>PF08280#M protein trans-acting positive regulator Length = 530 Score = 284 bits (729), Expect = 2e-96 Identities = 122/213 (57%), Positives = 163/213 (76%) Query: 5 KKKKDSFLVETYLEQSIRDKSELVLLLFKSPTIIFSHVAKQTGLTAVQLKYYCKELDDFF 64 +K+ L+E YLE SI K +LV+L FK+ ++ + VA++TGLT +QL +YC+EL+ FF Sbjct: 27 RKRGPLSLIEKYLESSIESKCQLVVLFFKTSSLPITEVAEKTGLTFLQLNHYCEELNAFF 86 Query: 65 GNNLDITIKKGKIICCFVKPVKEFYLHQLYDTSTILKLLVFFIKNGTTSQPLIKFSKKYF 124 ++L +TI+K I C F P KE YL+QLY +S +L+LL F IKNG+ S+PL F++ +F Sbjct: 87 PDSLSMTIQKRMISCQFTHPSKETYLYQLYASSNVLQLLAFLIKNGSHSRPLTDFARSHF 146 Query: 125 LSSSSAYRLRESLIKLLREFGLRVSKNTIVGEEYRIRYLIAMLYSKFGIVIYPLDHLDNQ 184 LS+SSAYR+RE+LI LLR F L++SKN IVGEEYRIRYLIA+LYSKFGI +Y L D Sbjct: 147 LSNSSAYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKFGIKVYDLTQQDKN 206 Query: 185 IIYRFLSQSATNLRTSPWLEEPFSFYNMLLALS 217 II+ FLS S+T+L+TSPWL E FSFY++LLALS Sbjct: 207 IIHSFLSHSSTHLKTSPWLSESFSFYDILLALS 239
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 888 bits (2297), Expect = 0.0 Identities = 565/574 (98%), Positives = 570/574 (99%) Query: 1 MKDMSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSEL 60 MKDMSNKK FKKYSRVAGLLTAALI+GNLVTANA+SNKQNTA+TETTTTNEQPKPESSEL Sbjct: 1 MKDMSNKKIFKKYSRVAGLLTAALIVGNLVTANADSNKQNTANTETTTTNEQPKPESSEL 60 Query: 61 TTEKAGQKTDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLN 120 TTEKAGQK DDMLNSNDMIKLAPKEMPLESAEKEEKKSED KKSEEDHTEEINDKIYSLN Sbjct: 61 TTEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDNKKSEEDHTEEINDKIYSLN 120 Query: 121 YNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDRTYPAA 180 YNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDRTYPAA Sbjct: 121 YNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDRTYPAA 180 Query: 181 LQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWH 240 LQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWH Sbjct: 181 LQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWH 240 Query: 241 DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAY 300 DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAY Sbjct: 241 DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAY 300 Query: 301 KQIFYTVSANLPNNPADVFDKSVTFKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSK 360 KQIFYTVSANLPNNPADVFDKSVT KELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSK Sbjct: 301 KQIFYTVSANLPNNPADVFDKSVTLKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSK 360 Query: 361 SNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIK 420 SNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIK Sbjct: 361 SNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIK 420 Query: 421 DNATFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHRGAYVAQY 480 DNATFSRKNPAYPISYTSVFLKNNKIAGVNNR+EYVETTSTEYTSGKINLSH+GAYVAQY Sbjct: 421 DNATFSRKNPAYPISYTSVFLKNNKIAGVNNRSEYVETTSTEYTSGKINLSHQGAYVAQY 480 Query: 481 EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEW 540 EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEW Sbjct: 481 EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEW 540 Query: 541 WRKVIDERDVKLSKEINVNISGSTLSPYGSITYK 574 WRKVIDERDVKLSKEINVNISGSTLSPYGSITYK Sbjct: 541 WRKVIDERDVKLSKEINVNISGSTLSPYGSITYK 574
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.9 bits (223), Expect = 5e-23 Identities = 29/116 (25%), Positives = 62/116 (53%), Gaps = 2/116 (1%) Query: 1 MTK-KILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLILLDLMLPEM 59 MT IL+ +D+ + ++ L GY+V + N + DL++ D+++P+ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 DGFEVTRRLQTE-KTTYIMMMTARDSIMDVVAGLDRGADDYIVKPFAIEELLARIR 114 + F++ R++ +++M+A+++ M + ++GA DY+ KPF + EL+ I Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.007 Identities = 18/110 (16%), Positives = 41/110 (37%), Gaps = 27/110 (24%) Query: 390 LMILIDNAVKYSRKEKKIAINLSVTGKQE---AIVRVQDKGEGISKEDIEHIFERFYRTD 446 + L++N +K+ + + + G ++ + V++ G K E Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE---------- 309 Query: 447 KSRNRTSTQAGLGIGLSILK---QIVDGYHLQMKVESELNEGSVFILHIP 493 G GL ++ Q++ G Q+K+ + + + +L IP Sbjct: 310 ----------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVL-IP 348
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 37.1 bits (86), Expect = 1e-04 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 8/87 (9%) Query: 36 GVTRDRIYATGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEG 95 G+T + +W N + ++IDT G D F+ ++ ++ D + ++S K+G Sbjct: 53 GITIQTGITSFQWENTKVNIIDTPGHMD----FLAEVYR----SLSVLDGAILLISAKDG 104 Query: 96 VTDADEYVSKILYRTNTPVILAVNKVD 122 V + L + P I +NK+D Sbjct: 105 VQAQTRILFHALRKMGIPTIFFINKID 131
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.7 bits (74), Expect = 0.002 Identities = 30/150 (20%), Positives = 51/150 (34%), Gaps = 21/150 (14%) Query: 122 KAAVQRAVEQVTVNYDIYEALGSKRNELYAEIEKSLSERLAKESIELVSVTLTDQDAGDE 181 A V A A S+ E AE K S+ + K + T +++ E Sbjct: 1017 IARVDEAPVP-----PPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKE 1071 Query: 182 -----------IEKAIKDESVKQKQVDSAKQ-----DKEKAKIEAETKQIQAQAEADAQV 225 E A K+ Q K+ +EKAK+E E Q + + Sbjct: 1072 AKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSP 1131 Query: 226 IKAKGEAESNNTKAASITDNLIKMKEAEAR 255 + + E + A D + +KE +++ Sbjct: 1132 KQEQSETVQPQAEPARENDPTVNIKEPQSQ 1161
>PF06872#EspG protein Length = 398 Score = 31.2 bits (70), Expect = 0.002 Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 3/35 (8%) Query: 59 RGVGDVKMETEAIDIPFD---VLKKILGYKDGSSS 90 RG+G+ K+ +DIP D +L+ LG KD +SS Sbjct: 208 RGLGNSKLSLNGVDIPADAQKLLRNTLGLKDTNSS 242
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 560 bits (1444), Expect = 0.0 Identities = 254/334 (76%), Positives = 285/334 (85%), Gaps = 2/334 (0%) Query: 1 MTETIPLRVQFKRMTAEEWARSTVILLEGEIGLETDTGYAKFGDGKNRFSKLKYLNKPDL 60 MTETIPLRVQFKRMTAEEW RS VILLE EIG ETDTGYAKFGDGKN+FSKLKYLNKPDL Sbjct: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL 60 Query: 61 DAFAQKKETDNKIAKLESIKADKDTVYLKAESKKELDKKMNLTGGTMTGQLQFKPN-SHI 119 AFAQK+ET++KI KLES KADK+ VYLKAESK ELDKK+NL GG MTGQLQFKPN S I Sbjct: 61 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI 120 Query: 120 KHSSSTGGAINIDMSKSAGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGKTNA 179 K SSS GGAINIDMSKS GA +V+Y+N DT+DGPLM LR+ K+TF+QSA FVDYSGKTNA Sbjct: 121 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA 180 Query: 180 VNIVMRQPSTPNFSSALNITSANEGGSAMQIRGIERALGTLKITHENPNVDAKYDENAAA 239 VNI MRQP+TPNFSSALNITS NE GSAMQIRG+E+ALGTLKITHENPNV+A YDENAAA Sbjct: 181 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA 240 Query: 240 LSIDIVGKRGASGNGTAAQGIFINSSAGTTGKMLRIRNKNKDKFYVNPDGGFHSYADSIV 299 LSIDIV K+ G GTAAQGI+INS++GTTGK+LRIRN DKFYV DGGF++ S + Sbjct: 241 LSIDIV-KKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQI 299 Query: 300 DGNLTVKDPTSGKHAATKDYVDKKFDELKKLIQK 333 DGNL +K+PT+ HAATK YVD + +LK L+ Sbjct: 300 DGNLKLKNPTADDHAATKAYVDSEVKKLKALLMD 333
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 30.0 bits (67), Expect = 0.012 Identities = 26/127 (20%), Positives = 40/127 (31%), Gaps = 28/127 (22%) Query: 91 NTLNPVSTFPEIGAP----TTMDA-EGRIITLEFEDFF-----------VTQVY----TP 130 L P + +P D IT+ + F QVY T Sbjct: 432 QILAPNNYYPSKNLAPIALNAQDDFSSTPITMNYNQFLELEKTKQLRLDTDQVYGNIATY 491 Query: 131 NAGDGLRRLDDRQIWDHKYADYLTELDAQKP--VLAAGDYNVAHKEIDLANPSS--NRRS 186 N +G R+D W ++ L ++ + D N+ + I NPS Sbjct: 492 NFENGRVRVDTGSNW----SEVLPQIQETTARIIFNGKDLNLVERRIAAVNPSDPLETTK 547 Query: 187 PGFTDEE 193 P T +E Sbjct: 548 PDMTLKE 554
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 92.6 bits (230), Expect = 4e-22 Identities = 42/160 (26%), Positives = 64/160 (40%), Gaps = 24/160 (15%) Query: 264 DIDWTQTDDDTKYESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGS 323 + D D HG HV G +A +G+APEA ++ ++V G Sbjct: 74 EGDPEIFKDY---NGHGTHVAGTIAAT-----ENENGVVGVAPEADLLIIKVLNKQGSGQ 125 Query: 324 AESLFIKAIEDAVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNER 383 + + I+ I A+ D+I++SLG L EA++KA + + V+ AAGNE Sbjct: 126 YDWI-IQGIYYAIEQKVDIISMSLGGP-----EDVPELHEAVKKAVASQILVMCAAGNEG 179 Query: 384 VYGSDHDDPLAINPDYGLVGSPSTGRTPTSVAAINSKWVI 423 D+ +G P SV AIN Sbjct: 180 DGDDRTDE----------LGYPGCYNEVISVGAINFDRHA 209 Score = 79.1 bits (195), Expect = 1e-17 Identities = 36/147 (24%), Positives = 58/147 (39%), Gaps = 18/147 (12%) Query: 561 FDSVVSKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMAS 620 ++ V+S + FSN + D+ APG DI ST Y + +GTSMA+ Sbjct: 194 YNEVISVGAINFDRHASEFSNSNN------EVDLVAPGEDILSTVPGGKYATFSGTSMAT 247 Query: 621 PQIAGASLLVKQ-YLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGL 679 P +AGA L+KQ + +L + L+ SP+ +G GL Sbjct: 248 PHVAGALALIKQLANASFERDL----TEPELYAQLIKRT-------IPLGNSPKMEGNGL 296 Query: 680 LNIDGAVTSGLYVTGKDNYGSISLGNI 706 L + + G +S ++ Sbjct: 297 LYLTAVEELSRIFDTQRVAGILSTASL 323 Score = 40.6 bits (95), Expect = 4e-05 Identities = 11/34 (32%), Positives = 18/34 (52%), Gaps = 1/34 (2%) Query: 127 HDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS 160 + ++ W++ G+G VAV+DTG D H Sbjct: 26 VEMIQAPAVWNQTR-GRGVKVAVLDTGCDADHPD 58
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.5 bits (87), Expect = 4e-05 Identities = 23/137 (16%), Positives = 49/137 (35%), Gaps = 10/137 (7%) Query: 3 IFVLEDDFLHQTRIEKIIYKILTDNKLEVNHLEVYGKPNQLLEDISERGRHQLFFLDIDI 62 I V +DD I ++ + L+ +V + L I+ G L D+ + Sbjct: 6 ILVADDD----AAIRTVLNQALSRAGYDV---RITSNAATLWRWIA-AGDGDLVVTDVVM 57 Query: 63 KGEDKKGMEIAVEIRNRDPHAVIVFVTTHSEFMPVSFQYQVSALDFIDKELPEELFSHRI 122 E+ ++ I+ P ++ ++ + FM + A D++ K I Sbjct: 58 PDEN--AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115 Query: 123 EKAITYVQDNQGKTLAE 139 +A+ + K + Sbjct: 116 GRALAEPKRRPSKLEDD 132
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.1 bits (99), Expect = 5e-07 Identities = 24/103 (23%), Positives = 50/103 (48%), Gaps = 9/103 (8%) Query: 28 VLLVSFLVLF---SLFAKKEITITSQGEMTP---TKVIASVQSTSDHTIVVNNLKNNKFI 81 ++ FLV+ S+ + EI T+ G++T +K I ++++ I+V K + + Sbjct: 62 YFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIV---KEGESV 118 Query: 82 KKGDVIIQYSKTMENSQKKALEKQLATLNKQKNGLQILKTSLE 124 +KGDV+++ + + + L ++ QIL S+E Sbjct: 119 RKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIE 161
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 40.0 bits (93), Expect = 2e-06 Identities = 19/87 (21%), Positives = 32/87 (36%), Gaps = 6/87 (6%) Query: 7 TKKKIAKAFKKQLAVKSFEKISVVDIMDQAQIRRQTFYNHFLDKYELLDWIFETE---LQ 63 T++ I + + + S+ +I A + R Y HF DK +L I+E + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 64 EQVTHNLNYISGS---QLLDELLFYFE 87 E G L + L+ E Sbjct: 72 ELELEYQAKFPGDPLSVLREILIHVLE 98
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.8 bits (228), Expect = 1e-23 Identities = 29/133 (21%), Positives = 65/133 (48%), Gaps = 1/133 (0%) Query: 3 KILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLE 62 IL+ DD+ I ++ L++ GYD+ + DL++ D+++P+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 VAKEIRKT-SHVPIIMLSAKDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTET 121 + I+K +P++++SA+++ + E GA DY+ KPF EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 IETAVAEENASSG 134 + + +++ Sbjct: 125 RPSKLEDDSQDGM 137
>PF06580#Sensor histidine kinase Length = 349 Score = 44.5 bits (105), Expect = 5e-07 Identities = 30/187 (16%), Positives = 72/187 (38%), Gaps = 34/187 (18%) Query: 253 DETNRMMRMISDLL--NLSRIDNQVTQLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVY 310 + M+ +S+L+ +L + + LA E+T +++ +F +++ ++ Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQF---EDRLQFENQIN 247 Query: 311 EIVRDYPITSVWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQG 370 + D + + ++ ++EN + + I P GGKI ++ + + + + + G Sbjct: 248 PAIMDVQVPPMLVQT-------LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG 300 Query: 371 LGIPKTDLPLIFDRFYRVDKARSRAQGGTGLGLAIAKEIIKQHHGF---IWAKSDYGKGS 427 K + TG GL +E ++ +G I GK Sbjct: 301 SLALKNT------------------KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV- 341 Query: 428 TFTIVLP 434 +++P Sbjct: 342 NAMVLIP 348
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 52.4 bits (125), Expect = 9e-09 Identities = 52/351 (14%), Positives = 117/351 (33%), Gaps = 13/351 (3%) Query: 151 NSKPEERRAIFEEAAGVLKYKTRKKETQI-----KLNQTQDNLDRLEDIIYELDTQLAPL 205 N+ + + + LK + ++ KL + +L I EL+ + A L Sbjct: 66 NNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADL 125 Query: 206 EKQAKVAKQFLELDANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSM 265 EK + + ++ L + R+ +AL + AK +++ Sbjct: 126 EKA----LEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTL 181 Query: 266 EEDYQKFKQKKQVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHL 325 E + + ++ L + + + I LE + + + A Sbjct: 182 EAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFS 241 Query: 326 EQLQEQLDGFQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEF 385 ++ +AE+ + +++ L S ++ ++ L + Sbjct: 242 TADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKAD-- 299 Query: 386 VLLMQKEAALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQK 445 L + L+ +L+ LD ++A++ E+Q L + Q + A + Sbjct: 300 --LEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASR 357 Query: 446 EQVEMLLQNYQKGDKRVQELERDYQLNQERLFDLLDQKKGKEARKASLESI 496 E + L +QK +++ + E Q + L + KK E S Sbjct: 358 EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSK 408
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.7 bits (90), Expect = 4e-05 Identities = 28/141 (19%), Positives = 59/141 (41%), Gaps = 13/141 (9%) Query: 52 SVIGVLFNLFGGVIADSFKR----KKIIITTNILCGTACLVLSFLTKEQWLVYAIVLTNV 107 + G+L +L +I ++ ++ I GT ++L+F T W+ + I+ V Sbjct: 253 AAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT-RGWMAFPIM---V 308 Query: 108 ILAFMSAFSSPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYKLLGIHGV 167 +LA P+ +A V ++ QL L +++ + P++ +Y + Sbjct: 309 LLAS-GGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA----ASI 363 Query: 168 LLLDGLSFLIAALLISFILPV 188 +G +++ A L LP Sbjct: 364 TTWNGWAWIAGAALYLLCLPA 384
>PF06580#Sensor histidine kinase Length = 349 Score = 26.0 bits (57), Expect = 0.021 Identities = 7/45 (15%), Positives = 19/45 (42%) Query: 29 LFLAIAIFGMMVTVSYFSYRDARQYYESQITGLRTQLSRTQKQLK 73 + + + M ++ YF + + Y +++I + + QL Sbjct: 120 IIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLM 164
>PRPHPHLPASEC#Prokaryotic zinc-dependent phospholipase C signature. Length = 398 Score = 31.1 bits (70), Expect = 0.006 Identities = 32/173 (18%), Positives = 63/173 (36%), Gaps = 12/173 (6%) Query: 100 NKIRQKEPKSVDDNLKLLVNSFGNELSSYLYGADWSDTKYDLAVEIINKHDVFSGYKQTE 159 N + + EP+SV NL++L +EL D+ YDL + D + + + Sbjct: 52 NDLSKNEPESVRKNLEIL-KENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDN 110 Query: 160 TYKKADKPYDEGELEKNKKLTQLEQLQQLGRLQQLEQLQQLGRLQQLGRLEQ-LEPTNYS 218 ++ A D GE + K Q G +Q + G ++ P N + Sbjct: 111 SWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEA-MHYFGDIDTPYHPANVT 169 Query: 219 ---------YEAFSDIEDAIFYLDPPYENTTQKSYKGDFNSQAFYDWAFGMSK 262 +E F++ + ++ T + Y ++ F W+ ++ Sbjct: 170 AVDSAGHVKFETFAEERKEQYKINTAGCKTNEDFYADILKNKDFNAWSKEYAR 222
>SSPAMPROTEIN#Salmonella surface presentation of antigen gene type M signature. Length = 147 Score = 28.9 bits (64), Expect = 0.036 Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 6/65 (9%) Query: 331 ERINALENNQKVITNNQKQFELNLPKYLNDINGKRVWYEKPDDNIEHKIGDYWFEKNGKY 390 E I AL Q ++ K EL + + I KR EK + + K YW K G Y Sbjct: 66 EEIYALLRKQSIVRRQIKDLELQIIQ----IQEKRSELEKKREEFQEK-SKYWLRKEGNY 120 Query: 391 QRTWI 395 QR WI Sbjct: 121 QR-WI 124
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 563 bits (1452), Expect = 0.0 Identities = 336/336 (100%), Positives = 336/336 (100%) Query: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL 60 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL Sbjct: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL 60 Query: 61 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI 120 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI Sbjct: 61 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI 120 Query: 121 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA 180 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA Sbjct: 121 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA 180 Query: 181 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA 240 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA Sbjct: 181 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA 240 Query: 241 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQID 300 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQID Sbjct: 241 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQID 300 Query: 301 GNLKLKNPTADDHAATKAYVDSEVKKLKALLMDKQV 336 GNLKLKNPTADDHAATKAYVDSEVKKLKALLMDKQV Sbjct: 301 GNLKLKNPTADDHAATKAYVDSEVKKLKALLMDKQV 336
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.6 bits (77), Expect = 0.002 Identities = 27/145 (18%), Positives = 51/145 (35%), Gaps = 21/145 (14%) Query: 158 RLSSSYQSGINGLKAQLANDKI---GLQAEIQATAQGLSQKYDNELRQLSAKITTTSSGT 214 RL+S + + + Q ++ +AE T +Y+N R +++ SS Sbjct: 186 RLTSLIKEQFSTWQNQKYQKELNLDKKRAERL-TVLARINRYENLSRVEKSRLDDFSSLL 244 Query: 215 TEAYESKLAGLRAEFTRSNQGMRIELESQISGLRAVQQSTTSQISQEIRDRTGAVSRVQQ 274 + +K A L E E++ + SQ+ Q + A Q Sbjct: 245 HKQAIAKHAVL-------------EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL 291 Query: 275 DLESYQR----RLQDAEDNYSSLTH 295 + ++ +L+ DN LT Sbjct: 292 VTQLFKNEILDKLRQTTDNIGLLTL 316
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 31.3 bits (71), Expect = 0.003 Identities = 17/76 (22%), Positives = 32/76 (42%), Gaps = 1/76 (1%) Query: 36 SYQDFLDVLLSLFQFVVIIFVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIE 95 S + ++ L S+ + VV++ +L + NL +L T L +L + +I Sbjct: 133 SIKSLVEFLKSILK-VVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVIC 191 Query: 96 MTLLVLILIFDVLLQK 111 V+I I D + Sbjct: 192 TVGFVVISIADYAFEY 207
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.4 bits (105), Expect = 6e-07 Identities = 21/112 (18%), Positives = 45/112 (40%), Gaps = 13/112 (11%) Query: 170 QQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVE-----VNNDIDPSSKNSQTLV 224 +L+ D E+ K + +V+ + VS V + + ++TL+ Sbjct: 302 DKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT----AETLM 357 Query: 225 HVATEGQ-LQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEW---TGKISYVS 272 + E L+V + D+ + VGQ+ IK + + + GK+ ++ Sbjct: 358 VIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN 409 Score = 37.1 bits (86), Expect = 1e-04 Identities = 24/185 (12%), Positives = 53/185 (28%), Gaps = 29/185 (15%) Query: 21 ITLVLIITGVVLWKQQQNTLTADIAKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFD 80 ++ + + + + V+ G + S S +K + + Sbjct: 62 YFIMGFLVIAFIL--------SVLG--QVEIVATANGKLTHSGR-SKEIKPIENSIV--- 107 Query: 81 ANKGNDATVTVKIGDQVTQGQQLVQYNTTTA-------QSAYDTAVRSLNKIGRQINHLK 133 + VK G+ V +G L++ A QS+ A + ++ Sbjct: 108 ------KEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIE 161 Query: 134 TYGVPAV--STETNKDEATGEETTTTVQPSAQQNANYKQQLQDLNDAYADAQAEVNKAQI 191 +P + E + EE +Q + ++ Q +AE Sbjct: 162 LNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLA 221 Query: 192 ALNDT 196 +N Sbjct: 222 RINRY 226
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 35.5 bits (81), Expect = 3e-04 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 31 SGSQTDKLVIYNWGDYIDPALLKKFTKETGVEVQYETFDSNEAMYTKIKQGGTTYDIAVP 90 S + V+ N+ YI P LL++ + + + T+ SNE + TY +AV Sbjct: 21 SSCGSTTFVLANFESYISPLLLER--VQEKHPLTFLTYPSNEKLINGF--ANNTYSVAVA 76 Query: 91 SDYTIDKMIKENLLNKLDKSKL 112 S Y + ++I+ +LL+ +D S+ Sbjct: 77 STYAVSELIERDLLSPIDWSQF 98
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.5 bits (170), Expect = 5e-16 Identities = 23/131 (17%), Positives = 51/131 (38%), Gaps = 2/131 (1%) Query: 3 VLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTDYAIDLILLDIHITDGNGI 62 +L+ +DD + + L + + + + + + DL++ D+ + D N Sbjct: 6 ILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 QFLEKLRAQHIPCEVIIISAANDGNIIRDGFHLGIIDYLIKPFTFERFQESIQQFVTHRE 122 L +++ V+++SA N G DYL KPF I + + + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 123 HLANQQLEQAQ 133 ++ + +Q Sbjct: 124 RRPSKLEDDSQ 134
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 65.8 bits (160), Expect = 5e-14 Identities = 76/299 (25%), Positives = 120/299 (40%), Gaps = 45/299 (15%) Query: 36 DLKVAMVTDTGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAV 95 LK ++TD G +DDKSFNQSA+E L++ + K TG + S + + ++A+ Sbjct: 61 KLKPVLITDEGKIDDKSFNQSAFEALKA------INKQTGIEINNVEPSSNFESAYNSAL 114 Query: 96 SGGYQLIYGIGFALKDAIAKAAGD------NEGVKFVIIDDIIEGKDNV-ASVTFADHEA 148 S G+++ GF + +I + +K + ID IE + S+ F E+ Sbjct: 115 SAGHKIWVLNGFKHQQSIKQYIDAHREELERNQIKIIGIDFDIETEYKWFYSLQFNIKES 174 Query: 149 AYLAGIAAAKTTKTK-----TVGFVGGMEGTVITRFEKGFEAGVKS---------VDDTI 194 A+ G A A + V GG +T F +GF G+ + T Sbjct: 175 AFTTGYAIASWLSEQDESKRVVASFGGGAFPGVTTFNEGFAKGILYYNQKHKSSKIYHTS 234 Query: 195 QVKVDYAGSFGDAAKGKTIAAAQYAAGADVIYQAAGG---TGAGVFNEAKAINEKRSEAD 251 VK+D +G I + ADV Y G F + N+ + Sbjct: 235 PVKLD-SGFTAGEKMNTVINNVLSSTPADVKYNPHVILSVAGPATFETVRLANKGQ---- 289 Query: 252 KVWVIGVDRDQKDEGKYTSKDGKEANFVLASSIKEVGKAVQLINKQVADKKFPGGKTTV 310 +VIGVD DQ +D +L S +K + +AV + +K G K V Sbjct: 290 --YVIGVDSDQG-----MIQDKDR---ILTSVLKHIKQAVYETLLDLILEKEEGYKPYV 338
>PF06580#Sensor histidine kinase Length = 349 Score = 39.1 bits (91), Expect = 2e-05 Identities = 15/75 (20%), Positives = 31/75 (41%), Gaps = 5/75 (6%) Query: 312 YGKIFYFQNQVNRSLRMDKALLKQLITILFDNAIKY----TDKNGIIEIIVKTTDKNLLI 367 + F+NQ+N ++ D + L+ L +N IK+ + G I + + + + Sbjct: 236 FEDRLQFENQINPAIM-DVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTL 294 Query: 368 SVIDNGPGITDEEKK 382 V + G K+ Sbjct: 295 EVENTGSLALKNTKE 309
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.0 bits (67), Expect = 0.042 Identities = 23/127 (18%), Positives = 40/127 (31%), Gaps = 27/127 (21%) Query: 216 AFSKDYQKRVTQNQAHLDNLLKDNGQ-----KRYDDLQNQYDLALKNGRAALAKETVKLA 270 FS ++ +A L + + + +K A A + A Sbjct: 239 NFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKA 298 Query: 271 ASEENLTFLEVS---------ALQEAKHQIEQGKQALAKEEKQ------------LEQVQ 309 E L + A +EAK Q+E Q L +E+ + L+ + Sbjct: 299 DLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKL-EEQNKISEASRQSLRRDLDASR 357 Query: 310 ATKDKLE 316 K +LE Sbjct: 358 EAKKQLE 364
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.5 bits (76), Expect = 6e-04 Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Query: 32 KGELVVIL-GASGAGKSTVLNILGGMD-TVDAGQVIIDGKD 70 K + V+L G G GKST++N L G+D D I GKD Sbjct: 594 KFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 40.8 bits (95), Expect = 8e-07 Identities = 13/48 (27%), Positives = 26/48 (54%) Query: 4 RHTETKAYVKTALITLLTEQSFETLTVSDLTKKAGINRGTFYLHYTDK 51 ET+ ++ + L ++Q + ++ ++ K AG+ RG Y H+ DK Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDK 55
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.015 Identities = 19/109 (17%), Positives = 32/109 (29%), Gaps = 15/109 (13%) Query: 19 LVGLVLLSVFGWVVGITGGYIYLPYSYRWLSWGMDSFPNLLDSALSYYYFWTALVLFVIT 78 ++ + +S+ G V +T Y WL M A V+ Sbjct: 42 MIFNIAISLMGLV--LTHAYRSFIKRQGWLKLNMGQI---------ILRVLPACVVIG-- 88 Query: 79 FLALLVIILYPRIYTEVQLRHKNKKGTLLLKKSAIESYVATAIQTAGLM 127 + + R+ + K TL L S I + V + L Sbjct: 89 MVWFVANTSIWRLLAFIN--TKPVAFTLPLALSIIFNVVVVTFMWSLLY 135
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 51.1 bits (122), Expect = 8e-10 Identities = 38/185 (20%), Positives = 76/185 (41%), Gaps = 35/185 (18%) Query: 100 YNFIISSNLHPSVEGKFNVGDNVDVFGL--ALSAEVFSKDQIHSINGGLV---------- 147 Y+ + + L+ + K+ + VDV+G ++ SKD + + GG Sbjct: 88 YDKVKTELLNEDLAKKYK-DEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHE 146 Query: 148 --KVNERKGAGKTIYMNVFIDGHKKDDTSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIK 205 + + + + V+ + K +T +++ +K VT QE+D++ R L ++ Sbjct: 147 GNHFDNGNL--QNVLVRVYEN---KRNTISFEVQTDKKSVTAQELDIKARN--FLINKKN 199 Query: 206 LYQYD-SKVLSGNWEFHGSGEKEEGADLFKYPD-----------YRYNNLIDIDKKSHID 253 LY+++ S +G +F + D+ P Y N +D K I+ Sbjct: 200 LYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVD-SKSVKIE 258 Query: 254 VYLFT 258 V+L T Sbjct: 259 VHLTT 263
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 54.9 bits (132), Expect = 3e-11 Identities = 52/218 (23%), Positives = 92/218 (42%), Gaps = 29/218 (13%) Query: 35 LKNIYTKDVINRTNMKITKK-IGTQLIFNTNEKTRVWDDDNYNKVISSNVSPAQERRFKE 93 +K +Y ++ T +K K + LI+N ++K NY+KV + ++ +++K+ Sbjct: 51 MKYLYDDHYVSATKVKSVDKFLAHDLIYNISDK----KLKNYDKVKTELLNEDLAKKYKD 106 Query: 94 EEVDIYALIKSYSVICKEQYNYVDG--------GLIRTSDREKLDSTIYMNIFGEQIPLK 145 E VD+Y + + N G I + D+ N+ K Sbjct: 107 EVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENK 166 Query: 146 EQS-KYKITFQNKFVTFQEIDVRLRKSLMSDNRIKLYEHN-SICKKGYWGIHYKDNTTKF 203 + +++ K VT QE+D++ R L+ N+ LYE N S + GY + T + Sbjct: 167 RNTISFEVQTDKKSVTAQELDIKARNFLI--NKKNLYEFNSSPYETGYIKFIENNGNTFW 224 Query: 204 TDLFTHPN-----------YTDNETIDMSKVSHFDVYL 230 D+ P Y DN+T+D SK +V+L Sbjct: 225 YDMMPAPGDKFDQSKYLMMYNDNKTVD-SKSVKIEVHL 261
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 95.9 bits (238), Expect = 3e-26 Identities = 46/123 (37%), Positives = 64/123 (52%), Gaps = 8/123 (6%) Query: 23 SLTAAQAILESGWGKHA-------PHNALFGIKADSSWTGKSFDTKTQEEYQPGVVTDIV 75 L AQA LESGWG+ P LFG+KA +W G + T E Y+ G + Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230 Query: 76 DRFRAYGSWDESILDHGKFLNDNPRYKAVVGETDYKKACHAIKDAGYATASGYAELLIQI 135 +FR Y S+ E++ D+ L NPRY AV ++ A++DAGYAT YA L + Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290 Query: 136 IKE 138 I++ Sbjct: 291 IQQ 293
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 553 bits (1427), Expect = 0.0 Identities = 260/334 (77%), Positives = 294/334 (88%), Gaps = 2/334 (0%) Query: 1 MTETIPLRVQFKRMTAKEWASSAVILLEGEIGFETDTGYAKFGDGKSRFSELKYLNKPDL 60 MTETIPLRVQFKRMTA+EW S VILLE EIGFETDTGYAKFGDGK++FS+LKYLNKPDL Sbjct: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL 60 Query: 61 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLSLTGGIVTGQLRLKPN-SGI 119 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKL+L GG++TGQL+ KPN SGI Sbjct: 61 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI 120 Query: 120 EKSSSTGGAINIDMSKSKGAAMVMYTNKDTTDGPLMILRSNKDTFDQSVQFVDYRGKTNA 179 + SSS GGAINIDMSKS+GA +V+Y+N DT+DGPLM LR+ K+TF+QS FVDY GKTNA Sbjct: 121 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA 180 Query: 180 VNIVMRQPSTPNFSSALNITSANEGGSAMQLRGSEEALGTLKITHENPSLEANYDKNAAA 239 VNI MRQP+TPNFSSALNITS NE GSAMQ+RG E+ALGTLKITHENP++EANYD+NAAA Sbjct: 181 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA 240 Query: 240 LSIDIVKKTNGA-GTAAQGIYINSTSGTTGKLLRIRNKNKDKFYVNPDGGFHSYADSIVD 298 LSIDIVKK G GTAAQGIYINSTSGTTGKLLRIRN DKFYV DGGF++ S +D Sbjct: 241 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQID 300 Query: 299 GNLTVKNPTSNEHAATKKYVDEKIAELKKLIPKK 332 GNL +KNPT+++HAATK YVD ++ +LK L+ K Sbjct: 301 GNLKLKNPTADDHAATKAYVDSEVKKLKALLMDK 334
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 29.8 bits (66), Expect = 0.019 Identities = 25/100 (25%), Positives = 55/100 (55%), Gaps = 14/100 (14%) Query: 389 QNMIDESLETITGLGMT------FQEFLQDIEKRIETGKKEMEDNWRKVNLEFDNFKKKV 442 QN +L + G+T +Q+F+Q +EK I ++++ +KV++ +++++K Sbjct: 46 QNEYRNNLNSDMSAGITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREK- 104 Query: 443 EQEGLQFNTLKEQIKE----VDERID-KELEEF--RATLK 475 +Q + TL+E+ + R+D K+++EF RA ++ Sbjct: 105 KQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMR 144
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 32.2 bits (73), Expect = 0.009 Identities = 63/330 (19%), Positives = 115/330 (34%), Gaps = 44/330 (13%) Query: 192 ISAVIQSLTGVITAVFNGIATVISSVGSAIKDVLTGLGI--AFEGFGNGVK-SALEGVGA 248 ++ I ++S+ + + L+ + I + +G S+ E A Sbjct: 124 AGNILGGGAENIGDNLGKAGGILSTFQNFLGTALSSMKIDELIKKQKSGGNVSSSELAKA 183 Query: 249 VIESFGSAVRNVLDGVANILDSMGTAALNAGRGVKEMAKGIKMLVDLSLGDLVATLAAVA 308 IE V V N+ +S G + K + +G+ + L Sbjct: 184 SIELINQLVDTVASLNNNV-NSFSQQLNTLGSVL-SNTKHLN-----GVGNKLQNL---- 232 Query: 309 SGLGKMASSAGEMTTLGSAMSKVANGMTRLATSATIAITGLTVFATTMATIKTAVATLPP 368 L + + ++ + SA+S A + T A G+ + + + ++ Sbjct: 233 PNLDNIGAGLDTVSGILSAISASFILSNADADTRTKAAAGVELTTKVLGNVGKGISQYII 292 Query: 369 VLTMAASGFTTFTTQAVAAVTGLAAINAPITMFKAQLMAITPALAQAGAGFAAFVAQSST 428 A T+ AA GL A A +AI+P L+ +A Sbjct: 293 AQRAAQGLSTS------AAAAGLIA--------SAVTLAISP-LSFLS------IADKFK 331 Query: 429 FSTGLASAGPTIAAFNANLMSLSAT----TGALVASIVGLSAVLSVVLADFSQIGASATA 484 + + + SL A TGA+ AS+ +S VL+ V + S A+ T+ Sbjct: 332 RANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASLTTISTVLASVSSGIS--AAATTS 389 Query: 485 TVGQ-IQAFASSTTVVSSAF--ASMQSMIQ 511 VG + A + T + S AS Q+M + Sbjct: 390 LVGAPVSALVGAVTGIISGILEASKQAMFE 419
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 33.2 bits (75), Expect = 0.003 Identities = 48/199 (24%), Positives = 80/199 (40%), Gaps = 10/199 (5%) Query: 63 EARKRASELDISAYQKKAKELVAKAEKLRKEGRTVTRDDFTHQENADMSIYNLAMKTNAL 122 E +K+A E + A ++ K K EK RKE R R + + NA + NL+ N Sbjct: 142 EEQKKALEKEKEAKEQAQKAQKDKREK-RKEERAKNRANLENLTNAMSNPQNLSNNKNLS 200 Query: 123 ELLRLNIDLE---------MQELANGEHKLTKKFLDEGYRKETEFQAGLLGLSVASQASV 173 EL++ + E MQE A + L++ +E Q +S+ + S Sbjct: 201 ELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEEAVRQRAKDKISIKTDKSQ 260 Query: 174 KSLADAVINANFKGAKWSDNIWDRQDKLRSIISQSVQSAILRGKNGLTIARDIRREFDVS 233 KS D I + + W N+ R +K + LT+ + + +VS Sbjct: 261 KSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVS 320 Query: 234 ASYAKRLAITEHARVQMEV 252 + + L E A+ Q E+ Sbjct: 321 SVIEEELKKREEAKRQREL 339
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 27.6 bits (61), Expect = 0.013 Identities = 13/75 (17%), Positives = 30/75 (40%), Gaps = 6/75 (8%) Query: 51 DNLDDYVLMQSTGLKDKNGVKIFEGDVVKLQYTITSDLEFFKVNQFRGGSW-RIDNRRRG 109 DN + Y + + K + + V Y +T + + + G+W R+ N++ Sbjct: 228 DNDEHYDPGKRITYRSKVKDQNYYSVAVNAGYYVTPNAKVYV-----EGAWNRVTNKKGN 282 Query: 110 SELWLRNDDCEVVGN 124 + L+ N++ Sbjct: 283 TSLYDHNNNTSDYSK 297
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 92.1 bits (228), Expect = 5e-23 Identities = 44/125 (35%), Positives = 63/125 (50%), Gaps = 8/125 (6%) Query: 23 SLTAAQTILESGWGKHA-------PHNALFGIKADSSWTGKSFDTKTQEEYQAGVVTDIV 75 L AQ LESGWG+ P LFG+KA +W G + T E Y+ G + Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230 Query: 76 DRFRAYDSWTDSIIDHGKFLNDNPRYQAVIGETDYKKACHAIKDAGYATASGYAELLIQL 135 +FR Y S+ +++ D+ L NPRY AV ++ A++DAGYAT YA L + Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290 Query: 136 IEEND 140 I++ Sbjct: 291 IQQMK 295
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 558 bits (1438), Expect = 0.0 Identities = 282/334 (84%), Positives = 307/334 (91%), Gaps = 1/334 (0%) Query: 1 MTETIPLRVQFKRMTAEEWARSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKLDL 60 MTETIPLRVQFKRMTAEEW RSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNK DL Sbjct: 1 MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDL 60 Query: 61 DAFAQKKETNSKITKLESNKADKNAVYLKAESNAKLDEKLSLTGGIVTGQLQFKPN-SGI 119 AFAQK+ETNSKITKLES+KADKNAVYLKAES +LD+KL+L GG++TGQLQFKPN SGI Sbjct: 61 GAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGI 120 Query: 120 KPSSSVGGAINIDMSKSKGAGIVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYSGKTNA 179 KPSSSVGGAINIDMSKS+GAG+VVYSNNDTSDGPLMSLRTGKETFN+SALFVDYSGKTNA Sbjct: 121 KPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNA 180 Query: 180 VNIAMRQPSTPNFSSALNITSGNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENAAA 239 VNIAMRQP+TPNFSSALNITSGNENGSAMQ+RG EKALGTLKITHENPNVEA YDENAAA Sbjct: 181 VNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAA 240 Query: 240 LSIDIVKKQKGGKGTAAQGIYINSTSGTAGKMLRIRNKNKDKFYVGPDGDFWSCASSIVD 299 LSIDIVKKQKGGKGTAAQGIYINSTSGT GK+LRIRN DKFYV DG F++ +S +D Sbjct: 241 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQID 300 Query: 300 GNLTVKDPTSGKHAATKDYVDEKIAELKKLILKK 333 GNL +K+PT+ HAATK YVD ++ +LK L++ K Sbjct: 301 GNLKLKNPTADDHAATKAYVDSEVKKLKALLMDK 334
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.026 Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 119 KSEETEDYITDYVEGLVAAGLGAYQEDNLHMKVKLRS 155 K E +D YVE A Y E+N ++K+RS Sbjct: 48 KQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRS 84
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 151 bits (383), Expect = 1e-49 Identities = 49/154 (31%), Positives = 85/154 (55%), Gaps = 4/154 (2%) Query: 19 KKEASKNEKT--KAVLNQAVADLSVAASIVHQVHWYMRGPGFLYLHPKMDELLDSLNANL 76 K E +K +T + LN +++ + S +H+ HWY++GP F LH K +EL D + Sbjct: 2 KTENAKTNQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETV 61 Query: 77 DEMSERLITIGGAPYSTLAEFSKHSKLDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGL 136 D ++ERL+ IGG P +T+ E+++H+ + + + + ++ + LV Y +SS + + Sbjct: 62 DTIAERLLAIGGQPVATVKEYTEHASITDGGN--ETSASEMVQALVNDYKQISSESKFVI 119 Query: 137 DITDEEGDAGTNDLFTAAKTEAEKTIWMLQAERG 170 + +E D T DLF E EK +WML + G Sbjct: 120 GLAEENQDNATADLFVGLIEEVEKQVWMLSSYLG 153
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 30.9 bits (70), Expect = 0.003 Identities = 42/160 (26%), Positives = 59/160 (36%), Gaps = 25/160 (15%) Query: 78 SLIIILWASMVHWVSASYCYLLLFSLLFSLF--DWRSQ------EYPFILWLFSFVSLLL 129 +L+ + A + + LLL +L +L D P + F L Sbjct: 118 ALLSVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGG 177 Query: 130 FYSIN---------YLSLILLLLGLLAHLRPFSIGAGDFFYLASLALVLDLTSLIWLIQL 180 F S+ YL L L +G GDF LA+L L +L ++ L Sbjct: 178 FVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLL 237 Query: 181 ASLAGITACLLL-------GIKRIPFIPYLSFGLFWIVLL 213 +SL G + L K IPF PYL+ WI LL Sbjct: 238 SSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIA-GWIALL 276
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 31.7 bits (72), Expect = 0.004 Identities = 13/76 (17%), Positives = 34/76 (44%), Gaps = 9/76 (11%) Query: 50 LAQSLKTKKNQLVGLLLPDISNPFF-PRLARGAEEYLKEKGYRVMLGNISDSEALEE--- 105 +++ L +Q+VG+ D N ++ L + E L + G++ +++D E + + Sbjct: 16 VSKRLLEAGHQVVGI---DNLNDYYDVSLKQARLELLAQPGFQFHKIDLADREGMTDLFA 72 Query: 106 --EYVHVLLQSNAAGI 119 + V + + + Sbjct: 73 SGHFERVFISPHRLAV 88
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 153 bits (388), Expect = 2e-50 Identities = 58/157 (36%), Positives = 94/157 (59%), Gaps = 2/157 (1%) Query: 5 IGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKKSYFKLEVRKAMLTQALADFT 64 +Y GSFDP+T GHLDI++R LFDQ+YV + NP K+ F ++ R + +A+A Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 65 NVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEENLEYFNHLLAPNIETVYLISRN 124 N V + E L ++ A++ + ++RGLR +DFE E + N LA ++ETV+L + Sbjct: 62 NAQVDSF-EGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTST 120 Query: 125 KWQALSSSRVRELIHFQSSLEGLVPQSVIAQV-EKMN 160 ++ LSSS V+E+ F ++E VP V A + ++ + Sbjct: 121 EYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFH 157
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 404 bits (1039), Expect = e-144 Identities = 140/315 (44%), Positives = 203/315 (64%), Gaps = 6/315 (1%) Query: 3 KQKIVVALGGNAIL--STDASAKAQQEALMSTSKSLVKLIKEGHEVIVTHGNGPQVGNLL 60 +++V+ALGGNA+ S + + + T++ + ++I G+EV++THGNGPQVG+LL Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61 Query: 61 LQQAAADSEKN-PAMPLDTCVAMTEGSIGFWLVNALDNELQAQGIQKEVAAVVTQVIVDA 119 L A + PA P+D AM++G IG+ + AL NEL+ +G++K+V ++TQ IVD Sbjct: 62 LHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDK 121 Query: 120 KDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWRKVVPSPKPVGIKEANVIRS 179 DPAF+NPTKP+GPF EE AK+ E G KED+GRGWR+VVPSP P G EA I+ Sbjct: 122 NDPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKK 181 Query: 180 LVDSGVVVVSAGGGGVPVVEDATSKSLTGVEAVIDKDFASQTLSGLVDADLFIVLTGVDN 239 LV+ GV+V+++GGGGVPV+ + + GVEAVIDKD A + L+ V+AD+F++LT V+ Sbjct: 182 LVERGVIVIASGGGGVPVILED--GEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNG 239 Query: 240 VYINFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLPKVEAAIAFVENKPNAKAIITSLE 299 + + + L EV V ++++Y + F GSM PKV AAI F+E +AII LE Sbjct: 240 AALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEW-GGERAIIAHLE 298 Query: 300 NIDNVLSANAGTQII 314 L GTQ++ Sbjct: 299 KAVEALEGKTGTQVL 313
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.8 bits (80), Expect = 0.002 Identities = 11/73 (15%), Positives = 27/73 (36%), Gaps = 6/73 (8%) Query: 805 YLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQ 864 + +L E + EL ++ +L+ + ++ +AK E + + + Sbjct: 248 AIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEI------LSAKEEYQLVTQLFKNEIL 301 Query: 865 AKYDATQERIAEM 877 K T + I + Sbjct: 302 DKLRQTTDNIGLL 314
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.1 bits (208), Expect = 2e-19 Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 6/133 (4%) Query: 3 KVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALTYLTQYPVDVMISDVTMPGMT 62 +L+ DD+ I L + G++V + ++ D++++DV MP Sbjct: 5 TILVADDDAAIRTVLNQAL--SRAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQAKMKQFKDC 122 DL+ K P L L++S F KA E YL KP D L + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFD---LTELIGIIGRA 118 Query: 123 LDAQQAESIRQEA 135 L + + E Sbjct: 119 LAEPKRRPSKLED 131
>PF06580#Sensor histidine kinase Length = 349 Score = 181 bits (462), Expect = 2e-54 Identities = 71/324 (21%), Positives = 133/324 (41%), Gaps = 34/324 (10%) Query: 250 LSKAYRMQYNRSGDLLAYVAVRKSYLLAEAVRTVFVYGLVSLLLAWLLLQLL-FRVFRNY 308 L+ AYR R G L + + A + + V+ W LL + + Sbjct: 55 LTHAYRSFIKRQG-WLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFT 113 Query: 309 IQQVSEITDTVEMVAAGDLSLTIDNSHMELELYHISEAINQMLASIKAYIDEVYVLEVEQ 368 + I V +V + M LY + +A ID+ + Sbjct: 114 LPLALSIIFNVVVV-----------TFMWSLLYF---GWHFFKNYKQAEIDQWK-MASMA 158 Query: 369 RDAQMRALQSQINPHFLYNTLEYIRMYALSCQQEELADVIYAFASLLRNNI--SQDKMTT 426 ++AQ+ AL++QINPHF++N L IR L + +++ + + L+R ++ S + + Sbjct: 159 QEAQLMALKAQINPHFMFNALNNIRALILE-DPTKAREMLTSLSELMRYSLRYSNARQVS 217 Query: 427 LKEELAFCEKYIYLYQMRYPDSFAYHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRH 486 L +EL + Y+ L +++ D + +I+ +I D+ +P ++Q LVEN HGI Sbjct: 218 LADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQ 277 Query: 487 DNALSIKALDETDHLLIQVLDNGRGISQERLADMEKRLQEHQTTGNSSIGLQNVYLRLFH 546 + +K + + ++V + G L T ++ GLQNV RL Sbjct: 278 GGKILLKGTKDNGTVTLEVENTG-------------SLALKNTKESTGTGLQNVRERLQM 324 Query: 547 HFRDRVSWSMAKEPNGGFIIQIRI 570 + ++++ G + I Sbjct: 325 LYGTEAQIKLSEKQ-GKVNAMVLI 347
>PF05043#Transcriptional activator Length = 493 Score = 54.9 bits (132), Expect = 4e-10 Identities = 30/162 (18%), Positives = 71/162 (43%), Gaps = 7/162 (4%) Query: 3 IEDLMDKERRAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTLLKYIDNLNHLCREQGLAC 62 + DL+ K+ Q LL L+ K +L L N ++ + + ++ + Sbjct: 1 MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIF-- 58 Query: 63 QLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMYCHEHFNITNLSVELMVSEAT 122 + + E + K S + IL +++ +E ++ E +S ++ Sbjct: 59 -HSSTNGIRIINTDDS-DIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSS 116 Query: 123 LNRQLAHLNQLLS---EFDLALSQGRQLGSELQWRYFYFELF 161 L R ++ +N+++ +F+++L+ + +G+E RYF+ + F Sbjct: 117 LYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYF 158
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 40.0 bits (93), Expect = 1e-06 Identities = 15/78 (19%), Positives = 29/78 (37%), Gaps = 3/78 (3%) Query: 69 NQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEFQNKDQE 128 + S ++ +D A + + + E L + D E + YE+ + Sbjct: 134 TEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTRLVIYPDEETPRLAYEVNVRFLTPV 193 Query: 129 ---YSYTIDANSGDIVEK 143 + Y IDA G ++ K Sbjct: 194 PGNWIYMIDAADGKVLNK 211
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 93.6 bits (232), Expect = 1e-23 Identities = 46/123 (37%), Positives = 65/123 (52%), Gaps = 8/123 (6%) Query: 23 SLTAAQAILESGWGKYA-------PHNALFGIKADSSWTGKSFNTKTQEEYQPGIVTDIV 75 L AQA LESGWG+ P LFG+KA +W G T E Y+ G + Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230 Query: 76 DRFRAYDSWEDSIADHGQFLVDNPRYKAVIGEADYKKACHAIKDAGYATASGYAELLIQL 135 +FR Y S+ ++++D+ L NPRY AV A ++ A++DAGYAT YA L + Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290 Query: 136 IEE 138 I++ Sbjct: 291 IQQ 293
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.6 bits (95), Expect = 2e-05 Identities = 28/186 (15%), Positives = 61/186 (32%), Gaps = 12/186 (6%) Query: 154 KSLLEQKTAQLGLTVDGLKLDLNKANKQTASLQASIDGLRQDYRDADRQLSANYQAGLNG 213 SLL+ + Q + ++LNK + + + ++ L + Sbjct: 141 SSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN 200 Query: 214 LKAQLTNDKIGLQAEIQATAQGLSQKYDNELRQLSAKITTTSSGTTEAY--ENKLEGLRA 271 K Q + +AE T +Y+N R +++ SS + ++ + Sbjct: 201 QKYQKELNLDKKRAERL-TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQEN 259 Query: 272 EFTRSNQGMRT------ELESQISGLRAVQQSTASQISQEIRNREGAVSRVQQNLASYQR 325 ++ + +R ++ES+I + Q EI + + N+ Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL---DKLRQTTDNIGLLTL 316 Query: 326 RLQSAE 331 L E Sbjct: 317 ELAKNE 322
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 27.8 bits (61), Expect = 0.026 Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Query: 71 QAEAKVEKYKETIRRAMELSQKKKVDAGMFKVSLRKSKKVEILDETKIPLDYMQEKIEYK 130 + A E Y E+ + ++K K + FK S+ K E +ET + Q+ ++ Sbjct: 30 EVNAMNEHYTESDIKRNHKTEKNKTEKEKFKDSINNLVKTEFTNETLDKIQQTQDLLKKI 89 Query: 131 PMKS-EISKALKSGIDISGVELIETESLQ 158 P EI L I + ++L+E + LQ Sbjct: 90 PKDVLEIYSELGGEIYFTDIDLVEHKELQ 118
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 36.4 bits (84), Expect = 3e-04 Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 11/140 (7%) Query: 207 LSNITIKNVDTYRNKLAKTFETLNKLFEIDGVKISKELLTSKLKQL-------DILYKYQ 259 L I + N++ K TL K + D K+ ELLT+ + L ++ Y Sbjct: 304 LQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTANIYALKKGLSHIELANYYS 363 Query: 260 KQIEIEKELLKAQKEEIREQQKAEKEIQQAKAKLKKEERQFNNEMSKLLKYLNGAQNEIE 319 + + K L K + Q K+ + K + Q + + L YL I Sbjct: 364 ENYDTVKITLDENKTPSQNVQSYYKKYNKLKKSEEAANEQL-LQNEEELNYLYSVLTNIN 422 Query: 320 QQIYADKIKELEDKIKELEK 339 AD E+E+ KEL + Sbjct: 423 N---ADNYDEIEEIKKELIE 439
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.0 bits (109), Expect = 3e-08 Identities = 21/118 (17%), Positives = 51/118 (43%), Gaps = 6/118 (5%) Query: 2 KILLIDDHRLFAKSIQLLFQQYD-EVDVIDTITSHFNDVTIDLSKYDIILLDINLTNISK 60 IL+ DD + + +V + + + + D+++ D+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI--AAGDGDLVVTDVVM---PD 59 Query: 61 ENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGFVDKNIDPKQLISILKK 118 EN ++ + ++ P L V++++ + +A + GAY ++ K D +LI I+ + Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 29.8 bits (67), Expect = 0.006 Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 11/85 (12%) Query: 1 MKKKERHEKILDILKVDGFIKVKDIIDEM-----NISDMTARRDLDTLADKGLL-IRTHG 54 M K +RH KI +I+ + +++D + N++ T RD+ L L+ + T+ Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKEL---HLVKVPTNN 57 Query: 55 GAQYLDYSSAKDEGHEKTHTEKKVL 79 G+ YS D+ K+ L Sbjct: 58 GSYK--YSLPADQRFNPLSKLKRSL 80
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 29.8 bits (67), Expect = 0.008 Identities = 8/44 (18%), Positives = 17/44 (38%), Gaps = 2/44 (4%) Query: 227 INGYKVTSWNDLTEAV-DLATRD-LGPSQTIKVTYKSHQRLKTV 268 + ++ L E + DL +D + +Q+LK + Sbjct: 80 FDITEIGEQYSLKETIQDLCAKDFHQKLKEFTEKTPKNQKLKDL 123
>PF05272#Virulence-associated E family protein Length = 892 Score = 35.0 bits (80), Expect = 6e-04 Identities = 14/56 (25%), Positives = 20/56 (35%), Gaps = 9/56 (16%) Query: 34 IVFVGPSGCGKSTTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALY 89 +V G G GKST + + GL+ S+ IG +D Y Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG---------TGKDSYEQIAGIVAY 645
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.7 bits (77), Expect = 7e-04 Identities = 10/30 (33%), Positives = 19/30 (63%) Query: 229 ALWSEHGNLVQTAQRLYIHRNSLQYKLDKF 258 AL + GN ++ A L ++RN+L+ K+ + Sbjct: 444 ALTATRGNQIKAADLLGLNRNTLRKKIREL 473
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 793 bits (2049), Expect = 0.0 Identities = 388/440 (88%), Positives = 413/440 (93%) Query: 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGYEWLLDRPSVNNSQLVVSMAGIVEGTDKKVF 60 MKNYLSFGMFALLFALTFGTV VQAIAG EWLLDRPSVNNSQLVVS+AG VEGT++ + Sbjct: 1 MKNYLSFGMFALLFALTFGTVNSVQAIAGPEWLLDRPSVNNSQLVVSVAGTVEGTNQDIS 60 Query: 61 INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQERLIANVHSN 120 + FFEIDLTS+PAHGGKTEQGLSPKSKPFATD+GAM HKLEKADLLKAIQE+LIANVHSN Sbjct: 61 LKFFEIDLTSRPAHGGKTEQGLSPKSKPFATDSGAMSHKLEKADLLKAIQEQLIANVHSN 120 Query: 121 DGYFEVIDFASDATITDRDDNIYFANQDGSVTLPTQPIQQFLLRGHVRVRPYKEKPIQTP 180 D YFEVIDFASDATITDR+ +YFA++DGSVTLPTQP+Q+FLL GHVRVRPYKEKPIQ Sbjct: 121 DDYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLSGHVRVRPYKEKPIQNQ 180 Query: 181 AKSVDIRYTVQFTPLNPDDDFKPVLKDTKLLKTLAIGDTITSQELLAQAQSILNESHSDY 240 AKSVD+ YTVQFTPLNPDDDF+P LKDTKLLKTLAIGDTITSQELLAQAQSILN++H Y Sbjct: 181 AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKNHPGY 240 Query: 241 TIYERDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYGINKKSGQEEKTNNTDLISEKY 300 TIYERDSSIVTHDNDIFRTILPMDQEFTY +K+REQAY INKKSG E+ NNTDLISEKY Sbjct: 241 TIYERDSSIVTHDNDIFRTILPMDQEFTYRVKNREQAYRINKKSGLNEEINNTDLISEKY 300 Query: 301 YVLKKGEKPYDPFDRSHLKLFTINYVDVNTNKLLKSEQLLTASERNLDFRDLYDPRDKAK 360 YVLKKGEKPYDPFDRSHLKLFTI YVDV+TN+LLKSEQLLTASERNLDFRDLYDPRDKAK Sbjct: 301 YVLKKGEKPYDPFDRSHLKLFTIKYVDVDTNELLKSEQLLTASERNLDFRDLYDPRDKAK 360 Query: 361 LLYNNLDAFGIMDYTLTGKVEDNHDKNNRVVTVYMGKRPEGENASYHLAYDKDRYTEEER 420 LLYNNLDAFGIMDYTLTGKVEDNHD NR++TVYMGKRPEGENASYHLAYDKDRYTEEER Sbjct: 361 LLYNNLDAFGIMDYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEER 420 Query: 421 EVYSYLRYTGTPIPDNPKDK 440 EVYSYLRYTGTPIPDNP DK Sbjct: 421 EVYSYLRYTGTPIPDNPNDK 440
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 126 bits (317), Expect = 5e-33 Identities = 107/457 (23%), Positives = 184/457 (40%), Gaps = 40/457 (8%) Query: 143 IEAIKYRLDSESHLKEELLKQTAELEQRKNAEVDLKSEKKRLEAQIEKVGYDIANKQQEL 202 + K +L E + ELE RK + ++ L Sbjct: 94 LSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 153 Query: 203 EKARSDQKELSESIQKLTSRFKKESDAKQKELDEAKAANKSLSESATKTLARSSKITNEL 262 ++D ++ E F AK K L+ KAA ++ K L + + Sbjct: 154 AARKADLEKALEGA----MNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTAD 209 Query: 263 KDKLAASEKDKNRAFQVSSELANKLHETETSRDKALAESKELADKLAVKTAEAEKLMENV 322 K+ E +K LA + + E + + A+ S + K+ AE L Sbjct: 210 SAKIKTLEAEKA-------ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQ 262 Query: 323 GSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTELEKVKTELAVSE 382 L++ +E A A+I L A+KA +AE A L + ++ +L S Sbjct: 263 AELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASR 322 Query: 383 RLIESGKREIAELEKQKDASDKALAESQANVAELEKQKAASDAKVAELEKEVEAAKAEVA 442 + + E +LE+Q S+ + + ++ + K +A+ +LE++ + ++A Sbjct: 323 EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQ 382 Query: 443 DLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEMLEKKDHANADLQAEIN 502 L+ L E + V+K E +K+ L+K + E K ++K A L+AE Sbjct: 383 SLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAK 442 Query: 503 RLKQELADRIKSLSQGGRASQTNPGSTTAKAG---------------------------- 534 LK++LA + + L++ ++ + AK G Sbjct: 443 ALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETK 502 Query: 535 -QLPSTGESANPFFTIAALTVIAGAGMAVVSPKRKEN 570 QLPSTGE+ANPFFT AALTV+A AG+A V +++EN Sbjct: 503 RQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN 539
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.7 bits (77), Expect = 0.001 Identities = 28/155 (18%), Positives = 46/155 (29%), Gaps = 38/155 (24%) Query: 8 RMRPKTISEVIGQKHLVGEGKIIRRMVE-----ANRLSSMILYGPPGIGKTSIASAIAGT 62 R K + LVG ++ + ++++ G G GK +A A+ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 63 TRYAFRTF--------------------------NATIDSKKRLQEIAEEAKFSGGLVLL 96 + F A S R ++ + G L Sbjct: 184 GKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQ-------AEGGTLF 236 Query: 97 LDEIHRLDKTKQDFLLPLLENGTIIMIGATTENPF 131 LDEI + Q LL +L+ G +G T Sbjct: 237 LDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRS 271
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 30.0 bits (67), Expect = 0.021 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 22/145 (15%) Query: 242 GGQVMETVGIENMIGTLYT--EGPKLMAEVEAHTKSYDVDIIKAQLATSIEKKENIEVTL 299 G M+ G+E +GTL E P + A + + + +DI+K K++ + T Sbjct: 205 NGSAMQIRGVEKALGTLKITHENPNVEANYDENAAALSIDIVK--------KQKGGKGTA 256 Query: 300 ANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGVTYCPHCDGPLFEGKDVAVIGGGNSG 359 A G + + + + RN+ +D+F K DG + K + GN Sbjct: 257 AQGIYINSTSGTTGKLLRIRNLG---DDKFYVKH-------DGGFYAKKTSQI--DGNLK 304 Query: 360 LEAALDLAGLAKHVYVLEFLPELKA 384 L+ A YV + +LKA Sbjct: 305 LKNPTADDHAATKAYVDSEVKKLKA 329
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 47.4 bits (113), Expect = 7e-08 Identities = 22/53 (41%), Positives = 32/53 (60%), Gaps = 6/53 (11%) Query: 46 IAIKDGLIVALG-SGEPDAE-----LVGPQTIMRSYKGKIATPGIIDCHTHLV 92 I +KDG I A+G +G PD + +VGP T + + +GKI T G +D H H + Sbjct: 88 IGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFI 140
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.8 bits (69), Expect = 0.019 Identities = 20/118 (16%), Positives = 35/118 (29%), Gaps = 17/118 (14%) Query: 438 NAYYDPQQNQIVFPAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDT---------N 488 + + A + S+ N+ +G + + N Sbjct: 594 YLNLENYTYYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFN 653 Query: 489 GASFDEHGSLNDWWTQEDYAAFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGG 546 G +E G N FK ++++ G G +NG LTV + L G Sbjct: 654 GYFGEEEGKNNGNLN----VTFKGKSEQNRFLLTG----GTNLNGDLTVEKGTLFLSG 703
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.007 Identities = 6/18 (33%), Positives = 12/18 (66%) Query: 610 LVKQGDQVKAGQTLIQFD 627 +VK+G+ V+ G L++ Sbjct: 111 IVKEGESVRKGDVLLKLT 128
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 90.3 bits (224), Expect = 3e-22 Identities = 65/341 (19%), Positives = 135/341 (39%), Gaps = 22/341 (6%) Query: 37 KKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRS--QLLQIDYVLKMEESLLKGQGLAD 94 +LS+ + LA L++ E + + + + + + +++G LAD Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 95 MLSGLG--FSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRRKTVEVITYPLILLLF 152 + F ++ + G+++ L + Y Q ++R + + + YP +L + Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 153 LFVMMLGLRRYLVPQLETQNQ---------------ITYFLNHFPAFFIGFCSGLILLFG 197 ++ L +VP++ Q ++ + F + + + F Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 198 MVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDIMAIE 257 + LR + + R+ + RL P +G++ + T+ YAR L + L+ + I Sbjct: 243 V-MLR-QEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 258 KSSL-MKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELEIYAQE 316 S+ + ++ EG + H + F + MI GE +L + LE A Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 317 SWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQ 357 +F SQ+ L +P + + +A ++ I AIL PI Q Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQ 401 Score = 34.8 bits (80), Expect = 4e-04 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 6/129 (4%) Query: 235 REWGTLIGQGLDLMTILDIMAIE-KSSLMKELAEDIRMSLLEGQAFHIKVATYP-FFKKE 292 R+ TL+ + L LD +A + + + +L +R ++EG + + +P F++ Sbjct: 75 RQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADAMKCFPGSFERL 134 Query: 293 LSLMIEYGEIKSKLGAELEIYA--QESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAA 350 M+ GE L A L A E +Q S++ Q +I P + VVA+ +V I + Sbjct: 135 YCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQA--MIYPCVLTVVAIAVVSILLS 192 Query: 351 ILLPIYQNM 359 +++P Sbjct: 193 VVVPKVVEQ 201
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 52.6 bits (126), Expect = 4e-12 Identities = 28/94 (29%), Positives = 50/94 (53%), Gaps = 4/94 (4%) Query: 9 RHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELS 68 K +GFTLLE+++VI++I VL L VPNL K++ + + + +EN ++Y+L Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLD 62 Query: 69 QGSKPSLSQ-LKA--DGSITEKQEKAY-QDYYDK 98 P+ +Q L++ + Y ++ Y K Sbjct: 63 NHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIK 96
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 26.5 bits (58), Expect = 0.037 Identities = 17/71 (23%), Positives = 25/71 (35%), Gaps = 9/71 (12%) Query: 37 LLKRSHYLARHDQDNWLLFSHQL--REELSGARFYKVADNK-LYVEKGKKVLAFGQFKSH 93 K S ++ D D ++ R ++ +Y VA N YV KV G + Sbjct: 217 TFKYSGWVESSDNDEHYDPGKRITYRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRV 276 Query: 94 DFRKSASNGKG 104 N KG Sbjct: 277 T------NKKG 281
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 500 bits (1290), Expect = e-180 Identities = 209/401 (52%), Positives = 281/401 (70%), Gaps = 7/401 (1%) Query: 3 KTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTE 62 K + IN GSSSLK+QL + + VLA+G+ ERIG+ DS+ T +G+K + D+ DH + Sbjct: 2 KILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKD 61 Query: 63 AVKILLNDLI--HFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEHIEELSVLAPL 120 A+K++L+ L+ +G+I EI VGHRVV GGE F SV++ D VL+ I + LAPL Sbjct: 62 AIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121 Query: 121 HNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGT 180 HNP GI+A I+PD+ V VFDT+FH +M + YLYPIP +YYT YK+RKYG HGT Sbjct: 122 HNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGT 181 Query: 181 SHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRS 240 SHKYV+Q AA++L +P+E LK+IT H+GNG SI A +GKS+DTSMGFTPL G MGTRS Sbjct: 182 SHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRS 241 Query: 241 GDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDI-EAGLQEDNPDAV 299 G IDP+II YL+E+ E A +VVN+LNKKSG+ G+SGISSD RD+ +A + + A Sbjct: 242 GSIDPSIISYLMEK--ENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQ 299 Query: 300 LAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKN 359 LA N+F R+KK IG Y A + G D +VFTAG+GEN P +R+ ++ GL + G +D EKN Sbjct: 300 LALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKN 359 Query: 360 -VFGYRGDISTPESKVKVLVISTDEELCIARDVERL-KNTK 398 V G IST +SKV V+V+ T+EE IA+D E++ ++ K Sbjct: 360 KVRGEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIVESLK 400
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.007 Identities = 11/63 (17%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 50 ERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFVPISFKYKVSALDF 109 GD L D+ + + +L I++ P+ ++ ++ + F+ + A D+ Sbjct: 44 AAGDGDLVVTDVVMPD--ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDY 101 Query: 110 IDK 112 + K Sbjct: 102 LPK 104
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 162 bits (412), Expect = 1e-48 Identities = 66/237 (27%), Positives = 116/237 (48%), Gaps = 20/237 (8%) Query: 31 VTAQSSSGWDQLVYLFARAIQWL-----SFDGSIGVGIILFTLTIRLMLMPLFNMQIKSS 85 + GW + ++ + L SF G+ G II+ T +R ++ PL Q S Sbjct: 324 LDLTVDYGWLWFI---SQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSM 380 Query: 86 QKMQDIQPELRELQKKYAGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIAL 145 KM+ +QP+++ ++++ + ++++E ALYK VNP PLLIQMP+ +AL Sbjct: 381 AKMRMLQPKIQAMRERLGDD----KQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLAL 436 Query: 146 FQALTRVSFLKTGTF-LWV-ELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVM 203 + L L+ F LW+ +L+ D Y+LP+L V F ++ + M + Sbjct: 437 YYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMS--PTTVTDPMQQKI 494 Query: 204 IYVMPLMIFFMGFNLASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKER 260 + MP++ SG+VLY+ VSN ++Q L+ E++ L + EK++ Sbjct: 495 MTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYR----GLEKRGLHSREKKK 547
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.047 Identities = 29/156 (18%), Positives = 49/156 (31%), Gaps = 20/156 (12%) Query: 57 KTVYKADKKATRGVPEN----------------INQKHAPAVNSADVEPEEIKATQKLEA 100 KTV K ++ AT +N N+ + + + E K T +E Sbjct: 1049 KTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEK 1108 Query: 101 EDTKVVPLMPEDSPAQTPSNLAETVTETKAQQPSIPVEESEVPQDAGNDGFSKDIEKAAQ 160 E+ V + S ++ +++ QP P + S+ A Sbjct: 1109 EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT 1168 Query: 161 EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPE 196 E T ++E V S N +E PE Sbjct: 1169 EQPAKETS----SNVEQPVTESTTVNTGNSVVENPE 1200
>adhesinb#Adhesin B signature. Length = 310 Score = 30.6 bits (69), Expect = 0.011 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 2/34 (5%) Query: 3 MKKLASLAMLGASVLGLAACGGKSQKEAGASKSD 36 MKK L +L + +GLAAC SQK + + S Sbjct: 1 MKKCRFLVLLLLAFVGLAACS--SQKSSTETGSS 32
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 279 bits (714), Expect = 4e-97 Identities = 115/257 (44%), Positives = 161/257 (62%), Gaps = 19/257 (7%) Query: 11 MVFFVLVTFLGLTISQEVFA--QQDPDPSQLHRSS-LVKNLQNIYFLYEGDPVTHENVKS 67 ++ F L+ + + V A Q DP P LH+SS + N+ +LY+ V+ VKS Sbjct: 11 ILIFALIL---VISTPNVLAESQPDPMPDDLHKSSEFTGTMGNMKYLYDDHYVSATKVKS 67 Query: 68 VDQLLSHDLIYNVSGP---NYDKLKTELKNQEMATLFKDKNVDIYGVEYYHLCYLCE--- 121 VD+ L+HDLIYN+S NYDK+KTEL N+++A +KD+ VD+YG YY CY Sbjct: 68 VDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKDEVVDVYGSNYYVNCYFSSKDN 127 Query: 122 ---NAERSACIYGGVTNHEGNHLEIP--KKIVVKVSIDGIQSLSFDIETNKKMVTAQELD 176 C+YGG+T HEGNH + + ++V+V + ++SF+++T+KK VTAQELD Sbjct: 128 VGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTAQELD 187 Query: 177 YKVRKYLTDNKQLYTNGPSKYETGYIKFIPKNKESFWFDFFPEP--EFTQSKYLMIYKDN 234 K R +L + K LY S YETGYIKFI N +FW+D P P +F QSKYLM+Y DN Sbjct: 188 IKARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDN 247 Query: 235 ETLDSNTSQIEVYLTTK 251 +T+DS + +IEV+LTTK Sbjct: 248 KTVDSKSVKIEVHLTTK 264
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 30.9 bits (70), Expect = 0.009 Identities = 15/55 (27%), Positives = 24/55 (43%), Gaps = 9/55 (16%) Query: 304 IVNDTII--IDDFA-----HHPTEIVATIDAARQKYPSKEIVAIFQPHTFTRTIA 351 ++ D ++ I D H+P I I A Q P +VA+F F +T+ Sbjct: 103 LITDDVLKAITDCIELAPLHNPANIEG-IKACTQIMPDVPMVAVFDT-AFHQTMP 155
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.8 bits (72), Expect = 7e-04 Identities = 26/120 (21%), Positives = 45/120 (37%), Gaps = 29/120 (24%) Query: 46 VALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVGTAL 105 + ++ +G I+ + N GY I +++AK ++++GVGTAL Sbjct: 69 LYYLENNCIGRIK----------------IRSN--WNGYALIEDIAVAKDYRKKGVGTAL 110 Query: 106 LAALKDLVVAQQRTGLILTCHDYLIS---YYEMNGFINQGISESQHGGT--------LWY 154 L + GL+L D IS +Y + FI + + WY Sbjct: 111 LHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSNFPTANEIAIFWY 170
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 136 bits (344), Expect = 1e-38 Identities = 70/231 (30%), Positives = 116/231 (50%), Gaps = 22/231 (9%) Query: 38 WEFLGKPMSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQS-EKMTFL 96 F+ +P+ + + + G +G +III+T IVR ++ PL KA Y S KM L Sbjct: 333 LWFISQPLFKLLKWIHSFVG-NWGFSIIIITFIVRGIMYPLT-----KAQYTSMAKMRML 386 Query: 97 KPVFEPINKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFA 156 +P + + +R+ ++K E+MA +A +NPLGG C PLLIQMP F A+Y+ Sbjct: 387 QPKIQAMRERLG-----DDKQRISQEMMALYKAEKVNPLGG--CFPLLIQMPIFLALYYM 439 Query: 157 AQYTKGVSTSTFMG--IDLGSR--SLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMY 212 + + + F DL ++ +L ++ FF +S V++ + +M Sbjct: 440 LMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPM---QQKIMT 496 Query: 213 TMPIMMIFMSFSLPAGVGLYWLVGGFFSIIQQ-LITTYLLKPRLHKQIKEE 262 MP++ P+G+ LY++V +IIQQ LI L K LH + K++ Sbjct: 497 FMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKK 547
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 97.1 bits (241), Expect = 7e-25 Identities = 46/123 (37%), Positives = 65/123 (52%), Gaps = 8/123 (6%) Query: 23 SLTAAQAILESGWGKHA-------PHNALFGIKADASWTGKSFNTKTQEEYQAGVITDIV 75 L AQA LESGWG+ P LFG+KA +W G T E Y+ G + Sbjct: 172 HLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE-YENGEAKKVK 230 Query: 76 DRFRAYDSWDESIADHGQFLVDNPRYQSVIGEADYKKACHAIKDAGYATASGYAELLIQI 135 +FR Y S+ E+++D+ L NPRY +V A ++ A++DAGYAT YA L + Sbjct: 231 AKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNM 290 Query: 136 IEE 138 I++ Sbjct: 291 IQQ 293
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 171 bits (435), Expect = 4e-55 Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 28/254 (11%) Query: 6 IIKIVFIITVILISTISPIIKSDSKKDISNVKSDLLYAYTITPYDYKDCRVNFSTT---- 61 +I I +I VI + + D D + S+ Y Y D V+ + Sbjct: 10 VILIFALILVISTPNVLAESQPDPMPDDLHKSSEFTGTMGNMKYLYDDHYVSATKVKSVD 69 Query: 62 ----HTL--NIDTQKYRGKDYYISSEMSYEASQKFKRDDHVDVFGLFYILNSHTGEY--- 112 H L NI +K + D + ++ + ++K+K D+ VDV+G Y +N + Sbjct: 70 KFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYK-DEVVDVYGSNYYVNCYFSSKDNV 128 Query: 113 ---------IYGGITPAQNNKVNHKLLGNLFIS-GESQQN-LNNKIILEKDIVTFQEIDF 161 +YGGIT + N ++ L N+ + E+++N ++ ++ +K VT QE+D Sbjct: 129 GKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTAQELDI 188 Query: 162 KIRKYLMDNYKIYD-ATSPYVSGRIEIGTKDGKHEQIDLFDSPNEG-TRSDIFAKYKDNR 219 K R +L++ +Y+ +SPY +G I+ +G D+ +P + +S Y DN+ Sbjct: 189 KARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNK 248 Query: 220 IINMKNFSHFDIYL 233 ++ K+ +++L Sbjct: 249 TVDSKS-VKIEVHL 261
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 47.4 bits (113), Expect = 5e-08 Identities = 42/191 (21%), Positives = 79/191 (41%), Gaps = 16/191 (8%) Query: 170 RKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVASMRAQELQYTNI 229 R++ + AG + +I P+A A G+ V+D+GGG T VA + + Y++ Sbjct: 127 RESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSS 186 Query: 230 YAEGGEYITKDISKVLKTSLAI------AEALKFNFGQAEISEASITETVK-VDVV-GSE 281 GG+ + I ++ + AE +K G A + V+ ++ G Sbjct: 187 VRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVP 246 Query: 282 EPVEVTERYLSEIISARIRHILDRVKQDLER------GRLLDLPGGIVLIGGGAIMPGVV 335 + + E + + I+ V LE+ + + G+VL GGGA++ + Sbjct: 247 RGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISE--RGMVLTGGGALLRNLD 304 Query: 336 EIAQEIFGVTV 346 + E G+ V Sbjct: 305 RLLMEETGIPV 315
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 30.7 bits (69), Expect = 0.010 Identities = 19/99 (19%), Positives = 31/99 (31%), Gaps = 10/99 (10%) Query: 154 FEQEDQLSKVKHLGAVTKVFKDANQMPESTQLE-AVKEYFSRDLKTLLFIGGSAGAHVFN 212 FE ++K + + N + S+ E A S K + G Sbjct: 83 FEALKAINKQTGI--------EINNVEPSSNFESAYNSALSAGHKIWVLNGFKHQQS-IK 133 Query: 213 QFISDHPELKQRYNIINITGDPHLNELSSHLYRVDYVTD 251 Q+I H E +R I I D + Y + + Sbjct: 134 QYIDAHREELERNQIKIIGIDFDIETEYKWFYSLQFNIK 172
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 186 bits (474), Expect = 3e-53 Identities = 102/477 (21%), Positives = 187/477 (39%), Gaps = 97/477 (20%) Query: 8 IRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQE--RAMDSNDLEKERGITILAKNTA 65 I N+ ++AHVD GKTTL + LL S + E + + D+ LE++RGITI T+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 66 VAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQNLI 125 + + ++NI+DTPGH DF EV R + ++DG +L++ A +G QTR + + + Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 126 PIVVVNKIDKPSARP-------------------------------------AEVVDEVL 148 I +NKID+ + V E Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182 Query: 149 ELFIELGADDEQLE-----------------FPVVYASAINGTSSLSDDPADQEHTMAPI 191 + +E + LE FPV + SA N + + Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIG------------IDNL 230 Query: 192 FDTIIDHIPAPVDNSDEPLQFQVSLLDYNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTT 251 + I + + L +V ++Y++ R+ R++ G + + D V +S Sbjct: 231 IEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRIS----EK 286 Query: 252 KNFRVTKLFGFFGLERREIQEAKAGDLIAVSGMEDIFVGETITPTDCVEALPILRIDEPT 311 + ++T+++ E +I +A +G+++ + E + + + T + + P Sbjct: 287 EKIKITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPL 345 Query: 312 LQMTFLVNNSPFAGREGKWITSRKVEER--LLAELQT----DVSLRVDPTDSPDKWTISG 365 LQ T + K ++R LL L D LR + + +S Sbjct: 346 LQTT---------------VEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSF 390 Query: 366 RGELHLSILIETMRRE-GYELQVSRPEVIIKEIDGVKCEPFERVQIDTPEEYQGAII 421 G++ + + ++ + E+++ P VI E K E + I+ P A I Sbjct: 391 LGKVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAE--YTIHIEVPPNPFWASI 445 Score = 42.5 bits (100), Expect = 4e-06 Identities = 18/79 (22%), Positives = 31/79 (39%), Gaps = 1/79 (1%) Query: 403 EPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPARGLIGYSTEFLS 462 EP+ +I P+EY + +++D Q + N + L IPAR + Y ++ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRSDLTF 595 Query: 463 MTRGYGIMNHTFDQYLPVV 481 T G + Y Sbjct: 596 FTNGRSVCLTELKGYHVTT 614
>PF03309#Bvg accessory factor Length = 271 Score = 31.3 bits (71), Expect = 0.004 Identities = 29/126 (23%), Positives = 43/126 (34%), Gaps = 14/126 (11%) Query: 5 LLGIDLGGTTIKFGILTAAGEVQE---KWAIETNILEGGKHIVPDIVASIKHRLDLYGLS 61 LL ID+ T G+++ +G+ + +W I T + D +A L G Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTE-----PEVTADELALTIDG--LIGDD 54 Query: 62 SADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVEKELGIPFAIDNDANVAALG 121 + G S V + V W V GIP +DN V A Sbjct: 55 AERLTGASGLS--TVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVGA-- 110 Query: 122 ERWVGA 127 +R V Sbjct: 111 DRIVNC 116
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 578 bits (1492), Expect = 0.0 Identities = 191/410 (46%), Positives = 276/410 (67%), Gaps = 9/410 (2%) Query: 5 TPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDE 64 PI+++SEIG+LKKVLLHRPG+E+ENL P ++ LFDDIP+LE A++EH+ FA L++ Sbjct: 6 NPINIFSEIGRLKKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQEHEVFASILKNN 65 Query: 65 GIEVLYLETLAAESLVTP-EIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEK 123 +E+ Y+E L +E LV+ + FI +++ EA I+ T +++ ++ +I K Sbjct: 66 LVEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINLLKDYFSSL-TIDNMISK 124 Query: 124 TMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSE 183 ++GV EL +S L DLV F IDPMPN+ FTRDPFA+IG GV++N MF++ Sbjct: 125 MISGVVTEELKNYTSS---LDDLVNGANLFIIDPMPNVLFTRDPFASIGNGVTINKMFTK 181 Query: 184 TRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAA 243 R RET++ +YIF +HP+Y VP+ +R E +EGGDELVL+K +L +GIS+RT+A Sbjct: 182 VRQRETIFAEYIFKYHPVYKE-NVPIWLNRWEEASLEGGDELVLNKGLLVIGISERTEAK 240 Query: 244 SIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSV 303 S+EKL +++FK F +LAF+ NR +MHLDTVFT +DY FT + +Y + Sbjct: 241 SVEKLAISLFKNKTSFDTILAFQIPKNRSYMHLDTVFTQIDYSVFTSFTSDDMYFSIYVL 300 Query: 304 TYDNE--ELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAP 361 TY+ ++HI +EK + ++L+ LG K+D+I+C G +L+ REQWNDG+N L IAP Sbjct: 301 TYNPSSSKIHIKKEKARIKDVLSFYLG-RKIDIIKCAGGDLIHGAREQWNDGANVLAIAP 359 Query: 362 GVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI 411 G ++ Y+RN +TN + E G+K+ +I SEL RGRGGPRCMSMP REDI Sbjct: 360 GEIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGPRCMSMPLIREDI 409
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 123 bits (311), Expect = 4e-39 Identities = 60/146 (41%), Positives = 92/146 (63%), Gaps = 2/146 (1%) Query: 1 MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDT 60 MNK + RH IR +I+ I TQ EL + L+K+G +TQAT+SRD+KEL+LVKV + N + Sbjct: 1 MNKGQ-RHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGS 59 Query: 61 HYEALAISQTRWEH-RLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIV 119 + +L Q +L+ + DA V + H I+LKT+PG AQ+ G+++D + EI+ Sbjct: 60 YKYSLPADQRFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEEIM 119 Query: 120 ATVCGDDTCLIVCEDNEQAKACYETL 145 T+CGDDT LI+C ++ K + + Sbjct: 120 GTICGDDTILIICRTHDDTKVVQKKI 145
>PF06580#Sensor histidine kinase Length = 349 Score = 180 bits (459), Expect = 5e-54 Identities = 58/203 (28%), Positives = 102/203 (50%), Gaps = 10/203 (4%) Query: 362 EKEIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGN- 420 + +L AL +QINPHF++N L+ I + D + E+ SL++ R +L N Sbjct: 155 ASMAQEAQLMALKAQINPHFMFNALNNIRALIL-EDPTKAREMLTSLSELMRYSLRYSNA 213 Query: 421 DYIRLADELDHVSQYLFIQKQRYGDKLTYDVQGLDAYADFIIPKLILQPLVENAIYHGIK 480 + LADEL V YL + ++ D+L ++ Q A D +P +++Q LVEN I HGI Sbjct: 214 RQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA 273 Query: 481 EVDRKGMIKVTVSETAQHLILTVWDNGKGIEASALTNSQSLLTRGGVGLKNVDQRLKLQY 540 ++ + G I + ++ + L V + G + ++ G GL+NV +RL++ Y Sbjct: 274 QLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKEST-------GTGLQNVRERLQMLY 326 Query: 541 GEAYQMTIHSQSDHFTEIQLSLP 563 G Q+ + + + + +P Sbjct: 327 GTEAQIKLSEKQGKVNAM-VLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 95.7 bits (238), Expect = 9e-25 Identities = 43/165 (26%), Positives = 75/165 (45%), Gaps = 12/165 (7%) Query: 3 SLLIVEDEYLIRQGVRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLN 62 ++L+ +D+ IR + + + + V N W D+V+TD+ MP N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY---DVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLRKK 122 L IK+ P ++ ++ + F A+ A + GA DYL KPF D+ +++G + + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF---DLTELIGIIGRA 118 Query: 123 LELSKKTETIQELVEQPQKEVSAIAMAIHE------RLADSDLTL 161 L K+ + E Q + + A+ E RL +DLTL Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 28.2 bits (63), Expect = 0.046 Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Query: 255 LASVATSIVGVVSFLGL---IVPHMSRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLA 311 + S A + +GL H S+L++ Q +PFS L V + L Sbjct: 29 VVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQSYLPFSQALSYVVDNVLLEFF-YLC 87 Query: 312 YPLEISPAIIMSIVGG 327 +PL ++ A +M+I Sbjct: 88 FPL-LTVAALMAIASH 102
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 71.1 bits (174), Expect = 1e-15 Identities = 55/265 (20%), Positives = 104/265 (39%), Gaps = 24/265 (9%) Query: 304 VACVNQHPKTAKETEQQRIVATSVAVVDICDRLNLDLVGVCDSKLYTL----PKRYDAVK 359 + A + RIVA V++ L + GV D+ Y L P D+V Sbjct: 20 PLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVI 79 Query: 360 RVGLPMNPDIELIASLKPTWILSPNSLQEDLEPKYQKLDTEYGFLNLRSVEG------MY 413 VGL P++EL+ +KP++++ P + L +G Sbjct: 80 DVGLRTEPNLELLTEMKPSFMV----WSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMAR 135 Query: 414 QSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAKRKGK-KKPKVLILMGLPGSYLVATNQS 472 +S+ ++ +L Q A+ QY+D+ R+ + + + +P +L + P LV S Sbjct: 136 KSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNS 195 Query: 473 YVGNLLDLAGGENVYQ--SDEKEFLSVNPEDMLA-KEPDLILRTAHAIPDKVKVMFDKEF 529 +LD G N +Q ++ +V+ + + A K+ D++ D +M Sbjct: 196 LFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALM----- 250 Query: 530 AENDIWKHFTAVKEGKVYDLDNTLF 554 +W+ V+ G+ + F Sbjct: 251 -ATPLWQAMPFVRAGRFQRVPAVWF 274
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 33.8 bits (77), Expect = 0.001 Identities = 18/89 (20%), Positives = 29/89 (32%) Query: 76 SNSLVNADDKKRSDSSQSVVGSSDNKAEAENQVDDKSTDHSKPTDHSKPTDHSKPTDQPK 135 S ++V D + + Q + + + + KP KP K Sbjct: 46 SVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKK 105 Query: 136 PTDQPKPSPSKVDTAPASSLSRQLPEVRT 164 +QPK V++ PAS P T Sbjct: 106 VQEQPKRDVKPVESRPASPFENTAPARLT 134
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 344 bits (883), Expect = e-119 Identities = 122/367 (33%), Positives = 195/367 (53%), Gaps = 21/367 (5%) Query: 7 RPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQVSKALLPQVDGYCVSN 66 RP A ++LQA+K+N++ V++ + ++VVKA+AYGHG ++ A+ DG+ + N Sbjct: 3 RPIQASLDLQALKQNLSIVRQAAT-HARVWSVVKANAYGHGIERIWSAI-GATDGFALLN 60 Query: 67 LDEALQLRQAGIDKEILIL-GVLLPNELKLAITRQVTVTVASLEWLAMAKQEWPDLKG-L 124 L+EA+ LR+ G IL+L G +L++ ++T V S L + LK L Sbjct: 61 LEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNA--RLKAPL 118 Query: 125 KVHIKIDSGMGRIGLRSVTEVDNLIAGLKSMGAD-VEGIFTHFATADEADDTKFNQQLQF 183 +++K++SGM R+G + V + L++M + +HFA A+ D + Sbjct: 119 DIYLKVNSGMNRLGFQP-DRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGIS--GAMAR 175 Query: 184 FKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVRLGIVSYGLNPSGS-DLSLPFPLQEA 242 ++ GL SNSA ++WH + F+ VR GI+ YG +PSG L+ Sbjct: 176 IEQAAEGL---ECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPV 232 Query: 243 LSLESSLVHVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNM-QGFSVLVDGQF 301 ++L S ++ V+ + AG+ VGYG YTA+ + +G V GYADG+ R+ G VLVDG Sbjct: 233 MTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVR 292 Query: 302 CEIIGRVSMDQLTIRLSKA--YPLGTKVTLIGSNQQKNISTTDIANYRNTINYEVLCLLS 359 +G VSMD L + L+ +GT V L G K I D+A T+ YE++C L+ Sbjct: 293 TMTVGTVSMDMLAVDLTPCPQAGIGTPVELWG----KEIKIDDVAAAAGTVGYELMCALA 348 Query: 360 DRIPRIY 366 R+P + Sbjct: 349 LRVPVVT 355
>SECA#SecA protein signature. Length = 901 Score = 1052 bits (2723), Expect = 0.0 Identities = 394/903 (43%), Positives = 560/903 (62%), Gaps = 73/903 (8%) Query: 1 MANILRKVIENDKG-ELRKLEKIAKKVESYADQMASLSDRDLQGKTLEFKERYQKGETLE 59 + +L KV + LR++ K+ + + +M LSD +L+GKT EF+ R +KGE LE Sbjct: 2 LIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLE 61 Query: 60 QLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNAI 119 L+PEAFAVVREA+KRV G+ + VQ++GG+VL+ + EMRTGEGKTLTAT+P YLNA+ Sbjct: 62 NLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL 121 Query: 120 AGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKSPAEKREAYNCDITYSTNSE 179 G+GVHV+TVN+YL+ RDA ++ +LGL+VGINL KREAY DITY TN+E Sbjct: 122 TGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNE 181 Query: 180 VGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRAD 239 GFDYLRDNM E+ VQR L++ALVDEVDS+LIDEARTPLI+SG + ++Y R + Sbjct: 182 YGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSS-EMYKRVN 240 Query: 240 MFVKTLT------------SVDYVIDVPTKTIGLSDSGIDKAESYFNLS-------NLYD 280 + L + +D ++ + L++ G+ E +LY Sbjct: 241 KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS 300 Query: 281 IENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGLHQAIEA 340 N+ L H + ALRA+ + D+DY+V +DGE++IVD+ TGRTM+GRR+SDGLHQA+EA Sbjct: 301 PANIMLMHHVTAALRAHALFTRDVDYIV-KDGEVIIVDEHTGRTMQGRRWSDGLHQAVEA 359 Query: 341 KEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIA 400 KEGV+IQ E++T ASIT+QN FR+Y+KLAGMTGTA TE EF +Y + + +PTNRP+ Sbjct: 360 KEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMI 419 Query: 401 RIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKLVEAGIPHEVL 460 R D DL+Y T K +A++ED+K R AKGQP+LVGT+++E S+L+S +L +AGI H VL Sbjct: 420 RKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVL 479 Query: 461 NAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLG----------------------- 497 NAK H EA I+ AG AVTIATNMAGRGTDI LG Sbjct: 480 NAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKA 539 Query: 498 ------EGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFG 551 + V E GGL +IGTERHESRRIDNQLRGRSGRQGD G S+FYLS+ED LMR F Sbjct: 540 DWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFA 599 Query: 552 SDRIKAFLDRMKLDEEDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREI 611 SDR+ + ++ + + I+ + + + +AQ++VE N+D RKQ+L+YDDV +QR Sbjct: 600 SDRVSGMMRKLGM-KPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRA 658 Query: 612 IYANRRDVITANRDLGPEIKAMIKRTIDRAVDAHARSNR---KDAIDAIVTFARTSLVPE 668 IY+ R +++ + D+ I ++ + +DA+ I + + + Sbjct: 659 IYSQRNELLDVS-DVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLD 717 Query: 669 ESIS--AKELRGLKDDQIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWT 726 I+ + L ++ ++E++ +++ +Y ++ + E + F+K ++L +D+ W Sbjct: 718 LPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVG-AEMMRHFEKGVMLQTLDSLWK 776 Query: 727 EHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIH-EQE 785 EH+ A+D LR + LRGYAQ +P EY+ E F MF M+ +++++V T+ K Q+ +E Sbjct: 777 EHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEE 836 Query: 786 RERASQRATTAAPQNIQSQQSANTDD-------------LPKVERNEACPCGSGKKFKNC 832 E Q+ A + Q QQ ++ DD KV RN+ CPCGSGKK+K C Sbjct: 837 VEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQC 896 Query: 833 HGR 835 HGR Sbjct: 897 HGR 899
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.020 Identities = 9/16 (56%), Positives = 12/16 (75%) Query: 45 IIGASGSGKSLLAHAI 60 I G SG+GK L+A A+ Sbjct: 165 ITGESGTGKELVARAL 180
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 34.0 bits (77), Expect = 0.002 Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 2/87 (2%) Query: 226 IPKKDLSPSELAAAQAYWSQKQGRGARPSDY-RPTPAPGRRKAPIPDVTPNPRQGHQPD- 283 IP+ DL+P A A + P++ P PG R P PD NP D Sbjct: 310 IPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDG 369 Query: 284 NGGYHPAPPRPNDASQNKHQRDEFKGK 310 G P P D +H+++ +G+ Sbjct: 370 QPGTRPDSPAVPDRPNGRHRKERKEGE 396
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 250 bits (641), Expect = 1e-84 Identities = 84/323 (26%), Positives = 145/323 (44%), Gaps = 34/323 (10%) Query: 1 MKKGFFLMVMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVR-MI 59 MKK L+V+ +S +++ C Q + VV + + +TK ++GD D+ ++ Sbjct: 1 MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIV 60 Query: 60 QSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLE----AWARDLDPNLKKSKVDVFEASKP 115 G H +EP DV +ADL Y+ LE AW L N KK++ + A Sbjct: 61 PIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFA--- 117 Query: 116 LTLDRVKGLEDMEVTQGIDPATLY--------DPHTWTDPVLAGEEAVNIAKELGRLDPK 167 V+ G+D L DPH W + A NIAK+L DP Sbjct: 118 -------------VSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPN 164 Query: 168 HKDSYTKNAKAFKKEAEQLTEEYTQKFKKVR--SKTFVTQHTAFSYLAKRFGLKQLGISG 225 +K+ Y KN K + + ++L +E KF K+ K VT AF Y +K +G+ I Sbjct: 165 NKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWE 224 Query: 226 ISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT---LSPLEA 282 I+ E+E +P Q+K + + +++ V ++F E +V+ + +++ T + + Sbjct: 225 INTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAE 284 Query: 283 APSGNKTYLENLRANLEVLYQQL 305 +Y ++ NL+ + + L Sbjct: 285 QGKEGDSYYSMMKYNLDKIAEGL 307
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 107 bits (268), Expect = 3e-27 Identities = 50/226 (22%), Positives = 85/226 (37%), Gaps = 47/226 (20%) Query: 117 KAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVA 176 +G G VAV+D G D +H DL KA+ G + + Sbjct: 36 NQTRGRGVKVAVLDTGCDADHP----------------DL-KARIIGGRNFTDDDEGDPE 78 Query: 177 YYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLA 236 + DY+ HGTHV+G ++ + G PEA LL+++V G Sbjct: 79 IFKDYNG---------HGTHVAGTIAATENE-----NGVVGVAPEADLLIIKVLNKQGSG 124 Query: 237 DYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGND 296 Y Q I A+ +I+MS G E +A A + + ++ +AGN+ Sbjct: 125 QYD-WIIQGIYYAIEQKVDIISMSLGGPED-----VPELHEAVKKAVASQILVMCAAGNE 178 Query: 297 SSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETAT 342 +T +G P + ++V + + D+ +E + Sbjct: 179 GDGDDRT----------DELGYPGCYNEVISVGAINFDRHASEFSN 214 Score = 80.3 bits (198), Expect = 4e-18 Identities = 37/139 (26%), Positives = 57/139 (41%), Gaps = 22/139 (15%) Query: 457 NATPKVLPTASGTK---LSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSM 513 +V+ + S FS+ + D+ APG+DILS+V KYA SGTSM Sbjct: 192 GCYNEVISVGAINFDRHASEFSNSNN------EVDLVAPGEDILSTVPGGKYATFSGTSM 245 Query: 514 SAPLVAGIMGL-LQKQYEIQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGA 572 + P VAG + L Q D+T E L+ L + SP+ +G Sbjct: 246 ATPHVAGALALIKQLANASFERDLTEPE----LYAQLIKRTIPLGN-------SPKMEGN 294 Query: 573 GAVDAKKASA-ATMYVTDK 590 G + + ++ T + Sbjct: 295 GLLYLTAVEELSRIFDTQR 313
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 127 bits (321), Expect = 1e-34 Identities = 200/332 (60%), Positives = 232/332 (69%), Gaps = 8/332 (2%) Query: 68 HQLTVENKKLKIDKEQLTKENDDLKTEKDQLEQRSEKLATQKENLEKEVAEAKHKNETLN 127 L E L K L K + + + L +K LE AE + E Sbjct: 214 KTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAM 273 Query: 128 INNDDLTKKLNETRQELANKQQESKENEKTLNELLEKTVKDKIAREQKSKQDFGALKQEL 187 + + K+ E A + E K + + +++L + S++ L+ E Sbjct: 274 NFSTADSAKIKTLEAEKAALEAE-KADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEH 332 Query: 188 AKKEEQNKISEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLR 247 K EEQNKISEASR+ LRRDLDASREAKKQ+E AE K++E+ +IS+ASRQ LR Sbjct: 333 QKLEEQNKISEASRQSLRRDLDASREAKKQLE-------AEHQKLEEQNKISEASRQSLR 385 Query: 248 RDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALK 307 RDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALK Sbjct: 386 RDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALK 445 Query: 308 EQLAKQAEELAKLRAEKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQL 367 E+LAKQAEELAKLRA KASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQL Sbjct: 446 EKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQL 505 Query: 368 PSTGEAANPFFTAAAATVMVSAGMLALKRKEE 399 PSTGE ANPFFTAAA TVM +AG+ A+ +++E Sbjct: 506 PSTGETANPFFTAAALTVMATAGVAAVVKRKE 537 Score = 48.9 bits (116), Expect = 2e-08 Identities = 71/301 (23%), Positives = 119/301 (39%), Gaps = 2/301 (0%) Query: 1 MVRKDANRQYSLRKLKKSTASVAVALSALGVGLAVNQTEVSAAPLTRATADNKDELIKRA 60 M + + NR YSLRKLK TASVAVAL+ LG GL T +A TR+ D +++ +RA Sbjct: 1 MTKNNTNRHYSLRKLKTGTASVAVALTVLGAGLV-VNTNEVSAVATRSQTDTLEKVQERA 59 Query: 61 NGYEIQNHQLTVENKKLKIDKEQLTKENDDLKTEKDQLEQRSEKLATQKENLEKEVAEAK 120 + +EI+N+ L ++N L + + L ND+L E +++ K ++ E + Sbjct: 60 DKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELE 119 Query: 121 HKNETLNINNDDLTKKLNETRQELANKQQESKENEKTLNELLEKTVKDKIAREQKSKQDF 180 + L + ++ + E K LEK ++ + Sbjct: 120 ARKADLEKALEGAMNFSTADSAKIKTLEAE-KAALAARKADLEKALEGAMNFSTADSAKI 178 Query: 181 GALKQELAKKEEQNKISEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISD 240 L+ E A E + E + +G A K +E + A L A +++ + + Sbjct: 179 KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAM 238 Query: 241 ASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLE 300 + K +E E L + K E EKA L+A+ Sbjct: 239 NFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKA 298 Query: 301 A 301 Sbjct: 299 D 299 Score = 34.7 bits (79), Expect = 6e-04 Identities = 56/272 (20%), Positives = 99/272 (36%), Gaps = 27/272 (9%) Query: 55 ELIKRANGYEIQNHQLTVENKKLKIDKEQLTKENDDLKTEKDQLEQRSEKLATQKENLEK 114 ++ + + + ++L+ K L K + + + L +K L Sbjct: 96 NAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAA 155 Query: 115 EVAEAKHKNETLNINNDDLTKKLNETRQELANKQQESKENEKTLNEL------------- 161 A+ + E + + K+ E A + E EK L Sbjct: 156 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKT 215 Query: 162 --------------LEKTVKDKIAREQKSKQDFGALKQELAKKEEQNKISEASRKGLRRD 207 LEK ++ + L+ E A E + E + +G Sbjct: 216 LEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNF 275 Query: 208 LDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRRDLDASREAKKQVEKALEEA 267 A K +E + A L AE ++ + Q+ +A+RQ LRRDLDASREAKKQ+E ++ Sbjct: 276 STADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKL 335 Query: 268 NSKLAALEKLNKELEESKKLTEKEKAELQAKL 299 + E + L + + K +L+A+ Sbjct: 336 EEQNKISEASRQSLRRDLDASREAKKQLEAEH 367
>PF05043#Transcriptional activator Length = 493 Score = 537 bits (1385), Expect = 0.0 Identities = 108/491 (21%), Positives = 217/491 (44%), Gaps = 16/491 (3%) Query: 13 RELKLISYLTENSNAIGVKDKELSKALNISMLTLQSCLTNMQFMKEVGGITYKDGYINIW 72 R+L+L+ L E+ EL++ LN + ++ L++++ I I Sbjct: 11 RQLELLELLFEHKRWFHRS--ELAELLNCTERAVKDDLSHVKSAFPDLIFHSSTNGIRII 68 Query: 73 YHQCCGLQEVYQKALRESPSLKLLELLFFRDFSSLEELAEELFVSLSTLKRLIKKTNTYL 132 ++ VY + S +LE +FF + E + +E ++S S+L R+I + N + Sbjct: 69 NTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRIISQINKVI 128 Query: 133 SHTFAISIVTSPVQVSGDERQIRLFYLKYFSEAYKISEWPFGDILNLKNCERLLSLLIKE 192 F + +PVQ+ G+ER IR F+ +YFSE Y EWPF + + + +LL L+ KE Sbjct: 129 KRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFEN-FSSEPLSQLLELVYKE 187 Query: 193 VDVKVHFTLFQHLKILSGVNLIRYYKGYSCSYNNKKTSHRFSQLIQHYSEIQDLSRLFYL 252 ++ + + LK+L NL R G+ + + + + I+ +++ F Sbjct: 188 TSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEGVAQSFES 247 Query: 253 KFGLHLDEYTIAEMFSNHLNDKLEIGCAFEIINQDPTSGGRQVTNWIHLL----DEMEIK 308 ++ + LDE + ++F ++ I E + V HLL D++ +K Sbjct: 248 EYNISLDEEVVCQLFVSYFQKMFFID---ESLFMKCVKKDSYVEKSYHLLSDFIDQISVK 304 Query: 309 LNLSITNKYEVAVTLHNASVLNEEDITANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEK 368 + I NK + LHN + L +++ ++LFD K + + +Q P+ + Sbjct: 305 YQIEIENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDVKKELSH 364 Query: 369 LMQADNAQVSKELINQLTYCFFITWENSFLKVNQKDEKVRLLVI----ERSYNSVGNFLK 424 ++ S ++N L+Y F ++ + + Q K+++LV+ + V L Sbjct: 365 YLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLS 424 Query: 425 KYIGEFFSITNFDELDCLTIDLVEIEKQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDR 484 Y F + + EL+ L + YD+I+++ ++ E + + + ++I Sbjct: 425 YYCSNNFELEVWTELELSKESLE--DSPYDIIISNFIIPPIENKRLIYSNNINTVSLIYL 482 Query: 485 LNEFLNVSFTD 495 LN + + + Sbjct: 483 LNAMMFIRLDE 493
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.0 bits (98), Expect = 7e-06 Identities = 29/151 (19%), Positives = 53/151 (35%), Gaps = 10/151 (6%) Query: 42 TADTATDAESETAKKDKKSKETASQHDTQKDHKPSHTHPTPPSNDTKQTDQASSEATDKP 101 T +T T ETA +K+ K TQ+ P T P + +T Q +E + Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEV--PKVTSQVSPKQEQSETVQPQAEP-ARE 1148 Query: 102 NKDKNDTKQPDSSDQSTSSPKDQSSQKESQNKDGRPTPSPDQQKDPTPD--KTPEK--SA 157 N + K+P S +T+ D + + + + + + PE A Sbjct: 1149 NDPTVNIKEPQSQTNTTA---DTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPA 1205 Query: 158 DKIPEKATEKTPEPNRDAPKPIQPPLAAAAP 188 P +E + +P + ++ P Sbjct: 1206 TTQPTVNSESSNKPKNRHRRSVRSVPHNVEP 1236
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 32.1 bits (73), Expect = 0.002 Identities = 14/62 (22%), Positives = 28/62 (45%), Gaps = 8/62 (12%) Query: 10 VINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKREFDQTSKQIKGKTVTEIRDILTKKI 69 V + LI+ ++ A+ + + KE +K+ +TEIRD+L ++ Sbjct: 82 VFDFLIVA------FAIFMAIKLINKLNRKKEEPAAAPAPTKEEV--LLTEIRDLLKEQN 133 Query: 70 NK 71 N+ Sbjct: 134 NR 135
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 1e-20 Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 1/128 (0%) Query: 3 KILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLE 62 ILV +DD I V+ + L YD + DL++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 VLKTIRKT-SDVPIIMLTALDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTP 121 +L I+K D+P+++++A + T + + DY+ KPF LI I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 DEKRQIGD 129 + D Sbjct: 125 RPSKLEDD 132
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 54.4 bits (131), Expect = 4e-10 Identities = 34/144 (23%), Positives = 55/144 (38%), Gaps = 10/144 (6%) Query: 60 DISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQPLFSYETSQRLTAQSSEF 119 +I T G++T + SK VK++ VK+G+ V+ G L +LTA +E Sbjct: 81 EIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLL------KLTALGAEA 134 Query: 120 DVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESLLEQIRSAEDSVSQAL 179 D + Q + A L+ Y I K PDE + + E +L Sbjct: 135 DTL----KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190 Query: 180 SDAKTADSDVKTAQIELDKANATA 203 + + + Q EL+ A Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRA 214 Score = 37.1 bits (86), Expect = 1e-04 Identities = 27/180 (15%), Positives = 60/180 (33%), Gaps = 16/180 (8%) Query: 120 DVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESL---LEQIRSAEDSVS 176 D + ++ +AK + Y VNE+ KS+ E L E + + Sbjct: 239 DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN 298 Query: 177 QALSDAKTADSDVKTAQIELDKANATAATEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKS 236 + L + ++ +EL K + + +++ + + L Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEE-------RQQASVIRAPVSVKVQQLKVHTEGGVV- 350 Query: 237 KKENETFMEII-DKSKMLVKGNISEFDRDKLKIDQKVEV-IDRKDNSK--KWTGKVTQVG 292 ET M I+ + + V + D + + Q + ++ ++ GKV + Sbjct: 351 -TTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN 409
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 27.2 bits (60), Expect = 0.006 Identities = 6/24 (25%), Positives = 9/24 (37%) Query: 22 YSKKVLADEPTSYQPPAAHSPCDD 45 + + A + T AA S D Sbjct: 27 KNPQPQAQQTTQTTTTAAGSAADQ 50