQIGGL 58 M +++VIALGGNA+Q ++ + E +R+ + + + +VI+HGNGPQ+G L Sbjct: 1 MGKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSL 60 Query: 59 LIQQAKSNSDT-TPAMPLDTCGAMSQGMIGYWLETEINRILTEMNSDRTVGTIVTRVEVD 117 L+ + PA P+D GAMSQG IGY ++ + L + ++ V TI+T+ VD Sbjct: 61 LLHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVD 120 Query: 118 KDDPRFDNPTKPIGPFYTKEEVEELQKEQPGSVFKEDAGRGYRKVVASPLPQSILEHQLI 177 K+DP F NPTKP+GPFY +E + L +E G + KED+GRG+R+VV SP P+ +E + I Sbjct: 121 KNDPAFQNPTKPVGPFYDEETAKRLARE-KGWIVKEDSGRGWRRVVPSPDPKGHVEAETI 179 Query: 178 RTLADGKNIVIACGGGGIPVIKKENTYEGVEAVIDKDFASEKLATLIEADTLMILTNVEN 237 + L + IVIA GGGG+PVI ++ +GVEAVIDKD A EKLA + AD MILT+V Sbjct: 180 KKLVERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNG 239 Query: 238 VFINFNEPNQQQIDDIDVATLKKYAAQGKFAEGSMLPKIEAAIRFVESGENKKVIITNLE 297 + + +Q + ++ V L+KY +G F GSM PK+ AAIRF+E G ++ II +LE Sbjct: 240 AALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWG-GERAIIAHLE 298 Query: 298 QAYEALIGNKGTHI 311 +A EAL G GT + Sbjct: 299 KAVEALEGKTGTQV 312
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 508 bits (1309), Expect = 0.0 Identities = 193/409 (47%), Positives = 275/409 (67%), Gaps = 8/409 (1%) Query: 5 PIKVNSEIGALKTVLLKRPGKELENLVPDYLDGLLFDDIPYLEVAQKEHDHFAQVLREEG 64 PI + SEIG LK VLL RPG+ELENL P + LFDDIPYLEVA++EH+ FA +L+ Sbjct: 7 PINIFSEIGRLKKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQEHEVFASILKNNL 66 Query: 65 VEVLYLEKLAAESIENPQ-VRSEFIDDVLAESKKTILGHEEEIKALFATLSNQELVDKIM 123 VE+ Y+E L +E + + + ++FI + E++ +K F++L+ ++ K++ Sbjct: 67 VEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINLLKDYFSSLTIDNMISKMI 126 Query: 124 SGVRKEEINPKCTHLVEYMDDKYPFYLDPMPNLYFTRDPQASIGHGITINRMFWRARRRE 183 SGV EE+ + L + ++ F +DPMPN+ FTRDP ASIG+G+TIN+MF + R+RE Sbjct: 127 SGVVTEELKNYTSSLDDLVNGANLFIIDPMPNVLFTRDPFASIGNGVTINKMFTKVRQRE 186 Query: 184 SIFIQYIVKHHPRFKDANIPIWLDRDCPFNIEGGDELVLSKEVLAIGVSERTSAQAIEKL 243 +IF +YI K+HP +K N+PIWL+R ++EGGDELVL+K +L IG+SERT A+++EKL Sbjct: 187 TIFAEYIFKYHPVYK-ENVPIWLNRWEEASLEGGDELVLNKGLLVIGISERTEAKSVEKL 245 Query: 244 ARRIFENPQATFKKVVAIEIPTSRTFMHLDTVFTMIDYDKFTIHSAILKAEGNMNIFIIE 303 A +F+N + +F ++A +IP +R++MHLDTVFT IDY FT ++ + +I+++ Sbjct: 246 AISLFKN-KTSFDTILAFQIPKNRSYMHLDTVFTQIDYSVFTSFTSD---DMYFSIYVLT 301 Query: 304 YDDVNKDISIK-QSSHLKDTLEDVLGIDDIQFIPTGNGDVIDGAREQWNDGSNTLCIRPG 362 Y+ + I IK + + +KD L LG I I GD+I GAREQWNDG+N L I PG Sbjct: 302 YNPSSSKIHIKKEKARIKDVLSFYLG-RKIDIIKCAGGDLIHGAREQWNDGANVLAIAPG 360 Query: 363 VVVTYDRNYVSNDLLRQKGIKVIEISGSELVRGRGGPRCMSQPLFREDI 411 ++ Y RN+V+N L + GIKV I SEL RGRGGPRCMS PL REDI Sbjct: 361 EIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGPRCMSMPLIREDI 409
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 82.2 bits (203), Expect = 6e-23 Identities = 39/147 (26%), Positives = 78/147 (53%), Gaps = 2/147 (1%) Query: 1 MKKSKRLEIVSTIVKKHKIYKKEQIISYIEEYFGVRYSATTIAKDLKELNIYRVPIDCET 60 M K +R + I+ ++I +++++ +++ G + T+++D+KEL++ +VP + + Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKD-GYNVTQATVSRDIKELHLVKVPTNNGS 59 Query: 61 WIYKAINNQTEQEMREKFKHYCEHEVLSSIINGAYIIVKTSPGFAQGINYFIDQLNIEEI 120 + Y ++ K K + I++KT PG AQ I +D L+ EEI Sbjct: 60 YKY-SLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEEI 118 Query: 121 LGTVSGNDTTLILTASNDMAEYVYAKL 147 +GT+ G+DT LI+ ++D + V K+ Sbjct: 119 MGTICGDDTILIICRTHDDTKVVQKKI 145
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 437 bits (1126), Expect = e-151 Identities = 176/477 (36%), Positives = 249/477 (52%), Gaps = 42/477 (8%) Query: 67 QDYSVTDVKTDKKGFTHYTLQPSVDGVHAPDKEVKVHADKSGKVVLING----DTDAKKV 122 + S+ K D+ G T + ++ + H + G++ ++G + D + + Sbjct: 74 ERLSLIGNKLDELGHTVMRFEQAIAASLCMGAVLVAHVN-DGELSSLSGTLIPNLDKRTL 132 Query: 123 KPTNKVTLSKDEAADKAFNAVKIDKNKAKNLQDDVIKENKVEIDGDSNKYIYNIELITVT 182 K +++ + E K A ++ K + ++ + D ++ + Y + + +T Sbjct: 133 KTEAAISIQQAEMIAKQDVADRVTKERPAA-EEGKPTRLVIYPDEETPRLAYEVNVRFLT 191 Query: 183 PEISHWKVKIDADTGAVVEKTNLVKEA-----------AATGTGKGVLGDTKDINI--NS 229 P +W IDA G V+ K N + EA + G G+GVLGD K IN +S Sbjct: 192 PVPGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAGTSTVGVGRGVLGDQKYINTTYSS 251 Query: 230 INGGFSLEDLTHQGKLSAYNFNDQTG-QATLITNEDENFVKDDQRAGVDANYYAKQTYDY 288 G + L+D T + Y+ ++T +L + D F A VDA+YYA YDY Sbjct: 252 YYGYYYLQDNTRGSGIFTYDGRNRTVLPGSLWADGDNQFFASYDAAAVDAHYYAGVVYDY 311 Query: 289 YKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGAND 348 YKN GR SYD + I S H YG NNA W G +M+YGDGDG+TF SG D Sbjct: 312 YKNVHGRLSYDGSNAAIRSTVH---YG--RGYNNAFWNGSQMVYGDGDGQTFLPFSGGID 366 Query: 349 VVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVD-----DEDFLMGEDVYTPGKE 403 VV HELTH VT TA L Y+++SGA+NE+ SD+FG V+ + D+ +GED+YTPG Sbjct: 367 VVGHELTHAVTDYTAGLVYQNESGAINEAMSDIFGTLVEFYANRNPDWEIGEDIYTPGVA 426 Query: 404 GDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQ----------AI 453 GDALRSMS+P ++G P H +DNGGVHTNSGI NKAAY + Q I Sbjct: 427 GDALRSMSDPAKYGDPDHYSKRYTGTQDNGGVHTNSGIINKAAYLLSQGGVHYGVSVTGI 486 Query: 454 GKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAE--QVYEAWNEVGV 508 G+ K +I+YRAL YLT SNF + A QAA DLY + E V +A+N VGV Sbjct: 487 GRDKMGKIFYRALVYYLTPTSNFSQLRAACVQAAADLYGSTSQEVNSVKQAFNAVGV 543
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 38.8 bits (90), Expect = 7e-05 Identities = 25/115 (21%), Positives = 43/115 (37%), Gaps = 15/115 (13%) Query: 866 VLFVLITI-FCSIIFNSIVYTCVSLLGNPGKAIAIVLLVLQIAG----GGGTFPIQTTPQ 920 +L+ L I + F S+ +L P I L I G FP+ P Sbjct: 147 LLYALPVIALTGLAFASLGMVVTAL--APSYDYFIFYQTLVITPILFLSGAVFPVDQLPI 204 Query: 921 FFQNISPYLPFTYAIDSLRETV-----GGIVPEILITKLIILTLFGIGFFVVGLI 970 FQ + +LP +++ID +R + + + + I+ F F L+ Sbjct: 205 VFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPF---FLSTALL 256
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 64.0 bits (155), Expect = 3e-13 Identities = 50/176 (28%), Positives = 84/176 (47%), Gaps = 19/176 (10%) Query: 304 SNNDDSGQFNVVDSKDTRQFVKSIAKDAHRIGQDNDIYASVMIAQAILESDSGRSALAKS 363 N DDS D++ F+ ++ A Q + + +++AQA LES G+ + + Sbjct: 139 RNYDDSLPG------DSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRE 192 Query: 364 ---PNHNLFGIK--GAFEGNSVPFNTLEADGNQLYSINAGFRKYPSTKESLKDYSDLIKN 418 P++NLFG+K G ++G T E + + + A FR Y S E+L DY L+ Sbjct: 193 NGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTR 252 Query: 419 GIDGNRTIYKPTWKSEADSYKDATSHLSKTYATDPNYAKKLNSIIKHYQLTQFDDE 474 + + A + +DA YATDP+YA+KL ++I+ Q+ D+ Sbjct: 253 NPRYAAVTTAASAEQGAQALQDA------GYATDPHYARKLTNMIQ--QMKSISDK 300
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 77.0 bits (189), Expect = 3e-19 Identities = 41/183 (22%), Positives = 77/183 (42%), Gaps = 10/183 (5%) Query: 3 RKTALLVLDMQE----GIASSVPRIKNIIKANQRAIEAARQHRIPVIFIRLVLDKHFNDV 58 + LL+ DMQ + + + ++ Q IPV++ ++ +D Sbjct: 29 NRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDR 88 Query: 59 SSSNKVFSTIKAQGYAITEADASTRILEDLAPLEDEPIISKRRFSAFTGSYLEVYLRAND 118 + + G + +I+ +LAP +D+ +++K R+SAF + L +R Sbjct: 89 ALLTDFW------GPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEG 142 Query: 119 INHLVLTGVSTSGAVLSTALESVDKDYYITVLEDAVGDRSDDKHDFIIEQILSRSCDIES 178 + L++TG+ L TA E+ +D + DAV D S +KH +E R Sbjct: 143 RDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMALEYAAGRCAFTVM 202 Query: 179 VES 181 +S Sbjct: 203 TDS 205
>SECA#SecA protein signature. Length = 901 Score = 654 bits (1689), Expect = 0.0 Identities = 286/835 (34%), Positives = 449/835 (53%), Gaps = 68/835 (8%) Query: 10 NELRLKSIRKIVKRINTWSDEVKSYSDDVLKQKTLEFKERIASGVDTLDTLLPEAYAVAR 69 N+ L+ +RK+V IN E++ SD+ LK KT EF+ R+ G + L+ L+PEA+AV R Sbjct: 14 NDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKG-EVLENLIPEAFAVVR 72 Query: 70 EASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTN 129 EAS RV GM +VQL+G +VL+E IAEM+TGEGKTLTAT+P YLNAL+GKG +++T N Sbjct: 73 EASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVN 132 Query: 130 DYLAKRDFEEMQPLYEWLGLTASLGFVDIVDYEYQKGEKRNIYEHDIIYTTNGRLGFDYL 189 DYLA+RD E +PL+E+LGLT V I KR Y DI Y TN GFDYL Sbjct: 133 DYLAQRDAENNRPLFEFLGLT-----VGINLPGMPAPAKREAYAADITYGTNNEYGFDYL 187 Query: 190 IDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLI 249 DN+A S E + +L+Y ++DEVDSI++D A+TPL+ISG S ++ V + + LI Sbjct: 188 RDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLI 247 Query: 250 E-----------DVHFKMKKTKKEIWLLNQGIEAAQSYFNV-------EDLYSEQAMVLV 291 + HF + + +++ L +G+ + E LYS ++L+ Sbjct: 248 RQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLM 307 Query: 292 RNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQAGLHQAIEAKEGMEVST 351 ++ ALRA LF +VDY V +G+++++D TGR + G + GLHQA+EAKEG+++ Sbjct: 308 HHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQN 367 Query: 352 DKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQVPTDKAIQRIDEPDKV 411 + +A+ITFQN F+L+E +GMT T EF +Y V VPT++ + R D PD V Sbjct: 368 ENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLV 427 Query: 412 FRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVFFQMDIPNNLLIAQNVAKE 471 + + EK A+I DI E G+PVL+ T + E +E S + I +N+L A+ A E Sbjct: 428 YMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANE 487 Query: 472 AQMIAEAGQIGSMTVATSMAGRGTDIKLG-----------------------------EG 502 A ++A+AG ++T+AT+MAGRGTDI LG + Sbjct: 488 AAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDA 547 Query: 503 VEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENN 562 V GGL +I E E+ R+D QLRGRSGRQGD GSS Y+S++D L++ ++ ++ Sbjct: 548 VLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMM 607 Query: 563 QLYSLDAQRLSQSSLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEER 622 + + + + + AQR E + R+ E++ + QR +Y +R Sbjct: 608 RKLGMKPGEAIEHPWVTKAIA----NAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQR 663 Query: 623 NRVLEIDDAENRDFKVLAKDVFEMFVNEE---KVLTKSRVVEYIYQNLSFQFNKDVACVN 679 N +L++ D + +DVF+ ++ + L + + + + L F+ D+ Sbjct: 664 NELLDVSDVSET-INSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 680 FKDKQAVVT------FLLEQFEKQIALNRKNMQSAYYYNIFVQKVFLKAIDSCWLEQVDY 733 + DK+ + +L Q + ++ + A F + V L+ +DS W E + Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQ-RKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAA 781 Query: 734 LQQLKANVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKE 788 + L+ ++ R Q++ EY R + F M ++K ++ + + + +E Sbjct: 782 MDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEE 836
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 27.4 bits (61), Expect = 0.041 Identities = 9/32 (28%), Positives = 14/32 (43%) Query: 23 IPRPIAFVTTLNQDASVNAAPFSFFNIVNNHP 54 IP T + + AP+ +NI N+ P Sbjct: 234 IPHADTQWTVETGTPAASIAPYRVYNIGNSSP 265
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.2 bits (104), Expect = 4e-08 Identities = 23/101 (22%), Positives = 44/101 (43%), Gaps = 5/101 (4%) Query: 48 EKNDEVIGYIN--GPVLKERYISDDLFKNVPANNSEGGYISVLGLVVAPNYQGQGIAGRL 105 E +D + Y+ G Y+ ++ + ++ GY + + VA +Y+ +G+ L Sbjct: 51 EDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTAL 110 Query: 106 LNYFENLAKNQHRHGVTLTCRE---SLISFYEKYGYRNEGV 143 L+ AK H G+ L ++ S FY K+ + V Sbjct: 111 LHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAV 151