>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 118 bits (298), Expect = 4e-31 Identities = 76/400 (19%), Positives = 159/400 (39%), Gaps = 20/400 (5%) Query: 30 FLAAVDQTLLATATPAIVEDLGGLR-QASWITIGYMLAMAASVPIYGWLGDNYGRAKILM 88 F + +++ +L + P I D +W+ +ML + +YG L D G ++L+ Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 89 IALVVFALGSIVSA-SAGTMDHMIAGRILQGLGGGGLMSLSQSLVGELVPIRQRARFQGY 147 +++ GS++ +I R +QG G +L +V +P R + G Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 148 FAAMFTLASVGGPVIGGFVVHAYSWHWLFWANIPLV-MLAVWRLNRLHKQSVKPVRQGRF 206 ++ + GP IGG + H W +L IP++ ++ V L +L K+ V+ +G F Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLMKLLKKEVR--IKGHF 199 Query: 207 DLLGVLLFPTIITALLYWLSVAGQDFAWLSATSLGFMGFICVGALVLLWWERRRESPFLP 266 D+ G++L I + + + F +S S + + R+ PF+ Sbjct: 200 DIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL----------IFVKHIRKVTDPFVD 249 Query: 267 LDLLANKAIYMPLFTAALFAACLFAMIFFLPIYLQVGLHTNPAKTGLLLM-PMTFGIVTG 325 L N + + + + + +P ++ + A+ G +++ P T ++ Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 326 STIAGRLLSRDVAPKWLPTFGMGLAFIGLLLIGLVPPNANLIGALGV-LVGIGLGTVMPS 384 I G L+ R P ++ G+ + L + + + + V GL Sbjct: 310 GYIGGILVDR-RGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTV 368 Query: 385 VQLVVQSVSGKARLSQITAMVSLSRSMGAAIGTALFSLLL 424 + +V S + ++++ + + G A+ LL Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 52.1 bits (125), Expect = 2e-09 Identities = 40/235 (17%), Positives = 82/235 (34%), Gaps = 23/235 (9%) Query: 22 LMFFMFAMTSDAVGV-----IIPQLISEFGLSLSQASAFHYMPMIFI---AISGLFLGFL 73 L+ + + DAVG+ ++P L+ + S + + + ++ LG L Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 74 ADKIGRKLTILLGLLLFAIACFLFALGESFYYFLLLLALVGLAIGVFKTGALALIGDISR 133 +D+ GR+ +L+ L A+ + A + + + G+ A A I DI+ Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYIADIT- 124 Query: 134 STKQHSSTMNTVEGFFGVGAMVGPAIVSYLLISGVSWKYLYFGAGVFCLLLCWLAF---- 189 + + + FG G + GP + + G S +F A L Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLM--GGFSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 190 ------RADYPQVKRSSTETINLTNTFSMMKNPYALGFSL-AIGLYVATEVAIYV 237 R + + + +++ A+ F + +G A I+ Sbjct: 183 ESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG 237
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 37.2 bits (86), Expect = 2e-04 Identities = 59/276 (21%), Positives = 100/276 (36%), Gaps = 67/276 (24%) Query: 411 DDTSVTLGYYNATQ-NINMT----WMWNSYLMEVKGDNAALLDVVAADGTAYSDAGLYGY 465 D T + +G+ TQ N +T W +N +G+ A +A G + D G + Y Sbjct: 53 DQTYMRVGFKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDY 112 Query: 466 GVPYWGNCCQRNYDTEYNIKAPYLAVASSFGDLSLDASVRYDSGDASGY----------- 514 G RNY Y+++ + + FG S + Y +G A+G Sbjct: 113 G---------RNYGVLYDVEG-WTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGL 162 Query: 515 -----YAGNVQSQVDMNLDGVISIPEQSVSSIDNANPQPVNYDWSYTSYSLGANYQFDSD 569 +A Q + + ++I + ++ D+ N D + + Y Sbjct: 163 VDGLNFALQYQGKNESQSADDVNIGTNNRNNGDDIRYD--NGD----GFGISTTYDIGMG 216 Query: 570 LAAFGRLSHGGRANADRLLFGKVRADGSVAKEDAVDNVDQYELGVKYRYDDLSVFATAFY 629 +A + R N +++ G A G D D + G+KY D +++ Y Sbjct: 217 FSAGAAYTTSDRTN-EQVNAGGTIAGG--------DKADAWTAGLKY--DANNIYLATMY 265 Query: 630 SET-------------------EEQNFEATSQRFFD 646 SET + QNFE T+Q FD Sbjct: 266 SETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQFD 301
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 28.5 bits (63), Expect = 0.019 Identities = 12/30 (40%), Positives = 16/30 (53%) Query: 205 LRKLLKQTYDLPKSHFYTSSYWKIGCNEGE 234 +R L Q + L +S T YWKI N+G Sbjct: 173 IRHQLTQIHGLYRSSDKTGGYWKITMNDGS 202
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 43.6 bits (103), Expect = 1e-06 Identities = 23/56 (41%), Positives = 31/56 (55%), Gaps = 8/56 (14%) Query: 348 LAGLTLNAAKALGIEENVGSLVVGKQADFCLWDIATPAQLAYSYGVNPCKDVVKNG 403 +A T+N A A G+ +GSL VGK+AD LW+ PA +GV P V+ G Sbjct: 406 IAKYTINPAIAHGLSHEIGSLEVGKRADLVLWN---PAF----FGVKP-DMVLLGG 453 Score = 31.6 bits (72), Expect = 0.007 Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 6/61 (9%) Query: 23 YGAITNAAIAVKDGKIAWLGPRSE---LPAFDVL---SIPVYRGKGGWITPGLIDAHTHL 76 + I A I +KDG+IA +G P ++ V G+G +T G +D+H H Sbjct: 80 HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHF 139 Query: 77 V 77 + Sbjct: 140 I 140
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 50.2 bits (120), Expect = 2e-08 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 16/101 (15%) Query: 8 HVDHGKSTLIRALT---------------GMNTDRLPEEKRRGMTIDLGYAFMPLRDGTR 52 HVD GK+TL +L TD E++RG+TI G + T+ Sbjct: 11 HVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSF-QWENTK 69 Query: 53 LAFIDVPGHEKFINNMLVGVSHVRHALLVLACDDGVMPQTR 93 + ID PGH F+ + +S + A+L+++ DGV QTR Sbjct: 70 VNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTR 110
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 83.0 bits (205), Expect = 2e-19 Identities = 55/199 (27%), Positives = 92/199 (46%), Gaps = 5/199 (2%) Query: 13 VNVGTIGHVDHGKTTLTAAI--SHVLAKTYGGEAKDFSQIDNAPEERERGITINTSHIEY 70 +N+G + HVD GKTTLT ++ + G K ++ DN ER+RGITI T + Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSF 63 Query: 71 DTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVPF 130 +D PGH D++ + + +DGAIL++++ DG QTR R++G+P Sbjct: 64 QWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP- 122 Query: 131 IIVFMNKCDMVDDAELLELVEMEVRELLSEYDFPGDDLPVIQGSALKALEGEPEWEAKII 190 I F+NK D L V +++E LS + + + +W+ I Sbjct: 123 TIFFINKIDQN--GIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIE 180 Query: 191 ELAEALDSYIPEPERDIDK 209 + L+ Y+ + + Sbjct: 181 GNDDLLEKYMSGKSLEALE 199
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 118 bits (297), Expect = 8e-38 Identities = 63/125 (50%), Positives = 90/125 (72%), Gaps = 2/125 (1%) Query: 1 MTTNTENQ--TNSLDIVKWGLAILLLAAAVIGNQMYSETSAVIRALAVIVAFAIAGFIAL 58 M+ NTE Q L+ +KW + + LL A++GN +Y + +RALAV++ A AG +AL Sbjct: 1 MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLRALAVVILIAAAGGVAL 60 Query: 59 QTEKGKKALAFARESQIEVRKVVWPTRQEALNTTFIVLAATGILALVLWGLDAVLMHIVN 118 T KGK +AFARE++ EVRKV+WPTRQE L+TT IV A T +++L+LWGLD +L+ +V+ Sbjct: 61 LTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVS 120 Query: 119 FITGV 123 FITG+ Sbjct: 121 FITGL 125
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 602 bits (1554), Expect = 0.0 Identities = 172/680 (25%), Positives = 295/680 (43%), Gaps = 71/680 (10%) Query: 9 RYRNIGICAHVDAGKTTTTERVLFYTGLSHKIGEVHDGAATTDWMVQEQERGITITSAAV 68 + NIG+ AHVDAGKTT TE +L+ +G ++G V G TD + E++RGITI + Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TTFWRGMDAQFTEHRINIIDTPGHVDFTIEVERSLRVLDGAVVVFCGSSGVEPQSETVWR 128 + W ++NIIDTPGH+DF EV RSL VLDGA+++ GV+ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QADKYRVPRLVFVNKMDRAGADFERVVKQIRTRLGATCVPIQLNIGAEENFTGVIDLIKM 188 K +P + F+NK+D+ G D V + I+ +L A V Q V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNM 164 Query: 189 KAINWNEADQGMTFTYEEIPASLAAKAAEMHEYLVEAAAEASDELMDKYLEEGTLSEDEI 248 N+ E++Q + E +D+L++KY+ +L E+ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 KKALRQRTINNEIVLATCGSAFKNKGVQAVLDAVVEFLPAPVDVPPIKGIDDDEQEVERP 308 ++ R N + GSA N G+ +++ + + Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 SDDNAPFAALAFKIATDPFVGTLTFIRVYSGVLESGSGVYNSVKQKRERIGRIVQMHAND 368 + FKI L +IR+YSGVL V S K+K +I + + Sbjct: 244 -RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGE 301 Query: 369 RTELKEVRAGDIAAAIG--LK-EVTTGDTLCDPDHKVILERMEFPEPVITIAVEPKSKAD 425 ++ + +G+I LK GDT P ER+E P P++ VEP Sbjct: 302 LCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQR----ERIENPLPLLQTTVEPSKPQQ 357 Query: 426 QDKMGIALQKLAAEDPSFRVETDEESSQTLISGMGELHLDIIVDRMRREFGVECNVGKPQ 485 ++ + AL +++ DP R D + + ++S +G++ +++ ++ ++ VE + +P Sbjct: 358 REMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPT 417 Query: 486 VAYRETIRASVEAEGKFVRQSGGRGQFGHVWLKLEPNEEGAGYEFINAIVGGVVPREFIP 545 V Y E R +AE + + + L + P G+G ++ +++ G + + F Sbjct: 418 VIYME--RPLKKAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQN 475 Query: 546 AVDKGIQEQMKNGVLAGFPVLDVKVTLFDGSYHDVDSNEMAFKIAGSMGFKKGALEANPV 605 AV +GI+ + G L G+ V D K+ G Y+ S F++ + ++ +A Sbjct: 476 AVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTE 534 Query: 606 LLEPCMKVEVTTPENYMGDVVGDLNRRRGLIEGMDDGFGGIKIVHAVVPLSEMFGYATDL 665 LLEP + ++ P+ Y+ D + I I+ +P + Y +DL Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLK-NNEVILSGEIPARCIQEYRSDL 593 Query: 666 RSATQGRASYSMEFLKYSDA 685 T GR+ E Y Sbjct: 594 TFFTNGRSVCLTELKGYHVT 613
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 83.0 bits (205), Expect = 3e-19 Identities = 55/199 (27%), Positives = 91/199 (45%), Gaps = 5/199 (2%) Query: 13 VNVGTIGHVDHGKTTLTAAI--SHVLAKTYGGEAKDFSQIDNAPEERERGITINTSHIEY 70 +N+G + HVD GKTTLT ++ + G K ++ DN ER+RGITI T + Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSF 63 Query: 71 DTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVPF 130 +D PGH D++ + + +DGAIL++++ DG QTR R++G+P Sbjct: 64 QWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP- 122 Query: 131 IIVFMNKCDMVDDAELLELVEMEVRELLSEYDFPGDDLPVIQGSALKALEGEPEWEAKII 190 I F+NK D L V +++E LS + + + +W+ I Sbjct: 123 TIFFINKIDQN--GIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIE 180 Query: 191 ELAAALDSYIPEPERDIDK 209 L+ Y+ + + Sbjct: 181 GNDDLLEKYMSGKSLEALE 199
>PF06872#EspG protein Length = 398 Score = 26.6 bits (58), Expect = 0.018 Identities = 11/30 (36%), Positives = 17/30 (56%) Query: 75 PVTGKADRVGFRFEDGKKVRFFKSNSELVK 104 P + RV +F DG +R +NSEL++ Sbjct: 87 PAHNELGRVYAKFSDGSSLRISVTNSELIE 116
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 464 bits (1196), Expect = e-164 Identities = 180/428 (42%), Positives = 258/428 (60%), Gaps = 14/428 (3%) Query: 16 SELKARLLFVIGAIIVFRAGSFVPIPGIDAAVLAELFAQQKGT--ILGMFNMFSGGALSR 73 +L+ +LLF + I+V+R G+ +PIPG+D + + + G + G+ NMFSGGAL + Sbjct: 12 PDLRKKLLFTLAIIVVYRVGTHIPIPGVDYKNVQQCVREASGNQGLFGLVNMFSGGALLQ 71 Query: 74 ASIFALGIMPYISASIIMQLLTVVHPALAELKKEGESGRKKISQYTRWGTLVLGTFQSIG 133 +IFALGIMPYI+ASII+QLLTVV P L LKKEG++G KI+QYTR+ T+ L Q G Sbjct: 72 ITIFALGIMPYITASIILQLLTVVIPRLEALKKEGQAGTAKITQYTRYLTVALAILQGTG 131 Query: 134 IATGLPN--------LVPGLVVNIGFGFYFVAVVSLVTGTMFLMWLGEQITERGIGNGIS 185 + + + +V + V+ + GT +MWLGE IT+RGIGNG+S Sbjct: 132 LVATARSAPLFGRCSVGGQIVPDQSIFTTITMVICMTAGTCVVMWLGELITDRGIGNGMS 191 Query: 186 ILIFAGIVAGLPSAIGQTAEQARQGDLNVLVLLLLAVIIFAVTYFVVFVERGQRRIVVNY 245 IL+F I A PSA+ +Q + ++AV + + VVFVE+ QRRI V Y Sbjct: 192 ILMFISIAATFPSALWAIKKQGTLAGGWIEFGTVIAVGLI-MVALVVFVEQAQRRIPVQY 250 Query: 246 AKRQQGRKVFAAQSTHLPLKINMAGVIPPIFASSIILFPGTLAQWFGQNESMSWLSDFSL 305 AKR GR+ + ST++PLK+N AGVIP IFASS++ P +AQ+ G N + +L Sbjct: 251 AKRMIGRRSYGGTSTYIPLKVNQAGVIPVIFASSLLYIPALVAQFAGGNSGWKSWVEQNL 310 Query: 306 AVSPGQPLYSLLYAAAIIFFCFFYTALVFNPRETADNLKKSGAFIPGIRPGEQTSRYIDK 365 P+Y + Y I+FF FFY A+ FNP E ADN+KK G FIPGIR G T+ Y+ Sbjct: 311 T-KGDHPIYIVTYFLLIVFFAFFYVAISFNPEEVADNMKKYGGFIPGIRAGRPTAEYLSY 369 Query: 366 VMTRLTLAGALYITFICLIPEFMLIAWKV--QFYFGGTSLLIMVVVIMDFMAQVQTHMMS 423 V+ R+T G+LY+ I L+P L+ + F FGGTS+LI+V V ++ + Q+++ + Sbjct: 370 VLNRITWPGSLYLGLIALVPTMALVGFGASQNFPFGGTSILIIVGVGLETVKQIESQLQQ 429 Query: 424 HQYESVMK 431 YE ++ Sbjct: 430 RNYEGFLR 437
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.5 bits (79), Expect = 6e-05 Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 2/65 (3%) Query: 69 EHAEIKSMRTAATYKQQGIASKVLQHLINDAKAAGVQRLSLETGSMAFFQPARRLYCKFG 128 +A I+ + A Y+++G+ + +L I AK L LET + A Y K Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINI--SACHFYAKHH 145 Query: 129 FEICG 133 F I Sbjct: 146 FIIGA 150
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 105 bits (263), Expect = 1e-29 Identities = 70/248 (28%), Positives = 113/248 (45%), Gaps = 15/248 (6%) Query: 5 VLVTGSSRGIGKAITLKLAAAGYDIALHYHSNQAAADASAAELSALGVNVSLLKFDVADR 64 +TG+++GIG+A+ LA+ G IA N + + L A + DV D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 65 AAVKAAIEADIEANGAYYGVILNAGINRDNAFPAMSETEWDSVIHTNLDGFYNVIHPCVM 124 AA+ G ++ AG+ R ++S+ EW++ N G +N V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS-VS 128 Query: 125 PMVQGRKGGRIITLASVSGIAGNRGQVNYSASKAGLIGATKALSLELAKRKITVNCIAPG 184 + R+ G I+T+ S Y++SKA + TK L LELA+ I N ++PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 185 LIETDM----------VADIPKDMVEQL---VPMRRMGKPNEIAALAAFLMSDDAAYITR 231 ETDM + K +E +P++++ KP++IA FL+S A +IT Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 232 QVISVNGG 239 + V+GG Sbjct: 249 HNLCVDGG 256
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 31.0 bits (70), Expect = 0.004 Identities = 16/61 (26%), Positives = 29/61 (47%), Gaps = 11/61 (18%) Query: 137 VYDGNTLSSEQSLLLGDEFKAEYLMAMMQLIYWPEQSIKSHLEGGELVTGLCDAIPCRQF 196 +YD N LS D + +L A++ L+ + I + + G +L++ + AIP Sbjct: 63 IYDSNFLSQ-------DSERENFLQAIIILL----KRINNTISGKQLLSLISTAIPFPYG 111 Query: 197 Y 197 Y Sbjct: 112 Y 112
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 39.8 bits (93), Expect = 5e-05 Identities = 37/187 (19%), Positives = 69/187 (36%), Gaps = 26/187 (13%) Query: 656 EDIAALKARFAEDPQVQLIDKVADISTVMGHYRLLTLKLLGLALVIALLLFSLSFGVKRA 715 +A L+ F + + + D + + +K L A+++ L+ L RA Sbjct: 308 AKLAELQPFFPQGMK---VLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRA 364 Query: 716 ALVV--AVPALAALLTLAILGLVGSPLSLFHALALILVFGIGIDYS-------------- 759 L+ AVP + L T AIL G ++ ++L G+ +D + Sbjct: 365 TLIPTIAVP-VVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMED 423 Query: 760 -LFFVSAEQHG-KAVMMAVFMSACSTLLAFGLLAFSQTQA---IHYFGLTLSLGIGFTFV 814 L A + + A+ A F +AF F +T+ + + + Sbjct: 424 KLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVL 483 Query: 815 LSPLILT 821 ++ LILT Sbjct: 484 VA-LILT 489 Score = 34.8 bits (80), Expect = 0.002 Identities = 23/117 (19%), Positives = 44/117 (37%), Gaps = 17/117 (14%) Query: 694 LLGLA-LVIALLLFSLSFGVKRAALVVAVPALAALLTLAILGLVGSPLSLFHALALILVF 752 L+ ++ +V+ L L +L V+ V L + L L ++ + L+ Sbjct: 875 LVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTI 934 Query: 753 GIGIDYSLFFVS-----AEQHGKAVMMAV-----------FMSACSTLLAFGLLAFS 793 G+ ++ V E+ GK V+ A M++ + +L LA S Sbjct: 935 GLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAIS 991
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 88.1 bits (218), Expect = 5e-23 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 12/118 (10%) Query: 77 NVLFPNDSAYIAPEYYPQIEEIAMFLRQY--PTTKVTIEGHTSRTGTDERNAVLSQERAD 134 +VLF + A + PE ++++ L V + G+T R G+D N LS+ RA Sbjct: 220 DVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQ 279 Query: 135 AVTAVLADRFSIDRSRLTAIGYGSSRPLVLEHTPDAETR---------NRRVVAEVTG 183 +V L + I +++A G G S P+ + + R +RRV EV G Sbjct: 280 SVVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKG 336
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 313 bits (804), Expect = e-104 Identities = 92/432 (21%), Positives = 198/432 (45%), Gaps = 11/432 (2%) Query: 29 RLIIWALAAMVVCFLLWAGFAQLDKVTTGSGKVIPSSQVQVIQSLDGGIMQELYVREGDI 88 RL+ + + +V + + Q++ V T +GK+ S + + I+ ++ I++E+ V+EG+ Sbjct: 58 RLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGES 117 Query: 89 VTKGQPLVRIDDTRFRSDFAQQEQEVFGLKTNVIRMRAELDSILISDMTSDWREQVKITK 148 V KG L+++ +D + + + + R + SI E K+ + Sbjct: 118 VRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSI----------ELNKLPE 167 Query: 149 KALVFPESLTEAEPALVKRQQEEYNGRLDNLSNQLEILVRQIQQRQQEIDDLASKTTTLT 208 L V R + NQ + +++ E + ++ Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 209 TSMQLISRELELTRPLAKKGIVPEVELLKLERAVNDAQGELNSLRLLRPKLKAALDEAIL 268 ++ L+ L K + + +L+ E +A EL + ++++ + A Sbjct: 228 NLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287 Query: 269 KRREAVFVYAADLRAQLNETQTRLSRMNEAQVGAQDKVSKAIITSPVNGTIKSVHINTLG 328 + + ++ ++ +L +T + + +++ ++I +PV+ ++ + ++T G Sbjct: 288 EYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEG 347 Query: 329 GVVQPGVDIVEIVPSEDQLLIETKILPKDIAFLHTGLPAVVKVTAYDFTRYGGLKGTVEH 388 GVV ++ IVP +D L + + KDI F++ G A++KV A+ +TRYG L G V++ Sbjct: 348 GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKN 407 Query: 389 ISADTSQDEEGNSFYLIKVRTEESSLVKDDGTQMPIIPGMLTTVDVITGQRSILEYILNP 448 I+ D +D+ + + + EE+ L +P+ GM T ++ TG RS++ Y+L+P Sbjct: 408 INLDAIEDQRLGLVFNVIISIEENCLS-TGNKNIPLSSGMAVTAEIKTGMRSVISYLLSP 466 Query: 449 ILRAKDTALRER 460 + + +LRER Sbjct: 467 LEESVTESLRER 478
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 71.5 bits (175), Expect = 4e-14 Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 9/124 (7%) Query: 5248 DTVNLGEGDDTVYGGEGTQMVYGGAGNDLLIGGAGIDGLRGGDGNDTLIGGLGDDVLRGD 5307 ++ G + GG G ++ G + +++L GGAG D L GG G DTL GG G D Sbjct: 332 VSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYG 391 Query: 5308 GGSDTFVWRYADADQGTDHIMDFNVREDKLDLSDLLQGETANTLESYLKFSLDNGSTVID 5367 G D+ V D I DF DK+DLS +F+ ++ Sbjct: 392 SGQDSTV-------AAYDWIADFQKGIDKIDLSAF--RNEGQLSFVQDQFTGKGQEVMLQ 442 Query: 5368 IDAN 5371 DA Sbjct: 443 WDAA 446
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 332 bits (854), Expect = e-117 Identities = 167/304 (54%), Positives = 205/304 (67%), Gaps = 15/304 (4%) Query: 5 ISLLSHSLAQSPWLFIALSFVFAATIGSFLNVVIHRFPVMMKREWQQECNQYLQEYHVDV 64 ++LL PWL+ +L F+F+ IGSFLNVVIHR P+M++REWQ E Y Sbjct: 1 MALLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPD---- 56 Query: 65 VKQIGIEKLNKPIDTYPEKYNLVVPGSACPKCKTAIKPWHNLPIVGWLMLRGKCAACDAP 124 YNL+VP S CP C I N+P++ WL LRG+C C AP Sbjct: 57 -----------DEGVDEPPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAP 105 Query: 125 ISSRYPIIELVTGLLVATLAWHFGPSWQFVFAAVLTFVLIALTGIDLDEMLLPDQMTLPL 184 IS+RYP++EL+T LL +A P W + A +LT+VL+ALT IDLD+MLLPDQ+TLPL Sbjct: 106 ISARYPLVELLTALLSVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPL 165 Query: 185 LWLGLLINLNHTFTTPTDAVIGAAAGYLSLWSVFWLFKLLTGKEGMGYGDFKLLAVFGAW 244 LW GLL NL F + DAVIGA AGYL LWS++W FKLLTGKEGMGYGDFKLLA GAW Sbjct: 166 LWGGLLFNLLGGFVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAW 225 Query: 245 LGWQMLPLVILLSSLVGALVGITLIVLKRNQLANPIPFGPYIAAAGWIALIWGQPIVDWY 304 LGWQ LP+V+LLSSLVGA +GI LI+L+ + + PIPFGPY+A AGWIAL+WG I WY Sbjct: 226 LGWQALPIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWY 285 Query: 305 LSTL 308 L+ Sbjct: 286 LTNF 289
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 391 bits (1006), Expect = e-136 Identities = 117/405 (28%), Positives = 211/405 (52%), Gaps = 10/405 (2%) Query: 25 TFEWKGLNRDGKKTGGELKGTSVAEVKSQLKLQGVNPKVVRKK---------ASPLFAHN 75 + ++ L+ GKK G + S + + L+ +G+ P V + Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 76 PDIKPMDIAMVTRQIATMLAAGVPLVTTIEMLGRGHEKQKMRELLGTILSEVQSGIPLSD 135 + D+A++TRQ+AT++AA +PL ++ + + EK + +L+ + S+V G L+D Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 136 SLRPHRRYFDDLYVDLVAAGEHSGSLDAVFDRIATYREKAEALKSKIKKAMFYPAAVVVV 195 +++ F+ LY +VAAGE SG LDAV +R+A Y E+ + ++S+I++AM YP + VV Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 196 AIAVTTLLLLFVVPQFESIFASFGAELPAFTQMIVGISRFLQSSWYIFFAAIAISIWLFV 255 AIAV ++LL VVP+ F LP T++++G+S +++ + + ++ ++ Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRT-FGPWMLLALLAGFMAF 241 Query: 256 RAHRNSQMFRDRIDELVLKIPIIGEILHKAAMARFSRTLATTFAAGVPLIDGMESAAGAS 315 R + R +L +P+IG I AR++RTL+ A+ VPL+ M + Sbjct: 242 RVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVM 301 Query: 316 GNAVYRSALLKVRQEVMAGMQMNVAMRTTGLFPDMLIQMVMIGEESGSLDSMLNKVANIY 375 N R L V G+ ++ A+ T LFP M+ M+ GE SG LDSML + A+ Sbjct: 302 SNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQ 361 Query: 376 EMQVDDAVDGLSSLIEPIMMVVIGILVGGLIVGMYLPIFQMGNVV 420 + + + L EP+++V + +V +++ + PI Q+ ++ Sbjct: 362 DREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 48.3 bits (115), Expect = 3e-10 Identities = 21/60 (35%), Positives = 35/60 (58%), Gaps = 5/60 (8%) Query: 1 MKATNQTLNKKAQGFTLIELMIVVAIIGILAAIALPAYKEYVNKSKINSCLSEASAWTKA 60 M+AT+ K +GFTL+E+M+V+ IIG+LA++ +P K+ +S+ A A Sbjct: 1 MRATD-----KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENA 55
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 76.2 bits (187), Expect = 2e-18 Identities = 49/184 (26%), Positives = 80/184 (43%), Gaps = 2/184 (1%) Query: 3 GLTGKVVIITGASEGIGRALAIAMARVGCQLVLSARNETRLASLALEIANYGPTPFVFAA 62 G+ GK+ ITGA++GIG A+A +A G + N +L + + F A Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 63 DVSSASQCEALIQATIVHYGRLDILVNNAGMTMWSRFDELNQLSVLEDIMRVNYLGPAYL 122 DV ++ + + G +DILVN AG+ L+ E VN G Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEW-EATFSVNSTGVFNA 123 Query: 123 THAALPYLKSSQ-GQVVVVASVAGLTGVPTRSGYAASKHAVIGFFDSLRIELTDDNVAVT 181 + + Y+ + G +V V S + + YA+SK A + F L +EL + N+ Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 182 VICP 185 ++ P Sbjct: 184 IVSP 187
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.5 bits (74), Expect = 0.003 Identities = 53/286 (18%), Positives = 101/286 (35%), Gaps = 30/286 (10%) Query: 15 LFVPVTGLSLFALASGYLMSLIPLSLSYFELSPDLAP---WLASIFYLGLLLGAPCIAPI 71 L V ++ ++L A+ G +M ++P L S D+ L +++ L AP + + Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 72 VARIGHSKAFILFLNILLCSVVVMVLLPQGGIWL--ASRLVAGVAVAGIFVVVESWLLMA 129 R G + +L +++ +V ++ +W+ R+VAG+ A V +++ Sbjct: 67 SDRFG--RRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYIADI 123 Query: 130 DTQKQRAKRLGLYMTALYG-GTAIGQLAVDYLGTTGNLPYLVVIGLLAAASLPALLVKRG 188 +RA+ G +M+A +G G G + +G L + Sbjct: 124 TDGDERARHFG-FMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 189 QPQSSEQHSIALSDLKNLSKPAVVGCLVSGLLLGPIYGLLPVYVSQDMGFAQQTGQFMAL 248 + E+ + L L+ + + L+ V+ Q GQ A Sbjct: 183 ESHKGERRPLRREALNPLAS------FRWARGMTVVAALMAVFFI-----MQLVGQVPAA 231 Query: 249 IIMGGMIVQPLVSYLSPRFQKSALMAAFCLIGAAALFLLTQKSLVG 294 + V + RF A L L L Q + G Sbjct: 232 L---------WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITG 268
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 70.4 bits (172), Expect = 4e-18 Identities = 39/96 (40%), Positives = 51/96 (53%), Gaps = 2/96 (2%) Query: 12 GEGKEAVKGALITTQYRGFLQDGTQFDSSYDRGQAFQCVIGTGRVIKGWDQGLMGMKVGG 71 G G + K +T +Y G L DGT FDS+ G+ +VI GW + L M G Sbjct: 136 GTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKP--ATFQVSQVIPGWTEALQLMPAGS 193 Query: 72 KRKLFVPAHLAYGERQIGAHIKPNSDLTFEIELLEV 107 ++FVPA LAYG R +G I PN L F+I L+ V Sbjct: 194 TWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISV 229
>SECA#SecA protein signature. Length = 901 Score = 49.5 bits (118), Expect = 1e-08 Identities = 15/20 (75%), Positives = 18/20 (90%) Query: 2 KLGRNDPCHCGSGKKFKRCC 21 K+GRNDPC CGSGKK+K+C Sbjct: 878 KVGRNDPCPCGSGKKYKQCH 897
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.012 Identities = 13/100 (13%), Positives = 30/100 (30%), Gaps = 5/100 (5%) Query: 220 AEKDTLLRTLFEQGLLTRHQALALTRKESANTDETYQYWLTPDLITPYIQQAQSQLQQEQ 279 + +L + + +H L K +E Y + I I A+ + Q Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 280 AEALAKKLAIEKAEKEKMLTDIYNQREHSWQQAQEQANRT 319 K ++K + + + +E+ + Sbjct: 294 QL--FKNEILDKLRQTTDNIGLLTLEL---AKNEERQQAS 328
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.7 bits (74), Expect = 0.001 Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 2/80 (2%) Query: 145 PMAYDDTPVAVSPPVRVTTSMQYSPSEGRMVSNMPTNSATVISQTGASTARASTASAEQI 204 P + +T P + T+S P N NS + T ++E Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVN-TGNSVVENPENTTPATTQPTVNSES- 1215 Query: 205 ANVPRARAARSVSSLPSNAR 224 +N P+ R RSV S+P N Sbjct: 1216 SNKPKNRHRRSVRSVPHNVE 1235
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 52.1 bits (125), Expect = 2e-09 Identities = 61/322 (18%), Positives = 107/322 (33%), Gaps = 22/322 (6%) Query: 50 VAHVSYAISAYALGVVVGSPIIMVLGVRIKRRTLLIALAAMMAVANGLSALAPSLNWLVF 109 AH ++ YAL +P++ L R RR +L+ A AV + A AP L L Sbjct: 42 TAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYI 101 Query: 110 FRFLSGLPHGAYFGVAMLLAASLVPPDMKARAVSRVIIGLTLATIVGVPFATWMGQTVGW 169 R ++G+ GA VA A + D +AR + + G MG Sbjct: 102 GRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSP 159 Query: 170 RSGIGIVAIIAAVTAVMLYFLAPNVAVPQNASPKKELQTLKNREVWLTLGIAAIGFGGIF 229 + A + + + FL P + + N + Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPE---SHKGERRPLRREALNPLASFRWARGMTVVAALM 216 Query: 230 CVYTYLAETLIQVTQV------------EPFKIPVMIAVFGI-GATLGTLVCGWAADK-S 275 V+ ++ + + QV + I + +A FGI + ++ G A + Sbjct: 217 AVF-FIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLG 275 Query: 276 ALAAAFWSLVLSTLVLALYPSLTGSYWALMPI-VFFVGSGIGLATIVQARLMDVAPDGQA 334 A ++ L + W PI V GIG+ + V + Q Sbjct: 276 ERRALMLGMIADGTGYILL-AFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQG 334 Query: 335 MTGALVQCAFNLANAIGPWVGS 356 + +L + +GP + + Sbjct: 335 QLQGSLAALTSLTSIVGPLLFT 356
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 52.4 bits (125), Expect = 2e-10 Identities = 41/183 (22%), Positives = 80/183 (43%), Gaps = 5/183 (2%) Query: 2 ILITGASSGLGAALAALYAKDNQALTLTGRDANRLHTVANALSPFSTQSISAISADLADE 61 ITGA+ G+G A+A A + + +L V ++L + + A AD+ D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHA-EAFPADVRDS 69 Query: 62 ASVEALFDGL---TDTPNTVIHCAGSGYFGALETQGTSEIQALLNNNVTSTILLVRELVK 118 A+++ + + + +++ AG G + + E +A + N T R + K Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 119 RYK-QQAVKVVVVMSTAALAAKAGESTYCAAKWAVRGFIESVRLELKQSQMKLIAVYPGG 177 +++ +V V S A + + Y ++K A F + + LEL + ++ V PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 178 MDT 180 +T Sbjct: 190 TET 192
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.007 Identities = 9/23 (39%), Positives = 11/23 (47%) Query: 126 GIVGAIWVKDGDDVAFDQPLFTL 148 IV I VK+G+ V L L Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKL 127
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.015 Identities = 21/167 (12%), Positives = 52/167 (31%), Gaps = 17/167 (10%) Query: 80 EVQAQIARQQQAELAIAAADRAVYNPEL-GLNYQNADTDTYSLGLSQTIDWGDKRGVATR 138 + + QA L + EL L + Y +S+ + + Sbjct: 135 DTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194 Query: 139 LAQLEAQILLADISLERSQMLAERLLALAEQAQSNKALTFAEQQLRFTQAQLNIAEQRFA 198 + + Q +++L++ + AE+ + E R +++L+ Sbjct: 195 FSTWQNQKYQKELNLDKKR---------AERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 199 AGDLS-----DVELQLLKL--ELASNTADYAMAEQAALVADGKVIEL 238 ++ + E + ++ EL + E L A + + Sbjct: 246 KQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLV 292
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 55.2 bits (133), Expect = 2e-10 Identities = 31/138 (22%), Positives = 56/138 (40%), Gaps = 9/138 (6%) Query: 157 EVAKAQAEYINAAAEWNRVRR---MSESAVSVSRRMQAQVDAELKRAILEAIKMTAEQIR 213 V + + +Y+ A E + ES + ++ V K IL+ ++ T + I Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 214 TLE----STPEAIGSYQLLAPIDGRVQQ-DIAMLGQVFTAGTPLMQLT-DESHLWVEAQL 267 L E + + AP+ +VQQ + G V T LM + ++ L V A + Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALV 372 Query: 268 TPAQAANVNAGGPALVQV 285 +N G A+++V Sbjct: 373 QNKDIGFINVGQNAIIKV 390 Score = 42.9 bits (101), Expect = 2e-06 Identities = 28/149 (18%), Positives = 55/149 (36%), Gaps = 5/149 (3%) Query: 101 SLSNLNLDTMATATLVVDRDRTATLAPQLDVRVQARHVVPGQEVKKGEPLLTLGG----A 156 L + + A L R+ + P + V+ V G+ V+KG+ LL L A Sbjct: 76 VLGQVEIVATANGKLTHS-GRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA 134 Query: 157 EVAKAQAEYINAAAEWNRVRRMSESAVSVSRRMQAQVDAELKRAILEAIKMTAEQIRTLE 216 + K Q+ + A E R + +S S D + + E + + + Sbjct: 135 DTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194 Query: 217 STPEAIGSYQLLAPIDGRVQQDIAMLGQV 245 + YQ +D + + + +L ++ Sbjct: 195 FSTWQNQKYQKELNLDKKRAERLTVLARI 223
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 653 bits (1686), Expect = 0.0 Identities = 224/1077 (20%), Positives = 440/1077 (40%), Gaps = 72/1077 (6%) Query: 9 AIKNRLLVVLALLAVVAASVAMLPKLNLDAFPDVTNVQVTINTAAEGLAAEEVEKLISYP 68 I+ + + + ++ A + +L + +P + V+++ G A+ V+ ++ Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 69 VESAMYALPAVTEVRSLS-RTGLSIVTVVFAEGTDIYFARQQVFEQLQAAREMIPSGVGV 127 +E M + + + S S G +T+ F GTD A+ QV +LQ A ++P V Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 128 PEIGPNTSGLGQIYQYILRADPSSGINAAELRSLNDYLVKLIMMPVGGVTDVLSFGGEVR 187 I S + +D + G ++ VK + + GV DV FG + Sbjct: 125 QGISVEKSSSSYLMVAGFVSD-NPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ-Y 182 Query: 188 QYQVQVDPNKLRAYGLSMAQVSEALESNNRNAGGWFMDQGQEQLVVRGYGMLPAGEAGLA 247 ++ +D + L Y L+ V L+ N + G L + + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLG-GTPALPGQQLNASIIAQTRFK 241 Query: 248 AIAQIPLTEVR----GTPVRVGDIAKVDFGSEIRVGAVTMTRRDEAGQAQALGEVVAGVV 303 + +R G+ VR+ D+A+V+ G E + G+ + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARIN-----GK-----PAAGLGI 291 Query: 304 LKRMGANTKATIDDIDARINLIEQALPKGVSFEVFYDQADLVDKAVTTVRDALLMAFVFI 363 GAN T I A++ ++ P+G+ YD V ++ V L A + + Sbjct: 292 KLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLV 351 Query: 364 VVILALFLVNIRATLLVLLSIPVSIGLALMVMSYYGLSANLMSLGGLAVAIGMLVDGSVV 423 +++ LFL N+RATL+ +++PV + +++ +G S N +++ G+ +AIG+LVD ++V Sbjct: 352 FLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIV 411 Query: 424 MVENIFKHLTQPDRRHLAQARSRADGEVDPYHGDEDGSVRAVEADNSMAVRIMLAAKEVC 483 +VEN+ + + + + EA + ++ Sbjct: 412 VVENVERVM-------------------------MEDKLPPKEA-------TEKSMSQIQ 439 Query: 484 SPIFFATAIIIVVFAPLFALEGVEGKLFQPMAVSIILAMISALLVALIAVPALAVYLFK- 542 + ++ VF P+ G G +++ +++I+ AM ++LVALI PAL L K Sbjct: 440 GALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKP 499 Query: 543 ---------RGVVLKESVVLVPLDSAYRKLLSATLARPKLVMISALLMFAMSMVLLPRLG 593 G + + Y + L ++ L+ A +VL RL Sbjct: 500 VSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLP 559 Query: 594 TEFVPELEEGTINLRVTLAPTASLGTSLDVAPKLEAMLLEFPEVEYALSRIGAPELGGDP 653 + F+PE ++G + L A+ + V ++ L+ + S Sbjct: 560 SSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVE-SVFTVNGFSFSG 618 Query: 654 EPVSNIEVYIGLKPIEEWQSASSRLE--LQRLMEEKLSVFPGLLLTFSQPIATRVDELLS 711 + + ++ LKP EE + E + R E + G ++ F+ P + EL + Sbjct: 619 QAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMP---AIVELGT 675 Query: 712 GVKAQLA-IKLFGPDLDVLSEKGQVLTDLVAKIPGAV-DVSLEQVSGEAQLVVRPDRSQL 769 I G D L++ L + A+ P ++ V + AQ + D+ + Sbjct: 676 ATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKA 735 Query: 770 ARYGISVDQVMSLVSQGIGGASAGQVIDGNARYDINLRLAAEYRSSPDVIKDLLLSGSNG 829 G+S+ + +S +GG ID + ++ A++R P+ + L + +NG Sbjct: 736 QALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANG 795 Query: 830 ATVRLGEVASVEVEMAPPNIRRDDVQRRVVVQANVA-GRDMGSVVKDIYELVPQADLPAG 888 V + P + R + + +Q A G G + + L + LPAG Sbjct: 796 EMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASK--LPAG 853 Query: 889 YTVIVGGQYENQQRAQQKLMLVVPISIALIALLLYFSFGAVKQVLLIMANVPLALIGGIV 948 G ++ + + +V IS ++ L L + + + +M VPL ++G ++ Sbjct: 854 IGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLL 913 Query: 949 ALFVSGTYLSVPSSIGFITLFGVAVLNGVVLVDSINQ-RRQSGESLYDSVYEGTVGRLRP 1007 A + V +G +T G++ N +++V+ + G+ + ++ RLRP Sbjct: 914 AATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRP 973 Query: 1008 VLMTALTSALGLIPILVSSGVGSEIQKPLAVVIIGGLFSSTALTLLVLPTLYRWLYR 1064 +LMT+L LG++P+ +S+G GS Q + + ++GG+ S+T L + +P + + R Sbjct: 974 ILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 109 bits (273), Expect = 4e-26 Identities = 85/550 (15%), Positives = 186/550 (33%), Gaps = 68/550 (12%) Query: 10 IKNRLLVVLALLAVVAASVAMLPKLNLDAFPDVTNVQVTIN-TAAEGLAAEEVEKLI--- 65 + + +L +VA V + +L P+ G E +K++ Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 66 -SYPVESAMYALPAVTEVRSLSRTGLS----IVTVVFAEGTDIYFARQQVFEQLQAAREM 120 Y +++ + +V V S +G + + V + + A+ Sbjct: 594 TDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKME 653 Query: 121 ---IPSGVGVPEIGPNTSGLGQIYQYILRADPSSGINAAELRSLNDYLVKLIMMPVGGVT 177 I G +P P LG + +G+ L + L+ + + Sbjct: 654 LGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLV 713 Query: 178 DVLSFGGEVR-QYQVQVDPNKLRAYGLSMAQVSEALES--NNRNAGGWFMDQGQEQLVVR 234 V G E Q++++VD K +A G+S++ +++ + + + ++L V+ Sbjct: 714 SVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQ 773 Query: 235 GYGMLPAGEA-GLAAIAQIPLTEVRGTPVRVGDIAKVDFGSEIRVGAVTMTRRDEAGQAQ 293 A + ++ + G V + G+ + R + + Sbjct: 774 ----ADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVY----GSPRLERYNGLPSME 825 Query: 294 ALGEVVAGVVLKRMGANTKATIDDIDARINLIEQALPKGVSFEVFYDQADLVDKAVTTVR 353 GE G D A + + LP G+ ++ + + + Sbjct: 826 IQGEAAPGTSS-----------GDAMALMENLASKLPAGIGYD-WTGMSYQERLSGNQAP 873 Query: 354 DALLMAFVFIVVILALFLVNIRATLLVLLSIPVSIGLALMVMSYYGLSANLMSLGGLAVA 413 + ++FV + + LA + + V+L +P+ I L+ + + ++ + GL Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTT 933 Query: 414 IGMLVDGSVVMVENIFKHLTQPDRRHLAQARSRADGEVDPYHGDEDGSVRAVEADNSMAV 473 IG+ ++++VE A+ +G+ VEA Sbjct: 934 IGLSAKNAILIVE-------------FAKDLMEKEGK------------GVVEA------ 962 Query: 474 RIMLAAKEVCSPIFFATAIIIVVFAPLFALEGVEGKLFQPMAVSIILAMISALLVALIAV 533 ++A + PI + I+ PL G + + ++ M+SA L+A+ V Sbjct: 963 -TLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFV 1021 Query: 534 PALAVYLFKR 543 P V + + Sbjct: 1022 PVFFVVIRRC 1031 Score = 98.8 bits (246), Expect = 5e-23 Identities = 66/347 (19%), Positives = 140/347 (40%), Gaps = 16/347 (4%) Query: 735 VLTDLVAKIPGAVDVSLEQVSGEAQLVVRPDRSQLARYGISVDQVMSLVSQGIGGASAGQ 794 + D ++++ G DV L + + + D L +Y ++ V++ + +AGQ Sbjct: 161 NVKDTLSRLNGVGDVQL--FGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQ 218 Query: 795 VIDGNARYDINLRLA----AEYRSSPDVIKDLLLSGSNGATVRLGEVASVEVEMAPPNIR 850 + A L + +++ + K L S+G+ VRL +VA VE+ N+ Sbjct: 219 LGGTPALPGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVI 278 Query: 851 -RDDVQRRVVVQANVA-GRDMGSVVKDIYELVP--QADLPAGYTVIVGGQYENQQRAQQK 906 R + + + +A G + K I + Q P G V+ Y+ Q Sbjct: 279 ARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLY--PYDTTPFVQLS 336 Query: 907 LMLVVP---ISIALIALLLYFSFGAVKQVLLIMANVPLALIGGIVALFVSGTYLSVPSSI 963 + VV +I L+ L++Y ++ L+ VP+ L+G L G ++ + Sbjct: 337 IHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMF 396 Query: 964 GFITLFGVAVLNGVVLVDSINQRRQS-GESLYDSVYEGTVGRLRPVLMTALTSALGLIPI 1022 G + G+ V + +V+V+++ + ++ + ++ A+ + IP+ Sbjct: 397 GMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPM 456 Query: 1023 LVSSGVGSEIQKPLAVVIIGGLFSSTALTLLVLPTLYRWLYRHDKSP 1069 G I + ++ I+ + S + L++ P L L + + Sbjct: 457 AFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAE 503
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 174 bits (443), Expect = 1e-59 Identities = 89/136 (65%), Positives = 111/136 (81%), Gaps = 1/136 (0%) Query: 1 MSLIKEFKAFASRGNVIDMAVGIIIGAAFGKIVSSFVADIIMPPIGIILGGVNFSDLSIV 60 MS+IKEF+ FA RGNV+D+AVG+IIGAAFGKIVSS VADIIMPP+G+++GG++F ++ Sbjct: 1 MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60 Query: 61 LQAAQGDAPAVVIAYGKFIQTVIDFTIIAFAIFMGLKAINSLKRKQEEAPKAPPAPTKDQ 120 L+ AQGD PAVV+ YG FIQ V DF I+AFAIFM +K IN L RK+EE P A PAPTK++ Sbjct: 61 LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE-PAAAPAPTKEE 119 Query: 121 ELLSEIRDLLKAQQEK 136 LL+EIRDLLK Q + Sbjct: 120 VLLTEIRDLLKEQNNR 135
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 94.5 bits (235), Expect = 2e-23 Identities = 38/290 (13%), Positives = 91/290 (31%), Gaps = 28/290 (9%) Query: 71 LAQLEDNQFSAKVSQAEASLGSAKADLQTLAAKVELQHALISQASAGVVAAQADKLRAEQ 130 + + + S + + + ++ + A A + + + Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Query: 131 QLTRAKKLKVSNYSSQDDVDQLQAGFDSAAAGLDEAKA--------LLVAKERELAVFN- 181 +L L ++ V + + + A L K+ +L AKE V Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 182 ------AQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAM-VGQYVQPGQA 234 +L Q + L + + + + AP S + + G V + Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Query: 235 LYSLVPDGAV-WITANFKETQIQHMQPGQSVQVSLDAFPDKTF---TGVIDSLSPASGAK 290 L +VP+ +TA + I + GQ+ + ++AFP + G + +++ + Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA--- 412 Query: 291 FSLLPAENATGNFTKIVQRIPVRIRLDLSEEEARVVPGLSAVVKVDTASH 340 + G ++ I + + G++ ++ T Sbjct: 413 ----IEDQRLGLVFNVIISIEENCLST-GNKNIPLSSGMAVTAEIKTGMR 457 Score = 57.5 bits (139), Expect = 2e-11 Identities = 24/128 (18%), Positives = 48/128 (37%), Gaps = 2/128 (1%) Query: 59 VTDNQHVRKGELLAQLEDNQFSAKVSQAEASLGSAKADLQTLAAKVELQHALISQASAGV 118 V + + VRKG++L +L A + ++SL A+ + L + Sbjct: 112 VKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR-SIELNKLPELKL 170 Query: 119 VAAQADKLRAEQQLTRAKKLKVSNYSS-QDDVDQLQAGFDSAAAGLDEAKALLVAKEREL 177 + +E+++ R L +S+ Q+ Q + D A A + E Sbjct: 171 PDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Query: 178 AVFNAQLN 185 V ++L+ Sbjct: 231 RVEKSRLD 238
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 123 bits (310), Expect = 1e-32 Identities = 89/421 (21%), Positives = 177/421 (42%), Gaps = 19/421 (4%) Query: 18 SEYERGSRRSWIAVFGGLIGAFMAILDIQITNASMKEIQGSLGATLEEGSWISTAYLVAE 77 + Y + + R + I +F ++L+ + N S+ +I +W++TA+++ Sbjct: 3 TSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTF 62 Query: 78 MIAIPLSGWLSTGLSVRRYLLWTTAAFIFASILCSISWN-LEAMIAFRALQGFFGGALIP 136 I + G LS L ++R LL+ F S++ + + +I R +QG A Sbjct: 63 SIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPA 122 Query: 137 LAFRLILEFLPENKRAVGMALFGVTATFAPSIGPTLGGWLTEHFSWHYLFYINVPPGLLV 196 L ++ ++P+ R L G +GP +GG + + W YL +P ++ Sbjct: 123 LVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITII 180 Query: 197 MAMLAYGLEKRPVVWDKLKNADLAGIVTMALGMGCLEVVLEEGNRKDWFGSDLIRNLAII 256 L K+ V + D+ GI+ M++G+ + F + + I+ Sbjct: 181 TVPFLMKLLKKEVRIKG--HFDIKGIILMSVGIVFFML----------FTTSYSISFLIV 228 Query: 257 AAVNLVLFVWIQLKRKDPLVNLRLLGKRDFVLSTIAYFLLGMALFGAIYLIPLYLSQVHD 316 + ++ ++FV K DP V+ L F++ + ++ + G + ++P + VH Sbjct: 229 SVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQ 288 Query: 317 YTPLEIGEVIMWMGFPQLLVL-PLVPRLMQRFDGRYLAAFGFFMFALSYYMNSQMTADYA 375 + EIG VI++ G +++ + L+ R Y+ G ++S+ S + Sbjct: 289 LSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL--LET 346 Query: 376 GPQMIASQVVRALG-QPFILVPIGMLATAHLKPHENPSASTVLNVMRNLGGAFGIALVAT 434 + +V LG F I + ++ LK E + ++LN L GIA+V Sbjct: 347 TSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGG 406 Query: 435 L 435 L Sbjct: 407 L 407
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 43.0 bits (101), Expect = 8e-08 Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 5/72 (6%) Query: 81 ASIGRVVVSPAGRGKGLAMPLMQRAIDAALSTWPAAGIQIGAQDYLKS---FYQKLGFSA 137 A I + V+ R KG+ L+ +AI+ A G+ + QD S FY K F Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKEN-HFCGLMLETQDINISACHFYAKHHFII 148 Query: 138 CS-DMYLEDGIP 148 + D L P Sbjct: 149 GAVDTMLYSNFP 160
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 30.2 bits (68), Expect = 0.027 Identities = 41/161 (25%), Positives = 64/161 (39%), Gaps = 17/161 (10%) Query: 420 FSRRGRELINTQRQLSENRALLEHAQRIAIAGELGASLSHELNQPLAAIGHYCHGAEVRL 479 FS R +EL +R+LS+++A + + + S EL Q + L Sbjct: 60 FSER-KELSLDKRKLSDSQARV--SDVEEQVNQYL-SKVPELEQK-QNVSELLS----LL 110 Query: 480 QRGTRPE--ELQAVLNLIQQEVSRADSIISRLRNLLKKRPVSKQPLYLHQLVNDTAPLLA 537 +L+A L +E S ++ LR+ LK RP L LV L++ Sbjct: 111 SNSPNISLSQLKAYLEGKSEEPSEQFKMLCGLRDALKGRPELAH---LSHLVEQA--LVS 165 Query: 538 YELEQ-HQIQLSTNISGEAYQLPLDEVGMQQLLLNLLKNAA 577 EQ I L I+ EAY+ V Q L + ++A Sbjct: 166 MAEEQGETIVLGARITPEAYRESQSGVNPLQPLRDTYRDAV 206
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.8 bits (241), Expect = 1e-25 Identities = 28/123 (22%), Positives = 52/123 (42%) Query: 7 VYLIDDDESVRRSLRFMLESYGLNIHDFDSAEAFFAAIDLSEPGCALVDVRMPGLSGPQL 66 + + DDD ++R L L G ++ +A + I + + DV MP + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 67 HAQLVQHNSPLAVIYLTGHGDVPMAVEALKLGAVDFFQKPADGAKLADAVVKALEHAKAY 126 ++ + L V+ ++ A++A + GA D+ KP D +L + +AL K Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 127 HQN 129 Sbjct: 126 PSK 128
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 53.1 bits (127), Expect = 5e-09 Identities = 53/316 (16%), Positives = 101/316 (31%), Gaps = 10/316 (3%) Query: 598 EYAASEQELRIRLSKAEEALQSAQELQAEAESQLVAINGELDKLSRELTFARTAYKNSRD 657 EL LS A+E L+ + +E S++ + L + L A Sbjct: 82 ALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSA 141 Query: 658 DLRRLFDEKRSEQDKINKALAERKAFAQQRLTQLDGELKQLKHQHQLWLEEQKEQALEAR 717 ++ L EK + KA K + + E ++ LE Sbjct: 142 KIKTLEAEK---AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA 198 Query: 718 MEKQAYWQEVIGALDNQLGQIKATIDARRESAKAEQKACETWYKNELKSRGVDEDNILKL 777 +E + A L KA + AR+ + + + + E L Sbjct: 199 LEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 258 Query: 778 KQQIRELETKISRAEQRRSEVLRFDDWY-----QHTWLLRKPKLQTQLSDVKR-AASEID 831 + + ELE + A + + Q+Q+ + R + Sbjct: 259 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDL 318 Query: 832 QQLKAKTQEVKTRRQQLETDRKASDAAQIEASENLTKLRAVMRKLAELKLPANNEEAQGS 891 + ++++ Q+LE K S+A++ +L R ++L E + E+ + S Sbjct: 319 DASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQL-EAEHQKLEEQNKIS 377 Query: 892 LGERLRQGEDLLLKRD 907 R DL R+ Sbjct: 378 EASRQSLRRDLDASRE 393 Score = 34.3 bits (78), Expect = 0.004 Identities = 49/346 (14%), Positives = 114/346 (32%), Gaps = 27/346 (7%) Query: 360 WRADMENLSERHKLQTEKHQDIEAAYNARRSKIGEQLNRELEGLHADQDKQREARDKQRE 419 + + + K+ D+ A + N EL ++ ++ DK Sbjct: 55 VQERADKFEIENNTLKLKNSDLSFNNKAL-----KDHNDELTEELSNAKEKLRKNDKSLS 109 Query: 420 VARADLDALEAQWRSQMDAGKASFSEQEYQFKLNAAELKLRVDGVTYTEEEKLSLAIFDE 479 + + LEA + D KA + +A L + + ++ Sbjct: 110 EKASKIQELEA---RKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL----EK 162 Query: 480 RIHRADEEQESCNAKVERLSSDERKLRAKRDQANEALRIASLRVNERQTALDELHHMLFP 539 + A + +AK++ L +++ L A++ + +AL A + L Sbjct: 163 ALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA 222 Query: 540 QSHTL--LEFLRKEAQGWEQSLGKVIAPELLHRTDLHPSVTGTSDTLFGVHLDLKAIDVP 597 + LE + A + + I + L + Sbjct: 223 LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA------------LE 270 Query: 598 EYAASEQELRIRLSKAEEALQSAQELQAEAESQLVAINGELDKLSRELTFARTAYKNSRD 657 ++ E + + +A+ E Q +N L R+L +R A K Sbjct: 271 GAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEA 330 Query: 658 DLRRLFDEKRSEQDKINKALAERKAFAQQRLTQLDGELKQLKHQHQ 703 + ++L ++ + + ++L +++ QL+ E ++L+ Q++ Sbjct: 331 EHQKLEEQNKI-SEASRQSLRRDLDASREAKKQLEAEHQKLEEQNK 375
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 31.3 bits (71), Expect = 0.003 Identities = 19/83 (22%), Positives = 35/83 (42%), Gaps = 6/83 (7%) Query: 1 MRALALSAV-LMVTTMIGMPAVAKEWQENKSWNAHFSEHKTQGVVVLWNENTQQGFTNDL 59 MR + L + L+ T + + A + ++ K + S G++ + + G T Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRV--GMIEM---DLASGRTLTA 55 Query: 60 KRANQAFLPASTFKIPNSLIALD 82 RA++ F STFK+ L Sbjct: 56 WRADERFPMMSTFKVVLCGAVLA 78
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 540 bits (1393), Expect = 0.0 Identities = 180/689 (26%), Positives = 300/689 (43%), Gaps = 70/689 (10%) Query: 6 KYRNIGIFAHVDAGKTTTTERILKLTGRIHKAGETHDGESTTDFMVQEAERGITIQSAAV 65 K NIG+ AHVDAGKTT TE +L +G I + G G + TD + E +RGITIQ+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 66 SCFWKDHRFNVIDTPGHVDFTVEVYRSLKVLDGGIAVFCGSGGVEPQSETNWRYANESEV 125 S W++ + N+IDTPGH+DF EVYRSL VLDG I + GV+ Q+ + + + Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 126 ARIIFVNKLDRMGADFLRVVKQTKDVLAATPLVMVLPIGIEDEFKGVVDLLTRQAYVWDE 185 I F+NK+D+ G D V + K+ L+A ++ ++ + Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIK------------------QKVEL--- 160 Query: 186 TGLPENYSIQEIPADMVDLVEEYREQLIETAVEQDDDLMEAYMEGEEPSIEDLKRCIRKG 245 P + + + +T +E +DDL+E YM G+ +L++ Sbjct: 161 --YPNMCVT-----NFTESEQ------WDTVIEGNDDLLEKYMSGKSLEALELEQEESIR 207 Query: 246 TRTMAFFPTFCGSAFKNKGMQLVLDAVVDYLPAPNEVDPQPLTDEEGNETGEYAIVSADE 305 + FP + GSA N G+ +++ + + + T +E Sbjct: 208 FHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSS--------THRGQSE----------- 248 Query: 306 SLKALAFKI-MDDRFGALTFVRIYSGRLKKGDTILNSATGKTERIGRMCEMLANDRIEIE 364 L FKI ++ L ++R+YSG L D++ S K +I M + + +I+ Sbjct: 249 -LCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKID 306 Query: 365 SAEAGDIIAIVGMKNVQTGHTLCDVKYPCTLEAMVFPEPVISIAVAPKDKGGSEKMAIAI 424 A +G+I+ + + ++ L D K E + P P++ V P E + A+ Sbjct: 307 KAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDAL 365 Query: 425 GKMIAEDPSFRVETDEDSGETILKGMGELHLDIKVDILKRTYGVELIVGEPQVAYRETIT 484 ++ DP R D + E IL +G++ +++ +L+ Y VE+ + EP V Y E Sbjct: 366 LEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYMERPL 425 Query: 485 QMVEDQYTHKKQSGGSGQFGKIEYIIRPGEPNSGFVFKSSVVGGNVPKEYWPAVEKGFAS 544 + E YT + + + I + P SG ++SSV G + + + AV +G Sbjct: 426 KKAE--YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRY 483 Query: 545 MMNTGTIAGFPVLDVEFELTDGAYHAVDSSAIAFEIAAKAAFRQSIAKAKPQLLEPIMKV 604 G + G+ V D + G Y++ S+ F + A Q + KA +LLEP + Sbjct: 484 GCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSF 542 Query: 605 DVFSPDDNVGDVIGDLNRRRGMIKDQVAGVTGVRVKADVPLSEMFGYIGTLRTMTSGRGQ 664 +++P + + D + I D V + ++P + Y L T+GR Sbjct: 543 KIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSV 602 Query: 665 FSMEFSHYSPC----------PNSVADKV 683 E Y PNS DKV Sbjct: 603 CLTELKGYHVTTGEPVCQPRRPNSRIDKV 631
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 28.9 bits (64), Expect = 0.006 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 5/72 (6%) Query: 35 QEINEIALQQQQREKARQQAVKERQLAEYQQQQIAIQQAAEQRRIAQQNEAARIRKAEAW 94 Q + +I + + +R + E A A+Q E+ R+A+ E AR ++AEA Sbjct: 92 QRLKDIVNEALRHNASRTPSATELAHANNA----AMQAEDERLRLAKAEEKAR-KEAEAA 146 Query: 95 RKYYIVPEDCKN 106 K + E + Sbjct: 147 EKAFQEAEQRRK 158
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 31.8 bits (72), Expect = 0.022 Identities = 14/71 (19%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Query: 354 SGLEPLTIDAQTLFVNVGERTN---VTGSAKFLKLIKEGKFEQALDVAREQVESGAQIID 410 +P+ + + + +TN VT + + ++ + LD+ R QV A I + Sbjct: 298 QAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLE--RVIAQLDIRRPQVLVEAIIAE 355 Query: 411 INMDEGMLDGV 421 + +G+ G+ Sbjct: 356 VQDADGLNLGI 366
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.016 Identities = 10/58 (17%), Positives = 22/58 (37%), Gaps = 4/58 (6%) Query: 14 ATSANMALQVSQLSWAIEGKTILSEISFALPKG----EMLGLIGPNGAGKSSLLRCLY 67 T + + + + ++ ++ + G + L G G GKS+L+ L Sbjct: 560 KTPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLV 617
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 39.2 bits (91), Expect = 1e-05 Identities = 46/196 (23%), Positives = 74/196 (37%), Gaps = 19/196 (9%) Query: 4 RRFI-ALGLSLALLPI---AAMAEPAKRIIALSPHAVEMLYAIGAGESIVAATDYADY-- 57 RR + A+ LS L + A A RI+AL VE+L A+G D +Y Sbjct: 10 RRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGI--VPYGVADTINYRL 67 Query: 58 ----PEAAKKIPSIGGYYGIQIERVLELNPDLIVVWDTGNKA--EDINQL-KSLGFKLYS 110 P + +G +E + E+ P + VW G E + ++ GF +S Sbjct: 68 WVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFM-VWSAGYGPSPEMLARIAPGRGFN-FS 125 Query: 111 SSPKTLEDVAKEIEELGALTGRTEQASQVAADYRNQLLQLRSENAAKSE-PKVFYQLWST 169 + L K + E+ L A A Y + + ++ + P + L Sbjct: 126 DGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDP 185 Query: 170 PLMTV-AKNSWIQQII 184 M V NS Q+I+ Sbjct: 186 RHMLVFGPNSLFQEIL 201
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 41.8 bits (98), Expect = 9e-08 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 3/55 (5%) Query: 3 LSKIKVNTGFTLIELMIAIAIVGILASIALPSYQEHVRNTRRTDARD---ALSNA 54 + GFTL+E+M+ I I+G+LAS+ +P+ + + A AL NA Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENA 55
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 38.3 bits (89), Expect = 2e-06 Identities = 17/51 (33%), Positives = 30/51 (58%) Query: 3 TKKILGFTLTELMVVVAIVAIIAGIAAPSFASMIRENTARTQVNELLALTN 53 T K GFTL E+MVV+ I+ ++A + P+ + + V++++AL N Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALEN 54
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.9 bits (67), Expect = 0.002 Identities = 13/23 (56%), Positives = 17/23 (73%), Gaps = 2/23 (8%) Query: 4 RKQKGFSLIEIMVTSFIVAFGIL 26 KQ+GF+L+EIMV IV G+L Sbjct: 5 DKQRGFTLLEIMVV--IVIIGVL 25
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 272 bits (697), Expect = 3e-97 Identities = 131/168 (77%), Positives = 150/168 (89%) Query: 2 PLLDSFTVDHTRMNAPAVRVAKHMSTPKGDAITVFDLRFCAPNKDILSERGIHTLEHLFA 61 PLLDSFTVDHTRMNAPAVRVAK M TPKGD ITVFDLRF APNKDILSE+GIHTLEHL+A Sbjct: 1 PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYA 60 Query: 62 GFMRDHLNGSDVEIIDISPMGCRTGFYMSLIGEPSERQVADAWLASMEDVLKVVEQSEIP 121 GFMR+HLNG VEIIDISPMGCRTGFYMSLIG PSE+QVADAW+A+MEDVLKV Q++IP Sbjct: 61 GFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIP 120 Query: 122 ELNEYQCGTYQMHSLEQAQDIARNIIAAGVSVNRNDDLKLSDEILGKL 169 ELNEYQCGT MHSL++A+ IA+NI+ GV+VN+ND+L L + +L +L Sbjct: 121 ELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESMLREL 168
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 29.9 bits (67), Expect = 0.031 Identities = 55/244 (22%), Positives = 87/244 (35%), Gaps = 48/244 (19%) Query: 417 EHVSINREVKQAFAGLDEADFSDSDWMPQLGVLYDAGDWRFSTDIRRAWTAASAGNT--- 473 E N + AFAGL D+ D+ GVLYD W TD+ + S Sbjct: 87 EGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLYDVEGW---TDMLPEFGGDSYTYADNY 143 Query: 474 -TQEAQVSLHYQVSAQYAREGIKADLRAYVQ-----EFDNLHVDCDSYSMCADERLLTQE 527 T A Y+ + + G+ L +Q E + + + + + Sbjct: 144 MTGRANGVATYRNTDFF---GLVDGLNFALQYQGKNESQSADDVNIGTNNRNNGDDIRYD 200 Query: 528 NIPDVLTYGVELGLGYRWDLGGVELPLGLNYQYLSAEYQTSTCTDVQ----GCVLEGDRL 583 N G G+ +D+G +G + A Y TS T+ Q G + GD+ Sbjct: 201 N-------GDGFGISTTYDIG-----MGFS---AGAAYTTSDRTNEQVNAGGTIAGGDKA 245 Query: 584 -AWLPEHQLQLSAGIKYAQYRLNLEAAYQSERDFSQFGSEQERISGQW-----RVDLAAN 637 AW +AG+KY + L Y R+ + +G + G ++ A Sbjct: 246 DAW--------TAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQ 297 Query: 638 YDFD 641 Y FD Sbjct: 298 YQFD 301
>adhesinb#Adhesin B signature. Length = 310 Score = 31.4 bits (71), Expect = 0.003 Identities = 18/95 (18%), Positives = 34/95 (35%), Gaps = 16/95 (16%) Query: 142 REARRTFEVIAEELDIVIQKNGTMAFDNAIIAY----EPLWAVGTGKSATPEQAQEVHAF 197 +EA+ F I E +++ G F AY +W + T + TP+Q + + Sbjct: 186 KEAKEKFNNIPGEKKMIVTSEG--CFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEK 243 Query: 198 IRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQ 232 +RK + L+ S ++ Sbjct: 244 LRKT----------KVPSLFVESSVDDRPMKTVSK 268
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 121 bits (305), Expect = 2e-39 Identities = 63/110 (57%), Positives = 82/110 (74%) Query: 1 MYEVLVVVYLLVALGLIGLILIQQGKGADMGASFGAGASGTLFGSSGSGNFLTRTTAILA 60 MYE L+VV+L+VA+GL+GLI++QQGKGADMGASFGAGAS TLFGSSGSGNF+TR TA+LA Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 61 IAFFTLSLLIGNLSANHAKNEDTWKNLGVDEQVTQPVDQATEKSETKIPD 110 FF +SL++GN+++N W+NL + Q A K + IP+ Sbjct: 61 TLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPAKPTSDIPN 110
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 69.1 bits (169), Expect = 4e-14 Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 18/133 (13%) Query: 392 IMGHVDHGKTSLLDYIRRAKVAAGEAG------------------GITQHIGAYHVETDN 433 ++ HVD GKT+L + + A E G GIT G + +N Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 434 GMITFLDTPGHAAFTAMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAGNVPLIVAV 493 + +DTPGH F A R D +L+++A DGV QT + +P I + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 494 NKMDKPEADIDRV 506 NK+D+ D+ V Sbjct: 128 NKIDQNGIDLSTV 140
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.1 bits (65), Expect = 0.014 Identities = 11/75 (14%), Positives = 20/75 (26%), Gaps = 3/75 (4%) Query: 69 NEQRARFHYDRGVIYDSVGLRLMARIDFMQALKLQPDLADAYNFLGIYYTQEGEYDSAYE 128 + +RF G ++G +A + + Q+GE A Sbjct: 66 DHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAES 125 Query: 129 AFDGVLEL---SPNY 140 EL + Sbjct: 126 GLFLAQELIADKTEF 140
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 198 bits (504), Expect = 3e-58 Identities = 107/461 (23%), Positives = 210/461 (45%), Gaps = 47/461 (10%) Query: 10 KRRTFAIISHPDAGKTTITEKVLLFGNALQKAGTV-KGKKSGQHAKSDWMEMEKDRGISI 68 K +++H DAGKTT+TE +L A+ + G+V KG ++D +E+ RGI+I Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGT-----TRTDNTLLERQRGITI 56 Query: 69 TTSVMQFPYGGALVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEDRTIKLMEVT 128 T + F + VN++DTPGH DF + YR+L+ +D +++I + GV+ +T L Sbjct: 57 QTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 129 RLRDTPIVTFMNKLDRDIRDPIELMDEVEDVLNIACAPITWPIGSGKEFKGVYHILRDEV 188 R P + F+NK+D++ D + ++++ L+ +++ +V Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEI------------------VIKQKV 158 Query: 189 VLYQSGMGHTIQERRVIEGIDNPELDKAIGSYAADLR-DEMELVRGASNEFDHQAFLKGE 247 LY + E + + D + Y + + +EL + S F Sbjct: 159 ELYPNMCVTNFTESEQWDTVIEGN-DDLLEKYMSGKSLEALELEQEES-----IRFHNCS 212 Query: 248 LTPVFFGTALGNFGVDHILDGIVEWAPKPLPRESDARMIMPDEEKFTGFVFKIQANMDPK 307 L PV+ G+A N G+D++++ I R + + G VFKI+ K Sbjct: 213 LFPVYHGSAKNNIGIDNLIEVITNKFYSSTHR---------GQSELCGKVFKIE--YSEK 261 Query: 308 HRDRVAFMRVCSGRYEQGMKMHHVRIGKDVNVSDALTFMAGDRERAEVAYPGDIIGLHNH 367 R R+A++R+ SG + K + +++ T + G+ + + AY G+I+ L N Sbjct: 262 -RQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKIDKAYSGEIVILQNE 319 Query: 368 GTIRIGDTFTQGEKFRFTGVPNFAPEMFR-RIRLRDPLKQKQLLKGLVQLSEEG-AVQVF 425 +++ + + + + P +++ LL L+++S+ ++ + Sbjct: 320 F-LKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYY 378 Query: 426 RPLDTNDLIVGAVGVLQFEVVVGRLKSEYNVEAIYEGISVS 466 T+++I+ +G +Q EV L+ +Y+VE + +V Sbjct: 379 VDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVI 419
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 81.6 bits (201), Expect = 3e-20 Identities = 77/240 (32%), Positives = 109/240 (45%), Gaps = 23/240 (9%) Query: 60 YLEMEFGGRSGIFDLYGYVDVFNLANESSKDGDKNPGSGTSKLFMKFAPRVSIDALTGKD 119 YLE E + FD YGY+D +S K + S LFM+ PR SID LT D Sbjct: 58 YLEYEAFAKKDWFDFYGYIDAPVFFGGNSTA--KGIWNKGSPLFMEIEPRFSIDKLTNTD 115 Query: 120 LSFGPIQEVYFSTLFNWD-GLNGEGVNSTFW-GVGADVNVPWLGKTGMNLYGYYD----- 172 LSFGP +E YF+ + +D G N ST++ G+G D++ +N+Y Y Sbjct: 116 LSFGPFKEWYFANNYIYDMGRNDSQEQSTWYMGLGTDIDTGLPMSLSLNVYAKYQWQNYG 175 Query: 173 -MNAKEWNGYQFSANWFKPFYFFDNKSFLSFQGYIDYQFGAD------EDKTAFVPKTSN 225 N EW+GY+F +F P S LS+ G+ ++ +G+D D +TSN Sbjct: 176 ASNENEWDGYRFKVKYFVPLTDLWGGS-LSYIGFTNFDWGSDLGDDNFYDLNGKHARTSN 234 Query: 226 --GGNIFFGL---YWHSDRYALGYGLKG-FKDVYLLEDGAGALALESTGWSHYLSATYKF 279 + L +WH A + G + D L G G ++ STGW Y Y F Sbjct: 235 SIASSHILALNYAHWHYSIVARYFHNGGQWADDAKLNFGDGPFSVRSTGWGGYFVVGYNF 294
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 52.4 bits (125), Expect = 4e-10 Identities = 41/189 (21%), Positives = 75/189 (39%), Gaps = 10/189 (5%) Query: 12 VLITGASSGIGLQLAKDYLAAGWHVIACGRDKAKLDALAETVLIGA---TCISFDINERS 68 ITGA+ GIG +A+ + G H+ A + KL+ + ++ A D+ + + Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 69 QVQENALRIKDLLAQCACQLDLVVLNAGGCEYIDDAKHFDDRLFERVVHTNLIAMGYCLG 128 + E RI+ + +D++V N G D +E N + Sbjct: 71 AIDEITARIEREMGP----IDILV-NVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 129 AFLPLMP--RGARLALMSSSATYLAFPRAEAYGASKAGVQYLAASLRLDLAQHGISVSVI 186 + M R + + S+ + AY +SKA L L+LA++ I +++ Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 187 CPGFVATPL 195 PG T + Sbjct: 186 SPGSTETDM 194
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 24.7 bits (53), Expect = 0.035 Identities = 8/30 (26%), Positives = 15/30 (50%) Query: 1 MAKSMKNYWMLMLVFVSLSLTACSNIDFQF 30 M K +K + + V +S L++C + F Sbjct: 1 MKKQLKYCFFSLFVSLSSILSSCGSTTFVL 30
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 32.2 bits (73), Expect = 0.001 Identities = 29/156 (18%), Positives = 57/156 (36%), Gaps = 11/156 (7%) Query: 76 PELEDVHVAMAYYYQTVGDLVRTEQAYQDAINTKDASGDSMNNFGVFLCQQKQYDKAEKM 135 + ++ +AM + + G + + + + + Q +Y+ A K+ Sbjct: 6 TDTQEYQLAMESFLKGGGTI-------AMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKV 58 Query: 136 FLAAIEMPKYTRTASSYEN-LGICSRDAGQTEKARQYFQMALKYDPRRSVSLLELAELGL 194 F A + Y S + LG C + GQ + A + D + AE L Sbjct: 59 FQALCVLDHYD---SRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLL 115 Query: 195 DKGDYVDAQNQLARYHQVAAQTPESLTLGIKIEQAL 230 KG+ +A++ L ++ A E L ++ L Sbjct: 116 QKGELAEAESGLFLAQELIADKTEFKELSTRVSSML 151
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 32.5 bits (74), Expect = 0.005 Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 35/159 (22%) Query: 199 IKLAIIGKPNVGKSTLTNRIL----GEERVVVYDEPGTTRDSIYIPMER----------- 243 I + ++ + GK+TLT +L + D+ T D+ + +R Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSF 63 Query: 244 --DGREYVIIDTAGVRRRSKVHEVIEKFSVIKTLKAVEDANVVLLIIDAREGIAEQDLGL 301 + + IIDT G + + E V ++L ++ A +L+I A++G+ Q L Sbjct: 64 QWENTKVNIIDTPG-----HMDFLAE---VYRSLSVLDGA---ILLISAKDGVQAQTRIL 112 Query: 302 LGFALNAGRALVIAVNKWD--GID-----QGIKDRVKSE 333 G + +NK D GID Q IK+++ +E Sbjct: 113 FHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAE 151
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 31.3 bits (70), Expect = 0.019 Identities = 32/138 (23%), Positives = 61/138 (44%), Gaps = 11/138 (7%) Query: 138 VLDDFAKADVLFKRTEPAPFKSVNVLAEGRRAL------EVANVEMGLALAEDEIDYLVE 191 ++ D AK V+ + K ++AEG + V + +++A E +L+E Sbjct: 102 LMSDVAKGTVVASQEATIVAKCSGMVAEGANKVVEMSKKAVQETQKAVSVA-GEATFLIE 160 Query: 192 NFVRLNRNPNDIELMMFAQ--ANSEHCRHKIFNADWTIDGEAQ-PKSLFKMIKNTFETTP 248 + LN++PN+ EL + + A E + + ++ +D Q + + M+ + Sbjct: 161 KQIMLNKSPNNKELELTKEEFAKVEQVKETLMASERALDETVQEAQKVLNMVNGLNPSNK 220 Query: 249 DHVLSAYKDNAAVMEGSV 266 D VL A KD A + V Sbjct: 221 DQVL-AKKDVAKAISNVV 237
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.5 bits (152), Expect = 4e-13 Identities = 24/128 (18%), Positives = 52/128 (40%), Gaps = 12/128 (9%) Query: 180 HIMVIDDSAVARKQIIRALESLNLQIDTAKDGREALDKLKTIAAEMNNVAEEIPLIISDI 239 I+V DD A R + +AL + + + A + L+++D+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA---------AGDGDLVVTDV 55 Query: 240 EMPEMDGYTLTAEIRDDPKLKHIKVVLHTSLSGVFNQAMVQKVGANDFIAK-FNPDELAA 298 MP+ + + L I+ + V++ ++ + + GA D++ K F+ EL Sbjct: 56 VMPDENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG 113 Query: 299 AVNKHLSL 306 + + L+ Sbjct: 114 IIGRALAE 121
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 33.0 bits (75), Expect = 3e-04 Identities = 9/38 (23%), Positives = 18/38 (47%) Query: 99 NVNVMEEMADMISASRSYQMNVQVAEAAKSMLQQTLGM 136 VN+ EE ++ + Y N QV + A ++ + + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 29.9 bits (67), Expect = 0.003 Identities = 16/67 (23%), Positives = 29/67 (43%), Gaps = 6/67 (8%) Query: 5 SIFDVAGSGMSAQSVRLNTTASNIANADSVSSSIDKTYRSRHPIFEAEMAKAQSQQQASQ 64 S+ + A SG++A LNT ++NI++ + Y + I + + Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYN------VAGYTRQTTIMAQANSTLGAGGWVGN 55 Query: 65 GVAVKGI 71 GV V G+ Sbjct: 56 GVYVSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 40.3 bits (94), Expect = 1e-05 Identities = 15/35 (42%), Positives = 22/35 (62%) Query: 2 SFNIALSGISAAQKDLNTTANNIANANTIGFKESR 36 N A+SG++AAQ LNT +NNI++ N G+ Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQT 37 Score = 37.6 bits (87), Expect = 9e-05 Identities = 12/49 (24%), Positives = 25/49 (51%) Query: 405 SISSSALEQSNIDLTTELVDLISAQRNFQANSRTLEVNNTLQQTVLQIR 453 +S+ S ++L E +L Q+ + AN++ L+ N + ++ IR Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 45.3 bits (107), Expect = 1e-07 Identities = 19/119 (15%), Positives = 41/119 (34%), Gaps = 4/119 (3%) Query: 145 DDATSITVSAEGEVSVKTPGTAENQVVGQLSMSDFINPSGLDPMGQNLYTETG---ASGT 201 D I +++E + + + Q + + +L ++ G A+ Sbjct: 427 TDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLK 486 Query: 202 PIQGTASLDGMGAIRQGALETSNVNVTEELVNLIESQRIYEMNSKVISAVDQMLAYVNQ 260 T + + S VN+ EE NL Q+ Y N++V+ + + + Sbjct: 487 TSSATQGNV-VTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 35.7 bits (82), Expect = 2e-04 Identities = 9/36 (25%), Positives = 20/36 (55%) Query: 5 LWISKTGLDAQQTDIAVISNNVANASTVGYKKSRAV 40 + + +GL+A Q + SNN+++ + GY + + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI 39
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 145 bits (368), Expect = 1e-45 Identities = 76/220 (34%), Positives = 108/220 (49%), Gaps = 19/220 (8%) Query: 11 LLLTACSSTSKKPIADDPFYAPVYPEAPPTKIAATGSIYQDSQAA-----SLYSDIRAHK 65 L LT C+ P+ A P P A GSI+Q +Q L+ D R Sbjct: 17 LSLTGCAWIPSTPLVQGATSAQPVPGPTP---VANGSIFQSAQPINYGYQPLFEDRRPRN 73 Query: 66 VGDIITIVLKEATQAKKSAGNQIKKGSDLSLDPIYAGGSNVS------IGGVPLDLRYKD 119 +GD +TIVL+E A KS+ + + G V G D+ Sbjct: 74 IGDTLTIVLQENVSASKSSSANASRDGKTNF-----GFDTVPRYLQGLFGNARADVEASG 128 Query: 120 SMNTKRESDADQSNSLDGSISANVMQVLNNGNLVVRGEKWISINNGDEFIRVTGIVRSQD 179 + A+ SN+ G+++ V QVL NGNL V GEK I+IN G EFIR +G+V + Sbjct: 129 GNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRT 188 Query: 180 IKPDNTIDSTRMANARIQYSGTGTFADAQKVGWLSQFFMS 219 I NT+ ST++A+ARI+Y G G +AQ +GWL +FF++ Sbjct: 189 ISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLN 228
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 378 bits (973), Expect = e-133 Identities = 161/367 (43%), Positives = 223/367 (60%), Gaps = 14/367 (3%) Query: 5 LILAVAMLAFSLPSQAE--RIKDIANVQGVRSNQLIGYGLVVGLPGTGEKTR---YTEQT 59 L+ + + P+QA+ RIKDIA++Q R NQLIGYGLVVGL GTG+ R +TEQ+ Sbjct: 11 LVFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQS 70 Query: 60 FTTMLKNFGINLPDNFRPKIKNVAVVAVHADMPAFIKPGQELDVTVSSLGEAKSLRGGTL 119 ML+N GI + KN+A V V A++P F PG +DVTVSSLG+A SLRGG L Sbjct: 71 MRAMLQNLGITTQGG-QSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNL 129 Query: 120 LQTFLKGVDGNVYAIAQGSLVVSGFSADGLDGSKVIQNTPTVGRIPNGAIVERSVATPFS 179 + T L G DG +YA+AQG+L+V+GFSA G D + + Q T R+PNGAI+ER + + F Sbjct: 130 IMTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFK 188 Query: 180 TGDYLTFNLRRSDFSTAQRMADAINDL----LGPDMARPLDATSVQVSAPRDVSQRVSFL 235 L LR DFSTA R+AD +N G +A P D+ + V PR V+ + Sbjct: 189 DSVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPR-VADLTRLM 247 Query: 236 ATLENIEVEPADESAKVIVNSRTGTIVVGQNVKLLPAAVTHGGLTVTIAEATQVSQPNAL 295 A +EN+ VE D AKV++N RTGTIV+G +V++ AV++G LTV + E+ QV QP Sbjct: 248 AEIENLTVET-DTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPF 306 Query: 296 ANGQTTVTSNSTINASESNRRMFMFNPGTTLDELVRAVNLVGAAPSDVLAILEALKVAGA 355 + GQT V + I A + ++ + G L LV +N +G ++AIL+ +K AGA Sbjct: 307 SRGQTAVQPQTDIMAMQEGSKVAIVE-GPDLRTLVAGLNSIGLKADGIIAILQGIKSAGA 365 Query: 356 LHGELII 362 L EL++ Sbjct: 366 LQAELVL 372
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 180 bits (457), Expect = 6e-56 Identities = 108/362 (29%), Positives = 158/362 (43%), Gaps = 79/362 (21%) Query: 12 DLGGLDSLRAQAQKDEKGALKKVAQQFEGVFVQMLMKSMRDANAVFESDSPLNSQYTKFY 71 D L+ L+A+A +D ++ VA+Q EG+FVQM++KSMRDA D +S++T+ Y Sbjct: 14 DAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALP---KDGLFSSEHTRLY 70 Query: 72 EQMRDQQLSVDLSDKGVLGLADMMVQQLSPESSQFTPASVLRNDGGMKLQHDAKAFNIPA 131 M QQ++ Q T G+ L P Sbjct: 71 TS--------------------MYDQQIA---QQMTAG------KGLGLAEMMVKQMTPE 101 Query: 132 QATSAAETQTAAAPVVAAQGVPASIARPSANVDNGDGVTSSLDIDRPERLLAIDTPKPAW 191 Q E T AAP+ + ++ + Sbjct: 102 Q--PLPEESTPAAPM--------KFPLETVVRYQNQALSQLV------------------ 133 Query: 192 SEQPLSPIEPVISGQILPTAAFRETQKTLKFGSREEFLATLYPHAEKAAKALGTQPEVLL 251 Q P S G + FLA L A+ A++ G ++L Sbjct: 134 --QKAVPRNYDDSLP----------------GDSKAFLAQLSLPAQLASQQSGVPHHLIL 175 Query: 252 AQSALETGWGQKIVRGNNGAPSHNLFNIKADRRWQGDKANVSTLEFEQGIAVRQKADFRV 311 AQ+ALE+GWGQ+ +R NG PS+NLF +KA W+G ++T E+E G A + KA FRV Sbjct: 176 AQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRV 235 Query: 312 YADFEHSFNDFVSFIAEGERYQAAKKVAASPTQFIRALQDAGYATDPKYAEKVIKVMQSI 371 Y+ + + +D+V + RY AA AAS Q +ALQDAGYATDP YA K+ ++Q + Sbjct: 236 YSSYLEALSDYVGLLTRNPRY-AAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQM 294 Query: 372 SE 373 Sbjct: 295 KS 296
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 212 bits (542), Expect = 2e-63 Identities = 129/486 (26%), Positives = 205/486 (42%), Gaps = 20/486 (4%) Query: 4 DLLNIARTGVLASQSQLGVTSNNIANANTAGYHRQVATQTTLDSQRLGNSFYGTGTYVSD 63 L+N A +G+ A+Q+ L SNNI++ N AGY RQ +S + G G YVS Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Query: 64 VKRIYNDYAARELRIGQTTLSAAEASYGKLSELDQVFSQIGKIVPQSLNDLFSGLNSLAD 123 V+R Y+ + +LR QT S A Y ++S++D + S + + D F+ L +L Sbjct: 62 VQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVS 121 Query: 124 LPADLGIRSSTLNDAKQLANSLNQMQSTLNGQLTQTNDQITGMTKRINEISTELANLNLE 183 D R + + ++ L N L Q Q N I +IN + ++A+LN + Sbjct: 122 NAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQ 181 Query: 184 LMKSPNQDAM-----LLDKQDALVQELSQYAQVNVIPLENGAKSIMLGGAIMLVSGEV-- 236 + + A LLD++D LV EL+Q V V + G +I + LV G Sbjct: 182 ISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTAR 241 Query: 237 PMSISTATGDPFPNELQLMSTIGSQSVRVDPTKLGGQLGALFEYREQTLVPAGLELDQLA 296 ++ ++ DP + + + G LG + +R Q L L QLA Sbjct: 242 QLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLA 301 Query: 297 LGVADNFNKLQAEGFDLNGQVGADIFKDINDPLMSIGRVAGFSGNTGNATLGVNIDDTSA 356 L A+ FN GFD NG G D F + V + N G+ +G + D SA Sbjct: 302 LAFAEAFNTQHKAGFDANGDAGEDFFA------IGKPAVLQNTKNKGDVAIGATVTDASA 355 Query: 357 LSGGSYELSF--TAPATYELRDTQTGTITPLTLNGTKLEGGAGFSIDIKAGAMASGDRFA 414 + Y++SF L T T+TP +G G A D F Sbjct: 356 VLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFT----GTPAVNDSFT 411 Query: 415 IRPTAGAANGIEVVMTDPKGIAAAAPKITPDAANSGNTQVKVTQITNRSAANFPTTGSEL 474 ++P + A ++V++TD IA A+ + D+ N N Q + +N + ++ Sbjct: 412 LKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDN-RNGQALLDLQSNSKTVGGAKSFNDA 470 Query: 475 TIQLNT 480 L + Sbjct: 471 YASLVS 476 Score = 81.5 bits (201), Expect = 2e-18 Identities = 37/102 (36%), Positives = 52/102 (50%) Query: 536 EGDNTNALAMAKLSETKVMNGGKSTLADVFEQTKQDIGSQTKAAEVRVGAADAIYQQAYA 595 + DN N A+ L GG + D + DIG++T + + Q Sbjct: 442 DSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLSN 501 Query: 596 RVESESGVNLDEEAANLMRFQQAYQASARIMSTAQQIFDTLL 637 + +S SGVNLDEE NL RFQQ Y A+A+++ TA IFD L+ Sbjct: 502 QQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALI 543
>FLAGELLIN#Flagellin signature. Length = 507 Score = 50.4 bits (120), Expect = 7e-09 Identities = 33/233 (14%), Positives = 83/233 (35%), Gaps = 4/233 (1%) Query: 20 QTATSKILDQLSSGKKVNTSGDDPVAALGIDNLNQRNALVDQFMKNIDYATNHLQQTESQ 79 Q++ S +++LSSG ++N++ DD + + Q +N + + Q TE Sbjct: 21 QSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNANDGISIAQTTEGA 80 Query: 80 LGQADTLISSMKDLMLQGSNGSQTSEERQTIADDLRKSLDQLLTIANTKDESGNYLFAGN 139 L + + + +++L +Q +NG+ + + ++I D++++ L+++ ++N +G + + + Sbjct: 81 LNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSNQTQFNGVKVLSQD 140 Query: 140 KTDTLPFQFDANGKIVYQGDSGVHSAIIASGIQLNTNVAGDTAFIKSPNAMGDYSVNYLP 199 + + I ++ G NV G +V Sbjct: 141 NQMKIQVGANDGETITIDLQKIDVKSLGLDG----FNVNGPKEATVGDLKSSFKNVTGYD 196 Query: 200 SQQGEFSVTSAKLDGVTPSLSDYKINFLDDGAGGINVEVTDTATPANVISAAA 252 + + ++ D T N + Sbjct: 197 TYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAENNTAVDL 249
>FLAGELLIN#Flagellin signature. Length = 507 Score = 206 bits (524), Expect = 1e-62 Identities = 156/507 (30%), Positives = 231/507 (45%), Gaps = 25/507 (4%) Query: 2 AISVNTNVTSMKAQNQLNGANNRLSTSMERLSSGLRINSAKDDAAGLQISNRMTSQINGI 61 A +NTN S+ QN LN + + LS+++ERLSSGLRINSAKDDAAG I+NR TS I G+ Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 GVAMRNANDGISIAQTAEGAMQESTNILQRMRDLSLQSANGSNSSEDRAAMQKELNALQS 121 A RNANDGISIAQT EGA+ E N LQR+R+LS+Q+ NG+NS D ++Q E+ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 ELTRIADTTSFGGQKLLDGSYGTQSFQVGAQANETISVSLKSVAAADIGAYKSDAAGSKF 181 E+ R+++ T F G K+L QVGA ETI++ L+ + +G + G K Sbjct: 121 EIDRVSNQTQFNGVKVLSQD-NQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 GGDLVTAVAGSNGSAGGNLSITQGTKTTTFATAANDTAAEVAGKINKAGTGVTATAQTTI 241 + N + ++ + A T +K TT Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 242 EANLTEAFDKGLTMKVDDGNSTSSLDLTGIGN-NDDLAKAINNVSGETGVSAKLENGVLT 300 +A A D T K G + + I + V+ + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKV 299 Query: 301 ITSSKGADISFSD-----------------------TATAGTGTLTLKNISADGTSSAVS 337 T+ G ++ + + G T K + S + Sbjct: 300 STTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLE 359 Query: 338 TIDGTDTTVDNATAVGSVSLTASSAYSISGGIAAELTTEVAGVFAGVNSVDISSAAGSQS 397 + + A+ G + +GV +N ++ + + Sbjct: 360 ANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTAN 419 Query: 398 ALAIIDGAIASIDSSRSDLGAVQNRMSFTINNLSNIQSNVTDARSRIQDVDFASETAQLT 457 LA ID A++ +D+ RS LGA+QNR I NL N +N+ ARSRI+D D+A+E + ++ Sbjct: 420 PLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMS 479 Query: 458 KQQILSQTSSAMLAQANQLPQTALSLL 484 K QIL Q +++LAQANQ+PQ LSLL Sbjct: 480 KAQILQQAGTSVLAQANQVPQNVLSLL 506
>FLAGELLIN#Flagellin signature. Length = 507 Score = 207 bits (528), Expect = 3e-63 Identities = 156/507 (30%), Positives = 230/507 (45%), Gaps = 25/507 (4%) Query: 2 AISVNTNVTSMRAQNQLNGANSKLSTSMERLSSGLRINSAKDDAAGLQISNRMTSQVNGI 61 A +NTN S+ QN LN + S LS+++ERLSSGLRINSAKDDAAG I+NR TS + G+ Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 GVAMRNANDGISIAQTAEGAMQESTNILQRMRDLSLQSANGSNSSEDRAAMQKEVNALQS 121 A RNANDGISIAQT EGA+ E N LQR+R+LS+Q+ NG+NS D ++Q E+ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 ELTRISETTSFGGQKLLDGSYGTQSFQVGAQANETISVSLKSVAAADIGAYKSDAAGSKF 181 E+ R+S T F G K+L QVGA ETI++ L+ + +G + G K Sbjct: 121 EIDRVSNQTQFNGVKVLSQD-NQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 GGDLVTAVAGSNGSAGGNLSITQGTKTTTFATAANDTAAEVAGKINKAGTGVTATAQTTI 241 + N + ++ + A T +K TT Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 242 EANLTEAFDKGLTMKVDDGNSTSSLDLTGIGN-NDDLAKAINNVSGETGVSAKLENGVLT 300 +A A D T K G + + I + V+ + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKV 299 Query: 301 ITSSKGADISFSD-----------------------TATAGTGTLTLKNISADGTSSAVS 337 T+ G ++ + + G T K + S + Sbjct: 300 STTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLE 359 Query: 338 TIDGTDTTVDNATAVGSVSLTASSAYSISGGIAAELTTEVAGVFAGVNSVDLSTASGSQS 397 + + A+ G + +GV +N + + + Sbjct: 360 ANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTAN 419 Query: 398 ALAIIDGAIAGIDSQRADLGAVQNRMNFTINNLSNIQSNVTDARSRIQDVDFASETAQLT 457 LA ID A++ +D+ R+ LGA+QNR + I NL N +N+ ARSRI+D D+A+E + ++ Sbjct: 420 PLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMS 479 Query: 458 KQQILSQTSSAMLAQANQLPQTALSLL 484 K QIL Q +++LAQANQ+PQ LSLL Sbjct: 480 KAQILQQAGTSVLAQANQVPQNVLSLL 506
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 55.2 bits (133), Expect = 2e-12 Identities = 18/87 (20%), Positives = 32/87 (36%), Gaps = 3/87 (3%) Query: 8 TQQAVALGYD-GKH-APKVVASGEGLVADEIIALAKASGVYIHQDPHLSNFL-RLLELGE 64 T A+ + Y G+ P V + +A+ GV I Q L+ L + Sbjct: 265 THIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEEGVPILQRIPLARALYWDALVDH 324 Query: 65 EIPKELYLLIAELIAFVYMLDGKFPEQ 91 IP E AE++ ++ + + Sbjct: 325 YIPAEQIEATAEVLRWLERQNIEKQHS 351
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 230 bits (588), Expect = 5e-78 Identities = 91/257 (35%), Positives = 134/257 (52%), Gaps = 16/257 (6%) Query: 9 LLGFALLPKVYGAEATVPDTTPKETASAVKITYDDPRDPLEGFNRAMWDFNYLYLDRYIY 68 L AL + A+ + DPLEGFNR M++FN+ LD YI Sbjct: 5 LSALALGTTLLVGCASSGTDQQGRS------------DPLEGFNRTMYNFNFNVLDPYIV 52 Query: 69 RPIAHGYNDYLPLPAKTGINNFVQNLEEPSSLVNNALQGKWGWAANAGGRFTVNTTIGLL 128 RP+A + DY+P PA+ G++NF NLEEP+ +VN LQG RF +NT +G+ Sbjct: 53 RPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMG 112 Query: 129 GVFDVADMMGMPRKQDE---FNEVLGYYGVPNGPYFMAPFAGPYVVRELASDWVDGLYFP 185 G DVA M ++ E F LG+YGV GPY PF G + +R+ D D LY Sbjct: 113 GFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPV 172 Query: 186 LSELTVWQSIVKWGLKSLHARASAIDQERLVDNALDPYTFVKDAYLQHMDYKVYDGNV-P 244 LS LT S+ KW L+ + RA +D + L+ + DPY V++AY Q D+ G + P Sbjct: 173 LSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKP 232 Query: 245 QKQEDDELLDQYMQELE 261 Q+ + + + +++++ Sbjct: 233 QENPNAQAIQDDLKDID 249
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.9 bits (236), Expect = 2e-23 Identities = 29/101 (28%), Positives = 47/101 (46%) Query: 7 SILLVEDDPVFRQIVATFLSGRGAEVVQACDGEQGLSIFKQQRFDIILADLSMPKLGGLD 66 +IL+ +DD R ++ LS G +V + D+++ D+ MP D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 67 MLKEMSKLEPLVPSIVISGNNVMADVVEALRVGACDYLVKP 107 +L + K P +P +V+S N ++A GA DYL KP Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 179 bits (456), Expect = 8e-56 Identities = 85/361 (23%), Positives = 149/361 (41%), Gaps = 51/361 (14%) Query: 1 MKILVTGGAGFIGSAVVRHIISNTQDSVINLDKLT--YAGNL-ESLVSVEASERYAFEQV 57 MK LVTG AGFIG V + ++ V+ +D L Y +L ++ + + A + F ++ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DICDRAELDRVFSQYKPDAVMHLAAESHVDRSITGPADFIQTNIVGTYTLLEAARHYWMQ 117 D+ DR + +F+ + V V S+ P + +N+ G +LE RH +Q Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 118 LDAERKVAFRFHHISTDEVYGDLPHPDEQEGQVVNQELPLFTETTPYAPSSPYSASKASS 177 + S+ VYG N+++P T+ + P S Y+A+K ++ Sbjct: 120 ---------HLLYASSSSVYGL------------NRKMPFSTDDSVDHPVSLYAATKKAN 158 Query: 178 DHLVRAWLRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKQLPIYGKGDQIRDWL 237 + + + YGLP YGP+ P+ + LEGK + +Y G RD+ Sbjct: 159 ELMAHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFT 218 Query: 238 YVEDHARALYKVV------------------TEGQIGETYNIGGHNEKQNLEVVQTICTI 279 Y++D A A+ ++ YNIG +E++ I + Sbjct: 219 YIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNS---SPVELMDYIQAL 275 Query: 280 LDALVPKASSYAEQITYVTDRPGHDRRYAIDASKISNELNWQPQETFETGLCKTVEWYLA 339 DAL +A + + +PG + D + + + P+ T + G+ V WY Sbjct: 276 EDALGIEA-----KKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330 Query: 340 N 340 Sbjct: 331 F 331
>PF06291#Lambda prophage Bor protein Length = 102 Score = 30.4 bits (68), Expect = 0.001 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 3/46 (6%) Query: 13 QTVKMNMKLSQISLALLALMITACSEPAKTVANEPVAAPHQDTQTN 58 Q KM L +LA+L IT C++ TV N+P A ++T T+ Sbjct: 2 QDNKMKKMLFSAALAML---ITGCAQQTFTVGNKPTAVTPKETITH 44
>PF06580#Sensor histidine kinase Length = 349 Score = 47.6 bits (113), Expect = 5e-08 Identities = 35/198 (17%), Positives = 74/198 (37%), Gaps = 38/198 (19%) Query: 266 NTMQDGLGLIERNLSRAAELV--------HNFKRTAADQSVLERERFNLKTYIFQIFSSL 317 N + + LI + ++A E++ ++ + + A Q L E + +Y+ + S Sbjct: 177 NALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQ-LAS-- 233 Query: 318 RPLMR-KKNIALNVELDDDIFIESYPGAIAQIFTNLVANSFRHGFPESFTGDKIITIRVQ 376 ++ + + +++ I P + Q LV N +HG + G I ++ Sbjct: 234 ---IQFEDRLQFENQINPAIMDVQVPPMLVQT---LVENGIKHGIAQLPQG-GKILLKGT 286 Query: 377 KQDSNICMQYQDNGVGMTDEVKLKAFEPFFTTARKDGGTGLGMSIIYNLVTQKLHG---T 433 K + + ++ ++ G K TG G+ + + Q L+G Sbjct: 287 KDNGTVTLEVENTGSLALKNTK--------------ESTGTGLQNVRERL-QMLYGTEAQ 331 Query: 434 IMLTSSPYQGVKVEIQIP 451 I L+ V + IP Sbjct: 332 IKLSEKQ-GKVNAMVLIP 348
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 50.4 bits (120), Expect = 2e-08 Identities = 32/194 (16%), Positives = 67/194 (34%), Gaps = 13/194 (6%) Query: 473 NQQGQDQNDQQQGDQQSSQNDQAQDQSQEQQSQQQNNSDQADKKPSQEQSTSSEQNDPEQ 532 NQ N + Q+ + + + + A PS+ T +E + E Sbjct: 989 NQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQES 1048 Query: 533 GAQDKQQASDENAKQDQQDAQQEQQQAEQQANQQNGADNNAEDKEDPASNEAKMQAKVE- 591 +K + ++ +E + + Q N + + ++ + E K A VE Sbjct: 1049 KTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEK 1108 Query: 592 DDKSKAKQEQQQAVAQKADKEK-----------QAQADKKPDTAVESVEA-PPSNSEPLP 639 ++K+K + E+ Q V + + QA+ ++ D V E +N+ Sbjct: 1109 EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT 1168 Query: 640 AEMQRALRGVSEDP 653 + + E P Sbjct: 1169 EQPAKETSSNVEQP 1182 Score = 44.7 bits (105), Expect = 1e-06 Identities = 32/225 (14%), Positives = 78/225 (34%), Gaps = 15/225 (6%) Query: 423 KAKERYQAALDKQPEFPQAKANLELAEKLLNQQQSQQNADNQDKQSQGDQNQQGQDQNDQ 482 A+ P P +AE + ++ + + ++ + ++ Sbjct: 1017 IARVDEAPVPPPAPATPSETTET-VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSN 1075 Query: 483 QQGDQQSSQNDQAQDQSQEQQSQQQNNSDQADKKPSQEQSTSSEQNDPEQGAQDKQQASD 542 + + Q+++ Q+ +++E Q+ + + +K+ + T Q P+ +Q + Sbjct: 1076 VKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQ 1135 Query: 543 ENAKQDQQDAQQE--------QQQAEQ--QANQQNGADNNAEDKEDPASNEAKMQAKVED 592 Q Q + +E + Q++ A+ + A + + E P + V Sbjct: 1136 SETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTE----STTVNT 1191 Query: 593 DKSKAKQEQQQAVAQKADKEKQAQADKKPDTAVESVEAPPSNSEP 637 S + + A ++K + SV + P N EP Sbjct: 1192 GNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEP 1236 Score = 42.4 bits (99), Expect = 6e-06 Identities = 26/200 (13%), Positives = 64/200 (32%), Gaps = 7/200 (3%) Query: 480 NDQQQGDQQSSQNDQAQDQSQEQQSQQQNNSDQADKKPSQEQSTSSEQNDPEQGAQDKQQ 539 N + + Q+ + Q S+ + E + + Sbjct: 982 NPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPS---ETTE 1038 Query: 540 ASDENAKQDQQDAQQEQQQAEQQANQQNGADNNAEDKEDPASNEAKMQAKVEDDKSKAKQ 599 EN+KQ+ + ++ +Q A + Q A+ A+ + A+ + + + Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAK-SNVKANTQTNEVAQSGSETKETQT 1097 Query: 600 EQQQAVAQKADKEKQ-AQADKKPDTAVESVEAPPSNSEPLPAEMQRALRGVSEDPQVLLR 658 + + A +EK + +K + + + P + +A DP V ++ Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQS-ETVQPQAEPARENDPTVNIK 1156 Query: 659 NKMQLEYQKRRQNGQISRDN 678 Q + Q +++ Sbjct: 1157 EP-QSQTNTTADTEQPAKET 1175
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.7 bits (77), Expect = 8e-04 Identities = 35/139 (25%), Positives = 53/139 (38%), Gaps = 19/139 (13%) Query: 28 LIALIANG--HLLVEGPPGLAKT---RAVKALCDGVEGDFHRIQ---FTPDLLPADLTG- 78 ++A + L++ G G K RA+ G F I DL+ ++L G Sbjct: 152 VLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH 211 Query: 79 -----TDIYRSQTGTFEFEAGPIFHNLILADEINRAPAKVQSALLEAMAEGQVT-VGKNS 132 T TG FE G + DEI P Q+ LL + +G+ T VG + Sbjct: 212 EKGAFTGAQTRSTGRFEQAEG----GTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRT 267 Query: 133 YKLPPLFLVMATQNPLENE 151 + +V AT L+ Sbjct: 268 PIRSDVRIVAATNKDLKQS 286
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 30.9 bits (69), Expect = 0.008 Identities = 44/219 (20%), Positives = 93/219 (42%), Gaps = 16/219 (7%) Query: 239 FLDSVAVAMAQMTSAIEEVSVNASNTSLQTKDNASQMSASQGRISHTVDSIGQLSTKIGA 298 F DS + + S + E S N L KD +Q + +++ V S + G Sbjct: 23 FADSNNANILKPQSNVLEHSDQKDNKKLDQKDQVNQALDTINKVTEDVSSKLE-----GV 77 Query: 299 AFSSVEQLSKDAAGI----DAVVTTINSISEQTNLLALNAAIEAARAGEQGRGFAVVADE 354 SS+E + + AG+ ++ ++ +++ T + + A I A +G G V + Sbjct: 78 RESSLELVESNDAGVVKKFVGSMSLMSDVAKGTVVASQEATIVAKCSGMVAEGANKVVEM 137 Query: 355 VRTLAGRTQ-------QATVEIQAMIEGLQSGTRQLSNITTEIVDRADEGRSAIIAVGDD 407 + TQ +AT I+ I +S + +T E + ++ + ++A Sbjct: 138 SKKAVQETQKAVSVAGEATFLIEKQIMLNKSPNNKELELTKEEFAKVEQVKETLMASERA 197 Query: 408 VEGMAQSVNAVFDMSSQIAASAEEQSVAARDIAGQLNEI 446 ++ Q V +M + + S ++Q +A +D+A ++ + Sbjct: 198 LDETVQEAQKVLNMVNGLNPSNKDQVLAKKDVAKAISNV 236
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 1e-04 Identities = 21/102 (20%), Positives = 34/102 (33%), Gaps = 23/102 (22%) Query: 356 LMENAFRLCISQ------VEVSARFNDQGDFELIVEDDGPGVEENLRQKIIQRGVRADTQ 409 L+EN + I+Q + + D G L VE+ G +N ++ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTK-DNGTVTLEVENTGSLALKNTKE------------ 309 Query: 410 SPGQGIGLA-VCDEIVSSYGGYLSIE-ESHLEGARFRITIPA 449 G GL V + + YG I+ + IP Sbjct: 310 --STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 78.7 bits (194), Expect = 4e-19 Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 1/124 (0%) Query: 1 MSIMRILVVEDDLILSHHLKVQLSDLGNQVQVALTAKEGFFQATNYPIDVAIVDLGLPDQ 60 M+ ILV +DD + L LS G V++ A + D+ + D+ +PD+ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGISLIQQLREEGVKAPILILTARVNWQDKVEGLNAGADDYLVKPFQKEELVARLD-ALV 119 + L+ ++++ P+L+++A+ + ++ GA DYL KPF EL+ + AL Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RRSA 123 Sbjct: 121 EPKR 124
>INTIMIN#Intimin signature. Length = 939 Score = 42.4 bits (99), Expect = 1e-05 Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 16/184 (8%) Query: 54 ATPAEVQATVVDSKTGPKAGIVVTFKLDNDELGTFTPSTGTQLTDSSGVAKIKLDTGSLA 113 ATV + +A + V+F + + GT S + T+ SG A + L + Sbjct: 575 TEAITYTATVKKNGV-AQANVPVSFNIVS---GTAVLSANSANTNGSGKATVTLKSDKP- 629 Query: 114 GAGSVTASIGTGESASMGFYSKGDGAINPGTGNKLKLSLVNAQEQAITSISSATPGIVKA 173 G V+A SA + I ++ K S+ + T++++ I Sbjct: 630 GQVVVSAKTAEMTSA-----LNANAVIFV---DQTKASITEIKADKTTAVANGQDAITYT 681 Query: 174 LYTNSSDEPLVGKVITFTSTLGKFQPESGTALTDAQGLAKIAITAGTVAGAGKIIAKVDD 233 + D+P+ + +TFT+TLGK + T TD G AK+ +T+ T G + A+V D Sbjct: 682 VKVMKGDKPVSNQEVTFTTTLGK--LSNSTEKTDTNGYAKVTLTSTTP-GKSLVSARVSD 738 Query: 234 TESE 237 + Sbjct: 739 VAVD 742 Score = 37.0 bits (85), Expect = 5e-04 Identities = 60/305 (19%), Positives = 99/305 (32%), Gaps = 48/305 (15%) Query: 379 TGMPTTNISATQPGKVTV---ALVDKDSTPLVGKVVSFSSTLGNFLPTQGTALTDALGRA 435 T SA G + A V K+ VSF+ G + + +A T+ G+A Sbjct: 561 TDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKA 620 Query: 436 SITLTAGSIEGAGEITATYG-----TAKAIIGFVTAGDEIDPVEASPEISFDIYDCNGVA 490 ++TL + T A A+I I ++A NG Sbjct: 621 TVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADK----TTAVANGQD 676 Query: 491 AWDKALKNFEVCKTTDNITNDKPGIIGAKVTRSGSTQALQQVLISAATTIGAISPSSGTA 550 A +K + DKP + +VT + TT+G +S S+ Sbjct: 677 AITYTVKVMK---------GDKP-VSNQEVTFT--------------TTLGKLSNSTEK- 711 Query: 551 ITNAEGKAILDLYANGNVGAGEISLKVKDVTATKAFEIGRVNISLKLETSLGGNLLPAGG 610 T+ G A + L + G +S +V DV A ++ + ++ + G Sbjct: 712 -TDTNGYAKVTLTST-TPGKSLVSARVSDV----AVDVKAPEVEFFTTLTIDDGNIEIVG 765 Query: 611 STI---LDVTVLNPDGS--LATGQPFTLVFTSECQASNKAIIDSPVITNGGKGYATYRST 665 + + L L A+G + S A S +T KG T Sbjct: 766 TGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVI 825 Query: 666 GCETQ 670 + Q Sbjct: 826 SSDNQ 830
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 2e-18 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 6/112 (5%) Query: 7 KIIIADDHPLFRNALRQALSSAFEHAQWYEADSADALQSVLDS-QNVSYDLVLLDLQMPG 65 I++ADD R L QALS A Y+ ++ DLV+ D+ MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAG-----YDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 66 SHGYSTLIHLRSHYPELPVVVISAHEDINTISRAIHYGGSGFIPKSASMETL 117 + + L ++ P+LPV+V+SA T +A G ++PK + L Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 28.7 bits (64), Expect = 0.010 Identities = 21/97 (21%), Positives = 41/97 (42%), Gaps = 21/97 (21%) Query: 15 AIEQRINQSEARVIKAVFPSITNHHNTLFGGEALAWMDETAFIAATRFCRKTLVTVSSDR 74 +E + A+V+ P++ N +A+ ET + V V+ Sbjct: 350 LLEN---EGSAQVVSR--PTLLTQENA----QAVIDHSETYY-----------VKVTGKE 389 Query: 75 IDFKKPIPAGTLAELIARVIHVGNTSLKVEVNIFVED 111 + K I GT+ + RV+ G+ S ++ +N+ +ED Sbjct: 390 VAELKGITYGTMLRMTPRVLTQGDKS-EISLNLHIED 425
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 301 bits (772), Expect = 7e-95 Identities = 110/418 (26%), Positives = 188/418 (44%), Gaps = 65/418 (15%) Query: 384 QPGDVLVTDMTDPDWEPIMK-RASAIVTNRGGRTCHAAIIARELGVPAVVGCGDVTDRIK 442 + ++ D+T D + K T+ GGRT H+AI++R L +PAVVG +VT++I+ Sbjct: 155 EETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQ 214 Query: 443 NGQLVTVSCAEG---------DTGYIYEGKQEFEVVSNRVDALPELP--------MKIMM 485 +G +V V EG + E + FE L P +++ Sbjct: 215 HGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAA 274 Query: 486 NVGNPDRAFDFARLPNEGVGLARLEFIINRMIGIHPKALLEFNQQDAALQEEINEMIAGY 545 N+G P EG+GL R EF+ + +D EE E Y Sbjct: 275 NIGTPKDVDGVLANGGEGIGLYRTEFL--------------YMDRDQLPTEE--EQFEAY 318 Query: 546 DSPVEFYIARLVEGIASIGSAFYPKKVIVRMSDFKSNEYANLVGGDRYEPEEENPMLGFR 605 V+ K V++R D ++ + + P+E NP LGFR Sbjct: 319 KEVVQ---------------RMDGKPVVIRTLDIGGDKELSYL----QLPKELNPFLGFR 359 Query: 606 GASRYISESFRDCFALECEAIKRVRNEMGLKNVEVMIPFVRTVKEAEQVIGLLKEQGLER 665 + + +D F + A+ R N++VM P + T++E Q +++E+ + Sbjct: 360 AIRLCLEK--QDIFRTQLRALLRAS---TYGNLKVMFPMIATLEELRQAKAIMQEEKDKL 414 Query: 666 GKDG------LRVIMMCEVPSNALLADQFLEHFDGFSIGSNDLTQLSLGLDRDSGIISHL 719 +G + V +M E+PS A+ A+ F + D FSIG+NDL Q ++ DR + +S+L Sbjct: 415 LSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYL 474 Query: 720 FDERNEAVKILLSMAIKAAKAKGAYIGICGQGPSDHADFAAWLVEQGIDTVSLNPDTV 777 + + A+ L+ M IKAA ++G ++G+CG+ D L+ G+D S++ ++ Sbjct: 475 YQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGDE-VAIPLLLGLGLDEFSMSATSI 531
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 666 bits (1721), Expect = 0.0 Identities = 262/1094 (23%), Positives = 474/1094 (43%), Gaps = 100/1094 (9%) Query: 7 SVKRPVTVWMFMLAIMLFGMVGFSRLAVKLLPDLSYPTLTIRTMYDGAAPVEVEQLVSKP 66 ++RP+ W+ + +M+ G + +L V P ++ P +++ Y GA V+ V++ Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 67 IEEAVGVVKGLRKISSISRS-GMSDVVLEFEWGTTMDMASLDVREKLDTI--ALPLDVKK 123 IE+ + + L +SS S S G + L F+ GT D+A + V+ KL LP +V++ Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 124 PLLLRFNPNLDPIMRLALSVPNASEAELKQMRTYAEEELKRRLEALSGVAAVRLSGGLEQ 183 + + +M N + Y +K L L+GV V+L G + Sbjct: 125 QGISVEKSSSSYLMVAGFVSDNPGT-TQDDISDYVASNVKDTLSRLNGVGDVQLFGA-QY 182 Query: 184 EVHIQLNQEKLSQLNLNADDIKRRINEENINLSAGKVIQGD------REYLVRTLNQFNS 237 + I L+ + L++ L D+ ++ +N ++AG++ + +F + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 238 LEELGQVIVYRDAQ-TLVRLFEVATITDAFKERSDITRIGSQESIELAIYKEGDANTVAV 296 EE G+V + ++ ++VRL +VA + + + I RI + + L I AN + Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 297 AKKLRDELVKINQD-PKQNKLEVIYDQSEFIESAVSEVTSSALMGSILSMLVIYLFLRNI 355 AK ++ +L ++ P+ K+ YD + F++ ++ EV + +L LV+YLFL+N+ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 356 IPTLIISISIPFSVIATFNMMYFADISLNIMSLGGIALAIGLLVDNAIVVLENIDRC-RS 414 TLI +I++P ++ TF ++ S+N +++ G+ LAIGLLVD+AIVV+EN++R Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 415 EGMSKLDAAVTGTKEVAGAIFASTMTTLAVFVPLVFVDGIAGALFSDQALTVTFALLASL 474 + + +A ++ GA+ M AVF+P+ F G GA++ ++T+ A+ S+ Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 475 LVALTSIPMLASREGFTALPELIKKTPKEKPTTKLGKLKHYSATVFSFPIVLIFSYLPSV 534 LVAL P L + L+K E K Sbjct: 483 LVALILTPALCAT--------LLKPVSAEHHENK-------------------------- 508 Query: 535 LLTLALVIGRFFSWLLGLVMRPLSSGFNFVYHAIESVYHKLLAMALRKQVATLLLTIGIT 594 G FF W FN + + Y + L LL+ I Sbjct: 509 --------GGFFGW------------FNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIV 548 Query: 595 GACISLLPRLGMELIPPMNQGEFYVEILLPPGTAVGETDKVLQQLAMSI--KDRPEVKHA 652 + L RL +P +QG F I LP G T KVL Q+ ++ V+ Sbjct: 549 AGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESV 608 Query: 653 YSQAGSGGLMTSDTARGGENWGRLQVVL---SDHTAYHQVTQVLRDTARRIPELEAKIEQ 709 ++ G + +N G V L + + + A+ KI Sbjct: 609 FTVNGFS------FSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMEL---GKIRD 659 Query: 710 PELFSFKTPLEIEL---SGYDLHLLKRSADNLVKALSASDRFA-----------DVNTSL 755 + F P +EL +G+D L+ ++ A ++ V + Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 756 RDGQPELSIRFDHARLAALGMDAPTVANRIAQRVGGTVASQYTVRDRKIDILVRSELDER 815 + + + D + ALG+ + I+ +GGT + + R R + V+++ R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 816 DQISDIDALIINPNSQQPIALSAVAEVSLQLGPSAINRISQQRVALVSANLAYG-DLSDA 874 D+D L + + + + SA G + R + + A G DA Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 875 VAEAQQILSAQVLPASVQARFGGQNEEMEHSFQSLKIALILAVFLVYLVMASQFESLLHP 934 +A + + S LPA + + G + + S + ++ +V+L +A+ +ES P Sbjct: 840 MALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIP 897 Query: 935 LLILFAVPMALAGSVLGLYITQTHLSVVVFIGLIMLAGIVVNNAIVLVDRINQL-RTEGV 993 + ++ VP+ + G +L + V +GL+ G+ NAI++V+ L EG Sbjct: 898 VSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGK 957 Query: 994 DKLEAIKVAAKSRLRPIMMTTLTTTLGLLPMALGLGDGSEVRAPMAITVIFGLSLSTLLT 1053 +EA +A + RLRPI+MT+L LG+LP+A+ G GS + + I V+ G+ +TLL Sbjct: 958 GVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLA 1017 Query: 1054 LIVIPVLYALFDRK 1067 + +PV + + R Sbjct: 1018 IFFVPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.0 bits (96), Expect = 6e-06 Identities = 13/53 (24%), Positives = 29/53 (54%) Query: 72 GLIEAINVEEGDRVQKGQILAVIDAKRQQYDLDRSEAEVKIIEQELNRLKKMS 124 +++ I V+EG+ V+KG +L + A + D ++++ + E R + +S Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Score = 40.2 bits (94), Expect = 9e-06 Identities = 36/202 (17%), Positives = 80/202 (39%), Gaps = 24/202 (11%) Query: 91 LAVIDAKRQ----QYDLDRSEAEVKIIEQELNRLK---KMSNKEFIS--ADSMAKLEYNL 141 AV++ + + +L +++++ IE E+ K ++ + F + D + + N+ Sbjct: 252 HAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNI 311 Query: 142 QAAIAKRDLAELQVKESHVVSPINGIIAKRYVKAGNMAKEFGD-LFYIV-NQDELHGIVH 199 + E + + S + +P++ + + V + L IV D L Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTAL 371 Query: 200 LPEQQLTSLRLGQEAQV-FS--NQQSKNAIHAKVLRISP--VVDPQSGT-FKVTLAVP-- 251 + + + + +GQ A + + KV I+ + D + G F V +++ Sbjct: 372 VQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEEN 431 Query: 252 -----NQNAHLKAGMFTRVELK 268 N+N L +GM E+K Sbjct: 432 CLSTGNKNIPLSSGMAVTAEIK 453
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 30.3 bits (68), Expect = 0.002 Identities = 12/43 (27%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 4 TIKRNQPPAMPDRFYQVIEKELANVDPKDANAITLNFRDPDYS 46 T+ + + +IE+EL + KD+ + L R+PD+S Sbjct: 162 TLTQGVTTSARVPNGAIIERELPS-KFKDSVNLVLQLRNPDFS 203
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 326 bits (837), Expect = e-108 Identities = 120/344 (34%), Positives = 176/344 (51%), Gaps = 28/344 (8%) Query: 192 FDDIITLDPEMLLLKAKAQVLASHEVSVLICGESGTGKEMFARAIHNASARRDKPFVAVN 251 ++ M + L +++++I GESGTGKE+ ARA+H+ RR+ PFVA+N Sbjct: 136 GMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAIN 195 Query: 252 CGAFPSELIDSILFGHKKGAFTGAVSDKVGVFELAHSGTLFLDEFGELDSSAQVRLLRVL 311 A P +LI+S LFGH+KGAFTGA + G FE A GTLFLDE G++ AQ RLLRVL Sbjct: 196 MAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVL 255 Query: 312 QDGKFTRLGDSKERSSNFRLITATNRDLMADVSKGRFREDLFYRVAIGVLSLPPLRSRQS 371 Q G++T +G S+ R++ ATN+DL +++G FREDL+YR+ + L LPPLR R Sbjct: 256 QQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAE 315 Query: 372 DLDHLADQFTAMLTQEYPSLGGKKISTAAKKIISNHRWPGNIRELKATILRAALWSETAV 431 D+ L F +E L K+ A +++ H WPGN+REL+ + R V Sbjct: 316 DIPDLVRHFVQQAEKEG--LDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDV 373 Query: 432 LEDVDILRAILSTL---------QNSESILERD----------------ISKGVDIKSII 466 + I + S + S S+ + ++ Sbjct: 374 ITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVL 433 Query: 467 DLVERHYLERGLAFTSGNKRKTALLLGYNNHQTLNNRLKKLGLE 510 +E + L T GN+ K A LLG N TL ++++LG+ Sbjct: 434 AEMEYPLILAALTATRGNQIKAADLLGL-NRNTLRKKIRELGVS 476
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 28.2 bits (62), Expect = 0.033 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 4/66 (6%) Query: 46 ALGQFANNFLQAVGILKPDEDVKQLGERALQAAQDGITPEM----YDDFDDYVQALRNFE 101 L + F + GI E +L E+ Q A G P++ +D F Y Q+ E Sbjct: 45 GLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAE 104 Query: 102 IDPDKA 107 I PDKA Sbjct: 105 ITPDKA 110
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 30.6 bits (69), Expect = 0.005 Identities = 17/68 (25%), Positives = 29/68 (42%), Gaps = 7/68 (10%) Query: 176 NAILRRVDTEQLMSYLPALFPRVFTVIDGNELALLAGRIEPFKIANPYPEPSPETLYQLQ 235 + + EQ L V TV + + +I P+ I P+ E + +TL +L Sbjct: 51 IHVFENLTDEQ-----KELIDTVLTVQNREDAESFLLKINPYVI--PFQEVTAQTLKKLF 103 Query: 236 RQFKKLPI 243 + KKL + Sbjct: 104 PKAKKLKL 111
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.8 bits (80), Expect = 4e-04 Identities = 12/75 (16%), Positives = 29/75 (38%), Gaps = 10/75 (13%) Query: 104 ELQALEQQLAQAHGANSQLEQELQQLQ----------SKLYEQQNKNLTLENALTSATAK 153 E + ++ + + + L + EQ+NK + N L ++ Sbjct: 215 ERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQ 274 Query: 154 LKQLEAQYQQAQQAL 168 L+Q+E++ A++ Sbjct: 275 LEQIESEILSAKEEY 289
>cdtoxinb#Cytolethal distending toxin B signature. Length = 269 Score = 27.7 bits (61), Expect = 0.034 Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 1/64 (1%) Query: 93 LSKERGGQALDCQCLGIIPTEIDELDRQTLKAEGLPLPHMGWNQLTFSNPSQVHPLFAGV 152 +S E L Q G P+ + + + G+P+ + WN T S P QV+ F+ V Sbjct: 49 ISGENAVDILAVQEAGSPPSTAVDTGTL-IPSPGIPVRELIWNLSTNSRPQQVYIYFSAV 107 Query: 153 PAGS 156 A Sbjct: 108 DALG 111
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 31.9 bits (72), Expect = 0.001 Identities = 31/137 (22%), Positives = 52/137 (37%), Gaps = 23/137 (16%) Query: 2 KSAVLVIDVQSIL---FDPEPQPFESQIVLAKINEVTKLARAKSVPVIFIQHEQPKSVIE 58 ++ +L+ D+Q+ F P + A I ++ +PV++ QP S Sbjct: 30 RAVLLIHDMQNYFVDAFTAGASPVTE--LSANIRKLKNQCVQLGIPVVYTA--QPGSQNP 85 Query: 59 YESA------GWALQSS---------LVIQTGDYFVRKTTPDSFLNTNLQSVLNELDVDS 103 + A G L S L + D + K +F TNL ++ + D Sbjct: 86 DDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQ 145 Query: 104 LIVCG-YASEFCVDTTI 119 LI+ G YA C+ T Sbjct: 146 LIITGIYAHIGCLVTAC 162
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.8 bits (228), Expect = 9e-24 Identities = 36/128 (28%), Positives = 63/128 (49%), Gaps = 7/128 (5%) Query: 2 SRILLVDDDPLFRVWLTDALKTQGHEVECAINGIEGLKRIRSFMPDIIMLDLIMPQMDGF 61 + IL+ DDD R L AL G++V N + I + D+++ D++MP + F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 SLLE---ARDCMTPIMMLSARDNEEDRIRCYELGADDFLTKPFSIKELLVRLHALERRLI 118 LL P++++SA++ I+ E GA D+L KPF + EL+ + R + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELI----GIIGRAL 119 Query: 119 SRPPEQMA 126 + P + + Sbjct: 120 AEPKRRPS 127
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 25.7 bits (56), Expect = 0.028 Identities = 7/34 (20%), Positives = 17/34 (50%) Query: 1 MTDINQVIDQMPEEVYERLRSAAELGKWEDGTVL 34 + +N++ E++Y + + GK+ED + Sbjct: 25 IAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKV 58
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 113 bits (284), Expect = 1e-36 Identities = 31/89 (34%), Positives = 56/89 (62%), Gaps = 1/89 (1%) Query: 2 TKSELIEKLATRQSQLSAKEVEGAIKEMLEQMATTLESGDRIEIRGFGSFSLHYRAPRTG 61 K +LI K+A ++L+ K+ A+ + +++ L G+++++ GFG+F + RA R G Sbjct: 3 NKQDLIAKVA-EATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 62 RNPKTGSSVELEGKYVPHFKPGKELRERV 90 RNP+TG ++++ VP FK GK L++ V Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 95.5 bits (237), Expect = 1e-25 Identities = 73/258 (28%), Positives = 120/258 (46%), Gaps = 14/258 (5%) Query: 10 QGKNVVVVGGTSGINLAIANAFALAGANVAVASRSQDKIDAAV--LQLKQSNPDGIHLGV 67 +GK + G GI A+A A GA++A + +K++ V L+ + + + Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA-- 64 Query: 68 SFDVRDLAAVEQGFDTIASEFGFIDVLVSGAAGNFPATAAKLSANGFKAVMDIDLLGSFQ 127 DVRD AA+++ I E G ID+LV+ A P LS ++A ++ G F Sbjct: 65 --DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 128 VLK-TAYPLLRRPQGNIIQISAPQASIAMPMQAHVCAAKAGVDMLTRTLAIEWGCEGIRI 186 + + ++ R G+I+ + + A + A ++KA M T+ L +E IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 187 NSIVPGPIAGTEGFNRLAPSAALQQGVAQS-------VPLKRNGEGQDIANAAMFLGSEL 239 N + PG ++ A +Q + S +PLK+ + DIA+A +FL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 240 ASYITGVVLPVDGGWSLG 257 A +IT L VDGG +LG Sbjct: 243 AGHITMHNLCVDGGATLG 260
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 30.5 bits (69), Expect = 0.015 Identities = 35/158 (22%), Positives = 62/158 (39%), Gaps = 22/158 (13%) Query: 22 LLLGSMLSILLPTQAIAAIHPLDESTFAKQIADIAPRHS-QVALLARDLSTNTLLYSQQA 80 ++ + ++ L A +QI + S +V ++ DL++ L + +A Sbjct: 7 CIISLLATLPLAVHASPQPL--------EQIKLSESQLSGRVGMIEMDLASGRTLTAWRA 58 Query: 81 DTLFIPASTQKVLT--AVTAMASLGPDF--RYVT----ELWSDAPIRQGHIAGSVYLRFS 132 D F ST KV+ AV A G + R + +L +P+ + H+A + + Sbjct: 59 DERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEL 118 Query: 133 GDPTLTQDDLKA---LFAHLQKQGITSIEGHLYLIGDK 167 +T D A L A + G + L IGD Sbjct: 119 CAAAITMSDNSAANLLLATV--GGPAGLTAFLRQIGDN 154
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 32.3 bits (73), Expect = 0.003 Identities = 14/55 (25%), Positives = 27/55 (49%), Gaps = 1/55 (1%) Query: 246 SEPFAAYNAVKDWLNESKITEGHLFRSISRDGKTLRPYQVSDNVT-SKSSLIRNS 299 ++ YN V +N +K+ G + + +GK Y +DN+ +K +L N+ Sbjct: 331 TDKVTRYNTVTVAMNTTKLANGISYYEVIENGKATGKYINADNIDGTKRTLKHNA 385
>FLAGELLIN#Flagellin signature. Length = 507 Score = 29.2 bits (65), Expect = 0.024 Identities = 14/71 (19%), Positives = 36/71 (50%), Gaps = 6/71 (8%) Query: 19 SINDTATQLKTSSSAVSRTLKTLRHIFEDELLTRK--NGKMELTTKAIALREKVSRIIEE 76 + ND + +T+ A++ L+ + E L+ + NG + ++++++ + +EE Sbjct: 66 NANDGISIAQTTEGALNEINNNLQRVRE---LSVQATNGTNSDSDLK-SIQDEIQQRLEE 121 Query: 77 IESLTENESFN 87 I+ ++ FN Sbjct: 122 IDRVSNQTQFN 132
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.1 bits (169), Expect = 2e-14 Identities = 36/199 (18%), Positives = 70/199 (35%), Gaps = 19/199 (9%) Query: 255 KILLVDDQQSMVDYFSSLLRSHGLMVKGMTKPEQVLPTLEQFEPDLFIFDLYMPDVNGLE 314 IL+ DD ++ + L G V+ + + + + DL + D+ MPD N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 315 LAKMIRQLDKYSSSPILVLSSDDTMQNKVSIIQAGSDDLISKQTAP--SLFVTQVISRAQ 372 L I++ P+LV+S+ +T + + G+ D + K + + Sbjct: 65 LLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 373 RGHDIRSSASRDSLTGLLNHTQILVAARRCFNLAKRINSSVCIAMLDLDHFKQVNDTYGH 432 + + L+ + + R + + ++ I G Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT--------------GE 168 Query: 433 SGGDKVLLAFAHLLQQSLR 451 SG K L+A A L R Sbjct: 169 SGTGKELVARA-LHDYGKR 186 Score = 56.0 bits (135), Expect = 2e-10 Identities = 26/123 (21%), Positives = 54/123 (43%), Gaps = 1/123 (0%) Query: 131 RIAIIEDDNNVGAMITKQLHEFGFNVQHFLNFTDFLEIQNTSPFDLILLDLILPDYTEEA 190 I + +DD + ++ + L G++V+ N DL++ D+++PD Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 191 LFTAATEFEKHNTRVFVLSSRGDFEMRLLAIRANVSEYFVKPAETTLLVRKIHQWLKMSE 250 L + + + V V+S++ F + A +Y KP + T L+ I + L + Sbjct: 65 LLPRIKK-ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 251 KQP 253 ++P Sbjct: 124 RRP 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.2 bits (164), Expect = 2e-14 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 7/107 (6%) Query: 3 IKVLVVDDSALIRNLLGQMIE-ADSELSLVGMAADAYMAKDMVNQHRPDVITLDIEMPKV 61 +LV DD A IR +L Q + A ++ + AA + D++ D+ MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATL---WRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGLTFLDRLMKARPTAVVMISSLTEEG-ADATFNALALGAVDFIPKP 107 + L R+ KARP V++ ++ + A GA D++PKP Sbjct: 61 NAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP 105
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 9e-05 Identities = 15/70 (21%), Positives = 32/70 (45%), Gaps = 10/70 (14%) Query: 452 EIDKGMIEKLVDPLT--HLVRNSLDHGIEKPEKRLAAGKTEAGVLSLKASQRGGSIVIAV 509 +I+ +++ V P+ LV N + HGI + + G + LK ++ G++ + V Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIAQ--------LPQGGKILLKGTKDNGTVTLEV 296 Query: 510 HDDGGGLNRE 519 + G + Sbjct: 297 ENTGSLALKN 306
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.0 bits (213), Expect = 5e-23 Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 3/122 (2%) Query: 1 MSK-KILIVDDSAAIRQMVEATLKSANYQVVLAKDGREALDLCGGQRFDFILTDQNMPRM 59 M+ IL+ DD AAIR ++ L A Y V + + D ++TD MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 DGLTLIKSLRGMSAFMRTPIVMLTTEAGEDMKAQGRAAGATGWMVKPFDPQKLLAITAKV 119 + L+ ++ A P+++++ + + GA ++ KPFD +L+ I + Sbjct: 61 NAFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 LG 121 L Sbjct: 119 LA 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.6 bits (199), Expect = 3e-18 Identities = 32/104 (30%), Positives = 51/104 (49%) Query: 8 ILVIDDDLVTNQILTAFIHSKGWGVITCCNLEEAYEEINQQNIELILLDYYLPDGTALTL 67 ILV DDD +L + G+ V N + I + +L++ D +PD A L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 68 LERLRYREPTVPVIVISADNEYQKILSCFRLGALDFIIKPINLE 111 L R++ P +PV+V+SA N + + GA D++ KP +L Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>PF07520#Virulence protein SrfB Length = 1041 Score = 30.7 bits (69), Expect = 0.020 Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 7/77 (9%) Query: 266 KAKRFTPAQDQQLQKYLVRRVLIEQDDNFKD---WADNLLPEMKSDDMFERRLRWAIREQ 322 K + F D + ++R+ ++D N D W + L EM D R +I E+ Sbjct: 175 KPREFRLVSDPGAMSWFLQRLEADEDGNAVDLQLWVSDWLKEMFLDFKRAERPGRSISEE 234 Query: 323 DN----THIARYLDLLS 335 + H ARYL L Sbjct: 235 NLPHMFEHWARYLSYLQ 251
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 36.6 bits (84), Expect = 3e-04 Identities = 21/68 (30%), Positives = 38/68 (55%), Gaps = 7/68 (10%) Query: 594 ALEEAKIQ-QAIAEQEAIAAQAKAA--EEAALAKAKAEAEAEAERQRL----EQEEQMKA 646 ALEEA + A+ + ++K +E A +AK EAEA+A +++L E+ +++A Sbjct: 401 ALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRA 460 Query: 647 SEQSQPET 654 + S +T Sbjct: 461 GKASDSQT 468 Score = 34.7 bits (79), Expect = 0.001 Identities = 21/82 (25%), Positives = 33/82 (40%), Gaps = 13/82 (15%) Query: 596 EEAKIQQAIAEQEAIAAQAKAAEEAALAKAK--------AEAEAEAERQRLEQEEQMKAS 647 EA+ AE+ + Q A + A+ + EAE Q+LE EQ K S Sbjct: 286 LEAEKAALEAEKADLEHQ-SQVLNANRQSLRRDLDASREAKKQLEAEHQKLE--EQNKIS 342 Query: 648 EQSQPETGSQEAIATSDESLAK 669 E S+ + + S E+ + Sbjct: 343 EASR--QSLRRDLDASREAKKQ 362 Score = 32.0 bits (72), Expect = 0.008 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 10/88 (11%) Query: 592 VEA-LEEAKIQQAIAEQEAIAAQAK--AAEEAALAKAKAEAEAEAERQRLEQ-----EEQ 643 +EA ++ + Q I+E + + A+ EA KA EA ++ LE+ EE Sbjct: 363 LEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEES 422 Query: 644 MKASEQSQPETGSQ-EAIATS-DESLAK 669 K +E+ + E ++ EA A + E LAK Sbjct: 423 KKLTEKEKAELQAKLEAEAKALKEKLAK 450 Score = 30.8 bits (69), Expect = 0.020 Identities = 16/61 (26%), Positives = 29/61 (47%), Gaps = 4/61 (6%) Query: 611 AAQAKAAEEAALAKAKAEAE-AEAERQRLEQEEQMKASEQSQPETGSQEAIATSD-ESLA 668 + +AK EA K + + + +EA RQ L + + AS +++ + A S +L Sbjct: 356 SREAKKQLEAEHQKLEEQNKISEASRQSLRR--DLDASREAKKQVEKALEEANSKLAALE 413 Query: 669 K 669 K Sbjct: 414 K 414
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 38.5 bits (89), Expect = 8e-06 Identities = 27/164 (16%), Positives = 56/164 (34%), Gaps = 7/164 (4%) Query: 21 WEQRRDYLTQVALRSLRGHKTFDLCRSHLVQVSQISKGTIYNHFTTEADLIVAVASAQYD 80 ++ R ++ VALR + + + +++G IY HF ++DL + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 81 EWLCAAKQ-DVQRYPDPFSRF--LYHHCFRLHQVLSQQRFVIERIMPNQTLLFEATESCR 137 + + DP S + H ++R ++E I+ ++ + Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLME-IIFHKCEFVGEMAVVQ 127 Query: 138 QRFETLFDEYHQWNRNTISEV---GDIPGFNRTELVMDYLRGAM 178 Q L E + T+ +P T +RG + Sbjct: 128 QAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 2e-15 Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 2/119 (1%) Query: 10 DKATILLIDDHPMLRNGVKQLIGMADNLCIVAEASCGKDGIILATQLDPDLILLDLNMPE 69 ATIL+ DD +R + Q + A + D DL++ D+ MP+ Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSN--AATLWRWIAAGDGDLVVTDVVMPD 59 Query: 70 FNGLETLTKLRECELSSRIIVFTVSNYEGDIVNAFKYGADGYLLKDMEPEDLLQSIQQA 128 N + L ++++ ++V + N + A + GA YL K + +L+ I +A Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.033 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 1/56 (1%) Query: 126 NTTPFSIFVIIALLCGFGGANF-ASSMANISFFYPKDKQGSALGLNGGLGNLGVSV 180 + FS+ ++ + G G A F A M ++ + PK+ +G A GL G + +G V Sbjct: 99 GHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGV 154
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 35.8 bits (82), Expect = 1e-04 Identities = 39/133 (29%), Positives = 58/133 (43%), Gaps = 16/133 (12%) Query: 216 TVNVGDF---NGVGTGAGEKNFNLNVTC--QSGT-KAYISFSDAYNSSNSSDSLSTLTST 269 VN GD N V +G +K+F +++ C GT K I+ + +S L TST Sbjct: 45 EVNWGDIEIQNLVQSGGNQKDFTVDMNCPYSLGTMKVTITSNGQTGNS----ILVPNTST 100 Query: 270 TSADGVNIQILSNNWGG---AIVLNTPFYVVGADDSAAASYTIPFSAR--YIQVDPVLTA 324 S DG+ I + ++N G A+ L + G A + I A+ Y L A Sbjct: 101 ASGDGLLIYLYNSNNSGIGNAVTLGSQV-TPGKITGTAPARKITLYAKLGYKGNMQSLQA 159 Query: 325 GTVEAKTIVVMTY 337 GT A +V +Y Sbjct: 160 GTFSATATLVASY 172
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 617 bits (1593), Expect = 0.0 Identities = 224/855 (26%), Positives = 388/855 (45%), Gaps = 50/855 (5%) Query: 13 SVFPIFFILFGSFTFAKEN--EMIEFDSAFFNVNDASLI--QKFAYSNYVPSGVYPADLF 68 + F + + +F + F+ F + ++ +F +P G Y D++ Sbjct: 24 AGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIY 83 Query: 69 VNGSFLKKVSLEVKEDGGK--SRPCIDMNILNSLGIKESILIESDNLIKD-CIVLEEVIV 125 +N ++ + + PC+ L S+G+ + + + L D C+ L +I Sbjct: 84 LNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIH 143 Query: 126 GSAVNFTMGMSKLDIQVPQIYLDKVVRGYVDPAEWERGISAAYISYDLFGV---SPNDVK 182 + +G +L++ +PQ ++ RGY+ P W+ GI+A ++Y+ G + Sbjct: 144 DATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGN 203 Query: 183 NFNAYFD--SGININGWYFKHKGMYSWNEYTGE-----QYNALDSYLYRPVASIKGNVVL 235 + AY + SG+NI W + +S+N ++ ++++L R + ++ + L Sbjct: 204 SHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTL 263 Query: 236 GKKNTNGRLFDTVPLLGMQIYDDQNMLADSQKGYAPEIFGVAKTNAIVKVEQNGRIIYET 295 G T G +FD + G Q+ D NML DSQ+G+AP I G+A+ A V ++QNG IY + Sbjct: 264 GDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNS 323 Query: 296 LVSPGEFLINDLYPTGYGGNLNVIILEADGTEQRFSVPYESMAQLLRPNTSRYSFSIGQY 355 V PG F IND+Y G G+L V I EADG+ Q F+VPY S+ L R +RYS + G+Y Sbjct: 324 TVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEY 383 Query: 356 KNDRLS-FTPMLIEGTYELGINNFVTGYWGGQANEDFLSLQGGLALGT-SLGTFSFGGTQ 413 ++ P + T G+ T Y G Q + + + G+ +LG S TQ Sbjct: 384 RSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQ 443 Query: 414 SYAFL--DENYSGQSYELKYSKNIFSSGTNLSLGAYKYSTKEYMDYQTAMLYLDNIRRGY 471 + + L D + GQS Y+K++ SGTN+ L Y+YST Y ++ N Sbjct: 444 ANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIE 503 Query: 472 L--------------YNDLYNSKNRYLVTVGQSFPEGYGNLYLSGVFENFWNETNYSRQY 517 YN YN + + +TV Q LYLSG + +W +N Q+ Sbjct: 504 TQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSNVDEQF 562 Query: 518 QVSYNNQYKRLSWGVSVSRNEDQYG-QYQTNYALSLSIPLGF------EGELRDSRVRLN 570 Q N ++ ++W +S S ++ + AL+++IP + + R + + Sbjct: 563 QAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYS 622 Query: 571 LNRDSDGYQQAQVGLSDVVGEEKLLSYDVSVS-----NDESSNSFNGNASYVSPIAKLSA 625 ++ D +G G+ + E+ LSY V + S ++ +Y + Sbjct: 623 MSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANI 682 Query: 626 NASKGNNYKSYGFGLSGTLVGHSGGVTLSPYSGNTFALVEAKGMEGATVSGYKGIKINNL 685 S ++ K +G+SG ++ H+ GVTL +T LV+A G + A V G++ + Sbjct: 683 GYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR 742 Query: 686 GHAVVPNLRPYQVNHIHVDPNGTSKNASLSNTVNKTVPYDSAIVKLQYGTEIGFSILINS 745 G+AV+P Y+ N + +D N + N L N V VP AIV+ ++ +G +L+ Sbjct: 743 GYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTL 802 Query: 746 SFKGDALPFGADVIDENGLNIGNVAQGSIVFARTKSSNGILKV--NIKNGEYCSIKYDVN 803 + LPFGA V E+ + G VA V+ G ++V + +C Y + Sbjct: 803 THNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLP 862 Query: 804 KNKSKGTLNILNVDC 818 + L L+ +C Sbjct: 863 PESQQQLLTQLSAEC 877
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 44.8 bits (106), Expect = 3e-07 Identities = 19/130 (14%), Positives = 49/130 (37%), Gaps = 18/130 (13%) Query: 180 MPGKKVLIVDDSSTARRQVRETLGQLGIEIIEASDGLQALHLLQKWRDEGKNVAKELLMM 239 M G +L+ DD + R + + L + G ++ S+ + ++ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI---AAGDGDLV------ 51 Query: 240 ITDAEMPEMDGYKLTYEVRNDKAMAD-LFITLNTSLSGSFNHAMVE--KVGCDRFISK-F 295 +TD MP+ + + L ++ + L ++ + ++ + G ++ K F Sbjct: 52 VTDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNTF-----MTAIKASEKGAYDYLPKPF 106 Query: 296 QPDLLVEVVQ 305 L+ ++ Sbjct: 107 DLTELIGIIG 116
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 52.0 bits (124), Expect = 1e-08 Identities = 46/263 (17%), Positives = 82/263 (31%), Gaps = 16/263 (6%) Query: 838 PAQFVPNDALGDAQDYPAPTAQTAEAAETTEAKATEVAAEPTVTSPAAVVETADVSVVAE 897 P N + Q + + + E V PA + VAE Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 898 TNKAVE--TEVVESVATEQVA--KLKAEVAVTEAPADTAVNNKPETSVKAEDVAVEPAKA 953 +K E E ATE A + A+ A + A+T N ++ + ++ K Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 954 VEAVTEAIVTPAETPVAQAKTETVAVEAVAPEVEKAEVKDAVKSVASAPMAKPAPIV--- 1010 V + ET +T V V +V + + + P + P V Sbjct: 1103 TATVEKEEKAKVET------EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK 1156 Query: 1011 KPQAKPVVTQAVAAPAAETVVSKPKAASRFGSMVSSEMTKPTVEVRTQVEVPKGREYDNT 1070 +PQ++ T PA ET + + + + VE + N+ Sbjct: 1157 EPQSQTNTTADTEQPAKETSSNVEQPVT---ESTTVNTGNSVVENPENTTPATTQPTVNS 1213 Query: 1071 ASAEVTAPKLKQSNSAESDMARP 1093 S+ + ++S + P Sbjct: 1214 ESSNKPKNRHRRSVRSVPHNVEP 1236 Score = 48.9 bits (116), Expect = 1e-07 Identities = 50/304 (16%), Positives = 95/304 (31%), Gaps = 18/304 (5%) Query: 731 RRQPRKDAAVANETVEATDAASQVEANAEVSAEKPVVENRAEAPADVTEVKTEAETDADN 790 R Q + D S N E++ PA T +T ET A+N Sbjct: 988 RNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPP---PAPATPSET-TETVAEN 1043 Query: 791 AELSADADDKAKRESRDGQRRSRRSPRHLRAAGQRRRRDEDEQGVSAPAQFVPNDALGDA 850 ++ + +K ++++ + ++R A + + + + AQ + Sbjct: 1044 SKQESKTVEKNEQDATETTAQNR------EVAKEAKSNVKANTQTNEVAQSGSETK--ET 1095 Query: 851 QDYPAPTAQTAEAAETTEAKATEVAAEPTVTSPAAVVETADVSVVAETNKAVETEVVESV 910 Q T E E + + + P VTS + + +V + A E + ++ Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 911 ATEQVAKLKAEVAVTEAPADTAVNN--KPETSVKAEDVAVEPAKAVEAVTEAIVTPAETP 968 ++ A TE PA +N +P T + + E T A P Sbjct: 1156 --KEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNS 1213 Query: 969 VAQAKTETVAVEAVAPEVEKAEVKDAVKSVASAPMAKPAPIVKPQAKPVVTQAVAAPAAE 1028 + K + +V V+ A S + V++ A A Sbjct: 1214 ESSNKPKNRHRRSVRS--VPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFV 1271 Query: 1029 TVVS 1032 + Sbjct: 1272 ALNV 1275 Score = 45.1 bits (106), Expect = 2e-06 Identities = 59/335 (17%), Positives = 94/335 (28%), Gaps = 32/335 (9%) Query: 531 QKVEQAAAPVANKVEATEPGFFSKLFSAIGAFFSSSDKPAAEKTTETKKSDSQTANANRR 590 Q V+ N ++A P S I + P A T S+T Sbjct: 990 QTVDTTNITTPNNIQADVPSVPSN-NEEIARVDEAPVPPPAPAT------PSETTETVAE 1042 Query: 591 NRRNDTRRT-RNNQDADKAKEGTREPRTRNAKKSADAPQAQERPAREKDENAKRTKPEPK 649 N + +++ +N QDA + RE Q E A+ E + E K Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEV-AQSGSETKETQTTETK 1101 Query: 650 SRNQAPKEVVAESQDDTPKQEVARERRQRRNMRRKVRIDNANETTEAPIQEEVVLAEVAA 709 KE A+ + + QEV + Q + + AE A Sbjct: 1102 ETATVEKEEKAKVETEK-TQEVPKVTSQVSPKQEQSE-------------TVQPQAEPAR 1147 Query: 710 VNAANTDVATEPQAETKAPRSRRQPRKDAAVANETVEATDAASQVEANAEVSAEKPVVEN 769 N T EPQ++T QP K+ + E + + E Sbjct: 1148 ENDP-TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPE--NTTP 1204 Query: 770 RAEAPADVTEVKTEAETDADNAELSADADDKAKRESRDGQRRSRRSPRHLRAAGQRRRRD 829 P +E + + + S + + S + RS L Sbjct: 1205 ATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTS-----SNDRSTVALCDLTSTNTNA 1259 Query: 830 EDEQGVSAPAQFVPNDALGDAQDYPAPTAQTAEAA 864 A AQFV + + + E Sbjct: 1260 VLSD-ARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.9 bits (114), Expect = 2e-07 Identities = 19/200 (9%), Positives = 53/200 (26%), Gaps = 30/200 (15%) Query: 519 QPAVSHEDLPTDLQLQAAQDAEALALDNLNKARAEYRGLQKQLEAQQQQANDLATALGDK 578 + L + Q + A + + R ++ + + ++ + Sbjct: 122 DVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSE 181 Query: 579 VELSLESHSQTLERLMQQAKQADDAAQALQLLQQQIKTLQQQESTLAQQLELERE----- 633 E+ + E+ Q L + + T+ + + +E+ Sbjct: 182 EEVLRLTSLIK-EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDF 240 Query: 634 ------------RYREQEGKVERLSGQLAEKALRIPEEYRTLDVLNQAIANNQQQLEQI- 680 EQE K +L ++ + + I + +++ + + Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ-------IESEILSAKEEYQLVT 293 Query: 681 ----KRQIDVLRTAQQQATQ 696 +D LR Sbjct: 294 QLFKNEILDKLRQTTDNIGL 313 Score = 40.6 bits (95), Expect = 3e-05 Identities = 36/214 (16%), Positives = 72/214 (33%), Gaps = 25/214 (11%) Query: 192 DTLKAKAADIRNLVKEQRARRDGILQTAALTSDDELTAELSRIEPEFAAATAAKEQSVAA 251 DTLK +++ ++ +++ R + L+ EL P+ E+ V Sbjct: 135 DTLKTQSSLLQARLEQTRYQ--------ILSRSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 252 HLAALKQRDSAQQLFAEFTRLQELQAEALSLNEQQAQIATQTTRLEVAKQALRV------ 305 + +K+ Q + + + L++++A+ T R+ + RV Sbjct: 187 LTSLIKE-----QFSTWQNQKYQKELN---LDKKRAERLTVLARINRYENLSRVEKSRLD 238 Query: 306 --KPLLDNALSREQEASVAAAQRDSAQLTLDAAKLALSHAETAAQEIIPLEHKLREVEQQ 363 LL + + A L K L E+ E++L + Sbjct: 239 DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAK-EEYQLVTQLFK 297 Query: 364 NSHLSALVPQLAEFASLEQALAQAKEILQHTKLQ 397 N L L L LA+ +E Q + ++ Sbjct: 298 NEILDKLRQTTDNIGLLTLELAKNEERQQASVIR 331 Score = 30.2 bits (68), Expect = 0.044 Identities = 28/200 (14%), Positives = 65/200 (32%), Gaps = 16/200 (8%) Query: 617 LQQQESTLAQQLELERERYREQEGKVERLSGQLAEKALRIPEEYRTLDVLNQAIANNQQQ 676 + +S+L Q LE+ RY+ +E + + + + + + + ++Q Sbjct: 136 TLKTQSSLLQAR-LEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194 Query: 677 LEQIKRQIDVLRTAQQQATQQSVAAQTALSAAIERCHATVELQAQAQQTLQTALDNAGFI 736 + Q + + + A I R ++ + L + I Sbjct: 195 FSTWQNQKYQKELNLDKKRAERLTVL----ARINRYENLSRVEKSRLDDFSS-LLHKQAI 249 Query: 737 DRDALREALLTDEQMQTLAEGKETYHRQCALNQSQLTQLTTKLSESTSPDLDALEALLTE 796 + A+ EQ E + + +SQL Q+ +++ + + E Sbjct: 250 AKHAVL------EQENKYVE----AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNE 299 Query: 797 RLAQLKNAEELWSQLNTRLT 816 L +L+ + L L Sbjct: 300 ILDKLRQTTDNIGLLTLELA 319
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.1 bits (65), Expect = 0.019 Identities = 16/83 (19%), Positives = 30/83 (36%), Gaps = 1/83 (1%) Query: 198 YFNQKKYKKAVGVLEVMVPLFPDDGRLWVQLAQFYLMVEDYDKSLATYDLAYRNGFLDTG 257 + KY+ A V + + L D R ++ L + YD ++ +Y + Sbjct: 46 QYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPR 105 Query: 258 ANITRLAQLMAQKGAPYKAAKVF 280 A+ + QKG +A Sbjct: 106 FPFHA-AECLLQKGELAEAESGL 127
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 108 bits (272), Expect = 2e-31 Identities = 37/169 (21%), Positives = 64/169 (37%), Gaps = 10/169 (5%) Query: 39 TPVIEITMDRQDSKAQNKPRVVPKPPPPPEQPQKPDTTPPDTSSNID----TSMSFNMGG 94 P E + K PKP P P+ P S N Sbjct: 75 EPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAP 134 Query: 95 VEAGGHGTGGFKLGNMMTRDGDATPIVRIEPQYPIAAARDGKEGWVQLRFTINELGGVDD 154 + + + R +PQYP A EG V+++F + G VD+ Sbjct: 135 ARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDN 194 Query: 155 VEIINAEPKRLFDKEAIRALKKWKYKPKIVDGKPLKQPGMTVQLDFTLD 203 V+I++A+P +F++E A+++W+Y+P G+ V + F ++ Sbjct: 195 VQILSAKPANMFEREVKNAMRRWRYEP------GKPGSGIVVNILFKIN 237
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.020 Identities = 13/28 (46%), Positives = 16/28 (57%) Query: 42 TLAIVGEAGSGKSTLARILVGAEPRSGG 69 TL I GE+G+GK +AR L R G Sbjct: 162 TLMITGESGTGKELVARALHDYGKRRNG 189
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 119 bits (300), Expect = 4e-39 Identities = 53/88 (60%), Positives = 69/88 (78%) Query: 2 NKSELIEKIASGADISKAAAGRALDSFIAAVTEGLKEGDKISLVGFGTFEVRERAERTGR 61 NK +LI K+A +++K + A+D+ +AV+ L +G+K+ L+GFG FEVRERA R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGEEIKIAAAKIPAFKAGKALKDAV 89 NPQTGEEIKI A+K+PAFKAGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.7 bits (74), Expect = 0.006 Identities = 15/86 (17%), Positives = 35/86 (40%), Gaps = 6/86 (6%) Query: 286 AEATVVRSYVDWMTSVPWSQRSKIKRDLAKAQEVLDTDHYGLEKVKDRILEYLAVQSRVR 345 A+ V + DW+ + W + ++++ L D+ +++ + V Sbjct: 527 ADMNRVHPFRDWVKAQQWDEVPRLEKWLVHVLGKTPDDYKPRRLRYLQLVGKYILMGHVA 586 Query: 346 QLKGP------ILCLVGPPGVGKTSL 365 ++ P + L G G+GK++L Sbjct: 587 RVMEPGCKFDYSVVLEGTGGIGKSTL 612
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.017 Identities = 14/70 (20%), Positives = 28/70 (40%), Gaps = 13/70 (18%) Query: 64 KLPTPHELRAHLDDYVIGQDRAKKVLSVAVYNHYKRLRNSSPKDGVELGKSNILLIGPTG 123 + P+ E + ++G+ A +Y RL + +++ G +G Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAA----MQEIYRVLARLMQT---------DLTLMITGESG 170 Query: 124 SGKTLLAETL 133 +GK L+A L Sbjct: 171 TGKELVARAL 180
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 39.1 bits (91), Expect = 6e-05 Identities = 37/148 (25%), Positives = 58/148 (39%), Gaps = 47/148 (31%) Query: 14 NAGKSTLFNAL---TGANQQVG---------NW------SGVTVEKKTGHFTLNGADVYL 55 +AGK+TL +L +GA ++G + G+T++ F V + Sbjct: 13 DAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWENTKVNI 72 Query: 56 TDLPGIYDLLPAGNSCDCSLDEQIAQQYLAEQRVDGIINLVDA-------TNIERHLYLT 108 D PG D +A+ Y + +DG I L+ A T I L Sbjct: 73 IDTPGHMDF--------------LAEVYRSLSVLDGAILLISAKDGVQAQTRI-----LF 113 Query: 109 AQLRELSIPMVVVLNKIDAAIKRGIRVD 136 LR++ IP + +NKID GI + Sbjct: 114 HALRKMGIPTIFFINKIDQN---GIDLS 138
>INTIMIN#Intimin signature. Length = 939 Score = 35.0 bits (80), Expect = 0.001 Identities = 23/114 (20%), Positives = 40/114 (35%), Gaps = 13/114 (11%) Query: 325 PSISSASMDANGTVTVAVTLSNPSTGTV--------YSDSADKLKFISDLRVYAN----W 372 S S+ D NG V +T + P V A +++F + L + Sbjct: 705 LSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIV 764 Query: 373 GTSFDYSTRSARSIRLPESTPVSGNNGTYTYTISGLTVPAGTEADHGGLAIQGR 426 GT + + SG NG YT+ + A +A G + ++ + Sbjct: 765 GTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSAN-PAIASVDASSGQVTLKEK 817 Score = 33.1 bits (75), Expect = 0.004 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 5/81 (6%) Query: 325 PSISSASMDANGTVTVAVTLSNPSTGTVYSDSADKLKFISDLRVYANWGTSFDYSTRSAR 384 S +SA+ + +G TV + P V SA + S L AN D + S Sbjct: 607 LSANSANTNGSGKATVTLKSDKPGQVVV---SAKTAEMTSALN--ANAVIFVDQTKASIT 661 Query: 385 SIRLPESTPVSGNNGTYTYTI 405 I+ ++T V+ TYT+ Sbjct: 662 EIKADKTTAVANGQDAITYTV 682
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 142 bits (359), Expect = 3e-40 Identities = 71/210 (33%), Positives = 97/210 (46%), Gaps = 24/210 (11%) Query: 126 AGMKVCIIDSGLDSSNPDFNWNNITG----DSDPGTGNWFQNGGPHGTHVAGTIGAADNN 181 G+KV ++D+G D+ +PD I G D D G F++ HGTHVAGTI A +N Sbjct: 41 RGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENE 100 Query: 182 IGVVGMAPGVPMHIVKVFNASGWGYSSDLAYAANKCSNAGAKIISMSLGGGAANNTEKNA 241 GVVG+AP + I+KV N G G + IISMSLGG A Sbjct: 101 NGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGGPEDVPELHEA 160 Query: 242 FDAFTAAGGLVVAAAGNDGNSVRS-----YPAGYPSVMMIGANDANNNIADFSQYPSCVS 296 A+ LV+ AAGN+G+ YP Y V+ +GA + + + ++FS Sbjct: 161 VKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNS----- 215 Query: 297 GRGKKAVNDDGICVEVTAGGVDTLSTYPAG 326 V++ A G D LST P G Sbjct: 216 ----------NNEVDLVAPGEDILSTVPGG 235 Score = 53.3 bits (128), Expect = 8e-10 Identities = 19/70 (27%), Positives = 27/70 (38%), Gaps = 7/70 (10%) Query: 447 YGFMSGTSMATPAVSGMAALVWSN-----HSQCTGTQIRKALKATAMDAGTVGKDNYFGY 501 Y SGTSMATP V+G AL+ T ++ L + G G Sbjct: 237 YATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLG--NSPKMEGN 294 Query: 502 GIVNAKAADA 511 G++ A + Sbjct: 295 GLLYLTAVEE 304
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 39.5 bits (92), Expect = 1e-05 Identities = 44/166 (26%), Positives = 78/166 (46%), Gaps = 23/166 (13%) Query: 186 GVILTMTMVMFT----SAAIVREREQGNMEFLITTPVRPLELMLGKI----TPYVLVGFV 237 G++ T M T AA R Q E ++ T +R +++LG++ T L G Sbjct: 72 GMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAG 131 Query: 238 QLAIILTAGH-----LLFAVPIRGGLDSIALAAMLFICASLTLGLVISTIAKTQLQSMQM 292 + G+ LL+A+P+ IAL + F +LG+V++ +A + + Sbjct: 132 IGVVAAALGYTQWLSLLYALPV------IALTGLAFA----SLGMVVTALAPSYDYFIFY 181 Query: 293 TVFILLPSILLSGFMFPYEAMPVAAQWIAEALPATHFMRMSRAIVL 338 ++ P + LSG +FP + +P+ Q A LP +H + + R I+L Sbjct: 182 QTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIML 227
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 57.9 bits (140), Expect = 2e-11 Identities = 35/180 (19%), Positives = 59/180 (32%), Gaps = 11/180 (6%) Query: 17 PSSRGWGKLLASLLGAALLLQLTACGDESPRVLGTV--ERDRLTLTAPVGELINRINVVE 74 R + L A +L + + G + + ++ I V E Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKE 114 Query: 75 GQQVQAGEVLLELDSTAAQARLGQRQAELKQA-------QAKLEEAVTGARSEDIDKARA 127 G+ V+ G+VLL+L + A+A + Q+ L QA Q E Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEP 174 Query: 128 ALDGANASVKEARQNFERTQ--QLFKTKVLSQADLDAARAARDTSLAKQAEAEQSLRLLQ 185 + + + Q K + +LD RA R T LA+ E R+ + Sbjct: 175 YFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEK 234 Score = 49.8 bits (119), Expect = 8e-09 Identities = 27/231 (11%), Positives = 75/231 (32%), Gaps = 24/231 (10%) Query: 84 LLELDSTAAQARLGQRQAELKQAQAKLEEAVTGARSEDIDKARAALDGANASVKEARQNF 143 + E + + + ++ + + + + E + R+E A ++ + + Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAE-RLTVLARINRYENLSRVEKSRL 237 Query: 144 ERTQQLFKTKVLS--------------QADLDAARAARDTSLAKQAEAEQSLRLLQNGTR 189 + L + ++ +L ++ + ++ A++ +L+ + Sbjct: 238 DDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFK 297 Query: 190 SEQLEQARAAVEAAMAGVAQEQKALKDLSLVAAK-PA---VVDTLPWRVGDRVAAGSQLI 245 +E L++ R + + K + + P V G V L+ Sbjct: 298 NEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLM 357 Query: 246 GLLAIEHPY-VRVYLPATWLDRVKAGNQVKILVDG----RTQPIAGTVRNI 291 ++ + V + + + G I V+ R + G V+NI Sbjct: 358 VIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNI 408
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.7 bits (178), Expect = 9e-18 Identities = 24/151 (15%), Positives = 55/151 (36%), Gaps = 6/151 (3%) Query: 31 SDARQRLITAAVSLFSERSYPTVSTREIARVAEVDAALIRYYFGSKAGLFEQMVRETLEP 90 + RQ ++ A+ LFS++ + S EIA+ A V I ++F K+ LF ++ + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 91 VITRLREVSTAQAPNN---VGDLMQTYYRVMAPNPGLPRLIVRVLQESDGTEAYRIMLSV 147 + E + + +++ L+ + + + ++ Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 148 FEQMLSLSRQWLEASF---VSAGILKEGLDP 175 + S +E + + A +L L Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMT 160
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 258 bits (659), Expect = 2e-91 Identities = 112/171 (65%), Positives = 145/171 (84%) Query: 1 MKKLLLLISVLVLSGCLGMPRNVEPVKDFQLERYLGKWYEIARLDHSFERGLTQVTAEYS 60 M+ + L++ ++L+GCLGMP +V+PV DF+L YLGKWYE+ARLDHSFERGL+QVTAEY Sbjct: 1 MRAIFLILCSVLLNGCLGMPESVKPVSDFELNNYLGKWYEVARLDHSFERGLSQVTAEYR 60 Query: 61 LKADGGVKVINRGYSADTQQWKEAEGKAYFVNGDEEAYLKVSFFGPFYGSYVVFGLDQQD 120 ++ DGG+ V+NRGYS + +WKEAEGKAYFVNG + YLKVSFFGPFYGSYVVF LD+++ Sbjct: 61 VRNDGGISVLNRGYSEEKGEWKEAEGKAYFVNGSTDGYLKVSFFGPFYGSYVVFELDREN 120 Query: 121 YQYAFISGPDTDYLWLLARTPTVSPEVMKQFVEMASARGFDTNSLIYVEQK 171 Y YAF+SGP+T+YLWLL+RTPTV ++ +F+EM+ RGFDTN LIYV+Q+ Sbjct: 121 YSYAFVSGPNTEYLWLLSRTPTVERGILDKFIEMSKERGFDTNRLIYVQQQ 171
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 26.8 bits (59), Expect = 0.032 Identities = 5/42 (11%), Positives = 16/42 (38%) Query: 75 NAEDVKQLTRNHLAYVEEQISKLQNLRSQLQQMVSECQGGEQ 116 ++ +K + + V I++ L + +C+ + Sbjct: 293 KSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDI 334
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 107 bits (267), Expect = 5e-30 Identities = 74/263 (28%), Positives = 126/263 (47%), Gaps = 22/263 (8%) Query: 3 LKDKVVVITGGAGGLGLAMAHNFAQAGAKLALIDVDQEKLERACADLGS-ATEVQGYALD 61 ++ K+ ITG A G+G A+A A GA +A +D + EKLE+ + L + A + + D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 62 ITDEEDVVAGFAYILEDFGKINVLVNNAGILRDGMLIKAKDGKVTDRMSFDQFQSVINVN 121 + D + A I + G I++LVN AG+LR G+ +S +++++ +VN Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGL---------IHSLSDEEWEATFSVN 116 Query: 122 LTGTFLCGREAAAAMIESGQAGVIVNISSLAKAGNVGQSNYAASKAGVAAMSVGWAKELA 181 TG F R + M++ ++ S+ A + YA+SKA + ELA Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 182 RYNIRSAAVAPGVIATEMTAAMKPE----------ALERLEKLVPVGRLGQAEEIASTVR 231 YNIR V+PG T+M ++ + +LE + +P+ +L + +IA V Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVL 236 Query: 232 FIIEND--YVNGRVFEVDGGIRL 252 F++ ++ VDGG L Sbjct: 237 FLVSGQAGHITMHNLCVDGGATL 259
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 27.4 bits (60), Expect = 0.039 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 91 AKVAELLGDLQKVMEQEVSFDQVASLLQKGADAAAYAKSLIEQQGVEQAMQSLKQMALAS 150 +KV + DL+ ++ + +V + A + AK+ + VEQA+ LK + Sbjct: 758 SKVTQAKSDLENSVKDVIINQKVTDKVDNLNQAVSVAKATGDFSRVEQALADLKN--FSK 815 Query: 151 EQFAQQ 156 EQ AQQ Sbjct: 816 EQLAQQ 821
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 31.9 bits (72), Expect = 0.028 Identities = 13/71 (18%), Positives = 28/71 (39%), Gaps = 1/71 (1%) Query: 1149 VQVPIQTAPVAVAPVAVTAAKPVVPAQAPVVQALVTEPKATIAPVSEPQVPQPQVQQPQV 1208 +++P P++V V +P Q P + EP+ P + P +++P+ Sbjct: 36 IELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVV-IEKPKP 94 Query: 1209 TQSQVAQPQVQ 1219 +P + Sbjct: 95 KPKPKPKPVKK 105
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 367 bits (944), Expect = e-125 Identities = 138/374 (36%), Positives = 197/374 (52%), Gaps = 35/374 (9%) Query: 103 KPIDMSLLCETLADFAQHLVANTSTRIRPFASELDQYGLLVGSSLPMHRLYRTIRRVSAA 162 KP D+ L +A R + LVG S M +YR + R+ Sbjct: 104 KPFDL----TELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQT 159 Query: 163 ESNVLIIGESGAGKELVANTIHLASPRVNKPYIAINCGALSPELVDSELFGHVKGSFTGA 222 + ++I GESG GKELVA +H R N P++AIN A+ +L++SELFGH KG+FTGA Sbjct: 160 DLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGA 219 Query: 223 NRDHQGVFEQAEGGTLFLDEVTEMPLEHQVKLLRVLENNEYRPVGSPKVLKANVRIVAAT 282 G FEQAEGGTLFLDE+ +MP++ Q +LLRVL+ EY VG ++++VRIVAAT Sbjct: 220 QTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAAT 279 Query: 283 NRDPLVAIEQGQLREDLYFRLAHFPIQVPPLRERGEDIVGLSKHFLAYRNAAEKQSKAFS 342 N+D +I QG REDLY+RL P+++PPLR+R EDI L +HF+ K F Sbjct: 280 NKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFD 339 Query: 343 PSSLEAIAAHTWPGNVRELKHAIERAYILADHE-ITPEHLQ-----------LTPSLEKE 390 +LE + AH WPGNVREL++ + R L + IT E ++ + + + Sbjct: 340 QEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARS 399 Query: 391 TTAEENVVIPQGMR-------------------LEELEKIAIYQALETSLGNKTDTAEQL 431 + + + + MR L E+E I AL + GN+ A+ L Sbjct: 400 GSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLL 459 Query: 432 GISVKTLYNKLSKY 445 G++ TL K+ + Sbjct: 460 GLNRNTLRKKIREL 473
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 56.5 bits (136), Expect = 5e-11 Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 16/192 (8%) Query: 1 MKKVILTASVFAISALPVLADESPSVYGRLDLSVTHSELSSTVYSGTSGVKVGESGTYLE 60 MKK ++ ++ALPV A ++YG + V S V+ +G+ + Sbjct: 1 MKKSLIA---LTLAALPVAAMADVTLYGAIKAGVQTYRSVEHTDGKVSKVE---TGSEIA 54 Query: 61 NNSSNIGVKGKSAISDGINVVYKMEFGVNNTSNRANDSSKVFSARNTYLGVETAYGTLLV 120 + S IG KG+ + +G+ V+++E S ++ + + +++G++ +GT+ Sbjct: 55 DFGSKIGFKGQEDLGNGLKAVWQLE---QGASVAGTNTG--WGNKQSFVGLKGGFGTIRA 109 Query: 121 GRNDTVFKTAEGKVDIFGTTNADINQL-VSGQTRSAD---GVWYYSPKLFGLMDINATYL 176 G ++ K V+ + + N L +SG + V Y SP+ G + Y Sbjct: 110 GSLNSPLKNTGANVNAWESGKFTGNVLEISGMAQREHRYLSVRYDSPEFAGFSG-SVQYA 168 Query: 177 LQDNYGADNELY 188 +DN G++ E Y Sbjct: 169 PKDNSGSNGESY 180
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 35.2 bits (81), Expect = 5e-04 Identities = 23/115 (20%), Positives = 48/115 (41%), Gaps = 7/115 (6%) Query: 75 AFFFTYAIGKFSNGFLADYANIGRFMSVSLMLSSITCMAMGMGVAGLFFVILWGMNGWFQ 134 AF T++IG G L+D I R + ++++ + +G + +I M + Q Sbjct: 57 AFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLI---MARFIQ 113 Query: 135 SVGSAP----SCVSIFQWYSPKQRGSVYSVWGGSRNIGEAISWILTASLVSFFGW 185 G+A V + ++ + RG + + G +GE + + + + W Sbjct: 114 GAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW 168
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 30.4 bits (68), Expect = 0.009 Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 2/48 (4%) Query: 247 YFFVSPKRPELAAAILAGLENMISDGSFDEMFNRELKIDKLYRDAQFE 294 Y+F SP++ I +N IS F+E+ +E DKL++ F+ Sbjct: 133 YYFESPEKFAFNKEIRTENQNEISLEKFNEL--KETIQDKLFKQDGFK 178
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 29.7 bits (66), Expect = 0.028 Identities = 13/38 (34%), Positives = 16/38 (42%) Query: 369 DVLTPHYNQVTTYVWERVVDFIKLHYCISDRTDSDFWL 406 DV P VT Y F +L Y + + DFWL Sbjct: 123 DVSFPQSYTVTRYQPRTESSFYRLEYWVGNSNGDDFWL 160
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 36.4 bits (84), Expect = 1e-05 Identities = 15/45 (33%), Positives = 26/45 (57%) Query: 3 NKLLGFTLVELMVTIAVAAILLTIGVPSLISVYEGVRVNNNIAKI 47 +K GFTL+E+MV I + +L ++ VP+L+ E ++ I Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDI 49
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 55.7 bits (134), Expect = 1e-12 Identities = 21/64 (32%), Positives = 41/64 (64%) Query: 2 KKNRLQGFTLIEVMIAVVIVGILASIAYPSYIDYVVKSGRSEGVAAVMKVANLQEQYYLD 61 ++ +GFTL+E+M+ +VI+G+LAS+ P+ + K+ + + V+ ++ + N + Y LD Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLD 62 Query: 62 NRSY 65 N Y Sbjct: 63 NHHY 66
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.0 bits (65), Expect = 0.020 Identities = 10/36 (27%), Positives = 16/36 (44%), Gaps = 2/36 (5%) Query: 24 RPDFLAYSQELIQVCQRLTPSDIATLMKVSDNIAGL 59 ++E + + + LTPSD A L K + G Sbjct: 147 TGSLATIAEETVIIAEDLTPSDTAQLNK--QFVKGF 180
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 149 bits (377), Expect = 6e-44 Identities = 89/378 (23%), Positives = 145/378 (38%), Gaps = 58/378 (15%) Query: 7 MKNTLK--VVLLTSMLPLAASASQELTPWYVGAGLGVNNYEHIATDNGD----DNPYAWD 60 MK T V L +A +A ++ T WY GA LG + Y N + +N Sbjct: 1 MKKTAIAIAVALAGFATVAQAAPKDNT-WYTGAKLGWSQYHDTGFINNNGPTHENQLGAG 59 Query: 61 IFAGYMFNDYFGAEIGYRDLGSADWTYAGIGNDADVKGATLGLVGVWPLGNRWSLSAEAG 120 F GY N Y G E+GY LG + + +G L +P+ + + G Sbjct: 60 AFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLG 119 Query: 121 AMYYTLENNQRVGSVSTSYSENDFAPYFGAGVGYNFTDNLKLQAKYRRYENLDDNAGANA 180 M + +V + +P F GV Y T + + +Y+ N+ G Sbjct: 120 GMVW---RADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNI----GDAH 172 Query: 181 IVPVNADSNYWGLELSYRFGSPAAPVAAAVVAATPVDSDNDGVYDDKDQCPATPATHKVD 240 + D+ L +SYRFG A A VVA P PA K Sbjct: 173 TIGTRPDNGMLSLGVSYRFGQGEA---APVVAPAPA--------------PAPEVQTKHF 215 Query: 241 SVGCTIYENVKKQEDVGSIQFANDSAVVKKEYYKDIERLANYL--NKNPEFTVEIAGHAS 298 ++ + F + A +K E +++L + L + +V + G+ Sbjct: 216 TLKSDVL-------------FNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTD 262 Query: 299 NVGKPDYNMTLSDKRADAVAKILVEKYGISQSRVTSNGYGITKPLVAGDS---------- 348 +G YN LS++RA +V L+ K GI ++++ G G + P V G++ Sbjct: 263 RIGSDAYNQGLSERRAQSVVDYLISK-GIPADKISARGMGESNP-VTGNTCDNVKQRAAL 320 Query: 349 KEAHAANRRIEAIVTTTE 366 + A +RR+E V + Sbjct: 321 IDCLAPDRRVEIEVKGIK 338
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.045 Identities = 15/60 (25%), Positives = 29/60 (48%), Gaps = 6/60 (10%) Query: 274 RAPAVQ-VSTDAKAALQPDAPKGVLLLGVQGSGKSLAAKAV---AGVWQRPLLRLDMGAL 329 R+ A+Q + +Q D +++ G G+GK L A+A+ P + ++M A+ Sbjct: 142 RSAAMQEIYRVLARLMQTDLT--LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAI 199
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 31.3 bits (71), Expect = 0.005 Identities = 10/28 (35%), Positives = 13/28 (46%), Gaps = 2/28 (7%) Query: 17 GCGELGKEVAIELQRLGVEVIGVD--RY 42 G L K V LQ+ G V+G +Y Sbjct: 62 GWATLDKAVGGILQQQGWPVVGWSSLKY 89
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 33.4 bits (76), Expect = 0.002 Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 12/108 (11%) Query: 348 GMIWFRLPLEGDKRVWPLSTLIAVAQQQPLAPH-IELEILSQANSESAQHEAPGSS---L 403 MI++R+ L + V + A A+QQP+ + L +S +++ +A S Sbjct: 31 AMIFWRIGLPDNAPVSSVQITPAQARQQPVTLNDFTLFGVSPEKNKAGALDASQMSNLPP 90 Query: 404 FQLVLVNKGNLAGKLPSQLSLAAQACSGY-------DAQNGYQAKLTQ 444 L L G +AG S+ S+A + + GY AK+ Sbjct: 91 STLNLSLTGVMAGDDDSR-SIAIISKDNEQFSRGVNEEVPGYNAKIVS 137
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 28.7 bits (64), Expect = 0.050 Identities = 17/68 (25%), Positives = 33/68 (48%), Gaps = 6/68 (8%) Query: 103 ENSELSEAQLALVNSLRDAQSLAEAEQIAAQLKESLAPALTWYSLGAMAFDAKEYDKASD 162 E ++ E QLA+ + L+ ++A +I++ E L YSL + + +Y+ A Sbjct: 4 ETTDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQL------YSLAFNQYQSGKYEDAHK 57 Query: 163 YFKKVIAL 170 F+ + L Sbjct: 58 VFQALCVL 65
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 38.1 bits (88), Expect = 9e-05 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Query: 635 IDSVPVNFLS-TLDTTGGNSGSPTLNGRAELVGLLFDGVYESIIGDWAYDDNINRSIQ 691 I + + L TTGGNSGSP N + E++G+ + GV G ++N+ ++ Sbjct: 218 ITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLK 275 Score = 30.4 bits (68), Expect = 0.025 Identities = 9/53 (16%), Positives = 15/53 (28%), Gaps = 9/53 (16%) Query: 43 DAKSISKLTEFPMNAVISLG--------GCTASFVSPKGLVVTNHHCAYGSIQ 87 D I+ T V + + V K ++TN H + Sbjct: 75 DRHQITDTTNGHYAPVTYIQVEAPTGTFIASG-VVVGKDTLLTNKHVVDATHG 126
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 34.6 bits (79), Expect = 5e-04 Identities = 15/33 (45%), Positives = 19/33 (57%) Query: 126 PQPQPQPQPQPQPQPQPQPQPQNSITEPAQAQA 158 P P+P PQP PQP PQPQP+ +P + Sbjct: 573 PAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRE 605 Score = 34.3 bits (78), Expect = 6e-04 Identities = 13/34 (38%), Positives = 16/34 (47%) Query: 123 GTTPQPQPQPQPQPQPQPQPQPQPQNSITEPAQA 156 P+P PQP PQP PQPQP+ + Sbjct: 572 PPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRE 605 Score = 33.9 bits (77), Expect = 0.001 Identities = 16/35 (45%), Positives = 17/35 (48%) Query: 121 LQGTTPQPQPQPQPQPQPQPQPQPQPQNSITEPAQ 155 L G P P+P PQP PQP PQPQ P Sbjct: 566 LVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQP 600 Score = 30.8 bits (69), Expect = 0.008 Identities = 18/34 (52%), Positives = 18/34 (52%), Gaps = 1/34 (2%) Query: 126 PQPQPQPQPQPQPQP-QPQPQPQNSITEPAQAQA 158 PQP PQP PQPQP P PQP A A A Sbjct: 579 PQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANA 612
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 28.3 bits (63), Expect = 0.049 Identities = 14/59 (23%), Positives = 27/59 (45%), Gaps = 1/59 (1%) Query: 140 THSQLLTRSTFTYLDSYRNPKEKGTLSCFDDVLAALLTESFERHYALGKVDFKPLNVIQ 198 H L L + + P ++ + + A LLT+SF R+++ +DF ++Q Sbjct: 406 KHFHLFCHYVEQILRNIQPPLVVVFVA-SNFINAHLLTDSFPRYFSDKSIDFHSYYLLQ 463
>SECA#SecA protein signature. Length = 901 Score = 49.5 bits (118), Expect = 3e-08 Identities = 17/28 (60%), Positives = 21/28 (75%) Query: 517 LQLGKPKIGRNQTCNCGSGRKYKQCCGK 544 Q G+ K+GRN C CGSG+KYKQC G+ Sbjct: 872 AQTGERKVGRNDPCPCGSGKKYKQCHGR 899
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 2e-20 Identities = 28/134 (20%), Positives = 60/134 (44%) Query: 23 ILLVEDEQDLAQMIMVNLTALNFRVFHAASLHQANALLQAKRIDLVLLDRMLPDGDGLLL 82 IL+ +D+ + ++ L+ + V ++ + A DLV+ D ++PD + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 83 CQQLRNDGQQMPVMLLTARDGEADTVLGLESGADDYMTKPFSVLELRARTKALLRRHLSA 142 +++ +PV++++A++ + E GA DY+ KPF + EL L Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 143 TPTRQLIEFEGLRI 156 + +G+ + Sbjct: 126 PSKLEDDSQDGMPL 139
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 27.6 bits (61), Expect = 0.046 Identities = 6/16 (37%), Positives = 6/16 (37%) Query: 27 PPPEPPAPPPVVMKSF 42 P P P V K F Sbjct: 200 VAPAPAPAPEVQTKHF 215
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 2e-14 Identities = 41/167 (24%), Positives = 68/167 (40%), Gaps = 8/167 (4%) Query: 1 MSQIKVAIADDHPLFRTALTQAVLKNVNTADVLEAENFQELITLVENNPDIELIFLDLHM 60 M+ + +ADD RT L QA L DV N L + +L+ D+ M Sbjct: 1 MTGATILVADDDAAIRTVLNQA-LSRAG-YDVRITSNAATLWRWIAAGD-GDLVVTDVVM 57 Query: 61 PGNEGFTGLTLLQNHFPDIAVIMVSSDDQPEIIRKAINFGASAFIPKSASLTQISTAIAT 120 P F L ++ PD+ V+++S+ + KA GA ++PK LT++ I Sbjct: 58 PDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117 Query: 121 VLEGEVWLPEHTDINVDQQ-----TAAEHQRLAKQLAQLTPQQYTVL 162 L P + + +A Q + + LA+L T++ Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLM 164
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 39.0 bits (91), Expect = 9e-05 Identities = 13/71 (18%), Positives = 29/71 (40%), Gaps = 2/71 (2%) Query: 1048 ISVLVIDNDELMLKAISSLLLGWGCHVLTARDKTSAEQQLVQQVLPKLIIADYHLDDDQN 1107 ++LV D+D + ++ L G V + + + + L++ D + D+ N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI-AAGDGDLVVTDVVMPDE-N 61 Query: 1108 GVDLVQSLLTH 1118 DL+ + Sbjct: 62 AFDLLPRIKKA 72
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.024 Identities = 26/107 (24%), Positives = 40/107 (37%), Gaps = 4/107 (3%) Query: 252 GIVGTIAGILYSRKQPLRLPIIRLSGLLIFLTVLGLSFGSAPWLQTLCAI-VLGFCIFLP 310 I G I GIL R+ PL + I ++ L + + W T+ + VLG F Sbjct: 307 IIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTK 366 Query: 311 VTALVSIPHELPKMTSQKITVIFSLFWSISYLISTLVLWLFGKLVDI 357 + L Q+ SL S+L + + G L+ I Sbjct: 367 TVISTIVSSSL---KQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 29.6 bits (66), Expect = 0.044 Identities = 23/101 (22%), Positives = 42/101 (41%), Gaps = 7/101 (6%) Query: 400 VSALSAPVELTVRVGPEPANAAPALSNIQVSVSGQCASVTGSVVDANQNLASVTVGFSSG 459 ++A + PV + + A A + V V+ S++ A + G +G Sbjct: 21 IAATAMPVNAATTINADSAINANTNAKYDVDVT---PSISAIAAVAKSDTMPAIPGSLTG 77 Query: 460 QQVSASINGTQYSAQGCNLPGGANLATVIAMDSTQLSSQDS 500 +SAS NG Y+A NLP + AT+ ++ + + Sbjct: 78 S-ISASYNGKSYTA---NLPKDSGNATITDSNNNTVKPAEL 114
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 118 bits (297), Expect = 4e-34 Identities = 76/259 (29%), Positives = 121/259 (46%), Gaps = 6/259 (2%) Query: 33 GLKGKVGLITGSTSGIGLATAHVLAEQGCHLILHGLMPEAEGQRLAAEFAEQYHIHTFFS 92 G++GK+ ITG+ GIG A A LA QG H+ PE + +++ AE H F Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF-- 62 Query: 93 NADLRDPESIHAFMDAGVKALGSIDILVNNAGIQHTENVAHFPIDKWNDIIAINLSSAFH 152 AD+RD +I + +G IDILVN AG+ + ++W ++N + F+ Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 153 TIQQAVPAMAEKRWGRIINIASVHGLVASVNKAAYCAAKHGIVGLTKVVAIECAEQGITV 212 + M ++R G I+ + S V + AAY ++K V TK + +E AE I Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 213 NAICPGWVDTPLINK-QIEAIASNKGLSYDEAKYQLVTAKQPLPEMLDPRQIGEFVLFLC 271 N + PG +T + + + + + ++ PL ++ P I + VLFL Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGI---PLKKLAKPSDIADAVLFLV 239 Query: 272 SSAARGITGASLAMDGAWT 290 S A IT +L +DG T Sbjct: 240 SGQAGHITMHNLCVDGGAT 258
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.9 bits (75), Expect = 0.002 Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 17/145 (11%) Query: 30 RTVIRSLILGLLCSGHVLLEGLPGTAKTRSVKAL------ANALAISFGRIQFTPDLLPS 83 + + R L + +++ G GT K +AL N ++ DL+ S Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIES 206 Query: 84 DVTGTE--VLHEAEGKSTLRFQP---GPVFNQIVLADEINRAPAKVQAALLEAMAEGTIT 138 ++ G E A+ +ST RF+ G +F DEI P Q LL + +G T Sbjct: 207 ELFGHEKGAFTGAQTRSTGRFEQAEGGTLF-----LDEIGDMPMDAQTRLLRVLQQGEYT 261 Query: 139 -VAGQTHVLPELFMVLATQNPIEQE 162 V G+T + ++ +V AT ++Q Sbjct: 262 TVGGRTPIRSDVRIVAATNKDLKQS 286
>INTIMIN#Intimin signature. Length = 939 Score = 31.6 bits (71), Expect = 0.027 Identities = 41/175 (23%), Positives = 67/175 (38%), Gaps = 18/175 (10%) Query: 1038 YDPNGQFNDLVKGETANEVFSYTITDEIGAT--STTEVTISVVGINAAP-VAVADTAVTT 1094 YD + N+++ ++ S I +I T ST ++ + V + D+A+ + Sbjct: 435 YDLVQRNNNIILEYKKQDILSLNIPHDINGTERSTQKIQLIVKSKYGLDRIVWDDSALRS 494 Query: 1095 KSGSIQIDLLANDTD------------ADGDTLTITAIDVGSLKGKVTNNNDGTVTYSPN 1142 + G IQ + D ++ +T A D G +NN T+T N Sbjct: 495 QGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDR---NGNSSNNVLLTITVLSN 551 Query: 1143 GQFGHLYQGQSATETFTYTISDGDAEMTASVTVTINGEGQAPVEPEKEGSSGGSL 1197 GQ T T +DG +T + TV NG QA V SG ++ Sbjct: 552 GQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAV 606
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 61.0 bits (148), Expect = 2e-12 Identities = 30/220 (13%), Positives = 72/220 (32%), Gaps = 25/220 (11%) Query: 80 FELAVSQAKLALEQVRQDNAELDASLLAAKAEVNASSTTAQQKRREAKRLDALYATHGVS 139 + S + Q + + A L A +N ++ ++ +L ++ Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA 250 Query: 140 -------QQQRDQADSDAAAAEANLSAASARLEKLKVSRGLYGED------------NLR 180 + + +A ++ ++ L + + K L + Sbjct: 251 KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDN 310 Query: 181 MRQARNALEQAELNLSYTQIHADQDGVVTNLQL-EVGSFASVGQPLLALV--SDKLDIIA 237 + L + E + I A V L++ G + + L+ +V D L++ A Sbjct: 311 IGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTA 370 Query: 238 DFREKTLRGVNASYPALIAFDGEPGRLY---RAQVSSVDA 274 + K + +N A+I + P Y +V +++ Sbjct: 371 LVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINL 410 Score = 60.6 bits (147), Expect = 2e-12 Identities = 30/197 (15%), Positives = 65/197 (32%), Gaps = 11/197 (5%) Query: 1 MTPDQQFARLVKIAMLGFVAV-FGYFMFADAMMPLTPQAMATRVVT------KVTPQISG 53 TP + RLV ++GF+ + F + + A A +T ++ P + Sbjct: 50 ETPVSRRPRLVAYFIMGFLVIAFILSVLG----QVEIVATANGKLTHSGRSKEIKPIENS 105 Query: 54 KIQTINVKNNQVVAKGDLLFQVDPAPFELAVSQAKLALEQVRQDNAELDASLLAAKAEVN 113 ++ I VK + V KGD+L ++ E + + +L Q R + + + Sbjct: 106 IVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKL 165 Query: 114 ASSTTAQQKRREAKRLDALYATHGVSQQQRDQADSDAAAAEANLSAASARLEKLKVSRGL 173 + + + + + ++Q + E NL A + Sbjct: 166 PELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINR 225 Query: 174 YGEDNLRMRQARNALEQ 190 Y + + + Sbjct: 226 YENLSRVEKSRLDDFSS 242
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 48.0 bits (114), Expect = 1e-09 Identities = 18/59 (30%), Positives = 33/59 (55%) Query: 1 MSRLHTSKGFTLIELVVVIIILGILAVVAAPRFINLSQDAHNARAKAAFAAFTSGVKLY 59 M +GFTL+E++VVI+I+G+LA + P + + A +A + A + + +Y Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMY 59
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.014 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 3/36 (8%) Query: 49 TPKNILMIGPTGVGKTEIAR---RLAKLANAPFIKV 81 T +++ G +G GK +AR K N PF+ + Sbjct: 159 TDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 27.5 bits (60), Expect = 0.036 Identities = 15/45 (33%), Positives = 21/45 (46%) Query: 146 DRDQRLAATDNPVAEARLNQLDDEFYKDLDNLDIKLESYAIQMGL 190 ++ A + AR+ QL EF LD LD + S +QM L Sbjct: 81 EQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMAL 125
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 43.1 bits (101), Expect = 3e-07 Identities = 37/195 (18%), Positives = 74/195 (37%), Gaps = 29/195 (14%) Query: 55 LEEEIKQLSQNISQLDWLINCIGMLHTEDKGPEKSLQALDGDFFLHNIQLNTLPSMMLAK 114 ++E ++ + + +D L+N G+L G SL + + +N+ ++ Sbjct: 72 IDEITARIEREMGPIDILVNVAGVLRP---GLIHSLSDEE---WEATFSVNSTGVFNASR 125 Query: 115 HFEPTLKRSASARFAVVSAKVGSISDNRLGGWYSYRASKAALNMFLKTLSIEWQRSMKHC 174 + S V + + + +Y +SKAA MF K L +E C Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMA---AYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 175 VVLALHPGTTDTPLSKP------------------FQQNVPKQKLFTPEYVAQCLVSIIA 216 +++ PG+T+T + F+ +P +KL P +A ++ +++ Sbjct: 183 NIVS--PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 217 NATPAQTGSFLAYDG 231 T L DG Sbjct: 241 GQAGHITMHNLCVDG 255
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 2e-22 Identities = 26/110 (23%), Positives = 57/110 (51%) Query: 3 RLLIIEDDQALAGVLARRLTRHGFECRLSHDASNALLVAREFCPSHILLDMKLAEANGLS 62 +L+ +DD A+ VL + L+R G++ R++ +A+ ++ D+ + + N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 LIVPLRNLLPKVIMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLLAA 112 L+ ++ P + +++++ + TA++A GA +YL KP D L+ Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114 Score = 48.3 bits (115), Expect = 3e-09 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%) Query: 116 NSQASALPEDEIDDSPLSPKRLEWEHIQQVLNANQGNVSATARQLGMHRRTLQRKLLK 173 S ALP + D L +E+ I L A +GN A LG++R TL++K+ + Sbjct: 417 ASFGDALPPSGLYDRVL--AEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>PF02370#M protein repeat Length = 168 Score = 29.7 bits (66), Expect = 0.024 Identities = 13/69 (18%), Positives = 32/69 (46%) Query: 388 DERKSKLRIQQEALKQAQKIRSAREEALKVEAETNERLEQMVQERTLELEITLRELHEVN 447 D RK + + Q + + ++ + +E + E + ++ QE+ + + ++L Sbjct: 59 DLRKREGQYQDKIEELEKERKEKQERPERREKFERQHQDKHYQEQQKKHQQEQQQLEAEK 118 Query: 448 QKLTEQSTI 456 QKL ++ I Sbjct: 119 QKLAKEKQI 127
>SECA#SecA protein signature. Length = 901 Score = 1320 bits (3417), Expect = 0.0 Identities = 662/907 (72%), Positives = 764/907 (84%), Gaps = 7/907 (0%) Query: 1 MFGKLLTKVFGSRNDRTLKGLQKVVNKINALEADYEKLTDEQLKAKTAEFRERLAAGASL 60 M KLLTKVFGSRNDRTL+ ++KVVN INA+E + EKL+DE+LK KTAEFR RL G L Sbjct: 1 MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVL 60 Query: 61 ESIMAEAFATVREASKRVFEMRHFDVQLLGGMVLDSNRIAEMRTGEGKTLTATLPAYLNA 120 E+++ EAFA VREASKRVF MRHFDVQLLGGMVL+ IAEMRTGEGKTLTATLPAYLNA Sbjct: 61 ENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNA 120 Query: 121 LTGKGVHVITVNDYLARRDAENNRPLFEFLGLTVGINVAGLGQQAKKDAYNADITYGTNN 180 LTGKGVHV+TVNDYLA+RDAENNRPLFEFLGLTVGIN+ G+ AK++AY ADITYGTNN Sbjct: 121 LTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNN 180 Query: 181 EFGFDYLRDNMAFSPQERVQRPLHYALIDEVDSILIDEARTPLIISGAAEDSSELYIKIN 240 E+GFDYLRDNMAFSP+ERVQR LHYAL+DEVDSILIDEARTPLIISG AEDSSE+Y ++N Sbjct: 181 EYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVN 240 Query: 241 TLIPNLIRQDKEDSEEYVGEGDYSIDEKAKQVHFTERGQEKVENLLIERGMLAEGDSLYS 300 +IP+LIRQ+KEDSE + GEG +S+DEK++QV+ TERG +E LL++ G++ EG+SLYS Sbjct: 241 KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS 300 Query: 301 AANISLLHHVNAALRAHTLFERDVDYIVQDGEVIIVDEHTGRTMPGRRWSEGLHQAVEAK 360 ANI L+HHV AALRAH LF RDVDYIV+DGEVIIVDEHTGRTM GRRWS+GLHQAVEAK Sbjct: 301 PANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK 360 Query: 361 EGVRIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFQHIYGLDTVVVPTNRPMVR 420 EGV+IQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEF IY LDTVVVPTNRPM+R Sbjct: 361 EGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIR 420 Query: 421 KDMADLVYLTANEKYQAIIKDIKDCRERGQPVLVGTVSIEQSELLARLMVKEKIPHQVLN 480 KD+ DLVY+T EK QAII+DIK+ +GQPVLVGT+SIE+SEL++ + K I H VLN Sbjct: 421 KDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLN 480 Query: 481 AKFHEKEAEIVAQAGRTGAVTIATNMAGRGTDIVLGGNWNMEIEALENPTAEQKAKIKAD 540 AKFH EA IVAQAG AVTIATNMAGRGTDIVLGG+W E+ ALENPTAEQ KIKAD Sbjct: 481 AKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKAD 540 Query: 541 WQERHDAVVAAGGLHILGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDSLMRIFAS 600 WQ RHDAV+ AGGLHI+GTERHESRRIDNQLRGR+GRQGDAGSSRFYLSMED+LMRIFAS Sbjct: 541 WQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFAS 600 Query: 601 DRVSGMMKKLGMEEGEAIEHPWVSRAIENAQRKVEARNFDIRKQLLEFDDVANDQRQVVY 660 DRVSGMM+KLGM+ GEAIEHPWV++AI NAQRKVE+RNFDIRKQLLE+DDVANDQR+ +Y Sbjct: 601 DRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIY 660 Query: 661 AQRNELMDAESIEDTIKNIQDDVISAVIDQYIPPQSVEELWDVPGLEQRLQQEFMLKLPI 720 +QRNEL+D + +TI +I++DV A ID YIPPQS+EE+WD+PGL++RL+ +F L LPI Sbjct: 661 SQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPI 720 Query: 721 QEWLDKEDDLHEETLRERIITSWSDAYKAKEEMVGAPVLRQFEKAVMLQTLDGLWKEHLA 780 EWLDKE +LHEETLRERI+ + Y+ KEE+VGA ++R FEK VMLQTLD LWKEHLA Sbjct: 721 AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLA 780 Query: 781 AMDHLRQGIHLRGYAQKNPKQEYKRESFELFQQLLSTLKHDVISVLSKVQVQAQSDVEEM 840 AMD+LRQGIHLRGYAQK+PKQEYKRESF +F +L +LK++VIS LSKVQV+ +VEE+ Sbjct: 781 AMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEEL 840 Query: 841 EARRREEDAKIQRDYQHAAAEALVGGDDGSDEMMAHTPMIRDGDKVGRNDPCPCGSGRKY 900 E +RR E A + D A KVGRNDPCPCGSG+KY Sbjct: 841 EQQRRMEAE-------RLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKY 893 Query: 901 KQCHGKL 907 KQCHG+L Sbjct: 894 KQCHGRL 900
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 68.6 bits (168), Expect = 6e-15 Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 20/221 (9%) Query: 150 SGMRMEAKVHIVTC----ANDMAKNITK-SVERCGLKVDDLVFSGIASADAVLTFDEKDL 204 S M ++ C A + + + S + G + L+ +A+A + Sbjct: 100 SNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEAT 159 Query: 205 GVCIVDIGGGTTDIAVYTNGALRHCAVVPVAGNQVTNDIAKIFR------TPSSHAEQIK 258 G +VDIGGGTT++AV + + + + V + G++ I R + AE+IK Sbjct: 160 GSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIK 219 Query: 259 VQFACARSSMVSREDSIEVPS---VGGRPSR-SMSRHTLAEVVEPRYQELFELVLKELKD 314 + A IEV G P +++ + + E ++ + V+ L+ Sbjct: 220 HEIGSAYPG--DEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQ 277 Query: 315 SGLE---DQIAAGIVLTGGTASIQGVVDIAEATFGMPVRVA 352 E D G+VLTGG A ++ + + G+PV VA Sbjct: 278 CPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVA 318
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 120 bits (303), Expect = 4e-36 Identities = 47/183 (25%), Positives = 76/183 (41%), Gaps = 22/183 (12%) Query: 34 PQPLSGQASDAPQINI-LMSERTPIPPKEN-------RKPEPPKPIPARERVTAPGESNQ 85 P + Q P + E P PPKE + PKP P ++ + Sbjct: 61 EPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKP 120 Query: 86 LVDFNTQTFTPEMPSQTTLFTQSAMTAE--------ALPVVQVSPRYPIDAAQNGKEGYV 137 + F P++ T T +A T++ + + P+YP A EG V Sbjct: 121 VESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQV 180 Query: 138 VVGFDITADGSVSNVRVLDANPKRVFDKAALSAVQNWKYKPKFDSGKAVPQLNQQVQLDF 197 V FD+T DG V NV++L A P +F++ +A++ W+Y+P V V + F Sbjct: 181 KVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIV------VNILF 234 Query: 198 KLD 200 K++ Sbjct: 235 KIN 237
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 71.2 bits (174), Expect = 6e-15 Identities = 41/263 (15%), Positives = 75/263 (28%), Gaps = 11/263 (4%) Query: 17 DEVVEQTPVSTPSQTEQAEALAKQHAEEARLAAEKAAAEQALADKLAAEKAEAEAQRV-A 75 ++ V+ T ++TP+ + + EE +A A A +E E A+ Sbjct: 989 NQTVDTTNITTPNNIQADVPSVPSNNEE--IARVDEAPVPPPAPATPSETTETVAENSKQ 1046 Query: 76 EEQAARIAEQQAAEAAHLAAEQALAEQL----AAEQAQAERVAAEQAAKAQAEAEAEALR 131 E + EQ A E E A + + + + +E E + A Sbjct: 1047 ESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATV 1106 Query: 132 IAEEQAARLAEQQAAEAAHLAAEQALAEQLAAEQAETERVAAEQAAKAQAEAEAEAEAEA 191 EE+A E+ + EQ Q + E A + E +++ Sbjct: 1107 EKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAE--PARENDPTVNIKEPQSQTNT 1164 Query: 192 EAEAE--AQRIAEEQAARLAEQQAAEVARLAAEQAQAEQLAAEQAEAERVAAEAQAEAER 249 A+ E A+ + + E E + A Q ++ R Sbjct: 1165 TADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHR 1224 Query: 250 VAAAQVQAEQPLEQQPEPQAKPA 272 + V Sbjct: 1225 RSVRSVPHNVEPATTSSNDRSTV 1247 Score = 68.6 bits (167), Expect = 4e-14 Identities = 37/210 (17%), Positives = 72/210 (34%), Gaps = 18/210 (8%) Query: 66 KAEAEAQRVAEEQAARIAEQQAAEAAHLAAEQALAEQLAAEQAQAERVAAEQAAKAQAEA 125 + E Q V QA + + E++A A E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPS----VPSNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 126 EAEALRIAEEQAARLAEQQAAEAAHLAAEQALAEQLAAEQAETERVAAEQAAKAQAEAEA 185 AE + E + EQ A E + A++A++ A Q + Sbjct: 1040 VAENSK-QESKTVEKNEQDATETT-------AQNREVAKEAKSNVKANTQTNEVAQSGSE 1091 Query: 186 EAEAEAEAEAEAQRIAEEQAARLAEQQAAEVARLAAEQAQAEQLAAEQAEAERVAAEAQA 245 E + E + +E+ A++ ++ EV ++ + Q++ +Q ++E V +A+ Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTS------QVSPKQEQSETVQPQAEP 1145 Query: 246 EAERVAAAQVQAEQPLEQQPEPQAKPAKES 275 E ++ Q +PAKE+ Sbjct: 1146 ARENDPTVNIKEPQSQTNTTADTEQPAKET 1175 Score = 59.7 bits (144), Expect = 2e-11 Identities = 41/238 (17%), Positives = 75/238 (31%), Gaps = 17/238 (7%) Query: 18 EVVEQTPVSTPSQTEQAEALAKQHAEEARLAAEKAAAEQALADKLAAEKAEAEAQRVAEE 77 E EQ T +Q + AK + + E A + K E V +E Sbjct: 1052 EKNEQDATETTAQNREVAKEAKSNVKANTQTNEVA--QSGSETKETQTTETKETATVEKE 1109 Query: 78 QAARI-AEQQAAEAAHLAAEQALAEQLAAEQAQAERVAAEQAAKAQAEAEAEALRIAEEQ 136 + A++ E+ + EQ Q QAE E +++ A+ Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTAD-- 1167 Query: 137 AARLAEQQAAEAAHLAAEQALAEQLAAEQAETERVAAEQAAKAQAEAEAEAEAEAEAEAE 196 +Q A+ EQ + E + E A + +E+ + + Sbjct: 1168 -----TEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNR 1222 Query: 197 AQRIAEEQAARLAEQQAAEVARLAAEQAQAEQLA-AEQAEAERVAAEAQAEAERVAAA 253 +R + + E A ++ L V ++A+A+A+ VA Sbjct: 1223 HRR------SVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALN 1274
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 31.3 bits (70), Expect = 0.009 Identities = 19/73 (26%), Positives = 33/73 (45%), Gaps = 7/73 (9%) Query: 344 IAAVVTYERNAWGNNTGDA--VQAKDVDAHKSGGTNSEPVATTPPPATTDAPKPATEPAA 401 + V T+ R++ GN T D + D+ + N++P+ P + A PA PA Sbjct: 289 VQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPL-----PEVSPAENPANNPAP 343 Query: 402 SVDPASLPTLSHD 414 + +P + P D Sbjct: 344 NENPGTRPNPEPD 356
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 566 bits (1460), Expect = 0.0 Identities = 232/333 (69%), Positives = 265/333 (79%), Gaps = 1/333 (0%) Query: 1 MKYLVTGAAGFIGAKVSERLCAQGHEVVGIDNLNDYYDVGLKLARLAPLEALSNFRFIKL 60 MKYLVTGAAGFIG VS+RL GH+VVGIDNLNDYYDV LK ARL L F+F K+ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQ-PGFQFHKI 59 Query: 61 DLADRDGIAALFAEQGFQRVIHLAAQAGVRYSLDNPLAYADSNLVGHLTILEGCRHHKIE 120 DLADR+G+ LFA F+RV + VRYSL+NP AYADSNL G L ILEGCRH+KI+ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 121 HLVYASSSSVYGLNQKMPFSTEDSVDHPISLYAATKKANELMSHTYSHLYQLPTTGLRFF 180 HL+YASSSSVYGLN+KMPFST+DSVDHP+SLYAATKKANELM+HTYSHLY LP TGLRFF Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 181 TVYGPWGRPDMALFKFTKAILAGDTIDVYNHGDLSRDFTYIDDIVEGIIRVQDKPPRPTP 240 TVYGPWGRPDMALFKFTKA+L G +IDVYN+G + RDFTYIDDI E IIR+QD P Sbjct: 180 TVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADT 239 Query: 241 DWRVETGTPANSSAPYRVFNIGNGSPVQLLDFITALESALGIEAKKQFLPMQPGDVHSTW 300 W VETGTPA S APYRV+NIGN SPV+L+D+I ALE ALGIEAKK LP+QPGDV T Sbjct: 240 QWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVLETS 299 Query: 301 ADTEDLFKAVGYKPQVDINTGVSRFVEWYRAFY 333 ADT+ L++ +G+ P+ + GV FV WYR FY Sbjct: 300 ADTKALYEVIGFTPETTVKDGVKNFVNWYRDFY 332
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 226 bits (578), Expect = 3e-79 Identities = 80/155 (51%), Positives = 113/155 (72%) Query: 5 AIYPGTFDPITNGHADLIERAAKLFKHVIIGIAANPSKQPRFTLEERVELVNRVTAHLDN 64 AIYPG+FDPIT GH D+IER +LF V + + NP+KQP F+++ER+E + + AHL N Sbjct: 3 AIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLPN 62 Query: 65 VEVVGFSGLLVDFAKEQRASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEEN 124 +V F GL V++A++++A ++RGLR +SDFE E Q+AN N+ L+ DLE+VFLT + E Sbjct: 63 AQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTEY 122 Query: 125 SFISSTLVKEVALHGGDVSQFVHPEVASALAAKLN 159 SF+SS+LVKEVA GG+V FV VA+AL + + Sbjct: 123 SFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFH 157
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 9e-24 Identities = 37/112 (33%), Positives = 60/112 (53%), Gaps = 1/112 (0%) Query: 4 KILVVDDEPQIHTFMRISLEAEGFEYLSATSIATALKQYQSHQPHLIVLDLGLPDGDGIE 63 ILV DD+ I T + +L G++ ++ AT + + L+V D+ +PD + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 LLHGLRQQDK-TPVLVLTARDQEEEKIRLLEAGANDYLSKPFGIRELIVRIK 114 LL +++ PVLV++A++ I+ E GA DYL KPF + ELI I Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 202 bits (514), Expect = 4e-62 Identities = 59/205 (28%), Positives = 109/205 (53%), Gaps = 13/205 (6%) Query: 351 EQLQEMTRKAEFTALQSKINPHFLFNALNAISSLIRIRPQQARELIANLADYLRYNLDKG 410 ++ M ++A+ AL+++INPHF+FNALN I +LI P +ARE++ +L++ +RY+L Sbjct: 152 WKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYS 211 Query: 411 D-ELIDIQEEVKQVRDYVAIEQARYGDKLEVVFDVDD--VHFCVPCLLLQPLVENAILHG 467 + + + +E+ V Y+ + ++ D+L+ ++ + VP +L+Q LVEN I HG Sbjct: 212 NARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHG 271 Query: 468 IQPRSAPGRVTIEVKKLDAGIRVAVRDTGYGISQEVIDGVAAGRIESSSIGLTNVHQRVK 527 I G++ ++ K + + + V +TG ES+ GL NV +R++ Sbjct: 272 IAQLPQGGKILLKGTKDNGTVTLEVENTG--------SLALKNTKESTGTGLQNVRERLQ 323 Query: 528 LLYGE--GLQLKRLNPGTEVSFYLP 550 +LYG ++L +P Sbjct: 324 MLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 3e-15 Identities = 24/132 (18%), Positives = 59/132 (44%), Gaps = 6/132 (4%) Query: 3 KAIIVEDEYLAREELE-YLVKSHSEIDIVASFEDGLEAFKYLQDHEVDVVFLDIQIPSID 61 ++ +D+ R L L ++ ++ I ++ + + D+V D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRW---IAAGDGDLVVTDVVMPDEN 61 Query: 62 GLLLAKNLHKSTHPPHVVFVTAHKEF--AVEAFELEAFDYILKPYNEPRIISLLQKIEQV 119 L + K+ V+ ++A F A++A E A+DY+ KP++ +I ++ + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 120 GRQAPKPQHEAA 131 ++ P + + Sbjct: 122 PKRRPSKLEDDS 133
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.3 bits (76), Expect = 0.002 Identities = 65/350 (18%), Positives = 127/350 (36%), Gaps = 42/350 (12%) Query: 43 PVSQVAFVFGLL----SLSLAVASSMAGKLQERFGVRNVTLGAGVLLGLGFLLTAQASNL 98 + V +G+L +L + + G L +RFG R V L + + + + A A L Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL 96 Query: 99 MMLYLCAGILVGFADGTGY--------LMTLSNCVKWFPERKGLISALAIGAYGLGSLGF 150 +LY+ I+ G TG + + F G +SA +G G + Sbjct: 97 WVLYI-GRIVAGITGATGAVAGAYIADITDGDERARHF----GFMSA----CFGFGMVAG 147 Query: 151 KYINMLLLENTGLETTFQLWGLIAMALVLCGGMLMKDA------PAQSAASQQAESRDFT 204 + L+ F + L G L+ ++ P + A S F Sbjct: 148 PVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLAS--FR 204 Query: 205 LAEAMSKPQYWMLALMFLSACMSG----LYVIGVAKDIGEKMVDLPVLVAANAVAVIAMA 260 A M ++A+ F+ + L+VI + + +AA + + Sbjct: 205 WARGM-TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGI----LH 259 Query: 261 NLCGRLVLGILSDKIPRIRVISLAQIITLVGMVLLLFVPLNANLFFVAVACVAFSFGGTI 320 +L ++ G ++ ++ R + L I G +LL F + F + +A G + Sbjct: 260 SLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFA-TRGWMAFPIMVLLAS-GGIGM 317 Query: 321 TVYPSLVSDFFGLNNLTKNYGVIYLGFGIGSIIGS-IVASLFGGFIATFN 369 +++S + G + + SI+G + +++ I T+N Sbjct: 318 PALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWN 367
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 182 bits (463), Expect = 3e-58 Identities = 72/295 (24%), Positives = 137/295 (46%), Gaps = 33/295 (11%) Query: 8 IAKAAGIPHKPLSQIVFWFGFILSLLLAAQITWKLVPTTSSPTAWSPTAVTTTGKGAGQI 67 I+K + + +I+F+ +L A I W++ ++P + +V T A Q Sbjct: 3 ISKLPPLSPSVIRRILFYLLMLLFCQQLAMIFWRIGLPDNAPVS----SVQITPAQARQ- 57 Query: 68 DMAGLQQLALFGKADAKSDKPKVEVVETVTDAPKTSLSIQLTGVVASTADQKGLAVIESS 127 L LFG + K+ ++ +++ P ++L++ LTGV+A D + +A+I Sbjct: 58 QPVTLNDFTLFGVSPEKNKAGALDA-SQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKD 116 Query: 128 GSQETYSLGDKIKGTSASLKEVYADRIIITNAGRYETLMLDGLVYTSQSPANQQLQKAKS 187 Q + + +++ G +A + + DR+++ GRYE L L + Sbjct: 117 NEQFSRGVNEEVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVPG------- 169 Query: 188 EKAEVVSRVDQRKNTEISQELAESRSELLADPSKITDYIAISPVRQGENVVGYRLNPGKD 247 A+V ++ QR + ++DY++ SP+ + GYRLNPG Sbjct: 170 --AQVNEQLQQR------------------ASTTMSDYVSFSPIMNDNKLQGYRLNPGPK 209 Query: 248 VNLFKQAGFKPNDLAKSINGYDLTVMSQALEMMSQLPELTEVSIMVEREGQLVEI 302 + F + G + ND+A ++NG DL QA + M ++ ++ ++ VER+GQ +I Sbjct: 210 SDSFYRVGLQDNDMAVALNGLDLRDAEQAKKAMERMADVHNFTLTVERDGQRQDI 264
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 598 bits (1542), Expect = 0.0 Identities = 326/678 (48%), Positives = 444/678 (65%), Gaps = 31/678 (4%) Query: 6 IRRKLIAGVVAGATMLTSQFVWSEQYAANFKGTDIQEFINIVGKNLNKTIIVDPTIRGKI 65 IR + ++ A + +E+++A+FKGTDIQEFIN V KNLNKT+I+DP++RG I Sbjct: 7 IRSFSLTLLIFAALLFRP--AAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTI 64 Query: 66 NVRSYDLLNDEQYYQFFLNVLQVYGYAIVEMENNVIKVIKDKDAKTAAIRVANDNDPGLG 125 VRSYD+LN+EQYYQFFL+VL VYG+A++ M N V+KV++ KDAKTAA+ VA+D PG+G Sbjct: 65 TVRSYDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIG 124 Query: 126 DEMVTRIVALYNTEAKQLAPLLRQLNDNAGGGNVVNYDPSNVLMLSGRAAVVNKLVEIVR 185 DE+VTR+V L N A+ LAPLLRQLNDNAG G+VV+Y+PSNVL+++GRAAV+ +L+ IV Sbjct: 125 DEVVTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVE 184 Query: 186 RVDKQGDTSVQVVPLEYASAGEMVRIIDTLYRATANQAQLPGQAPKVVADERINAVVVSG 245 RVD GD SV VPL +ASA ++V+++ L + T+ A VVADER NAV+VSG Sbjct: 185 RVDNAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSG 244 Query: 246 DEKSRQRVVELIHRLDAEQASTGNTKVRYLRYAKAEDLVEVLTGFAQKLEGEKDPSAQAG 305 + SRQR++ +I +LD +QA+ GNTKV YL+YAKA DLVEVLTG + ++ EK + Sbjct: 245 EPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVA 304 Query: 306 GKRRNEINIMAHTDTNALVISAEPDQMRTIESVINQLDIRRAQVLVEAIIVEVAEGDNVG 365 +N I I AH TNAL+++A PD M +E VI QLDIRR QVLVEAII EV + D + Sbjct: 305 ALDKN-IIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLN 363 Query: 366 FGVQWAAKAGGGTQFNNLGPTIGEIGAGIWQAQGEDGTTVCTENGTCTENPDSRGDVTLL 425 G+QWA K G TQF N G I AG Q + + + L Sbjct: 364 LGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVS------------------SSL 405 Query: 426 AQALGKVNGMAWGVAMGDFGALIQAVSADTNSNVLATPSITTLDNQEASFIVGDEVPILT 485 A AL NG+A G G++ L+ A+S+ T +++LATPSI TLDN EA+F VG EVP+LT Sbjct: 406 ASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLT 465 Query: 486 GSTASSNNSNPFQTVERKEVGVKLKVVPQINEGNAVKLAIEQEVSGVNG-----NTGVDI 540 GS +++ N F TVERK VG+KLKV PQINEG++V L IEQEVS V ++ + Sbjct: 466 GSQ-TTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGA 524 Query: 541 SFATRRLTTTVMADSGQIVVLGGLINEEVQESVQKVPFLGDIPVLGHLFKSSSSKKTKKN 600 +F TR + V+ SG+ VV+GGL+++ V ++ KVP LGDIPV+G LF+S+S K +K+N Sbjct: 525 TFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRN 584 Query: 601 LMIFIKPTIIRDGVTMEGIAGRKYNYFRALQLEQ--QERGVNLMPNTQVPILEEWNQSEY 658 LM+FI+PT+IRD + +Y F Q +Q +E ++ + I Q Sbjct: 585 LMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYP--RQDTA 642 Query: 659 LPPEVNDILDRYKEGKGL 676 +V+ +D + G L Sbjct: 643 AFRQVSAAIDAFNLGGNL 660
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 504 bits (1299), Expect = 0.0 Identities = 228/407 (56%), Positives = 305/407 (74%), Gaps = 1/407 (0%) Query: 1 MPAFEYKALDAKGKQLKGVIEADTARHARSQLRDQRMMPLEILPVTEKEAKAKGTGFS-P 59 M + Y+ALDA+GK+ +G EAD+AR AR LR++ ++PL + + K+ TG S Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 60 FKRGISVAELALITRQIATLVAAGLPIEECLKAVGQQCEKARLASMIMAVRSRVVEGYSL 119 K +S ++LAL+TRQ+ATLVAA +P+EE L AV +Q EK L+ ++ AVRS+V+EG+SL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 120 ADSLAEFPHIFDDLYRAMVASGEKSGHLEVVLNRLADYTERRQQLKSKLQQAMIYPIMLT 179 AD++ FP F+ LY AMVA+GE SGHL+ VLNRLADYTE+RQQ++S++QQAMIYP +LT Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 180 IVAIGVVSVLLAAVVPKVVGQFEHMGAELPATTRFLIAASDFVQSYGLLVVLIIGILLVV 239 +VAI VVS+LL+ VVPKVV QF HM LP +TR L+ SD V+++G ++L + + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 FQRLLKSPIFKMKYHTFLLKMPVVGRVSKGLNTARFARTLSILSASSVPLLDGMRIASEV 299 F+ +L+ ++ +H LL +P++GR+++GLNTAR+ARTLSIL+AS+VPLL MRI+ +V Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 300 LQNVRVRAAVDDATARVREGTSLSTALTNTKLFPAMMLYMIASGEKSGQLEDMLERAADN 359 + N R + AT VREG SL AL T LFP MM +MIASGE+SG+L+ MLERAADN Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 360 QDREFESNVTLALGVFEPALVVSMAGVVLFIVMAILQPILALNNLIS 406 QDREF S +TLALG+FEP LVVSMA VVLFIV+AILQPIL LN L+S Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 230 bits (588), Expect = 2e-81 Identities = 98/144 (68%), Positives = 118/144 (81%) Query: 1 MQMNKKHKGFTLLEVMVVIVILGILASMVVPNLMGNKDKADQQKAVSDIVALENALDMYK 60 M+ K +GFTLLE+MVVIVI+G+LAS+VVPNLMGNK+KAD+QKAVSDIVALENALDMYK Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 61 LDNGIYPTTEQGLEALVQKPTISPEPRNYRDEGYVKRLPQDPWRNNYLLLSPGENSKLDI 120 LDN YPTT QGLE+LV+ PT+ P NY EGY+KRLP DPW N+Y+L++PGE+ D+ Sbjct: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 121 FSAGPDGQPGTEDDIGNWNLQNFQ 144 SAGPDG+ GTEDDI NW L + Sbjct: 121 LSAGPDGEMGTEDDITNWGLSKKK 144
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 61.5 bits (149), Expect = 2e-14 Identities = 35/154 (22%), Positives = 56/154 (36%), Gaps = 39/154 (25%) Query: 1 MGLTAAAVTMSIGNSGPQQALEKTAQQFIAATELVLDETVLSGQFIGIVVEKTSYQFVYY 60 MG++A V ++ S A + T +F A V + +GQF G+ V +QF+ Sbjct: 18 MGVSAGMVLLAFPASRDDSAAQ-TLARFEAQLRFVQQRGLQTGQFFGVSVHPDRWQFLVL 76 Query: 61 KDG---------------KWNPLEKDRILSEKQMEPGVVINLVLDGLPLVQEDEQDESWF 105 + +W PL R+ + + G L Q E+W Sbjct: 77 EARDGADPAPADDGWSGYRWLPLRAGRVATSGS----------IAGGKLNLAFAQGEAW- 125 Query: 106 DEPLIEPSAEDKKKHPEPQILLFPSGEMSAFELS 139 P +L+FP GEM+ F L+ Sbjct: 126 ------------TPGDNPDVLIFPGGEMTPFRLT 147
>PilS_PF08805#PilS N terminal Length = 185 Score = 30.7 bits (69), Expect = 0.001 Identities = 11/32 (34%), Positives = 17/32 (53%) Query: 5 KGMTLLEVIVALAVFAIAAVSITKSLGEQMAN 36 KG TL+EV++ + V + A S K +N Sbjct: 26 KGATLMEVLLVVGVIVVLAASAYKLYSMVQSN 57
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 35.6 bits (82), Expect = 6e-05 Identities = 15/41 (36%), Positives = 28/41 (68%), Gaps = 3/41 (7%) Query: 3 LKQTNAQKGFTLLEMLIAIAIFAMLGLAANAVLSTVLTNDE 43 ++ T+ Q+GFTLLE+++ I I +G+ A+ V+ ++ N E Sbjct: 1 MRATDKQRGFTLLEIMVVIVI---IGVLASLVVPNLMGNKE 38
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 93.2 bits (231), Expect = 8e-25 Identities = 71/257 (27%), Positives = 116/257 (45%), Gaps = 16/257 (6%) Query: 6 IALITGASRGLGKNAVLTLAAQGVDIILTYQSNAAAAAEVVAEIEWHGRKAVALPLDVGN 65 IA ITGA++G+G+ TLA+QG I N +VV+ ++ R A A P DV + Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 66 SQSFSDFSQRVKTALEQTWQRDSFNYLVNNAGIGIHVPMAETSMEQFDTLMNIHVKGPFF 125 S + + + R++ + + LVN AG+ + S E+++ +++ G F Sbjct: 69 SAAIDEITARIEREMGP------IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 126 LTQALLPLLAD--NGSIINVSTGLTRFAVPGFGAYATMKGAVETMTKYWAKELGPRGIRV 183 ++++ + D +GSI+ V + AYA+ K A TK EL IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 184 NVLAPGAIETDF-------GGGAVRDNRQMNEFLAQQTALGRVGLPEDIGGAISVLLSPA 236 N+++PG+ ETD GA + + E L ++ P DI A+ L+S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 237 AAWINAQRIEASGGMFL 253 A I + GG L Sbjct: 243 AGHITMHNLCVDGGATL 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 343 bits (882), Expect = e-114 Identities = 121/375 (32%), Positives = 200/375 (53%), Gaps = 17/375 (4%) Query: 259 FHRDSALHVQTQALALTQTKSTRTLQDKPSNQLGVRFRDPLLERAWQQANKVITKQIPLL 318 F + + +ALA + + ++ D + R ++ ++ +++ + L+ Sbjct: 106 FDLTELIGIIGRALAEPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLM 164 Query: 319 VLGETGVGKEQFVKKLHAQSARRAQPLVAVNCAALPAELVESELFGYQAGAFTGANRTGF 378 + GE+G GKE + LH RR P VA+N AA+P +L+ESELFG++ GAFTGA Sbjct: 165 ITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRS- 223 Query: 379 IGKIRQAHGGFLFLDEIGEMPLAAQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDL 438 G+ QA GG LFLDEIG+MP+ AQ+RLLRVLQ+ E VG + D++I+AAT+ DL Sbjct: 224 TGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDL 283 Query: 439 ESLVAQGLFRQDLFYRLNGLQVRLPALRERQ-DIERIIH---KLHRRHRSSAQTLCTELL 494 + + QGLFR+DL+YRLN + +RLP LR+R DI ++ + + + E L Sbjct: 284 KQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEAL 343 Query: 495 AQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHLPDYLAQKLMNLAFEPQTLTEVVD 554 + + WPGN+REL+NL++ + + V+ + + L ++ + E Sbjct: 344 ELMKAHPWPGNVRELENLVRRLTALYPQD-VITREIIENELRSEIPDSPIEKAAARSGSL 402 Query: 555 AETTAHPHELSESSSTTIDSLHGTINLN----------VLQAYRACEGNVSQCAKRLGIS 604 + + A + + ++ D+L + + +L A A GN + A LG++ Sbjct: 403 SISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLN 462 Query: 605 RNALYRKLKQLGVKD 619 RN L +K+++LGV Sbjct: 463 RNTLRKKIRELGVSV 477
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 4e-05 Identities = 25/121 (20%), Positives = 52/121 (42%), Gaps = 12/121 (9%) Query: 274 IAYEAEQLEKLIAELLELSRVKLSTNETKVRLGLAESLSQVLDDAEFEADQQGKKIT--I 331 I + + +++ L EL R L + + + LA+ L+ V + + Q ++ Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQ-VSLADELTVVDSYLQLASIQFEDRLQFEN 244 Query: 332 DIDEAIELGHYPKSLSRAIENLLRNAIRYA------QSDIHLRASQTNGQVQITIKDDGP 385 I+ AI P L ++ L+ N I++ I L+ ++ NG V + +++ G Sbjct: 245 QINPAIMDVQVPPML---VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS 301 Query: 386 G 386 Sbjct: 302 L 302
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.8 bits (241), Expect = 2e-25 Identities = 46/163 (28%), Positives = 77/163 (47%), Gaps = 3/163 (1%) Query: 2 SRILLIDDDLGLSELLGQLLELEGFKLTLAYDGKQGLELALAGDYDLILLDVMLPKLNGF 61 + IL+ DDD + +L Q L G+ + + + AGD DL++ DV++P N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EVLRALRQH-KQTPVLMLTARGDEIDRVVGLEIGADDYLPKPFNDRELIARIRAIIRRSH 120 ++L +++ PVL+++A+ + + E GA DYLPKPF+ ELI I + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 LTAQEIHATPAQEFGDLRLDPSRQEAYCNEQLIILTGTEFTLL 163 ++ + + QE Y L L T+ TL+ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIY--RVLARLMQTDLTLM 164
>PF01206#SirA family protein Length = 76 Score = 27.0 bits (60), Expect = 0.008 Identities = 6/35 (17%), Positives = 14/35 (40%) Query: 90 PLLMWRSRVTCAQSGKVVIVECLDERKRRSLIRWC 124 P+L + + +G+V+ V D + + Sbjct: 18 PILKAKKTLATMNAGEVLYVMATDPGSVKDFESFS 52
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 69.2 bits (169), Expect = 2e-16 Identities = 50/202 (24%), Positives = 69/202 (34%), Gaps = 28/202 (13%) Query: 1 MKKLSLVAVTLLSALVAGQASAATDNTGFYVGGAL-------NRVTVDAFDDSETGTGFG 53 MKK +A+ + A A A AA + +Y G L + E G G Sbjct: 1 MKKT-AIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAG 59 Query: 54 VYGGYNFNEWFGLEANFF----ATADLGDSDVDISAGALTFTPKFTLQINDMFSAYAKVG 109 +GGY N + G E + + A + T K I D Y ++G Sbjct: 60 AFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLG 119 Query: 110 VA----SMAVNVDGLGFDEDFTGFGWTYGVGVNAAVTEHLNVRLSYDITT--GDLDADHS 163 NV G D TG + GV A+T + RL Y T GD Sbjct: 120 GMVWRADTKSNVYGKNHD---TGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTI-- 174 Query: 164 YLNMKDIDTDMKQLAIGVHYQF 185 D L++GV Y+F Sbjct: 175 -----GTRPDNGMLSLGVSYRF 191
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 557 bits (1438), Expect = 0.0 Identities = 198/474 (41%), Positives = 294/474 (62%), Gaps = 12/474 (2%) Query: 7 VWILDDDSSIRWVLEKALQGAKLSTASFAAAESLWQALEISQPRVIVSDIRMPGTDGLTL 66 + + DDD++IR VL +AL A + A +LW+ + ++V+D+ MP + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 67 LERLQIHYPHIPVIIMTAHSDLDSAVSAYQAGAFEYLPKPFDIDEAISLVERALTHATEQ 126 L R++ P +PV++M+A + +A+ A + GA++YLPKPFD+ E I ++ RAL + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE--PK 123 Query: 127 SPSPAPQETQVKTPEIIGEAPAMQEVFRAIGRLSRSSISVLINGQSGTGKELVAGALHKH 186 ++ ++G + AMQE++R + RL ++ ++++I G+SGTGKELVA ALH + Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 187 SPRKDKPFIALNMAAIPKDLIESELFGHEKGAFTGAANVRQGRFEQANGGTLFLDEIGDM 246 R++ PF+A+NMAAIP+DLIESELFGHEKGAFTGA GRFEQA GGTLFLDEIGDM Sbjct: 184 GKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 247 PLDVQTRLLRVLADGQFYRVGGHSAVQVDVRIIAATHQDLEQLVLKGGFREDLFHRLNVI 306 P+D QTRLLRVL G++ VGG + ++ DVRI+AAT++DL+Q + +G FREDL++RLNV+ Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVV 303 Query: 307 RVHLPPLSQRREDIPQLATHFLASAAKEIGVEAKILTKETAAKLSQLPWPGNVRQLENTC 366 + LPPL R EDIP L HF+ A KE G++ K +E + PWPGNVR+LEN Sbjct: 304 PLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVRELENLV 362 Query: 367 RWLTVMASGQEILPQDLPPELLKEPASINPMAKGSQDWQSALTEWIDQKLSE-------- 418 R LT + I + + EL E ++ ++++ +++ + + Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDA 422 Query: 419 -GNSDLLTEVQPAFERILLETALRHTQGHKQEAAKRLGWGRNTLTRKLKELSMD 471 S L V E L+ AL T+G++ +AA LG RNTL +K++EL + Sbjct: 423 LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 40.6 bits (95), Expect = 5e-06 Identities = 35/187 (18%), Positives = 72/187 (38%), Gaps = 33/187 (17%) Query: 167 LIIEQADRLRSLVDRL-------LGPQRPTQHSLHNIHQVVQKVYKLVEMALPTNIQLKR 219 LI+E + R ++ L L Q SL + VV +L + +Q + Sbjct: 185 LILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFEN 244 Query: 220 DYDPSIPDIEMDPDQMQQAVLNILQNAVQALEHTGGEILIRTRTQHQVTIGSQRHKLVLT 279 +P+I D+++ P +Q V N +++ + L GG+IL++ + +T Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQ-GGKILLKGTKDNGT----------VT 293 Query: 280 LSIIDNGPGIPPELMDTLFYPMVTSREQGSGLGLSIAHNIARLHSG---RIDCVSSPGHT 336 L + + G + + ++ +G GL ++ G +I G Sbjct: 294 LEVENTGSL------------ALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV 341 Query: 337 EFIISLP 343 ++ +P Sbjct: 342 NAMVLIP 348
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.9 bits (142), Expect = 5e-13 Identities = 25/68 (36%), Positives = 32/68 (47%) Query: 1 MKTETQSTRQHILDVGYSLIVKQGFSCLGLAQLLKAAQVPKGSFYHYFKSKEQFGEALLT 60 K E Q TRQHILDV L +QG S L ++ KAA V +G+ Y +FK K + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 GYFEQYQA 68 Sbjct: 65 LSESNIGE 72
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 355 bits (913), Expect = e-121 Identities = 137/479 (28%), Positives = 228/479 (47%), Gaps = 48/479 (10%) Query: 18 LLVLDPEQSLPE-CSEELKQAAWNCLKAVSAAEALVLLQKYDLRVAIAFIN--DTNQVLL 74 +LV D + ++ ++ L +A ++ +AA + D + + + D N L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 75 ANEIAIIQTEYPSLHWIAVTD-STLEQHCSWLSAANFIDYYHRPFDWGRFADTLGHAWGM 133 + I+ P L + ++ +T + DY +PFD +G A Sbjct: 66 ---LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAY-DYLPKPFDLTELIGIIGRALAE 121 Query: 134 AQLTVAKKGKSAPTEALTTIKGDHPLLQQLRQRLHKFSLSDDTVLLSGETGSGKGLCAKT 193 + +K + + G +Q++ + L + +D T++++GE+G+GK L A+ Sbjct: 122 PKRRPSKLEDDSQDGM--PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 194 LHSLSKRRDGPFITVNCGALPIGLIHSALFGHEKGAFTDADKRYIGHLEQANGGTLFLDE 253 LH KRR+GPF+ +N A+P LI S LFGHEKGAFT A R G EQA GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 254 IADLPLDLQVNLLHVLDDKQIMRIGGNVPIKVDCRLLFASHQDLEVAIDEGRFREDLYHR 313 I D+P+D Q LL VL + +GG PI+ D R++ A+++DL+ +I++G FREDLY+R Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 314 INVLRLHVPSLRQYSDEVMLLAEDFLQE-NTDSNVQFHFSDDARCAMKHYNWPGNVRELR 372 +NV+ L +P LR ++++ L F+Q+ + F +A MK + WPGNVREL Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELE 359 Query: 373 NRIRRAMVLSDDSKITAQLLGLDQLPSRAGQDLARCRV---------------------- 410 N +RR L IT +++ + + + Sbjct: 360 NLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 411 ---------------EHEAEVLLKAISDHKHNISAAARSLNISRATFYRLLKKCQIKMP 454 E E ++L A++ + N AA L ++R T + +++ + + Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVY 478
>PF06580#Sensor histidine kinase Length = 349 Score = 40.6 bits (95), Expect = 2e-05 Identities = 21/107 (19%), Positives = 37/107 (34%), Gaps = 22/107 (20%) Query: 608 LVIRNLISNAIKH---HDKGEGVIKVICETSNHHYWFSVIDDGPGISSRFHGKVFQMFQT 664 ++++ L+ N IKH G I + N V + G Sbjct: 258 MLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS---------------- 301 Query: 665 LRPRDEVEGSGLGLSLVKKTVESLGGK---IQLESEGRGCCFRFSWP 708 L ++ E +G GL V++ ++ L G I+L + P Sbjct: 302 LALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 44.4 bits (105), Expect = 3e-08 Identities = 21/108 (19%), Positives = 41/108 (37%), Gaps = 8/108 (7%) Query: 11 TILLVDDDDVDYMAVQRAMKQLRLLNPLVRARDGLEALAILTHSDAIKGSYLILLDLNMP 70 TIL+ DDD + +A+ + + + + L++ D+ MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAA----GDGDLVVTDVVMP 58 Query: 71 RMNGFEFLEHIRANPALSSSVVFMLTTSSTDEDRMRAYSHHVAGYMVK 118 N F+ L I+ A V +++ +T ++A Y+ K Sbjct: 59 DENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK 104
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 4e-12 Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Query: 3 LLLIDDDDVDRTAIIRALRQSKLAFNVIEANCAFDGLNLALERHFDGILLDYLLPDANGL 62 +L+ DDD RT + +AL S+ ++V + A D ++ D ++PD N Sbjct: 6 ILVADDDAAIRTVLNQAL--SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 EVLIKLNSMTQEQTVVLMLSRYEDEKLAQRCIELGAQDFLLK 104 ++L ++ + VL++S A + E GA D+L K Sbjct: 64 DLLPRIKKA-RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK 104
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 33.0 bits (75), Expect = 7e-04 Identities = 35/200 (17%), Positives = 66/200 (33%), Gaps = 54/200 (27%) Query: 47 VAIQGGIDYSHDSGFYAGTWASNVDFGDDTSYELDLYAGYGGNITEDLSYDIGYLYYAYP 106 + G HD+GF +N + + GY + + +++GY + Sbjct: 30 TGAKLGWSQYHDTGFI-----NNNGPTHENQLGAGAFGGY--QVNPYVGFEMGYDWLGRM 82 Query: 107 DAEGSID-------------------------FGELHGAITWKWFELSYSHVINAGDDVA 141 +GS++ + L G + W + S+V D Sbjct: 83 PYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMV---WRADTKSNVYGKNHDTG 139 Query: 142 AEPLDNKDMSYLAATASFPLTDKLSLSLHYGYSSGDVVESWFDEDNYADYNVTLSADTSM 201 P+ A + +T +++ L Y +++ N D + T+ Sbjct: 140 VSPV-------FAGGVEYAITPEIATRLEYQWTN-----------NIGDAH-TIGTRPDN 180 Query: 202 GTVSFMVSDTDLQGDDAKVV 221 G +S VS QG+ A VV Sbjct: 181 GMLSLGVSYRFGQGEAAPVV 200
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 109 bits (275), Expect = 2e-35 Identities = 44/88 (50%), Positives = 66/88 (75%) Query: 2 NKTELIAKIAENADITKAEAARALKSFEAAITESMKNGDKISIVGFGSFETSTRAARTGR 61 NK +LIAK+AE ++TK ++A A+ + +A++ + G+K+ ++GFG+FE RAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEIQIAEATVPKFKAGKTLRDSV 89 NPQTG+EI+I + VP FKAGK L+D+V Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 6e-13 Identities = 24/107 (22%), Positives = 43/107 (40%), Gaps = 3/107 (2%) Query: 146 RVLVVDDSRMARNVIKRTIGNLGIKQITEAEDGAQAIELMRNNMFDLIITDYNMPSVDGL 205 +LV DD R V+ + + G + A + DL++TD MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 206 ALTQFIRNESQQSHVPILMVSSEANDAHLSNVSQAGVNALCDKPFEP 252 L I+ + +P+L++S++ S+ G KPF+ Sbjct: 64 DLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDL 108 Score = 47.9 bits (114), Expect = 2e-08 Identities = 29/155 (18%), Positives = 58/155 (37%), Gaps = 6/155 (3%) Query: 10 SILIVEPSETQRRIIIKRLQQEGIISIQNAASLTQARELIARHKPDLIASAMYFEDGTAT 69 +IL+ + R ++ + L + G ++ ++ IA DL+ + + D A Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 70 EFLSYLRTKSEYKDIQFMLVSSECRREQLEIFRQSGVVAILPKPFNAEHLGKALNATIDL 129 + L ++ D+ +++S++ + G LPKPF+ L + + Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 130 LSHDELDLSHFDVHDVRVLVVDDSRM--ARNVIKR 162 L D D LV + M V+ R Sbjct: 122 PKRRPSKLED-DSQDGMPLVGRSAAMQEIYRVLAR 155
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.6 bits (204), Expect = 2e-20 Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 1/131 (0%) Query: 1 MQNPHILIVEDEAVTRNTLRSIFEAEGYVVTEANDGAEMHKAMQENKINLVVMDINLPGK 60 M IL+ +D+A R L GY V ++ A + + + +LVV D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELREIN-NIGLIFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLT 119 N L +++ ++ ++ ++ ++ + I E GA DY+ KPF+ EL L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RVNSAGNEVEE 130 +++E+ Sbjct: 121 EPKRRPSKLED 131
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 30.9 bits (70), Expect = 0.009 Identities = 18/81 (22%), Positives = 27/81 (33%), Gaps = 5/81 (6%) Query: 202 DYSAALLAEALKASAVEIWTDVAGIYTTDPRLAPNAHPIAEISFNEAAEMATFGAKVLHP 261 D + LAE + A I TDV G + E+ E + G Sbjct: 216 DLAGEKLAEEVNADIFMILTDVNGAALY--YGTEKEQWLREVKVEELRKYYEEGH--FKA 271 Query: 262 ATILPAVRQQIQVFVGSSKEP 282 ++ P V I+ F+ E Sbjct: 272 GSMGPKVLAAIR-FIEWGGER 291
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.7 bits (155), Expect = 3e-14 Identities = 27/159 (16%), Positives = 62/159 (38%), Gaps = 9/159 (5%) Query: 6 SVLVVDDHPLLRKGICQLIASDPDFSLFGEVGGGLDALSAVATDEPDIVLLDLNMKGMTG 65 ++LV DD +R + Q S + + +A + D+V+ D+ M Sbjct: 5 TILVADDDAAIRTVLNQ-ALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 66 LDTLNAMRQEGVTSRIVILTVSDAKQDVIRLLRAGADGYLLKDTEPDLLLDKLKNAMLGH 125 D L +++ +++++ + I+ GA YL K + L+ + A+ Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL--- 119 Query: 126 RVISDEVEEYLYELKNAADEQEWISSLTPRELQILQQLA 164 E + +L++ + + + + +I + LA Sbjct: 120 ----AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLA 154
>PF06580#Sensor histidine kinase Length = 349 Score = 42.2 bits (99), Expect = 4e-06 Identities = 27/148 (18%), Positives = 56/148 (37%), Gaps = 19/148 (12%) Query: 405 NQLTEINEGVSTAYVQLRELL----STFRLTIKEPNLKN-AMEAMLEQLRANTDI----- 454 N L I + + RE+L R +++ N + ++ L + + + Sbjct: 177 NALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQF 236 Query: 455 --KIHLDYKLSPQWLEAKQHIHILQITREATLNAIKHANASR----VIIRCYKDDNGMVN 508 ++ + +++P ++ + ++Q E N IKH A I+ DNG V Sbjct: 237 EDRLQFENQINPAIMDVQVPPMLVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVT 293 Query: 509 ISVSDNGIGIGYLKERDQHFGIGIMHER 536 + V + G + G+ + ER Sbjct: 294 LEVENTGSLALKNTKESTGTGLQNVRER 321
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 41.0 bits (96), Expect = 2e-07 Identities = 16/31 (51%), Positives = 23/31 (74%) Query: 2 ASRTNAGFTLVELMVAIAIIGILASIALPSY 32 A+ GFTL+E+MV I IIG+LAS+ +P+ Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNL 33
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 53.7 bits (129), Expect = 3e-12 Identities = 19/64 (29%), Positives = 38/64 (59%) Query: 5 RKGFTLIELMIAVAIIGILAAIAIPSFNEYLKQGRRFDAQQYLVSSAQALERHYSRNGLY 64 ++GFTL+E+M+ + IIG+LA++ +P+ ++ + A +V+ AL+ + N Y Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHY 66 Query: 65 PASQ 68 P + Sbjct: 67 PTTN 70
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 78.3 bits (193), Expect = 9e-17 Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 5/139 (3%) Query: 1283 SILVADDNATARDIMRTTLESMGFRVDTVRSGEEAVTRCSQQEYAVALIDWKMPNLDGIE 1342 +ILVADD+A R ++ L G+ V + + + + + D MP+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1343 TAKQIKQLAKNAPRILMVSAHATQEFLSQIEAL--GLAGYISKPISASRLLDGIMNSLGR 1400 +IK+ + P ++M SA T + I+A G Y+ KP + L+ I +L Sbjct: 65 LLPRIKKARPDLPVLVM-SAQNTFM--TAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 1401 AGVLPVRRNSESIDPKLLL 1419 P + +S D L+ Sbjct: 122 PKRRPSKLEDDSQDGMPLV 140 Score = 70.6 bits (173), Expect = 3e-14 Identities = 29/130 (22%), Positives = 49/130 (37%), Gaps = 5/130 (3%) Query: 1425 RILLVEDNEMNLEVATEFLEQVGIILSIATNGQIALDKLAQQSFDLVLMDCQMPVMDGYQ 1484 IL+ +D+ V + L + G + I +N +A DLV+ D MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1485 ATQAIRKRPELAELPVIAMTANAMAGDKEMCLKAGMNDHIAKP---IEVNLLYQTLLKYL 1541 I+K +LPV+ M+A + G D++ KP E+ + L Sbjct: 65 LLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 1542 GAGVLPTEAA 1551 E Sbjct: 123 KRRPSKLEDD 132
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.3 bits (224), Expect = 4e-22 Identities = 39/159 (24%), Positives = 65/159 (40%), Gaps = 6/159 (3%) Query: 1 MDKATILVVDDTPENIDILVGILG-EDYKVKVAIDGPRALALVAKTLPDLILLDVMMPGM 59 M ATILV DD +L L Y V++ + +A DL++ DV+MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 NGYEVCKLLKQEPLTCHIPVIFVTALSEVADETQGFELGAVDYITKPVSAPVVKARVRTH 119 N +++ +K+ +PV+ ++A + + E GA DY+ KP + + Sbjct: 61 NAFDLLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 LALYDQKRLLEQQVKERTQEL--EETRF-EIIRRLGRAA 155 LA ++ + + L EI R L R Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLM 157
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 204 bits (520), Expect = 2e-61 Identities = 103/298 (34%), Positives = 140/298 (46%), Gaps = 39/298 (13%) Query: 128 WGMNNTGQNGGTVDADIDAPEAWEITTGSSDVVIGVIDTGVDYNHPDLQTNMWVNGGEIP 187 N G + I AP W T G V + V+DTG D +HPDL+ + I Sbjct: 16 EQQVNEIPRGVEM---IQAPAVWNQTRGR-GVKVAVLDTGCDADHPDLKARI------IG 65 Query: 188 GNGIDDDGNGVIDDVHGYSAVNNNGNPMDGNGHGTHVSGTIGAKGNNGVGVVGVNWDVKI 247 G DD G + D NGHGTHV+GTI A N GVVGV + + Sbjct: 66 GRNFTDDDEGDPEI------------FKDYNGHGTHVAGTIAA-TENENGVVGVAPEADL 112 Query: 248 AACQFLDADGYGSTAGAIACLDYFTDLKVNHGVDIKATNNSWGGGSFSQALKDAIEAGGE 307 + L+ G G I + Y + VDI + S GG L +A++ Sbjct: 113 LIIKVLNKQGSGQYDWIIQGIYYA----IEQKVDI--ISMSLGGPEDVPELHEAVKKAVA 166 Query: 308 AGILFVAAAGNDAVDND--ASPHYPSSYDSDVVLSIASTDRNDRMSDFSQWGLTSVDMGA 365 + IL + AAGN+ +D YP Y+ V+S+ + + + S+FS VD+ A Sbjct: 167 SQILVMCAAGNEGDGDDRTDELGYPGCYNE--VISVGAINFDRHASEFSNSN-NEVDLVA 223 Query: 366 PGTAILSTIPGGGYATYSGTSMATPHVTGAAALVWSLNP-----DLSPVEMKSLLMAS 418 PG ILST+PGG YAT+SGTSMATPHV GA AL+ L DL+ E+ + L+ Sbjct: 224 PGEDILSTVPGGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKR 281
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 29.8 bits (67), Expect = 0.007 Identities = 7/26 (26%), Positives = 14/26 (53%) Query: 34 HQGHITLVKEAAKKCDHVVVSIFVNP 59 GH+ +++ + D V V++ NP Sbjct: 13 TFGHLDIIERGCRLFDQVYVAVLRNP 38
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 31.8 bits (72), Expect = 0.001 Identities = 9/52 (17%), Positives = 17/52 (32%), Gaps = 2/52 (3%) Query: 65 AADDILRTLEAFGFEWDDEVLYQSDRT--EAYQAKLDELLAEDNAYFCQCSR 114 I + + GFE Y S E ++ L + + +C + Sbjct: 27 PYSLIKKFMLENGFEHRQYSGYTSKEPINERRVIRIVNKLTKKFTWLGECVK 78
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 27.0 bits (59), Expect = 0.031 Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 13/81 (16%) Query: 24 GEEYMNAKQLGHFKTILEAWRNQLREEVDRTLSHMQDEAANFPDPVDRAAQEEEFSLELR 83 E AKQ+ ++ L + + + S FPDP D E LR Sbjct: 88 DEALPKAKQILKLISVH---GGALEDFLRQARSL-------FPDPSDLVLVLREL---LR 134 Query: 84 ARDRERKLIKKIEKTLQKIEE 104 +D E + KK+E L+ +EE Sbjct: 135 RKDLEEIVRKKLESLLKHVEE 155
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 498 bits (1285), Expect = e-161 Identities = 210/1043 (20%), Positives = 444/1043 (42%), Gaps = 49/1043 (4%) Query: 11 FARNSVAANLLMWALLIGGLFSTVLINKEVFPSFNLNLLSITVAYPGAAPQEIEEGINIK 70 F R + A +L L++ G + + + +P+ +S++ YPGA Q +++ + Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 71 IEEAIQDINGIKKVTSVA-SEGVGAITVEVEDDYDVQTVLDEAKLRLDAI-STFPVNIEK 128 IE+ + I+ + ++S + S G IT+ + D + + +L P +++ Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 129 PQIFKIEPENNVIWV----SVYGDMSLHDMKELAKS-VRDDLTQLPAVTRAKVTGVRDYE 183 I + ++ + V S + D+ + S V+D L++L V ++ G Y Sbjct: 125 QGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-AQYA 183 Query: 184 IGIEVSEDKLREYGLTFSQVALAVQNSSIDLPGGSIRAEDG------DILLRTKGQAYTG 237 + I + D L +Y LT V ++ + + G + + + + + Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 238 DDFANIVVTTRADGSRVMLPQVATIKDDFEERLEYTRFNGKPAAIIEVTSVNDQNALDIA 297 ++F + + +DGS V L VA ++ E R NGKPAA + + NALD A Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTA 303 Query: 298 QQVKDYVEKRRATLPANAKLDTWGDLTHYLKGRLNMMMSNMFYGALLVFVILALFL-DLK 356 + +K + + + P K+ D T +++ ++ ++ +F +LVF+++ LFL +++ Sbjct: 304 KAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMR 363 Query: 357 LAFWVMMGLPVCFLGTMLIMPLEPFSMTINMLTLFAFILVLGIVVDDAIVIGESAYSE-V 415 + +PV LGT I+ F +IN LT+F +L +G++VDDAIV+ E+ + Sbjct: 364 ATLIPTIAVPVVLLGTFAILAA--FGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 416 ERHGHSIDNVIRGAQKVAMPATFGVLTTIAAFIPMLMVSGPMGIIWKSIGMVVIMCLAFS 475 E + + ++ + A FIPM G G I++ + ++ +A S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 476 LVESKFILPAHLAHM-KFRKPGE---PTGFFGRFKDRFNNRVQHFIHHSYRNFLERCIQH 531 ++ + + PA A + K GFFG F F++ V H Y N + + + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNH-----YTNSVGKILGS 536 Query: 532 RYNVVAAFIGVLILSVALVVSGKVRWVFFPDIPSDFIQVQLEMDEGSSEQNTLKVVQDIE 591 + + ++ V L + ++ F P+ +++ G++++ T KV+ + Sbjct: 537 TGRYLLIYALIVAGMVVLFL--RLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVT 594 Query: 592 EALYKMNAKMEKDNGSEVVKHSFINMSSRTSAFIFAELTKGEDREVDGET---IAAAWRE 648 + K + + V SF ++ + F L E+R D + + + Sbjct: 595 DYYLKNEKANVESVFT-VNGFSFSGQ-AQNAGMAFVSLKPWEERNGDENSAEAVIHRAKM 652 Query: 649 QLPELLSVKKLDFNAS-----GNGGGGGDISFRLTSSDLEELSAAARELKQKLATY-EGV 702 +L ++ + FN G G + L+ A +L A + + Sbjct: 653 ELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASL 712 Query: 703 YDIADNFSSGSHEIRLKI-RPEAEALGLTLSDLARQVRYGFYGYEAQRILRNKEEIKVMV 761 + N + + +L++ + +A+ALG++LSD+ + + G + K+ V Sbjct: 713 VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYV 772 Query: 762 RYPLEQRRTVGYLENMLIRTPQGKSVPFSTVAEVEKGESYASITRVDGKRAITIIANANK 821 + + R ++ + +R+ G+ VPFS + R +G ++ I Sbjct: 773 QADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGE--- 829 Query: 822 HKVEPSKVVNEIQKDFLPQLQAKYPK-IQTTLDGGSLDEQNAMVGLMQGFFFALFTIYAL 880 P + + L +K P I G S E+ + + ++ Sbjct: 830 --AAPGTSSGDAM-ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLC 886 Query: 881 MAVPLKSYSQPLIIMSVIPFGIIGALFGHLIQGLAMSVLSLCGIVALAGVVVNDSLILVD 940 +A +S+S P+ +M V+P GI+G L + V + G++ G+ +++++V+ Sbjct: 887 LAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVE 946 Query: 941 FVNRARE-QGLSIKQAAVDSGCYRFRAIILTSLTTFVGLVPIILERSLQAQIVIPMATSL 999 F E +G + +A + + R R I++TSL +G++P+ + + + + Sbjct: 947 FAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGV 1006 Query: 1000 AFGILFSTVVTLILVPLLYIILD 1022 G++ +T++ + VP+ ++++ Sbjct: 1007 MGGMVSATLLAIFFVPVFFVVIR 1029
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.1 bits (99), Expect = 3e-06 Identities = 24/121 (19%), Positives = 47/121 (38%), Gaps = 7/121 (5%) Query: 106 DYEADLMQAEATLAQATAALNEEIARGEVAKIEFKGYDKGLPPELGLRIPQLKKEQANVK 165 + E ++A L + L + + AK E++ + E+ + +L++ N+ Sbjct: 256 EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI---LDKLRQTTDNIG 312 Query: 166 YAQAALARAQRNLERTVIRAPFDGIIKARNV-DLGQYVTLGTNLGELY---DTRIAEIRL 221 LA+ + + +VIRAP ++ V G VT L + DT + Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALV 372 Query: 222 P 222 Sbjct: 373 Q 373 Score = 38.3 bits (89), Expect = 5e-05 Identities = 25/125 (20%), Positives = 53/125 (42%), Gaps = 11/125 (8%) Query: 62 GVVTPKYKTQLVTEVQGRMLSISPQFVA-GGIVKKGDQLAQIEPSDYEADLMQAEATLAQ 120 G +T +++ + ++ + + V G V+KGD L ++ EAD ++ +++L Q Sbjct: 88 GKLTHSGRSKEIKPIENSI--VKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQ 145 Query: 121 ATA------ALNEEIARGEVAKIEFKGYD--KGLPPELGLRIPQLKKEQANVKYAQAALA 172 A L+ I ++ +++ + + E LR+ L KEQ + Q Sbjct: 146 ARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQK 205 Query: 173 RAQRN 177 + Sbjct: 206 ELNLD 210
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 7e-13 Identities = 27/138 (19%), Positives = 47/138 (34%), Gaps = 5/138 (3%) Query: 785 TLLVVDDIQQNIDLLSVWLTRQGHKVITARDGEQALLRMQKADIDITLMDLQMPVMDGLT 844 T+LV DD +L+ L+R G+ V + + D D+ + D+ MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 845 AAKMRREQEAESQLPHMPIIALTASVLEQDKSAAEQAGMDGFANKPIDFALLTREIARVL 904 + P +P++ ++A A + G + KP D L I R L Sbjct: 65 L-----LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 905 QLNPPQAEAESLQPLGSQ 922 + Sbjct: 120 AEPKRRPSKLEDDSQDGM 137
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.5 bits (196), Expect = 1e-18 Identities = 31/169 (18%), Positives = 60/169 (35%), Gaps = 23/169 (13%) Query: 10 TLLLVDDEPVNLRVLKQVLHQ-DYHLIFAKSGEEALRLAQTELPSLILLDIMMPNMTGLE 68 T+L+ DD+ VL Q L + Y + + R L++ D++MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 69 VCQLLKNIPETQSIPVIFVTALNDEHDEAAGFAVGGVDYIVKPISATIVKARVKTHLSLV 128 + +K +PV+ ++A N G DY+ KP T + + L+ Sbjct: 65 LLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 129 QADELRRTR---------------LQVIQRLGRAAEYKDN-----ETGT 157 + + ++ + L R + E+GT Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGT 171
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.6 bits (74), Expect = 4e-04 Identities = 12/46 (26%), Positives = 23/46 (50%), Gaps = 2/46 (4%) Query: 12 QTGFTLIELMISLT-LGLVVMLGASQIFVSVNKAYVETQRFSQLQG 56 Q GFTL+E+M+ + +G++ L + + KA + S + Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAV-SDIVA 51
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 78.0 bits (192), Expect = 1e-17 Identities = 31/172 (18%), Positives = 82/172 (47%), Gaps = 4/172 (2%) Query: 442 VTIVEERTIGPTLGAENIQNGFAALGLGMGITLLFMALWYR-RLGWVANVALIANMVILF 500 + I ++GP + E + +L + + ++ + + + A VAL+ ++++ Sbjct: 135 LKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTV 194 Query: 501 GLLALIPGAVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFALA--IDTGFDSA 558 GL A++ L +A L+ G +++ V++F+R+++ L + ++ L ++ + Sbjct: 195 GLFAVL-QLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNET 253 Query: 559 FSTIFDANFTTMITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGIFASRALI 610 S TT++ V + G I+GF + G+ T ++ ++ ++ ++ Sbjct: 254 LSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIV 305
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 239 bits (611), Expect = 8e-80 Identities = 90/305 (29%), Positives = 154/305 (50%), Gaps = 20/305 (6%) Query: 2 KNLNLTKWRYVSSAISLFLMLASLTIIGMKGFNWGLDFTGGVVTEVQLDRRITSSELQPL 61 N + +W++ + ++ +M+AS+ + + G N+G+DF GG + I + Sbjct: 12 TNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRAA 71 Query: 62 LNAAYQQEVTVISASEP--------------------GRWVLRYADTAQSNVNIQETLAP 101 L +V + +P G N A Sbjct: 72 LEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAV 131 Query: 102 LGEVQVLNTSIVGPQVGKELAEQGGLALLVAMLCILGYLSYRFEWRLASGALFALVHDVI 161 +++ + VGP+V EL +LL A + I+ Y+ RFEW+ A GA+ ALVHDV+ Sbjct: 132 DPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVL 191 Query: 162 FVLAFFSLTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKLAIQEINNQAIV 221 + F++ Q++F+LT +AA+L I GYS+ND++++ DR+RE LI + ++++ N ++ Sbjct: 192 LTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVN 251 Query: 222 ATFSRTMVTSGTTLMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSLPEFLGLT 281 T SRT++T TTL+ + + I GG + GF AM G+ TGT+SS+ V ++ F+GL Sbjct: 252 ETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLD 311 Query: 282 PEHYK 286 K Sbjct: 312 RNKEK 316
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 0.002 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 18/82 (21%) Query: 198 VLMVGPPGTGKTLLAKAIAGESK---VPFFT-----ISGSDFVEMFVGV------GASRV 243 +++ G GTGK L+A+A+ K PF I G GA Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR 222 Query: 244 RD-MFEQAKKSAPCIIFIDEID 264 FEQA+ +F+DEI Sbjct: 223 STGRFEQAEGGT---LFLDEIG 241
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 54.2 bits (130), Expect = 2e-11 Identities = 33/160 (20%), Positives = 59/160 (36%), Gaps = 5/160 (3%) Query: 23 LAKALEVFWRKGFEGTSLTDLTQAMGINKPSLYAAFGNKEQLFLKAIELYEQLPCAFFYP 82 L AL +F ++G TSL ++ +A G+ + ++Y F +K LF + EL E Sbjct: 17 LDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELE 76 Query: 83 SLEK--ETAYQVAESMLYGAATNLVDKNHPQGCLIVQGALACSEAGQAIKETLITRRRDG 140 K V +L + V + + + + C G+ R Sbjct: 77 YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHK-CEFVGEMAVVQQAQRNLCL 135 Query: 141 E--QALCQRLQRAKDEGDLPADADPLLLSRYIGTVLQGMA 178 E + Q L+ + LPAD + + + G+ Sbjct: 136 ESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLM 175
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 45.2 bits (107), Expect = 3e-07 Identities = 23/123 (18%), Positives = 48/123 (39%), Gaps = 5/123 (4%) Query: 64 SVTLVPRVSGYIASVNFKEGALVKKGDVLFHIDASVFEAEVARLKADLASALSAE---QL 120 S + P + + + KEG V+KGDVL + A EA+ + ++ L A + Q+ Sbjct: 96 SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQI 155 Query: 121 ATNDLERARKLFAQKAVSAELLDTRESNKRQTTAAVASVKAALLR--AELDLDYTQVRAP 178 + +E + + + E + T+ + + + +L+ + RA Sbjct: 156 LSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAE 215 Query: 179 IDG 181 Sbjct: 216 RLT 218 Score = 39.4 bits (92), Expect = 2e-05 Identities = 21/102 (20%), Positives = 41/102 (40%), Gaps = 10/102 (9%) Query: 101 EAEVARLKADLASALSAEQLATNDLERARKLFAQKAVSAELLDTRESNKRQTTAAVASVK 160 E+ K+ L S A + + +LF + + +L RQTT + + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLF-KNEILDKL--------RQTTDNIGLLT 315 Query: 161 AALLRAELDLDYTQVRAPIDGRASYANV-TAGNYVSAGQSVL 201 L + E + +RAP+ + V T G V+ ++++ Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLM 357
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1035 bits (2679), Expect = 0.0 Identities = 419/1043 (40%), Positives = 640/1043 (61%), Gaps = 18/1043 (1%) Query: 2 LSQFFIKRPIFAAVLSLLFFITGAIAVWQLPITEYPEVVPPTVVVTANYPGANPKVIAET 61 ++ FFI+RPIFA VL+++ + GA+A+ QLP+ +YP + PP V V+ANYPGA+ + + +T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 62 VASPLEQEINGVEDMLYMSSQATSDGRMTLTITFAIGTDVDRAQTQVQSRVDRAMPRLPQ 121 V +EQ +NG+++++YMSS + S G +T+T+TF GTD D AQ QVQ+++ A P LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 EVQRLGIVTEKSSPDLTMVVHLLSPDNRYDMLYLSNYAALNVKDELARIKGVGAVRLFGA 181 EVQ+ GI EKSS MV +S + +S+Y A NVKD L+R+ GVG V+LFG Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 182 GEYSLRIWLDPNKVSALGMSPAEIIAAVREQNQQAAAGSLGAQPSGNA-DFQLLINVKGR 240 +Y++RIWLD + ++ ++P ++I ++ QN Q AAG LG P+ I + R Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 241 LTELSEFEDIIIKVGQNGEVIRLKDVARVELGATSYALRSLLDNKDAVAIPVFQASGSNA 300 EF + ++V +G V+RLKDVARVELG +Y + + ++ K A + + A+G+NA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 301 IQISDDVRAEMARLAKSFPEGLQYEIVYDPTVFVRGSIHAVVKTLLEAVLLVVLVVVLFL 360 + + ++A++A L FP+G++ YD T FV+ SIH VVKTL EA++LV LV+ LFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 361 QTWRASIIPLVAVPVSLVGTFAFMHLMGFSLNALSLFGLVLAIGIVVDDAIVVVENVERN 420 Q RA++IP +AVPV L+GTFA + G+S+N L++FG+VLAIG++VDDAIVVVENVER Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 421 IAS-GLSPIAATQKAMKEVTGPIVATTLVLAAVFIPTAFMSGLTGQFYKQFALTITISTF 479 + L P AT+K+M ++ G +V +VL+AVFIP AF G TG Y+QF++TI + Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 480 ISAINSLTLSPALSALLLKGHDAPKDALTRLMDKLFGGWLFTPFNRLFNRASEGYGYLVR 539 +S + +L L+PAL A LLK A G F FN F+ + Y V Sbjct: 480 LSVLVALILTPALCATLLKPVSAE--------HHENKGGFFGWFNTTFDHSVNHYTNSVG 531 Query: 540 KVIRFGGIIGLVYLGMVALTGVQFVNTPTGYVPGQDKQYLVAFAQLPDAASLERTDAVIK 599 K++ G L+Y +VA V F+ P+ ++P +D+ + QLP A+ ERT V+ Sbjct: 532 KILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLD 591 Query: 600 KMSDIALNH--PGVAHSIAFPGLSINGFTNSPNSGVVFVALDDFELRKSPELSANAIAGQ 657 +++D L + V G S +G + N+G+ FV+L +E R E SA A+ + Sbjct: 592 QVTDYYLKNEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAVIHR 649 Query: 658 LNQQFAGIQDAFIAIFPPPPVQGLGTIGGFRLQIQDRANLGYEALYQVTQQVMYKAWADP 717 + I+D F+ F P + LGT GF ++ D+A LG++AL Q Q++ A P Sbjct: 650 AKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHP 709 Query: 718 -QLAGIFSSYQVNVPQLELDIDRTKAKQQAVSLDQIFQTLQTYMGSTYVNDFNRFGRTYQ 776 L + + + Q +L++D+ KA+ VSL I QT+ T +G TYVNDF GR + Sbjct: 710 ASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKK 769 Query: 777 VNMQADEAFRQSPQQISQLKVPNVNGDMIPLGSFINVSQSAGPDRVMHYNGFTTAEINGG 836 + +QAD FR P+ + +L V + NG+M+P +F G R+ YNG + EI G Sbjct: 770 LYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGE 829 Query: 837 PAPGVSSGQAQAAIEKILAETLPIGMTYEWTELTYQQILAGNTGLLVFPLVILLVFMVLA 896 APG SSG A A +E + ++ LP G+ Y+WT ++YQ+ L+GN + + ++VF+ LA Sbjct: 830 AAPGTSSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLA 888 Query: 897 AQYESLSLPLAIILIIPMTLLSALSGVLIYGGDNNIFTQIGLIVLVGLATKNAILIVEFA 956 A YES S+P++++L++P+ ++ L ++ N+++ +GL+ +GL+ KNAILIVEFA Sbjct: 889 ALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFA 948 Query: 957 KEKQDH-GMEVMESILEAARLRLRPILMTSIAFIMGVVPMVFSTGAGAEMRQAMGVAVFA 1015 K+ + G V+E+ L A R+RLRPILMTS+AFI+GV+P+ S GAG+ + A+G+ V Sbjct: 949 KDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMG 1008 Query: 1016 GMIGVTLFGLILTPLFYYALAKR 1038 GM+ TL + P+F+ + + Sbjct: 1009 GMVSATLLAIFFVPVFFVVIRRC 1031
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.003 Identities = 21/74 (28%), Positives = 27/74 (36%), Gaps = 4/74 (5%) Query: 6 KFLAHLTTALLITALPISTVLLAGCAQSD--PNTPSPSANASPTTLYQALGDDS--GVSA 61 + LA+ TA + A S AG A P PSA A GDD Sbjct: 372 RVLAYFGTARALLADVSSPTAAAGGAGGGEPPKKRDPSAGAGTDPGGPGGGDDGEDPFGE 431 Query: 62 IVDGLLARIARDPR 75 +D +AR+ R Sbjct: 432 WLDDEVARLRLRGR 445
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 58.7 bits (142), Expect = 1e-11 Identities = 51/230 (22%), Positives = 105/230 (45%), Gaps = 15/230 (6%) Query: 7 LWLCVLLMMFPQIMETIYSPALPNIAENFAVSVTSASQTLSVYFIAFAVGVFCWGRLADI 66 +WLC+L + E + + +LP+IA +F S + + + + F++G +G+L+D Sbjct: 17 IWLCILSFFSV-LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 67 IGRRNAMLAGLVCYAIGSAFALM-ISDFTLLLLARILSAFGAA----VGSVITQTMMRDS 121 +G + +L G++ GS + S F+LL++AR + GAA + V+ + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 122 YSGEELAKVFSVMGMSLGISPIIGLLLGSLLSAYWGYQGVFVALMVSAIVLLFLSLKSLP 181 G+ + S++ M G+ P IG ++ + +W Y + + + I+ + +K L Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI--HWSY---LLLIPMITIITVPFLMKLLK 190 Query: 182 ETRPAHTQKIAIVELAIKMLTDSGIIKNTLLVASFNLMWFSYFSLAPFMF 231 + I + L GI+ L S+++ + L+ +F Sbjct: 191 KEV-RIKGHFDIKGII---LMSVGIVFFMLFTTSYSISFLIVSVLSFLIF 236
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 778 bits (2011), Expect = 0.0 Identities = 308/1032 (29%), Positives = 517/1032 (50%), Gaps = 28/1032 (2%) Query: 3 LSDVSVKRPVVAIVLSLLLCVFGLVSFTKLSVREMPDVESPVVTVSTSYSGASAAIMESQ 62 +++ ++RP+ A VL+++L + G ++ +L V + P + P V+VS +Y GA A ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 ITKTLEDELTGISGIDEITSTT-RNGSSRITVKFLLGWNLTEGVSDVRDAVARAQRRLPE 121 +T+ +E + GI + ++ST+ GS IT+ F G + V++ + A LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 DANDPVVSKDNGSGEPSVYVNLSSSVMDRTQ--LTDYAQRVLEDRFSLISGVSSISISGG 179 + +S + S + S TQ ++DY ++D S ++GV + + G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 LYKVMYVKLRPEQMAGRNVTVTDIINALRKENVETPGGQVRNDTTV------MSVRTKRL 233 Y + + L + + +T D+IN L+ +N + GQ+ + S+ + Sbjct: 181 QYAMR-IWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 YYTPKDFDYLVVRTASDGTPIYLKDVADVAVGAQNENSTFKSDGIVNLSLGVITQSDANP 293 + P++F + +R SDG+ + LKDVA V +G +N N + +G LG+ + AN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 LIVAQEVHKEVDRIQDFLPEGTSLVVDFDSTVFIDRSINEVYNTLYVTGALVVLVLYIFI 353 L A+ + ++ +Q F P+G ++ +D+T F+ SI+EV TL+ LV LV+Y+F+ Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 GQTRATLIPAVTVPVSLISAFIAANMFGYSINLLTLMALILAIGLVVDDAIVVVENIFHH 413 RATLIP + VPV L+ F FGYSIN LT+ ++LAIGL+VDDAIVVVEN+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 I-ERGEEPLLAAYKGTREVGFAVVATTAVLVMVFLPISFMEGMVGLLFTEFSVMLAVSVL 472 + E P A K ++ A+V VL VF+P++F G G ++ +FS+ + ++ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 FSSLIALTLTPVLSSKLLKANVK-----PNRFNRFVDSGFARMEKVYRVGVTQAIRFKWL 527 S L+AL LTP L + LLK F + ++ F Y V + + Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 528 APLVILACVGGSAWLMQQVPSQLAPQEDRGVLFAFVKGAEGTSYNRMTANMDIVEDRLMP 587 L+ V G L ++PS P+ED+GV ++ G + R +D V D + Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 588 LLGQGVLRSFSVQAPAFGGRAGDQTGFVIMQLEDWEHRHVTAQQALGIIS---NALKDIP 644 V F+V +F G+ G + L+ WE R+ A +I L I Sbjct: 600 NEKANVESVFTVNGFSFSGQ-AQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 645 DVMVRPM-MPGFRGQ-SSEPVQFVL---GGSDYAELFKWAQVLKEEANASP-MMEGADLD 698 D V P MP ++ F L G + L + L A P + + Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 699 YAETTPELIVTVDKERAAELGISVDEVSQTLEVMLGGRKETTYVDRGEEYDVYLRGDENS 758 E T + + VD+E+A LG+S+ +++QT+ LGG ++DRG +Y++ D Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 759 FNNVGDLSQIYMRSAKGELVTLDTLTHIEEVASAQKLSHTNKQKSITLKANISKGYTLGE 818 D+ ++Y+RSA GE+V T V + +L N S+ ++ + G + G+ Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 819 ALKFLDNKAIELLPKDISIGYTGESKDFKENQSSILIVFGLALLVAYLVLAAQFESFINP 878 A+ ++N A + LP I +TG S + + + + ++ +V +L LAA +ES+ P Sbjct: 839 AMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIP 897 Query: 879 LVVMFTVPMGVFGGFLGLLVTSQGINIYSQIGMIMLIGMVTKNGILIVEFANQLRDR-GL 937 + VM VP+G+ G L + +Q ++Y +G++ IG+ KN ILIVEFA L ++ G Sbjct: 898 VSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGK 957 Query: 938 ALDKAIIDASTRRLRPILMTAFTTLVGAVPLIFSSGAGSESRIAVGTVVFFGMAFATFVT 997 + +A + A RLRPILMT+ ++G +PL S+GAGS ++ AVG V GM AT + Sbjct: 958 GVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLA 1017 Query: 998 LFVIPAMYRLIS 1009 +F +P + +I Sbjct: 1018 IFFVPVFFVVIR 1029
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.4 bits (123), Expect = 3e-09 Identities = 21/108 (19%), Positives = 46/108 (42%), Gaps = 3/108 (2%) Query: 50 PLTQSISLIGKLA-ADRAVVIAPQVTGKIKQIAVTSNQAVKKGQLLIELDDMKAQAAVAE 108 + + GKL + R+ I P +K+I V ++V+KG +L++L + A+A + Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 109 ANAFLNDETRKLREFEKLISRNAITQTEIDAQKASVDIARARLASAQA 156 + L +L + I +I ++ K + ++ + Sbjct: 139 TQSSL--LQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEV 184
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 2e-18 Identities = 19/115 (16%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Query: 18 IRVGLVEDQQLVRQGIASLIAISQHIEVSWQAENGQEALKRLQTDAVDVLLSDIRMPVLD 77 + + +D +R + ++ + + N + + D++++D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 78 GLSLLKQLRAAQNSIPVIMLTTFDDSELFLNSLQAGANGFLLKDVSLDKLLEAIE 132 LL +++ A+ +PV++++ + + + + GA +L K L +L+ I Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 45.2 bits (107), Expect = 2e-07 Identities = 57/377 (15%), Positives = 137/377 (36%), Gaps = 84/377 (22%) Query: 45 HIALYSLFILFFLLLTTLDFPRKNLNLSRLLSTALVGSVFGLMLLS--------QHPLLP 96 + ++ L +L K ++ ++ +L+G V S + + Sbjct: 16 QGIGWGVYTLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQ 75 Query: 97 ILLVIWAS----------------LLPEFFNRRVAIAQILLAN-LGYYLILHAQTSNSVM 139 I+L + + L F N + + LA + + +++ + + Sbjct: 76 IILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVVVVTFMWSLLY 135 Query: 140 INVLIYMGFQLFAYSSSQARLSERESR------RIQEH-LNQQLIATRALLSQTSEQQER 192 + ++ + +E++ +I H + L RAL+ + + Sbjct: 136 FGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKARE 195 Query: 193 LRISRDLHDILGHQLTALSLQLELLSHQAPTELKPTVNQSKSLAKELLESIRAVVRAQRV 252 + LT+LS EL+ + L+ + + SLA EL + + ++ + Sbjct: 196 M-------------LTSLS---ELMRYS----LRYSNARQVSLADEL-TVVDSYLQLASI 234 Query: 253 NIGLDLTPPLDAIVSRLPNVSLQYESLMPLQSTELAQALLLVLQEGISNAVRHG-----K 307 + + LQ+E+ + + Q +++Q + N ++HG + Sbjct: 235 ---------------QFED-RLQFENQIN-PAIMDVQVPPMLVQTLVENGIKHGIAQLPQ 277 Query: 308 ANQLTLSMQEEQAELIICLKDNGQGI--SQSPSQGVGLSSMQERLSPFHGSARLQANQAG 365 ++ L ++ + + +++ G + S G GL +++ERL +G +A Sbjct: 278 GGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYG------TEAQ 331 Query: 366 VDSSRTQGC-SLMIRLP 381 + S QG + M+ +P Sbjct: 332 IKLSEKQGKVNAMVLIP 348
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 37.7 bits (87), Expect = 1e-05 Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 18/125 (14%) Query: 8 KTALLIIDMQQ---GLFYADAPPFNREQVLNNINLLIAKAREAGAPIWAVRHTG---PE- 60 + LLI DMQ F A A P ++ NI L + + G P+ G P+ Sbjct: 30 RAVLLIHDMQNYFVDAFTAGASPV--TELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDD 87 Query: 61 --------GSPIAAGTANWQLIESLAINPQLDNIFDKTKPSCFYQTGLAEALAHEGVSEL 112 G + +G ++I LA D + K + S F +T L E + EG +L Sbjct: 88 RALLTDFWGPGLNSGPYEEKIITELAPEDD-DLVLTKWRYSAFKRTNLLEMMRKEGRDQL 146 Query: 113 VIVGM 117 +I G+ Sbjct: 147 IITGI 151
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.5 bits (128), Expect = 4e-11 Identities = 34/170 (20%), Positives = 65/170 (38%), Gaps = 9/170 (5%) Query: 2 RNAEFDRAQVLRGAMAAFMHKGYTKTSMQDLTQATGLHPGSIYCAFSNKRGLLIAAIEQY 61 + A+ R +L A+ F +G + TS+ ++ +A G+ G+IY F +K L E Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 62 QQDRNEQFKLIFSNSRPVLGNLKTYLDNIVVECLSCDSQQA--CLLTKALNEIAEQDDEI 119 + + E L G+ + L I++ L + LL + + E E+ Sbjct: 67 ESNIGE---LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEM 123 Query: 120 QNIIS---QNLMLWQNALTAQFELAASQGMLQGELNSEQRAQYLMMGIYG 166 + + + + + ML +L + RA +M G Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTR-RAAIIMRGYIS 172
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.012 Identities = 13/39 (33%), Positives = 17/39 (43%), Gaps = 6/39 (15%) Query: 339 LFGYVENATFRGTVFTDFSLIRPGSLHKANGGVLLMDAI 377 LFG+ + A FT G +A GG L +D I Sbjct: 208 LFGHEKGA------FTGAQTRSTGRFEQAEGGTLFLDEI 240
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.3 bits (78), Expect = 0.002 Identities = 35/264 (13%), Positives = 85/264 (32%), Gaps = 35/264 (13%) Query: 393 QASVQSIEQQASKAQRIAKQNGEEAQALMQQTDQIATAIEEMSTSIRDVANHAQDGANQS 452 +V+ EQ A++ ++ +EA++ ++ Q AQ G+ Sbjct: 1048 SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEV--------------AQSGSETK 1093 Query: 453 QQVDLAAKEGQQQQTQVVQDLLKLSQQLSSSHQAVEKVSQE-SEAISKVTEVINSIAEQT 511 + KE + + + Q + QE SE + E + Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAE-----PARE 1148 Query: 512 NLLALNAAIEAARAGEQGRGFAVVADEVRTLAQRTQSSI---LEISQTIDKLQSQVKTTT 568 N +N ++ + A+ T S++ + S T++ S V+ Sbjct: 1149 NDPTVNIKEPQSQTNTTA--------DTEQPAKETSSNVEQPVTESTTVNTGNSVVENPE 1200 Query: 569 SQMAQSHQLGIASANQGEETGKQLEEITRRIGELAISSRNIASATEQQSSVAQEITHNLH 628 + + Q + S + + + + + +++ +S+VA + + Sbjct: 1201 NTTPATTQPTVNSESSNKPKNRHRRSVRSV----PHNVEPATTSSNDRSTVALCDLTSTN 1256 Query: 629 QISELANEGEHRAAETVNSANDLS 652 + L++ +N +S Sbjct: 1257 TNAVLSDARAKAQFVALNVGKAVS 1280
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 376 bits (967), Expect = e-116 Identities = 208/1050 (19%), Positives = 421/1050 (40%), Gaps = 60/1050 (5%) Query: 1 MIKAFVENGRLVSLVIALLLVAGFGAISSLPRTEDPHITNRFASVITPYPGASAERVEAL 60 M F+ ++ +L++AG AI LP + P I SV YPGA A+ V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTEVLENQLRRLEEIKLIQSTS-RPGISVIQLELKDTVKDTDPVWSR--ARDLLADARNT 117 VT+V+E + ++ + + STS G I L + TDP ++ ++ L A Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQS---GTDPDIAQVQVQNKLQLATPL 117 Query: 118 LPDGVQT---STLDDQVGYAYTAILSLVWNNSSQPRVDMLNRYAKE-LQSRLRLLSGTDF 173 LP VQ S Y A ++Q D ++ Y ++ L L+G Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQ---DDISDYVASNVKDTLSRLNGVGD 174 Query: 174 VKLYGAPEEEILVQLDGYKMSQLQLTPGTIAKILSSADSKIAAGEINN------NNFRAF 227 V+L+GA + + + LD +++ +LTP + L + +IAAG++ A Sbjct: 175 VQLFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS 233 Query: 228 VEVSGELDSQSRIRQVPLKVDTQGQIIRLGDIAHISRQPKTPADSIALVDGEQGVFVAAR 287 + + +V L+V++ G ++RL D+A + + + IA ++G+ + + Sbjct: 234 IIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENY-NVIARINGKPAAGLGIK 292 Query: 288 MLNNTRVDIWQGQVKQLVDEFNQELPANIKVQWLFEQNSYTSDRLGGLIINLLQGFVIIL 347 + +K + E P +KV + ++ + + ++ L + +++ Sbjct: 293 LATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVF 352 Query: 348 AVLLLTLG-LRNAIIVALSLPLTALFTLACMKYIGLPIHQMSVTGLVVALGIMVDNAIVI 406 V+ L L +R +I +++P+ L T A + G I+ +++ G+V+A+G++VD+AIV+ Sbjct: 353 LVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVV 412 Query: 407 VDAIAQRRQ-QGMSRLRAVSETLHHLWLPLAGSTITTILAFAPIVLMPGAAGEFVGGIAM 465 V+ + + + A +++ + L G + F P+ G+ G ++ Sbjct: 413 VENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSI 472 Query: 466 SVMFALLGSYVISHTLIAGLAGRF--SLEGKHP-------VWYQHGINVPLVSGYFQASL 516 +++ A+ S +++ L L + +H W+ + V+ Y S+ Sbjct: 473 TIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFD-HSVNHY-TNSV 530 Query: 517 RFALNRPLLSATFIGIIPLLGFYASGKMTEQFFPPSDRDMFQIELYLAPHVSLENTLNQV 576 L +I ++ F P D+ +F + L + E T + Sbjct: 531 GKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVL 590 Query: 577 QLMDKQL--HQIEGITQVDWVVGGNTPSFYYNLTQRQQGATNYAQAMVK-----ASDFER 629 + ++ + V V G + Q A +K D Sbjct: 591 DQVTDYYLKNEKANVESVFTVNGFSFSG--------QAQNAGMAFVSLKPWEERNGDENS 642 Query: 630 ANALIPELQQTLDK---AFPEAQVLVRKLEQGPPFNAPVELM-IFGPNLETLRSLGDEVR 685 A A+I + L K F + +E G EL+ G + L +++ Sbjct: 643 AEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLL 702 Query: 686 NILAATP-DVLHTRATLSAGAPKVWLQVNEDASLISGLTLTDIARQVQMATTGVIGGSVL 744 + A P ++ R + L+V+++ + G++L+DI + + A G + Sbjct: 703 GMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFI 762 Query: 745 EQTESLPIRVRLGDTSREQASRLSEIQLVTPSGTAVPLSALSHNEVQVSRGAIPRRNGQR 804 ++ + V+ R + ++ + + +G VP SA + + + R NG Sbjct: 763 DRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLP 822 Query: 805 VNTIEAYIVSGVLPAQVLNDVKDKVAGISLPAGYRIEIGGESAKRNEAIGNLLSNLILVV 864 I+ G + +++ + LPAG + G S + + + + + Sbjct: 823 SMEIQGEAAPGTSSGDAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISF 880 Query: 865 TLLLATVVLSFNSFRLTAIILLSALQSAGLGLLAVYVFGYPFGFPVIIALLGLMGLAINA 924 ++ + + S+ + ++L LLA +F ++ LL +GL+ Sbjct: 881 VVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKN 940 Query: 925 AIVILAELEDTDNARA-GDKEVIITTVSGCGRHITSTTITTVGGFIPLII---AGGGFWP 980 AI+I+ +D G E + V R I T++ + G +PL I AG G Sbjct: 941 AILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQN 1000 Query: 981 PFAIAIAGGTLLTTLLSLVWVPTMYLLLMK 1010 I + GG + TLL++ +VP ++++ + Sbjct: 1001 AVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 3e-06 Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 5/106 (4%) Query: 75 SGKLSELTVDSGARVTQGQVLAKLDTRLLDAEHQEIQASLAQTQADVDLATSTLNRNLEL 134 + + E+ V G V +G VL KL +A+ + Q+SL Q + + L+R++EL Sbjct: 104 NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQ-TRYQILSRSIEL 162 Query: 135 KKSGYVSEQLLDENRTQLASLEAGKKRLLASLQANQLKRDKSQLLA 180 K +L + ++ + L SL Q ++Q Sbjct: 163 NK----LPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQ 204 Score = 39.8 bits (93), Expect = 1e-05 Identities = 29/166 (17%), Positives = 58/166 (34%), Gaps = 22/166 (13%) Query: 101 RLLDAEHQ--EIQASLAQTQADVDLATSTLNR---NLELKKSGYVSEQL--LDENRTQLA 153 +L+ E++ E L ++ ++ S + +L + +E L L + + Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 154 SLEAGKKRLLASLQANQLKRDKSQLLAPFNGIISQRQ-HNLGEVVEAGSPVFILVGSVNT 212 L L N+ ++ S + AP + + Q + H G VV + ++V +T Sbjct: 313 LLTL-------ELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT 365 Query: 213 -EAYIGVPVAVAQQFVNGQNVTV--SVHNQQ----FTAKIAGISAE 251 E V GQN + K+ I+ + Sbjct: 366 LEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLD 411
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 74.3 bits (182), Expect = 1e-18 Identities = 40/197 (20%), Positives = 68/197 (34%), Gaps = 5/197 (2%) Query: 11 RSEQKKQQVLVAAIDLFCRQGFPHTSMDEVAKQAGVSKQTVYSHYGSKDDLFVAAIE--S 68 +++ +Q +L A+ LF +QG TS+ E+AK AGV++ +Y H+ K DLF E Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 69 KCVGHNLNADLLSDPSQPEATLTEFALQFGEMIVSPEAITVFKACVAQSESHP---EVSR 125 +G P P + L E + E V+ E + + V + Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQ 127 Query: 126 LFFEAGPQHMLAMLTKYLGAVEALGVYRFSQPHHCAVRLCLMLFGELKLRLELGLETESL 185 + + L + A + L ++ L Sbjct: 128 QAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDL 187 Query: 186 LGEREQYIRGCAEMFLK 202 E Y+ EM+L Sbjct: 188 KKEARDYVAILLEMYLL 204
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 28.6 bits (64), Expect = 0.032 Identities = 29/122 (23%), Positives = 42/122 (34%), Gaps = 32/122 (26%) Query: 79 DKQWS-----IGMRVGYDRLDYDWRNIRLTGANNAAGLFSDAG--ETWENIDRYRAGLSL 131 D W IG++ G+ +L G N + D G W++ Y + Sbjct: 88 DSGWGNRQSFIGLKGGFGKLRV--------GRLN--SVLKDTGDINPWDSKSDYLGVNKI 137 Query: 132 SYRMDKHWS--------FMLSPQLQYAYADTASASNAQSYGVVASAMYAFESGNMLGFGV 183 + + S LS +QYA D A N++SY A Y GF V Sbjct: 138 AEPEARLISVRYDSPEFAGLSGSVQYALNDNAGRHNSESYH--AGFNYKNG-----GFFV 190 Query: 184 AY 185 Y Sbjct: 191 QY 192
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 448 bits (1155), Expect = e-157 Identities = 172/480 (35%), Positives = 263/480 (54%), Gaps = 19/480 (3%) Query: 7 RILLVGTPSERLSRLCCIFEFLGEQIEII-STEKLSSCLQDTRYRALVLTTDNM----SV 61 IL+ + + L G + I + L + LV+T M + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGD-LVVTDVVMPDENAF 63 Query: 62 EALKSLANQYPWQPILL---FGNVGDLQVSNVLG---QIEEPLNYPQLTELLHFCQVYGQ 115 + L + P P+L+ ++ G + +P + +L ++ + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 116 VKRPQVPTSANQTKLFRSLVGRSEGIANVRHLISQVATSDATVLVLGQSGTGKEVVARNI 175 + ++ + LVGRS + + +++++ +D T+++ G+SGTGKE+VAR + Sbjct: 124 RRPSKLEDDSQD---GMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 176 HYLSERRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAISSRKGRFELAEGGTLFLDEI 235 H +RR+GPF+ +N AIP +L+ESELFGHEKG+FTGA + GRFE AEGGTLFLDEI Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 236 GDMPLQMQVKLLRVLQERVFERVGGTKTINADVRVVAATHRDLESMITSNEFREDLYYRL 295 GDMP+ Q +LLRVLQ+ + VGG I +DVR+VAAT++DL+ I FREDLYYRL Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 296 NVFPIEMPALSDRKDDVPLLLQELVSRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSN 355 NV P+ +P L DR +D+P L++ V + EG RF Q A+E +K H W GNVREL N Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELEN 360 Query: 356 LVERLTILYPGGLVDVNDLPIKYRHIDVPEYSIELSEEQQERDALASIFTSEEPVEIPET 415 LV RLT LYP ++ + + R ++P+ IE + + +++ EE + Sbjct: 361 LVRRLTALYPQDVITREIIENELRS-EIPDSPIEKAAARSGSLSISQAV--EENMRQYFA 417 Query: 416 RFPSELPPEGVNLKDLLAELEIDMIRQALEQQDNVVARAAEMLGIRRTTLVEKMRKYGMT 475 F LPP G+ +LAE+E +I AL +AA++LG+ R TL +K+R+ G++ Sbjct: 418 SFGDALPPSGL-YDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 463 bits (1194), Expect = e-163 Identities = 171/483 (35%), Positives = 251/483 (51%), Gaps = 43/483 (8%) Query: 1 MSEAKLLLVEDDASLREALLDTLMLAQYDCIDVASGEEAIIALKQHQFDLVISDVQMQGI 60 M+ A +L+ +DDA++R L L A YD ++ + DLV++DV M Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 GGLGLLNYLQQHHPKLPVLLMTAYATIGSAVSAIKLGAVDYLAKPFAPEVLLNQVSRYLP 120 LL +++ P LPVL+M+A T +A+ A + GA DYL KPF L+ + R L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 LKQSSDQPVVAD-----------EKSLALLSLAQRVAASDASVMILGPSGSGKEVLARYI 169 + + D + + R+ +D ++MI G SG+GKE++AR + Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 170 HQHSSRANQAFVAINCAAIPENMLEATLFGYEKGAFTGAYQACPGKFEQAQGGTLLLDEI 229 H + R N FVAIN AAIP +++E+ LFG+EKGAFTGA G+FEQA+GGTL LDEI Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 230 SEMDLGLQAKLLRVLQEREVERLGGRKTIKLDVRVLATSNRDLKAVVAAGQFREDLYYRI 289 +M + Q +LLRVLQ+ E +GGR I+ DVR++A +N+DLK + G FREDLYYR+ Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 290 NVFPLTWPALNQRPADILPLARHLLAKHAKALNVLDLPEFDEAACRRLLSHRWPGNVREL 349 NV PL P L R DI L RH + + K LD+ FD+ A + +H WPGNVREL Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAEK--EGLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 350 DNVVQRALILRAGAVITANDIIIDAQDV---------------------------PLLSD 382 +N+V+R L VIT I + + + Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 383 DAEYVNEPEGLGEELKAQEHVIILETLAQCQGSRKLVAEKLGISARTLRYKMARMRDMGI 442 + + L E+ +IL L +G++ A+ LG++ TLR K +R++G+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKK---IRELGV 475 Query: 443 QLP 445 + Sbjct: 476 SVY 478
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 60.1 bits (145), Expect = 3e-15 Identities = 32/101 (31%), Positives = 55/101 (54%) Query: 12 MQSLKGEIAPSFGISPNNIVQQVNNTSGADFGQLLSQAIGNVSGLQSTSSNLATRLEMGD 71 +Q ++G I+ + + Q+ F L A+ +S Q+ + A + +G+ Sbjct: 3 IQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGE 62 Query: 72 TTVSLSDTVIAREKASVAFEATVQVRNKLVEAYKEIMSMPV 112 V+L+D + +KASV+ + +QVRNKLV AY+E+MSM V Sbjct: 63 PGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 297 bits (762), Expect = 4e-96 Identities = 160/567 (28%), Positives = 263/567 (46%), Gaps = 57/567 (10%) Query: 26 LGGVDMMRQITMILALAICLALAVFVMIWAQEPEYRPL-GKMETQEMVQVLDVLDKNKIK 84 L + +I +I+A + +A+ V +++WA+ P+YR L + Q+ ++ L + I Sbjct: 16 LNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIP 75 Query: 85 YQIDVD--VVKVPEDKYQEVKMMLSRAGIDSAAASSKDFLTQDSGFGVSQRMEQARLKHS 142 Y+ ++VP DK E+++ L++ G+ A + L Q FG+SQ EQ + + Sbjct: 76 YRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQ-EKFGISQFSEQVNYQRA 134 Query: 143 QEENLARAIEQLQSVSRAKVILALPKENVFARNTAQPSATVVINTRRG-GLGQGEVDAIV 201 E LAR IE L V A+V LA+PK ++F R PSA+V + G L +G++ A+V Sbjct: 135 LEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVV 194 Query: 202 DIVASAVQGLEPSRVTVTDSNGRLLNSGSQDGVSARARRELELVQQKEAEYRTKIDSILS 261 +V+SAV GL P VT+ D +G LL + G +L+ E+ + +I++ILS Sbjct: 195 HLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDL-NDAQLKFANDVESRIQRRIEAILS 253 Query: 262 PILGPDNFTSQVDVSMDFTAVEQTAKRFNPDLPSLRSEMTVENNST-----GGSTGGIPG 316 PI+G N +QV +DF EQT + ++P+ + ++ + + G GG+PG Sbjct: 254 PIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPG 313 Query: 317 ALSNQPP---------------MESNIPQEA-DKATESVTAGNSHREATRNFELDTTISH 360 ALSNQP N PQ + + S ++ R T N+E+D TI H Sbjct: 314 ALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDRTIRH 373 Query: 361 TRQQIGVVRRVSVSVAVDFKPGAAGENGQVARVARTEQELTNIRRLLEGAVGFSAQRGDV 420 T+ +G + R+SV+V V++K A G+ + T ++ I L A+GFS +RGD Sbjct: 374 TKMNVGDIERLSVAVVVNYKTLADGKP-----LPLTADQMKQIEDLTREAMGFSDKRGDT 428 Query: 421 LEVVTVPFMDQLVEDVPAPELWEQPWFWRAVKLGVGALVILV----LILAVVRPMLKRLI 476 L VV PF + W+Q F + L++LV L VRP L R + Sbjct: 429 LNVVNSPF-SAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLTRRV 487 Query: 477 YPDNVNMPEDSRLGNELAEIEDQYAADTLGMLNTKEAEYSYADDGSIL---IPNLHKDDD 533 E E+ E + D + + Sbjct: 488 E----EAKAAQEQAQVRQETEE-------------AVEVRLSKDEQLQQRRANQRLGAEV 530 Query: 534 MIKAIRALVANEPELSTQVVKNWLQDN 560 M + IR + N+P + V++ W+ ++ Sbjct: 531 MSQRIREMSDNDPRVVALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 290 bits (743), Expect = 9e-99 Identities = 109/348 (31%), Positives = 194/348 (55%), Gaps = 5/348 (1%) Query: 1 MAENKSKDAAEAPSFNIKDLSGIEKTAILLLSLSEADAASILKHLEPKQVQKVGMAMAAM 60 M E K K+ + + L+G +K AILL+S+ ++ + K+L ++++ + +A + Sbjct: 1 MEEKKEKEILD-----VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKL 55 Query: 61 EDFGQEKVIGVHKLFLDDIQKYSSIGFNSEEFVRKALTAALGEDKAGNLIEQIIMGSGAK 120 E E V F + + I ++ R+ L +LG KA ++I + ++ Sbjct: 56 ETITSELKDNVLLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSR 115 Query: 121 GLDSLKWMDARQVATIIQNEHPQIQTIVLSYLEPDQAAEIFGQFPENTRLDLMMRIANLE 180 + ++ D + IQ EHPQ ++LSYL+P +A+ I P + ++ RIA ++ Sbjct: 116 PFEFVRRADPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMD 175 Query: 181 EVQPAALQELNDIMEKQFAGQGGAQAAKMGGLKAAANIMNYLDTGVESQLMETMRETDEE 240 P ++E+ ++EK+ A GG+ I+N D E ++E++ E D E Sbjct: 176 RTSPEVVREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPE 235 Query: 241 MAQQIQDLMFVFENLIDVDDRGIQTLLREVQQDVLMKALKGTDDQLKDKILGNMSKRAAE 300 +A++I+ MFVFE+++ +DDR IQ +LRE+ L KALK D +++KI NMSKRAA Sbjct: 236 LAEEIKKKMFVFEDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAAS 295 Query: 301 LLRDDLEAMGPIRISEVEIAQKEILSIARRLSDSGEIMLGGGGGDEFL 348 +L++D+E +GP R +VE +Q++I+S+ R+L + GEI++ GG ++ L Sbjct: 296 MLKEDMEFLGPTRRKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 86.4 bits (213), Expect = 5e-22 Identities = 58/201 (28%), Positives = 103/201 (51%), Gaps = 4/201 (1%) Query: 54 APKAVAAETIAPPTMAEIEDIRAQAEEEGFN---EGKTQGYAEGLEQGRLEGLEQGHTEG 110 AP I P IE+ E++ + QGY G+ +GR +G +QG+ EG Sbjct: 16 APPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEG 75 Query: 111 LVQGHEQGLEAGLAEAKTLIQRFEGLLSQFEKPLQLLDGDIEHSLMTLTMALAKSVIGHE 170 L QG EQGL ++ + R + L+S+F+ L LD I LM + + A+ VIG Sbjct: 76 LAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQT 135 Query: 171 LKTHPEQILSALRLGVESLPIKEQSVSIRMHPDDVALVEQLYTSTQLNRNQWQLEAEPSL 230 ++ ++ ++ P+ +R+HPDD+ V+ + +T L+ + W+L +P+L Sbjct: 136 PTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT-LSLHGWRLRGDPTL 194 Query: 231 NPGDCIISSQRSLVDLTLSSR 251 +PG C +S+ +D ++++R Sbjct: 195 HPGGCKVSADEGDLDASVATR 215
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 42.9 bits (100), Expect = 6e-08 Identities = 36/145 (24%), Positives = 71/145 (48%) Query: 1 MANADPLLLVLKLALDAEEQAALLLKSAQLECQKRQNQLDALNNYRLDYMKQMQSQQGQA 60 MA L + LA E AA LL + CQ+ + QL L +Y+ +Y + S Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 ISASHYHQFHRFIRQIDEAIAQQNRVVADGEKQKNYRQQHWLDKQKKRKAVELLLDNKEK 120 I+++ + + +FI+ +++AI Q + + ++ + W +K+++ +A + L + + Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 KRQALELKKEQKMTDEFASQQFFRR 145 E + +QK DEFA + R+ Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRK 145
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 50.6 bits (120), Expect = 9e-09 Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Query: 460 MKQQLVTMVSQGIQQAEIRLDPPELGHMLVKVQVHGDQTQVQFHVTQAQTRDVVEQAIPR 519 + Q + QG Q AE+RL P +LG + + ++V +Q Q+Q R +E A+P Sbjct: 244 LSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAALPV 303 Query: 520 LRELLQEQGLQLADSHVSQGDQGQRREGGFGEAGGSSGGNVDDFSAEELD-----LGLNQ 574 LR L E G+QL S++S +++ + N + + E+ D + L Sbjct: 304 LRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVSLQG 363 Query: 575 ATSLNSGIDYYA 586 + NSG+D +A Sbjct: 364 RVTGNSGVDIFA 375
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 249 bits (637), Expect = 7e-83 Identities = 88/327 (26%), Positives = 165/327 (50%), Gaps = 12/327 (3%) Query: 1 MSDLLSQDEIDALLHGVDDVEEDNELDAAGLEARS----YDFSSQDRIVRGRMPTLEIVN 56 M+++LSQDEID LL + + E DA + YDF D+ + +M TL +++ Sbjct: 1 MTEVLSQDEIDQLLTAISSGDASIE-DARPISDTRKITLYDFRRPDKFSKEQMRTLSLMH 59 Query: 57 ERFARHLRISMFNMMRRAAEVSINGVQMLKFGEYVHTLFVPTSLNMVRFHPLKGTALITM 116 E FAR S+ +R V + V L + E++ ++ P++L ++ PLKG A++ + Sbjct: 60 ETFARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEV 119 Query: 117 EARLVFILVDNFFGGDGRFHAKIEGREFTPTERRIVQLLLKIIFEDYKDAWAPVMDVEFD 176 + + F ++D FGG G+ R+ T E +++ ++ I + +++W V+D+ Sbjct: 120 DPSITFSIIDRLFGGTGQAAKVQ--RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPR 177 Query: 177 YLDSEVNPAMANIVSPTEVVVINSFHIEVDGGGGDFHITMPYSMIEPIRELLDAG--VQS 234 E NP A IV P+E+VV+ + +V G + +PY IEPI L + S Sbjct: 178 LGQIETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSS 237 Query: 235 DKQDTDMRWSQALHDEIMDVKVGFDATVVEHELTLKDVMNFKAGDIIPIE---LPEYIMM 291 ++ + ++ L D++ V + A V L+++D++ + GDII + + + ++ Sbjct: 238 VRRSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVL 297 Query: 292 KIEDLPTYRCKMGRSRDNLALKIYEKI 318 I + + C+ G +A +I E+I Sbjct: 298 SIGNRKKFLCQPGVVGKKIAAQILERI 324
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 111 bits (278), Expect = 9e-35 Identities = 54/122 (44%), Positives = 81/122 (66%) Query: 2 STDDDWAAAMAEQALEEANAIDLDELVDDSQPISKAEAAKLDTILDIPVTISMEVGRSYI 61 + DD WA A+ EQ + +D I+DIPV +++E+GR+ + Sbjct: 14 ALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDIPVKLTVELGRTRM 73 Query: 62 SIRNLLQLNQGSVVELDRVAGEPLDVMVNGTLIAHGEVVVVNDKFGIRLTDVISQTERIK 121 +I+ LL+L QGSVV LD +AGEPLD+++NG LIA GEVVVV DK+G+R+TD+I+ +ER++ Sbjct: 74 TIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRITDIITPSERMR 133 Query: 122 KL 123 +L Sbjct: 134 RL 135
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 275 bits (705), Expect = 4e-96 Identities = 122/240 (50%), Positives = 176/240 (73%) Query: 8 LIGVSTLLFAASVGAADGVLPAVTVKTAADGSTEYSVTMQILLLMTSLSFIPAMVIMLTS 67 L+ V+ +L A LP +T + G +S+ +Q L+ +TSL+FIPA+++M+TS Sbjct: 4 LLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTS 63 Query: 68 FTRIIVVLSILRQAIGLQQTPSNQVLIGMSLFMTFFIMAPVFDKIYDQGVKPYIDEQLTL 127 FTRII+V +LR A+G P NQVL+G++LF+TFFIM+PV DKIY +P+ +E++++ Sbjct: 64 FTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISM 123 Query: 128 QQAFDKGKEPLRAFMLGQVRTTDLKTFIDISGYQNINSPEEAPMSVLVPAFITSELKTAF 187 Q+A +KG +PLR FML Q R DL F ++ + PE PM +L+PA++TSELKTAF Sbjct: 124 QEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAF 183 Query: 188 QIGFMLFVPFLVLDLVVASILMAMGMMMLSPMIVSLPFKIMLFVLVDGWGLVMGTLANSF 247 QIGF +F+PFL++DLV+AS+LMA+GMMM+ P ++LPFK+MLFVLVDGW L++G+LA SF Sbjct: 184 QIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQSF 243
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 47.1 bits (112), Expect = 1e-10 Identities = 20/73 (27%), Positives = 39/73 (53%) Query: 4 EALIDIFREALAVIVMMVSAIVLPGLGIGLIVAVFQAATSINEQTLSFLPRLIVTLLALM 63 + L+ +AL +++++ + IGL+V +FQ T + EQTL F +L+ L L Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 VMGHWLVQTLMDF 76 ++ W + L+ + Sbjct: 62 LLSGWYGEVLLSY 74
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 124 bits (314), Expect = 1e-36 Identities = 95/243 (39%), Positives = 142/243 (58%), Gaps = 1/243 (0%) Query: 15 YMWPLFRVTSMLMVMVVFGATTTPTRVRLLLAVAITLAIAPVLPPVKDAELFSLSAVFIT 74 Y WPL RV +++ + + P RV+L LA+ IT AIAP LP D +FS A+++ Sbjct: 16 YFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLP-ANDVPVFSFFALWLA 74 Query: 75 AQQIIIGVAMGFVTQMVMQTFVLTGQIIGMQTSLGFASMVDPGSGQQTPVIGNFFLLLAT 134 QQI+IG+A+GF Q G+IIG+Q L FA+ VDP S PV+ +LA Sbjct: 75 VQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLAL 134 Query: 135 LIFLAVDGHLLMIRMLVASFETLPISNQGLTLTSYRALAEWGSYMFGAALTMSLSAIIAL 194 L+FL +GHL +I +LV +F TLPI + L ++ AL + GS +F L ++L I L Sbjct: 135 LLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLALPLITLL 194 Query: 195 LLVNLSFGVMTRAAPQLNIFSIGFPITMIGGLLILWLTLTPVMAHFEEVWASAQLLLCDI 254 L +NL+ G++ R APQL+IF IGFP+T+ G+ ++ + + E +++ LL DI Sbjct: 195 LTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIFNLLADI 254 Query: 255 LGL 257 + Sbjct: 255 ISE 257
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 338 bits (868), Expect = e-117 Identities = 97/347 (27%), Positives = 178/347 (51%), Gaps = 2/347 (0%) Query: 6 SGERSEEPTGRRLEQAREKGQVARSKELGTATVLLSAATGLYMLGPGIAKALSNVFERVF 65 SGE++E+PT +++ AR+KGQVA+SKE+ + ++++ + L L + S + + Sbjct: 2 SGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLM--LI 59 Query: 66 TMDRAAIFDTNQMFNVWGVVGSEIGWPLLKIMLLIVVVAFIGNVSLGGMNFSTQAMMPKA 125 +++ + + + V V E + ++ + ++A +V G S +A+ P Sbjct: 60 PAEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDI 119 Query: 126 SKMSPIAGFKRMFGVQALVELTKGIAKFSVVAIAAYLLLSHYFNDILLLSADHLPGNVHH 185 K++PI G KR+F +++LVE K I K +++I ++++ +L L + Sbjct: 120 KKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPL 179 Query: 186 ALDLLVWMFILLCSSVLVIVVIDVPFQIWNHNKQLKMTKQEVKDEYKDTEGKPEVKGRVR 245 +L + ++ +VI + D F+ + + K+LKM+K E+K EYK+ EG PE+K + R Sbjct: 180 LGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRR 239 Query: 246 QMQRELAQRRMMAEVPNADVIVVNPEHYAVAIKYDVKRSAAPFVIAKGVDEVAFKIREVA 305 Q +E+ R M V + V+V NP H A+ I Y + P V K D +R++A Sbjct: 240 QFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIA 299 Query: 306 RAHNIAIVSAPPLARAIYHTTKLEQQIPEGLFTAVAQVLAYVFQLRQ 352 + I+ PLARA+Y ++ IP A A+VL ++ + Sbjct: 300 EEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNI 346
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.027 Identities = 25/158 (15%), Positives = 51/158 (32%), Gaps = 19/158 (12%) Query: 485 VVDAATVVATHISQILTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDV-MPLGNVVK 543 V D + T ++Q L+ + L +A LV + DV MP N Sbjct: 8 VADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLV---VTDVVMPDENAFD 64 Query: 544 VMQNLLNEGVSVR--------DLRTIVQTL----LEYGTKSNDTEVLTAAVRIAL---KR 588 ++ + + T ++ +Y K D L + AL KR Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 589 MIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGP 626 + + +P++ + ++++ + D Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLT 162
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.013 Identities = 9/25 (36%), Positives = 12/25 (48%) Query: 238 VKQGGVVALVGPTGVGKTTSLAKLA 262 K V L G G+GK+T + L Sbjct: 593 CKFDYSVVLEGTGGIGKSTLINTLV 617
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.9 bits (223), Expect = 3e-24 Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 6 KILIVDDFSTMRRIIKNLLRDLGFNNTQEADDGSTALPMLQKGDFDFVVTDWNMPGMQGI 65 IL+ DD + +R ++ L G++ + +T + GD D VVTD MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 DLLKAIRADDSLKHLPVLMVTAEAKREQIIAAAQAGVNGYVVKPF 110 DLL I+ LPVL+++A+ I A++ G Y+ KPF Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>PF06580#Sensor histidine kinase Length = 349 Score = 44.1 bits (104), Expect = 2e-06 Identities = 19/105 (18%), Positives = 37/105 (35%), Gaps = 23/105 (21%) Query: 452 TLNKEIDLVLV---------GEETDLDKNLVEALADPLVH------LVRNSVDHGIEMPN 496 +L E+ +V + + + A+ D V LV N + HGI Sbjct: 217 SLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA--- 273 Query: 497 DREASGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIAI 541 P+ G I L +++ + L++E+ G+ + Sbjct: 274 -----QLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGT 313
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 2e-13 Identities = 28/135 (20%), Positives = 56/135 (41%), Gaps = 7/135 (5%) Query: 2 AIKVLVVDDSSFFRRRVSEIVNQDPELEVIATASNGAEAVKMAAELNPQVITMDIEMPVM 61 +LV DD + R +++ +++ + SN A + A + ++ D+ MP Sbjct: 3 GATILVADDDAAIRTVLNQALSR--AGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGITAVREIMAKCP-TPILMFSSLTHDGAKATLDALDAGALDFLPKRF--EDIATNKDDA 118 + + I P P+L+ S+ + + A + GA D+LPK F ++ A Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSA--QNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 119 ILLLQQRVKALGRRR 133 + ++R L Sbjct: 119 LAEPKRRPSKLEDDS 133
>PF06580#Sensor histidine kinase Length = 349 Score = 27.9 bits (62), Expect = 0.045 Identities = 15/103 (14%), Positives = 35/103 (33%), Gaps = 7/103 (6%) Query: 21 GFGLIKRKGLRTFVFIPLMINLVLFAAVIYVAIGQLDVLFTWMNAQLPEYLSWLNF---- 76 G+G+ L F F L + L + + +AI + ++ T + WL Sbjct: 19 GWGVY---TLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQ 75 Query: 77 LLWPLAVTTMLVMLAFVFSSVMNWLAAPFNGLLAEKVEQLLTG 119 ++ + +++ + + ++ W F L Sbjct: 76 IILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLAL 118
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 43.5 bits (102), Expect = 4e-06 Identities = 41/293 (13%), Positives = 103/293 (35%), Gaps = 9/293 (3%) Query: 616 AKQDNSQSLVQLSKEQTELSEAIADCEQAKAIQQAKLDELAQQLAQVRDSLSQGTKRLHQ 675 A + + +L ++ + + + + L ++ + LS ++L + Sbjct: 44 ATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRK 103 Query: 676 LQLDKATKSTQLNNAEIQAKQREAKRGQLAETLARTHAELAELAEQLILLAEQEDELAEA 735 + K++++ E + E A++ L + LA ++ +L +A Sbjct: 104 NDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKA 163 Query: 736 LEVSLEQQQQQSQDAQGDMARHQALKAQIGDAERRLTSLNASLQSIATRMAVSTEQIELQ 795 LE ++ S + A AL+A+ + E+ L + + ++ + Sbjct: 164 LEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAAL 223 Query: 796 RVRVSELVHSKETLSA--QLANVAAQEGDQQTAQLSEQLAQLLNQQQSQQQALKSLRSQQ 853 R ++L + E + + + + A L + A+L + + ++ Sbjct: 224 AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 283 Query: 854 SSLTETLNSIGLKQKQELGKLEGLTQSLSTLKLRREGLKGQADSQLAALSEQQ 906 +L + E LE +Q L+ R+ L+ D+ A + + Sbjct: 284 KTLEAEKA----ALEAEKADLEHQSQVLNA---NRQSLRRDLDASREAKKQLE 329 Score = 42.7 bits (100), Expect = 7e-06 Identities = 50/283 (17%), Positives = 96/283 (33%), Gaps = 12/283 (4%) Query: 227 KTHAELLVMRYQELQSQMASLSEQISSLELQQAAAQSLAQTGELESTELQLTLSHLAEQE 286 K L + L+ L+E++S+ + + + EL+ + L + Sbjct: 70 KLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKAL 129 Query: 287 QQAVEAYYLTGTEIAKLEQQLQSQKLRDAQLHNQLEQLSEQIIQNQAKLAAYQASFQALE 346 + A+ +I LE + + R A L LE + AK+ +A ALE Sbjct: 130 EGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALE 189 Query: 347 AELSQLGPQHELQQEMLDELQAQWEMSVSRSEAQSESARVLAAAVAQHKLQLELHRSKLA 406 A ++L E A+ + + A + L A+ +K+ Sbjct: 190 ARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIK 249 Query: 407 HQQQLNAHKTLLHQEQQQELASLNAHALEDSSASLNDEIAQLEQALAEQVEINQEFESTL 466 + A + +Q EL E + + A+++ AE+ + E Sbjct: 250 TLEAEKAAL----EARQAELEKAL----EGAMNFSTADSAKIKTLEAEKAALEAE----K 297 Query: 467 AADTHALDLARGEFEQLSQRLTSMRARFELVEQWLAKQEELSD 509 A H + + L + L + R + +E K EE + Sbjct: 298 ADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNK 340 Score = 40.4 bits (94), Expect = 4e-05 Identities = 29/182 (15%), Positives = 68/182 (37%), Gaps = 7/182 (3%) Query: 188 RENLERLGDIRSELAKQLEKLSQQAKAAKQYRELKQAERKTHAELLVMRYQELQSQMASL 247 + +LE+ + + + +A K E +QAE + E + +++ +L Sbjct: 157 KADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTL 216 Query: 248 SEQISSLELQQAAAQSLAQTGELESTELQLTLSHLAEQEQQAVEAYYLTGTEIAKLEQQL 307 + ++L ++A + + ST + L ++ A+LE+ L Sbjct: 217 EAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEA-------RQAELEKAL 269 Query: 308 QSQKLRDAQLHNQLEQLSEQIIQNQAKLAAYQASFQALEAELSQLGPQHELQQEMLDELQ 367 + +++ L + +A+ A + Q L A L + +E +L+ Sbjct: 270 EGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLE 329 Query: 368 AQ 369 A+ Sbjct: 330 AE 331 Score = 39.3 bits (91), Expect = 1e-04 Identities = 43/265 (16%), Positives = 92/265 (34%), Gaps = 15/265 (5%) Query: 146 QGTISRLIESKPQDLRTFIEEAAGISRYKERRRETENRIRHTRENLERLGDIRSELAKQL 205 +S E ++ ++ E+A+ I + R+ + E + L + Sbjct: 91 TEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEK 150 Query: 206 EKLSQQAKAAKQYRELKQAERKTHAELLVMRYQELQSQMASLSEQISSLELQQAAAQSLA 265 L+ + ++ E + + + L+++ A+L + + LE A + + Sbjct: 151 AALAARKADLEKALEGAMNFSTADSA----KIKTLEAEKAALEARQAELEKALEGAMNFS 206 Query: 266 QTGELESTELQLTLSHLAEQEQQAVEAYYLTGTEIAKLEQQLQSQKLRDAQLHNQLEQLS 325 + L+ + LA ++ +A ++++ + A L + +L Sbjct: 207 TADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELE 266 Query: 326 EQIIQNQAKLAAYQASFQALEAELSQLGPQHELQQEMLDELQAQWEMSVSRSEAQSESAR 385 + + A A + LEAE + L+ +A E A +S R Sbjct: 267 KALEGAMNFSTADSAKIKTLEAE-----------KAALEAEKADLEHQSQVLNANRQSLR 315 Query: 386 VLAAAVAQHKLQLELHRSKLAHQQQ 410 A + K QLE KL Q + Sbjct: 316 RDLDASREAKKQLEAEHQKLEEQNK 340
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 35.4 bits (81), Expect = 4e-04 Identities = 16/106 (15%), Positives = 38/106 (35%), Gaps = 7/106 (6%) Query: 504 MLDRMGMKSATNLAQAIEAAKTTTLPRFLYALGIREVGEATASNLAT---HFGSLEALRV 560 M + ++ ++ A + + + + E+ +A HF L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 561 ATIEQLIQVEDIGEVVAQHVAHFFAQPHNL--EVIDALIAAGVNWP 604 E +IGE+ ++ A F P ++ E++ ++ + V Sbjct: 61 EIWEL--SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEE 104
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.039 Identities = 10/51 (19%), Positives = 19/51 (37%), Gaps = 1/51 (1%) Query: 1 MELSVVNQKSVAVVGCG-WFGFALAKHLVQAGYRVTGAKRHTEELAPLTEA 50 M + K + G G A+A+ L G + + E+L + + Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSS 51
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 64.9 bits (158), Expect = 2e-13 Identities = 67/395 (16%), Positives = 140/395 (35%), Gaps = 37/395 (9%) Query: 31 SKQRDTRLMWALCVASVVVYINLYLMQGMLPLIAEHFAVSGSKATLILSVTSFSLAFSLL 90 S R +++ LC+ S +N ++ LP IA F + + + + + Sbjct: 8 SNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTA 67 Query: 91 IYAVVSDRIGRHTPIVVSLWLLALSNLL-LIWAGDFNALVYVRFLQGVLLAAVPAIAMAY 149 +Y +SD++G ++ + + +++ + F+ L+ RF+QG AA PA+ M Sbjct: 68 VYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 150 FKEQLSPSTMLKAAGIYIMANSIGGIVGRLLGGVMSQFLSWQESMWLLFLVTLAGVALTS 209 + KA G+ ++G VG +GG+++ ++ W + L+ ++T+ V Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS-YLLLIPMITIITVPFLM 186 Query: 210 YLLPSGA---------DAQAVSGGQTTSPTLSKRARLL-------------QDIYGFSHH 247 LL +S G + + + I + Sbjct: 187 KLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDP 246 Query: 248 LTDPQM------RLAYAIGGITFMMMVNQFSFIQLHLMAAPYEWSRFQA--TLIFLCYSS 299 DP + + GGI F + S + +M ++ S + +IF S Sbjct: 247 FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPY-MMKDVHQLSTAEIGSVIIFPGTMS 305 Query: 300 GTVASYFTAKWLAKFGQHKLYQWSWCLMLLGSL---LTLFDTPVTICLGFLMTACGFFLT 356 + Y + + G + + + L L T + + + G T Sbjct: 306 VIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFT 365 Query: 357 HSCCNSFVAMRAS-RDRAKATSLYLCCYYLGAALG 390 + ++ V+ ++ SL +L G Sbjct: 366 KTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTG 400
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 503 bits (1298), Expect = e-164 Identities = 215/1047 (20%), Positives = 451/1047 (43%), Gaps = 72/1047 (6%) Query: 3 LTRLAIKRPVTTSMFFFAILLFGLASSRLLPLEMFPGIDIPQIVVQVPYKGSTPAEVERD 62 + I+RP+ + +++ G + LP+ +P I P + V Y G+ V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 ITKVLEESLATMGGIDELESESSQEG-AEIEINMKWGENVATKSLEAREKIDAVRHLLPK 121 +T+V+E+++ + + + S S G I + + G + ++ + K+ LLP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 DVERVFIRQFSTADMPVLTIRISSDRELSGAFDLLD---KQLKRPLERVEGVSKVNLYGV 178 +V++ I ++ ++ SD + D+ D +K L R+ GV V L+G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 179 EQKQIEVRINANRLAASGYSATELQTRLGRENFVLSAGTL------RESNLVYQVSPKGE 232 Q + + ++A+ L + ++ +L +N ++AG L L + + Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 233 FRNLEDIKALVLLPGLT-----LGDVANVQFALPERVEGRHLDKHYAVGLDVFKESGANL 287 F+N E+ + L L DVA V+ ++ A GL + +GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 288 VEVSDRVLKVIELAKQDQQF-QGIRLFIMEDQASGVKSSLSDLLLSGLIGALLSFIVLYL 346 ++ + + +LA+ F QG+++ D V+ S+ +++ + +L F+V+YL Sbjct: 300 LDTAKAIKA--KLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYL 357 Query: 347 FLRNFKMTLIVVSSVPISIGMTLAAMYLLGYSLNILSMMGLLLAVGMLIDNAVVVTESVL 406 FL+N + TLI +VP+ + T A + GYS+N L+M G++LA+G+L+D+A+VV E+V Sbjct: 358 FLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVE 417 Query: 407 QEKQGKDTKSAEDNENAVMTGVDKVSLAVLAGTMTTAIVFLPNIFGVKVELTIFLEHVAI 466 + E A + ++ A++ M + VF+P F I+ + +I Sbjct: 418 RVMMEDKLPPKE----ATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQ-FSI 472 Query: 467 AICISLAASLLVAKTLIPLMLTKFHFDIAPEKAPGK-------------LQNFYNRSLNW 513 I ++A S+LVA L P + ++ E K N Y S+ Sbjct: 473 TIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGK 532 Query: 514 VLLRPWRSGLISVAILVSTALPLSMVKQDQEDSQSKERIYINYQVEGRHNLNVTEAMVSQ 573 +L R LI I+ + + + + Q+ T+ ++ Q Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 574 MEEYLYNNKEEFHIDSVYSYY-------APDDASSVILLK--KDLPMPLDELKKKIRSGF 624 + +Y N++ +++SV++ A + + + LK ++ + + I Sbjct: 593 VTDYYLKNEKA-NVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAK 651 Query: 625 PKFSIAKPQFGWGNDNSGVRVTLTGRST--------------SELIHLSEQVLPLLS-NI 669 + K + G+ + + G +T L Q+L + + + Sbjct: 652 MEL--GKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHP 709 Query: 670 KGLVDVRSEVNGAQQEVVIRINRQMAARLDLKLNEVASSISMALRGSPLRSFRHDPNGEL 729 LV VR + + ++++ A L + L+++ +IS AL G+ + F D Sbjct: 710 ASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFI-DRGRVK 768 Query: 730 RIEMAYEKEWQKSLEKLKQLPIVRIDQRLYTLDNLASIEILPRFDTIKHYNRQTSLSIGA 789 ++ + + +++ E + +L + + + + + ++ YN S+ I Sbjct: 769 KLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQG 828 Query: 790 NLDK-LTTEEAQTKIKQVMENVRFPNGYNYSLRGGFERQDEDESVMAINMLLAIAMIYIV 848 ++ +A ++ + + P G Y G ++ + + ++ ++++ Sbjct: 829 EAAPGTSSGDAMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLC 886 Query: 849 MAALFESLLLPTAIITSILFSITGVFWALLLTGTPMSVMAMIGILILMGIVVNNGIVLVD 908 +AAL+ES +P +++ + I GV A L V M+G+L +G+ N I++V+ Sbjct: 887 LAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVE 946 Query: 909 QINQVTPELDK-LSDTIREVCITRLRPVLMTVGTTVLGLVPLAMGETQIGGGGPPYSPMA 967 + + K + + RLRP+LMT +LG++PLA+ G G + + Sbjct: 947 FAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAIS---NGAGSGAQNAVG 1003 Query: 968 IAIIGGLSFSTVTSLYLVPLCYQLLYR 994 I ++GG+ +T+ +++ VP+ + ++ R Sbjct: 1004 IGVMGGMVSATLLAIFFVPVFFVVIRR 1030
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 65.7 bits (160), Expect = 9e-14 Identities = 47/196 (23%), Positives = 78/196 (39%), Gaps = 16/196 (8%) Query: 24 QLLFMLVFMVACGQMAQTIFVPALPLIAQGLAVDASKLQALMACYLLAYGLCQFIYGPLS 83 Q+L L + + + + +LP IA + + ++L + + +YG LS Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 84 DRVGRKIPLLIGIGIFIVGAFMAA-EATSFSQLIFASLLQGLGTA-----SAGALCRSIP 137 D++G K LL GI I G+ + + FS LI A +QG G A + R IP Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 138 RDHYFGDNLVKFNSYVSMAVVFLPLVAPFLGSFASAYFGWQAVYWVLFGFGSFVWLLICF 197 +++ G S V+M P + G + Y W Y +L + + + Sbjct: 134 KENR-GKAFGLIGSIVAMGEGVGPAI----GGMIAHYIHWS--YLLLIPMITIITVPFLM 186 Query: 198 GFKESLPKEKREQQPI 213 L KE R + Sbjct: 187 KL---LKKEVRIKGHF 199
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 45.2 bits (107), Expect = 3e-07 Identities = 28/147 (19%), Positives = 63/147 (42%), Gaps = 10/147 (6%) Query: 111 VNRLKAKLSSQQAIVDKAERDVKRLKPLYEQDAASQLDYDNALSTLAQARSNLTASRAEV 170 +L ++ +++ E ++ K Y+ +QL + L L Q N+ E+ Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQL--VTQLFKNEILDKLRQTTDNIGLLTLEL 318 Query: 171 EEAELELSYTEIKAPIAGLVSRSEV-DIGALVGSKGQSLLTRVKQVDPIYVSFNMSALDY 229 + E + I+AP++ V + +V G +V + ++L+ V + D + V+ + D Sbjct: 319 AKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT-AETLMVIVPEDDTLEVTALVQNKDI 377 Query: 230 ------LNAQRRLTSYSAKKEAEVEGK 250 NA ++ ++ + + GK Sbjct: 378 GFINVGQNAIIKVEAFPYTRYGYLVGK 404 Score = 37.1 bits (86), Expect = 1e-04 Identities = 21/176 (11%), Positives = 60/176 (34%), Gaps = 14/176 (7%) Query: 73 EVRARVDGFVEEKRFVEGSAVKAGELLYQIDNKPYVAVVNRLKAKLSSQ-------QAIV 125 E++ + V+E EG +V+ G++L ++ A + ++ L Q + Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 126 DKAERDVKRLKPLYEQDAASQLDYDNALSTLAQARSNLTASRAEVEEAELELSYTEIKAP 185 E + L ++ + + L + + + + + + EL+ + +A Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQK--YQKELNLDKKRAE 215 Query: 186 IAGLVSRSEVDIGALVGSKGQSLLTRVKQVDPIYVSFNMSALDYLNAQRRLTSYSA 241 +++R I + +R+ + ++ L + + Sbjct: 216 RLTVLAR----INRYENLS-RVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVN 266
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 965 bits (2497), Expect = 0.0 Identities = 426/1028 (41%), Positives = 618/1028 (60%), Gaps = 9/1028 (0%) Query: 1 MAQFFINRPIFASVISIVIVLLGVIAMFKLPVDQYPYITPPQVTISASYPGASSTTAAES 60 MA FFI RPIFA V++I++++ G +A+ +LPV QYP I PP V++SA+YPGA + T ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VATPLEQEVNGVPNMIYMSSKSTNSGSTSVTITFDVGTNADLAAVDVQNSAQQASGGLPI 120 V +EQ +NG+ N++YMSS S ++GS ++T+TF GT+ D+A V VQN Q A+ LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 DVQTEGVTVSKDASVELLKLALTSNDERFDEIYLSNYATINIESALKRIPGVGRTRNTGS 180 +VQ +G++V K +S L+ S++ + +S+Y N++ L R+ GVG + G+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 RSYAMRIWLKPDAMAGYSLTTTDVINAIKAQNKESPAGTIGTQPNNDDISLTLPISVAGR 240 + YAMRIWL D + Y LT DVIN +K QN + AG +G P L I R Sbjct: 181 Q-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 241 LSSVQAFNEIIVRANPDGSIIRLRDIAGVELGSSAYTLQSQLNGENATILQVYLLPGANA 300 + + F ++ +R N DGS++RL+D+A VELG Y + +++NG+ A L + L GANA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 301 LEVTHKVKQAMAELSQKFPQGMKWEVFYDASIFIQESIDEVIHTLIEALVLVVLVVYLFL 360 L+ +K +AEL FPQGMK YD + F+Q SI EV+ TL EA++LV LV+YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 361 QNVRATLIPAIAVPVSLIGTLAAMLAFGFTINTVSLLALVLAIGIVVDDAIVVVENVERL 420 QN+RATLIP IAVPV L+GT A + AFG++INT+++ +VLAIG++VDDAIVVVENVER+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 421 IHEKGMSAIDATRIAMKELSGALVATSLVLCAVFVPVSFLAGITGIMYREFAVAITVAVL 480 + E + +AT +M ++ GALV ++VL AVF+P++F G TG +YR+F++ I A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 481 ISTLVALTLSPALCALLLKPSKAP----QRGFFHWLNRKLDLGTNQYVGLVALTNKYAKR 536 +S LVAL L+PALCA LLKP A + GFF W N D N Y V R Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 537 SYLAFAIMFGGTYFIMSHLPSSFMPDEDQGRFFIDMTLPDGSTVNRTEAILKKAEQYVRA 596 L +A++ G + LPSSF+P+EDQG F + LP G+T RT+ +L + Y Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 597 NPAV-AYSFTLAGENRRSGANQANGQFEVVLKPWAEREASHATVQSVMKAIDKDLKNVLE 655 N S SG Q G V LKPW ER + ++V+ +L + + Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 656 AEFNLYLPSAVPGLGNGSGVEMQLQDTSGTHFDGLIETANELVEQLKLQP-EVASASVSL 714 + A+ LG +G + +L D +G D L + N+L+ P + S + Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 715 QSAIPQLHLTVDEAKAMAIGVNVGDIYSTIKTLTDSSTVNDFNLFGRVYRVKIQAEESYR 774 Q L VD+ KA A+GV++ DI TI T + VNDF GRV ++ +QA+ +R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 775 QFPHQIKDYYVRSSNGAMVPIGVLAKYDYTVGPSSVTHYNLFSSASINVTPATGYATGDV 834 P + YVRS+NG MVP + G + YN S I A G ++GD Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 835 IQAIERVATPILPDEFKYEWTGITYQEVQSANQTGIAIGLALLFVFLFLAALYESWSIPV 894 + +E +A+ LP Y+WTG++YQE S NQ + ++ + VFL LAALYESWSIPV Sbjct: 840 MALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPV 898 Query: 895 AVLLIAPIALLGAAVTTLISGMQSNLFFQVAFIALIGMAAKNAILIVEFANQLH-QQGRT 953 +V+L+ P+ ++G + + +++++F V + IG++AKNAILIVEFA L ++G+ Sbjct: 899 SVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKG 958 Query: 954 RISAALEAATMRFRPILMTSMAFILGVLPLVLSEGPGAVSRQSISLPILGGMVLATTIGI 1013 + A L A MR RPILMTS+AFILGVLPL +S G G+ ++ ++ + ++GGMV AT + I Sbjct: 959 VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAI 1018 Query: 1014 VFVPLFFV 1021 FVP+FFV Sbjct: 1019 FFVPVFFV 1026 Score = 110 bits (276), Expect = 1e-26 Identities = 74/513 (14%), Positives = 184/513 (35%), Gaps = 37/513 (7%) Query: 5 FINRPIFASVISIVIVLLGVIAMFKLPVDQYPYITPPQVTISASYPGASSTTAAESVATP 64 + +I +IV V+ +LP P P ++ + V Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 65 LEQ-----EVNGVPNMIYMSSKSTNSGSTSVTITF------DVGTNADLAAVDVQNSAQQ 113 + E V ++ ++ S + + + + F + + +A V + A+ Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKM 652 Query: 114 ASGGLP--------IDVQTEGVTVSKDASVELLKLALTSNDERFDEIYLSNYATINIESA 165 G + + E T + EL+ A +D L+ + A Sbjct: 653 ELGKIRDGFVIPFNMPAIVELGTATG-FDFELIDQAGLGHDA------LTQARNQLLGMA 705 Query: 166 LKRIPGVGRTRNTGS-RSYAMRIWLKPDAMAGYSLTTTDVINAIKAQNKESPAGTIGTQP 224 + + R G + ++ + + ++ +D+ I + + Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 225 NNDDISLTLPISVAGRLSSVQAFNEIIVRANPDGSIIRLRDIAGVELGSSAYTLQSQLNG 284 + + A + +++ VR + +G ++ + L + NG Sbjct: 766 RVKKLYVQAD---AKFRMLPEDVDKLYVR-SANGEMVPFSAFTTSHWVYGSPRL-ERYNG 820 Query: 285 ENATILQVYLLPGANALEVTHKVKQAMAELSQKFPQGMKWEVFYDASIFIQESIDEVIHT 344 + +Q PG ++ + ++ ++L P G+ + S + S ++ Sbjct: 821 LPSMEIQGEAAPGTSSGDAMALMENLASKL----PAGI-GYDWTGMSYQERLSGNQAPAL 875 Query: 345 LIEALVLVVLVVYLFLQNVRATLIPAIAVPVSLIGTLAAMLAFGFTINTVSLLALVLAIG 404 + + V+V L + ++ + + VP+ ++G L A F + ++ L+ IG Sbjct: 876 VAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIG 935 Query: 405 IVVDDAIVVVENVERLIHEKGMSAIDATRIAMKELSGALVATSLVLCAVFVPVSFLAGIT 464 + +AI++VE + L+ ++G ++AT +A++ ++ TSL +P++ G Sbjct: 936 LSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAG 995 Query: 465 GIMYREFAVAITVAVLISTLVALTLSPALCALL 497 + + ++ +TL+A+ P ++ Sbjct: 996 SGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028 Score = 74.9 bits (184), Expect = 1e-15 Identities = 79/501 (15%), Positives = 173/501 (34%), Gaps = 37/501 (7%) Query: 539 LAFAIMFGGTYFIMSHLPSSFMPDEDQGRFFIDMTLPDGSTVNRTEAILKKAEQYVRANP 598 LA +M G I+ LP + P + P + + + EQ + Sbjct: 15 LAIILMMAGALAILQ-LPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIEQNMNGID 73 Query: 599 AVAYSFTLAGENRRSGANQANGQFEVVLKP-WAEREASHATVQSVMKAIDKDLKNVLEAE 657 + Y ++ + +G+ F+ P A+ + +Q + ++++ Sbjct: 74 NLMY---MSSTSDSAGSVTITLTFQSGTDPDIAQVQVQ-NKLQLATPLLPQEVQ------ 123 Query: 658 FNLYLPSAVPGLGNGSGVEMQLQDTSGTHFDGLIETANELVEQLKLQPEVAS--ASVSLQ 715 + + S M S + ++ + +K + V L Sbjct: 124 -----QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLF 178 Query: 716 SAIPQLHLTVDEAKAMAIGVNVGDIYSTIKTLTDSSTVNDFNLFGRVYRVKIQA---EES 772 A + + +D + D+ + +K D + ++ A ++ Sbjct: 179 GAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 773 YRQFPHQIKDYYVRSS-NGAMVPIGVLAK-YDYTVGPSSVTHYNLFSSASINVTPATGYA 830 + P + +R + +G++V + +A+ + + N +A + + ATG Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 831 TGDVIQAI-ERVAT--PILPDEFKYEWTGITYQEVQSANQT-----GIAIGLALLFVFLF 882 D +AI ++A P P K + T VQ + AI L L ++LF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 883 LAALYESWSIPVAVLLIAPIALLGAAVTTLISGMQSNLFFQVAFIALIGMAAKNAILIVE 942 L ++ + + P+ LLG G N + IG+ +AI++VE Sbjct: 359 L----QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 943 FANQLHQQGRTRISAALEAATMRFR-PILMTSMAFILGVLPLVLSEGPGAVSRQSISLPI 1001 ++ + + A E + + + ++ +M +P+ G + S+ I Sbjct: 415 NVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 1002 LGGMVLATTIGIVFVPLFFVT 1022 + M L+ + ++ P T Sbjct: 475 VSAMALSVLVALILTPALCAT 495
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 133 bits (335), Expect = 7e-36 Identities = 85/390 (21%), Positives = 173/390 (44%), Gaps = 15/390 (3%) Query: 51 LDTTIANVALPHMQGSMGATQDQISWVLTSYIVAAAIFMPLTGFLTARLGRKRVFMWAVV 110 L+ + NV+LP + +WV T++++ +I + G L+ +LG KR+ ++ ++ Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 111 GFTIASMLCGAAQNLEQIVLF-RLLQGVFGASLVPLSQSVLLDSYPPERHGSAMALWGVG 169 S++ + +++ R +QG A+ L V+ P E G A L G Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 170 VMVGPILGPSLGGWLTEYYNWRWVFYINLPFGLLAWFGLAAYVKETPLDHSRKFDLLGFA 229 V +G +GP++GG + Y +W + + +P + + + + FD+ G Sbjct: 148 VAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGII 205 Query: 230 MLSLAIGALQMLLDRGESLDWFSSREIVIEAIIAGMAFYLFVAHIFTHKHPFIEPGLFKD 289 ++S+ I + F++ + I++ ++F +FV HI PF++PGL K+ Sbjct: 206 LMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKN 255 Query: 290 RNFSVGLIFIFIIGIILLATMALLPPFMQNLLGYPVIDVGY-LLAPRGVGTMIAMMTVGK 348 F +G++ II + ++++P M+++ ++G ++ P + +I G Sbjct: 256 IPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGI 315 Query: 349 LAGKVDVRYQIFLGLMLTILSLWEMTGFNTNITGWDIVRTGVIQGLGLGFIFVPLSTITF 408 L + Y + +G+ +S F T W + V GL F +STI Sbjct: 316 LVDRRGPLYVLNIGVTFLSVSFLTA-SFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVS 374 Query: 409 ATLAAKYRNEGTALFSLMRNIGSSIGISVV 438 ++L + G +L + + GI++V Sbjct: 375 SSLKQQEAGAGMSLLNFTSFLSEGTGIAIV 404
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 87.2 bits (216), Expect = 4e-21 Identities = 44/286 (15%), Positives = 96/286 (33%), Gaps = 26/286 (9%) Query: 71 VENQRVEKGQVLFRLDDAMFKVMVDKASAKLAQVKTDLAVLKASYHEKQAEITLAETKLT 130 V + V + L + + ++ + L + + + + A + + + +++L Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRL- 237 Query: 131 FAEKEQKRQENLIGKHFV--SESQLEDARQNTDIARQNIQTLQKDLHRIAESLGGSP-DF 187 + + I KH V E++ +A + + ++ ++ ++ E F Sbjct: 238 -DDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF 296 Query: 188 PIEQHPSYLEALAQLNE-------AKLDLSRVEIKAPVSGVVSQLP--KLGQYVNVGAIA 238 E + + + I+APVS V QL G V Sbjct: 297 KNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL 356 Query: 239 LALV-ADHALWIEANFTETDLTHVKPGQKVNIHIDTFPDNRW---QGTVESLSPATGAEF 294 + +V D L + A D+ + GQ I ++ FP R+ G V++++ Sbjct: 357 MVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA---- 412 Query: 295 SLIPAQNATGNWVKIAQRVPVRIAIDTVLPEAPLRAGLSAVVDIDT 340 G + + PL +G++ +I T Sbjct: 413 ---IEDQRLGLVFNVIISIEENCLST-GNKNIPLSSGMAVTAEIKT 454 Score = 56.8 bits (137), Expect = 5e-11 Identities = 22/138 (15%), Positives = 43/138 (31%), Gaps = 12/138 (8%) Query: 50 VKADKVPVSAQVAGNVDSLYVVENQRVEKGQVLFRLDDAMFKVMVDKASAKLAQVKTDLA 109 + V + V E + V KG VL +L + K + L Q + + Sbjct: 92 HSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQT 151 Query: 110 VLKASY----HEKQAEITLAETK--LTFAEKEQKRQENLIGKHFVSESQLEDARQNTDIA 163 + K E+ L + +E+E R +LI + Q + Sbjct: 152 RYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLI------KEQFSTWQNQKYQK 205 Query: 164 RQNIQTLQKDLHRIAESL 181 N+ + + + + Sbjct: 206 ELNLDKKRAERLTVLARI 223
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 36.1 bits (83), Expect = 2e-04 Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 7/53 (13%) Query: 95 LINSLISKISQLTQGTEAFSSTLADFGLQLQSTPDVCTLNQLVGGVIDEMQNL 147 LIN L+ ++ L +FS L G L +T + GV +++QNL Sbjct: 187 LINQLVDTVASLNNNVNSFSQQLNTLGSVLSNTKH-------LNGVGNKLQNL 232
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.049 Identities = 10/31 (32%), Positives = 15/31 (48%), Gaps = 1/31 (3%) Query: 39 KWDKEVEVLIVGSGFAGLAAGIEAIRKGAKD 69 K ++ VL++ S I+A KGA D Sbjct: 71 KARPDLPVLVM-SAQNTFMTAIKASEKGAYD 100
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 29.9 bits (67), Expect = 0.014 Identities = 22/140 (15%), Positives = 42/140 (30%), Gaps = 24/140 (17%) Query: 4 ALVLTQEDSRINARVAQISETDLPEGEVLVDVAYSSLNYKDGLAVTGTGKIIRQFPMVPG 63 AL++T +N I++ D+ +VLV+ + + DGL + G Sbjct: 320 ALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNL--------------G 365 Query: 64 IDFAGVVNQSNDPRYQAGDQVILTGWGVGENHWGGMAQKARVKADWLVSMPQNCDPAKAM 123 I +A + Q +G + G S+ + Sbjct: 366 IQWAN--------KNAGMTQFTNSGLPISTAIAGANQYNK--DGTVSSSLASALSSFNGI 415 Query: 124 MIGTAGLTAMLCVQALEQAG 143 G + + AL + Sbjct: 416 AAGFYQGNWAMLLTALSSST 435
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 71.9 bits (176), Expect = 1e-16 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 2/92 (2%) Query: 142 ELALGMNVQFRTGSSELESHFLPQLDNVAKVMKRSSESN--LELKGYADRRGDLAYNQAL 199 L +V F + L+ LD + + + + + GY DR G AYNQ L Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGL 273 Query: 200 SEQRLLEVRGYLIKQGVAPERITTQAFGARMP 231 SE+R V YLI +G+ ++I+ + G P Sbjct: 274 SERRAQSVVDYLISKGIPADKISARGMGESNP 305
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.3 bits (154), Expect = 7e-14 Identities = 29/134 (21%), Positives = 54/134 (40%), Gaps = 5/134 (3%) Query: 3 RIAIVEDEAAIRENYKDVLQQHGYSVQTYADRPSAMLAFNTRLPDLAIIDIGLGNEIDGG 62 I + +D+AAIR L + GY V+ ++ + DL + D+ + +E Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE--NA 62 Query: 63 FMLCQSLRAMSNTLPIIFLTARDSDFDTVCGLRLGADDYLSKEVSFPH---LTARLAALF 119 F L ++ LP++ ++A+++ + GA DYL K + R A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 120 RRSELATSQTPQEN 133 +R Q+ Sbjct: 123 KRRPSKLEDDSQDG 136
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 42.4 bits (100), Expect = 3e-06 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 11/81 (13%) Query: 191 AAKRAGFVDVAFLFEPLAAGMDYEASLSADQTVLVVDVGGGTTDCSVVKMGPKHQASFDR 250 +A+ AG +V + EP+AA + +S +VVD+GGGTT+ +V+ + Sbjct: 129 SAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN--------- 179 Query: 251 SADCLGHSGQRIGGNDLDIAL 271 + S RIGG+ D A+ Sbjct: 180 --GVVYSSSVRIGGDRFDEAI 198
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 29.3 bits (66), Expect = 0.039 Identities = 16/36 (44%), Positives = 24/36 (66%) Query: 137 NIVIDIGGGSTEVVLGQKNTPTHLSSLRCGCVSFNE 172 ++V+DIGGG+TEV + N + SS+R G F+E Sbjct: 161 SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDE 196
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 28.3 bits (63), Expect = 0.034 Identities = 16/90 (17%), Positives = 34/90 (37%), Gaps = 16/90 (17%) Query: 59 RFRKEIEYPANLNLKTLCLIAIAGGC-----------LGAAILLSTSEQVFANLV----- 102 R ++ + YP L + + +++I + A+ LST + + Sbjct: 168 RIQQAMIYPCVLTVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFG 227 Query: 103 PWLILLATLAFIGGPWLLKKRLANASITRM 132 PW++L F+ +L++ S R Sbjct: 228 PWMLLALLAGFMAFRVMLRQEKRRVSFHRR 257
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.5 bits (79), Expect = 6e-05 Identities = 25/111 (22%), Positives = 35/111 (31%), Gaps = 24/111 (21%) Query: 33 LKQYLDAPKRSDEI-YLAESEGVVFGLISLIFFDYFPSQQKICRITA------------L 79 KQY D ++ Y+ E F Y+ I RI + Sbjct: 47 FKQYEDD---DMDVSYVEEEGKAAFL--------YYLENNCIGRIKIRSNWNGYALIEDI 95 Query: 80 VVTEASRGLGVGTQLIDFAKDRASERGCHQLEVTTSMRREQTQVYYESIGF 130 V + R GVGT L+ A + A E L + T +Y F Sbjct: 96 AVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 843 bits (2179), Expect = 0.0 Identities = 324/1039 (31%), Positives = 555/1039 (53%), Gaps = 38/1039 (3%) Query: 3 LTDLSVKRPVFASVISLLLVAFGLVAFDKLPLREYPNIDPPIVSIETNYRGASAAVVESR 62 + + ++RP+FA V++++L+ G +A +LP+ +YP I PP VS+ NY GA A V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 ITQLIEDRISGVEGIRHVSSSS-SDGRSQVTLEFDISRNIEDAANDVRDRISGLLDNLPE 121 +TQ+IE ++G++ + ++SS+S S G +TL F + + A V++++ LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 EADPPEVQKANGGDEVIMWLNLVSD--QMTTLELTDYTRRYLSDRLSVVDGVSMIRIGGG 179 E + +M VSD T +++DY + D LS ++GV +++ G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 KVYAMRVWLDRQALASRSLTVADVEAALRAENVELPAGSL------ESKERHFTVRLERS 233 + YAMR+WLD L LT DV L+ +N ++ AG L ++ + ++ + Sbjct: 181 Q-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 YRTAEDFANLVISQGEDGYLVKLGDVAKVEIGSEEERIMFRGNKEAMIGLGVSKQSTANT 293 ++ E+F + + DG +V+L DVA+VE+G E ++ R N + GLG+ + AN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 LEVARAVNALVDKINPTLPAGMSIKRSYDSSVFIEASIKEVYQTLFTAMVLVIIVIYLFL 353 L+ A+A+ A + ++ P P GM + YD++ F++ SI EV +TLF A++LV +V+YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 GSVRAMLIPAITVPVSLLGTFIVLYALGYTINLLTLLAMILAIGMVVDDAIVMLENIHRR 413 ++RA LIP I VPV LLGTF +L A GY+IN LT+ M+LAIG++VDDAIV++EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 I-EEGDSPLKAAFLGAREVAFAVIATTLVLVAVFMPITFLEGDLGKLFKEFAVAMSAAVI 472 + E+ P +A ++ A++ +VL AVF+P+ F G G ++++F++ + +A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 FSSIVALTLSPMMCSKLLKPASQD---------SWLVRKVDSIMTGISRGYQSSLEKAMA 523 S +VAL L+P +C+ LLKP S + W D + + L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKIL----G 535 Query: 524 RPVLMSILVLIALGSSVLLAQKVPQEFAPQEDRGSLFLMVNGPQGASYEYIESYMNEVEN 583 ++ + + V+L ++P F P+ED+G M+ P GA+ E + +++V + Sbjct: 536 STGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTD 595 Query: 584 RLMPLVDSGDIKRLLIRAPRGFGRAADFSNGMAIIVLEDWGQRRPMKE----VIGDINKR 639 + + +++ + F A + GMA + L+ W +R + VI Sbjct: 596 YYLK-NEKANVESVFTVNGFSFSGQAQ-NAGMAFVSLKPWEERNGDENSAEAVIHRAKME 653 Query: 640 LADL--AGVQAFPVMRQA-FGRGVGKPVQFV-IGGPSYEELARWRDIMMEKAAENP-KLL 694 L + V F + G G + + G ++ L + R+ ++ AA++P L+ Sbjct: 654 LGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLV 713 Query: 695 GLDHDYKETKPQLRVVIDRDRAASLGVSISNIGRTLESMLGSRLVTTFMRDGEEYDVIVE 754 + + E Q ++ +D+++A +LGVS+S+I +T+ + LG V F+ G + V+ Sbjct: 714 SVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQ 773 Query: 755 GERSNQNTAADLQNIYVRSERTKELIPLSNLVTVEEFADASSLNRYNRMRAITIEASLAD 814 + + D+ +YVRS E++P S T + L RYN + ++ I+ A Sbjct: 774 ADAKFRMLPEDVDKLYVRS-ANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAP 832 Query: 815 GYSLGEALDYLNQVARAYLPAEAVISYKGQSLDYQESGSSMYFVFLLALGIVFLVLAAQF 874 G S G+A+ + +A LPA + G S + SG+ + ++ +VFL LAA + Sbjct: 833 GTSSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALY 891 Query: 875 ESYIHPMVIMLTVPLATVGALIGLWFTGQSLNIYSQIGIIMLVGLAAKNGILIVEFANQL 934 ES+ P+ +ML VPL VG L+ Q ++Y +G++ +GL+AKN ILIVEFA L Sbjct: 892 ESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDL 951 Query: 935 RDK-GVDFDRAIIQASCQRLRPILMTGITTAAGAVPLVLAAGAGAETRFVIGVVVLSGIM 993 +K G A + A RLRPILMT + G +PL ++ GAG+ + +G+ V+ G++ Sbjct: 952 MEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMV 1011 Query: 994 LATLFTIFVIPTAYGLFAR 1012 ATL IF +P + + R Sbjct: 1012 SATLLAIFFVPVFFVVIRR 1030 Score = 88.4 bits (219), Expect = 8e-20 Identities = 51/327 (15%), Positives = 125/327 (38%), Gaps = 19/327 (5%) Query: 706 QLRVVIDRDRAASLGVSISNIGRTLES----MLGSRLVTTFMRDGEEYDVIVEGERSNQN 761 +R+ +D D ++ ++ L+ + +L T G++ + + + + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQ-TRFK 241 Query: 762 TAADLQNIYVRSERTKELIPLSNLVTVEE-FADASSLNRYNRMRAITIEASLADGYSLGE 820 + + +R ++ L ++ VE + + + R N A + LA G Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATG---AN 298 Query: 821 ALDYLNQVA------RAYLPA--EAVISYKGQSLDYQESGSSMYFVFLLALGIVFLVLAA 872 ALD + + + P + + Y + Q S + A+ +VFLV+ Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYD-TTPFVQLSIHEVVKTLFEAIMLVFLVMYL 357 Query: 873 QFESYIHPMVIMLTVPLATVGALIGLWFTGQSLNIYSQIGIIMLVGLAAKNGILIVE-FA 931 ++ ++ + VP+ +G L G S+N + G+++ +GL + I++VE Sbjct: 358 FLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVE 417 Query: 932 NQLRDKGVDFDRAIIQASCQRLRPILMTGITTAAGAVPLVLAAGAGAETRFVIGVVVLSG 991 + + + A ++ Q ++ + +A +P+ G+ + ++S Sbjct: 418 RVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSA 477 Query: 992 IMLATLFTIFVIPTAYGLFARNSGSPE 1018 + L+ L + + P + + Sbjct: 478 MALSVLVALILTPALCATLLKPVSAEH 504
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.3 bits (89), Expect = 4e-05 Identities = 23/116 (19%), Positives = 40/116 (34%), Gaps = 6/116 (5%) Query: 37 VVIATAAMAPVRDEVEAIGTNKAY-ESVTITPKVTDVVTSLKFDDGDIVKKGDLLVQLQN 95 + + + V A G S I P +V + +G+ V+KGD+L++L Sbjct: 70 IAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTA 129 Query: 96 AEQIAKVKVAQVKVSDNQRELARISSLVTSRTVAELERDRLQTLIDTTRAELEQAQ 151 A Q + + E R L S +E ++L L + Sbjct: 130 LGAEADTLKTQSSLLQARLEQTRYQILSRS-----IELNKLPELKLPDEPYFQNVS 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.010 Identities = 9/16 (56%), Positives = 14/16 (87%) Query: 38 LVGESGSGRSLLARAI 53 + GESG+G+ L+ARA+ Sbjct: 165 ITGESGTGKELVARAL 180
>ENTEROTOXINA#Heat-labile enterotoxin A chain signature. Length = 258 Score = 29.6 bits (66), Expect = 0.025 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 15/71 (21%) Query: 275 NFFTIRDVLGHYDPET----------VRYFLLSGHYRSQINYSEENLKQARAALERLYTA 324 N F + DVLG Y P + Y + G YR +E L + R +R Y Sbjct: 111 NMFNVNDVLGVYSPHPYEQEVSALGGIPYSQIYGWYRVNFGVIDERLHRNREYRDRYYR- 169 Query: 325 IKDVDLTVAPA 335 +L +APA Sbjct: 170 ----NLNIAPA 176
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 28.6 bits (64), Expect = 0.034 Identities = 10/44 (22%), Positives = 19/44 (43%), Gaps = 1/44 (2%) Query: 217 ALVDAGDEMAIAAFDRYMDRLARSLAHVINMLDP-DAIVLGGGM 259 A GD+ A A + + R+ +++ + D IV G+ Sbjct: 289 AAFKNGDKRAQLALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGI 332
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 38.2 bits (89), Expect = 4e-05 Identities = 50/247 (20%), Positives = 82/247 (33%), Gaps = 71/247 (28%) Query: 12 ITVLLTGA----DSQLSKALLR------VLAKAANRFDGRV--FRVHALSHA-----QLD 54 + L+TGA +SK LL + + +D + R+ L+ ++D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 55 IADKQSVAAAFARFKPDWVINCAAYNAVDRAETAAEEAY-RVNSLGPELL---ARECALT 110 +AD++ + FA + V AV R AY N G + R + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAV-RYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 111 GARLVHISSDYVFSGEPAGAAVQALNQNGLTDSRLIESGLTER--GLTESATPAPLSVYG 168 L++ SS V+ GL + T+ + P+S+Y Sbjct: 120 --HLLYASSSSVY-------------------------GLNRKMPFSTDDSVDHPVSLYA 152 Query: 169 QSKLAGEQAVLCILAERAIVIRTAWL-----YGVDG------HNFVKTMLRLMATMPEGQ 217 +K A E ++ + L YG G F K ML EG+ Sbjct: 153 ATKKANE--LMAHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAML-------EGK 203 Query: 218 PLTVIND 224 + V N Sbjct: 204 SIDVYNY 210
>PF06340#Vibrio cholerae toxin co-regulated pilus biosynthesis protein F (TcpF) Length = 338 Score = 29.6 bits (66), Expect = 0.041 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 18/83 (21%) Query: 216 YSSFKTKLADTQISADEQARLLAQAKANIESDVKPAYRLFIDYFTALQAKAGTDDGYWAL 275 YSS ++ A T+ D ARLLA +++ +L+ID++ A T D W + Sbjct: 83 YSSTESDGAKTRTKEDFSARLLAGDYDSLQ-------KLYIDFYLA----QTTFD--WEI 129 Query: 276 PNGD-----VAYEQLLKFFTTTN 293 P D V Y K T N Sbjct: 130 PTRDQIETLVNYANEGKLSTALN 152
>PF07520#Virulence protein SrfB Length = 1041 Score = 30.3 bits (68), Expect = 0.028 Identities = 25/152 (16%), Positives = 41/152 (26%), Gaps = 26/152 (17%) Query: 520 IPESLEGSLMLVSQVLHQCGVPLAR-ILKRLESERRNHYQFLHGFFSGTETDF---TLES 575 I + ++ Q + VPLA IL E + + E Sbjct: 676 IGGQEQQTVQRRRQFSIRVLVPLAEAILSACEDAEEADR--IDIPVADVLGLVPTPVGEE 733 Query: 576 LHAVLLHRGADAVGKQVADI-----------DWELLRVELRAIRRSGQEIEHPASDWIFR 624 + V ++ D W L + L A R I + Sbjct: 734 GDEEGHEDASPQVTDEILDYLEKPATQLGAEGWRLADMVLSASREDLDAIAREVFQKVLG 793 Query: 625 A---------GDILLIVGKPRRLEKAEAKLLH 647 D++L+ G+P RL A + Sbjct: 794 NMCEVIDHLGCDVVLLTGRPSRLPAVRAIVEE 825
>PF06580#Sensor histidine kinase Length = 349 Score = 32.5 bits (74), Expect = 0.003 Identities = 20/105 (19%), Positives = 34/105 (32%), Gaps = 26/105 (24%) Query: 327 LISNAIRY----TEPGGKITVQWRSVATGGLFSVTDTGEGIAPQHINRLTERFYRVDSAR 382 L+ N I++ GGKI ++ V +TG Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 383 SRQTGGSGLGLAIVKHALSHHHSE---LNISSELGKGSTFSFVIP 424 +G GL V+ L + + +S + GK + +IP Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.4 bits (227), Expect = 2e-23 Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 4/130 (3%) Query: 3 ARILIVEDELAIREMLTFVMEQHGFTTSAAEDFDSAIALLKEPYPDLILLDWMFPGGSGI 62 A IL+ +D+ AIR +L + + G+ + + + DL++ D + P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 QLAKRLKQDEFTRQIPIIMLTARGEEEDKVKGLEVGADDYITKPFSPKELVARIKAVL-- 120 L R+K+ +P+++++A+ +K E GA DY+ KPF EL+ I L Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 121 RRSAPTRLEE 130 + P++LE+ Sbjct: 122 PKRRPSKLED 131
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 81.4 bits (201), Expect = 1e-19 Identities = 78/335 (23%), Positives = 127/335 (37%), Gaps = 33/335 (9%) Query: 7 KTLLASALASATLASAYAAEPLTVYGKLNV---TAQSNDEKGDST------TTIQSNASR 57 K+L+A LA+ +A A +T+YG + T++S G T I S+ Sbjct: 3 KSLIALTLAALPVA---AMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSK 59 Query: 58 FGVKGDFELSSSLEAFYTVEYEVDTGAATSDNFKARNQFVGLKGAFGSFSVGRNDTLLKI 117 G KG +L + L+A + VE + A T + R F+GLKG FG VGR +++LK Sbjct: 60 IGFKGQEDLGNGLKAIWQVEQKASI-AGTDSGWGNRQSFIGLKGGFGKLRVGRLNSVLK- 117 Query: 118 SQGNVDQFNDLSGDL--KSLFKGENRLGQTATYLSPSIGGFVFGATYAAEGDADQQAQDG 175 G+++ ++ S L + + E RL + Y SP G YA +A + + Sbjct: 118 DTGDINPWDSKSDYLGVNKIAEPEARL-ISVRYDSPEFAGLSGSVQYALNDNAGRHNSES 176 Query: 176 FSLAAMYGDAKLKKSPFYAAIAYDSDVKGYEILRASVQGKIADLTLGGMYQQQEQTYKNA 235 + Y + A + + I + + ++ +Y ++A Sbjct: 177 YHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASVAVQQQDA 236 Query: 236 LPV----NTDSVNGYLFSAAYDINAVTLKAQY----------QDMEDLGDSWSVGADYSL 281 V + +S + AY VT + Y + + D VGA+Y Sbjct: 237 KLVEENYSHNSQTEVAATLAYRFGNVTPRVSYAHGFKGSFDATNYNNDYDQVVVGAEYDF 296 Query: 282 GKPTKVFAFYT--NRSMEASNDDDKYIAVGLEHKF 314 K T S VGL HKF Sbjct: 297 SKRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>SECA#SecA protein signature. Length = 901 Score = 30.2 bits (68), Expect = 0.010 Identities = 10/41 (24%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Query: 81 ESLEEKVALIEDEENRKLAKKEKDALKD-EIITSLLPRAFS 120 ++E ++ + DEE + + + L+ E++ +L+P AF+ Sbjct: 29 NAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFA 69
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.4 bits (133), Expect = 9e-12 Identities = 20/134 (14%), Positives = 45/134 (33%), Gaps = 4/134 (2%) Query: 13 DKRQQLISTAFKLFYFQSVHGVGINQILQESAIAKKTLYHHFASKDELVEAVVLYRDHVF 72 + RQ ++ A +LF Q V + +I + + + + +Y HF K +L + + Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 73 YQWLSER-VQAAETGKAGIRALFMALDDWFNQRVPQLCEFRGCFFINASAEFTDASHPVH 131 + E + + +R + + + + + F EF V Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTE-ERRRLLMEIIF--HKCEFVGEMAVVQ 127 Query: 132 RLCAEHKQRVADLM 145 + D + Sbjct: 128 QAQRNLCLESYDRI 141
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 140 bits (355), Expect = 1e-44 Identities = 67/132 (50%), Positives = 89/132 (67%), Gaps = 2/132 (1%) Query: 25 KAAQENIRLGNEFLAQNKTQEGVKTTASGLQYQVLKQGTGTVHPKASDTVTVHYHGTLID 84 K A+EN G+ FL+ NK++ G+ SGLQY+++ GTG P SDTVTV Y GTLID Sbjct: 99 KKAEENKAKGDAFLSANKSKPGIVVLPSGLQYKIIDAGTGA-KPGKSDTVTVEYTGTLID 157 Query: 85 GTVFDSSVERGEPIAFPLNRVIPGWTEGVQLMVEGDKYRFFIPSELAYGNRST-GKIGGG 143 GTVFDS+ + G+P F +++VIPGWTE +QLM G + F+P++LAYG RS G IG Sbjct: 158 GTVFDSTEKAGKPATFQVSQVIPGWTEALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPN 217 Query: 144 SVLIFDVELLKV 155 LIF + L+ V Sbjct: 218 ETLIFKIHLISV 229
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 45.9 bits (108), Expect = 8e-07 Identities = 40/211 (18%), Positives = 77/211 (36%), Gaps = 19/211 (9%) Query: 542 WEIDADNGDILNAMHEGLGHGEGTTPPANKAPIANAGTDVTVTGTLDVTLNGSASRDPEN 601 ++D + + + + G+ T NK P A +D +V ++ +G+ S+D + Sbjct: 744 HKVDGNGNYVYDVVFHGMNTDTNTDVHVNKEPKAVIKSDSSVIVEEEINFDGTESKDEDG 803 Query: 602 AALSYQWSQVSGPSLSITNADMANAVVQLSATASDVVYVFSLRVTDPEGLSSTDTVTLTH 661 +Y+W G ++ A A + + T Y L VTD G +T++ + Sbjct: 804 EIKAYEWDFGDG-----EKSNEAKATHKYNKTGE---YEVKLTVTDNNGGINTESKKIKV 855 Query: 662 KAETVNQAPVV--TVPASVTVEAGQSVSINATAT---DADGDSLTYAWTVPS----GVAA 712 + V+ + P + +A Q N + S Y + V + Sbjct: 856 VED--KPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKGNVKITL 913 Query: 713 SGQNSATLVVTAPAVTQSTQYSLSVLVSDGS 743 + NS + T Y L +DG+ Sbjct: 914 NNLNSVGITWTLYKEGDLNNYVLYATGNDGT 944
>FLAGELLIN#Flagellin signature. Length = 507 Score = 31.9 bits (72), Expect = 0.006 Identities = 14/87 (16%), Positives = 33/87 (37%), Gaps = 4/87 (4%) Query: 282 QLASAMEEMSSTIAEVAQNTQLTSTSINTAYDLCLKSSANMKANTQKVEQLAKSVADAAN 341 +A+ + + ++N + T + + N Q+V +L+ + N Sbjct: 48 AIANRFTSNIKGLTQASRNANDGISIAQTTE----GALNEINNNLQRVRELSVQATNGTN 103 Query: 342 NAHQLNKEAERVASAMGEIDSIAEQTN 368 + L + + + EID ++ QT Sbjct: 104 SDSDLKSIQDEIQQRLEEIDRVSNQTQ 130
>SECA#SecA protein signature. Length = 901 Score = 31.4 bits (71), Expect = 0.007 Identities = 37/173 (21%), Positives = 67/173 (38%), Gaps = 42/173 (24%) Query: 220 SQVVYPVEQRRKRELLSELIGK-KNWQQVLVFTATRDAADTLVKELNLDGIPSEVVHGEK 278 +VY E + + ++ ++ + Q VLV T + + ++ + EL GI V++ Sbjct: 424 PDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLN--- 480 Query: 279 AQGSRRRALREFMSGKV-RVLVATEVAARGLDI---------------PSLEYVVNFDLP 322 A+ A +G V +AT +A RG DI P+ E + Sbjct: 481 AKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKAD 540 Query: 323 FLAED---------YV-----H---RI-----GRTGRAGKSGVAISFVSREEE 353 + ++ H RI GR+GR G +G + ++S E+ Sbjct: 541 WQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDA 593 Score = 29.8 bits (67), Expect = 0.022 Identities = 47/256 (18%), Positives = 95/256 (37%), Gaps = 41/256 (16%) Query: 23 KMTPIQQQAIPAIRRGQDVLASAQTGTGKTAAFALPI-LQKMAENPSETLKSNARVLILT 81 M Q + + + +A +TG GKT LP L + V ++T Sbjct: 80 GMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKG---------VHVVT 130 Query: 82 PTRELAAQVADNVEAYSKYLNFSVLTIYGGVKVETQAQKLKR---GADIIVATPGRLLEH 138 LA + A+N ++L +V G+ + KR ADI T Sbjct: 131 VNDYLAQRDAENNRPLFEFLGLTV-----GINLPGMPAPAKREAYAADITYGTNNEYGFD 185 Query: 139 LTACNLSLSSID-------FLVLDEADRMLDMGFNADIQKILQAVNKKRQNLLFSATFSS 191 N++ S + + ++DE D +L +++ R L+ S Sbjct: 186 YLRDNMAFSPEERVQRKLHYALVDEVDSIL--------------IDEARTPLIISGPAED 231 Query: 192 AVKKLANEMMVKPQVISADKQNTTADTVSQVVYPVEQRRKRELLSELIGKKNWQQVLVFT 251 + + + P +I +K+++ + + V+++ ++ L+E G +++LV Sbjct: 232 SSEMYKRVNKIIPHLIRQEKEDSETFQG-EGHFSVDEKSRQVNLTER-GLVLIEELLVKE 289 Query: 252 ATRDAADTLVKELNLD 267 D ++L N+ Sbjct: 290 GIMDEGESLYSPANIM 305
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 32.5 bits (74), Expect = 0.001 Identities = 14/101 (13%), Positives = 37/101 (36%), Gaps = 3/101 (2%) Query: 104 VSYDVTLN--RYNYSGESDLGYFEVTAGVEFSGFRV-AYWYTNDYGGSDLDYHYGEINYS 160 ++Y+ + N + G S Y + +G+ +R+ + + + Sbjct: 187 LNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHI 246 Query: 161 YEFVENWSLDLHYGYNVGDALDDGEGFDSYSDYSVGVSTEF 201 ++E + L +GD G+ FD + ++++ Sbjct: 247 NTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDD 287
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 30.0 bits (67), Expect = 0.021 Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 8/82 (9%) Query: 2 STTAPGSVA---NTGVNAQDAAAKKSQSKPRLMSLDALRGFDMFWILGGEALFGALLILT 58 + A G+V+ G+ + A K ++ + A +GF+ + L+ +LL Sbjct: 50 TGAAVGTVSGLLGWGLKQAEEANKTPDKPDKVWRIQAGKGFNE-FPNKEYDLYKSLLSSK 108 Query: 59 GWAGWQWGDTQMHH----SEWN 76 GW WG+ H+ +WN Sbjct: 109 IDGGWDWGNAARHYWVKDGQWN 130
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 29.7 bits (67), Expect = 0.019 Identities = 13/26 (50%), Positives = 18/26 (69%) Query: 334 PAEFLGIAKNVGRLAVGQRADLVLLD 359 PA G++ +G L VG+RADLVL + Sbjct: 413 PAIAHGLSHEIGSLEVGKRADLVLWN 438
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 30.5 bits (68), Expect = 0.035 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Query: 5 IAATAILLALGLTACSDVP-KTEAVPSSSTAEQAKPNQLTQAQLQ 48 +AAT I AL LT D P T+ +++ AE A +QLTQ + Sbjct: 248 LAATGIAQALALTPEPDDPTTTDPDQAANAAESATKDQLTQEAFK 292
>PF05307#Bundlin Length = 193 Score = 30.5 bits (68), Expect = 0.006 Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 11/143 (7%) Query: 17 QRGLSLVELMVAMVIGLFLTAGVFTMFSMSSSNVTTTSQFNQLQENGRIALAILERDITQ 76 ++GLSL+E + + + +TAGV MF S++ + SQ N + E AI I Q Sbjct: 11 EKGLSLIESAMVLALAATVTAGV--MFYYQSASDSNKSQ-NAISEVMSATSAINGLYIGQ 67 Query: 77 LAFMG---DMTGTDFIIGTNTTDEVPTLSSDCIGAGLNNGTLPNTQSAHFRRLWGYESVS 133 ++ G ++ I N D ++ G L G NT ++ L G + Sbjct: 68 TSYTGLNSNILLNTSAIPDNYKDTKNNKITNPFGGELEVGPAANTSFGYYLTLTGLDKA- 126 Query: 134 SESLSCISSSNVYAGIDKKGTDV 156 +C+S + + G KG V Sbjct: 127 ----ACVSLATLNLGTSAKGYGV 145
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.2 bits (73), Expect = 5e-04 Identities = 10/24 (41%), Positives = 18/24 (75%), Gaps = 2/24 (8%) Query: 13 QRGFSLIEVLVALVIL--VIGLIG 34 QRGF+L+E++V +VI+ + L+ Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVV 30
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 59.8 bits (145), Expect = 6e-12 Identities = 51/320 (15%), Positives = 95/320 (29%), Gaps = 80/320 (25%) Query: 66 ITPAVKGLVISVDVKPNTPIKQGDVLFRIDPTPFEAVVKRKRAALLAA------------ 113 I P +V + VK +++GDVL ++ EA + +++LL A Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 114 ----------------------EQEVPQLEAAWESAKANVARVAADRERNKSAYDRYEQG 151 E+EV +L + + + +E N Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 152 H----RKGGANSPFTELELDNRRQLF----------LASEAQLTAAQAE----------- 186 + S + LD+ L L E + A E Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 187 -----ELRARLA-----YESNVDG----VNSKVAGLQGDLESALYNLEQTVVRAPADGIV 232 + +++ + + L +L + +V+RAP V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 233 TQMALR-PGAMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLL-RLQEGDEAEVVLDAAPGQ 290 Q+ + G V +M +P++ A QN + + G A + ++A P Sbjct: 339 QQLKVHTEG--GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYT 396 Query: 291 ---VFKGKVAKVLPAMAEGE 307 GKV + E + Sbjct: 397 RYGYLVGKVKNINLDAIEDQ 416
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 77.0 bits (189), Expect = 1e-17 Identities = 42/192 (21%), Positives = 70/192 (36%), Gaps = 34/192 (17%) Query: 89 RGLGSGVIIDADKGYIVTNNHVIDGADDIQVGLH------------DGREVKAKLIGTDS 136 + SGV++ K ++TN HV+D L +G ++ Sbjct: 101 TFIASGVVVG--KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSG 158 Query: 137 ESDIALLQIEA--------KNLVAIKTSDSDELRVGDFAVAIGNPFGLGQTVTSGIVSAL 188 E D+A+++ + + S++ E +V G P V+ + Sbjct: 159 EGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP-------VATM 211 Query: 189 GRSGLGIEMLEN-FIQTDAAINSGNSGGALVNLKGELIGINTAIVAPGGGNVGIGFAIPA 247 S I L+ +Q D + GNSG + N K E+IGI+ G N G Sbjct: 212 WESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG----GVPNEFNGAVFIN 267 Query: 248 NMVKNLVAQIAE 259 V+N + Q E Sbjct: 268 ENVRNFLKQNIE 279
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 74.3 bits (182), Expect = 6e-17 Identities = 35/177 (19%), Positives = 66/177 (37%), Gaps = 33/177 (18%) Query: 81 GSLQGLGSGVIMSKEGYILTNYHVIKKADEIVVALQ------------DGRKFTSEVVGF 128 + + SGV++ K +LTN HV+ AL+ +G ++ + Sbjct: 98 PTGTFIASGVVVGK-DTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKY 156 Query: 129 DPETDLSVLKIE--------GDNLPTVPVNLDSPPQVGDVVLAIGNPYNLGQTITQGIIS 180 E DL+++K G+ + ++ ++ QV + G P + T Sbjct: 157 SGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMW--E 213 Query: 181 ATGRNGLSSGYLDFLQTDAAINAGNSGGALIDTNGSLIGINTAAFQVGGEGGGHGIN 237 + G+ G +Q D + GNSG + + +IGI+ G + N Sbjct: 214 SKGKITYLKGE--AMQYDLSTTGGNSGSPVFNEKNEVIGIHWG-------GVPNEFN 261
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 28.1 bits (62), Expect = 0.021 Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 9/73 (12%) Query: 73 FQDSVARLSDFDFGFMPLLPEEEEPLSQRVEALSLWTQSFLTGIAIIQPKLNKASAEVRE 132 +A SD + P++ E +PL +SLW Q + I ++ P L A + Sbjct: 66 LSSLLAVYSDHIYRNQPMMIRENKPL------ISLWAQWY---IGLMVPPLMLALLTQEK 116 Query: 133 VIKDLAEIAQVEF 145 + E EF Sbjct: 117 ALDVSPEHFHAEF 129
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 46.2 bits (109), Expect = 3e-08 Identities = 52/257 (20%), Positives = 97/257 (37%), Gaps = 31/257 (12%) Query: 5 IIITGVGKRIGYALAKHLLAQGHKVIG-----TYRSHYPSIDELQSLGATLIQCDFYDNT 59 ITG + IG A+A+ L +QG + S + ++ A D D+ Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 60 QLQTLIEQL-SQYPKIRAIIHNASDWLPDNSPSLAAHEVMQRMMQVHVSVPYQMNLALAS 118 + + ++ + I +++ A P SL+ E + V+ + + + +++ Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEW-EATFSVNSTGVFNASRSVSK 129 Query: 119 QLRAGAEGEIG--ASDIIHFTDYVAEKGSAKHMAYAASKAALDNLTLSFAAKLAPE-VKV 175 + G I S+ V A AYA+SKAA T +LA ++ Sbjct: 130 YMMDRRSGSIVTVGSNPAG----VPRTSMA---AYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 176 NAIAPAMI-------LFNPSDDEAYRQKTLAKAI-----LPKEAGNQEIIALVDYLLASR 223 N ++P L+ + K + L K A +I V +L++ + Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 224 --YVTGRSHNVDGGRHL 238 ++T + VDGG L Sbjct: 243 AGHITMHNLCVDGGATL 259
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 147 bits (372), Expect = 2e-48 Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 5/150 (3%) Query: 6 NQDDLVRIFKAILKEERFGSQSEIVAALQAEGFSNINQSKVSRMLSKFGAVRTRNAKQEM 65 N+ + I+ +Q E+V L+ +G+ N+ Q+ VSR + + V+ Sbjct: 2 NKGQRHIKIREIITANEIETQDELVDILKKDGY-NVTQATVSRDIKELHLVKVPTNNGSY 60 Query: 66 VYCLPAELGVPTAGSPLKNLV---LDVDHNQAMIVVRTSPGAAQLIARLLDSIGKPEGIL 122 Y LPA+ ++L+ + +D +IV++T PG AQ I L+D++ E I+ Sbjct: 61 KYSLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE-IM 119 Query: 123 GTIAGDDTIFICPSSIQDIADTLETIKSLF 152 GTI GDDTI I + D + I L Sbjct: 120 GTICGDDTILIICRTHDDTKVVQKKILELL 149
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 35.9 bits (83), Expect = 6e-05 Identities = 28/123 (22%), Positives = 43/123 (34%), Gaps = 23/123 (18%) Query: 1 MKIAVLGASGWIGGTIFNEARSRGHEVVAL-----VRDPS-------KLGETEAEVRSVD 48 MK V GA+G+IG + GH+VV + D S L + + +D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 49 LT-QPLEADTFA--GVDVVI---AAVGARAEQNHGIVAKTVN-----NLLAVLPQAKVPR 97 L + D FA + V + R + N N+L K+ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 98 LLW 100 LL+ Sbjct: 121 LLY 123
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 3e-06 Identities = 44/269 (16%), Positives = 91/269 (33%), Gaps = 49/269 (18%) Query: 25 SSVQATAIRPVKLFEVVQLEGGDFRTFPAR--VSANSRAELSFRISGELTDLALVEGQ-- 80 +V A R L V + DF + + ++ ++ E + + +L + + Q Sbjct: 217 LTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLE 276 Query: 81 QIRQGSLLAKLDDRDAHNNLMTREAEHELLAADFQRKTELLKRKLISQAEFDSTQAQLKS 140 QI L AK E++L+ F+ + + Q + Sbjct: 277 QIESEILSAKE--------------EYQLVTQLFKNEI----LDKLRQT-----TDNIGL 313 Query: 141 AKAALAAARDQLSYTKLIAPFSGTVAKRLVDNH-QIVQANQGILTL-QNNNLLDVSIQVP 198 LA ++ + + AP S V + V +V + ++ + ++ L+V+ V Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQ 373 Query: 199 EAMAASLNTYVQQQNFTAKVRFSALAGMEF---DAKFKEYSTQVTPGTQ---AYEVVFSL 252 + A ++ A + K K + + + V+ S+ Sbjct: 374 NKDIGFI-----NVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISI 428 Query: 253 PQP------KDIQLLPGMSAELTLALVKT 275 + K+I L GM+ A +KT Sbjct: 429 EENCLSTGNKNIPLSSGMAVT---AEIKT 454 Score = 28.6 bits (64), Expect = 0.037 Identities = 11/84 (13%), Positives = 30/84 (35%), Gaps = 5/84 (5%) Query: 68 SGELTDLALVEGQQIRQGSLLAKLDDRDAHNNLMTREAEHELLAADFQRKTELLKRKLIS 127 + + ++ + EG+ +R+G +L KL A + + ++ + R + L Sbjct: 104 NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTR-----YQILSR 158 Query: 128 QAEFDSTQAQLKSAKAALAAARDQ 151 E + + ++ Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEE 182
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 502 bits (1294), Expect = e-163 Identities = 207/1046 (19%), Positives = 443/1046 (42%), Gaps = 53/1046 (5%) Query: 3 IAEYSIRHKVISWMFVLLLLVGGGVSFTGLGQLEFPEFTIKEALVITAYPGASPEQVEEE 62 +A + IR + +W+ ++L++ G ++ L ++P V YPGA + V++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VTLPLEDALQQLDAVKHVTSI-NSAGLSQIQIEIKENYDKTSLPQVWDEVRRKVNDTAGQ 121 VT +E + +D + +++S +SAG I + + T +V+ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQ---SGTDPDIAQVQVQNKLQLATPL 117 Query: 122 LPPGTSTPKVFDDFGD---VYGILFNLSGPDYSNRELSNYAD-YLRREIVLVPGVKKVSV 177 LP + + + F P + ++S+Y ++ + + GV V + Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 178 AGSVTEQVVIEISQQRLSALGLDQSYIYGLINNQNVVSNAGSLVVGDN------RIRIHP 231 G+ + I + L+ L + + QN AG L I Sbjct: 178 FGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIA 236 Query: 232 TGEFSSVQDLARLIVSPPGSTELIYLGDIANIEKDYDETPDVLYHNRGETALSLGISFSS 291 F + ++ ++ + ++ L D+A +E + + N G+ A LGI ++ Sbjct: 237 QTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARIN-GKPAAGLGIKLAT 295 Query: 292 GVNVVEVGKSVSQRLAELESQRPIGMNLDTVYNQSLAVDDTVNGFLINLLESIAIVIAVL 351 G N ++ K++ +LAEL+ P GM + Y+ + V +++ + L E+I +V V+ Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 352 LLFMG-LRSGLLMGLILLLTILGTFIVMKVLGIELQLISLGALIIALGMLVDNAIVVTEG 410 LF+ +R+ L+ + + + +LGTF ++ G + +++ +++A+G+LVD+AIVV E Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 411 ILIGLRRGKTR-LEAAKQIVSQTQWPLLGATVIAIIAFAPIGLSQNAAGEFCRSLFQVLM 469 + + K EA ++ +SQ Q L+G ++ F P+ + G R ++ Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 470 ISLFISWITAITLTPFFCHLLFKDAPADDEEEQDPYKGWF-------FSLYRVSLTFALR 522 ++ +S + A+ LTP C L K A+ E + + GWF + Y S+ L Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILG 535 Query: 523 FRLASIVLVGVMLVSAVIGFGHIKNVFFPASNTPIFFVDIWMPEGTDIKGTERFTADIEK 582 +++ +++ V+ F + + F P + +F I +P G + T++ + Sbjct: 536 STGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTD 595 Query: 583 LLLKQAEEQHSGLKHLTSVIG-------QGAQRFILPYQPEKGYPAYAQLIIEMEDLASL 635 LK + ++ + +V G Q A + +P + + Sbjct: 596 YYLKNEKA---NVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSA--EAVIHRA 650 Query: 636 KVYMPELETLLNQRFPQAQYRFKNMENGPSPAAKIEARFYGDDPEVLRALGAQAEAIFNA 695 K+ + ++ F + ++ + + +A Sbjct: 651 KMELGKIRDGFVIPFNMP--AIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQH 708 Query: 696 EPSMDGIRHDWRNQVPLIRPQLENAQARETGISKQDLDNALLINFSGKQIGLYRETSHLL 755 S+ +R + + +++ +A+ G+S D++ + G + + + + Sbjct: 709 PASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVK 768 Query: 756 PIVARAPAEERLQADSLWKLQIWSTEHNTFVPATQVVSQFETQWENPLVKRRDRMRMLAV 815 + +A A+ R+ + + KL + + + VP + + + +P ++R + + + + Sbjct: 769 KLYVQADAKFRMLPEDVDKLYV-RSANGEMVPFSAFTT-SHWVYGSPRLERYNGLPSMEI 826 Query: 816 LADPKLGSD-ETADSVLHKVKDKVEAISLPTGYHLEWGGEYETAGEAQTAVFSSIPMGYL 874 + G+ A +++ + K LP G +W G + + + + ++ Sbjct: 827 QGEAAPGTSSGDAMALMENLASK-----LPAGIGYDWTGMSYQERLSGNQAPALVAISFV 881 Query: 875 VMFLITVFLFNSVRQPLVIWFTVPLALIGVSAGLLLFDAPFSFMALLGLLSLSGMVIKNG 934 V+FL L+ S P+ + VPL ++GV LF+ ++GLL+ G+ KN Sbjct: 882 VVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNA 941 Query: 935 IVLVDQIN-LELGEGKPAYAALVDSSVSRVRPVLMAAITTMLGMIPLIPDAFFGS----- 988 I++V+ L EGK A + + R+RP+LM ++ +LG++PL GS Sbjct: 942 ILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNA 1001 Query: 989 MAITIIFGLGFASLLTLIVLPVMYSL 1014 + I ++ G+ A+LL + +PV + + Sbjct: 1002 VGIGVMGGMVSATLLAIFFVPVFFVV 1027 Score = 73.3 bits (180), Expect = 3e-15 Identities = 43/219 (19%), Positives = 93/219 (42%), Gaps = 13/219 (5%) Query: 814 AVLADPKLGSDETADSVLHKVKDKVEAI--SLPTGYHLEWGGEYETAGEAQTA---VFSS 868 A KL + A +K K+ + P G ++ Y+T Q + V + Sbjct: 286 AAGLGIKLATGANALDTAKAIKAKLAELQPFFPQG--MKVLYPYDTTPFVQLSIHEVVKT 343 Query: 869 IPMGYLVMFLITVFLFNSVRQPLVIWFTVPLALIGVSAGLLLFDAPFSFMALLGLLSLSG 928 + +++FL+ ++R L+ VP+ L+G A L F + + + G++ G Sbjct: 344 LFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIG 403 Query: 929 MVIKNGIVLVDQINLELGEGKPAYAALVDSSVSRVR-PVLMAAITTMLGMIPL-----IP 982 +++ + IV+V+ + + E K + S+S+++ ++ A+ IP+ Sbjct: 404 LLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGST 463 Query: 983 DAFFGSMAITIIFGLGFASLLTLIVLPVMYSLAFNIKPN 1021 A + +ITI+ + + L+ LI+ P + + Sbjct: 464 GAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSA 502
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 35.3 bits (81), Expect = 5e-04 Identities = 21/110 (19%), Positives = 40/110 (36%), Gaps = 15/110 (13%) Query: 412 GEILGIE---HKQELVDLHRANGRNVVQGDAADTDFWEKLDKAPNLELVLLAMPHHTGNL 468 +I+G+E ++ ANG ++VQG A + + + +A T Sbjct: 209 NQIVGVEVSVQDGGTYNITMANGYSLVQGSTARQ--LAAVPSSADPSRTTVAYVDGTAG- 265 Query: 469 FAVEQLKKLNYQGKLSAIV--------QYGDDAASLRTSGVHSVYNLYEA 510 +E +KL G L I+ Q + L + + ++A Sbjct: 266 -NIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNTQHKA 314
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.031 Identities = 11/41 (26%), Positives = 21/41 (51%), Gaps = 4/41 (9%) Query: 124 LAAGLSSSGALVVAFGTAISDSSQLHLSPMAVAQLAQRGEY 164 A GLS+S A +A++ L +SP++ +A + + Sbjct: 296 AAQGLSTSAAAAGLIASAVT----LAISPLSFLSIADKFKR 332
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 31.6 bits (71), Expect = 0.005 Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 10/79 (12%) Query: 268 PSPD---SGVTLPNQLPVP---AADHPAEEAKPDAGTGST-NPQGAAANASAPSNAAPNT 320 P PD PN P+P A++PA P+ G+ NP+ + +A P+T Sbjct: 311 PRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPE---PDPDLNPDANPDT 367 Query: 321 TAPNTTVPNTGATPSNANG 339 T P++ A P NG Sbjct: 368 DGQPGTRPDSPAVPDRPNG 386
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 557 bits (1437), Expect = 0.0 Identities = 315/348 (90%), Positives = 333/348 (95%), Gaps = 1/348 (0%) Query: 1 MFKKLRGIFSNDLSIDLGTANTLIYVRDEGIVLNEPSVVAIRGERSSSGQKSVAAVGTEA 60 M KK RG+FSNDLSIDLGTANTLIYV+ +GIVLNEPSVVAIR +R+ S KSVAAVG +A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGS-PKSVAAVGHDA 59 Query: 61 KQMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGAT 120 KQMLGRTPGNI AIRPMKDGVIADF+VTEKMLQHFIKQVH+NSF RPSPRVLVCVPVGAT Sbjct: 60 KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGAT 119 Query: 121 QVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLN 180 QVERRAIRESA GAGAREV+LIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVA+ISLN Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN 179 Query: 181 GVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR 240 GVVYSSSVRIGGD+FD+AIINYVRRNYGSLIGEATAERIKH IG+AYPGDEV EIEVRGR Sbjct: 180 GVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGR 239 Query: 241 NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGAL 300 NLAEGVPR FTLNSNEILEALQEPL+GIVSAVMVALEQ PPELASDISERGMVLTGGGAL Sbjct: 240 NLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL 299 Query: 301 LRDLDRLLMQETGIPVMVADDPLTCVARGGGKALEMIDMHGGDLFSEE 348 LR+LDRLLM+ETGIPV+VA+DPLTCVARGGGKALEMIDMHGGDLFSEE Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.9 bits (80), Expect = 1e-04 Identities = 12/24 (50%), Positives = 19/24 (79%) Query: 8 RMARSKRGFTLVEMVTVILILGIL 31 R +RGFTL+E++ VI+I+G+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVL 25
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 37.6 bits (87), Expect = 8e-06 Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 4/58 (6%) Query: 21 KQQGFTLIELVVGMLVIAIAIVM-LSSMLFPQADRAAKTLHRVKSA-ELA--HSVMNE 74 +Q+GFTL+E+++ +L++ ++ M L + + D AA+TL R ++ + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTG 59
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 41.9 bits (98), Expect = 2e-07 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 1/80 (1%) Query: 8 RQFGFTLVELVTTIILIGILSVAVLPRLFSQSSYSAFSLRNEFMAELRQVQQKALNNTDR 67 RQ GFTL+E++ ++L+G+ + VL + SA F A+LR VQQ+ L + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQT-GQ 60 Query: 68 CYRVVVSAMGYQVSQFASRD 87 + V V +Q +RD Sbjct: 61 FFGVSVHPDRWQFLVLEARD 80
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 49.9 bits (119), Expect = 2e-10 Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 4/53 (7%) Query: 1 MKKQSGFTLIELVVVIIILGILAVTAAPKFINLQSDARA----STVKGLESAI 49 KQ GFTL+E++VVI+I+G+LA P + + A S + LE+A+ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENAL 56
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 44.9 bits (106), Expect = 1e-08 Identities = 14/31 (45%), Positives = 23/31 (74%) Query: 2 MKRQQGFTLIELVVVIIILGILAVTAAPKFI 32 +Q+GFTL+E++VVI+I+G+LA P + Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLM 34
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 42.6 bits (100), Expect = 1e-07 Identities = 15/36 (41%), Positives = 27/36 (75%) Query: 4 KQDGFSLIELVIVIVILGLLAATAIPRFLNVTDDAE 39 KQ GF+L+E+++VIVI+G+LA+ +P + + A+ Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKAD 41
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 303 bits (777), Expect = e-102 Identities = 118/407 (28%), Positives = 208/407 (51%), Gaps = 6/407 (1%) Query: 1 MPVYQYRGRSGQGQAVTGQLDAASEGAAADMLLARGIIPLEVKV----AKETKSFTLAQL 56 M Y Y+ QG+ G +A S A +L RG++PL V +++ S L+ Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 57 FKRKVGLDELQIFTRQMYSLTRSGIPILRAIAGLSETAHSQRMKDALNDISEQLTAGRPL 116 K ++ +L + TRQ+ +L + +P+ A+ +++ + + + + ++ G L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 117 SSAMNQHPDVFDSLFVSMVHVGENTGKLEDAFIQLSGYIEREQETRRRIKAAMRYPIFVL 176 + AM P F+ L+ +MV GE +G L+ +L+ Y E+ Q+ R RI+ AM YP VL Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPC-VL 179 Query: 177 IAIALAMV-ILNIMVIPKFAEMFARFGADLPWATKVLIGTSNLFVNYWPLMLIILLGTVI 235 +A+A+V IL +V+PK E F LP +T+VL+G S+ + P ML+ LL + Sbjct: 180 TVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFM 239 Query: 236 GIRYWHHTEKGEKQWDQWKLHIPAVGSIIERSTLSRYCRSFSMMLSAGVPMTQALSLVAD 295 R EK + + LH+P +G I +RY R+ S++ ++ VP+ QA+ + D Sbjct: 240 AFRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGD 299 Query: 296 AVDNAYMHDKIVGMRRGIESGESMLRVSNQSKLFTPLVLQMVAVGEETGQIDQLLNDAAD 355 + N Y ++ + G S+ + Q+ LF P++ M+A GE +G++D +L AAD Sbjct: 300 VMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAAD 359 Query: 356 FYEGEVDYDLKNLTAKLEPILIGIVAVIVLVLALGIYLPMWDMLNVV 402 + E + EP+L+ +A +VL + L I P+ + ++ Sbjct: 360 NQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.4 bits (86), Expect = 1e-04 Identities = 28/168 (16%), Positives = 57/168 (33%), Gaps = 13/168 (7%) Query: 89 IDTSPLETETTTSTEPTAEM-----------AQVSPSSTDAPAKDMSTSAESAPRVAQSP 137 +DT+ + T + + A V P + P++ T AE++ + +++ Sbjct: 992 VDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTV 1051 Query: 138 RVNAAQVEPTSEPTTESVAAHTSSDTPNKAALTQESVQTQAESQQVAVKANQADVNASQS 197 N T+ E S+ N ++ + Q A V + Sbjct: 1052 EKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEK-EE 1110 Query: 198 EVKITQTEAKASEPVVPAGAQVSSQASTQASSQASAQAQSTGKMAIRE 245 + K+ +TE P V + + S QA ++ + I+E Sbjct: 1111 KAKV-ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Score = 35.4 bits (81), Expect = 5e-04 Identities = 22/138 (15%), Positives = 45/138 (32%), Gaps = 5/138 (3%) Query: 103 EPTAEMAQVSPSSTDAP---AKDMSTSAESAPRVAQSPRVNAAQVEPTSEPTTESVAAHT 159 + Q P+ + P K+ + + Q + ++ VE +T ++ Sbjct: 1135 QSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194 Query: 160 SSDTPNKAALTQESVQTQAESQQVAVKANQADVNASQSEVKITQTEAKASEPVVPAGAQV 219 + P +ES ++ V + V+ T + V A + Sbjct: 1195 VVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTV--ALCDL 1252 Query: 220 SSQASTQASSQASAQAQS 237 +S + S A A+AQ Sbjct: 1253 TSTNTNAVLSDARAKAQF 1270
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 187 bits (476), Expect = 7e-54 Identities = 78/317 (24%), Positives = 144/317 (45%), Gaps = 28/317 (8%) Query: 237 ELKETLSAIIGDTGGGRQVVVT--PQAGLVTIRAYPNELRQVRAFLNSAESHLQRQVILE 294 ++ A + +++ Q + + A P+ + + + + + QV++E Sbjct: 292 TMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIR-RPQVLVE 350 Query: 295 AKILEVTLSDGYQQGIQWDNVLGHV---GNTNINFGTSAGAGLS----DKITASLGGVTS 347 A I EV +DG GIQW N + N+ + T+ +++SL S Sbjct: 351 AIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALS 410 Query: 348 ------LSIKGSDFNTMISLLDTQGDVDVLSSPRVTASNNQKAVIKVGTDEYFVTDVSST 401 ++ +++ L + D+L++P + +N +A VG + +T S Sbjct: 411 SFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLT--GSQ 468 Query: 402 TVAGTTPVTTPQVELTPFFSGIALDVTPQIDKDGNVLLHVHPSVIDVKEQTKDIKVSSES 461 T +G T + + GI L V PQI++ +VLL + V V + SS S Sbjct: 469 TTSGDNIFNTVERKTV----GIKLKVKPQINEGDSVLLEIEQEVSSVADAA-----SSTS 519 Query: 462 LELPLAQSEIRESDTVIRAASGDVVVIGGLMKSENTEVVSQVPLLGDIPLVGELFKNRSK 521 +L + R + + SG+ VV+GGL+ ++ +VPLLGDIP++G LF++ SK Sbjct: 520 SDLGATFN-TRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSK 578 Query: 522 QKKKTELIIMLKPTVVG 538 + K L++ ++PTV+ Sbjct: 579 KVSKRNLMLFIRPTVIR 595
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 60.4 bits (146), Expect = 6e-14 Identities = 16/79 (20%), Positives = 33/79 (41%), Gaps = 1/79 (1%) Query: 54 RVHPEYPIEAAKNGISGCVALVVGINSSGKPSGYKVKKSYPEGVFDNYATAALANWRWKA 113 R P+YP A I G V + + G+ ++ + P +F+ A+ WR++ Sbjct: 162 RNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEP 221 Query: 114 TDKNSDKKPVLTIIQMDFS 132 K V + +++ + Sbjct: 222 G-KPGSGIVVNILFKINGT 239
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.7 bits (212), Expect = 7e-22 Identities = 37/170 (21%), Positives = 61/170 (35%), Gaps = 16/170 (9%) Query: 3 TKLQLYLVDDDEAILDSLGFMLGQFGYQVQTFSSGRDFLAQCPLTQAGCVILDSRMPEIT 62 T + + DDD AI L L + GY V+ S+ V+ D MP+ Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GQEVQQKLLETQSPLGVIFLTGHGDLPMALSAFRKGACDFFQKPVSGKALVQAIEKAHKE 122 ++ ++ + + L V+ ++ A+ A KGA D+ KP L+ I +A E Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 123 SQASFEQLYLQQKFAQLTEREQQVLAHVVQGMTNKQISEAMYLSLRTIEV 172 + R ++ GM S AM R + Sbjct: 122 PKR----------------RPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 70.6 bits (173), Expect = 5e-16 Identities = 37/158 (23%), Positives = 62/158 (39%), Gaps = 20/158 (12%) Query: 3 NIMVTGATGLLGRAVVKQLTAAGHRVIA---------TGFSRAEAGI--------HRLDL 45 +VTGA G +G V K+L AGH+V+ +A + H++DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 46 TQAAEVEAFIAREQPEVIVHCAAERRPDVSERSPEHALALNLSASQTLAEAAKNHQ-AWL 104 + A E + S +P NL+ + E ++++ L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 105 LYISTDYVF-DGTTPPYAEDAEPN-PVNFYGASKLQGE 140 LY S+ V+ P++ D + PV+ Y A+K E Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE 159
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.4 bits (92), Expect = 1e-05 Identities = 45/221 (20%), Positives = 81/221 (36%), Gaps = 36/221 (16%) Query: 109 AQIHELEKQLSQLELNNLSLNAEILTQLQQRIDVAAEGVTRQNGLLDSFERYQRKGVVPT 168 Q + Q Q ELN AE LT L + ++ LD F K + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSR-LDDFSSLLHKQAIAK 251 Query: 169 ----------ADMAAVLQAHTASKMALE----QAKVDLMQARQAQKTELLAGPIAQSKYN 214 + L+ + + +E AK + Q K E+L + Q+ N Sbjct: 252 HAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL-DKLRQTTDN 310 Query: 215 ---VELQLARLKAQESQLDIKALTPTRVVDV-------LVQAGEHIVEDRPLVLLSGREA 264 + L+LA+ + ++ I+A +V + +V E ++ P + Sbjct: 311 IGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPE-----DDT 365 Query: 265 AVIFAYLEPKYLEYTAIGQEATIKLP--NGTR---LRGEIS 300 + A ++ K + + +GQ A IK+ TR L G++ Sbjct: 366 LEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVK 406
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 33.6 bits (77), Expect = 6e-04 Identities = 20/90 (22%), Positives = 31/90 (34%), Gaps = 17/90 (18%) Query: 164 IGYEKAFEQIRTGDVIYCDPP-------YAPLSTTASFTTYVGAGFSLDDQALLARYSRH 216 I E ++ V+ +P Y T T+ D Q R Sbjct: 245 IQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYT----DAQVQ---TVRK 297 Query: 217 MALEQRIPVVISNHDIPLTRELYRGAHLAK 246 +A E+ +P++ IPL R LY A + Sbjct: 298 IAEEEGVPIL---QRIPLARALYWDALVDH 324
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.024 Identities = 16/65 (24%), Positives = 24/65 (36%) Query: 14 ALVERLHHVASYSDQLLVLVGAHGSGKTTLLTALATDFDESNAALVICPMHADNAEIRRK 73 V R+ D +VL G G GK+TL+ L S+ I +I Sbjct: 583 GHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGI 642 Query: 74 ILVQL 78 + +L Sbjct: 643 VAYEL 647
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.002 Identities = 16/64 (25%), Positives = 25/64 (39%), Gaps = 8/64 (12%) Query: 9 LVGPMGAGKSTIGRHLAQML-----HLEFHDSDQEIEQRTGADIAWVFDVEGEEGFRRRE 63 L G G GKST+ L + H + EQ G +++ FRR + Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAG---IVAYELSEMTAFRRAD 657 Query: 64 AQVI 67 A+ + Sbjct: 658 AEAV 661
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 248 bits (635), Expect = 3e-75 Identities = 99/411 (24%), Positives = 188/411 (45%), Gaps = 38/411 (9%) Query: 306 GDITLRLDDVPWDQALDLILQTKGLDKRIEGNILMVAPSEELAIRESQNLKNKQEVKELA 365 GD ++ + W A D++ L+K + L + + E N Sbjct: 190 GDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSR 249 Query: 366 PLYSEYLQ----------------INYAKATDIAELLKGADSSLLSPRG----------- 398 ++ + YAKA+D+ E+L G S++ S + Sbjct: 250 QRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKN 309 Query: 399 -SVAVDERTNTVLVKDTAEIIENIHRLVEVLDIPIRQVLIESRMVTVKDDVSEDLGIRWG 457 + +TN ++V +++ ++ R++ LDI QVL+E+ + V+D +LGI+W Sbjct: 310 IIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWA 369 Query: 458 VTDQQGSKGTSGTLEGAGSIANGTVPTLDNRLNVNLPAAVTNPTSIAFHVAKLADGTILD 517 + ++ T+ L + +IA D ++ +L +A+++ IA + Sbjct: 370 NKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGN----WA 425 Query: 518 LELSALEQENKGEIIASPRITTSNQKAAYIEQGVEIPYV-----QSTSSGATSVTFKKAV 572 + L+AL K +I+A+P I T + A G E+P + S + +V K Sbjct: 426 MLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVG 485 Query: 573 LSLRVTPQITPDNRVILDLEITQDSQGKT-VDTPTGPAVAIDTQRIGTQVLVDNGETIVL 631 + L+V PQI + V+L++E S T + +T+ + VLV +GET+V+ Sbjct: 486 IKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVV 545 Query: 632 GGIYQQNLISRVSKVPILGDIPLVGFLFRNTTDKNERQELLIFVTPKIVNE 682 GG+ +++ KVP+LGDIP++G LFR+T+ K ++ L++F+ P ++ + Sbjct: 546 GGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRD 596 Score = 46.8 bits (111), Expect = 2e-07 Identities = 33/175 (18%), Positives = 75/175 (42%), Gaps = 14/175 (8%) Query: 275 SLNFQNISVRTVLQIIADYNNFNLVTSDTVEGDITLR-LDDVPWDQALDLILQTKGLDKR 333 S +F+ ++ + ++ N ++ +V G IT+R D + +Q L Sbjct: 31 SASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVL----D 86 Query: 334 IEGNILMVAPSEELAIRESQNLKNKQEVK--ELAP-----LYSEYLQINYAKATDIAELL 386 + G ++ + L + S++ K + AP + + + + A D+A LL Sbjct: 87 VYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLL 146 Query: 387 KGADSSLLSPRGSVAVDERTNTVLVKDTAEIIENIHRLVEVLDIPIRQVLIESRM 441 + + + + GSV E +N +L+ A +I+ + +VE +D + ++ + Sbjct: 147 RQLNDN--AGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPL 199
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 44.0 bits (104), Expect = 5e-07 Identities = 32/156 (20%), Positives = 58/156 (37%), Gaps = 34/156 (21%) Query: 199 VDIGANMTTFSVVESGETTFIREQAFGGELFTQSILSFYGMSY------EQAEKAKIE-- 250 VDIG T +V+ + GG+ F ++I+++ +Y AE+ K E Sbjct: 164 VDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIG 223 Query: 251 -------------------GDLPRNY------MFEVLSPFQTQLLQQIKRTLQIYCTSSG 285 +PR + + E L T ++ + L+ Sbjct: 224 SAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELA 283 Query: 286 KDKVDY-LVLCGGTSKLEGMANLLTNELGVHTIIAD 320 D + +VL GG + L + LL E G+ ++A+ Sbjct: 284 SDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAE 319