>SSPAMPROTEIN#Salmonella surface presentation of antigen gene type M signature. Length = 147 Score = 29.3 bits (65), Expect = 0.009 Identities = 14/30 (46%), Positives = 19/30 (63%) Query: 17 LSSIAGLPLLLKTGLYDNRGFTREEKFQLI 46 + IAGL LLL T +NR +REE + L+ Sbjct: 43 VEQIAGLKLLLDTLRAENRQLSREEIYALL 72
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 8e-23 Identities = 38/122 (31%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Query: 1 MAHETILVVDDEKEIRNLITIYLKNEGYKVLQAGDGEEGLRLLEENEVHLVVLDIMMPKV 60 M TILV DD+ IR ++ L GY V + R + + LVV D++MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGIHMCMKIREE-KEMPIIMLSAKTQDMDKILGLTTGADDYVTKPFNPLELIARIKSQLR 119 + + +I++ ++P++++SA+ M I GA DY+ KPF+ ELI I L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RY 121 Sbjct: 121 EP 122
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 27.1 bits (60), Expect = 0.028 Identities = 4/20 (20%), Positives = 9/20 (45%) Query: 19 GISRRVLYMRMYRYGWELQE 38 G++R L ++ G + Sbjct: 460 GLNRNTLRKKIRELGVSVYR 479
>SECA#SecA protein signature. Length = 901 Score = 900 bits (2327), Expect = 0.0 Identities = 354/829 (42%), Positives = 506/829 (61%), Gaps = 52/829 (6%) Query: 1 MLNSVKKLLGDSQKRKLKKYEQLVQEINNLEEKLSDLSDEELRHKTITFKDMLRDGKTVD 60 ++ + K+ G R L++ ++V IN +E ++ LSDEEL+ KT F+ L G+ ++ Sbjct: 2 LIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLE 61 Query: 61 DIKVEAFAVVREAAKRVLGLRHYDVQLIGGLVLLEGNIAEMPTGEGKTLVSSLPTYVRAL 120 ++ EAFAVVREA+KRV G+RH+DVQL+GG+VL E IAEM TGEGKTL ++LP Y+ AL Sbjct: 62 NLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL 121 Query: 121 EGKGVHVITVNDYLAKRDKELIGQVHEFLGLKVGLNIPQIDPSEKKLAYEADITYGIGTE 180 GKGVHV+TVNDYLA+RD E + EFLGL VG+N+P + K+ AY ADITYG E Sbjct: 122 TGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNE 181 Query: 181 FGFDYLRDNMAASKNEQVQRPYHFAIIDEIDSVLIDEAKTPLIIAGKKSSSSDLHYLCAK 240 +GFDYLRDNMA S E+VQR H+A++DE+DS+LIDEA+TPLII+G SS+++ K Sbjct: 182 YGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNK 241 Query: 241 VIKS-----------FQDTLHYTYDAESKSASFTEDGITKIEDLFDI-------DNLYDL 282 +I FQ H++ D +S+ + TE G+ IE+L ++LY Sbjct: 242 IIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSP 301 Query: 283 EHQTLYHYMIQALRAHVAFQCDVDYIVHDEKILLVDIFTGRVMDGRSLSDGLHQALEAKE 342 + L H++ ALRAH F DVDYIV D ++++VD TGR M GR SDGLHQA+EAKE Sbjct: 302 ANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKE 361 Query: 343 GLEITEENQTQASITIQNFFRMYPALSGMTGTAKTEEKEFNRVYNMEVMPIPTNRPIIRE 402 G++I ENQT ASIT QN+FR+Y L+GMTGTA TE EF+ +Y ++ + +PTNRP+IR+ Sbjct: 362 GVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRK 421 Query: 403 DKKDVVYVTADAKYKAVREDVLKHNKQGRPILIGTMSILQSETVARYLDEANITYQLLNA 462 D D+VY+T K +A+ ED+ + +G+P+L+GT+SI +SE V+ L +A I + +LNA Sbjct: 422 DLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNA 481 Query: 463 KSAEQEADLIATAGQKGQITIATNMAGRGTDILLG------------------------- 497 K EA ++A AG +TIATNMAGRGTDI+LG Sbjct: 482 KFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADW 541 Query: 498 ----EGVHELGGLHVIGTERHESRRVDNQLKGRAGRQGDPGSSQFFLSLEDEMLKRFAQE 553 + V E GGLH+IGTERHESRR+DNQL+GR+GRQGD GSS+F+LS+ED +++ FA + Sbjct: 542 QVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASD 601 Query: 554 EVEKLTKSLKTDETGLILTSKVHDFVNRTQLICEGSHFSMREYNLKLDDVINDQRNVIYK 613 V + + L I V + Q E +F +R+ L+ DDV NDQR IY Sbjct: 602 RVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYS 661 Query: 614 LRNNLLQEDTNMIEIIIPMIDHAVEAISKQYLVEGMLPEEWDFASLTASLNEI--LSVEN 671 RN LL + +++ E I + + +A Y+ L E WD L L L + Sbjct: 662 QRNELL-DVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPI 720 Query: 672 MPSLSANNVHSPEDLQS-VLKETLSLYKERVNELDSNTDLQQSLRYVALHFLDQNWVNHL 730 L E L+ +L +++ +Y+ + + + ++ + V L LD W HL Sbjct: 721 AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEM-MRHFEKGVMLQTLDSLWKEHL 779 Query: 731 DAMTHLKEGIGLRQYQQEDPTRLYQKEALDIFLYTYGNFEKEMCRYVAR 779 AM +L++GI LR Y Q+DP + Y++E+ +F + + E+ +++ Sbjct: 780 AAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSK 828
>INTIMIN#Intimin signature. Length = 939 Score = 51.6 bits (123), Expect = 1e-08 Identities = 66/340 (19%), Positives = 116/340 (34%), Gaps = 32/340 (9%) Query: 190 TVTKAEAAQFIAKTDKQFGTEAAKVESAKAVTTQKVEVKFSKAVEKLTKEDIKVT----- 244 T+T Q + + A SAKA T+ + + + + ++ V+ Sbjct: 545 TITVLSNGQVVDQV--GVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVS 602 Query: 245 -------NKANNDKVLVKEVTLSEDKKSATVELYSNLAAKQTYTVDVNKVGKTEVAVGSL 297 N AN + VTL DK V A+ T ++ N V + S+ Sbjct: 603 GTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAK--TAEMTSALNANAVIFVDQTKASI 660 Query: 298 EAKTIEMADQTVVADEPTALQFTVKDENGTEVVSPEGIEFVTPAAEKINAKGEITLAKGT 357 I+ T VA+ A+ +TVK G + VS + + F T K++ E T G Sbjct: 661 --TEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTT-TLGKLSNSTEKTDTNGY 717 Query: 358 ST-TVKAVYKKDGKVVAESKEVKVSAEGAAVASISNWTVAEQNKADFTSKDFKQNNKVYE 416 + T+ + V A +V V + V D + + + Sbjct: 718 AKVTLTSTTPGKSLVSARVSDVAVDVKAPEV------EFFTTLTIDDGNIEIVGTGVKGK 771 Query: 417 GDNAYVQVELKDQFNAVTTG---KVEYESLNTEVAVVDKATGKVTVLSAGKAPVKVTVKD 473 ++Q Q N +G K + S N +A VD ++G+VT+ G + V D Sbjct: 772 LPTVWLQ---YGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSD 828 Query: 474 SKGKELVSKTVEIEAFAQKAMKEIKLEKTNVALSTKDVTD 513 ++ T + + + N + Sbjct: 829 NQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLP 868
>INTIMIN#Intimin signature. Length = 939 Score = 34.7 bits (79), Expect = 0.002 Identities = 43/268 (16%), Positives = 77/268 (28%), Gaps = 34/268 (12%) Query: 335 VKFVANNLDGSPANIFEGGEATSTTGKLAVGIK----QGDYKVEVQVTKRGGLTVSNTGI 390 + AN+ S T L+ G V ++ K G + VS Sbjct: 580 YTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTA 639 Query: 391 ITVKNLDTPA-----------SAIKNVVFALDADNDGVVNYGSKLSGKDFALNSQNLVVG 439 L+ A + IK A+ + Y K+ D +++Q + Sbjct: 640 EMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEV--- 696 Query: 440 EKASLNKLVATIAGEDKVVDPGSISIKSSNHGIISVVNNYITAEAAGEATLTIKVGDVTK 499 + + + K+ +G V +T+ G++ ++ +V DV Sbjct: 697 ------------TFTTTLGKLSNSTEKTDTNGYAKVT---LTSTTPGKSLVSARVSDVAV 741 Query: 500 DVKFKVTTDSRKLVSVKANPDKLQVVQNKTLPVTFVTTDQYGDPFGANTAAIKEVLPKTG 559 DVK L N + + LP ++ Q Sbjct: 742 DVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPA 801 Query: 560 VVAEGGLDVVTTDSGSIGTKTIGVTGND 587 + + T GT TI V +D Sbjct: 802 IASVDASSGQVTLKEK-GTTTISVISSD 828
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 28.3 bits (63), Expect = 0.027 Identities = 5/35 (14%), Positives = 13/35 (37%) Query: 156 QGVSFLWSFLFETPFALMRGLAWLFIPAAIVMYLV 190 G+ + W+ + L + +V++L Sbjct: 852 AGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLC 886
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 2e-19 Identities = 34/125 (27%), Positives = 67/125 (53%), Gaps = 10/125 (8%) Query: 2 SILIVDDNPVNIFVIKKILKQAGYQDLVSLNSAQELFEYIHFGKDSSRHNEIDLILLDIM 61 +IL+ DD+ V+ + L +AGY D+ ++A L+ +I + DL++ D++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWI-------AAGDGDLVVTDVV 56 Query: 62 MPEIDGLEVCRRLQKEEKFKDIPIIFVTALEDANKLAEALDIGAMDYITKPINKVELLAR 121 MP+ + ++ R++K D+P++ ++A +A + GA DY+ KP + EL+ Sbjct: 57 MPDENAFDLLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114 Query: 122 MRVAL 126 + AL Sbjct: 115 IGRAL 119
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.3 bits (167), Expect = 6e-14 Identities = 25/107 (23%), Positives = 50/107 (46%), Gaps = 3/107 (2%) Query: 777 TIMIVDDDHRNIFALQNALKKQHANIITAQNGLECLEILKNNTNIDLILMDIMMPNMDGY 836 TI++ DDD L AL + ++ N + DL++ D++MP+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDG-DLVVTDVVMPDENAF 63 Query: 837 ETMEHIRMNLGLHEIPIIALTAKAMPNDKEKCLSAGASDYISKPLNL 883 + + I+ ++P++ ++A+ K GA DY+ KP +L Sbjct: 64 DLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDL 108
>PF07132#Harpin protein (HrpN) Length = 356 Score = 28.9 bits (64), Expect = 0.010 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Query: 51 SGEKVNSETAHKADIFSATGLVAGGVAGGLGGLLTGLGVLAVSGMGPIVAAGPIAAAIGG 110 G + ++ +DI + + + GGLGG L GLG G ++ G G Sbjct: 40 FGGQRSNIAEQLSDIMTTMMFMGSMMGGGLGGGLGGLGSSLGGLGGGLLGGG------LG 93 Query: 111 AGIGGGAGSLIGAFIGLGI 129 G+G GS +G+ +G G+ Sbjct: 94 GGLGSSLGSGLGSALGGGL 112
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 31.2 bits (70), Expect = 0.006 Identities = 21/108 (19%), Positives = 40/108 (37%), Gaps = 7/108 (6%) Query: 20 IKTATKGIASNGKPFLTVILQDPSGDIEAKLWDV-------SPEVEKQYVAETIVKVAGD 72 IK+ + I F +D G+I+A WD + +Y +V Sbjct: 779 IKSDSSVIVEEEINFDGTESKDEDGEIKAYEWDFGDGEKSNEAKATHKYNKTGEYEVKLT 838 Query: 73 ILNYKGRIQLRVKQIRVANENEVTDISDFVEKAPVKKEDMVEKITQYI 120 + + G I K+I+V + V I++ +K + + K + Sbjct: 839 VTDNNGGINTESKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLV 886
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.9 bits (168), Expect = 8e-17 Identities = 21/166 (12%), Positives = 62/166 (37%), Gaps = 3/166 (1%) Query: 1 MGRKISFNKERALNKAMHLFWEKGYDATYISDLIETMGISRSTLYDSFGDKDALFKLVLE 60 ++ ++ L+ A+ LF ++G +T + ++ + G++R +Y F DK LF + E Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 QYKNYGSQKRNLLFSDT--NTKESLKSFFYQHIEKCYSDDIPKGCIITNSSLLIGQIDPS 118 ++ + + + L+ +E +++ + + + + Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 119 IEEILINDFN-ELEKAFKQVIEEGKKKGEISQEDDTELVAYSLLSL 163 + + + E +Q ++ + + + T A + Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGY 170
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.3 bits (76), Expect = 0.002 Identities = 34/152 (22%), Positives = 63/152 (41%), Gaps = 3/152 (1%) Query: 36 IAKDLNIASDLSGLLTTLTQIGYGLGLFFIVPMADLFKSKKIIGILIGLTIISLIGTLIS 95 IA D N + + T + + +G ++D K+++ I + + + Sbjct: 40 IANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVG 99 Query: 96 TNGIVFLILTTVI-GIGACAAQMLVPLTM-RIVPIEEMGKYVGKVMSGLLIGIMIARPLS 153 + LI+ I G GA A LV + + R +P E GK G + S + +G + + Sbjct: 100 HSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIG 159 Query: 154 IGITEWFGWRMVFLFSLIILVAVLLLLIKFLP 185 I + W + L +I ++ V L+K L Sbjct: 160 GMIAHYIHWSYLLLIPMITIITV-PFLMKLLK 190
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 138 bits (348), Expect = 5e-38 Identities = 91/412 (22%), Positives = 191/412 (46%), Gaps = 13/412 (3%) Query: 17 NVKRLPILISMIIGAFFTILNETLLNVAFPQLMIELNVTPSTLQWLSTGYMLVVAVLIPA 76 N++ ILI + I +FF++LNE +LNV+ P + + N P++ W++T +ML ++ Sbjct: 9 NLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAV 68 Query: 77 SALLVQWFTTRQVFIGAMVVFTFGTLVSAIA-PGFSILLMGRLLQAAGTGLMMPVLMNTI 135 L +++ + +++ FG+++ + FS+L+M R +Q AG ++M + Sbjct: 69 YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVV 128 Query: 136 LLLYPPEKRGAAMGSIGLVIMFAPAIGPTLSGIILETLNWRWLFYIVLPFAIFSIVFAFI 195 P E RG A G IG ++ +GP + G+I ++W +L ++P V + Sbjct: 129 ARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLM 186 Query: 196 YLKNVSEPTKPKVDVLSILLSTIGFGGIVYGFSSSGEGWDSFQVYGIILIGLVALLFFVL 255 L K D+ I+L ++G + +S +++ +++ L FV Sbjct: 187 KLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSY--------SISFLIVSVLSFLIFVK 238 Query: 256 RQLKLKEPLLDLSAFKYPMFTLTTILLTIMMMTMFSTMTLLPFLFQGALGLTVYATG-LI 314 K+ +P +D K F + + I+ T+ ++++P++ + L+ G +I Sbjct: 239 HIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI 298 Query: 315 MLPGSLLNGLLSPVSGKLFDKFGPRALIIPGTLLLASVMWFFTQVTADTSKITFILLHVT 374 + PG++ + + G L D+ GP ++ G L SV + +T+ ++ V Sbjct: 299 IFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL-SVSFLTASFLLETTSWFMTIIIVF 357 Query: 375 MMVSISMIMMPAQTNGLNQLPKRFYPHGTAILNTLSQVAGAVGVAFFISVMT 426 ++ +S T + L ++ G ++LN S ++ G+A +++ Sbjct: 358 VLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 76.2 bits (187), Expect = 2e-19 Identities = 34/170 (20%), Positives = 67/170 (39%), Gaps = 3/170 (1%) Query: 6 QTSQNIVEASFKLMAEHGIEKMSLSMIAKEVGISKPAIYYHFSSKEALVDFLFEEIFS-- 63 +T Q+I++ + +L ++ G+ SL IAK G+++ AIY+HF K L ++E S Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 64 GYHFVSYFDKEQYTKENFVEKLIADGLHMLSEYEGQEGILRVINEFIVTAARNEKYQKRL 123 G + Y K + + +++ L E + ++ +I Q+ Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 124 FEIQEEFLNGFHELLKKGARLG-VVSQHATEENAHTLALVIDNMSNYMLM 172 + E + + LK + + T A + I + L Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 34.2 bits (78), Expect = 0.005 Identities = 16/62 (25%), Positives = 20/62 (32%) Query: 11 IQLIVVALIVTSVPLNGLAETAPPFTPSPNSEQSPETEKKEEKELPAPHPDQSKKDKAKA 70 I + +VA P P P P E PE K+ + P P K K Sbjct: 50 ISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 109 Query: 71 KA 72 K Sbjct: 110 KV 111
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 188 bits (478), Expect = 1e-59 Identities = 75/332 (22%), Positives = 141/332 (42%), Gaps = 26/332 (7%) Query: 1 MNILVTGGAGFIGSNFVHYMLQSYETYKIINFDALT--YSGNLNNVK-SIQDHPNYYFVK 57 M LVTG AGFIG + +L+ ++++ D L Y +L + + P + F K Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLE--AGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHK 58 Query: 58 GEIQNGELLEHVIKERDVQVIVNFAAESHVDRSIENPIPFYDTNVIGTVTLLELVKKYPH 117 ++ + E + + + + V S+ENP + D+N+ G + +LE + Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 118 IKLVQVSTDEVYGSLGKTGRFTEETPLA-PNSPYSSSKASADMIALAYYKTYQLPVIVTR 176 L+ S+ VYG L + F+ + + P S Y+++K + +++A Y Y LP R Sbjct: 119 QHLLYASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLR 177 Query: 177 CSNNYGPYQYPEKLIPLMVTNALEGKKLPLYGDGLNVRDWLHVTDHCSAIDVVLHKGRV- 235 YGP+ P+ + LEGK + +Y G RD+ ++ D AI + Sbjct: 178 FFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHA 237 Query: 236 -----------------GEVYNIGGNNEKTNVEVVEQIITLLGKTKKDIEYVTDRLGHDR 278 VYNIG ++ ++ ++ + LG + + + G Sbjct: 238 DTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI-EAKKNMLPLQPGDVL 296 Query: 279 RYAINAEKMKNEFDWEPKYTFEQGLQETVQWY 310 + + + + + P+ T + G++ V WY Sbjct: 297 ETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 43.6 bits (103), Expect = 4e-07 Identities = 36/200 (18%), Positives = 70/200 (35%), Gaps = 38/200 (19%) Query: 4 RVIITGANGQLGKQLQEEL--NPEE----------YDIYPFDKKL------------LDI 39 + ++TGA G +G + + L + YD+ +L +D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 40 TNISQVQQVVQEIRPHIIIHCAAYTKVDQAEKERDLAYV-INAIGARNVAVASQLVGAK- 97 + + + + V + E AY N G N+ + + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYS-LENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 98 LVYISTDYVFQGDRPEGYDEFHNPA-PINIYGASKYAGEQFVKELHNKYFIVRTSW---- 152 L+Y S+ V+ +R + + P+++Y A+K A E + Y + T Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFT 180 Query: 153 LYGKYGN------NFVKTMI 166 +YG +G F K M+ Sbjct: 181 VYGPWGRPDMALFKFTKAML 200
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 57.0 bits (137), Expect = 7e-12 Identities = 60/259 (23%), Positives = 105/259 (40%), Gaps = 19/259 (7%) Query: 4 LQGKTFVVMGVANQRSIAWGIARSLHNAGAKLI-FTYAGERLERNVRELADTLEGQESLV 62 ++GK + G A + I +AR+L + GA + Y E+LE+ V L E + + Sbjct: 6 IEGKIAFITGAA--QGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSL--KAEARHAEA 61 Query: 63 LPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNISA 122 P DV + + I++E+G I + + G S + + ++++ Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVAGVLR----PGLIHSLSDEEWEATFSVNS 117 Query: 123 FSLTAVAREAKKVMT--EGGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLANDLGQ 180 + +R K M G+I+T+ + +KA+ K L +L + Sbjct: 118 TGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE 177 Query: 181 HGIRVNAISAGPIRT-----LSAKGVGDFNSILREIEE---RAPLRRTTTQEEVGDTAVF 232 + IR N +S G T L A G I +E PL++ ++ D +F Sbjct: 178 YNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLF 237 Query: 233 LFSDLARGVTGENIHVDSG 251 L S A +T N+ VD G Sbjct: 238 LVSGQAGHITMHNLCVDGG 256
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.6 bits (66), Expect = 0.009 Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 6/80 (7%) Query: 29 LELAAPKTKRIILTNFENEDRKEESNRNENVVSSAVEEVIEQEEQQQEQEQEQEE----- 83 + A K TN E E+ + + V ++E+ + E E+ QE Sbjct: 1069 AKEAKSNVKANTQTN-EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTS 1127 Query: 84 QVEEKTEEEEQVQEQQEPVR 103 QV K E+ E VQ Q EP R Sbjct: 1128 QVSPKQEQSETVQPQAEPAR 1147
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 29.7 bits (66), Expect = 0.002 Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 21/127 (16%) Query: 6 IFFLLTCLLLVASTTYIICNKREQV--PPMLVWEGQEYYVTNEPAKAEEVGQRLGEVTKK 63 I LLT + ++A + N R V PP + GQ V E V GEVTK Sbjct: 8 ISLLLTSVAVLAD---VQINIRGNVYIPPCTINNGQNIVVDFGNINPEHVDNSRGEVTKN 64 Query: 64 IETSEKPIKN--------------SESNIVQEKTEVFTM-IEEEKGPHSPLIIKEPDGEE 108 I S P K+ ++N++ F + + + KG +PL + G Sbjct: 65 ISIS-CPYKSGSLWIKVTGNTMGVGQNNVLATNITHFGIALYQGKGMSTPLTLGNGSGNG 123 Query: 109 YRIVRAM 115 YR+ + Sbjct: 124 YRVTAGL 130
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.3 bits (63), Expect = 0.009 Identities = 10/36 (27%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Query: 69 EDRLKHLPEGSHQTVVIDVRGPDETG-EILKQIREE 103 + + G VV DV PDE ++L +I++ Sbjct: 37 ATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKA 72
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.7 bits (74), Expect = 0.001 Identities = 15/56 (26%), Positives = 22/56 (39%) Query: 12 KRYGLKAVIRELNIEITEGKIIGLVGDNGSGKTTLLKMIAGLQHPSEGSITIAGKK 67 K + V R + + L G G GK+TL+ + GL S+ I K Sbjct: 578 KYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGK 633
>CHLAMIDIAOM6#Chlamydia cysteine-rich outer membrane protein 6 signature. Length = 547 Score = 39.3 bits (91), Expect = 4e-04 Identities = 24/63 (38%), Positives = 37/63 (58%), Gaps = 7/63 (11%) Query: 1130 SNTVSTQINLANVVIVKQVDLTIAD---VGQPITYTIALANPGNTPANNVVVTDILPPGT 1186 + +V+T IN V QV + AD V +P+ Y I+++NPG+ +VVV D L PG Sbjct: 305 TASVTTVINEPCV----QVSIAGADWSYVCKPVEYVISVSNPGDLVLRDVVVEDTLSPGV 360 Query: 1187 TLV 1189 T++ Sbjct: 361 TVL 363 Score = 37.4 bits (86), Expect = 0.002 Identities = 73/382 (19%), Positives = 135/382 (35%), Gaps = 101/382 (26%) Query: 1956 YTVLLENIGNTTATNIIFTDPIPNHTVFIEDSVRVGGILLPGVNPANGIPIGDIIAGDFI 2015 Y + + N G TA N++ +P+P+ G +GD+ G+ Sbjct: 229 YKINIVNQGTATARNVVVENPVPD------------GYAHSSGQRVLTFTLGDMQPGE-- 274 Query: 2016 NITFRVQVVSIPNPIFTIGPGGPNSPVVNGASINYQFMTGPNLPLASRSTTSNPVSTQIN 2075 + T V+ + N A+++Y G + AS +T N Q++ Sbjct: 275 HRTITVEFCPLKR-----------GRATNIATVSY---CGGHKNTASVTTVINEPCVQVS 320 Query: 2076 SGEIALVKSVDKTFVTIGDTLSYSISLSNPGNVTSQNIIFTDVLPEGITFISGTLTNDSG 2135 + D ++V + Y IS+SNPG++ ++++ D L G+T + Sbjct: 321 ------IAGADWSYVC--KPVEYVISVSNPGDLVLRDVVVEDTLSPGVTVLEA------- 365 Query: 2136 TQQIGNPATGIQIGNINPGSTATIVINALVTNIPSINPISNFSSVQFAHVVDPSQPSVSQ 2195 G A I N +V + +NP S+Q+ +V P Sbjct: 366 -----------------AG--AQISCNKVVWTVKELNP---GESLQYKVLVRAQTPG--- 400 Query: 2196 TNLSNTVSTTIKSAILTTTKSADKSV------------------ISVGDTITYTTTITNT 2237 +N V S T T A+ + + VG+ Y +TN Sbjct: 401 -QFTNNVVVKSCSDCGTCTSCAEATTYWKGVAATHMCVVDTCDPVCVGENTVYRICVTNR 459 Query: 2238 GNTAAANI----KFT-------SAIPANTTFIPNSVTINGVQQSGVQPAL--GVNIPNIA 2284 G+ N+ KF+ + P T N+V + + + G + + V + ++ Sbjct: 460 GSAEDTNVSLMLKFSKELQPVSFSGPTKGTITGNTVVFDSLPRLGSKETVEFSVTLKAVS 519 Query: 2285 PGETV-TVTFQVNVLSVPSSSS 2305 G+ + L+VP S + Sbjct: 520 AGDARGEAILSSDTLTVPVSDT 541 Score = 35.8 bits (82), Expect = 0.005 Identities = 36/160 (22%), Positives = 62/160 (38%), Gaps = 30/160 (18%) Query: 2884 IVYSVTITNSGNVNATNVIFTDVIPDGTSFEPNSFTLNGTIIENANIITGVPIGDIAPNE 2943 +VY + I N G A NV+ + +PDG + L T +GD+ P E Sbjct: 227 VVYKINIVNQGTATARNVVVENPVPDGYAHSSGQRVLTFT------------LGDMQPGE 274 Query: 2944 SAI--VEFHITSNEIPAINPITNQASVSFQHIVNPANPPVSKNITSNSVTTTIESAILTT 3001 VEF TN A+VS+ + + SVTT I + Sbjct: 275 HRTITVEFCPLKR-----GRATNIATVSY----------CGGHKNTASVTTVINEPCVQV 319 Query: 3002 TKIGDKAFATIGDTITYTTTITNIGNIPANNVIFSDPIPS 3041 + I ++ + + Y +++N G++ +V+ D + Sbjct: 320 S-IAGADWSYVCKPVEYVISVSNPGDLVLRDVVVEDTLSP 358 Score = 33.9 bits (77), Expect = 0.018 Identities = 35/180 (19%), Positives = 69/180 (38%), Gaps = 27/180 (15%) Query: 4316 IAVKTTPIQYADLQTIIPYTISITNNGNIQVENIIVTDIIPANTNFIENSVIVNGNTRPN 4375 I VK + A L+ + Y I+I N G N++V + +P +G + Sbjct: 211 ICVKQEGPENACLRCPVVYKINIVNQGTATARNVVVENPVP------------DGYAHSS 258 Query: 4376 DNPLSGIPIDNILPNTTATVLFQVRVTSIPQT-NPISNTSTIEYEYTVGDQPPITKTIIS 4434 + + ++ P T+ V P +N +T+ Y + +T I Sbjct: 259 GQRVLTFTLGDMQPGEHRTIT----VEFCPLKRGRATNIATVSYCGGHKNTASVTTVINE 314 Query: 4435 SAALTEINHANLNSNKAVDLAFAMVGDTLTYTITLNQTGNVAANDVIIQDMIPQGTTFIE 4494 I A+ ++ V + Y I+++ G++ DV+++D + G T +E Sbjct: 315 PCVQVSIAGAD----------WSYVCKPVEYVISVSNPGDLVLRDVVVEDTLSPGVTVLE 364
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 49.8 bits (119), Expect = 9e-09 Identities = 49/261 (18%), Positives = 96/261 (36%), Gaps = 15/261 (5%) Query: 56 WSGSIVDRLNKRSIMLITDIIRAALIGCIPLFDSIWAIYIFIFLTRIATSFFDPASFSYK 115 G++ DR +R ++L++ A + +W +YI + I + + +Y Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYI 120 Query: 116 TMLIRAEERAQFNAWSNFCTSGAFIIGPALAGILLTTHSAT---FVIYCNSLSFLLSTIF 172 + +ERA+ + + C + GP L G++ N L+FL F Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTG-CF 179 Query: 173 IYFLPNIALQTKQNEEVANTFVQTLRNDWKQVFSFARTETYIILIFVLFQATMLVAMALD 232 + + + E N F +AR T + + +F LV Sbjct: 180 LLPESHKGERRPLRREALNPLAS---------FRWARGMTVVAALMAVFFIMQLVGQVPA 230 Query: 233 SQEVVFTKQVLLLSNMEYSMLVSITGAAY-VFGSFLVSLFAKRLPIQYCIGFGMIFTAIG 291 + V+F + + ++ G + + + + A RL + + GMI G Sbjct: 231 ALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTG 290 Query: 292 YVIFAFSNSFIVAAGGFILLG 312 Y++ AF+ +A +LL Sbjct: 291 YILLAFATRGWMAFPIMVLLA 311
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.7 bits (111), Expect = 9e-08 Identities = 56/292 (19%), Positives = 109/292 (37%), Gaps = 17/292 (5%) Query: 59 LPQLLLSPFIGGVVDRFSKKNIMIFTDITRGILVLTYILASYK-IEIIFIANICLSVLSC 117 L Q +P +G + DRF ++ +++ + G V I+A+ + +++I I ++ ++ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLA--GAAVDYAIMATAPFLWVLYIGRI-VAGITG 110 Query: 118 LFEPAKQATLKNIVHENHFVTANSLSSTMNGFMSIMGASLGGIIAQ-SLHIEFAF--LVN 174 A + +I + S GF + G LGG++ S H F +N Sbjct: 111 ATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALN 170 Query: 175 SLSYFISAYFIYSMCIPSHNTCNKKKAFLTDIKDGYTYILQTKIILTLILVGISWGLIGG 234 L++ + + ++ + + + ++ L+ V L+G Sbjct: 171 GLNFLTGCFLLPESHKGERRPLRREA---LNPLASFRWARGMTVVAALMAVFFIMQLVGQ 227 Query: 235 AYQLLLTIYAEKIFH---TNIGILYTVQGA-GLMIGSLLVNLYISHNKEKIKKAFGWACF 290 L I+ E FH T IGI G + +++ + E+ G Sbjct: 228 VPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIAD 287 Query: 291 LQGVFFLGFILSSQLIFGLTTLLCMRIAGGIIVPLDTTLLQTYTRENMIGKV 342 G L F + F + LL +GGI +P +L E G++ Sbjct: 288 GTGYILLAFATRGWMAFPIMVLL---ASGGIGMPALQAMLSRQVDEERQGQL 336
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 63.4 bits (154), Expect = 6e-14 Identities = 30/127 (23%), Positives = 56/127 (44%), Gaps = 17/127 (13%) Query: 110 SVVIVDNLIFDTGDANVKPEAKEIISQLVGFFQSVPNP---IVVEGHTDSRPIHNDKFPS 166 + +++F+ A +KPE + + QL ++ +VV G+TD +D + Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRI--GSDAY-- 269 Query: 167 NWELSSARAANMIHHLIEVYNVDDKRLAAVGYADTKPVVPN---------DSPQNWEKNR 217 N LS RA +++ +LI + +++A G ++ PV N +R Sbjct: 270 NQGLSERRAQSVVDYLIS-KGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDR 328 Query: 218 RVVIYIK 224 RV I +K Sbjct: 329 RVEIEVK 335
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.6 bits (204), Expect = 9e-22 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 2/112 (1%) Query: 4 KILVVDDAMFMRTMIKNLLKSNSEFEVIGEAENGVEAIQKYKELQPDIVTLDITMPEMDG 63 ILV DD +RT++ L + + N + D+V D+ MP+ + Sbjct: 5 TILVADDDAAIRTVLNQAL--SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 64 LEALKEIIKIDASAKVVICSAMGQQGMVLDAIKGGAKDFIVKPFQADRVIEA 115 + L I K V++ SA + A + GA D++ KPF +I Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 55.7 bits (134), Expect = 1e-11 Identities = 23/71 (32%), Positives = 40/71 (56%) Query: 473 DTSILQNVEMNVKFVFGSTVKTIQDILSLQENEAVVLDEDIDEPIRIYVNDVLVAYGELV 532 D ++ ++ + + G T TI+++L L + V LD EP+ I +N L+A GE+V Sbjct: 53 DIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVV 112 Query: 533 NVDGFFGVKVT 543 V +GV++T Sbjct: 113 VVADKYGVRIT 123
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.9 bits (77), Expect = 0.002 Identities = 18/126 (14%), Positives = 51/126 (40%), Gaps = 1/126 (0%) Query: 301 EQKTEEDKKIEEPENEDKLENKLEDKKVTEKQEDSKVEISLPEEKTPVVQIPKKEEKVND 360 + EE K+E + ++ + + E+ E + + E P V I + + + N Sbjct: 1105 TVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNT 1164 Query: 361 LIKEPLKEKEKITYVIKEPLTDNKEVNKTKAQKDKDNNNQVISKKKEKKEEPEEKKEAKS 420 + ++ + +++P+T++ VN + + N + + E K + + Sbjct: 1165 TADTE-QPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRH 1223 Query: 421 EQGIQA 426 + +++ Sbjct: 1224 RRSVRS 1229 Score = 29.3 bits (65), Expect = 0.045 Identities = 26/109 (23%), Positives = 44/109 (40%), Gaps = 7/109 (6%) Query: 22 LQSKAEEQNVP-EQNINEV-NVQEENKEVQEQLEQVEMKQDKEEQQEAKNEQETEKKIET 79 +K + NV NEV E KE Q + + E++++AK ETEK E Sbjct: 1067 EVAKEAKSNVKANTQTNEVAQSGSETKETQTT--ETKETATVEKEEKAK--VETEKTQEV 1122 Query: 80 DQGVITVNKPELKVGEEVLVTIEPKEKNVQSIKGILRLPKNGDQYEQER 128 + V + P+ + E V EP +N ++ + + E+ Sbjct: 1123 PK-VTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQ 1170
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 104 bits (260), Expect = 3e-26 Identities = 72/249 (28%), Positives = 112/249 (44%), Gaps = 14/249 (5%) Query: 4 SDYNTPLSGLLAAQMGLQTTKQNLSNIHTPGYVRQMVNYGSAGASQGYSPEQKIGYGVQT 63 S N +SGL AAQ L T N+S+ + GY RQ A ++ G +G GV Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLG--AGGWVGNGVYV 59 Query: 64 LGVDRITDEVKTKQFNDQLSQLSYYNYMNSTLSRVESMVGTTGKNSLSSLMDGFFNAFRE 123 GV R D T Q +Q S +S++++M+ T+ SL++ M FF + + Sbjct: 60 SGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTS-SLATQMQDFFTSLQT 118 Query: 124 VAKNPEQPNYYDTLISETGKFTSQVNRLAKSLDTAEAQTTEDIEAHVNEFNRLAGSLAEA 183 + N E P LI ++ +Q + L + Q I A V++ N A +A Sbjct: 119 LVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASL 178 Query: 184 NKKI----GQAGTQVPNQLLDERDRIITEMSKYANIEVS---YESMNPNIASVRMNGVLT 236 N +I G PN LLD+RD++++E+++ +EVS + N +A NG Sbjct: 179 NDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMA----NGYSL 234 Query: 237 VNGQDTYPL 245 V G L Sbjct: 235 VQGSTARQL 243 Score = 54.2 bits (130), Expect = 6e-10 Identities = 19/51 (37%), Positives = 35/51 (68%) Query: 380 LLEGIQQEKMGIEGVNMEEEMVNLMAFQKYFVANSKAITTMNEVFDSLFSI 430 ++ + ++ I GVN++EE NL FQ+Y++AN++ + T N +FD+L +I Sbjct: 495 VVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 1e-06 Identities = 15/36 (41%), Positives = 24/36 (66%) Query: 5 LYTSITGMNAAQNALSVTSNNIANAQTVGYKKQKAI 40 + +++G+NAAQ AL+ SNNI++ GY +Q I Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI 39 Score = 37.6 bits (87), Expect = 9e-05 Identities = 10/39 (25%), Positives = 26/39 (66%) Query: 397 SNVDLSVEFVDLMLYQRGFQGNAKVIKVSDEVLNEVVNL 435 S V+L E+ +L +Q+ + NA+V++ ++ + + ++N+ Sbjct: 507 SGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 41.5 bits (97), Expect = 2e-06 Identities = 23/101 (22%), Positives = 34/101 (33%), Gaps = 11/101 (10%) Query: 444 DNEQIQLALIREDIRQLINQGMISQAKYLISEYEKTFPITSEIYQMKGIVAFSENNYLDA 503 D ++ QLA+ + G IS T E + Y DA Sbjct: 7 DTQEYQLAME-----SFLKGGGTIAMLNEISSD------TLEQLYSLAFNQYQSGKYEDA 55 Query: 504 ENFFKLALKLYHFDVDALFNLGYLYEVQEQYDRAVQNYNLA 544 F+ L H+D LG + QYD A+ +Y+ Sbjct: 56 HKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYG 96
>FLAGELLIN#Flagellin signature. Length = 507 Score = 125 bits (314), Expect = 9e-35 Identities = 76/282 (26%), Positives = 130/282 (46%), Gaps = 18/282 (6%) Query: 1 MRINTNINSMRTQEYMRQNQDKMNVSMNRLSSGKRINSAADDAAGLAIATRMRARQSGLE 60 INTN S+ TQ + ++Q ++ ++ RLSSG RINSA DDAAG AIA R + GL Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLT 61 Query: 61 KASQNTQDGMSLIRTAESAMNSVSNILTRMRDIAVQSSNGTNTAENQSALQKEFAELQEQ 120 +AS+N DG+S+ +T E A+N ++N L R+R+++VQ++NGTN+ + ++Q E + E+ Sbjct: 62 QASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEE 121 Query: 121 IDYIAKNTEFNDKNLLAGTGAVTIGSTSISGAEISIETLDSSATNQQITIKLANTTAEKL 180 ID ++ T+FN +L+ + I + G + ITI L + L Sbjct: 122 IDRVSNQTQFNGVKVLSQDNQMKIQVGANDG--------------ETITIDLQKIDVKSL 167 Query: 181 GIDATTSN----ISISGAASALAAISALNTALNTVAGNRATLGATLNRLDRNVENLNNQA 236 G+D N ++ S+ ++ +T R + + D + ++ Sbjct: 168 GLDGFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKV 227 Query: 237 TNMASAASQIEDADMAKEMSEMTKFKILNEAGISMLSQANQT 278 A+ D ++ K + A Sbjct: 228 YVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 86.3 bits (213), Expect = 4e-21 Identities = 62/259 (23%), Positives = 107/259 (41%), Gaps = 7/259 (2%) Query: 36 INSAADDAAGLAIATRMRARQSGLEKASQNTQDGMSLIRTAESAMNSVSNILTRMRDIAV 95 + AG A A + G ++ G++ ++ + + T + V Sbjct: 249 LFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVSTTINGEKV 308 Query: 96 QSSNGTNTAENQSALQKEFAELQEQID-YIAKNTEFNDKN------LLAGTGAVTIGSTS 148 + TA + + + F+DK L + S Sbjct: 309 TLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGES 368 Query: 149 ISGAEISIETLDSSATNQQITIKLANTTAEKLGIDATTSNISISGAASALAAISALNTAL 208 + T +++ + K G+ + + + S ++++++AL Sbjct: 369 KITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSAL 428 Query: 209 NTVAGNRATLGATLNRLDRNVENLNNQATNMASAASQIEDADMAKEMSEMTKFKILNEAG 268 + V R++LGA NR D + NL N TN+ SA S+IEDAD A E+S M+K +IL +AG Sbjct: 429 SKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAG 488 Query: 269 ISMLSQANQTPQMVSKLLQ 287 S+L+QANQ PQ V LL+ Sbjct: 489 TSVLAQANQVPQNVLSLLR 507
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.021 Identities = 8/42 (19%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 122 LTKKY-NIQKIRSSNEGKYEDIIDRVSHTYGIPKTLIQKMIE 162 + Y + I+ + ++E+ I+ +P L+Q ++E Sbjct: 224 VVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVE 265
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 58.8 bits (142), Expect = 2e-14 Identities = 22/94 (23%), Positives = 51/94 (54%) Query: 13 LEDFAGKRNEASKAHIDTVSDISIELGVKLGKASITLGDVKQLKVGDVLEVEKNLGHKVD 72 + G + ID + DI ++L V+LG+ +T+ ++ +L G V+ ++ G +D Sbjct: 39 FQQLGGGDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLD 98 Query: 73 VYLSNMKVGIGEAIVMDEKFGIIISEIEADKKQA 106 + ++ + GE +V+ +K+G+ I++I ++ Sbjct: 99 ILINGYLIAQGEVVVVADKYGVRITDIITPSERM 132
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 164 bits (417), Expect = 2e-52 Identities = 75/239 (31%), Positives = 136/239 (56%), Gaps = 2/239 (0%) Query: 14 FVFSIVFSIIFVNPAYAAQNGFINFENGKEFTSN--SSVQLFALVTLLSLSSSIVLLFTH 71 + + + P AQ I + + VQ +T L+ +I+L+ T Sbjct: 4 LLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTS 63 Query: 72 FTYFMIVLGITRQGLGVMNLPPNQVLVGLALFLSLFTMQPVLGQLKSDVWDPMTKEKITV 131 FT +IV G+ R LG + PPNQVL+GLALFL+ F M PV+ ++ D + P ++EKI++ Sbjct: 64 FTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISM 123 Query: 132 SQAAETTAPIMKEYMSKHTYKHDLKMMLKVRGEELPKDLKDLSLFTLVPSFTLTQIQKGL 191 +A E A ++E+M + T + DL + ++ + + + + L+P++ ++++ Sbjct: 124 QEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAF 183 Query: 192 LTGMFIYLAFVFIDLIISTLLMYLGMMMVPPMILSLPFKILIFVYLGGYTKIVDIMFKT 250 G I++ F+ IDL+I+++LM LGMMMVPP ++LPFK+++FV + G+ +V + ++ Sbjct: 184 QIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQS 242
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 41.7 bits (98), Expect = 1e-08 Identities = 15/81 (18%), Positives = 35/81 (43%) Query: 4 SPIIDIFQTFFYKGVMILMPVAGVSMIVVIIIAVIMAMMQIQEQTLTFLPKMASIVLVII 63 ++ Y +++ V+ I+ +++ + + Q+QEQTL F K+ + L + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 ILGPWMFQELTTLILDLFDKI 84 +L W + L + + Sbjct: 62 LLSGWYGEVLLSYGRQVIFLA 82
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 96.0 bits (239), Expect = 7e-26 Identities = 51/233 (21%), Positives = 113/233 (48%), Gaps = 1/233 (0%) Query: 10 FFAFCRITSFLYFLPFFSGRSIPAMAKVTFGLALSITVADQVDVSHIKTVWDVAA-YAGT 68 F+ R+ + + P S RS+P K+ + ++ +A + + + A A Sbjct: 17 FWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVPVFSFFALWLAVQ 76 Query: 69 QIVIGLSLSKIVEMLWNIPKMAGHILDFDIGLSQASLFDVNAGSQSTLLSTIFDIFFLII 128 QI+IG++L ++ + + AG I+ +GLS A+ D + +L+ I D+ L++ Sbjct: 77 QILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLALLL 136 Query: 129 FISLGGINYFVATILKSFQYTEAISKLLTTSFLDSLLATLLFAITSAVEIALPLMGSLFI 188 F++ G + ++ ++ +F + L ++ +L + + +ALPL+ L Sbjct: 137 FLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLALPLITLLLT 196 Query: 189 INFVLILIAKNAPQLNVFMNAYVIKITCGILFIAMSVPMLGYVFKNMTDVLLE 241 +N L L+ + APQL++F+ + + +T GI +A +P++ +++ + Sbjct: 197 LNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIFN 249
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 289 bits (742), Expect = 2e-98 Identities = 92/343 (26%), Positives = 186/343 (54%), Gaps = 2/343 (0%) Query: 4 DNKTEKATPQKRKKSREEGNIARSKDLNNLFSILVLAVVVYFFGDWLGFEIANSVSVLFD 63 KTE+ TP+K + +R++G +A+SK++ + I+ L+ ++ D+ + + + + Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAE 62 Query: 64 QIGKNTDS--TEYFYMMGILLLKVSAPILILVYAFHLFNYMIQVGFLFSSKVIKPKASRI 121 Q + + + + P+L + + ++++Q GFL S + IKP +I Sbjct: 63 QSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKI 122 Query: 122 NPKNYFTRLFSRKSLVDILKSLFYMGLIGYVAYVLFKKNLEKIVSMIGFNWTASLTEIIR 181 NP R+FS KSLV+ LKS+ + L+ + +++ K NL ++ + + + Sbjct: 123 NPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQ 182 Query: 182 QIKFIFLAILIILIVLSIIDFIYQKWEYEQDIKMKKEEVKQEHKDNEGDPQVKGKRKNFM 241 ++ + + + +V+SI D+ ++ ++Y +++KM K+E+K+E+K+ EG P++K KR+ F Sbjct: 183 ILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQFH 242 Query: 242 HAILQGTIAKKMDGATFIVNNPTHISVVLRYNKHVDAAPIVVAKGEDELALYIRTLAREQ 301 I + + + ++ +V NPTHI++ + Y + P+V K D +R +A E+ Sbjct: 243 QEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEE 302 Query: 302 EIPMVENRPLARSLYYQVEEDETIPEDLYVAVIEVMRYLIQTN 344 +P+++ PLAR+LY+ D IP + A EV+R+L + N Sbjct: 303 GVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQN 345
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 28.4 bits (63), Expect = 0.033 Identities = 11/47 (23%), Positives = 24/47 (51%) Query: 203 NGVGTVKNYMLENSNVDMTKEMADLMTDQRMISASQRVMTSFDKIYE 249 N V + N S V++ +E +L Q+ A+ +V+ + + I++ Sbjct: 494 NVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 540
>DPTHRIATOXIN#Diphtheria toxin signature. Length = 567 Score = 27.8 bits (61), Expect = 0.039 Identities = 26/113 (23%), Positives = 49/113 (43%), Gaps = 16/113 (14%) Query: 63 EQGEIVHYIKDGAQVKLGPVKLEINWERRHNLMRHHSLLHLIGAVVYEKYGALCTGNQIY 122 E V YI + Q K V+LEIN+E R + +YE C GN++ Sbjct: 174 EGSSSVEYINNWEQAKALSVELEINFETRGKRGQD---------AMYEYMAQACAGNRVR 224 Query: 123 PDKA------RIDFNELQELSSVEVEGIVKEVNKLIEQNKEISTRYMSREEAE 169 +D++ +++ + ++E + KE + + E + +S E+A+ Sbjct: 225 RSVGSSLSCINLDWDVIRDKTKTKIESL-KEHGPIKNKMSESPNKTVSEEKAK 276
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 334 bits (859), Expect = e-120 Identities = 209/213 (98%), Positives = 212/213 (99%) Query: 1 MEAFIRSDQYNFIKSQAYILANGHATANDRGVIQALKSLAIEKIIHVFENLTDEQKELID 60 MEAFIRSDQYNFIKSQAYILANGHATANDRGVIQALKSLAIEKIIHVFENLTDEQKELID Sbjct: 7 MEAFIRSDQYNFIKSQAYILANGHATANDRGVIQALKSLAIEKIIHVFENLTDEQKELID 66 Query: 61 TVLTVQNREDAESFLTKINPYVIPFQEVTAQTLKKLFPKAKKLKLPDMEEMDMKEISYLS 120 TVLTVQNREDAESFL KINPYVIPFQEVTAQTLKKLFPKAKKLKLPDMEE+DMKE+SYLS Sbjct: 67 TVLTVQNREDAESFLLKINPYVIPFQEVTAQTLKKLFPKAKKLKLPDMEELDMKELSYLS 126 Query: 121 WVDKGSSRKFIIAKNDKNKFVGLQGTFQSLNKKSICSLCHGHEEVGMFLVEIKGDIPGTF 180 W+DKGSSRKFIIAKNDKNKFVGLQGTFQSLNKKSICSLCHGHEEVGMFLVEIKGDIPGTF Sbjct: 127 WIDKGSSRKFIIAKNDKNKFVGLQGTFQSLNKKSICSLCHGHEEVGMFLVEIKGDIPGTF 186 Query: 181 VKKGNYICKDGVACNQNMKSLDKLQDFIERLKK 213 VKKGNYICKDGVACNQNMKSLDKLQDFIERLKK Sbjct: 187 VKKGNYICKDGVACNQNMKSLDKLQDFIERLKK 219
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 88.2 bits (218), Expect = 5e-23 Identities = 68/263 (25%), Positives = 121/263 (46%), Gaps = 21/263 (7%) Query: 2 LKGKVALVTGASRGIGRAIAKRLANDGALV-AIHYGNRKEEAEETVYEIQSNGGSAFSIG 60 ++GK+A +TGA++GIG A+A+ LA+ GA + A+ Y K E + + ++ AF Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP-- 63 Query: 61 ANLESLHGVEALYSSLDNELQNRTGSTKFDILINNAGIGPGAFIEETTEQFFDRMVSVNA 120 A++ ++ + + ++ E+ DIL+N AG+ I +++ ++ SVN+ Sbjct: 64 ADVRDSAAIDEITARIEREMG------PIDILVNVAGVLRPGLIHSLSDEEWEATFSVNS 117 Query: 121 KAPFFIIQQALSRLRD--NSRIINISSAATRISLPDFIAYSMTKGAINTMTFTLAKQLGA 178 F + + D + I+ + S + AY+ +K A T L +L Sbjct: 118 TGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE 177 Query: 179 RGITVNAILPGFVKTDMNAELLSDP---------MMKQYATTISAFNRLGEVEDIADTAA 229 I N + PG +TDM L +D ++ + T I +L + DIAD Sbjct: 178 YNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIP-LKKLAKPSDIADAVL 236 Query: 230 FLASPDSRWVTGQLIDVSGGSCL 252 FL S + +T + V GG+ L Sbjct: 237 FLVSGQAGHITMHNLCVDGGATL 259
>adhesinb#Adhesin B signature. Length = 310 Score = 214 bits (547), Expect = 4e-70 Identities = 75/319 (23%), Positives = 137/319 (42%), Gaps = 20/319 (6%) Query: 3 KRLTIFSFLLIFTLIFTGCSNTKEGNAKKDGKLTVYTTIFPLADFAKKIGGDYVTVEAIY 62 K+ LL+ + CS+ K KL V T +AD K I GD + + +I Sbjct: 2 KKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSIV 61 Query: 63 PPGADSHTFEPSQKQTVKVAKADLFVYNGAELE-----PFAEKMEKSLQKENVKIVNASK 117 P G D H +EP + K ++ADL YNG LE F + +E + +KEN S+ Sbjct: 62 PVGQDPHEYEPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVSE 121 Query: 118 GIELRTSTEEEHHDHGDGHKEDEHHHDKDPHIWLDPTLAMKQAEKIKNALVALQPDHKQE 177 G+++ + DPH WL+ + A+ I L P +K+ Sbjct: 122 GVDVIYLEGQSEKGKE------------DPHAWLNLENGIIYAQNIAKRLSEKDPANKET 169 Query: 178 FEKNFAALQTKFTDLDDQFKAVVAN--AKTKDILVSHAAYGYWEQRYGLKQIAIAGISAS 235 +EKN A K + LD + K N + K I+ S + Y+ + Y + I I+ Sbjct: 170 YEKNLKAYVEKLSALDKEAKEKFNNIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTE 229 Query: 236 DEPSQKQLADITKTVKEHNLKYILFETFSTPKVASVIQKETGTKVLRLNHLATISEDDAK 295 +E + Q+ + + +++ + + E+ + + K+T + +++E + Sbjct: 230 EEGTPDQIKTLVEKLRKTKVPSLFVESSVDDRPMKTVSKDTNIPIYAKIFTDSVAEKGEE 289 Query: 296 NNKDYFTLMEENVNTLKEA 314 + Y+++M+ N+ + E Sbjct: 290 GD-SYYSMMKYNLEKIAEG 307
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 37.2 bits (86), Expect = 6e-06 Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 5/103 (4%) Query: 27 SREEASSLFQKMKEENYKLFSLRNEENEVVSLAGVAICTNFYNEKHVFVYDLVTAEAHRS 86 E+ ++EE F E N + + I +N+ + + D+ A+ +R Sbjct: 49 QYEDDDMDVSYVEEEGKAAFLYYLENNCI---GRIKIRSNW--NGYALIEDIAVAKDYRK 103 Query: 87 KGYGNVLLSYVEKWGKEKGCSSIVLTSAFPRIDAHRFYEREGF 129 KG G LL +W KE ++L + I A FY + F Sbjct: 104 KGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 28.6 bits (63), Expect = 0.017 Identities = 16/42 (38%), Positives = 23/42 (54%) Query: 43 YFSFSMQEYSVYKEKMQTRLKEEPLSNLIIENNGQVIGTVGF 84 + SFS+Q S YKE+M + EE LS + N + I G+ Sbjct: 220 FISFSLQGNSKYKEEMDAKKLEEILSLKVDANPDKYIKATGY 261
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.1 bits (65), Expect = 0.019 Identities = 20/109 (18%), Positives = 39/109 (35%), Gaps = 6/109 (5%) Query: 131 REIDKENNEAAYLLASANFRIGKYQEAVQNFEQALANNAKGIEPYKKDAMRDLAVSHMKM 190 EI + E Y LA ++ GKY++A + F+ ++ Y L M Sbjct: 29 NEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCV-----LDHYDSRFFLGLGACRQAM 83 Query: 191 KEFEKAEDVIVKMSTKTNEDKAIVSYLKGQLSTATVQLEKAESFFKEAI 239 +++ A + ++ + + +L +AES A Sbjct: 84 GQYDLAIHSYSYGAIMDIKE-PRFPFHAAECLLQKGELAEAESGLFLAQ 131
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.4 bits (92), Expect = 2e-05 Identities = 27/175 (15%), Positives = 66/175 (37%), Gaps = 30/175 (17%) Query: 5 LEIKVKPEQLEQIAKNISEMQTHSQNIQQNLN--QSMFSIQMQWQGATSQHFY----GEY 58 L + K + + I+ + S+ + L+ S+ + A ++H +Y Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH-----KQAIAKHAVLEQENKY 261 Query: 59 MRSMRLMESYIRNLQVTEKELRRIAQKFRQADEEYQKKQNEKLKEAHKK--EKKNEKSWW 116 + ++ + Y L+ E E+ ++++ + ++ + +KL++ E + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELA-- 319 Query: 117 EKGIEGAAEFIGVNDAIRAVTGKDPITG--KELS--TKERLIAAGWTLLNFVPVG 167 E IRA P++ ++L T+ ++ TL+ VP Sbjct: 320 ------KNEERQQASVIRA-----PVSVKVQQLKVHTEGGVVTTAETLMVIVPED 363
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 103 bits (259), Expect = 6e-28 Identities = 31/115 (26%), Positives = 62/115 (53%) Query: 4 RILIVEDEEKIARVVQLELEFEGYESEIAKTGTEAMEKFGNGNWDLILLDVMLPNISGLE 63 IL+ +D+ I V+ L GY+ I G+ DL++ DV++P+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 VLRRIRLKNAVIPIILLTARDSVVDKVSGLDQGASDYITKPFQIEELLARIRACL 118 +L RI+ +P+++++A+++ + + ++GA DY+ KPF + EL+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 26.4 bits (58), Expect = 0.007 Identities = 11/30 (36%), Positives = 16/30 (53%), Gaps = 3/30 (10%) Query: 18 VTFFGPYNEVITNVS---IINQLSTPKCQT 44 ++FF NE++ NVS I N + P T Sbjct: 22 LSFFSVLNEMVLNVSLPDIANDFNKPPAST 51
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 31.3 bits (71), Expect = 0.005 Identities = 16/46 (34%), Positives = 24/46 (52%) Query: 121 EDLLAMTDYISKRLGKEKAILIGHSYGTYIGMQAANKAPEKYEAYV 166 +D LA+ D G +K ILIG+S+G + N+ P +Y V Sbjct: 101 QDTLAIIDKYQAEFGTQKVILIGYSFGAEVIPFVLNEMPARYRKNV 146
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.3 bits (76), Expect = 0.002 Identities = 24/119 (20%), Positives = 45/119 (37%), Gaps = 8/119 (6%) Query: 49 ATMTQIMIALPAL--IFF--LLVGTVVDRFDRQRICTVSNICCSLCNIGILISLYYGMII 104 AT I +A + ++ G V R +R + I I + + M Sbjct: 245 ATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAF 304 Query: 105 LVFLFLFLENACIQFFSPSEQSMIQGVVESDQYGAAAGINQMVNSLYALFGVGIATMVY 163 + + L A P+ Q+M+ V+ ++ G G + SL ++ G + T +Y Sbjct: 305 PIMVLL----ASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIY 359 Score = 31.7 bits (72), Expect = 0.005 Identities = 28/198 (14%), Positives = 67/198 (33%), Gaps = 28/198 (14%) Query: 173 LVNTLTFIMSGILIQTISIPEKVRLPNGRTKWKEVNLKMLITEFKEGIRYIYQNETLKKL 232 +N L F+ L+ K + L+ R+ + L Sbjct: 168 ALNGLNFLTGCFLLPE------------SHKGERRPLRREALNPLASFRWARGMTVVAAL 215 Query: 233 LLGFIVFGLLNGILSVSTTYIL----KYKLAPATYESLAMVGGVVGGISLLIGSIVATSI 288 + F + L+ + + +++ ++ T G++ ++ + + + Sbjct: 216 MAVFFIMQLVGQVPA--ALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAM---ITGPV 270 Query: 289 GKKYAPKPIIVFGMAGSGIFFGMCYFVNYVWSFY---VCIAFATFFLPFINVAIMGWMYE 345 + + ++ GM G + + F W + V +A +P A+ + Sbjct: 271 AARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMP----ALQAMLSR 326 Query: 346 IVEESFMGRVQSLLSPLT 363 V+E G++Q L+ LT Sbjct: 327 QVDEERQGQLQGSLAALT 344
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 83.1 bits (205), Expect = 6e-22 Identities = 35/164 (21%), Positives = 66/164 (40%), Gaps = 10/164 (6%) Query: 20 KSTKETILEVATRLFLTQNYQVVSMDEVAKVCGVTKATVYYYFSTKADLFTATMIQMMIR 79 + T++ IL+VA RLF Q S+ E+AK GVT+ +Y++F K+DLF+ Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 80 IRENMSQILS-TNNTLEERLLNFAKVYLHATMDIDMKNFMKDAKLSLSEEQLKELKK--- 135 I E + + L L +T+ + + + + + E + E+ Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEI-IFHKCEFVGEMAVVQQ 128 Query: 136 ----AEDSMYEVLEKALDKAMQLGEIQKG-NPKFAAHAFVSLLS 174 Y+ +E+ L ++ + + AA +S Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYIS 172
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 51.8 bits (124), Expect = 8e-09 Identities = 37/232 (15%), Positives = 85/232 (36%), Gaps = 25/232 (10%) Query: 203 LLVATVLLVLVLLILLYRSPILAILPLLVVGFAYGIISPTLGFLADHGWIKVDAQAISIM 262 L A +L+ LV+ + L ++ ++P + V + T LA G+ +I+ + Sbjct: 344 LFEAIMLVFLVMYLFL-QNMRATLIPTIAVPVV---LLGTFAILAAFGY------SINTL 393 Query: 263 T----VLLFGAGTDYCLFLISRYREYLLEEESKYK-ALQLAIKASGGAIIMSALTVVLGL 317 T VL G D + ++ ++E++ K A + ++ GA++ A+ + Sbjct: 394 TMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVF 453 Query: 318 GTLLL--AHYGAFHR-FAVPFSVAVFIMGIAALTILPAFLLIFGRTAFFPFIPRTTSMNE 374 + GA +R F++ A+ + + AL + PA + P + +E Sbjct: 454 IPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLK-------PVSAEHHE 506 Query: 375 ELARRKKKVVKVKKSKGAFSKKLGDVVVRRPWTIIMLTVFVLGGLASFVPRI 426 ++ +++ ++ G+ R+ Sbjct: 507 NKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRL 558 Score = 38.3 bits (89), Expect = 1e-04 Identities = 28/161 (17%), Positives = 68/161 (42%), Gaps = 9/161 (5%) Query: 203 LLVATVLLVLVLLILLYRSPILAILPLLVVGFAYGIISPTLGFLADHGWIKVDAQAISIM 262 L+ + ++V + L LY S + + +LVV I+ L + V + Sbjct: 875 LVAISFVVVFLCLAALYESWSIPVSVMLVVPLG--IVGVLLAATLFNQKNDVYFM---VG 929 Query: 263 TVLLFGAGTDYCLFLISRYREYLLEE-ESKYKALQLAIKASGGAIIMSALTVVLGLGTLL 321 + G + ++ ++ + +E + +A +A++ I+M++L +LG+ L Sbjct: 930 LLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLA 989 Query: 322 LAH---YGAFHRFAVPFSVAVFIMGIAALTILPAFLLIFGR 359 +++ GA + + + + A+ +P F ++ R Sbjct: 990 ISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 31.7 bits (72), Expect = 0.012 Identities = 32/202 (15%), Positives = 69/202 (34%), Gaps = 21/202 (10%) Query: 533 AGISNAEDQL--WIGGETASLYDTKQITERDEAVIIPVMISIIALLLLVYLRSIVAMIYL 590 A + N +L IG + + ++++ ++ + ++ L L S + + Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 591 IVTVVLSFFSALGAGWLLLHYGMGAPAIQGAIPLYAFVFLVALGEDYNIFMVSEIWKNRK 650 ++ V L L A L + + G + + L I +V + Sbjct: 901 MLVVPLGIVGVLLAAT-LFNQKNDVYFMVG------LLTTIGLSAKNAILIVEFAKDLME 953 Query: 651 TQNHLDAVKNGVIQTGSVITSAGLILAGTFAVLGTLPIQV------LVQFGIVTAI--GV 702 + V + + L+ + F +LG LP+ + Q + + G+ Sbjct: 954 KEGK--GVVEATLMAVRMRLRPILMTSLAF-ILGVLPLAISNGAGSGAQNAVGIGVMGGM 1010 Query: 703 LLDTFIVRPLLVPAITVVLGRF 724 + T + VP VV+ R Sbjct: 1011 VSATLLAI-FFVPVFFVVIRRC 1031
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 41.1 bits (96), Expect = 1e-06 Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 6/98 (6%) Query: 49 YSSVEMMRYSIEELDS--YKVIMDEKIIGGIIVTISGKSYGRIDRIFVEPVYQGKGIGSN 106 Y +M +EE + ++ IG I + + Y I+ I V Y+ KG+G+ Sbjct: 50 YEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTA 109 Query: 107 VIKL-IE--AEYPSIRIWDLETSSRQINNHHFYKKMGY 141 ++ IE E + LET I+ HFY K + Sbjct: 110 LLHKAIEWAKENHFCGLM-LETQDINISACHFYAKHHF 146
>PRPHPHLPASEC#Prokaryotic zinc-dependent phospholipase C signature. Length = 398 Score = 28.1 bits (62), Expect = 0.048 Identities = 13/72 (18%), Positives = 26/72 (36%), Gaps = 11/72 (15%) Query: 112 GILTIGGTGAICLGRKGEVYEYSGGW-GHILGDEGSGYWIALQGLKRMANQFDQGVTLCP 170 ++ ++ G +VY W G I G G+ I QG+ + N + Sbjct: 8 ALICATLATSLWAGASTKVY----AWDGKIDG-TGTHAMIVTQGVSILENDLSKNEP--- 59 Query: 171 LSLRIQDEFQLL 182 ++ ++L Sbjct: 60 --ESVRKNLEIL 69
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.9 bits (62), Expect = 0.027 Identities = 15/62 (24%), Positives = 28/62 (45%), Gaps = 6/62 (9%) Query: 84 VMLTLLAVIMGHIYPMLFKGKGGKGIS-----TFIGGLIAFDYLIALTLVAVFIIFYLIF 138 +++T LA I+G + P+ G G +GG+++ L + F++ F Sbjct: 974 ILMTSLAFILGVL-PLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCF 1032 Query: 139 KG 140 KG Sbjct: 1033 KG 1034
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 28.7 bits (64), Expect = 0.044 Identities = 10/52 (19%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Query: 15 ESIHKLNYKTFVEEIPQHEETKDRVRIDRFHEENT-YLICLDDDKLVGMVAL 65 + L +TF + + + D + D++ NT YL + D+ ++ + Sbjct: 18 GELFTLRKETFKDRLNWAVQCTDGMEFDQYDNNNTTYLFGIKDNTVICSLRF 69
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 30.3 bits (68), Expect = 0.013 Identities = 20/113 (17%), Positives = 39/113 (34%), Gaps = 6/113 (5%) Query: 338 AGGSGLAITFVAAKDEKH------LEEIEKTLGAPIQREIIEQPKIKRVDENGKPLPKPA 391 A +++T V D + E + + V E KP PKP Sbjct: 40 APAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPK 99 Query: 392 PKKSGEYRQRDSREGSRSGSKGRTRNDSRNSSRNENNRSFNKPSNKKGSTKQG 444 PK + +++ R+ S+ + ++ +R ++ + S S G Sbjct: 100 PKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASG 152
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 27.6 bits (61), Expect = 0.005 Identities = 8/23 (34%), Positives = 13/23 (56%) Query: 31 KINWYNDMKTSFANKELADLVKG 53 K+ Y+ +KT N++LA K Sbjct: 84 KLKNYDKVKTELLNEDLAKKYKD 106
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.4 bits (177), Expect = 8e-18 Identities = 30/174 (17%), Positives = 72/174 (41%), Gaps = 13/174 (7%) Query: 8 EERRKEILETAERLFLTKGYTKTTVNDILKEIGIAKGTFYHYFKSKEEVMDEIIMRIIKE 67 +E R+ IL+ A RLF +G + T++ +I K G+ +G Y +FK K ++ E I + + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE-IWELSES 68 Query: 68 DVAKAKVIVSNPNIPVLEKLFRVLME---QSPKSGDIKDKMIE-QFHQPNNA---EMYQK 120 ++ + ++ + R ++ +S + + + ++E FH+ + Q+ Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 121 SLVQSIIHLSPVLTEILEQGIEEGIFSTSY-PQETIELLLSSAQVIFDEGLFQW 173 + + + + L+ IE + + ++ + W Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGY----ISGLMENW 178
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 58/342 (16%), Positives = 125/342 (36%), Gaps = 36/342 (10%) Query: 49 IFAGLYAITSIPFLLAPLGGAIADRFNRRNLMVIFDFINTAIVLSFIVLLFTGSVSILLI 108 I LYA+ F AP+ GA++DRF RR +++ A+ + ++ + +L I Sbjct: 47 ILLALYALMQ--FACAPVLGALSDRFGRR-PVLLVSLAGAAV--DYAIMATAPFLWVLYI 101 Query: 109 GTIMFLLAIVNAMYAPVVMASIPQLVPEKKLEQANGIVNGVQALSNIVAPVLGGILYGII 168 G I +A + V A I + + + G ++ + PVLGG++ G Sbjct: 102 GRI---VAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLM-GGF 157 Query: 169 GLKMLVIISCLAFFLSAILEMFITIPFIKRVQESHIIPTIVKDMKGGFIYVLKQPFILKS 228 + L+ + F+ +P + + + + + Sbjct: 158 SPHAPFFAAAALNGLNFLTGCFL-LPESHKGERRPLRREALNPLASFRWARGMTVVAA-L 215 Query: 229 MLLAALLNLILTPLFVVGAPIIIRVTMESSH-TLYGIGMGLIDFATIIGALSMVFFAKKL 287 M + ++ L+ V A + + + H IG+ L F I+ +L+ + Sbjct: 216 MAVFFIMQLVGQ----VPAALWVIFGEDRFHWDATTIGISLAAFG-ILHSLAQAMITGPV 270 Query: 288 QMQTLYYWMILIALLVIPMALSVTPFILNLGY------YPPFILFILSSILIAMIMTVVS 341 + L++ M T +IL +P +L I + + ++S Sbjct: 271 AA-----RLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLS 325 Query: 342 IYVITVVQKKTPNENLGKVMAIITAVSQCMAPIGQVIYGFMF 383 V E G++ + A++ + +G +++ ++ Sbjct: 326 RQV--------DEERQGQLQGSLAALTSLTSIVGPLLFTAIY 359 Score = 29.0 bits (65), Expect = 0.033 Identities = 16/79 (20%), Positives = 34/79 (43%), Gaps = 3/79 (3%) Query: 88 TAIVLSFIVLLFTGSVSILLIGTIMFLLAIVNAMYAPVVMASIPQLVPEKKLEQANGIVN 147 A +I+L F + ++ + P + A + + V E++ Q G + Sbjct: 285 IADGTGYILLAFATRGWMAFPIMVLLASG---GIGMPALQAMLSRQVDEERQGQLQGSLA 341 Query: 148 GVQALSNIVAPVLGGILYG 166 + +L++IV P+L +Y Sbjct: 342 ALTSLTSIVGPLLFTAIYA 360
>SECA#SecA protein signature. Length = 901 Score = 27.1 bits (60), Expect = 0.035 Identities = 9/24 (37%), Positives = 14/24 (58%) Query: 33 ESQPTQKESRFLDTWRWQNYFLLH 56 E Q E++ L + +QNYF L+ Sbjct: 361 EGVQIQNENQTLASITFQNYFRLY 384
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 386 bits (992), Expect = e-138 Identities = 99/262 (37%), Positives = 147/262 (56%), Gaps = 3/262 (1%) Query: 39 HKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQ 97 H + ++ E + R+G+ +D + +T+ A+R +ERF ST+K + G +L + Sbjct: 20 HASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLAR 79 Query: 98 NSTKK--LDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIG 155 L+ I Y ++DLVDYSPV+EKH+ GMT+GE+ AA+ SDN+A N+L +G Sbjct: 80 VDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVG 139 Query: 156 GPKGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHK 215 GP G LRQ+GD VT DR+ETELNEA+PGD RDT+T ++A L+ L Sbjct: 140 GPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARS 199 Query: 216 RNILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILS 275 + L +WM + LIR+ +P W +ADK+GAG G R +A++ P N+A I+ I Sbjct: 200 QRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYL 259 Query: 276 SKDEKGATYDNQLIAEAAEVIV 297 NQ IA ++ Sbjct: 260 RDTPASMAERNQQIAGIGAALI 281
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.9 bits (93), Expect = 2e-05 Identities = 72/361 (19%), Positives = 140/361 (38%), Gaps = 58/361 (16%) Query: 60 TIYGITVSASSWFSGVFVQMWGPRKVMTFGLVSFILGS-IGFIGIGIQHMNYPVILICYA 118 T + +T S + G G ++++ FG++ GS IGF+G H + ++++ Sbjct: 56 TAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVG----HSFFSLLIMARF 111 Query: 119 LRGFGYPLFAYSFLVWVSYSTPQQ-------------------------MLSRAVGWFWF 153 ++G G F +V V+ P++ M++ + W + Sbjct: 112 IQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYL 171 Query: 154 VFQLGLSVIGAFYSSYMVPKIGEI--------ATLWSALIFVVVGGLFSIVVNKDKFKAQ 205 + +++I + ++ K I L S I + LF+ + Sbjct: 172 LLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFM--LFTTSYSISFLIVS 229 Query: 206 TVSANKSSELLKGITIAFENPKVG------IGGIVKIINSAAQFGFVVFLPTYMMKYNFT 259 +S + ++ +T F +P +G IG + I GFV +P YMMK Sbjct: 230 VLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVP-YMMKDVHQ 288 Query: 260 MTEWLQIWGTLFFVNMVFNIIFGIVG----DKFGWINTIKWFGGVGCGIVTLALYYVPQM 315 ++ +I + F + IIFG +G D+ G + + +G ++++ + Sbjct: 289 LSTA-EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLN----IGVTFLSVSFLTASFL 343 Query: 316 VGHNYWAILF-VACCYGATLAGYVPLTALVP-SLSPENKGAAMSVLNLGSGLSAFVGPLV 373 + W + + G ++ +V SL + GA MS+LN S LS G + Sbjct: 344 LETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403 Query: 374 V 374 V Sbjct: 404 V 404
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 30.4 bits (68), Expect = 0.012 Identities = 37/201 (18%), Positives = 67/201 (33%), Gaps = 24/201 (11%) Query: 187 AARLAELAEEAGLPKGVLNIVNGAHDVVNGLLEHKLVKAISFVGSQPVAEYVYKKGTENL 246 + L E+A+ AG+ +G + L + S +G EY K + L Sbjct: 31 STSLGEIAKAAGVTRGAIYWHFKDKS---DLFSEIWELSESNIGELE-LEYQAKFPGDPL 86 Query: 247 KRVQALAGAKNHSIVLNDANLELATKQIISAAFGSAGERCMAASVVTVEEEIADQLVERL 306 ++ + S V + +II GE A V + + + +R+ Sbjct: 87 SVLREILIHVLESTVTEER--RRLLMEIIFHKCEFVGEM---AVVQQAQRNLCLESYDRI 141 Query: 307 VAEANKIVIGNGLDEDVFLGPVIRDNHKERTI--GYIDSGVEQGA------TLVRDGRED 358 + L D+ + I GYI +E L ++ R+ Sbjct: 142 EQTLKHCIEAKMLPADL-------MTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDY 194 Query: 359 TAVKGAGYFVGPTIFDHVTKE 379 A+ Y + PT+ + T E Sbjct: 195 VAILLEMYLLCPTLRNPATNE 215
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.0 bits (158), Expect = 3e-15 Identities = 30/151 (19%), Positives = 66/151 (43%), Gaps = 8/151 (5%) Query: 1 MEKSREQTMENILKAAKKKFGERGYEGTSIQEIAKEAKVNVAMASYYFNGKENLYYEVFK 60 ++ ++T ++IL A + F ++G TS+ EIAK A V ++F K +L+ E+++ Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 K-YGLANELPNFLEKNQF-NPINALREYLTVFTTHIKENPE-----IGTLAYEEIIKESA 113 EL + +P++ LRE L E + E A Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 114 RLEK-IKPYFIGSFEQLKEILQEGEKQGVFH 143 +++ + + S++++++ L+ + + Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLP 155
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.9 bits (77), Expect = 0.002 Identities = 11/34 (32%), Positives = 19/34 (55%) Query: 338 IVLDGKNGSGKSSILKLILGQSIQYTGLVTLGTG 371 +VL+G G GKS+++ ++G +GTG Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTG 632
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.4 bits (63), Expect = 0.011 Identities = 25/105 (23%), Positives = 38/105 (36%), Gaps = 6/105 (5%) Query: 41 EQQLEKYIESENTLAFKVIDEETKEVIGHISLGQIDHINKSARIGKVLVGDTRMRGRSIG 100 + Y+E E AF E IG I + + N A I + V R + +G Sbjct: 53 DDMDVSYVEEEGKAAFLYYLEN--NCIGRIKIRS--NWNGYALIEDIAV-AKDYRKKGVG 107 Query: 101 KHMMKAVLHIAFDELKLHRVTLGVYDFNTSAISCYEKIGFVKEGL 145 ++ + A E + L D N SA Y K F+ + Sbjct: 108 TALLHKAIEWA-KENHFCGLMLETQDINISACHFYAKHHFIIGAV 151
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 9e-24 Identities = 40/150 (26%), Positives = 74/150 (49%), Gaps = 3/150 (2%) Query: 5 ILIIDDDKEIVELLAVYLRNEGYNIYKAYDGDEALQMISTYEVDLMILDIMMPKRNGLEV 64 IL+ DDD I +L L GY++ + + I+ + DL++ D++MP N ++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 65 CQEVRE-NNTVPILMLSAKAEDMDKILGLMTGADDYMIKPFNPLELVARV-KALLRRSSF 122 +++ +P+L++SA+ M I GA DY+ KPF+ EL+ + +AL Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 123 QNASSPKNEDGM-IRIRSAEIHKHNHTVKV 151 + ++DGM + RSA + + + Sbjct: 126 PSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 41.9 bits (98), Expect = 7e-07 Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 8/91 (8%) Query: 186 DMDYIEKTNHTFYGAYVDNDLKGSICI----NEQGKISFIFIDKEYRNRGIGSKLLQVAR 241 D+ Y+E+ + Y++N+ G I I N I I + K+YR +G+G+ LL A Sbjct: 56 DVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAI 115 Query: 242 D---ELNLESLLISFPNNSLLE-GFVKKTGF 268 + E + L++ + ++ F K F Sbjct: 116 EWAKENHFCGLMLETQDINISACHFYAKHHF 146 Score = 39.2 bits (91), Expect = 5e-06 Identities = 18/52 (34%), Positives = 22/52 (42%) Query: 83 LAVHPNYRGVGVSQKLFELHKEEALQNECKQLFLEVIVGNDRAIRFYNKLGY 134 +AV +YR GV L E A +N L LE N A FY K + Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.6 bits (95), Expect = 8e-06 Identities = 66/351 (18%), Positives = 119/351 (33%), Gaps = 27/351 (7%) Query: 40 LPWIAYQLTGSAVIMSS---LFAINVLPIVLFGPLVGVIIDRYDRKKLLLVADITNIILV 96 LP + L S + + L A+ L P++G + DR+ R+ +LLV+ + Sbjct: 28 LPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDY 87 Query: 97 SFVPILHSLHLLEIWHLYIITFMLAVMSMLFDVTTVTVIPKIAGASLTKANSFYQMVNQL 156 + + L W LYI + + V + G + F Sbjct: 88 AIMATAPFL-----WVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGF 142 Query: 157 ASLFGPMIAGVFISFIGGFQLLWINVLSFIATLVAVMLLPSMKTTNKKCEDKNTLQNVLS 216 + GP++ G+ F L+ + L LLP + L+ Sbjct: 143 GMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGE-----RRPLRREAL 197 Query: 217 DLVNGFTWLKNDRLNLALSFQAMIGNFGASAVLGVFMYYLLSTLQLTPEQSGVNYSLIGI 276 + + F W + + AL I +++ + G++ + GI Sbjct: 198 NPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGI 257 Query: 277 -GGLLGSLIAIPLEKRLQRSILIPLLLFVGAIGLTFALWNT-YWFA-PGI----AFGVAM 329 L ++I P+ RL + L + G + T W A P + + G+ M Sbjct: 258 LHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM 317 Query: 330 TCNIAWNTIVATVRQETVPSNMQGRVLGFSRVLTRLAMPLGALVGGIISAY 380 A +++ V QG++ G LT L +G L+ I A Sbjct: 318 P---ALQAMLSR----QVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 26.3 bits (58), Expect = 0.025 Identities = 8/33 (24%), Positives = 17/33 (51%) Query: 37 QNNNLNYKVEVDRELAINHAINMASSNDIVLIA 69 + +K+EVD+E A ++++ N + A Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTA 752
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.8 bits (163), Expect = 6e-15 Identities = 27/112 (24%), Positives = 54/112 (48%), Gaps = 1/112 (0%) Query: 3 KIMIVEDDMKIAELLSTHVAKYGYEGIIVSDFQNVLNIFLEEQPELVLLDINLPSFDGYY 62 I++ +DD I +L+ +++ GY+ I S+ + +LV+ D+ +P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 WCRQIRGV-STCPILFISAREGTMDQVMALENGGDDFISKPFHYEVVMAKIR 113 +I+ P+L +SA+ M + A E G D++ KPF ++ I Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 28.7 bits (64), Expect = 0.012 Identities = 10/50 (20%), Positives = 17/50 (34%), Gaps = 12/50 (24%) Query: 6 WFRHLP-QISMDLSEWTPFIQNNWHRKHYMKFVYVLQIIIFLIPYYFGAD 54 W + P ++ D Q + + + LI Y FGA+ Sbjct: 91 WKQKDPKDVTQDTLAIIDKYQAEFGTQK-----------VILIGYSFGAE 129
>PF06580#Sensor histidine kinase Length = 349 Score = 37.9 bits (88), Expect = 7e-05 Identities = 17/102 (16%), Positives = 37/102 (36%), Gaps = 18/102 (17%) Query: 388 QVFI-NILQNSIEAMPDGGRISIHIKEIGKDGIIISVIDKGIGIPAERIKRLGEPFYSTK 446 Q + N +++ I +P GG+I + + + + V + G Sbjct: 261 QTLVENGIKHGIAQLPQGGKILLKGTKDNGT-VTLEVENT------------GSLALKNT 307 Query: 447 EKGTGIGLMLSYKIIESHQGN---ISIMSEVGVGTTVTIYLP 485 ++ TG GL + ++ G I + + G + +P Sbjct: 308 KESTGTGLQNVRERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>PF06580#Sensor histidine kinase Length = 349 Score = 36.0 bits (83), Expect = 2e-04 Identities = 18/94 (19%), Positives = 39/94 (41%), Gaps = 12/94 (12%) Query: 320 NLIKNGIEAMPNGGTLNISSSISNNKVIIRIEDSGIGMSQEQVNRFGEPYFNTKTKGTGL 379 N IK+GI +P GG + + + N V + +E++G + ++ GTGL Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT----------KESTGTGL 315 Query: 380 G-TMVAVKIIETMQGSLRIRSVVNKGTTLTITFP 412 ++++ + +++ K + P Sbjct: 316 QNVRERLQMLYGTEAQIKLSEKQGKVNA-MVLIP 348
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.8 bits (106), Expect = 4e-07 Identities = 64/318 (20%), Positives = 119/318 (37%), Gaps = 24/318 (7%) Query: 13 LLLSGVGIANLGAWIYLIALNVLVYHMGGSALAVATLYVIKPLAAL---FTNAWSGSMID 69 ++LS V + +G + + L L+ + S A ++ L AL G++ D Sbjct: 9 VILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSD 68 Query: 70 RLNKRKLMIHLDIYRAVCIAILPLLPSLWMVYVFVFFISMANAIYEPTAMTYMTKLIPVE 129 R +R +++ AV AI+ P LW++Y+ + A A Y+ + + Sbjct: 69 RFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYIADITDGD 127 Query: 130 QRQRFNSLRSLIGSGASVIGPAIAGALLIASTPE---FAIYMNAIAFLLSGVITLLLPNL 186 +R R S V GP + G + S A +N + FL LLP Sbjct: 128 ERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTG---CFLLPES 184 Query: 187 DKKFDSHTSNDTLSLAVLKKDWNIVLNFSKKSLYIVFVYFLFQGMMVLAAANDSLELSFA 246 K L L + + + +F M ++ +L + F Sbjct: 185 HK-----GERRPLRREALNPLASFRWARGMTVVA--ALMAVFFIMQLVGQVPAALWVIFG 237 Query: 247 KEVLLLTDSEYGFLVSIAGAGFILGAITNAI----LSKKLTPSLLIGIGSLFIAIGYIIY 302 ++ + G S+A G IL ++ A+ ++ +L + +G + GYI+ Sbjct: 238 EDRFHWDATTIGI--SLAAFG-ILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILL 294 Query: 303 AFSNEFLIAAIGFFILSF 320 AF+ +A +L+ Sbjct: 295 AFATRGWMAFPIMVLLAS 312 Score = 29.0 bits (65), Expect = 0.032 Identities = 21/115 (18%), Positives = 48/115 (41%), Gaps = 1/115 (0%) Query: 48 TLYVIKPLAALFTNAWSGSMIDRLNKRKLMIHLDIYRAVCIAILPLLPSLWMVYVFVFFI 107 +L L +L +G + RL +R+ ++ I +L WM + + + Sbjct: 251 SLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLL 310 Query: 108 SMANAIYEPTAMTYMTKLIPVEQRQRFNSLRSLIGSGASVIGPAIAGALLIASTP 162 + + I P +++ + E++ + + + S S++GP + A+ AS Sbjct: 311 A-SGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASIT 364
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.5 bits (71), Expect = 0.001 Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Query: 81 IWHIAVHPDFRRMKIGNQLLNEGEKLAKERKLNRLEAWTRD-NLWVHGWYEKNGFV--KV 137 I IAV D+R+ +G LL++ + AKE L T+D N+ +Y K+ F+ V Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAV 151 Query: 138 DSYLH 142 D+ L+ Sbjct: 152 DTMLY 156
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 34.0 bits (78), Expect = 9e-04 Identities = 12/50 (24%), Positives = 18/50 (36%) Query: 81 YAAGIADLRTKKQMKTDFRFRIGSTTKTFIATVLLQLAGENRLNLDDSIE 130 +A RT + D RF + ST K + +L L+ I Sbjct: 43 IEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIH 92
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.1 bits (65), Expect = 0.011 Identities = 18/104 (17%), Positives = 40/104 (38%), Gaps = 4/104 (3%) Query: 151 EGQYVQAFYNQTASAHLWNSENMKLYLGFYKDEVVSVGSLVCTLDSIG-IYDIATKEEMR 209 Y + + + E +L + ++ + + + I DIA ++ R Sbjct: 43 SKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYR 102 Query: 210 GKGFGSTMFNYLLQEAKELNVAQCVLQASPDGV---NIYKKAGF 250 KG G+ + + ++ AKE + +L+ + + Y K F Sbjct: 103 KKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 27.6 bits (61), Expect = 0.013 Identities = 25/123 (20%), Positives = 37/123 (30%), Gaps = 16/123 (13%) Query: 30 AKVYIKPDGDA---VEYQP------FAIYNGDLMVGFVMHAVVKETTDMYWINGFIIDQK 80 +K Y K D V Y F Y + +G + + I + + Sbjct: 43 SKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRI--KIRSNWNGYALIEDIAVAKD 100 Query: 81 QQGNGYGKAALQESIYLIKNTFKACKEIRLTVHKDNISAKKLYESYGFQPLGHD---YDG 137 + G G A L ++I K + L NISA Y + F D Y Sbjct: 101 YRKKGVGTALLHKAIEWAKE--NHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSN 158 Query: 138 EEV 140 Sbjct: 159 FPT 161
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 47.1 bits (112), Expect = 6e-08 Identities = 38/186 (20%), Positives = 79/186 (42%), Gaps = 8/186 (4%) Query: 206 MMGTKQVYLLFFMLFTSCMGGLYLIGMVKDIGVQLVGLSTATAANAVAMIAIFNTVGRI- 264 M + + ++ + +G + LI V ++ + S A+ ++A++ + Sbjct: 1 MKPNRPLIVILSTVALDAVG-IGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFAC 59 Query: 265 --VLGTLSDKIGRMKIVSATFIIIGLSVFTLSFIPLNYGIYFACVASFAFCFGGNITIFP 322 VLG LSD+ GR ++ + + ++ P + +Y + A G + Sbjct: 60 APVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRI--VAGITGATGAVAG 117 Query: 323 AIVGDFFGLKNHSTNYGIVYQGFGFGALAGSFIGAILGGFQP--TFIIIGVLSVISFIIS 380 A + D + ++G + FGFG +AG +G ++GGF P F L+ ++F+ Sbjct: 118 AYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTG 177 Query: 381 ILIRPP 386 + P Sbjct: 178 CFLLPE 183 Score = 37.9 bits (88), Expect = 6e-05 Identities = 27/146 (18%), Positives = 58/146 (39%), Gaps = 13/146 (8%) Query: 8 PLLIVLGTIIVQIGLGTIYTWSLFNQPLVSKFGWNLNSVAITFS-ITSFSLSFSTLFAGK 66 L+ + I+ +G W +F + +F W+ ++ I+ + + G Sbjct: 213 AALMAVFFIMQLVGQVPAALWVIFGE---DRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 67 LQQKLGLRKLIATAGIVLGLGLILSSQVSS----LPLLYLLAGVVVGYADGTAYITSLSN 122 + +LG R+ + I G G IL + + P++ LLA +G A ++ + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVD 329 Query: 123 LIKWFPNRKGLISGISVSAYGMGSLI 148 R+G + G + + S++ Sbjct: 330 -----EERQGQLQGSLAALTSLTSIV 350
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 34.0 bits (78), Expect = 2e-04 Identities = 13/49 (26%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Query: 64 LIRNEEKEIVGRINLVDIDTETRISSLGYRVGEKF----TKKGVATAAV 108 I+ E ++ GR+ ++++D + + +R E+F T K V AV Sbjct: 28 QIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAV 76
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 32.4 bits (73), Expect = 0.023 Identities = 28/136 (20%), Positives = 54/136 (39%), Gaps = 19/136 (13%) Query: 611 VARGYLGKSKLTDEKFVPSPFAAGEMMYHTGDLVRWLPNGELEYLGRMDHQVKIRGYRIE 670 ++R YL ++ +DE+F M + D+ L + L DH+V RG +++ Sbjct: 428 LSRDYLSTNEPSDEEF------KNAMSVYINDIAEGLSS-----LPETDHRVVYRGLKLD 476 Query: 671 LREIETQLREYPEINQVIV--------VDQVYGNRKLLAAYYVSDNKVSFGEIRKYLSDK 722 + L+EY I +I+ D+ + N +L Y +K + + Sbjct: 477 KPALSDVLKEYTTIGNIIIDKAFMSTSPDKAWINDTILNIYLEKGHKGRILGDVAHFKGE 536 Query: 723 LPEFMIPEKMIQVEEI 738 P +++E I Sbjct: 537 AEMLFPPNTKLKIESI 552
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 310 bits (795), Expect = e-101 Identities = 187/588 (31%), Positives = 267/588 (45%), Gaps = 67/588 (11%) Query: 1 MKNKKTLTKVALTTGLALTAVAPYGVGHAEETDQLQVQIQEESFRSGELTQPSQKAPENV 60 M + L + L GL P+G ++ Q + SF SG L + Sbjct: 1 MNKRAMLGAIGLAFGLM---AWPFGASAKGKSMVWNEQWKTPSFVSGSLLGRCSQ----- 52 Query: 61 VKDALKEKTEQALSPKQVNGETGVDYKVLQKRGSYDGTTLVRIQQTYEGKEVYGHQLTAH 120 + + +Q + Q+ G+ ++ + G T++R +Q G L AH Sbjct: 53 --ELVYRYLDQEKNTFQLGGQARERLSLIGNKLDELGHTVMRFEQAIAASLCMGAVLVAH 110 Query: 121 VDNSGVIKSVSGDSAQNLKQEELKKPINLSKDEATQYIYTKYGNDI---NFISEPEVKEV 177 V++ + S+SG NL + LK +S +A + + +E Sbjct: 111 VNDGE-LSSLSGTLIPNLDKRTLKTEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTR 169 Query: 178 IFVDENNGQASNAYQVTFEAATPNYISGTYLINAQNGDMLK--NMVQESNLKASEKLVGA 235 + + + AY+V TP + Y+I+A +G +L N + E+ ++ + G Sbjct: 170 LVIYPDEETPRLAYEVNVRFLTPVPGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAG- 228 Query: 236 LKKSKKSSLTSLTGTGKDDLGISRSFGISKQSN-GKYALADYTRGQGIETYDVNYRDITK 294 TS G G+ LG + + S G Y L D TRG GI TYD R Sbjct: 229 ---------TSTVGVGRGVLGDQKYINTTYSSYYGYYYLQDNTRGSGIFTYDGRNR---- 275 Query: 295 EESYYPGTLATSTSTTF---NDPKAVSAHYLATKVFDFYKDKYNRNSFDNQGQKVVSVVH 351 + PG+L F D AV AHY A V+D+YK+ + R S+D + S VH Sbjct: 276 --TVLPGSLWADGDNQFFASYDAAAVDAHYYAGVVYDYYKNVHGRLSYDGSNAAIRSTVH 333 Query: 352 AWDSGDTNDPKNWQNALSANNGSMLVYGD-------PIVKAYDVAGHEFTHAVTSSESNL 404 + + NA NGS +VYGD P DV GHE THAVT + L Sbjct: 334 Y--------GRGYNNA--FWNGSQMVYGDGDGQTFLPFSGGIDVVGHELTHAVTDYTAGL 383 Query: 405 EYYGESGAINEALSDIMGTSIEKYVNNGSFNWTMGEQT------GSVFRDMENPTSVPSS 458 Y ESGAINEA+SDI GT +E Y N + +W +GE G R M +P Sbjct: 384 VYQNESGAINEAMSDIFGTLVEFY-ANRNPDWEIGEDIYTPGVAGDALRSMSDPAKYGD- 441 Query: 459 LGVPYPDDYSEFNDFNGWDQGGVHFNSSIINKVAYLIAKGGTHNGVTVKGIGEDKMFDIF 518 PD YS+ D GGVH NS IINK AYL+++GG H GV+V GIG DKM IF Sbjct: 442 -----PDHYSKRYTGTQ-DNGGVHTNSGIINKAAYLLSQGGVHYGVSVTGIGRDKMGKIF 495 Query: 519 YYANTDELNMTSNFKELRSACIRVATNKYGANSAEVQAVQKAFDAAKI 566 Y A L TSNF +LR+AC++ A + YG+ S EV +V++AF+A + Sbjct: 496 YRALVYYLTPTSNFSQLRAACVQAAADLYGSTSQEVNSVKQAFNAVGV 543
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 443 bits (1141), Expect = e-156 Identities = 180/445 (40%), Positives = 270/445 (60%), Gaps = 22/445 (4%) Query: 1 MFRTISNFMRVAEIRRKILFTLAMLIVFRIGTFIPVPHTNAEVLK-----IQDQANVLGM 55 M + R ++R+K+LFTLA+++V+R+GT IP+P + + ++ + G+ Sbjct: 1 MLTAFARAFRTPDLRKKLLFTLAIIVVYRVGTHIPIPGVDYKNVQQCVREASGNQGLFGL 60 Query: 56 LNVFGGGALQHFSIFAVGITPYITASIIVQLLQMDVIPKFSEWAKQGEMGRKKSAQFTRY 115 +N+F GGAL +IFA+GI PYITASII+QLL + VIP+ K+G+ G K Q+TRY Sbjct: 61 VNMFSGGALLQITIFALGIMPYITASIILQLLTV-VIPRLEALKKEGQAGTAKITQYTRY 119 Query: 116 FTIILAFIQAIGMSYGFNNI-------AGGQLITDQSWTTYLFIATVLTAGTAFLLWLGE 168 T+ LA +Q G+ + GGQ++ DQS T + + +TAGT ++WLGE Sbjct: 120 LTVALAILQGTGLVATARSAPLFGRCSVGGQIVPDQSIFTTITMVICMTAGTCVVMWLGE 179 Query: 169 QITANGVGNGISMLIFAGLVAAIPNVANQIYLQQFQNAGDQLFMHIIKMLLIGLVILAIV 228 IT G+GNG+S+L+F + A P+ I Q G F +I V L +V Sbjct: 180 LITDRGIGNGMSILMFISIAATFPSALWAIKKQGTLAGGWIEFGTVI------AVGLIMV 233 Query: 229 VGVIYIQQAVRKIPIQYAKAVSGNNQYQGAKNTHLPLKVNSAGVIPVIFASAFLMTPRTI 288 V++++QA R+IP+QYAK + G Y G +T++PLKVN AGVIPVIFAS+ L P + Sbjct: 234 ALVVFVEQAQRRIPVQYAKRMIGRRSY-GGTSTYIPLKVNQAGVIPVIFASSLLYIPALV 292 Query: 289 AQLFPDSSVSKWLVAN--LDFAHPIGMTLYVGLIVAFTYFYAFIQVNPEQMAENLKKQNG 346 AQ +S K V HPI + Y LIV F +FY I NPE++A+N+KK G Sbjct: 293 AQFAGGNSGWKSWVEQNLTKGDHPIYIVTYFLLIVFFAFFYVAISFNPEEVADNMKKYGG 352 Query: 347 YVPCIRPGKSTEQYVTKILYRLTFIGAIFLGAISILPLVFTKIATLPPSAQIGGTSLLII 406 ++P IR G+ T +Y++ +L R+T+ G+++LG I+++P + + GGTS+LII Sbjct: 353 FIPGIRAGRPTAEYLSYVLNRITWPGSLYLGLIALVPTMALVGFGASQNFPFGGTSILII 412 Query: 407 VGVALETMKTLESQLVKRHYKGFIK 431 VGV LET+K +ESQL +R+Y+GF++ Sbjct: 413 VGVGLETVKQIESQLQQRNYEGFLR 437
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 59.3 bits (143), Expect = 4e-13 Identities = 34/196 (17%), Positives = 74/196 (37%), Gaps = 11/196 (5%) Query: 12 RSLETKKKLLHSGYTIFIRNGFQKTTITQIIKHAETGYGTAYVYFKNKDDLLIVLMEDVM 71 + ET++ +L +F + G T++ +I K A G Y +FK+K DL + ++ Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW-ELS 66 Query: 72 NQFYNIAERSFSPQTTEEARTMIQNQVKAFLQLAEKE------RAILQVVEEAIGLSKEI 125 E + + + ++++ + L+ E I+ E +G + Sbjct: 67 ESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVV 126 Query: 126 RQKWDEIRERFINSITQDITYSQESGLAHSKLNKEIVARAWFAMNEMFLWTIVQNDKKLE 185 +Q + + I Q + + E+ + + L A + + + + Sbjct: 127 QQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFD 186 Query: 186 LEEI----VHTLTEMY 197 L++ V L EMY Sbjct: 187 LKKEARDYVAILLEMY 202
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 386 bits (994), Expect = e-131 Identities = 119/343 (34%), Positives = 188/343 (54%), Gaps = 32/343 (9%) Query: 304 TFPGVIGTSDAFQHTLEEIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAV 363 ++G S A Q + + TD ++ + GE+G GKE VARA+H+ R+NGPF+A+ Sbjct: 135 DGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194 Query: 364 NCGALPKELMESELFGYAEGAFTGARRQGYKGKFEQADGGTIFLDEIGEVPPEMQVALLR 423 N A+P++L+ESELFG+ +GAFTGA+ + G+FEQA+GGT+FLDEIG++P + Q LLR Sbjct: 195 NMAAIPRDLIESELFGHEKGAFTGAQTRS-TGRFEQAEGGTLFLDEIGDMPMDAQTRLLR 253 Query: 424 VLQERTVTPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSLIER 483 VLQ+ T +G + ++RI+ AT+KDL + + +G FR+DLYYRL+V PL +P L +R Sbjct: 254 VLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDR 313 Query: 484 KEDIPYFIKHFCKRKNWNVVFPKSI----CNQFSQHTWPGNIRELLNALERIYILSQGRE 539 EDIP ++HF ++ + K H WPGN+REL N + R+ L Sbjct: 314 AEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDV 373 Query: 540 ICEKQISFLLQTMMRNQHQLELQTENKTEDTLN--------------------------F 573 I + I L++ + +E +++ Sbjct: 374 ITREIIENELRSEI-PDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRV 432 Query: 574 REKIQRDSMIEALEKTNGNVSSAAKLLDVPRSTFYKRMQKYKL 616 +++ ++ AL T GN AA LL + R+T K++++ + Sbjct: 433 LAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.2 bits (104), Expect = 4e-08 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 4/94 (4%) Query: 65 EESKNLFLVAEVHDRIVGFSRCEGSNLKRLSHKIEFGVCILKEFWGYGIGKSLLGQSIHW 124 EE K FL + + +G + SN + + V K++ G+G +LL ++I W Sbjct: 62 EEGKAAFL-YYLENNCIGRIKIR-SNWNGYALIEDIAVA--KDYRKKGVGTALLHKAIEW 117 Query: 125 ADENEIKKISLQVLETNEKAIQLYKKLGFEVEGI 158 A EN + L+ + N A Y K F + + Sbjct: 118 AKENHFCGLMLETQDINISACHFYAKHHFIIGAV 151
>PF06580#Sensor histidine kinase Length = 349 Score = 35.6 bits (82), Expect = 3e-04 Identities = 33/173 (19%), Positives = 60/173 (34%), Gaps = 38/173 (21%) Query: 282 IIKQSDHISNLIEEL---LRFS---KLERDVLQKEEFSIKSLVQSILDKHKIELESKEIN 335 I++ ++ L +R+S R V +E + +V S L I+ E + Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELT---VVDSYLQLASIQFEDR--- 239 Query: 336 LQVNYNVGDAIVYADVNKMRMVFQNLISNAIKY-----TSNQNIKITLEDRNESVYFQIQ 390 LQ + AI+ V M + Q L+ N IK+ I + N +V +++ Sbjct: 240 LQFENQINPAIMDVQVPPM--LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVE 297 Query: 391 NGMNAEHMKDIDKIWEPFYVLESSRSKDRSGTGLGLAIVKS-IVERHGFDYGV 442 N + TG GL V+ + +G + + Sbjct: 298 N--TGSLALK----------------NTKESTGTGLQNVRERLQMLYGTEAQI 332
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 30.9 bits (69), Expect = 0.004 Identities = 14/53 (26%), Positives = 20/53 (37%), Gaps = 5/53 (9%) Query: 12 LELTGISYGQLYRWKRKNLIPEDWFVRKSTFTGQETFFPKEKILERINKIQTM 64 L+ + G KNL P D R T G +K+L KI ++ Sbjct: 97 LDKADAALGPA-----KNLAPLDVINRSLTIVGNALQQKNQKLLLNQKKITSL 144
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 80.3 bits (198), Expect = 1e-18 Identities = 53/318 (16%), Positives = 113/318 (35%), Gaps = 9/318 (2%) Query: 50 LIFGLQPFSDIVFTLIAGGITDKYGRKKIMLLGLLLQGVAIGSFVFAQSVFIFALLYVIN 109 ++ L + G ++D++GR+ ++L+ L V A +++ + ++ Sbjct: 47 ILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVA 106 Query: 110 GIGRSLYIPAQRAQIADLIKQGQQAEIFALLQTMGAIGTVIGPLIGAVFYNTHPEYLFIM 169 GI + A IAD+ ++A F + G V GP++G + P F Sbjct: 107 GITGAT-GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFA 165 Query: 170 QSITLMVYAVVVWTQLPETAPAITMPKQKLEVSSPKQF--VRNHSAVIGLMVSTLPISFF 227 + + + LPE+ P ++ ++ F R + V LM + Sbjct: 166 AAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLV 225 Query: 228 YAQTETNYRIFAEDVFPNFIFILAFISTCRAIMEIILQIFLV-KWSERFSMAKIIIISYT 286 + IF ED F + I+ + Q + + R + +++ Sbjct: 226 GQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLG-- 283 Query: 287 CYIVAAIGYGFSATIVS--LFFTLLFLVIGESIALNHLLRFVSEIAPSDKRGLYFSIYGL 344 I GY A + F ++ L+ I + L +S +++G Sbjct: 284 -MIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAA 342 Query: 345 HWDVSRTCGPVIGAILLS 362 ++ GP++ + + Sbjct: 343 LTSLTSIVGPLLFTAIYA 360 Score = 47.5 bits (113), Expect = 5e-08 Identities = 20/121 (16%), Positives = 53/121 (43%), Gaps = 1/121 (0%) Query: 45 IMITMLIFGLQPFSDIVFTLIAGGITDKYGRKKIMLLGLLLQGVAIGSFVFAQSVFIFAL 104 I + + + +I G + + G ++ ++LG++ G FA ++ Sbjct: 246 TTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFP 305 Query: 105 LYVINGIGRSLYIPAQRAQIADLIKQGQQAEIFALLQTMGAIGTVIGPLIGAVFYNTHPE 164 + V+ G + +PA +A ++ + + +Q ++ L + ++ +++GPL+ Y Sbjct: 306 IMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASIT 364 Query: 165 Y 165 Sbjct: 365 T 365
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 29.3 bits (65), Expect = 0.014 Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 20/130 (15%) Query: 20 LAACKGTDEKKETNP----TSENSKNEQNTSSEGK-----KEPEVKSNTDSNSKDIVINQ 70 L A KG+ + NP EN N GK K + KS+ +++ KD++INQ Sbjct: 719 LKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVIINQ 778 Query: 71 KSINHVKNLFELAKEGKVPNVPFAAHTGDIEEIEKAWGKADKTEQAGNGMYATFTNKNVS 130 K + V NL + K TGD +E+A + A KN S Sbjct: 779 KVTDKVDNLNQAVSVAKA--------TGDFSRVEQALADLKNFSKE---QLAQQAQKNES 827 Query: 131 FGFNKGSQVF 140 K S+++ Sbjct: 828 LNARKKSEIY 837
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 35.4 bits (81), Expect = 9e-06 Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 3/49 (6%) Query: 6 IVGGILGWLASLITGRDVPGGVIG-NIIAGIIGSWIGGKLLGSFGPVIG 53 V ++ L SL+ G G+ G I+ GI+ S+I L + V+G Sbjct: 475 GVSYVVALLFSLLAG--TTLGIWGIAIVTGILCSYIDKNKLNTINEVLG 521
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.8 bits (106), Expect = 4e-07 Identities = 65/342 (19%), Positives = 118/342 (34%), Gaps = 11/342 (3%) Query: 1 MWRNKNVWIVLIGEFIAGLGLWLGILGNLEFMQKYVPSDFMKS---VILFIGLLAGVLVG 57 M N+ + ++L + +G+ L + ++ V S+ + + ++L + L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 58 PMAGRIIDQYEKKKVHLYAGFGRVISVIFMFFAIQFESIAFMIAFMVALQISAAFYFPAL 117 P+ G + D++ ++ V L + G + M A + I +VA A Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVL--YIGRIVAGITGATGAVAG- 117 Query: 118 QSVIPLIVREHELLQMNGVHMNVGTIARIAGTSLGGILLVVMSLQYMYAFSMAAYALLFL 177 + I I E + G +AG LGG L+ S + + A L FL Sbjct: 118 -AYIADITDGDERARHFGFMSACFGFGMVAGPVLGG-LMGGFSPHAPFFAAAALNGLNFL 175 Query: 178 STFFLQFEDKKSTTPSKQAAKDNSFMEVFRILRGIPIAFTALILSIIPLLFIAGFNLMVI 237 + FL E K + N +A + I+ L+ L VI Sbjct: 176 TGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVI 235 Query: 238 -NISEMQHDPTIKGFIYTIEGIAFMLG-AFVIKRLSDHFKPEKLLYFFAVCTAFAHLSLF 295 D T G GI L A + ++ + L + ++ L Sbjct: 236 FGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLA 295 Query: 296 FSDIKWMSLTSFGLFGFSVGCFFPIMSTIFQTKVEKSYHGRL 337 F+ WM+ L G P + + +V++ G+L Sbjct: 296 FATRGWMAFPIMVLLAS-GGIGMPALQAMLSRQVDEERQGQL 336
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 35.5 bits (82), Expect = 2e-04 Identities = 28/135 (20%), Positives = 45/135 (33%), Gaps = 42/135 (31%) Query: 1 MKILILGGTRFLGRAFVEEALQRGHEV-----------TLFNRGTNQEI------FLE-- 41 MK L+ G F+G + L+ GH+V + + + F + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 42 ------VEQLIGDRNGDV-----------SSLENRKWDVVINTCGFSPHHIRNVGEVLKD 84 + L + + SLEN N GF N+ E + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFL-----NILEGCRH 115 Query: 85 -NIEHYIFISSLSVY 98 I+H ++ SS SVY Sbjct: 116 NKIQHLLYASSSSVY 130
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 2e-05 Identities = 16/71 (22%), Positives = 29/71 (40%) Query: 60 LSQTHKEEAYVHFIGVNPKYRRRGIASTLYSYFFDVARANKRKVVKAITSPVNKKSIQFH 119 + A + I V YR++G+ + L + A+ N + T +N + F+ Sbjct: 82 IRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFY 141 Query: 120 REIGFRIEAGD 130 + F I A D Sbjct: 142 AKHHFIIGAVD 152
>PF06580#Sensor histidine kinase Length = 349 Score = 29.4 bits (66), Expect = 0.017 Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 7/78 (8%) Query: 250 IQRLFDNIFQNVLKHSKAK---KLKIIIDEDIVYF--RDNGIGFDINSK-GTGLGLKNI- 302 +Q L +N ++ + LK D V + G N+K TG GL+N+ Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVR 319 Query: 303 EDISKMFDIKYTLQSNSE 320 E + ++ + ++ + + Sbjct: 320 ERLQMLYGTEAQIKLSEK 337
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.9 bits (184), Expect = 8e-18 Identities = 36/117 (30%), Positives = 61/117 (52%), Gaps = 3/117 (2%) Query: 6 ILIVEDDLIIGDLLQKILQREKYNVYWEKEGRKVLDII--HEIDLVVMDVMLPGEDGYQI 63 IL+ +DD I +L + L R Y+V + I + DLVV DV++P E+ + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 TKKIKNLGLNIPIIFLSARNDMDSKLKGLTIGE-EYMIKPFDPRELLLRIQKMLGNQ 119 +IK ++P++ +SA+N + +K G +Y+ KPFD EL+ I + L Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 29.7 bits (66), Expect = 0.030 Identities = 48/195 (24%), Positives = 87/195 (44%), Gaps = 35/195 (17%) Query: 174 TRESKRINNIMVLIK--IGMILLFITVGIFYVKPMNWIPIAPYGLSGVFTGGAAILFAFT 231 TR+++ N IM I +G +L ++V ++ VFTGGA++ A Sbjct: 304 TRKAEETNRIMGCIGKVLGALLTIVSV-----------------VAAVFTGGASLALAAV 346 Query: 232 GFDILATSAEEVKDPKRNLPIGIIASLIICTIIYVMVCLVMTGMVSYKE-LNVPEAMAYV 290 G ++ E VK I + I+ ++ ++ L+ + E L V + A Sbjct: 347 GLAVMVAD-EIVKAATGVSFIQQALNPIMEHVLKPLMELIGKAITKALEGLGVDKKTA-- 403 Query: 291 MEVVGQ--GKVAGAIAVGAVIGLMAVIFSNMYAATRVFFAMSRDGLLPKSFAKVNKKTGA 348 E+ G G + AIA+ AVI ++AV+ AA ++ A+S+ ++ ++ K+ Sbjct: 404 -EMAGSIVGAIVAAIAMVAVIVVVAVVGKG--AAAKLGNALSK--MMGETIKKL-----V 453 Query: 349 PTFITGLAGIGSSII 363 P + LA GS + Sbjct: 454 PNVLKQLAQNGSKLF 468
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.8 bits (119), Expect = 7e-09 Identities = 20/123 (16%), Positives = 54/123 (43%), Gaps = 8/123 (6%) Query: 5 IVDDEKAVRSMLAQIIEDEDLGEVIGEAENGLSLEQQMLILKN--IDILFIDLLMPIQDG 62 + DD+ A+R++L Q + +V + + + D++ D++MP ++ Sbjct: 8 VADDDAAIRTVLNQALSRAGY-DVRITS----NAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 63 IKTIRQIKPSFKG-KIIMVSQVESKELIAEAYSLGVEYYIIKPINRIEVLTVVRKVIERI 121 + +IK + ++++S + +A G Y+ KP + E++ ++ + + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 122 RLE 124 + Sbjct: 123 KRR 125
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.0 bits (78), Expect = 0.001 Identities = 61/379 (16%), Positives = 127/379 (33%), Gaps = 42/379 (11%) Query: 45 WGAILGYFGYGYMIGSLLGGIFSDKKGPKFVWIVAATAWSIFEIATAFAGEIGIAVFGGS 104 +G +L + + + G SD+ G + V +V+ ++ A A + + G Sbjct: 45 YGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIG-- 102 Query: 105 ALIGFAIFRVLFGLTEGPSFAVSNKTAANWAAPKERAFLTSLGFVGVPLGAVLTA-PVAV 163 R++ G+T G + AV+ A+ ERA GF+ G + A PV Sbjct: 103 --------RIVAGIT-GATGAVAGAYIADITDGDERA--RHFGFMSACFGFGMVAGPVLG 151 Query: 164 LLLSFTSWKIMFFILGTIGIVWAIIWYFTFTNMPEDHPRVTKEELAEIRSTEGVLQSAKV 223 L+ S FF + + + F +PE H + E + + Sbjct: 152 GLMGGFSPHAPFFAAAALNGLNFLTGCFL---LPESHKGERRPLRREALNPLASFR---- 204 Query: 224 EKEIPKEPWYSFFKVPTFVMVTIAYFCFQYINFLILTWTPKYLQDVFHFQLSSLWYLGMI 283 W V +M +F Q + + + +D FH+ ++ +G+ Sbjct: 205 --------WARGMTVVAALMAV--FFIMQLVGQVPAALWVIFGEDRFHWDATT---IGIS 251 Query: 284 PWLGACITLPLGAKLSDRILRKTGNLRLARTGLPIIALLLTAICFSFIPAMNNYVAVLAL 343 + A ++ + + G R G ++ + + + Sbjct: 252 LAAFGILHSLAQAMITGPVAARLGERRALMLG-----MIADGTGYILLAFATRGWMAFPI 306 Query: 344 MSLGNAFAFLPSSLFWAIIVDTAPAYSGTYSGIMHFIANIATILAPTLTGYL---VVSYG 400 M L + +L + G G + + ++ +I+ P L + ++ Sbjct: 307 MVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTW 366 Query: 401 YPSMFIVAAILAAIAMGAM 419 +I A L + + A+ Sbjct: 367 NGWAWIAGAALYLLCLPAL 385 Score = 29.0 bits (65), Expect = 0.037 Identities = 28/161 (17%), Positives = 45/161 (27%), Gaps = 12/161 (7%) Query: 290 ITLPLGAKLSDRILRKTGNLRLARTGLPIIALLLTAICFSFIPAMNNYVAVLALMSLGNA 349 P+ LSDR R+ ++ L A I A ++ VL + + Sbjct: 58 ACAPVLGALSDRFGRR----------PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAG 107 Query: 350 FAFLPSSLFWAIIVDTAPAYSGT-YSGIMHFIANIATILAPTLTGYLVVSYGYPSMFIVA 408 ++ A I D + G M + P L G + + + F A Sbjct: 108 ITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG-GFSPHAPFFAA 166 Query: 409 AILAAIAMGAMLFVKPGQQTKTESLFNWRGKKRLEEPRANF 449 A L + F+ P L R Sbjct: 167 AALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWAR 207
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 749 bits (1935), Expect = 0.0 Identities = 417/885 (47%), Positives = 578/885 (65%), Gaps = 18/885 (2%) Query: 93 YTLAELNKMPNSELIDTLSKISWNQITDLFQFNQDTKAFYQNKERMNVIINELGQRGRTF 152 YT ELN+M S+L++ + IS+ + DLF FN + F+ N++R+ II L GRT+ Sbjct: 93 YTFDELNRMNYSDLVELIKTISYENVPDLFNFNDGSYTFFSNRDRVQAIIYGLEDSGRTY 152 Query: 153 TKENSKGIETFVEVLRSAFYVGYYNNELSYLKERSFHEKCLPALKAIAKNPNFTLGTAEQ 212 T ++ KGI T VE LR+ +Y+G+YN +LSYL +CLPA+KAI N NF LGT Q Sbjct: 153 TADDDKGIPTLVEFLRAGYYLGFYNKQLSYLNTPQLKNECLPAMKAIQYNSNFRLGTKAQ 212 Query: 213 DRVVAAYGKLIGNASSDTETVQYAVNVLKQYNDNLTTYVSDYAKGQAVYEIVKGIDYDIQ 272 D VV A G+LIGNAS+D E + + VL + DN+ Y S+Y+KG AV+ ++KGIDY Sbjct: 213 DGVVEALGRLIGNASADPEVINNCIYVLSDFKDNIDKYGSNYSKGNAVFNLMKGIDYYTN 272 Query: 273 SYLQDT-NKQPNETMWYGKIDNFINEVNRIALVGN-ITNENSWLINNGIYYAGRLGKFHS 330 S + +T T +Y +ID ++ + + +G+ + N+N+WL+NN +YY GR+GKF Sbjct: 273 SVIYNTKGYDAKNTEFYNRIDPYMERLESLCTIGDKLNNDNAWLVNNALYYTGRMGKFRE 332 Query: 331 NPYKGLEVITQAMSLYPRLSGPYFVAVEQIKTNYGGKDYSGKAVDLQKIREEGKRQYLPK 390 +P + +AM YP LS Y A + N+GGK+ SG +D KI+ + + +YLPK Sbjct: 333 DPSISQRALERAMKEYPYLSYQYIEAANDLDLNFGGKNSSGNDIDFNKIKADAREKYLPK 392 Query: 391 TYTFDDGSIVFKTGDKVTEEKIKRLYWAAKEVKAQYHRVIGNDKALEPGNADDVLTIVIY 450 TYTFDDG V K GDKVTEEKIKRLYWA+KEVKAQ+ RV+ NDKALE GN DD+LT+VIY Sbjct: 393 TYTFDDGKFVVKAGDKVTEEKIKRLYWASKEVKAQFMRVVQNDKALEEGNPDDILTVVIY 452 Query: 451 NNPDEYQLNRQLYGYETNNGGIYIEEKRTFFTYERTPKQSIYSLEELFRHEFTHYLQGRY 510 N+P+EY+LNR + G+ T+NGGIYIE TFFTYERTP++SIY+LEELFRHEFTHYLQGRY Sbjct: 453 NSPEEYKLNRIINGFSTDNGGIYIENIGTFFTYERTPEESIYTLEELFRHEFTHYLQGRY 512 Query: 511 EVPGLFGSGEMYQNERLTWFQEGNAEFFAGSTRTNNVVPRKSMISGLSSDPASRYTAKQT 570 VPG++G GE YQ LTW++EG AEFFAGSTRT+ + PRKS+ GL+ D +R + Sbjct: 513 VVPGMWGQGEFYQEGVLTWYEEGTAEFFAGSTRTDGIKPRKSVTQGLAYDRNNRMSLYGV 572 Query: 571 LFSKYGSWDFYKYSFALQSYLYNHQFDTFDKLQDLIRVNDVKNYDSYRESLSNNTQLNAE 630 L +KYGSWDFY Y FAL +Y+YN+ F+K+ + I+ NDV Y Y S+S++ LN + Sbjct: 573 LHAKYGSWDFYNYGFALSNYMYNNNMGMFNKMTNYIKNNDVSGYKDYIASMSSDYGLNDK 632 Query: 631 YQAYMQQLIDNQDKYNVPQVTNDYLIQHAPKPLAEVKNEIVDVANIKDAKITKYESQFFN 690 YQ YM L++N D +VP V+++Y+ H K + E+ N+I +V+NIKD +SQFF Sbjct: 633 YQDYMDSLLNNIDNLDVPLVSDEYVNGHEAKDINEITNDIKEVSNIKDLSSNVEKSQFFT 692 Query: 691 TFTVEGKYTGGTSKGESEDWKTMSKQVNRTLEQLSQKGWSGYKTVTAYFVNYRVNAANQF 750 T+ + G Y GG S+GE DWK M+ ++N L++LS+K W+GYKTVTAYFVN++V+ + Sbjct: 693 TYDMRGTYVGGRSQGEENDWKDMNSKLNDILKELSKKSWNGYKTVTAYFVNHKVDGNGNY 752 Query: 751 EYDIVFHGVATE--EKEKTNTIVN--MNGPYSGIVNEEIQFHSDGTKSENGKVTSYLWNF 806 YD+VFHG+ T+ N + S IV EEI F +K E+G++ +Y W+F Sbjct: 753 VYDVVFHGMNTDTNTDVHVNKEPKAVIKSDSSVIVEEEINFDGTESKDEDGEIKAYEWDF 812 Query: 807 GDGTTSTEANPTHVYEEKGTYTVELTVKDRRGKESKEQTKVTVKQD----------PQTG 856 GDG S EA TH Y + G Y V+LTV D G + E K+ V +D P Sbjct: 813 GDGEKSNEAKATHKYNKTGEYEVKLTVTDNNGGINTESKKIKVVEDKPVEVINESEPNND 872 Query: 857 EFHEEEKVLLFNTLVKGNLVTPDQTDVYTFDVTDTKEVDISVVNEQNIGMTWVLYHESDM 916 F + ++ N LVKG L D +D Y FDV V I++ N ++G+TW LY E D+ Sbjct: 873 -FEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKGNVKITLNNLNSVGITWTLYKEGDL 931 Query: 917 QNYVA-CGEDEGNVIKGKFEAKPGKYYLNVYKFDDKNGEYSLLVK 960 NYV ++G V+KG+ +PG+YYL+VY +D+++G Y++ VK Sbjct: 932 NNYVLYATGNDGTVLKGEKTLEPGRYYLSVYTYDNQSGTYTVNVK 976 Score = 89.8 bits (222), Expect = 2e-20 Identities = 102/514 (19%), Positives = 173/514 (33%), Gaps = 90/514 (17%) Query: 488 KQSIYSLEELF--RHEFTHYLQGRYEVPGLFGSGEMYQNERLTWFQEGNAEFFAGSTRTN 545 K I S+ + ++ Y+ + A+ Sbjct: 617 KDYIASMSSDYGLNDKYQDYMDSLLNNIDNLD----VPLVSDEYVNGHEAKDIN---EIT 669 Query: 546 NVVPRKSMISGLSSDPASRYTAKQTLFSKYGSWDFYKYSFALQSYLYNH-QFDTFDKLQD 604 N + S I LSS K F+ Y D +S + D KL D Sbjct: 670 NDIKEVSNIKDLSS-----NVEKSQFFTTY---DMRGTYVGGRSQGEENDWKDMNSKLND 721 Query: 605 LIRVNDVKNYDSYRESL----------SNNTQLNAEYQAYMQQLIDNQDKYNVPQ--VTN 652 +++ K+++ Y+ + N + + + P+ + + Sbjct: 722 ILKELSKKSWNGYKTVTAYFVNHKVDGNGNYVYDVVFHGMNTDTNTDVHVNKEPKAVIKS 781 Query: 653 DYLIQHAPKPLAEVKNEI-VDVANIKDA--KITKYESQFFNTFTVEGKYTGGTSKGESED 709 D + V+ EI D KD +I YE F + G E++ Sbjct: 782 DSSVI--------VEEEINFDGTESKDEDGEIKAYEWDFGD----------GEKSNEAKA 823 Query: 710 WKTMSKQVNRTLEQLSQKGWSGYKTVTAYFVNYRVNAANQFEYDIVFHGVATEEKEKTNT 769 +K ++ G T + ++ +++ + EK N Sbjct: 824 THKYNKTGEYEVKLTVTDNNGGINTESK-----KIKVVEDKPVEVINESEPNNDFEKANQ 878 Query: 770 IVNMNGPYSGIVNEE---IQFHSDGTKSENGKVTS----------YLWNFGDGTT-STEA 815 I N G ++EE +++ D K N K+T L+ GD A Sbjct: 879 IAKSNMLVKGTLSEEDYSDKYYFDVAKKGNVKITLNNLNSVGITWTLYKEGDLNNYVLYA 938 Query: 816 NPTHVYEEKGTYTVE-------------------LTVKDRRGKESKEQTKVTVKQDPQTG 856 KG T+E + VK E KE K +K+ Sbjct: 939 TGNDGTVLKGEKTLEPGRYYLSVYTYDNQSGTYTVNVKGNLKNEVKETAKDAIKEVENNN 998 Query: 857 EFHEEEKVLLFNTLVKGNLVTPDQTDVYTFDVTDTKEVDISVVNEQNIGMTWVLYHESDM 916 +F + KV N+ + G L D D+Y+ D+ + +++I V N NI M W+LY D+ Sbjct: 999 DFDKAMKVDS-NSKIVGTLSNDDLKDIYSIDIQNPSDLNIVVENLDNIKMNWLLYSADDL 1057 Query: 917 QNYVACGEDEGNVIKGKFEAKPGKYYLNVYKFDD 950 NYV +GN + + PGKYYL VY+F++ Sbjct: 1058 SNYVDYANADGNKLSNTCKLNPGKYYLCVYQFEN 1091
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 8e-04 Identities = 36/152 (23%), Positives = 69/152 (45%), Gaps = 3/152 (1%) Query: 42 ISNEIGLSNSSAGLIVTLTQIGYVVGLLFLVPLGDIVENKKLILILLFLSAFA-LISMVF 100 I+N+ +S + T + + +G L D + K+L+L + ++ F +I V Sbjct: 40 IANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVG 99 Query: 101 VKSATLLLIASFFIGLGSVAAQVLVP-LVSYLSSENARGRVVGNVMSGLLLGIMLARPIS 159 +LL++A F G G+ A LV +V+ + RG+ G + S + +G + I Sbjct: 100 HSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIG 159 Query: 160 SLVADMWGWNAIFALSATVIIVLAFVLSKVLP 191 ++A W+ + L + I+ L K+L Sbjct: 160 GMIAHYIHWSYLL-LIPMITIITVPFLMKLLK 190
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 85.8 bits (212), Expect = 4e-23 Identities = 26/170 (15%), Positives = 58/170 (34%), Gaps = 12/170 (7%) Query: 4 KRGRPRNIETQKAILSASYELLLESGFKAVTVDKIADRAKVSKATIYKWWPNKAAVV--- 60 ++ + ET++ IL + L + G + ++ +IA A V++ IY + +K+ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 61 ---MDGFLSAAAARLPVPDTGS---ALNDILTHATSLANFLISREGTIINELVGEGQFDS 114 + + G L +IL H R + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 115 --KLAEEYRARYFQPRRLQAKQLLEKGMKRGELKENLDVELSIDLIYGPI 162 + + R + +Q L+ ++ L +L + ++ G I Sbjct: 123 MAVVQQAQRNLCLESYDR-IEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>cloacin#Cloacin signature. Length = 551 Score = 32.8 bits (74), Expect = 0.003 Identities = 23/88 (26%), Positives = 29/88 (32%), Gaps = 6/88 (6%) Query: 327 GNNGRGSQGNNGHQQENNGRGSQGNNGNQQGNNGRGSQGNNGHQQENNGRGSQGNNGNQQ 386 G +GRG N G G ++G +G ENN G +G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDG------SGWSSENNPWGGGSGSGIHW 56 Query: 387 GDNGRGSQQGNNGNQQGDNGRGSQKENV 414 G G NGN G +G G V Sbjct: 57 GGGSGHGNGGGNGNSGGGSGTGGNLSAV 84 Score = 29.7 bits (66), Expect = 0.026 Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 2/73 (2%) Query: 296 NNGRESQQGN--NGNQQGNNGRESQQGNNGNQQGNNGRGSQGNNGHQQENNGRGSQGNNG 353 N G S GN G G + G+ + + N G G+ H +G G+ G NG Sbjct: 10 NTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Query: 354 NQQGNNGRGSQGN 366 N G +G G + Sbjct: 70 NSGGGSGTGGNLS 82
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 71.2 bits (174), Expect = 2e-17 Identities = 28/172 (16%), Positives = 68/172 (39%), Gaps = 3/172 (1%) Query: 8 KEKIIETSLYLFNTNGITRTSIQDIMTATELPKGSIYRRFKNKEEIVLAAYDKSGEIMWS 67 ++ I++ +L LF+ G++ TS+ +I A + +G+IY FK+K ++ ++ S + Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 68 HFHKAMENK-KTAIDKILAIFLVYQDAANNPPI-AGGCPLLNSAIESTGVFPELQKAAAK 125 + + + I + ++ ++ E G +Q+A Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRN 132 Query: 126 GYDDTVMLMASLIKEGIEKQELKEEINIISLASFLASSMEGAIMASRVSNDN 177 ++ + +K IE + L ++ A + + G M + + Sbjct: 133 LCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL-MENWLFAPQ 183
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 37.0 bits (86), Expect = 1e-04 Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 8/56 (14%) Query: 356 TVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAY 411 T+N + A G + VG++ADLVLW+ P +GV + V G IA Sbjct: 410 TINPAIAHGLSHEIGSLEVGKRADLVLWN-------PAFFGVK-PDMVLLGGTIAA 457
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.010 Identities = 21/121 (17%), Positives = 42/121 (34%), Gaps = 28/121 (23%) Query: 3 YVISLQGPMASGKTTLAKKLELHGLSVIYENPYPIVEKR---KQL---------NLD-MN 49 Y + L+G GK+TL L GL + + I + +Q+ + Sbjct: 597 YSVVLEGTGGIGKSTLINT--LVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFR 654 Query: 50 SKEGFIANQKMFIEAKIKEFQNAKGSVVIFDRGPEDIEFYTIFYPTTIGKEWDIETELKD 109 + K F ++ ++ A + R +D + + TT +++ L D Sbjct: 655 RAD--AEAVKAFFSSRKDRYRGA------YGRYVQDHPRQVVIWCTTNKRQY-----LFD 701 Query: 110 E 110 Sbjct: 702 I 702
>CHLAMIDIAOM6#Chlamydia cysteine-rich outer membrane protein 6 signature. Length = 547 Score = 28.5 bits (63), Expect = 0.002 Identities = 11/27 (40%), Positives = 15/27 (55%) Query: 12 YTIVVQNTGTLPAQNVTFTDPLPAGTT 38 Y I + N GT A+NV +P+P G Sbjct: 229 YKINIVNQGTATARNVVVENPVPDGYA 255 Score = 27.7 bits (61), Expect = 0.003 Identities = 11/27 (40%), Positives = 13/27 (48%) Query: 12 YTIVVQNTGTLPAQNVTFTDPLPAGTT 38 Y I V N G L ++V D L G T Sbjct: 335 YVISVSNPGDLVLRDVVVEDTLSPGVT 361
>CHLAMIDIAOM6#Chlamydia cysteine-rich outer membrane protein 6 signature. Length = 547 Score = 47.4 bits (112), Expect = 6e-07 Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 26/163 (15%) Query: 787 VTYTITFTNQGTIPATNVTITDALPPGTSFVTNSVTVNNVTQPGASPVTGILVGTVNPGE 846 V Y I NQGT A NV + + +P G + V +G + PGE Sbjct: 227 VVYKINIVNQGTATARNVVVENPVPDGYA------------HSSGQRVLTFTLGDMQPGE 274 Query: 847 TVTVTFQIQINAIPPSGKIENTASVTYTSQPNPNEPPITTTETTPTVTIPVRTANLNPQK 906 T+T + G+ N A+V+Y + N +TT P V + + A Sbjct: 275 HRTITVEF---CPLKRGRATNIATVSYCGG-HKNTASVTTVINEPCVQVSIAGA------ 324 Query: 907 TVDREFASIGDTLTYTITLQNTGNIPATNVIITDSIPTGTTFI 949 +++ + + Y I++ N G++ +V++ D++ G T + Sbjct: 325 ----DWSYVCKPVEYVISVSNPGDLVLRDVVVEDTLSPGVTVL 363 Score = 36.2 bits (83), Expect = 0.001 Identities = 42/176 (23%), Positives = 65/176 (36%), Gaps = 26/176 (14%) Query: 1698 KTATPETVTLGDIITYTISLQNTGTIPANNILVSDPIPTGTSFIQNSVTINNVSQPTANP 1757 K PE L + Y I++ N GT A N++V +P+P G + + Sbjct: 214 KQEGPENACLRCPVVYKINIVNQGTATARNVVVENPVPDG------------YAHSSGQR 261 Query: 1758 ETGIQIPTLSPSESATISFHVLVTSIPPSGEIQNQGNVSFQYQPDATKPPVSVTTPTPTT 1817 + + P E TI+ G N VS+ K SVTT Sbjct: 262 VLTFTLGDMQPGEHRTITVEFCPLK---RGRATNIATVSY---CGGHKNTASVTTVINEP 315 Query: 1818 ITPVNVGTINPIKTADKSIVSVGDTITFTITFQNEGTIPVTDISVTDSLPAGTSFI 1873 V+ I AD S V + + I+ N G + + D+ V D+L G + + Sbjct: 316 CVQVS------IAGADWSYVC--KPVEYVISVSNPGDLVLRDVVVEDTLSPGVTVL 363 Score = 36.2 bits (83), Expect = 0.001 Identities = 37/163 (22%), Positives = 65/163 (39%), Gaps = 26/163 (15%) Query: 127 ITYTITFNNDGTVPATNVIFTDSIPAGTTFIPNSVVLNNNPVPNSNPALGITVGTLNPGE 186 + Y I N GT A NV+ + +P G + L T+G + PGE Sbjct: 227 VVYKINIVNQGTATARNVVVENPVPDGYAH------------SSGQRVLTFTLGDMQPGE 274 Query: 187 TKTLSFQVRVTQIPAGGTITNEASTTYTYQPDPTLPPVTTTEPTPPTSVTVNTATVNPTK 246 +T++ + + G TN A+ +Y T VTT P V++ A Sbjct: 275 HRTITVEFCPLK---RGRATNIATVSYCGGHKNT-ASVTTVINEPCVQVSIAGAD----- 325 Query: 247 SADRAFADIGDIITYTISLQNNGTVPATNIILTDPIPNGTTFI 289 ++ + + Y IS+ N G + ++++ D + G T + Sbjct: 326 -----WSYVCKPVEYVISVSNPGDLVLRDVVVEDTLSPGVTVL 363 Score = 35.1 bits (80), Expect = 0.004 Identities = 48/221 (21%), Positives = 80/221 (36%), Gaps = 40/221 (18%) Query: 1315 ITYTISLQNTGTVPATNVLVTDPIPAGTTFIPNSVTINDVTQPGIVPSSGILIGTLEPNT 1374 + Y I++ N GT A NV+V +P+P G + +G ++P Sbjct: 227 VVYKINIVNQGTATARNVVVENPVPDGYAHSSGQRVLT------------FTLGDMQPGE 274 Query: 1375 SAVVTFQVQVTSIPPTGFIENQGTVSFQYQPDPTRPPVSVTTPTPTTKTQVSEVTINPNK 1434 +T + G N TVS+ T + T ++E + + Sbjct: 275 HRTITVEFCPLK---RGRATNIATVSY----------CGGHKNTASVTTVINEPCVQVSI 321 Query: 1435 QGNPQTINLGDTVTYTITFQNVGNINATDVIITDPTPAGTTFIPNSVTINGVSSPGANPN 1494 G + + V Y I+ N G++ DV++ D G T + + GA + Sbjct: 322 AGADWSY-VCKPVEYVISVSNPGDLVLRDVVVEDTLSPGVTVL---------EAAGAQIS 371 Query: 1495 SGVNVGTV---TPGQIVTLTYQVTVTALPPDGIIKNTATVT 1532 V TV PG+ +L Y+V V A P N + Sbjct: 372 CNKVVWTVKELNPGE--SLQYKVLVRAQTPGQFTNNVVVKS 410 Score = 33.9 bits (77), Expect = 0.009 Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 28/164 (17%) Query: 523 VTFTVTFQNKGTVPATNVTVQDSLPQGVSFVPGSVVINGISQLGENPEIGIPIGTVNPGQ 582 V + + N+GT A NV V++ +P G + G V+ +G + PG+ Sbjct: 227 VVYKINIVNQGTATARNVVVENPVPDGYAHSSGQRVLT------------FTLGDMQPGE 274 Query: 583 SITVTFQGIVNSIPPG-GVIRNKANITFTYEPSPNEPPVTTTITTPETETTVNTATLEPQ 641 T+T V P G N A +++ N VTT I P + ++ A Sbjct: 275 HRTIT----VEFCPLKRGRATNIATVSYC-GGHKNTASVTTVINEPCVQVSIAGA----- 324 Query: 642 KTVNRSFVTLNDIITYTLSFQNVGTVSATNVTITDSIPAGTTFI 685 + S+V + Y +S N G + +V + D++ G T + Sbjct: 325 ---DWSYVC--KPVEYVISVSNPGDLVLRDVVVEDTLSPGVTVL 363 Score = 32.7 bits (74), Expect = 0.016 Identities = 36/166 (21%), Positives = 63/166 (37%), Gaps = 32/166 (19%) Query: 259 ITYTISLQNNGTVPATNIILTDPIPNGTTFIPNSVTINGISQPNTNPSTGITVGTLDPTE 318 + Y I++ N GT A N+++ +P+P +G + + T+G + P E Sbjct: 227 VVYKINIVNQGTATARNVVVENPVP------------DGYAHSSGQRVLTFTLGDMQPGE 274 Query: 319 AATISFQVQVISVPPHGLVENQGTVSFTHIVNPNEPPVTKTSPTPKTETAVNTIISTPTK 378 TI+ + G N TVS+ K +V T+I+ P Sbjct: 275 HRTITVE---FCPLKRGRATNIATVSYCG--------------GHKNTASVTTVINEPCV 317 Query: 379 TADKQLAD---IGDTITYTITFRNGGTVPATNVTLIDSTPSGTTFI 421 AD + + Y I+ N G + +V + D+ G T + Sbjct: 318 QVSIAGADWSYVCKPVEYVISVSNPGDLVLRDVVVEDTLSPGVTVL 363 Score = 32.0 bits (72), Expect = 0.029 Identities = 40/174 (22%), Positives = 66/174 (37%), Gaps = 26/174 (14%) Query: 1434 KQGNPQTINLGDTVTYTITFQNVGNINATDVIITDPTPAGTTFIPNSVTINGVSSPGANP 1493 KQ P+ L V Y I N G A +V++ +P P +G + Sbjct: 214 KQEGPENACLRCPVVYKINIVNQGTATARNVVVENPVP------------DGYAHSSGQR 261 Query: 1494 NSGVNVGTVTPGQIVTLTYQVTVTALPPDGIIKNTATVTYTFQPNPGEPPITITDPTPTV 1553 +G + PG+ T+T + G N ATV+Y + +T P V Sbjct: 262 VLTFTLGDMQPGEHRTITVEFCPLK---RGRATNIATVSYC-GGHKNTASVTTVINEPCV 317 Query: 1554 EVSVITPTPNPNKLADKQIVDINEIITYTVTFQNRGSVPATSVIVTDPLANGLT 1607 +VS+ A + + + Y ++ N G + V+V D L+ G+T Sbjct: 318 QVSI----------AGADWSYVCKPVEYVISVSNPGDLVLRDVVVEDTLSPGVT 361
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.0 bits (85), Expect = 1e-04 Identities = 32/234 (13%), Positives = 77/234 (32%), Gaps = 9/234 (3%) Query: 15 DGETTGLQNALKDVNKRSNDLTKELKDVERLLKFDPGNIEALAQKQQLLTQQIENTTQKL 74 E + + L+ +K ++ +++++E +E + +I+ + Sbjct: 91 TEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEK 150 Query: 75 DKLKAAEQQVQAQFQNGKISEEQYRAFRREIEFTEGSLNGLKNKLGNMKAEQDSVASSTR 134 L A + ++ + A + +E + +L + +L + +++ Sbjct: 151 AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 210 Query: 135 QLETLFSATGKSVDDFAGALGNRLVNAIRSGTATSKQLDQAIGIIGREALGTEADIEKLQ 194 A + A L A+ S I + E EA +L+ Sbjct: 211 AKIKTLEAEKAA----LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELE 266 Query: 195 RALRSV-----DAGNTIQQVQNELRDLQQEAGKTEKKFEGLKIGLENVIGGLAA 243 +AL I+ ++ E L+ E E + + L +++ L A Sbjct: 267 KALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDA 320
>PF07675#Cleaved Adhesin Length = 1358 Score = 26.2 bits (57), Expect = 0.024 Identities = 17/58 (29%), Positives = 23/58 (39%), Gaps = 3/58 (5%) Query: 23 HYSVADSYESNDAERVMYLQDEGFLNKERIIEKQEGSKGPVHVGGGYYE---LPNGEK 77 HY+V S NDA E L + ++ E +G G Y + LP G K Sbjct: 1172 HYAVYASSTGNDASNFANALLEEVLTAKTVVTAPEAIRGTRAQGTWYQKTVQLPAGTK 1229
>PF05043#Transcriptional activator Length = 493 Score = 29.9 bits (67), Expect = 0.020 Identities = 18/99 (18%), Positives = 34/99 (34%), Gaps = 11/99 (11%) Query: 196 AIKNSAVVKWILKFKSVLKQEDIDS------QVKNFVNNYLNISNDGGAASSDPRYDLEQ 249 I+N + W L + L ++++ + Q N + N+ NI SD + +L Sbjct: 308 EIENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPK---FVSDVKKELSH 364 Query: 250 VKPEAFVPDSKQMQETVQRIYNFFNTNEKIIQSKYNEDE 288 V S M Y F + ++ + Sbjct: 365 YLETLEVCSSSMM--VNHLSYTFITHTKHLVINLLQNQP 401
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 28.6 bits (64), Expect = 0.003 Identities = 12/30 (40%), Positives = 18/30 (60%), Gaps = 2/30 (6%) Query: 27 DEVLTTPEVMDVLGISKARISKMIKDGKLV 56 D V+T ++D GI KA I +KDG++ Sbjct: 69 DTVITNALILDHWGIVKADIG--LKDGRIA 96
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 32.2 bits (73), Expect = 5e-04 Identities = 9/50 (18%), Positives = 18/50 (36%), Gaps = 3/50 (6%) Query: 1 MQDLIKQYNTTLRQLREAQKDAKEEDVKVLTDMISDITYSLE---WMKKA 47 +Q L+ Y + + A+E D+ + +E WM + Sbjct: 101 VQALVNDYKQISSESKFVIGLAEENQDNATADLFVGLIEEVEKQVWMLSS 150
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 27.9 bits (62), Expect = 0.003 Identities = 7/21 (33%), Positives = 12/21 (57%) Query: 1 MITFVGVLLTIKFTREESRRE 21 MIT + V +K ++E R + Sbjct: 176 MITIITVPFLMKLLKKEVRIK 196
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 32.8 bits (75), Expect = 0.003 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 20/83 (24%) Query: 17 IVATDLLVQDGKIAKV--AEN---------ITADNAEVIDVNGKLIAPGLVDVHVHLREP 65 IV D+ ++DG+IA + A N I EVI GK++ G +D H+H P Sbjct: 83 IVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFICP 142 Query: 66 GGEHKETIETGTLAAAKGGFTTI 88 + IE A G T + Sbjct: 143 -----QQIEE----ALMSGLTCM 156
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 29.0 bits (65), Expect = 0.013 Identities = 10/41 (24%), Positives = 23/41 (56%) Query: 29 KMQFTGVQMANGIAEGIKTQYSVVRDALQETVSGAVNSIRS 69 +++ G +A G+ G + + +ALQE ++G V+++ Sbjct: 233 EIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMV 273
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 29.0 bits (65), Expect = 0.004 Identities = 12/58 (20%), Positives = 21/58 (36%), Gaps = 1/58 (1%) Query: 10 RKFYDKYNRDKEAKKFYDSTAWRRCRELALIRDNYRCQECMKHDPLIPVPADMVHHIK 67 R + K D+E +F+++ +R E K +PA + IK Sbjct: 100 RDYLIK-YSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIK 156
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 228 bits (583), Expect = 5e-80 Identities = 88/155 (56%), Positives = 115/155 (74%) Query: 4 IAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLDLIREATKDIP 63 AI GSFDPIT GHLDII+RG ++FD+VYV VL N +K+P FSV+ERL+ I +A +P Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 64 NVKVDSHSGLLVEYAKMRNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQ 123 N +VDS GL V YA+ R A AILRGLR +SDFE E+Q+ + N+ L ++ET F+ T+ + Sbjct: 62 NAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTE 121 Query: 124 YSFLSSSIVKEVARYGGSVVDLVPPVVERALKEKF 158 YSFLSSS+VKEVAR+GG+V VP V AL ++F Sbjct: 122 YSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQF 156
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 26.1 bits (57), Expect = 0.019 Identities = 9/34 (26%), Positives = 19/34 (55%), Gaps = 2/34 (5%) Query: 47 MEQIEHMMQKLNKLPFVKKIEQSYRPYLKTEFEN 80 +EQI+ +Q+L ++++ S+ Y+ F N Sbjct: 297 IEQIQSKIQELGDT--LEELRDSFDGYINNAFVN 328
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 27.0 bits (59), Expect = 0.030 Identities = 10/27 (37%), Positives = 17/27 (62%) Query: 65 SSVKENKKEKDNRTEEEKTADVMGQML 91 S +K N K + N+TE+EK D + ++ Sbjct: 41 SDIKRNHKTEKNKTEKEKFKDSINNLV 67
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 181 bits (461), Expect = 2e-51 Identities = 101/476 (21%), Positives = 195/476 (40%), Gaps = 96/476 (20%) Query: 8 LRNIAIIAHVDHGKTTLVDQLLRQAGTFRANEHVEE--RAMDSNDLERERGITILAKNTA 65 + NI ++AHVD GKTTL + LL +G V++ D+ LER+RGITI T+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 66 IHYEDKRINILDTPGHADFGGEVERIMKMVDGVLLVVDAYEGCMPQTRFVLKKALEQNLT 125 +E+ ++NI+DTPGH DF EV R + ++DG +L++ A +G QTR + + + Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 126 PIVVVNKIDRDFARPDEVVDEVIDLF---------IELG-------------------AN 157 I +NKID++ V ++ + +EL N Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182 Query: 158 EDQLE--------------------------FPVVFASAMNGTASLDSNPANQEENMKSL 191 +D LE FPV SA N + +L Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNN------------IGIDNL 230 Query: 192 FDTIIEHIPAPIDNSEEPLQFQVALLDYNDYVGRIGVGRVFRGTMKVGQQVALMKVDGSV 251 + I + + L +V ++Y++ R+ R++ G + + V + + + Sbjct: 231 IEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKE--- 287 Query: 252 KQFRVTKLFGYMGLKRQEIEEAKAGDLVAVSGMEDINVGETVCPVEHQDALPLLRIDEPT 311 + ++T+++ + + +I++A +G++V + E + + + + + P Sbjct: 288 -KIKITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPL 345 Query: 312 LQMTFLVNNSPFAGREGKYITSRKIEER------LRSQLETDVSLRVDNTESPDAWIVSG 365 LQ T + K ++R L ++D LR + I+S Sbjct: 346 LQTT---------------VEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSF 390 Query: 366 RGELHLSILIENMRRE-GYELQVSKPEVIIKEVDGVRCEPVERVQIDVPEEYTGSI 420 G++ + + ++ + E+++ +P VI E + E +++ P + SI Sbjct: 391 LGKVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVP-PNPFWASI 445 Score = 39.8 bits (93), Expect = 3e-05 Identities = 17/77 (22%), Positives = 28/77 (36%), Gaps = 1/77 (1%) Query: 403 EPVERVQIDVPEEYTGSIMESMGARKGEMLDMVNNGNGQVRLTFMVPARGLIGYTTEFLT 462 EP +I P+EY ++D N +V L+ +PAR + Y ++ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNN-EVILSGEIPARCIQEYRSDLTF 595 Query: 463 LTRGYGILNHTFDCYQP 479 T G + Y Sbjct: 596 FTNGRSVCLTELKGYHV 612
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.4 bits (68), Expect = 6e-04 Identities = 14/47 (29%), Positives = 19/47 (40%), Gaps = 9/47 (19%) Query: 21 GAIMEELEVGVLGFVASCVSALFF--------GLFG-AIPISILCAF 58 + LE S V AL F G++G AI ILC++ Sbjct: 461 KPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSY 507
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 27.5 bits (61), Expect = 0.025 Identities = 8/25 (32%), Positives = 12/25 (48%) Query: 140 GEIVEILVNNGQLVEYGQPLFLVKA 164 + EI+V G+ V G L + A Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTA 129
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.7 bits (79), Expect = 4e-04 Identities = 28/114 (24%), Positives = 40/114 (35%), Gaps = 7/114 (6%) Query: 104 KENKETAEQEETVVEATPKKEVVVEVPKAVTPAPKPVTRVETPAIASTPKPTPAPT--PK 161 E KETA E+ +A + E EVPK + + ET + P PT K Sbjct: 1098 TETKETATVEKEE-KAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK 1156 Query: 162 PVSVEAAVELSTPAPVKK---AVPTPVTKQETTPVAPVKPKQSALTETNSKLQE 212 + T P K+ V PVT+ T ++ T + Q Sbjct: 1157 EPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGN-SVVENPENTTPATTQP 1209 Score = 32.7 bits (74), Expect = 0.002 Identities = 21/96 (21%), Positives = 31/96 (32%), Gaps = 10/96 (10%) Query: 105 ENKETAEQEETVVEATPKKEVVVEVPKAVTPAPKPVTRV----------ETPAIASTPKP 154 E ++T E + + +PK+E V PA + V T K Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKE 1174 Query: 155 TPAPTPKPVSVEAAVELSTPAPVKKAVPTPVTKQET 190 T + +PV+ V TP T Q T Sbjct: 1175 TSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPT 1210
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 30.0 bits (67), Expect = 0.008 Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 8/98 (8%) Query: 93 VIVSEDHPNMPKTVTEAYRVISQGLLDGFKALGLE-AYYAVPKTEADRENLKNPRSG-VC 150 V V + +P+T AY + K LGLE A Y + R N+ +P S Sbjct: 140 VTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI------RCNIVSPGSTETD 193 Query: 151 FDAPSWYEIVVEGRKIAGSAQTRQKGVILQHGSIPLEI 188 W + + I GS +T + G+ L+ + P +I Sbjct: 194 MQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDI 231
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.2 bits (148), Expect = 6e-14 Identities = 39/203 (19%), Positives = 71/203 (34%), Gaps = 25/203 (12%) Query: 2 TANRIKAVALSHFARYGYEGTSLANIAQEVGIKKPSIYAHFKGKEELYFICLESALQKDL 61 T I VAL F++ G TSL IA+ G+ + +IY HFK K +L+ E + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 62 QSFTDDIENFSNSSTEELLLQLLKGYAKRFGESEESMFWLRTSYFPPDAFRE-QIIEK-- 118 + + F +L ++L + E + + + E ++++ Sbjct: 72 ELELEYQAKFP-GDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 119 ANAHIENVGKLLFPIFKQANEKSELH-NIEVKDALEAFLCLLDGLM-------------- 163 N +E+ ++ K E L ++ + A + GLM Sbjct: 131 RNLCLESYDRIE-QTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKK 189 Query: 164 -----VELLFAGLNRFETRLNAS 181 V +L T N + Sbjct: 190 EARDYVAILLEMYLLCPTLRNPA 212
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 33.0 bits (75), Expect = 4e-04 Identities = 17/90 (18%), Positives = 32/90 (35%) Query: 8 GIQYMQEGNWEEAAKNFTEAIEENPKDALGYINFANLLDVLGDSERAILFYKRALELDDK 67 Q G +E+A K F + D+ ++ +G + AI Y +D K Sbjct: 43 AFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIK 102 Query: 68 SAAAYYGLGNVYYGQEQFAEAKAVFEQAMQ 97 + + + AEA++ A + Sbjct: 103 EPRFPFHAAECLLQKGELAEAESGLFLAQE 132 Score = 31.1 bits (70), Expect = 0.002 Identities = 17/96 (17%), Positives = 27/96 (28%) Query: 109 LGITHVQLGNDRLALPFLQRATELDENDVEAVFQCGLCFARLEHIQEAKPYFEKVLEMDE 168 L Q G A Q LD D G C + A + MD Sbjct: 42 LAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDI 101 Query: 169 EHADAYYNLGVAYVFEENNEKALALFKKATEIQPDH 204 + ++ + + +A + A E+ D Sbjct: 102 KEPRFPFHAAECLLQKGELAEAESGLFLAQELIADK 137
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.5 bits (66), Expect = 0.028 Identities = 25/123 (20%), Positives = 46/123 (37%), Gaps = 8/123 (6%) Query: 114 GFEVTYLPVDETGRVQVSDIQKAL-TEETILVSVMFGNNEVGTMQPIAEIGKLLKEHQAY 172 G++ + E +S K E ++L++ + +G + + G ++Y Sbjct: 444 GYDARHAAFLEDNFKILSQYNKEYSVERSVLITQQHWDTLIGELAGVTRNGDKTLSGKSY 503 Query: 173 FHTDAVQAYGLVEINVKEFGIDLLSISAHKINGPKGVGFLYAGTNVKF-EPLLIGGEQER 231 D + +E EF + I+ T +KF PLL GE+ R Sbjct: 504 --IDYYEEGKRLEKKXDEFQKQVFDPLKGNIDLSDSKS----STLLKFVTPLLTPGEEIR 557 Query: 232 KRR 234 +RR Sbjct: 558 ERR 560
>PF05043#Transcriptional activator Length = 493 Score = 25.3 bits (55), Expect = 0.020 Identities = 9/32 (28%), Positives = 14/32 (43%) Query: 32 FISKEQNNTSMELASEFGISLQDVKRLKKQIE 63 FI + + + EF IS + R+ QI Sbjct: 94 FIFFNEGCQAESICKEFYISSSSLYRIISQIN 125
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 28.4 bits (63), Expect = 0.010 Identities = 24/118 (20%), Positives = 46/118 (38%), Gaps = 16/118 (13%) Query: 16 DGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLS 75 DG+ +PF + V + HE T + + A L ++++ESG +N ++ D+ G ++ Sbjct: 352 DGDGQTFLPFSGGIDV-VGHELTHA----VTDYTAGL-VYQNESGAINEAMSDIFGTLVE 405 Query: 76 ----------ISQFTLYGDCRKGRRPNFMDAAKPDYAEHLYDFFNEEVRKQGLHVETG 123 I + + D AK +H + G+H +G Sbjct: 406 FYANRNPDWEIGEDIYTPGVAGDALRSMSDPAKYGDPDHYSKRYTGTQDNGGVHTNSG 463
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 270 bits (691), Expect = 2e-86 Identities = 100/318 (31%), Positives = 165/318 (51%), Gaps = 21/318 (6%) Query: 443 PTKFDRINFVNVGHKFLIFSIVVVIAGAIILPIFKLNLGIDFASGTRIDLQSKQSVTVSD 502 P K + +F +IV++IA I+ + LN GIDF GT I +S ++ V Sbjct: 9 PEKTN-FDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGV 67 Query: 503 VHKDFKELNID---VKEENIVPTGDDNKGFAVR-----------TLGVLSKDEIAKTKTF 548 + L + + E +D +R G ++ + K +T Sbjct: 68 YRAALEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETA 127 Query: 549 FH--DKYGTDPNVSTVSPTIGKEIARNAFIAVLIASAVIILYVSIRFRFTYALSAVLALL 606 D + +V P + E+ A ++L A+ VI+ Y+ +RF + +AL AV+AL+ Sbjct: 128 LTAVDPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALV 187 Query: 607 HDAFVMIVIFSIFQLEVDLTFIAAVLTIIGYSINDSIVTFDRNRELYKQKKRVRDIKDLE 666 HD + + +F++ QL+ DLT +AA+LTI GYSIND++V FDR RE + K L Sbjct: 188 HDVLLTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKT----MPLR 243 Query: 667 EIVNASIRQTLGRSINTVLTVLFPVIALLIFGSESLRNFSFALLVGLVVGTYSSVFVASQ 726 +++N S+ +TL R++ T +T L ++ +LI+G + +R F FA++ G+ GTYSSV+VA Sbjct: 244 DVMNLSVNETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKN 303 Query: 727 IWLMLENRRLKKGKNKKK 744 I L + R K+ K+ Sbjct: 304 IVLFIGLDRNKEKKDPSD 321 Score = 66.0 bits (161), Expect = 1e-13 Identities = 38/180 (21%), Positives = 84/180 (46%), Gaps = 11/180 (6%) Query: 249 SVGAKFGQQALEQTIFASAIGIALIFLFMLV-FYRLPGLVAVIMLGLYIFVTLLVFNWMH 307 SVG K + + +++ +I ++ V F L AV+ L + +T+ +F + Sbjct: 142 SVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTVGLFAVLQ 201 Query: 308 AVLTLPGIAALVLGVGIAVDANIITYERLKEELKIGKSMM------SAFRAGNHRSLATI 361 L +AAL+ G +++ ++ ++RL+E L K+M + R++ T Sbjct: 202 LKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETLSRTVMTG 261 Query: 362 LDANITTLAAAGVLFVYGNSSVKGFATSLIVSILVGFITNVFGTRFLLSLLVKSRYFDKK 421 + TTL A + ++G ++GF +++ + G ++V+ + ++ + R +KK Sbjct: 262 M----TTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLDRNKEKK 317
>PF06580#Sensor histidine kinase Length = 349 Score = 27.5 bits (61), Expect = 0.006 Identities = 8/39 (20%), Positives = 19/39 (48%) Query: 7 NIVMIVAMFAIFYFLLIRPQQKRQKAVAQMQSELKKGDA 45 N+V++ M+++ YF + +Q + Q + +A Sbjct: 123 NVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEA 161
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 26.0 bits (57), Expect = 0.011 Identities = 13/59 (22%), Positives = 30/59 (50%), Gaps = 5/59 (8%) Query: 1 MTEMPKLLITAGILLIVVGLAWKFIGRLPGDIFVKKGNVTFYFPIITCIVLSIVLSFIM 59 M+++ L+ ++L V + F G G I+ + F I++ + LS++++ I+ Sbjct: 435 MSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQ-----FSITIVSAMALSVLVALIL 488
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 497 bits (1281), Expect = e-180 Identities = 194/336 (57%), Positives = 252/336 (75%), Gaps = 5/336 (1%) Query: 4 FGGFTRDLGIDLGTANTLVYVKGKGVVLREPSVVALQTD----TKQIVAVGSDAKQMIGR 59 G F+ DL IDLGTANTL+YVKG+G+VL EPSVVA++ D K + AVG DAKQM+GR Sbjct: 6 RGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGR 65 Query: 60 TPGNVVALRPMKDGVIADYETTATMMKYYIQQAQKSNGFFSRKPYVMVCVPSGITAVERR 119 TPGN+ A+RPMKDGVIAD+ T M++++I+Q SN F P V+VCVP G T VERR Sbjct: 66 TPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQV-HSNSFMRPSPRVLVCVPVGATQVERR 124 Query: 120 AVIDATRQAGARDAYPIEEPFAAAIGANLPVWEPTGSMVVDIGGGTTEVAIISLGGIVTS 179 A+ ++ + AGAR+ + IEEP AAAIGA LPV E TGSMVVDIGGGTTEVA+ISL G+V S Sbjct: 125 AIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYS 184 Query: 180 QSVRVAGDDMDDSIIQYIKKSYNLMIGERTAEALKLEIGSAGEPEGIEPMEIRGRDLVSG 239 SVR+ GD D++II Y++++Y +IGE TAE +K EIGSA + + +E+RGR+L G Sbjct: 185 SSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEG 244 Query: 240 LPKTVLIQPEEIADALKDTVDAIVESVKNTLEKTPPELAADIMDRGIVLTGGGALLRNLD 299 +P+ + EI +AL++ + IV +V LE+ PPELA+DI +RG+VLTGGGALLRNLD Sbjct: 245 VPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLD 304 Query: 300 KVISEETNMPVLVAEDPLDCVAIGTGKALDNIDLFK 335 +++ EET +PV+VAEDPL CVA G GKAL+ ID+ Sbjct: 305 RLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHG 340
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 31.0 bits (70), Expect = 0.004 Identities = 32/157 (20%), Positives = 54/157 (34%), Gaps = 25/157 (15%) Query: 146 AVLAKTAVSQAKAGADIIAPSNMMDGFVTAIRHALDENGFGHVPVMSYAVKYSSAFYGPF 205 +V A + V+ A +D N M GF R+ D + G + +Y K +A G + Sbjct: 21 SVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDY 80 Query: 206 RDAAHGAPQFGDRKTYQMDPANRME-----------AFREAESDVMEGADFLIVKPALSY 254 + G PA R+ + + ++ SY Sbjct: 81 NKNQYYGITAG--------PAYRINDWASIYGVVGVGYGKFQTTEYPTYKHDTSDYGFSY 132 Query: 255 LDIVRDVKNNFN-LPVVAYNVSGEYSMIKAAAQNGWI 290 ++ FN + VA + S E S I++ WI Sbjct: 133 GAGLQ-----FNPMENVALDFSYEQSRIRSVDVGTWI 164
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 27.9 bits (62), Expect = 0.027 Identities = 18/90 (20%), Positives = 37/90 (41%), Gaps = 13/90 (14%) Query: 58 KTQTLNFFLINEMMHFVDVPGYGYAKVSKTERAAWGKMIETYFTTREQLDAAVLVVDLRH 117 +T +F N ++ +D PG+ +++ R+ LD A+L++ + Sbjct: 57 QTGITSFQWENTKVNIIDTPGH-MDFLAEVYRSL------------SVLDGAILLISAKD 103 Query: 118 KPTNDDVMMYDFLKHYDIPTIIIATKADKI 147 +++ L+ IPTI K D+ Sbjct: 104 GVQAQTRILFHALRKMGIPTIFFINKIDQN 133
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.5 bits (87), Expect = 2e-04 Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 14/101 (13%) Query: 352 LCLVGPPGVGKTSLARSI-ATSLNRN--FVRVSLGGVRD---ESEIRGHRRTYVGAMPGR 405 L + G G GK +AR++ RN FV +++ + ESE+ GH + GA G Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEK---GAFTGA 219 Query: 406 IIQGMKKAKSVNP-VFLLDEIDKMSNDFRGDPSAALLEVLD 445 + + + LDEI M D + LL VL Sbjct: 220 QTRSTGRFEQAEGGTLFLDEIGDMPMDAQ----TRLLRVLQ 256
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 58.3 bits (141), Expect = 4e-11 Identities = 43/214 (20%), Positives = 76/214 (35%), Gaps = 41/214 (19%) Query: 44 ELEQLRKMREISLTEPLAEKVR----PTSFLDIVGQEDGIKSLK--AALCGPNPQHVIIY 97 +L +L + +L EP + + +VG+ ++ + A ++I Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT 166 Query: 98 GPPGVGKTAAARLVLEEAKRNPKSPFRTNATFIELDATTARFDERGIADPLIGSVHDPIY 157 G G GK AR + + KR F+ ++ A I L G Sbjct: 167 GESGTGKELVARALHDYGKRRNGP-------FVAINM--AAIPRDLIESELFGHE----- 212 Query: 158 QGAGAMGQAGIPQPKKGAVTDAHGGILFIDEIGELHPIQMNKMLKVLEDRKVFLESAYYS 217 GA G G A GG LF+DEIG++ ++L+VL+ + Sbjct: 213 --KGAF--TGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGG--- 265 Query: 218 EENTMIPTYIHDIFQKGLPADFRLVGATTRSPEE 251 + + +D R+V AT + ++ Sbjct: 266 --------------RTPIRSDVRIVAATNKDLKQ 285
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 113 bits (283), Expect = 2e-33 Identities = 36/192 (18%), Positives = 75/192 (39%), Gaps = 10/192 (5%) Query: 5 RPKYNQIIDAAVIVIAENGYHQAQVSKIAKQAGVADGTIYLYFKNKEDILISLFQEKMGE 64 + I+D A+ + ++ G + +IAK AGV G IY +FK+K D+ +++ Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 65 FVETIRQKTAGIESAVSKLFMLVETHFLLLSQNDPL--AIVTQLELRQSNQDLRLKINEV 122 E + A + + H L + + ++ + + + + Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 123 LKGY----LQVIDEILETGIKQGEFQADLNVRVARQMIFGTVDEVVTNWVMSDHKYDLVA 178 + I++ L+ I+ ADL R A ++ G + ++ NW+ + +DL Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDL-- 187 Query: 179 LSKTVHGLLIAA 190 K +A Sbjct: 188 --KKEARDYVAI 197
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 183 bits (465), Expect = 5e-58 Identities = 62/258 (24%), Positives = 115/258 (44%), Gaps = 11/258 (4%) Query: 52 AKKVVVLEWVYSEDLLALGVQPVGMADIKNYNKWVNTKTKPSKDVVDVGTRQQPNLEEIS 111 ++V LEW+ E LLALG+ P G+AD NY WV+ P V+DVG R +PNLE ++ Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLP-DSVIDVGLRTEPNLELLT 93 Query: 112 RLKPDLIITASFRGKAIKNELEQIAPTVMFDPSTSNNDHFAEMTETFKQIAKAVGKEEEG 171 +KP ++ S L +IAP F+ S A ++ ++A + + Sbjct: 94 EMKPSFMVW-SAGYGPSPEMLARIAPGRGFNFSDGKQP-LAMARKSLTEMADLLNLQSAA 151 Query: 172 KKVLADMDKAFADAKAKIEKADLKDKNIAMAQAFTAKNVPTFRILTDNSLALQVTKKLGL 231 + LA + K + K + + + +++ + NSL ++ + G+ Sbjct: 152 ETHLAQYEDFIRSMKPRFVKRGARP--LLLTTLIDPRHM---LVFGPNSLFQEILDEYGI 206 Query: 232 TNTFEAGKSEPDGFKQTTVESLQSVQDSNFIYIVADEDNIFDTQLKGNPAWEELKFKKEN 291 N ++ G++ G +++ L + +D + + D D L P W+ + F + Sbjct: 207 PNAWQ-GETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMD-ALMATPLWQAMPFVRAG 264 Query: 292 KMYKLKGDTWIFGGPESA 309 + ++ W +G SA Sbjct: 265 RFQRVP-AVWFYGATLSA 281
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.4 bits (86), Expect = 2e-04 Identities = 35/118 (29%), Positives = 60/118 (50%), Gaps = 11/118 (9%) Query: 518 KIENMIAKLEE-------SQKNAERDWNEAEALRKQSEKLHREL--QRQIIEFNEERDER 568 ++E KLEE S+++ RD + + +KQ E H++L Q +I E + + R Sbjct: 327 QLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRR 386 Query: 569 LLKAQKEGEEKVEAAKKEAEGIIQELRQLRKAQLANVK--DHELIEAKSRLEGAAPEL 624 L A +E +++VE A +EA + L +L K + K + E E +++LE A L Sbjct: 387 DLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKAL 444
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 24.3 bits (53), Expect = 0.033 Identities = 10/33 (30%), Positives = 15/33 (45%), Gaps = 1/33 (3%) Query: 19 DQLQETIVDAIQSGEEKMLPGLGVLFEVIWKNA 51 D + + + GE+ L G G FEV + A Sbjct: 27 DAVFSAVSSYLAKGEKVQLIGFGN-FEVRERAA 58
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 146 bits (369), Expect = 4e-40 Identities = 86/400 (21%), Positives = 174/400 (43%), Gaps = 14/400 (3%) Query: 108 FVSILNQTIINVALPPLMNEFNVSTSTAQWLITGFMLVNGILVPISAFLVSRFTYRKLFV 167 F S+LN+ ++NV+LP + N+FN ++ W+ T FML I + L + ++L + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 168 AAMLFFTVGSIICATSGN-FTMMMTGRVIQAVGAGILMPVGMNIFMTLFPPHKRGAAMGL 226 ++ GS+I + F++++ R IQ GA + M + P RG A GL Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 227 LGVAMILAPAIGPTVTGWVIENYSWNLMFYAMFIIGLIITFLSLKFFTLAQPVSNTKLDI 286 +G + + +GP + G + W+ + I IIT L + DI Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMI--TIITVPFLMKLLKKEVRIKGHFDI 201 Query: 287 FGVVSSSIGLGSLLYGFSEAGNNSWTSAEVIISLVIGVIGLALFIWRELTTDNKMLDLQV 346 G++ S+G+ + + S + L++ V+ +F+ + +D + Sbjct: 202 KGIILMSVGIVFFMLF---TTSYSIS------FLIVSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 347 FKYPVFTFTLVINAIVTMALFGGMLLLPVYLQNIRGFTPIESG-LLLLPGSLIMGIMGPV 405 K F ++ I+ + G + ++P ++++ + E G +++ PG++ + I G + Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 406 AGKLFDKYGIRPLAIIGLAITTYATYEFTKLSMDTPYSVIMTDYIIRSIGMSFIMMPIMT 465 G L D+ G + IG+ + + + L T + + + G+SF I T Sbjct: 313 GGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSW-FMTIIIVFVLGGLSFTKTVIST 371 Query: 466 AGMNALPMKLISHGTATQNTSRQVAGSIGTAILITLMTQQ 505 ++L + G + N + ++ G AI+ L++ Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 79.1 bits (195), Expect = 3e-19 Identities = 29/135 (21%), Positives = 49/135 (36%), Gaps = 12/135 (8%) Query: 87 QTVDVTIPQNATVVQSNATT-NAFVGAGSPI-AYAFDMNNLWVTANIEETDVDDVQKGQD 144 Q + P + V Q T V + + + L VTA ++ D+ + GQ+ Sbjct: 326 QASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQN 385 Query: 145 VDVYVDAYPDTT---LTGKVEQVGLTTANTFSMLPSSNATANYTKVTQVVPVKISLDHSK 201 + V+A+P T L GKV+ + L V + +K Sbjct: 386 AIIKVEAFPYTRYGYLVGKVKNINLDAI-------EDQRLGLVFNVIISIEENCLSTGNK 438 Query: 202 SVNIVPGMNVTVRIH 216 ++ + GM VT I Sbjct: 439 NIPLSSGMAVTAEIK 453
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.0 bits (145), Expect = 2e-13 Identities = 24/100 (24%), Positives = 39/100 (39%), Gaps = 6/100 (6%) Query: 9 PRVKRTRQLIQDAFVALVGEKGFENVTVQHIAERAPVNRATFYSHYHDKYDLLDKSIEEM 68 + TRQ I D + L ++G + ++ IA+ A V R Y H+ DK DL + E Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 69 LEKLTEVIKPKNRNKEDFQLAFDSPHPNFLALFEHIAENA 108 + E+ E P + H+ E+ Sbjct: 67 ESNIGELE------LEYQAKFPGDPLSVLREILIHVLEST 100
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 39.5 bits (92), Expect = 1e-06 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 3/74 (4%) Query: 70 DNILGCYIAYSKSISGK--IEVLFVDEKHRGNGFGLKLMNSAVEWFKAKKIDEIELTVVY 127 +N I + +G IE + V + +R G G L++ A+EW K + L Sbjct: 73 ENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQD 132 Query: 128 GN-EAISFYEKLGF 140 N A FY K F Sbjct: 133 INISACHFYAKHHF 146
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 27.5 bits (61), Expect = 0.020 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 2/69 (2%) Query: 7 KQKQAKRQKYIKKKQEQNIPLSKKVVLMIEKTFRYICMALYVILCMYSFGVFYSLEITPN 66 K K K K K IP KK+++ E F+Y A Y + Y + + E TP Sbjct: 177 TDKLDKLDKESKDKF-NKIPAEKKLIVTSEGAFKYFSKA-YGVPSAYIWEINTEEEGTPE 234 Query: 67 IIESILEFL 75 I++++E L Sbjct: 235 QIKTLVEKL 243
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 82.0 bits (202), Expect = 1e-20 Identities = 65/264 (24%), Positives = 107/264 (40%), Gaps = 19/264 (7%) Query: 1 MNYSNLKGGRFVRHALITAGTKGLGKQVTEKLLAKGYSVTVTYHSDITAMKKMKETYKNM 60 MN ++G + A IT +G+G+ V L ++G + + ++K+ + K Sbjct: 1 MNAKGIEG----KIAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAE 55 Query: 61 EERLQFVQADVTKKEDLHKIVEEAISRFGKIDFLINNAGPYVFERKKLVDYEEDEWNEMI 120 + ADV + +I G ID L+N AG V + ++EW Sbjct: 56 ARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAG--VLRPGLIHSLSDEEWEATF 113 Query: 121 QGNLTAVFHLLKLVVPIMRKQNFGRIINYGFQGADSAPGWIYRSAFAAAKVGLVSLTKTV 180 N T VF+ + V M + G I+ G A +A+A++K V TK + Sbjct: 114 SVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPR--TSMAAYASSKAAAVMFTKCL 171 Query: 181 AYEEAEYGITANMVCPGDIIGEMK----------EATIQEARQLKERNTPIGRSGTGEDI 230 E AEY I N+V PG +M+ E I+ + + + P+ + DI Sbjct: 172 GLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDI 231 Query: 231 ARTISFLCEEDSDMITGTIIEVTG 254 A + FL + IT + V G Sbjct: 232 ADAVLFLVSGQAGHITMHNLCVDG 255
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 29.3 bits (65), Expect = 0.009 Identities = 20/71 (28%), Positives = 38/71 (53%), Gaps = 4/71 (5%) Query: 104 VTDEIENNADKVAQVVQWSSAAIEVY---NHYRATRQEKKVEKEERKLERLEKKAEKK-E 159 + D + +N + V + + ++ A + N+ + +K +EK RK E LEK+ EKK E Sbjct: 574 IKDFLSSNKELVGKTLNFNKAVADAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLE 633 Query: 160 KRSRLRMRGES 170 +S + + E+ Sbjct: 634 SKSGNKNKMEA 644
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 63.5 bits (154), Expect = 5e-12 Identities = 56/328 (17%), Positives = 96/328 (29%), Gaps = 35/328 (10%) Query: 553 PVVEGQSVVEEAPIAEEQPVAEETSVVEEQPVAEETSIVEEQPVAEEAPVVE-EQPVVQK 611 P VE ++ + P + V EE + V+E PV AP E Sbjct: 983 PEVEKRNQTVDTTNIT-TPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA 1041 Query: 612 EEPKREKKRHVPFNVVMLKQDRARLMERHASRTNGMQSSMSERVENKPVHQVEEQPQVEE 671 E K+E K E+ A+ T +++ E + V+ Sbjct: 1042 ENSKQESKT-------------VEKNEQDATETTAQNREVAK----------EAKSNVKA 1078 Query: 672 KPMQQVV--VEPQVEEKQMQQVVEPQVEEKPMQQVVVEPQVEEKPMQQVVVEPQVEEKPM 729 V + +E Q + E EK + V + +E P V P+ E+ Sbjct: 1079 NTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSET 1138 Query: 730 QQVVVEPQVEEKPM------QQVVVEPQVEEKPMQQVVVEPQVEEKPMQQVVVEPQVEEK 783 Q EP E P Q E+P ++ + V V E Sbjct: 1139 VQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVEN 1198 Query: 784 PVQ-QVVEPQVEEVQPVQQVVAEQVQKPISSTEVEEKAYVVNQRENDVRNVLQTPPTYTI 842 P Q + ++ + S + + + + T T Sbjct: 1199 PENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTN 1258 Query: 843 PSLT-LLSIPQQAALDNTEWLEEQKELL 869 L+ + Q AL+ + + + L Sbjct: 1259 AVLSDARAKAQFVALNVGKAVSQHISQL 1286 Score = 63.2 bits (153), Expect = 7e-12 Identities = 61/283 (21%), Positives = 95/283 (33%), Gaps = 40/283 (14%) Query: 311 EEIKRSTEIEQPTIEVEKQAPEESVIVKAEEKLE-ETIVVEIPEEVEVIAEAEEPEEVEV 369 E+ ++ + T QA SV EE + V P A A E E Sbjct: 986 EKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPP------APATPSETTET 1039 Query: 370 IAETEESEEVEVIAETEESEEV-------------EVIAETEELEEVEVTAETEELEEVE 416 +AE + E V +++ E V A T+ E + +ET+E + E Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 417 VVAETEELEEVEVIAETEKLEELEEV--EVIAETEESEEVEVIAETEAPEEVEPVALEEM 474 +E + ETEK +E+ +V +V + E+SE V+ AE A E V ++E Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEP-ARENDPTVNIKEP 1158 Query: 475 QQEMVLNEAIEQKNEFIHVAVADEQTKKDVQSFADVLIAEEQSVVEETPIVEEQPVAEEA 534 Q + EQ + V T E + V V E P Sbjct: 1159 QSQTNTTADTEQPAKETSSNVEQPVT--------------ESTTVNTGNSVVENPENTTP 1204 Query: 535 PVVEEQSVVEETPIVEEAPVVEGQSV---VEEAPIAEEQPVAE 574 + E + + +SV VE A + Sbjct: 1205 ATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTV 1247 Score = 48.1 bits (114), Expect = 3e-07 Identities = 45/223 (20%), Positives = 75/223 (33%), Gaps = 21/223 (9%) Query: 214 EQGERQYEESKKEEKSVVDQWLEKNGYEIERQEPIVEEKEVVQEMSAPQEVPAAELLHET 273 E E E SK+E K+V E++ E Q V ++ + Q A+ ET Sbjct: 1035 ETTETVAENSKQESKTVEKN--EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET 1092 Query: 274 IAERMEGAKQESDVVDKNILQEELVDSKVEHEDTILSEEIKRSTEIEQPTIEVEKQAPEE 333 + K+ + E+ +KVE E T +E+ + T P KQ E Sbjct: 1093 KETQTTETKETAT-------VEKEEKAKVETEKT---QEVPKVTSQVSP-----KQEQSE 1137 Query: 334 SVIVKAEEKLEETIVVEIPEEVEVIAEAEEPEEVEVIAETEESEEVEVIAETEESEEVEV 393 +V +AE E V I E ++ + E A+ S + + E+ Sbjct: 1138 TVQPQAEPARENDPTVNIKEPQ---SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194 Query: 394 IAETEELEEVEVTAETEELEEVEVVAETEELEEVEVIAETEKL 436 + E E T + E + V + + Sbjct: 1195 VVENPE-NTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEP 1236 Score = 46.6 bits (110), Expect = 7e-07 Identities = 54/266 (20%), Positives = 83/266 (31%), Gaps = 35/266 (13%) Query: 423 ELEEVEVIAETEKLEELEEVEVIAETEESEEVEVIAETEAPEEVEPVALEEMQQEMVLNE 482 E+E+ +T + ++ + S E+ EAP A E V E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETV-AE 1042 Query: 483 AIEQKNEFIHVAVADEQTKKDVQS------FADVLIAEEQSVV----EETPIVEEQPVAE 532 +Q+++ + D ++V + + V ET + E Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 533 EAPVVEEQSVVEETPIVEEAPVVEGQSVVEEAPIAEEQPVAE------------------ 574 A V +E+ ET +E P V Q ++ QP AE Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQT 1162 Query: 575 ETSVVEEQPVAEETSIVEEQPVAEEAPV-----VEEQPVVQKEEPKREKKRHVPFNVVML 629 T+ EQP A+ETS EQPV E V V E P + N Sbjct: 1163 NTTADTEQP-AKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKN 1221 Query: 630 KQDRARLMERHASRTNGMQSSMSERV 655 + R+ H S+ V Sbjct: 1222 RHRRSVRSVPHNVEPATTSSNDRSTV 1247
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 31.1 bits (70), Expect = 0.017 Identities = 27/120 (22%), Positives = 39/120 (32%), Gaps = 13/120 (10%) Query: 482 TGSTGPTGSTGTTG-NTGVTGDTGPTGATGVSTTATYAFANNTSGSVISVLLGGTNIPLP 540 G P T T G GV GD T S Y +NT GS I G Sbjct: 220 PGGAQPVAGTSTVGVGRGVLGDQKYINTTYSSYYGYYYLQDNTRGSGIFTYDG------- 272 Query: 541 NNQNIGPGITVSGGNTVFTV-----ANAGNYYIAYTINLTAGLLVSSRITVNGSPLAGTI 595 N+ + PG + G+ F A +YY + + + + + T+ Sbjct: 273 RNRTVLPGSLWADGDNQFFASYDAAAVDAHYYAGVVYDYYKNVHGRLSYDGSNAAIRSTV 332
>PF07675#Cleaved Adhesin Length = 1358 Score = 24.7 bits (53), Expect = 0.045 Identities = 13/41 (31%), Positives = 18/41 (43%) Query: 33 VYAGAGGSSAAIFLNGKRQPEAVIRTSVFLPPLATSTRTLG 73 VYA + G+ A+ F N + +T V P TR G Sbjct: 1175 VYASSTGNDASNFANALLEEVLTAKTVVTAPEAIRGTRAQG 1215
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 47.0 bits (111), Expect = 3e-07 Identities = 38/253 (15%), Positives = 86/253 (33%), Gaps = 12/253 (4%) Query: 9 KKKLNTTEKNETDNSEQKPNNQEDDNKEQTRSTKHNKSNNSEQKKEEHKESSQDKQQNQS 68 K++ T EKNE D +E N+E KE + K N N + + +Q + ++ Sbjct: 1045 KQESKTVEKNEQDATETTAQNREVA-KEAKSNVKANTQTNEVAQSGSETKETQTTETKET 1103 Query: 69 NQNQQQSAKQDESSQGQQNHSKQDDSDQGQQQHSKQGNSDQGQQQHSKQGDSNQGQQNHS 128 +++ + E+ + Q+ Q+Q + +++ + + Q + Sbjct: 1104 ATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTN 1163 Query: 129 KQNDSDQGQQQHSKQDESSQEQQNHSKQDDS----DQGQQQHSKQDESSQEQQNHSKQDD 184 D++Q ++ S E + +S + + Q + E N K Sbjct: 1164 TTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRH 1223 Query: 185 SDQGQQQHSKQDESSQEQQNHSKQDDSDQDDSFQDTQQSSKQD-------DLAQDKQQHS 237 + + ++ + S D + + S + ++ + QH Sbjct: 1224 RRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHI 1283 Query: 238 KQDNSDQDKQQNS 250 Q + + Q N Sbjct: 1284 SQLEMNNEGQYNV 1296
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 55.2 bits (133), Expect = 2e-10 Identities = 54/321 (16%), Positives = 118/321 (36%), Gaps = 10/321 (3%) Query: 42 GMVLMINSLTGVIGNLLGGVLFDKWGGYKSTLVGIVITLVSILGLVFFHG-WPLYVVWLA 100 G++L + +L + G L D++G LV + V + W LY+ Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIG--R 103 Query: 101 LIGFGSGMVFPSMYAMVGTVWPEGGR-RAFNAMYVGQNVGIAIGTACGGLVASYRFDYIF 159 ++ +G A + + R R F M G+ G GGL+ + F Sbjct: 104 IVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPF 163 Query: 160 LANFILYFVFFLIAFIGFR-GMEDKKEPGVQKEVEAKKGWSLTPGFKALLIVCVAYALCW 218 A L + FL + ++ P ++ + + G + + + + Sbjct: 164 FAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQ 223 Query: 219 VTYVQWQGAIATHMQE-LNISLRHYSLLWTINGAMIVCAQPLVSMLIRWMKR-SLKQQIM 276 + ++ + + G + AQ +++ R ++ +M Sbjct: 224 LVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITG--PVAARLGERRALM 281 Query: 277 IGILIFAVSFIVLSQAQQFTMFLVAMVTLTIGELFVWPAVPTIANILAPKDKLGFYQGVV 336 +G++ +I+L+ A + M MV L G + + PA+ + + +++ G QG + Sbjct: 282 LGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM-PALQAMLSRQVDEERQGQLQGSL 340 Query: 337 NSAATVGKMFGPVVGGAIVDL 357 + ++ + GP++ AI Sbjct: 341 AALTSLTSIVGPLLFTAIYAA 361
>SECA#SecA protein signature. Length = 901 Score = 29.5 bits (66), Expect = 0.006 Identities = 12/37 (32%), Positives = 23/37 (62%) Query: 122 KNMKKFFNPGPDSIIEAGDMLVLSGARHEVKRIINEL 158 + +K + D+++EAG + ++ RHE +RI N+L Sbjct: 535 EKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQL 571
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 27.4 bits (60), Expect = 0.008 Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Query: 8 ESYITQAEQAVEYAKEQLDQGMRQEHYNTMEYSDAQLQLEQAYNDLQTMQQHANDEQREQ 67 E+ + QA + AKE LD+ +DA+ + E+A N L Q AN + Q Sbjct: 185 EAAVEQAGKEATEAKEALDKATDATV---KAGTDAKAKAEKADNILTKFQGTANAASQNQ 241 Query: 68 LNRAR 72 +++ Sbjct: 242 VSQGE 246
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 102 bits (256), Expect = 2e-27 Identities = 37/144 (25%), Positives = 70/144 (48%), Gaps = 5/144 (3%) Query: 1 MKRISILIADDEAEIADLIEIHLEKEGYHVVKAADGEEAIHIIETQPIDLVVLDIMMPKM 60 M +IL+ADD+A I ++ L + GY V ++ I DLVV D++MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGYEVTRQIRA-KHHMPIIFLSAKTSDFDKVTGLVLGADDYMTKPFTPIELVARVNAQLR 119 + +++ +I+ + +P++ +SA+ + + GA DY+ KPF EL+ + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII----G 116 Query: 120 RFLTLNQPKVAENKSALQVGGVTI 143 R L + + ++ + Q G + Sbjct: 117 RALAEPKRRPSKLEDDSQDGMPLV 140
>adhesinb#Adhesin B signature. Length = 310 Score = 27.9 bits (62), Expect = 0.044 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 4/49 (8%) Query: 1 MKKLLLTALISTSIFGLAACGGKDNDEK----KLVVGASNVPHAEILEK 45 MKK L+ + GLAAC + + + KL V A+N A+I + Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKN 49
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 57.5 bits (139), Expect = 6e-12 Identities = 23/134 (17%), Positives = 54/134 (40%), Gaps = 2/134 (1%) Query: 4 VLVIKNERSLAKKIVSGLTEEGHFILKLHNENEGLNIIYEQDWDIIILDWDSLSISGPEI 63 +LV ++ ++ + L+ G+ + N I D D+++ D + ++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 CRQIR-LVKMTPIIIVTDNISSKDCVAGLQAGADDYIRKPFAKEELVARV-QAILRRSGC 121 +I+ P+++++ + + + GA DY+ KPF EL+ + +A+ Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 122 NQQHETTFFQFKDL 135 + E L Sbjct: 126 PSKLEDDSQDGMPL 139
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 38.8 bits (90), Expect = 2e-07 Identities = 21/77 (27%), Positives = 43/77 (55%), Gaps = 4/77 (5%) Query: 1 MHTLLSVLLIIVSILMIVMVLMQSSNSSGLSGAISGGAE-QLFGKQKARGIEAVLNRITI 59 M+ L V+ +IV+I ++ ++++Q + + + GA LFG + G + R+T Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG---SSGSGNFMTRMTA 57 Query: 60 VLAVLFFALTIGVTYLN 76 +LA LFF +++ + +N Sbjct: 58 LLATLFFIISLVLGNIN 74
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 30.0 bits (67), Expect = 0.026 Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 1/44 (2%) Query: 210 GKDIGYMQITSFAENTAKEFKDQLKELEKKNIKGLVIDVRGNPG 253 GKDI F + T++ K+QL EL NI ++ ++ N Sbjct: 573 GKDITEFDFN-FDQQTSQNIKNQLAELNATNIYTVLDKIKLNAK 615
>SECA#SecA protein signature. Length = 901 Score = 1171 bits (3030), Expect = 0.0 Identities = 446/897 (49%), Positives = 598/897 (66%), Gaps = 65/897 (7%) Query: 1 MIGILKKVF-DVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVD 59 +I +L KVF N R ++RM+K V I+A+E ++ L+DE+LKGKT EF+ RL KGE ++ Sbjct: 2 LIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLE 61 Query: 60 DLLPEAFAVVREAATRVLGMRPYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNAL 119 +L+PEAFAVVREA+ RV GMR + VQL+GG+ L+E I+EM+TGEGKTLT+TLP YLNAL Sbjct: 62 NLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL 121 Query: 120 TGKGVHVVTVNEYLAQRDANEMGQLHEFLGLTVGINLNSMSREEKQEAYAADITYSTNNE 179 TGKGVHVVTVN+YLAQRDA L EFLGLTVGINL M K+EAYAADITY TNNE Sbjct: 122 TGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNE 181 Query: 180 LGFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANA 239 GFDYLRDNM E+ VQR LH+A++DEVDSIL+DEARTPLIISG A+ S+E+Y N Sbjct: 182 YGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNK 241 Query: 240 FVRTL-----------ENEKDYSFDVKTKNVMLTEDGITKAEKAFHI-------ENLFDL 281 + L + E +S D K++ V LTE G+ E+ E+L+ Sbjct: 242 IIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSP 301 Query: 282 KHVALLHHINQALRAHVVMHRDTDYVVQEGEIVIVDQFTGRLMKGRRYSEGLHQAIEAKE 341 ++ L+HH+ ALRAH + RD DY+V++GE++IVD+ TGR M+GRR+S+GLHQA+EAKE Sbjct: 302 ANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKE 361 Query: 342 GVEIQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIRD 401 GV+IQNE+ TLA+ITFQNYFR+YEKL+GMTGTA TE EF +IY ++ +V+PTN+P+IR Sbjct: 362 GVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRK 421 Query: 402 DRADLIFKSMKGKFNAVVEDIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNA 461 D DL++ + K A++EDI R +GQPVLVGT++IE SEL+S LT+ G++HN+LNA Sbjct: 422 DLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNA 481 Query: 462 KNHAREADIIAEAGMKGAVTIATNMAGRGTDIKLG------------------------- 496 K HA EA I+A+AG AVTIATNMAGRGTDI LG Sbjct: 482 KFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADW 541 Query: 497 ----DDIKNIG-LAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSMEDELMRRFGSD 551 D + G L +IGTERHESRRIDNQLRGR+GRQGD G ++FYLSMED LMR F SD Sbjct: 542 QVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASD 601 Query: 552 NMKAMMDRLGMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDDVLRQQREVIYK 611 + MM +LGM + IE V++A+ +AQ++VE N+D RKQLL+YDDV QR IY Sbjct: 602 RVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYS 661 Query: 612 QRQEVMESENLRGIIEGMMKSTVERAV-ALHTQEEIEEDWNIKGLVDYLNTNLLQEGDVK 670 QR E+++ ++ I + + + + A + +EE W+I GL + L + + + Sbjct: 662 QRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIA 721 Query: 671 E--EELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDTKWTEHIDA 728 E ++ L E + E I+A+ IE Y KE+++ E MR FEK V+ + +D+ W EH+ A Sbjct: 722 EWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAA 781 Query: 729 MDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEI---------- 778 MD+LR+GIHLR Y Q DP +EY+ E F+MF +M+ S++ E+ + K ++ Sbjct: 782 MDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELE 841 Query: 779 -EQNLERQEVVQGEAVHPSSDGEEAKKKPVVKGDQ--VGRNDLCKCGSGKKYKNCCG 832 ++ +E + + Q + + D A + + VGRND C CGSGKKYK C G Sbjct: 842 QQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHG 898
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 30.3 bits (68), Expect = 0.007 Identities = 53/243 (21%), Positives = 99/243 (40%), Gaps = 19/243 (7%) Query: 27 KQAYAGNLLGLLWVFLNPLSQIGVYWLVFGLGIRGGAPVHGVPYFVWLVCGLVTWFFVGT 86 K+A +LLG L PL I ++ L GLG+ G V GV Y +L G+V + Sbjct: 28 KKAALASLLGHL---AEPL--IYLFGLGAGLGVMVGR-VGGVSYTAFLAAGMVATSAMTA 81 Query: 87 TITQSANSIYSRLN---TVSKMNFPLSIIPTYVVISQLY--THLILIIFALVIVIFNLGF 141 ++ + + R+ T M + + V+ + T L + +V LG+ Sbjct: 82 ATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGY 141 Query: 142 STINILELMYGLVASTLFLIALSFLTSTLSTMLRDIQLLI--QS--VTRMLFFLTPIFWE 197 + L L+Y L L +A + L ++ + I Q+ +T +LF +F Sbjct: 142 TQ--WLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVF-- 197 Query: 198 PKENMSNLLLFIIKINPLYYIVEVYRGALIYNDTSIVLSWYTLYFWGAVIILFIAGSMLH 257 P + + + + PL + +++ R ++ + V VI F++ ++L Sbjct: 198 PVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLR 257 Query: 258 IRF 260 R Sbjct: 258 RRL 260
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 478 bits (1233), Expect = e-173 Identities = 179/330 (54%), Positives = 244/330 (73%), Gaps = 5/330 (1%) Query: 1 MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVAIDRNTG----KVLAVGEEARSMVGRTP 56 MF+ D+ IDLGTAN LI+VKG+GIVLNEPSVVAI ++ V AVG +A+ M+GRTP Sbjct: 8 MFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGRTP 67 Query: 57 GNIVAIRPLKDGVIADFEITEAMLKYFINKLDVKSFFS-KPRILICCPTNITSVEQKAIR 115 GNI AIRP+KDGVIADF +TE ML++FI ++ SF PR+L+C P T VE++AIR Sbjct: 68 GNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIR 127 Query: 116 EAAERSGGKTVFLEEEPKVAAVGAGMEIFQPSGNMVVDIGGGTTDIAVLSMGDIVTSSSI 175 E+A+ +G + VFL EEP AA+GAG+ + + +G+MVVDIGGGTT++AV+S+ +V SSS+ Sbjct: 128 ESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSV 187 Query: 176 KMAGDKFDMEILNYIKRKYKLLIGERTSEDIKIKVGTVFPGARSEELEIRGRDMVTGLPR 235 ++ GD+FD I+NY++R Y LIGE T+E IK ++G+ +PG E+E+RGR++ G+PR Sbjct: 188 RIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPR 247 Query: 236 TITVCSEEITEALKENAAVIVQAAKGVLERTPPELSADIIDRGVILTGGGALLHGIDMLL 295 T+ S EI EAL+E IV A LE+ PPEL++DI +RG++LTGGGALL +D LL Sbjct: 248 GFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLL 307 Query: 296 AEELKVPVLIAENPMHCVAVGTGIMLENID 325 EE +PV++AE+P+ CVA G G LE ID Sbjct: 308 MEETGIPVVVAEDPLTCVARGGGKALEMID 337
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.7 bits (87), Expect = 6e-05 Identities = 22/121 (18%), Positives = 42/121 (34%), Gaps = 6/121 (4%) Query: 51 KNDDMTIEEAKRRAAAAAKA--KAAALAKQKREGIEEVTEEEKVKAKAAAAAKAKAAALA 108 + + E +K+ + K A Q RE +E K + A++ + Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKE 1094 Query: 109 KQK--ASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGKKEEELKQEEPSV-NEPYL 165 Q + +EKAK + ++ + + E Q EP+ N+P + Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVT-SQVSPKQEQSETVQPQAEPARENDPTV 1153 Query: 166 N 166 N Sbjct: 1154 N 1154 Score = 36.2 bits (83), Expect = 2e-04 Identities = 27/156 (17%), Positives = 47/156 (30%), Gaps = 11/156 (7%) Query: 7 DLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKA--LPKNDDMTIEEAKRRA 64 DL + + E + + ++ + N E + P ++ Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038 Query: 65 AAAAKAKAAALAKQKREGIEEVTEEEKVKAKAAAAAKAKAAALAKQKASQGNGDSGDEKA 124 A +K + +K E ++ TE + A AK+ A + +G E Sbjct: 1039 TVAENSKQESKTVEKNE--QDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQ 1096 Query: 125 KAIAAAKAKAAAAARAKTKGAEGKKEEELKQEEPSV 160 A +AK E E QE P V Sbjct: 1097 TTETKETATVEKEEKAKV-------ETEKTQEVPKV 1125 Score = 34.7 bits (79), Expect = 6e-04 Identities = 26/154 (16%), Positives = 48/154 (31%), Gaps = 17/154 (11%) Query: 14 EAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEAKRRAAAAAKAKAA 73 +A + E A+ K E EKE+ + T E K + + K + + Sbjct: 1077 KANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQS 1136 Query: 74 ALAKQKREGIEEVTEEEKVKAKAAAAAKAKAAALAKQKASQGNGDSGDEKAKAIAAAKAK 133 E V+ +A A + K+ SQ N + E+ ++ + Sbjct: 1137 ----------------ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVE 1180 Query: 134 AAAAARAKTKGAEGKKEEELKQEEPSVNEPYLNQ 167 T E + P+ +P +N Sbjct: 1181 QPVTEST-TVNTGNSVVENPENTTPATTQPTVNS 1213 Score = 33.1 bits (75), Expect = 0.002 Identities = 19/152 (12%), Positives = 46/152 (30%), Gaps = 3/152 (1%) Query: 13 REAARR-AKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEAKRRAAAAAKAK 71 +E KE A K VE K +E + + PK + E + +A A + Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQS--ETVQPQAEPAREND 1150 Query: 72 AAALAKQKREGIEEVTEEEKVKAKAAAAAKAKAAALAKQKASQGNGDSGDEKAKAIAAAK 131 K+ + + E+ + ++ + ++ + A Sbjct: 1151 PTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPT 1210 Query: 132 AKAAAAARAKTKGAEGKKEEELKQEEPSVNEP 163 + ++ + K + + E + + Sbjct: 1211 VNSESSNKPKNRHRRSVRSVPHNVEPATTSSN 1242
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.0 bits (67), Expect = 0.005 Identities = 23/116 (19%), Positives = 49/116 (42%), Gaps = 6/116 (5%) Query: 36 PLMGIMKEREEHVANEIDAAERNNAEAKKLVEEQREMLKQSRVEAQELIERAKKQAVDQK 95 P E E VA + +++ + +K ++ E Q+R A+E ++ +A Q Sbjct: 1028 PAPATPSETTETVA---ENSKQESKTVEKNEQDATETTAQNREVAKE--AKSNVKANTQT 1082 Query: 96 DVIVAAAKEEAESIKASAVQEIQREKEQAIAALQEQVASLSVQIASKVIEKELKEE 151 + + + E E+ + EKE+ E+ + ++ S+V K+ + E Sbjct: 1083 NEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVP-KVTSQVSPKQEQSE 1137
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.0 bits (93), Expect = 1e-05 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 5/99 (5%) Query: 177 AESPEEEQVKQIDDEEVVDTEEKKEDEVKEKKVVKQEVATKVTASEKKVVKNETKVEEQP 236 A E + + ++ T EK E + E +EVA + K VK T+ E Sbjct: 1031 ATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKE----AKSNVKANTQTNEVA 1086 Query: 237 VSKEETKTVEKVEKPVEQKQEKQNEY-VKVEEEEEEPEV 274 S ETK + E EK+ + V+ E+ +E P+V Sbjct: 1087 QSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Score = 33.1 bits (75), Expect = 0.001 Identities = 24/119 (20%), Positives = 44/119 (36%), Gaps = 6/119 (5%) Query: 166 TAVRKEEHVVKAESPEEEQVKQIDDEEVVDTEEKKEDEVKEKKVVKQEVATKVTASEKKV 225 + ++ + V K E E Q V E K + + + ++ ++ Sbjct: 1043 NSKQESKTVEKNEQDATETTAQ---NREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 226 VKNETKVEEQPVSKEETKTVEKVEKPVEQ---KQEKQNEYVKVEEEEEEPEVKLFIVEA 281 K VE++ +K ET+ ++V K Q KQE+ E E + + I E Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Score = 29.3 bits (65), Expect = 0.020 Identities = 20/103 (19%), Positives = 39/103 (37%), Gaps = 5/103 (4%) Query: 176 KAESPEEEQVKQIDDEEVVDTEEKKEDEVKEKKVV----KQEVATKVTASEKKVVKNETK 231 K+ Q ++ +T+E + E KE V K +V T+ T KV + Sbjct: 1073 KSNVKANTQTNEVAQSGS-ETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSP 1131 Query: 232 VEEQPVSKEETKTVEKVEKPVEQKQEKQNEYVKVEEEEEEPEV 274 +EQ + + + P +E Q++ + E+ + Sbjct: 1132 KQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKE 1174
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 112 bits (281), Expect = 2e-32 Identities = 31/117 (26%), Positives = 56/117 (47%) Query: 3 GKILIVDDQYGIRVLLHEVFQKEGYQTFQAANGFQALDIVKKDNPDLVVLDMKIPGMDGI 62 IL+ DD IR +L++ + GY +N + + DLVV D+ +P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 EILKHVKEIDESIKVILMTAYGELDMIQEAKDLGALMHFAKPFDIDEIRQAVRNELA 119 ++L +K+ + V++M+A +A + GA + KPFD+ E+ + LA Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.0 bits (158), Expect = 4e-15 Identities = 27/141 (19%), Positives = 61/141 (43%), Gaps = 6/141 (4%) Query: 19 RREQMIKGAVQLFKQKGFPRTTTREIAKAAGFSIGTLYEYIRTKDDVLYLVCDSIYEHVK 78 R+ ++ A++LF Q+G T+ EIAKAAG + G +Y + + K D+ + + ++ Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 79 ERLEEV-VCTEKGSVESLKIAITNYFKVMDELQEE---VLIMYQEVRFLPKESLPYVLEK 134 E E + L+ + + + + + I++ + F+ + ++ ++ Sbjct: 72 ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQR 131 Query: 135 EF--QMVGMFENILEQCTENG 153 + E L+ C E Sbjct: 132 NLCLESYDRIEQTLKHCIEAK 152
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.9 bits (127), Expect = 3e-10 Identities = 21/137 (15%), Positives = 49/137 (35%), Gaps = 12/137 (8%) Query: 2 KILLIMEEAEERRSLAEKFIENIKNVECFEASMGTEALFIMKKHTPDFVFLNSKLMDGTG 61 IL+ ++A R L + + + S + D V + + D Sbjct: 5 TILVADDDAAIRTVLNQAL--SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 FEYVNLLREVNCYAKFIFMGE--DIEESITAFRFQAFYYLLRPFREEDLQFLLYRMGKEQ 119 F+ + +++ + M +I A A+ YL +PF +L ++ Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII------- 115 Query: 120 GEKAKSYLRKLPIEGQE 136 +A + ++ P + ++ Sbjct: 116 -GRALAEPKRRPSKLED 131
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 59.1 bits (143), Expect = 8e-12 Identities = 72/380 (18%), Positives = 142/380 (37%), Gaps = 35/380 (9%) Query: 7 ISKRKLLGIAGLGWLFDAMDVGMLSFVMVALQKDWGLSTQEMGWIG---SINSIGMAVGA 63 + + L + DA+ +G++ V+ L +D S G ++ ++ A Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 64 LVFGILSDKIGRKSVFIITLLLFSIGSGLTALTTTLAMFLVLRFLIGMGLGGELPVASTL 123 V G LSD+ GR+ V +++L ++ + A L + + R + G+ G VA Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAY 119 Query: 124 VSESVEAHERGKIVVLLESFWAGGWLIAALISYF---VIPKYGWEVAMILSAIPALYALY 180 +++ + ER + + + + G + ++ P + A L+ + L + Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCF 179 Query: 181 LRWNLPDSPRFQKVEKRPSVIENIKSVWSGEYRKATIMLWILWFSV---------VFSYY 231 L LP+S + ++ R + + S L ++F + ++ + Sbjct: 180 L---LPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIF 236 Query: 232 GM--FLWLPSV--MVLKGFSLIKSFQYVLIMTLAQLPGYFTAAWFIERLGRKFVLVTYLI 287 G F W + + L F ++ S +I RLG + L+ +I Sbjct: 237 GEDRFHWDATTIGISLAAFGILHSLAQAMITGP-----------VAARLGERRALMLGMI 285 Query: 288 GTACSAYLFGVAESLTVLIVAGMLLSFFNLGAWGALYAYTPEQYPTVIRGTGAGMAAAFG 347 L A + +LL+ +G AL A Q +G G AA Sbjct: 286 ADGTGYILLAFATRGWMAFPIMVLLASGGIGM-PALQAMLSRQVDEERQGQLQGSLAALT 344 Query: 348 RIGGILGPLLVGYLVASQAS 367 + I+GPLL + A+ + Sbjct: 345 SLTSIVGPLLFTAIYAASIT 364 Score = 33.6 bits (77), Expect = 0.001 Identities = 29/125 (23%), Positives = 45/125 (36%), Gaps = 5/125 (4%) Query: 274 ERLGRKFVLVTYLIGTACSAYLFGVAESLTVLIVAGMLLSFFNLGAWGALYAYTPEQYPT 333 +R GR+ VL+ L G A + A L VL + G +++ AY + Sbjct: 68 DRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYI-GRIVAGITGATGAVAGAYIADITDG 126 Query: 334 VIRGTGAG-MAAAFGRIGGILGPLLVGYLVASQASLSLIFTIFCGSILIGVFAVIILGQE 392 R G M+A FG G + GP+L G + + L E Sbjct: 127 DERARHFGFMSACFG-FGMVAGPVLGGLMGGFSPHAPFFAAAALN--GLNFLTGCFLLPE 183 Query: 393 TKQRE 397 + + E Sbjct: 184 SHKGE 188
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.4 bits (81), Expect = 5e-04 Identities = 9/47 (19%), Positives = 18/47 (38%) Query: 289 EQEQSAKKEEKKKEEAKEHKPPVTQQEKEKEKEKEKVAEKKEETQAL 335 Q + K E + + E EK + + A+ + ++Q L Sbjct: 261 RQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVL 307 Score = 32.3 bits (73), Expect = 0.004 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 9/63 (14%) Query: 291 EQSAKKEEKKKEEAKE-----HKPPVTQQEKEKEKEKEKVAEKKEETQALIFSGRQLFEQ 345 ++ K+ EK EEA K +E +K EKEK AE + + +A + L E+ Sbjct: 392 REAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEK-AELQAKLEA---EAKALKEK 447 Query: 346 MYK 348 + K Sbjct: 448 LAK 450
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 36.3 bits (84), Expect = 4e-04 Identities = 38/179 (21%), Positives = 57/179 (31%), Gaps = 41/179 (22%) Query: 185 RKFAEVGARIPKGVLLVGPPGTGKTLLARAV---AGEAGVPFFS-----ISGSDFVEMFV 236 + + +++ G GTGK L+ARA+ PF + I Sbjct: 150 YRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELF 209 Query: 237 GV------GASRVRD-LFENAKKNAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQLL 289 G GA FE A+ +F+DEI + L + Sbjct: 210 GHEKGAFTGAQTRSTGRFEQAEGGT---LFLDEIGDMPMDAQTRLLRVLQQG-------- 258 Query: 290 VEMDGFGANEGII----IIAATNRPDILDPALLRPGRFDRQITVDRPDVNGREAVLKVH 344 E G I I+AATN+ L + G F R D+ R V+ + Sbjct: 259 -EYTTVGGRTPIRSDVRIVAATNKD--L-KQSINQGLF-------REDLYYRLNVVPLR 306
>PF03309#Bvg accessory factor Length = 271 Score = 379 bits (975), Expect = e-136 Identities = 96/269 (35%), Positives = 163/269 (60%), Gaps = 12/269 (4%) Query: 1 MIFVLDVGNTNAVLGVF----EEGELRQHWRMETDRHKTEDEYGMLVKQLLEHEGLSFED 56 M+ +DV NT+ V+G+ + ++ Q WR+ T+ T DE + + L+ G E Sbjct: 1 MLLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDGLI---GDDAER 57 Query: 57 VKGIIVSSVVPPIMFALERMCEKYFKIKP-LVVGPGIKTGLNIKYENPREVGADRIVNAV 115 + G S VP ++ + M E+Y+ P +++ PG++TG+ + +NP+EVGADRIVN + Sbjct: 58 LTGASGLSTVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCL 117 Query: 116 AGIHLYGSPLIIVDFGTATTYCYINEEKHYMGGVITPGIMISAEALYSRAAKLPRIEITK 175 A H YG+ I+VDFG++ ++ + ++GG I PG+ +S++A +R+A L R+E+T+ Sbjct: 118 AAYHKYGTAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELTR 177 Query: 176 PSSVVGKNTVSAMQSGILYGYVGQVEGIVKRMKEEA----KQEPKVIATGGLAKLISEES 231 P SV+GKNTV MQ+G ++G+ G V+G+V R++++ + V+ATG A L+ + Sbjct: 178 PRSVIGKNTVECMQAGAVFGFAGLVDGLVNRIRDDVDGFSGADVAVVATGHTAPLVLPDL 237 Query: 232 NVIDVVDPFLTLKGLYMLYERNANLQHEK 260 ++ D LTL GL +++ERN Q K Sbjct: 238 RTVEHYDRHLTLDGLRLVFERNRANQRGK 266
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.4 bits (63), Expect = 0.045 Identities = 19/94 (20%), Positives = 42/94 (44%), Gaps = 21/94 (22%) Query: 191 ILYTPSLETGILNGITRAFIIKVAEELGIKVKEGFFTKDELLSADEVFVTNSIQEIVPLN 250 IL P G + + +++ A+ELGI+V+ + K+ +VF + ++++ L Sbjct: 50 ILLIPKDYKGQGSSLND--LVRTADELGIEVQ--YDEKNGTAITKQVF--GTAEKLIGL- 102 Query: 251 RIEERDFPGKVGMVTKRFINLYEMQREKLWSRNE 284 T+R + ++ Q +KL + + Sbjct: 103 --------------TERGVTIFAPQLDKLLQKYQ 122
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 29.4 bits (66), Expect = 0.015 Identities = 10/72 (13%), Positives = 26/72 (36%), Gaps = 4/72 (5%) Query: 146 ILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRN 205 L + + +L+ + + + G R I +++ L+ +R+ Sbjct: 145 ALKGRPELAHLSHLVEQALVSMAEEQGETIVLGAR----ITPEAYRESQSGVNPLQPLRD 200 Query: 206 LEQLNVLGYPVL 217 + V+GY + Sbjct: 201 TYRDAVMGYQGI 212
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.005 Identities = 8/25 (32%), Positives = 12/25 (48%) Query: 25 VRAQDVIILEGDLGAGKTTFTKGLA 49 + ++LEG G GK+T L Sbjct: 593 CKFDYSVVLEGTGGIGKSTLINTLV 617
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.2 bits (104), Expect = 2e-08 Identities = 21/72 (29%), Positives = 32/72 (44%) Query: 67 ITNIAILPEYRGLKLGDALLKEVISEAKTLGVKTMTLEVRVSNEVAKQLYRKYGFQNGGI 126 I +IA+ +YR +G ALL + I AK + LE + N A Y K+ F G + Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAV 151 Query: 127 RKRYYADNQEDG 138 Y++ Sbjct: 152 DTMLYSNFPTAN 163
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.024 Identities = 13/44 (29%), Positives = 18/44 (40%), Gaps = 2/44 (4%) Query: 379 LVGPNGIGKSTLLKSIVNKLPLLHGDVSFGSNVSVGYYDQEQAN 422 L G GIGKSTL+ ++V G+ Y+Q Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD--SYEQIAGI 642
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.008 Identities = 11/27 (40%), Positives = 14/27 (51%) Query: 35 VGGNGIGKSTLLRILTGELIHDDGNIE 61 G GIGKSTL+ L G D + + Sbjct: 602 EGTGGIGKSTLINTLVGLDFFSDTHFD 628
>cloacin#Cloacin signature. Length = 551 Score = 25.4 bits (55), Expect = 0.025 Identities = 13/29 (44%), Positives = 16/29 (55%) Query: 54 DSSHGGSHDCGGSFGGDSGGSCDGGGGGG 82 S G H GGS G+ GG+ + GGG G Sbjct: 48 GGSGSGIHWGGGSGHGNGGGNGNSGGGSG 76
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 83.5 bits (206), Expect = 3e-22 Identities = 46/198 (23%), Positives = 83/198 (41%), Gaps = 8/198 (4%) Query: 1 MRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVK 60 ++ A+E ++ I A LFSQ+G ++TS+ EI + ++G+IY+HFK K +LF + + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 QHTYDWLEKWNEK-EKLYSTSTEKLYALAEYHVEDIQQPISN----AIEEFSMSQVVSKE 115 + E E K L + + +E I V Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 116 ILDEMLALT-RESYVMFETLIEAGIQSGEFRED-NTRDLMYIVNGLLSGL-GVLYYELDY 172 ++ + ESY E ++ I++ D TR I+ G +SGL + Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQS 184 Query: 173 KELKRIYKKAIDVLLKGM 190 +LK+ + + +LL+ Sbjct: 185 FDLKKEARDYVAILLEMY 202
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 27/130 (20%), Positives = 50/130 (38%), Gaps = 5/130 (3%) Query: 34 FIMERTNNDPVSVSL-LSVMEYAPIFIFSFIGGALADRWNPKRTMVAGDVLSVLSIIGIV 92 F +R + D ++ + L+ + I G +A R +R ++ G + I + Sbjct: 236 FGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI--L 293 Query: 93 LLLKLDYWQAIFFATLISAIVGQFSQPSSSRIFKRYVKEEQVANAIAFNQTLQSLFMIFG 152 L W + F ++ G P+ + R V EE+ L SL I G Sbjct: 294 LAFATRGW--MAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVG 351 Query: 153 PVVGSLVYTQ 162 P++ + +Y Sbjct: 352 PLLFTAIYAA 361 Score = 35.2 bits (81), Expect = 4e-04 Identities = 60/344 (17%), Positives = 124/344 (36%), Gaps = 26/344 (7%) Query: 58 FIFSFIGGALADRWNPKRTMVAGDVLSVLS--IIGIVLLLKLDYWQAIFFATLISAIVGQ 115 F + + GAL+DR+ + ++ + + I+ L + ++ +++ I G Sbjct: 57 FACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWV-----LYIGRIVAGITGA 111 Query: 116 FSQPSSSRIFKRYVKEEQVANAIAFNQTLQSLFMIFGPVVGSL---VYTQLGLFTSLYSL 172 + + ++ A F M+ GPV+G L F + Sbjct: 112 -TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALN 170 Query: 173 IILFLLSAIALSFLPKWVEQEQVARDSLKNDIKEGWKYVLHTKNLRMITITFTIMGLAVG 232 + FL LP+ + E+ + +++ + + F IM L Sbjct: 171 GLNFLTGCF---LLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQ 227 Query: 233 LTNPLEVFLVIERLGMEKEAVQYLAAADGI-GMLIGGIVAAVFASKVNPKKMFVFGMSIL 291 + L V +R + + AA GI L ++ A+++ ++ + GM Sbjct: 228 VPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIAD 287 Query: 292 AMSFLVEGLSTSFWITSFMRFGTGICLACVNI---VVGTLMIQLVPENMVGRVNGTILPL 348 +++ +T W M F + LA I + ++ + V E G++ G++ L Sbjct: 288 GTGYILLAFATRGW----MAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAAL 343 Query: 349 FMGAMLIGTALAGGLKEMTSLV---IVFCIAMALILLAIGPVLR 389 ++G L + + + AL LL + P LR Sbjct: 344 TSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCL-PALR 386
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 46.4 bits (110), Expect = 1e-07 Identities = 30/158 (18%), Positives = 56/158 (35%), Gaps = 3/158 (1%) Query: 264 DLGISATNLLIILFVTQIVACPFALLYGKLSTTFTGKKMLYVGIIIYIIICIYAYFLKTT 323 D + + + +YGKLS K++L GIII + + + Sbjct: 43 DFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF 102 Query: 324 LDFWILAMLV-ATSQGGIQALSRSYFAKLVPKESANEFFGFYNIFGKFAAIMGPVLVGVT 382 I+A + AL A+ +PKE+ + FG +GP + G+ Sbjct: 103 FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMI 162 Query: 383 TQLTGKTNAGVLSIIVLFIIGGFLLTRVPENNTSVTPP 420 + +L I ++ II L ++ + + Sbjct: 163 AHYIHWSY--LLLIPMITIITVPFLMKLLKKEVRIKGH 198
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 45.4 bits (107), Expect = 1e-06 Identities = 43/214 (20%), Positives = 78/214 (36%), Gaps = 18/214 (8%) Query: 833 TQNIVAKEEPKEPVEEVEGSKEEPIKEAEGSKEEPKEPAKEVEGSKEEPKEPAKEVEGSK 892 T N + + P P E ++ + EA P P++ E E K+ +K VE ++ Sbjct: 999 TPNNIQADVPSVPSNNEEIAR---VDEAPVPPPAPATPSETTETVAENSKQESKTVEKNE 1055 Query: 893 EEVKEPAKEVEGPKEEVKEPTK------EVEGPKEEVKEPTKEVEGPKEEVKEPMKEVEG 946 ++ E + +E K K EV E KE V++ K Sbjct: 1056 QDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVE 1115 Query: 947 SKEEVKGPTKEAEGSKEEVK--------EPTTEVEGSKEVKEPGKEVEGSKDAINQSAVA 998 +++ + P ++ S ++ + EP E + + +KEP + + Q A Sbjct: 1116 TEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQ-TNTTADTEQPAKE 1174 Query: 999 QETNVNNQVGKEKVVENQNMKENKPAVTKQEESK 1032 +NV V + V N P T ++ Sbjct: 1175 TSSNVEQPVTESTTVNTGNSVVENPENTTPATTQ 1208 Score = 41.6 bits (97), Expect = 2e-05 Identities = 31/189 (16%), Positives = 59/189 (31%), Gaps = 8/189 (4%) Query: 860 AEGSKEEPKEPAKEVEGSKEEPKEPAKEVEGSKEEVKEPAKEVEGPKEEVKEPTKEVEGP 919 + S E E P P++ E E K+ +K VE +++ E T + Sbjct: 1009 SVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREV 1068 Query: 920 KEEVKEPTKEVEGPKEEVKEPMKEVEGSKEEVKGPTKEAEGSKEEVKEPTTEVEGSKEVK 979 +E K K E + + E E K + K +V+ T+ + Sbjct: 1069 AKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQ 1128 Query: 980 EPGKEVEGSKDAINQSAVAQETNVNNQVGKEKVVENQ------NMKENKPAVTKQEESKK 1033 K+ + + + A N KE + + + +Q ++ Sbjct: 1129 VSPKQEQ--SETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTES 1186 Query: 1034 SLGATGGQE 1042 + TG Sbjct: 1187 TTVNTGNSV 1195 Score = 39.7 bits (92), Expect = 9e-05 Identities = 38/191 (19%), Positives = 65/191 (34%), Gaps = 12/191 (6%) Query: 859 EAEGSKEEPKEPAKEVEGSKEEPKEPAKEVEGSKEEVKEPAKEVEGPKEEVKEPTKEVEG 918 E S E KE E KE A + K +V E K E PK + K+ + Sbjct: 1084 EVAQSGSETKETQ------TTETKETATVEKEEKAKV-ETEKTQEVPKVTSQVSPKQEQS 1136 Query: 919 PKEEVKEPTKEVEGPKEEVKEPMKEVEGSKEEVKGPTKEAEGSKEEVKEPTTEVEGSKEV 978 + + P +KEP + + + + + + ++ V E TT G+ V Sbjct: 1137 ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVV 1196 Query: 979 KEPGKEVEGSKDAINQSAVAQETNVNNQVGKEKVVENQNMKENKPAVTKQEESKKSLGAT 1038 + P + S + + ++ V N +PA T + Sbjct: 1197 ENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNV-----EPATTSSNDRSTVALCD 1251 Query: 1039 GGQENTSTLLS 1049 NT+ +LS Sbjct: 1252 LTSTNTNAVLS 1262 Score = 38.9 bits (90), Expect = 1e-04 Identities = 31/171 (18%), Positives = 51/171 (29%), Gaps = 8/171 (4%) Query: 833 TQNIVAKEEPKEPVEEVEGSKEEPIKEAEGSKEEPKEPAKEVEGSKEEPKEPAKEVEGSK 892 TQ KE VE+ E +K E K E K + K+ + +P+ Sbjct: 1095 TQTTETKETAT--VEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPT 1152 Query: 893 EEVKEPAKEVEGPKEEVKEPTKEVEGPKEEVKEPTKEVEGPKEEVKEPMKEVEGSKEEVK 952 +KEP + + + + ++ V E T G E + Sbjct: 1153 VNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENP-----ENTTPATT 1207 Query: 953 GPTKEAEGSKEEVKEPTTEVEGSKEVKEPGKEVEGSKDAINQS-AVAQETN 1002 PT +E S + V EP + + + TN Sbjct: 1208 QPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTN 1258 Score = 35.8 bits (82), Expect = 0.001 Identities = 37/195 (18%), Positives = 69/195 (35%), Gaps = 16/195 (8%) Query: 856 PIKEAEGSKEEPKEPAKEVEGSKEEPKEPAKEVEGSKEE--------VKEPAKEVEGPKE 907 P E + + P P+ E ++ + P++ E E Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 908 EVKEPTKEVEGPKEEVKEPTKEVEGPKEEVKEPMKEVEGSKEEVKGPTKEAEGSKEEVKE 967 K+ +K VE +++ E T + +E K +K + E + ++ E E KE Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 968 PTTEVEGSKEVKEPGKEVEGSKDAINQSAVAQETNVNNQVGKEKVVENQNMKENKPAVT- 1026 T + K E K E K V + + + + + + +EN P V Sbjct: 1103 TATVEKEEKAKVETEKTQEVPK-------VTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 1027 KQEESKKSLGATGGQ 1041 K+ +S+ + A Q Sbjct: 1156 KEPQSQTNTTADTEQ 1170
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.4 bits (89), Expect = 1e-05 Identities = 25/101 (24%), Positives = 41/101 (40%), Gaps = 5/101 (4%) Query: 178 TYYEGNEIIGRLSDTNK-LFVSMKNEKLEGYVYVEVNPEFQE-ANIEFIATAENSRRKGV 235 Y + + + + + K F+ G + ++ + A IE IA A++ R+KGV Sbjct: 49 QYEDDDMDVSYVEEEGKAAFLYYLENNCIGRI--KIRSNWNGYALIEDIAVAKDYRKKGV 106 Query: 236 GERLLQAAIQYIFSFQGMREIELCLNTNNDRAVKLYKKVGF 276 G LL AI++ + L N A Y K F Sbjct: 107 GTALLHKAIEWAKE-NHFCGLMLETQDINISACHFYAKHHF 146
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 755 bits (1950), Expect = 0.0 Identities = 412/886 (46%), Positives = 569/886 (64%), Gaps = 16/886 (1%) Query: 94 YSMADLNKMNNQELVETLGSIKWHQITDLFQFNEDAKAFYKDKGKMQVVIDELAHRGSTF 153 Y+ +LN+MN +LVE + +I + + DLF FN+ + F+ ++ ++Q +I L G T+ Sbjct: 93 YTFDELNRMNYSDLVELIKTISYENVPDLFNFNDGSYTFFSNRDRVQAIIYGLEDSGRTY 152 Query: 154 TKDDSKGIQTFTEVLRSAFYLAFYNNELSELNERSFQDKCLPALKAIAKNPNFKLGTTEQ 213 T DD KGI T E LR+ +YL FYN +LS LN +++CLPA+KAI N NF+LGT Q Sbjct: 153 TADDDKGIPTLVEFLRAGYYLGFYNKQLSYLNTPQLKNECLPAMKAIQYNSNFRLGTKAQ 212 Query: 214 DTVVSAYGKLISNASSDVETVQYASNILKQYNDNFTTYVNDRMKGQAIYDIMQGIDYDIQ 273 D VV A G+LI NAS+D E + +L + DN Y ++ KG A++++M+GIDY Sbjct: 213 DGVVEALGRLIGNASADPEVINNCIYVLSDFKDNIDKYGSNYSKGNAVFNLMKGIDYYTN 272 Query: 274 SYLIEARKE-ANETMWYGKVDGFINEINRIALL-NEVTQENKWLVNNGIYFASRLGKFHS 331 S + + A T +Y ++D ++ + + + +++ +N WLVNN +Y+ R+GKF Sbjct: 273 SVIYNTKGYDAKNTEFYNRIDPYMERLESLCTIGDKLNNDNAWLVNNALYYTGRMGKFRE 332 Query: 332 NPNKGLEVVTQAMHMYPRLSEPYFVAVEQITTNYNGKDYSGNTVDLEKIRKEGKEQYLPK 391 +P+ + +AM YP LS Y A + N+ GK+ SGN +D KI+ + +E+YLPK Sbjct: 333 DPSISQRALERAMKEYPYLSYQYIEAANDLDLNFGGKNSSGNDIDFNKIKADAREKYLPK 392 Query: 392 TYTFDDGSIVFKTGDKVSEEKIKRLYWAAKEVKAQYHRVIGNDKALEPGNADDILTIVIY 451 TYTFDDG V K GDKV+EEKIKRLYWA+KEVKAQ+ RV+ NDKALE GN DDILT+VIY Sbjct: 393 TYTFDDGKFVVKAGDKVTEEKIKRLYWASKEVKAQFMRVVQNDKALEEGNPDDILTVVIY 452 Query: 452 NSPEEYQLNRQLYGYETNNGGIYIEETGTFFTYERTPEQSIYSLEELFRHEFTHYLQGRY 511 NSPEEY+LNR + G+ T+NGGIYIE GTFFTYERTPE+SIY+LEELFRHEFTHYLQGRY Sbjct: 453 NSPEEYKLNRIINGFSTDNGGIYIENIGTFFTYERTPEESIYTLEELFRHEFTHYLQGRY 512 Query: 512 EVPGLFGRGDMYQNERLTWFQEGNAEFFAGSTRTNNVVPRKSIISGLSSDPASRYTAERT 571 VPG++G+G+ YQ LTW++EG AEFFAGSTRT+ + PRKS+ GL+ D +R + Sbjct: 513 VVPGMWGQGEFYQEGVLTWYEEGTAEFFAGSTRTDGIKPRKSVTQGLAYDRNNRMSLYGV 572 Query: 572 LFAKYGSWDFYNYSFALQSYLYTHQFETFDKIQDLIRANDVKNYDAYRENLSKDLKLNEE 631 L AKYGSWDFYNY FAL +Y+Y + F+K+ + I+ NDV Y Y ++S D LN++ Sbjct: 573 LHAKYGSWDFYNYGFALSNYMYNNNMGMFNKMTNYIKNNDVSGYKDYIASMSSDYGLNDK 632 Query: 632 YQEYMQHLIDNQDKYNVPEVADDYLAEHTPKSLTAVEKEITETLPMKDAKMTKHSSQFFN 691 YQ+YM L++N D +VP V+D+Y+ H K + + +I E +KD SQFF Sbjct: 633 YQDYMDSLLNNIDNLDVPLVSDEYVNGHEAKDINEITNDIKEVSNIKDLSSNVEKSQFFT 692 Query: 692 TFTLEGTYTGSVTKGDSEDWNAMSKKVNEALEQLAQKEWSGYKTVTAYFVNYGVNSSNQF 751 T+ + GTY G ++G+ DW M+ K+N+ L++L++K W+GYKTVTAYFVN+ V+ + + Sbjct: 693 TYDMRGTYVGGRSQGEENDWKDMNSKLNDILKELSKKSWNGYKTVTAYFVNHKVDGNGNY 752 Query: 752 EYDVVFHG----IAKDDEENKAPTVNINGPYNGLVKEGIQFKSDGSKDEDGKIVSYLWDF 807 YDVVFHG D NK P I + +V+E I F SKDEDG+I +Y WDF Sbjct: 753 VYDVVFHGMNTDTNTDVHVNKEPKAVIKSDSSVIVEEEINFDGTESKDEDGEIKAYEWDF 812 Query: 808 GDGSTSAEVNPVHVYESEGSYKVALIVKDDKGKESKSEITVTV----KGGSLTESEPNNR 863 GDG S E H Y G Y+V L V D+ G + + V + ESEPNN Sbjct: 813 GDGEKSNEAKATHKYNKTGEYEVKLTVTDNNGGINTESKKIKVVEDKPVEVINESEPNND 872 Query: 864 PEEANRIG-LNTTIKGSLIGGDHTDVYTFNVASAKNIDISVLNEYGIGMTWVLHHESDMQ 922 E+AN+I N +KG+L D++D Y F+VA N+ I++ N +G+TW L+ E D+ Sbjct: 873 FEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKGNVKITLNNLNSVGITWTLYKEGDLN 932 Query: 923 NYAAYGQANGNHI---EANFNAKPGKYYLYVYKYDNGDGTYELSVK 965 NY Y A GN + +PG+YYL VY YDN GTY ++VK Sbjct: 933 NYVLY--ATGNDGTVLKGEKTLEPGRYYLSVYTYDNQSGTYTVNVK 976 Score = 97.9 bits (243), Expect = 8e-23 Identities = 60/251 (23%), Positives = 99/251 (39%), Gaps = 49/251 (19%) Query: 762 KDDEENKAPTVNINGPYNGLVKEGIQFKSD----GSKDEDGKIVSYLWDF---------- 807 K E+ +N + P N K KS+ G+ E+ Y +D Sbjct: 854 KVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKGNVKITL 913 Query: 808 ---------------GDGST-SAEVNPVHVYESEGSYKVA-----LIVKDDKGKESKSEI 846 GD + +G + L V + Sbjct: 914 NNLNSVGITWTLYKEGDLNNYVLYATGNDGTVLKGEKTLEPGRYYLSVYTYDNQ--SGTY 971 Query: 847 TVTVKGG-----------SLTESEPNNRPEEANRIGLNTTIKGSLIGGDHTDVYTFNVAS 895 TV VKG ++ E E NN ++A ++ N+ I G+L D D+Y+ ++ + Sbjct: 972 TVNVKGNLKNEVKETAKDAIKEVENNNDFDKAMKVDSNSKIVGTLSNDDLKDIYSIDIQN 1031 Query: 896 AKNIDISVLNEYGIGMTWVLHHESDMQNYAAYGQANGNHIEANFNAKPGKYYLYVYKYDN 955 +++I V N I M W+L+ D+ NY Y A+GN + PGKYYL VY+++N Sbjct: 1032 PSDLNIVVENLDNIKMNWLLYSADDLSNYVDYANADGNKLSNTCKLNPGKYYLCVYQFEN 1091 Query: 956 -GDGTYELSVK 965 G G Y ++++ Sbjct: 1092 SGTGNYIVNLQ 1102
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.8 bits (95), Expect = 2e-05 Identities = 30/194 (15%), Positives = 67/194 (34%), Gaps = 12/194 (6%) Query: 201 QPQIATVKRDATIANAEREKEARIEKARAEKEAKEAEYQRDAQIAEAEKHKELKVQSYKR 260 P + T AE K+ + E++A E Q EA+ + + Q+ + Sbjct: 1026 PPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEV 1085 Query: 261 EQEQARADADLSYELQQAKAQQGVTEEQMRVKIIEREKQIELEEKEIARREKQYDAEVKK 320 Q + E Q + ++ T E+ E + ++E E+ + + + ++ Sbjct: 1086 AQSGSETK-----ETQTTETKETATVEK------EEKAKVETEKTQEVPKVTSQVSPKQE 1134 Query: 321 KADADRYAVEQSAEAEKVKQIKKADADQYKIEAEARARAEEVRVEGLAKAEIEKAQGQAK 380 +++ + E + E + IK+ + A+ A+E Sbjct: 1135 QSETVQPQAEPARENDPTVNIKEPQSQTNT-TADTEQPAKETSSNVEQPVTESTTVNTGN 1193 Query: 381 AEVQKAQGTAEADV 394 + V+ + T A Sbjct: 1194 SVVENPENTTPATT 1207
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.008 Identities = 25/132 (18%), Positives = 51/132 (38%), Gaps = 27/132 (20%) Query: 403 LKIEFMLDRESSLDKLSPPIESNYVVSILGNLITNAFE-AIERNEEHDKKVRMFVTDIGE 461 L+ E ++ + +D PP+ ++ L+ N + I + + K+ + T Sbjct: 240 LQFENQIN-PAIMDVQVPPM-------LVQTLVENGIKHGIAQLPQ-GGKILLKGTKDNG 290 Query: 462 EIVIEVEDSGQGIHDEVITSIFYKGFSTKEGEKRGYGLAKVKELVEDLNG---SIAIEKG 518 + +EVE++G E G GL V+E ++ L G I + + Sbjct: 291 TVTLEVENTGSLALKNT-------------KESTGTGLQNVRERLQMLYGTEAQIKLSEK 337 Query: 519 DLGGALFIIALP 530 G ++ +P Sbjct: 338 Q-GKVNAMVLIP 348
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.7 bits (74), Expect = 0.002 Identities = 13/32 (40%), Positives = 16/32 (50%) Query: 44 VLVGPSGCGKSTLLRMIAGLEEISSGDLIINE 75 VL G G GKSTL+ + GL+ S I Sbjct: 600 VLEGTGGIGKSTLINTLVGLDFFSDTHFDIGT 631
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 40.9 bits (95), Expect = 9e-06 Identities = 72/327 (22%), Positives = 119/327 (36%), Gaps = 43/327 (13%) Query: 131 IKKDKYDTSKLEKAITNYYSVDGKMYSMPFNSSTPVLIYNKDAFAKAGLDPEKAPKTYAE 190 I DK KL + +GK+ + P LIYNKD PKT+ E Sbjct: 105 ITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLP-------NPPKTWEE 157 Query: 191 LQEAAKKLTIKEGGNVKQYGFSMLNYGWFFEELLATQGALYVDNENGRKDAAKKAVFNGK 250 + K+L K G + + + W L+A G ENG+ D V N Sbjct: 158 IPALDKELKAK-GKSALMFNLQEPYFTW---PLIAADGGYAFKYENGKYDIKDVGVDNAG 213 Query: 251 EGQKVFGMLDELNKAGALGKYGASWDDIRAAFQSGQVAMYLDSSAGVRDLIDASKFNVGV 310 + ++D + + AAF G+ AM ++ + ID SK N GV Sbjct: 214 AKAGLTFLVDLIKNKHM--NADTDYSIAEAAFNKGETAMTINGPWAWSN-IDTSKVNYGV 270 Query: 311 SYIPYPEDSKQN---GVVIGGASLWMTNMVSEETQQGAWDFMKYLTKPDVQAKWHTATGY 367 + +P + GV+ G + N K L K ++ T G Sbjct: 271 TVLPTFKGQPSKPFVGVLSAGINAASPN--------------KELAKEFLENYLLTDEGL 316 Query: 368 FSINPD----AYNEPLVKEQYEKYPQLKVTVDQLQATKQSPATQGALISVFPESRDAVVK 423 ++N D A +E+ K P++ T++ Q +G ++ P+ Sbjct: 317 EAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQ--------KGEIMPNIPQMSAFWYA 368 Query: 424 ALEAMYDGENSKEALDEAAKATDRAIS 450 A+ + + ++ +DEA K I+ Sbjct: 369 VRTAVINAASGRQTVDEALKDAQTRIT 395
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 6e-24 Identities = 35/140 (25%), Positives = 67/140 (47%), Gaps = 2/140 (1%) Query: 2 RLLVVEDNASLLESIVQILCDE-FEVDTALNGEDGLFLALQNIYDAILLDVMMPEMDGFE 60 +LV +D+A++ + Q L ++V N D ++ DV+MP+ + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 61 VIQKIRDEKIETPVLFLTARDSLEDRVKGLDFGGDDYIVKPFQAPELKARI-RALLRRSG 119 ++ +I+ + + PVL ++A+++ +K + G DY+ KPF EL I RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 120 SLTTKQTIRYKGIELFGKDK 139 + + G+ L G+ Sbjct: 125 RPSKLEDDSQDGMPLVGRSA 144
>PF06580#Sensor histidine kinase Length = 349 Score = 39.5 bits (92), Expect = 2e-05 Identities = 34/198 (17%), Positives = 70/198 (35%), Gaps = 53/198 (26%) Query: 234 TISKECRRLSKLVANLLL---------LARSDSNQIEMDKKIFELDKLLEEIVEPYKEIA 284 I +L L S++ Q+ + ++ +V+ Y ++A Sbjct: 181 NIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADEL--------TVVDSYLQLA 232 Query: 285 SYQEKEMILKVEYDISFMGDRERIHQMMV------ILLDNAMKY----TNEGGHIQIDCT 334 S Q ++ L+ E I+ I + V L++N +K+ +GG I + T Sbjct: 233 SIQFEDR-LQFENQIN-----PAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGT 286 Query: 335 QTNSSIRIRVKDDGIGVKGEDIPKLFDRFYQGDKARSASEGAGLGLSIANWIVEKHYGK- 393 + N ++ + V++ G ++ E G GL ++ YG Sbjct: 287 KDNGTVTLEVENTG-----------------SLALKNTKESTGTGLQNVRERLQMLYGTE 329 Query: 394 --ISVESQWGEGTCFEVI 409 I + + G+ +I Sbjct: 330 AQIKLSEKQGKVNAMVLI 347
>PF06580#Sensor histidine kinase Length = 349 Score = 37.9 bits (88), Expect = 7e-05 Identities = 20/99 (20%), Positives = 42/99 (42%), Gaps = 19/99 (19%) Query: 434 LIDNALE-AVTNCEKK-RVEVKIQHED-ILTITVQDTGKGIQEKEIEELFTKGYSTKGDN 490 L++N ++ + + ++ +K ++ +T+ V++TG + E + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------S 310 Query: 491 RGYGLYLVKESIQRINGE---IHMHSLVGKGTTITIEIP 526 G GL V+E +Q + G I + GK + IP Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNA-MVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 2e-19 Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 5/129 (3%) Query: 2 IKVLIVEDDPMVAMLNTHYLEQVGGFELVQAVNSIKSAIEVLEESRIDLVLLDIFMPEET 61 +L+ +DD + + L + G V+ ++ + + DLV+ D+ MP+E Sbjct: 4 ATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GFELLMYIRNQEKEIDIMMISAVHDMGSIKKALQYGVVDYLIKPFTFERFKEALTIYREK 121 F+LL I+ ++ ++++SA + + KA + G DYL KPF E + I Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT---ELIGIIGRA 118 Query: 122 LTFMKEQQK 130 L K + Sbjct: 119 LAEPKRRPS 127
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.0 bits (88), Expect = 5e-06 Identities = 20/87 (22%), Positives = 31/87 (35%), Gaps = 4/87 (4%) Query: 59 GAFKDGKLIGVATLETKPYVKQEHKAKIGSVYVSPKARGLGAGKALIKECLELAKSLEVE 118 + + IG + + A I + V+ R G G AL+ + +E AK Sbjct: 69 LYYLENNCIGRIKIRSN----WNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFC 124 Query: 119 QVMLDVVVGNDGAKKLYESLGFKTFGV 145 +ML+ N A Y F V Sbjct: 125 GLMLETQDINISACHFYAKHHFIIGAV 151
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 30.7 bits (69), Expect = 0.013 Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 9/87 (10%) Query: 152 KKSKFITTVSP-IHTTEFQGKLYMLLKTSFLENMLLKLMKQFLIISVLTIILTTISVFIF 210 + + V+P + T G L+ + + F LLK + F+ +II+ T V Sbjct: 312 EIQDKMAAVAPHLDLTVDYGWLWFISQPLF---KLLKWIHSFVGNWGFSIIIITFIV--- 365 Query: 211 SRVITEPL-IKMKRATEKMSKLNKPIQ 236 R I PL + KM L IQ Sbjct: 366 -RGIMYPLTKAQYTSMAKMRMLQPKIQ 391
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.1 bits (234), Expect = 1e-24 Identities = 34/121 (28%), Positives = 64/121 (52%), Gaps = 1/121 (0%) Query: 3 KILLVDDEERMLRLLDLFLSPRGYFCMKATSGLEALKLIEQKDFDIILLDVMMPNMDGWD 62 IL+ DD+ + +L+ LS GY ++ + I D D+++ DV+MP+ + +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 TCYQIRQI-SNVPIIMLTARNQNYDMVKGLTMGADDYITKPFDEHVLVARIEAILRRTKK 121 +I++ ++P+++++A+N +K GA DY+ KPFD L+ I L K+ Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 D 122 Sbjct: 125 R 125
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 42.6 bits (100), Expect = 1e-07 Identities = 29/123 (23%), Positives = 42/123 (34%), Gaps = 7/123 (5%) Query: 23 TKNPEAFSSSYEDVLKHEDPVAAMAKRLSNPDKYTLGVFKDKDLIGIATLETKPFIKQEH 82 T E FS Y K + + K + + + IG + + Sbjct: 36 TYTEERFSKPY---FKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSN----WNG 88 Query: 83 KAKIGSVFVSPKARGLGAGRALIKAIIENADKLHVEQLMLDVVVGNDAAKKLYESLGFQT 142 A I + V+ R G G AL+ IE A + H LML+ N +A Y F Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148 Query: 143 YGV 145 V Sbjct: 149 GAV 151
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 565 bits (1458), Expect = 0.0 Identities = 222/1039 (21%), Positives = 447/1039 (43%), Gaps = 55/1039 (5%) Query: 4 LTKFSLKNRAAVIIMVFLISILGVYSGSKLPMEFLPSIDNPAVTVTTLSPGLDAEAMTKE 63 + F ++ ++ ++ + G + +LP+ P+I PAV+V+ PG DA+ + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 64 VTDPLEKQFRNLEHIDNITS-STHEGLSRIDIAYTSKANMKDATREVEKAINTIK--LPK 120 VT +E+ ++++ ++S S G I + + S + A +V+ + LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 DATKPIVSQLNTTMIPLAQIAIQKQNGFSKADE--KQIEKEIVPQLESIDGVANVMFFGK 178 + + +S ++ L N + D+ + + L ++GV +V FG Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 179 STSELSIILDPNQLKDKNVTTEQILKVLQGKETSTPAG------AVTVNKEEYNLRVIGD 232 + + I LD + L +T ++ L+ + AG A+ + ++ Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 233 IKNVDDIKNITVAP-----HVKLQDVAQIEL-KQHYDTISHINGEEGTGLIIMKEPSKNA 286 KN ++ +T+ V+L+DVA++EL ++Y+ I+ ING+ GL I NA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 287 VAIGKEIDKKIKDISKQYKDQFSIKLLASTHEQVENAVTSMGKEVILGAIAATLIILIFL 346 + K I K+ ++ + + T V+ ++ + K + + L++ +FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 347 RNFRTTLIAVVSIPLSILLTLFLLHQSNITLNTLTLGGLAVAVGRLVDDSIVVIENIFRR 406 +N R TLI +++P+ +L T +L ++NTLT+ G+ +A+G LVDD+IVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 407 LQKEYFS-KDIILDATKEVAVAITSSTLTTVAVFLPIGLVSGVIGKLMLPMVLAVVYSIL 465 + ++ K+ + ++ A+ + AVF+P+ G G + + +V ++ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 466 SSLIVALTVVPLMAFLLLKKIK---HKKPS------------SSPRYVATLKWALSHKFI 510 S++VAL + P + LLK + H+ S Y ++ L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 511 ILLTSFLLFAGSIAAYVLLPKANIKSEDDTMLSINMTFPADYALETQKQKAFDFEKKLLS 570 LL L+ AG + ++ LP + + ED + + PA E ++ L Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 571 NSDVTD-VILRMGSSAEDAQWGQTTKNNLASIFVVFK-----------KGSDIDQYIKEL 618 N + + + GQ N FV K + I + EL Sbjct: 600 NEKANVESVFTVNGFSFS---GQA--QNAGMAFVSLKPWEERNGDENSAEAVIHRAKMEL 654 Query: 619 KKEHNAF-EPAELDYIKTSYSSSGGGNNLQFNVTATNETNLKKAATIVETKLKNMDDLSK 677 K + F P + I +++G L ++ + ++ ++ L Sbjct: 655 GKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVS 714 Query: 678 VKTNLEDSKKEWQIHVDQTKAEQLGLTPELAAQQVAFLMKKSPIGEVSINNEKTTIMIEH 737 V+ N + ++++ VDQ KA+ LG++ Q ++ + + + + + ++ Sbjct: 715 VRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQA 774 Query: 738 KKESITKQEDILNTNILSPINGPIPLKDIATISEKQLQTEVFHKDGKETIQITAEASNED 797 + ED+ + S +P T + +G +++I EA+ Sbjct: 775 DAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGT 834 Query: 798 LSKVSAEVNKAITDLDLPSGAKVNIAGATESMQENFTDLFKIMGIAIGIVYLIMVITFGQ 857 S + + + + LP+G + G + + + ++ I+ +V+L + + Sbjct: 835 SSGDAMALMENLAS-KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYES 893 Query: 858 ARAPFAILFSLPLAAVGGILGLIISGTPVDVNSLIGALMLIGIVVTNAIVLIERVQQNRE 917 P +++ +PL VG +L + DV ++G L IG+ NAI+++E + E Sbjct: 894 WSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLME 953 Query: 918 H-GMETREALLEAGSTRLRPIIMTAITTIVAMLPLLFGQSQAGSMVSKSLAVVVIGGLAV 976 G EA L A RLRPI+MT++ I+ +LPL + AGS ++ + V+GG+ Sbjct: 954 KEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAIS-NGAGSGAQNAVGIGVMGGMVS 1012 Query: 977 STVLTLVVVPVMYELLDKI 995 +T+L + VPV + ++ + Sbjct: 1013 ATLLAIFFVPVFFVVIRRC 1031 Score = 127 bits (321), Expect = 5e-32 Identities = 96/518 (18%), Positives = 198/518 (38%), Gaps = 42/518 (8%) Query: 509 FIILLTSFLLFAGSIAAYVLLPKANIKSEDDTMLSINMTFPADYALETQKQKAFDFEKKL 568 F +L L+ AG++A + LP A + +S++ +P A Q Sbjct: 11 FAWVLAIILMMAGALA-ILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT--------- 60 Query: 569 LSNSDVTDVILR--MGSSAEDAQWGQTTKNNLASIFVVFKKGSDIDQYIKELKKEHNAFE 626 VT VI + G + +I + F+ G+D D +++ + Sbjct: 61 -----VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLAT 115 Query: 627 P-----AELDYIKTSYSSSGGGNNLQFNVTATNETNLKK---AATIVETKLKNMDDLSKV 678 P + I SSS F T A+ V+ L ++ + V Sbjct: 116 PLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDV 175 Query: 679 KTNLEDSKKEWQIHVDQTKAEQLGLTPE-----LAAQQVAFLMKKSPIGEVSINNEKTTI 733 L ++ +I +D + LTP L Q + G ++ ++ Sbjct: 176 --QLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQ-IAAGQLGGTPALPGQQLNA 232 Query: 734 MIEHKKESITKQEDILNTNILSPING-PIPLKDIATISE-KQLQTEVFHKDGKETIQIT- 790 I + E+ + +G + LKD+A + + + +GK + Sbjct: 233 SIIAQTRFKNP-EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGI 291 Query: 791 AEASNEDLSKVSAEVNKAITDL--DLPSGAKVNIA-GATESMQENFTDLFKIMGIAIGIV 847 A+ + + + + +L P G KV T +Q + ++ K + AI +V Sbjct: 292 KLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLV 351 Query: 848 YLIMVITFGQARAPFAILFSLPLAAVGGILGLIISGTPVDVNSLIGALMLIGIVVTNAIV 907 +L+M + RA ++P+ +G L G ++ ++ G ++ IG++V +AIV Sbjct: 352 FLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIV 411 Query: 908 LIERVQQ-NREHGMETREALLEAGSTRLRPIIMTAITTIVAMLPLLFGQSQAGSMVSKSL 966 ++E V++ E + +EA ++ S ++ A+ +P+ F G++ + Sbjct: 412 VVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIY-RQF 470 Query: 967 AVVVIGGLAVSTVLTLVVVPVMYELLDKIGRKRRSRRK 1004 ++ ++ +A+S ++ L++ P + L K K Sbjct: 471 SITIVSAMALSVLVALILTPALCATLLKPVSAEHHENK 508 Score = 94.1 bits (234), Expect = 1e-21 Identities = 74/516 (14%), Positives = 174/516 (33%), Gaps = 41/516 (7%) Query: 3 RLTKFSLKNRAAVIIMVFLISILGVYSGSKLPMEFLPSIDNPAVTVT-TLSPGLDAE--- 58 L + +++ LI V +LP FLP D L G E Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 59 -AMTKEVTDPLEKQFRNLEHIDNITSSTHEGLSRID-IAYTSKANMKDATR---EVEKAI 113 + + L+ + N+E + + + G ++ +A+ S ++ E I Sbjct: 588 KVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVI 647 Query: 114 NTIKLPKDATK---------PIVSQLNTTMIPLAQIAIQKQNGFSKADEKQIEKEIVPQL 164 + K+ + P + +L T + Q G Q +++ Sbjct: 648 HRAKMELGKIRDGFVIPFNMPAIVELGTATG--FDFELIDQAGLGHDALTQARNQLLGMA 705 Query: 165 -ESIDGVANVMFFGKS-TSELSIILDPNQLKDKNVTTEQILKVLQGKETSTPAGAVTVNK 222 + + +V G T++ + +D + + V+ I + + T Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 223 EEYNLRVIGD---IKNVDDIKNITVAPH----VKLQDVAQIELKQHYDTISHINGEEGTG 275 L V D +D+ + V V + NG Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSME 825 Query: 276 LIIMKEPSKNAVAIGKEIDKKIKDISKQYKDQFSIKLLASTHEQVENAVTSMGKEVILGA 335 + P ++ + +++++ + ++++ S + L A Sbjct: 826 IQGEAAPGTSS----GDAMALMENLASKLPAGIGYDWTGMSYQERL----SGNQAPALVA 877 Query: 336 IAATLIILIF---LRNFRTTLIAVVSIPLSILLTLFLLHQSNITLNTLTLGGLAVAVGRL 392 I+ ++ L ++ + ++ +PL I+ L N + + GL +G Sbjct: 878 ISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLS 937 Query: 393 VDDSIVVIENIFRRLQKEYFS-KDIILDATKEVAVAITSSTLTTVAVFLPIGLVSGVIGK 451 ++I+++E ++KE + L A + I ++L + LP+ + +G Sbjct: 938 AKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSG 997 Query: 452 LMLPMVLAVVYSILSSLIVALTVVPLMAFLLLKKIK 487 + + V+ ++S+ ++A+ VP+ ++ + K Sbjct: 998 AQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCFK 1033
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 32.0 bits (72), Expect = 0.004 Identities = 14/68 (20%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 50 KEFYKEENLAAFIVYGM-NKAKNLPQFHKDEIPTLVRILRLCQEIGWYEEANTFMVNQGL 108 F+ + I+YG+ + + IPTLV LR +G+Y + +++ L Sbjct: 129 YTFFSNRDRVQAIIYGLEDSGRTYTADDDKGIPTLVEFLRAGYYLGFYNKQLSYLNTPQL 188 Query: 109 AEFVHTSL 116 ++ Sbjct: 189 KNECLPAM 196
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.004 Identities = 17/71 (23%), Positives = 27/71 (38%), Gaps = 14/71 (19%) Query: 284 AAQGNVSIQAAAAGKVVKSYYSASYGNVVFIAHQINGKLYTTVYAHMKDRTVQAGDQVQA 343 + G V I A A GK+ S G I N + K+ V+ G+ V+ Sbjct: 75 SVLGQVEIVATANGKLTHS------GRSKEIKPIENSIV--------KEIIVKEGESVRK 120 Query: 344 GQLVGHMGNTG 354 G ++ + G Sbjct: 121 GDVLLKLTALG 131
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.014 Identities = 11/32 (34%), Positives = 15/32 (46%) Query: 39 GPSGCGKSTLFRLITGLEEASTGQIELTETKS 70 G G GKSTL + GL+ S ++ K Sbjct: 603 GTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 112 bits (281), Expect = 6e-31 Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 1/130 (0%) Query: 1 MSKYRVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETDHYDFVVLDIMMPEM 60 M+ +LV DD++ +R ++ L GY+ N + + D VV D++MP+ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLSVCKEIRKT-SDVPIIFLTAKGEEWNRVNGLRMGADDYIVKPFSPGELIARMEAVLR 119 + + I+K D+P++ ++A+ + GA DY+ KPF ELI + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RYTKQEQQEE 129 ++ + E Sbjct: 121 EPKRRPSKLE 130
>PF06580#Sensor histidine kinase Length = 349 Score = 39.1 bits (91), Expect = 2e-05 Identities = 30/188 (15%), Positives = 73/188 (38%), Gaps = 32/188 (17%) Query: 275 EKVTQLIHKEADRMQRLVHDLLDL--AQLEGEHFPLQKQPIVFSQ---LIEDVLDTYEIK 329 + LI ++ + + ++ L +L L + + + +++ L I+ Sbjct: 180 NNIRALILEDPTKAREMLTSLSELMRYSLRYS----NARQVSLADELTVVDSYLQLASIQ 235 Query: 330 FIEKKIRISTNLNPEII-VMIDEDRMQQVLHNVLDNAIRYTNQNGDIMITLRQIDDYCEL 388 F E +++ +NP I+ V + +Q ++ N + + I Q G I++ + + L Sbjct: 236 F-EDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTL 294 Query: 389 SIKDTGIGIDTEHLENLGERFYRVDKARSRQHGGTGLGLAIVRQ-IVHIHDGQW--QIES 445 +++TG A TG GL VR+ + ++ + ++ Sbjct: 295 EVENTG------------------SLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSE 336 Query: 446 EKGNGTTV 453 ++G + Sbjct: 337 KQGKVNAM 344
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 31.6 bits (71), Expect = 0.007 Identities = 22/87 (25%), Positives = 35/87 (40%), Gaps = 7/87 (8%) Query: 88 KTKEEAAKYIQDVAKKKQAKKVVKSKSMVTEEISMNHALEEIGCEVLE--SDLGEYILQV 145 KT++E K + K + K T+++ L++I +VLE S+LG I Sbjct: 53 KTEKEKFKDSINNLVKTEFTNETLDKIQQTQDL-----LKKIPKDVLEIYSELGGEIYFT 107 Query: 146 DNDPPSHIIAPALHKNRTQIRDVFKEK 172 D D H L + + EK Sbjct: 108 DIDLVEHKELQDLSEEEKNSMNSRGEK 134
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 133 bits (335), Expect = 7e-40 Identities = 64/264 (24%), Positives = 122/264 (46%), Gaps = 35/264 (13%) Query: 4 YVYALLVGMVFGSFFMLIAMRIPL------------------------GESIIIPRSHCH 39 + L ++ GSF ++ R+P+ ++++PRS C Sbjct: 16 FSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEPPYNLMVPRSCCP 75 Query: 40 YCKYVLKPKELIPIISFCIQRGRCTNCKRKISILYVIFELVTGIICLLTVYMIGVERELI 99 +C + + E IP++S+ RGRC C+ IS Y + EL+T ++ + + + Sbjct: 76 HCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAVAMTLAPGWGTL 135 Query: 100 IILSLFSLLLIISVTDYIYMLIPNRI---LAWFSCLLILECVFVPLVTWTESIVGSGVIF 156 L L +L+ ++ D ML+P+++ L W L L FV L ++++G+ + Sbjct: 136 AALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLG---DAVIGAMAGY 192 Query: 157 ILLYCMQKIY-----PEGLGGGDIKLLSLLGFIAGLKGVFMILFLSSFFSLCFFGAGLVL 211 ++L+ + + EG+G GD KLL+ LG G + + ++L LSS ++L Sbjct: 193 LVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLILL 252 Query: 212 KRMKMRTQIPFGPFISLGAICYML 235 + IPFGP++++ +L Sbjct: 253 RNHHQSKPIPFGPYLAIAGWIALL 276
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 31.1 bits (70), Expect = 0.001 Identities = 10/28 (35%), Positives = 15/28 (53%) Query: 20 NTVSSNIANANTPGYKAQDVTFAEQMNK 47 NT S+NI++ N GY Q A+ + Sbjct: 19 NTASNNISSYNVAGYTRQTTIMAQANST 46
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 33.0 bits (75), Expect = 3e-04 Identities = 19/75 (25%), Positives = 32/75 (42%), Gaps = 7/75 (9%) Query: 5 INASGSGLTTARKWMEVTSNNIVNANTTAAPGADLYERRSVVLESNNSFANMLDGSPTNG 64 IN + SGL A+ + SNNI + N Y R++ ++ NS G NG Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAG------YTRQTTIMAQANSTLGA-GGWVGNG 56 Query: 65 VKIKSIEADKTENLV 79 V + ++ + + Sbjct: 57 VYVSGVQREYDAFIT 71 Score = 28.0 bits (62), Expect = 0.013 Identities = 10/38 (26%), Positives = 17/38 (44%) Query: 97 NIDVTAEMTNVMVAQKMYEANTSVLNANKKMLDKDLEI 134 +++ E N+ Q+ Y AN VL + D + I Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 35.4 bits (81), Expect = 5e-06 Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 1/77 (1%) Query: 24 SQTSVVEGKKFIDLLEDMNQTQNNAQTAVYDLLTKGVG-ETHDVLIQQKKAESQMKTAAL 82 Q ++ + L+ ++ TQ A+T G +DV+ +KA M+ Sbjct: 27 PQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQ 86 Query: 83 VRDNLIENYKSLINMQI 99 VR+ L+ Y+ +++MQ+ Sbjct: 87 VRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 162 bits (411), Expect = 3e-46 Identities = 87/459 (18%), Positives = 185/459 (40%), Gaps = 42/459 (9%) Query: 17 LVIGAALLAIVTGALLYFTLPDKYVVVYQNLNDADKQEITAELSKLGVDYQLAADG-SIR 75 +V G+A +AIV +L+ PD Y ++ NL+D D I A+L+++ + Y+ A +I Sbjct: 28 IVAGSAAVAIVVAMVLWAKTPD-YRTLFSNLSDQDGGAIVAQLTQMNIPYRFANGSGAIE 86 Query: 76 VQKNDAPWVRKEMNGMGLPFNSKSGEEILLESSLGSSEQDKKMKQIVGTKKQLEQDIVRN 135 V + +R + GLP G E+L + G S+ +++ + +L + I Sbjct: 87 VPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELARTI-ET 145 Query: 136 FATVETANVQITLPEKETIFDEEKAKGTAAITVGVKRGQLLTADQVAGIQQMISAAVPGV 195 V++A V + +P+ ++F E+ +A++TV ++ G+ L Q++ + ++S+AV G+ Sbjct: 146 LGPVKSARVHLAMPKP-SLFVREQKSPSASVTVTLEPGRALDEGQISAVVHLVSSAVAGL 204 Query: 196 KAEEVSVIDSKKGVISKGADEAHSTSSSSYEKEVEMQHQIEGKLKQDIDATLMTMFKPNE 255 V+++D ++++ + + ++ + +E ++++ I+A L + Sbjct: 205 PPGNVTLVDQSGHLLTQSNTSGRDLNDAQ----LKFANDVESRIQRRIEAILSPIVGNGN 260 Query: 256 YKVNTKVSVNYDEVTRQSEKYG-DKGVLRSKQEQEESSTAQEGAETKQGA--GITANG-- 310 +++ + E Y + ++ + + +++ G G +N Sbjct: 261 VHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPGALSNQPA 320 Query: 311 -------EVPNYGTNNNQNGKIVYDNKNGNKI----------ENYEIDKTVETIKKHP-E 352 P N QN + N N NYE+D+T+ K + + Sbjct: 321 PPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDRTIRHTKMNVGD 380 Query: 353 LTKTNVVVWVDNDTLVKRKI------DMTTFKEAIGTAAGLQADPNGNFTNGQVNVVTVQ 406 + + +V V V+ TL K M ++ A G +NVV Sbjct: 381 IERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMGFSDK-----RGDTLNVVNSP 435 Query: 407 FDQPKEEKKKEPEESGINWWLFGGIPAGLLAIGGLVWFF 445 F + P ++ L + + W Sbjct: 436 FSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWIL 474
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 200 bits (511), Expect = 4e-64 Identities = 116/336 (34%), Positives = 197/336 (58%), Gaps = 6/336 (1%) Query: 2 LDEISSKEKAAILIRTLEEGVAAKVIEYMTAKEKEVLLREIAKFRVYKSETLENVLGEFL 61 + ++ K+KAAIL+ ++ +++KV +Y++ +E E L EIAK SE +NVL EF Sbjct: 12 VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFK 71 Query: 62 YELNVKELNLVTPDKEYIRRIF-KNMPEDELEKLLEDLWYN-KDNPFEFLNSLTDLEPLL 119 EL + + + +Y R + K++ + ++ +L + PFEF+ D +L Sbjct: 72 -ELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRA-DPANIL 129 Query: 120 TVLNDESPQTIAIIASYIKPQLASQLIERLPDHKRVETVMGIAKLEQVDGELINQIGDLL 179 + E PQTIA+I SY+ PQ AS ++ LP + IA +++ E++ ++ +L Sbjct: 130 NFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVL 189 Query: 180 KSKLNNMAFNAINKTDGLKTIVNILNNVSRGVEKTVFQKLDEMDYELSEKIKENMFVFED 239 + KL +++ G+ +V I+N R EK + + L+E D EL+E+IK+ MFVFED Sbjct: 190 EKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFED 249 Query: 240 LLGLEDLALRRVLEEITDNGVIAKALKIAKEEIKEKLFTCMSSNRKEMILEELDGLGPLK 299 ++ L+D +++RVL EI D +AKALK ++EK+F MS M+ E+++ LGP + Sbjct: 250 IVLLDDRSIQRVLREI-DGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTR 308 Query: 300 MTDAEKAQQTITDTVKKLEKEGRIIVQRG-EDDVLI 334 D E++QQ I ++KLE++G I++ RG E+DVL+ Sbjct: 309 RKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVLV 344
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.7 bits (178), Expect = 4e-18 Identities = 35/191 (18%), Positives = 70/191 (36%), Gaps = 33/191 (17%) Query: 1 MAKPN----VVNKEKLLQAAKEIIAEHGMEKLTLKAVAESAQVTQGTVYYHFKTKDQLLL 56 MA+ ++ +L A + ++ G+ +L +A++A VT+G +Y+HFK K L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 57 EVTEAFCKASWEQIGKDVQLEKALQSAESRCVKDSMYHHLFFQLVASGLQNDAMKDKIGG 116 E+ + S IG+ +A + V + H+ S + + + + Sbjct: 61 EI----WELSESNIGELELEYQAKFPGDPLSVLREILIHVL----ESTVTEERRRLLMEI 112 Query: 117 LLHYENQQ--------------------LTRVLNKNI-GGTMTSQISTETWSVLCNALID 155 + H + + L I + + + T +++ I Sbjct: 113 IFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYIS 172 Query: 156 GLELQALFNPS 166 GL LF P Sbjct: 173 GLMENWLFAPQ 183
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.0 bits (96), Expect = 6e-06 Identities = 40/229 (17%), Positives = 86/229 (37%), Gaps = 11/229 (4%) Query: 55 FATTLVCGSLPRMICGPIAGAVADRVSRRWLVIGTDLLSSLTMLIMFILATIFGPSLPFI 114 + L +L + C P+ GA++DR RR +++ + +++ IM P L + Sbjct: 45 YGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIM-----ATAPFLWVL 99 Query: 115 YISAALLSICASFYSVALTSSIPNLVDEGRIQKASALNQTAASLSNILGPIIGGVVFGFL 174 YI + I + +VA + I ++ D + + GP++GG++ G Sbjct: 100 YIGRIVAGITGATGAVA-GAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLM-GGF 157 Query: 175 SIQSFFLLNSITFFLAVILQLFIVFDLYKKEVAESKEHFLTSIKEGFSYVKRQHEIYGLM 234 S + F + L + F++ + +K E + L + F + + + LM Sbjct: 158 SPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREAL-NPLASFRWARGMTVVAALM 216 Query: 235 KIALWVNFFACGLTVALPYIIVHTLHLSSKQLGTVEGMLAVGMLMGAIT 283 + + H + +G LA ++ ++ Sbjct: 217 AVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGI---SLAAFGILHSLA 262 Score = 33.6 bits (77), Expect = 0.001 Identities = 17/97 (17%), Positives = 35/97 (36%), Gaps = 2/97 (2%) Query: 76 VADRVSRRWLVIGTDLLSSLTMLIMFILATIFGPSLPFIYISAALLSICASFYSVALTSS 135 + V+ R +L + +IL ++ +L AL + Sbjct: 266 ITGPVAARLGERRALMLGMIADGTGYILLAFATRG--WMAFPIMVLLASGGIGMPALQAM 323 Query: 136 IPNLVDEGRIQKASALNQTAASLSNILGPIIGGVVFG 172 + VDE R + SL++I+GP++ ++ Sbjct: 324 LSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA 360
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 27.0 bits (59), Expect = 0.047 Identities = 33/151 (21%), Positives = 60/151 (39%), Gaps = 16/151 (10%) Query: 40 ATMWFEKAEKEKSGNEAKSYKEMAEKMDHGATALKDGKYLEAKDIANEVLQMKKDDALET 99 AT + A+ +K+ E + + A + A A +D KDI NE L+ Sbjct: 53 ATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRHNASRTPSA 112 Query: 100 AVTSNAENM----------LQKAKDVEKKVNERVAK------RRKVEEEEGIDKLIKAVD 143 ++A N L KA++ +K E K +R+ E E + + + Sbjct: 113 TELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLK 172 Query: 144 SIDDVKEKEKKVSEALDKAEEAQAKIEAKKN 174 + +++ +SE E AQ K+ A ++ Sbjct: 173 LAEAEEKRLAALSEEAKAVEIAQKKLSAAQS 203
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 29.6 bits (66), Expect = 0.016 Identities = 18/64 (28%), Positives = 25/64 (39%), Gaps = 13/64 (20%) Query: 123 TLMVKT--APEIRTMLQNHEINLGVISAAPFDESLLKQTNVMPDTLVLAFSKEHHFSKKE 180 TL++ + A RTM+ N + KQ N TL S EH S + Sbjct: 914 TLLIDSHDAGYARTMIDATSAN-----------EITKQLNTATTTLNNIASLEHKTSGLQ 962 Query: 181 NVSL 184 +SL Sbjct: 963 TLSL 966
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.007 Identities = 14/41 (34%), Positives = 19/41 (46%), Gaps = 7/41 (17%) Query: 32 TLLGPSGCGKTTLLRMIAGLEEPDKGEIYFGDTCMYSSTKK 72 L G G GK+TL+ + GL+ +F DT T K Sbjct: 600 VLEGTGGIGKSTLINTLVGLD-------FFSDTHFDIGTGK 633
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 28.5 bits (63), Expect = 0.045 Identities = 78/308 (25%), Positives = 116/308 (37%), Gaps = 69/308 (22%) Query: 40 EKKIVVYSAGPKG---LAEKIQKDFEKKTGIKVEMFQGTTGKILARMEAEKKKPVVDV-- 94 E K+V++ G KG LAE + K FEK TGIKV + + E+K P V Sbjct: 30 EGKLVIWINGDKGYNGLAE-VGKKFEKDTGIKVTVEHPD--------KLEEKFPQVAATG 80 Query: 95 ----VVLASLPAMEGLKKDGQTLAYKEAKQADKLRSEWSDDKGHYFG------YSASALG 144 ++ + G + G K ++ D Y G + AL Sbjct: 81 DGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALS 140 Query: 145 IVYNTKNVKTAPEDWSDI--------TKGEWKGKVNLPDP--------ALSGSALDFVTG 188 ++YN + P+ W +I KG+ NL +P A G A + G Sbjct: 141 LIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENG 200 Query: 189 -YVKKN-------GKDGWDLFEQLKKNEVTVAGANQEALDPVVT-GAKDMVIAG------ 233 Y K+ K G L KN+ A + + G M I G Sbjct: 201 KYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSN 260 Query: 234 -----VDY-MTYSAKAKGEPVDIVYPKSGTVISPRAAGIMKDSKNVEGAKEFID-YLLSD 286 V+Y +T KG+P S + +AGI S N E AKEF++ YLL+D Sbjct: 261 IDTSKVNYGVTVLPTFKGQP-------SKPFVGVLSAGINAASPNKELAKEFLENYLLTD 313 Query: 287 DVQKQISK 294 + + ++K Sbjct: 314 EGLEAVNK 321
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 45.3 bits (107), Expect = 1e-07 Identities = 28/106 (26%), Positives = 47/106 (44%) Query: 262 IVMIGVLMLFALIAIGISLVLVAFSKNSASANTMQNLVIVPTCLLAGCYFPYDIMPKAVQ 321 + + V+ L L + +V+ A + + Q LVI P L+G FP D +P Q Sbjct: 148 LYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQ 207 Query: 322 KVADFLPQRWLLDTIAKLQQGIPFSELYVNILILFAFAVAFFLIAI 367 A FLP +D I + G P ++ ++ L + V F ++ Sbjct: 208 TAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLST 253
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 28.6 bits (64), Expect = 0.024 Identities = 15/60 (25%), Positives = 24/60 (40%), Gaps = 14/60 (23%) Query: 122 LDNGYIVIFGGGNGQPFVTT-------------DYPSVQRAIEMNSDAILVAKQGVDGVF 168 ++ G IVI GG G P + D + A E+N+D ++ V+G Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILT-DVNGAA 241
>PF06580#Sensor histidine kinase Length = 349 Score = 37.5 bits (87), Expect = 8e-05 Identities = 26/130 (20%), Positives = 46/130 (35%), Gaps = 20/130 (15%) Query: 297 LGKDIRFSKHIEGEHAAYHV--YTVLSIFNNLVANAVEAIEDRGLIHIKLYKREQHVIFE 354 ++F I V V ++ N + + + + G I +K K V E Sbjct: 236 FEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLE 295 Query: 355 VIDDGPGIAQKYKKLVFKPGFTSKYDQTGTPSTGIGLSYIDEMVTEL-GGEVRLEDNENG 413 V + G + K+ STG GL + E + L G E +++ +E Sbjct: 296 VENTGSLALKNTKE-----------------STGTGLQNVRERLQMLYGTEAQIKLSEKQ 338 Query: 414 NGCKFIVCLP 423 +V +P Sbjct: 339 GKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 54.1 bits (130), Expect = 3e-10 Identities = 29/177 (16%), Positives = 71/177 (40%), Gaps = 10/177 (5%) Query: 5 IVDDDEVFRSMLSQIIEDGDLGEVIGESEDGAFIEAEQLNYKKVDILFIDLLMPMRDGIE 64 + DDD R++L+Q + I + + + D++ D++MP + + Sbjct: 8 VADDDAAIRTVLNQALSRAGYDVRITSNAATLW---RWIAAGDGDLVVTDVVMPDENAFD 64 Query: 65 TVRHIASSFTG-KIIMISQVESKQLIGEAYTLGVEYYITKPLNKIEVVSVVRKVIERIRL 123 + I + ++++S + +A G Y+ KP + E++ ++ + + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 124 ERSIYDIQKSLNNVFQWEKPQMRNETVQEGKKISDSGRFLLSELGIAGENGS-KDLL 179 S + M+ E + ++ + L+ I GE+G+ K+L+ Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQ-EIYRVLARLMQTDLTLM----ITGESGTGKELV 176
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.4 bits (232), Expect = 3e-24 Identities = 29/123 (23%), Positives = 58/123 (47%), Gaps = 3/123 (2%) Query: 2 PTILVLEDEMPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDGF 61 TILV +D+ IR+ + L RAG+ V S + + D+ + DV++P + F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QVCKAIREENKKIGIIMLTARVQNEDKVQGLGIGADDYIAKPFSP---VELTARIQSLLR 118 + I++ + +++++A+ ++ GA DY+ KPF + + R + + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 119 RIE 121 R Sbjct: 124 RRP 126
>PF06580#Sensor histidine kinase Length = 349 Score = 39.8 bits (93), Expect = 1e-05 Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 22/101 (21%) Query: 359 IVQNAIKY----SHENGKVYIEATKNEGQAVIKVKDDGIGIAKEHLPYIEQSFYQINNHA 414 +V+N IK+ + GK+ ++ TK+ G ++V++ G K N Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK--------------NTK 308 Query: 415 TGAGLGLAIVKKMVELHGG---TINIISKEGIGTTILIKLP 452 G GL V++ +++ G I + K+G ++ +P Sbjct: 309 ESTGTGLQNVRERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 27.0 bits (59), Expect = 0.050 Identities = 18/85 (21%), Positives = 35/85 (41%), Gaps = 11/85 (12%) Query: 80 GVERTGTYNCEGELYAIYLLQEYQGMKIG-------QKLFQAFLSDCKNNDMQSLLVWVV 132 G +RTG + E + I + Q ++ ++LF L + N ++Q + Sbjct: 442 GKDRTGMQDAEIKREIIRKHETGQFSQLNSKLSSEEKRLFSTILMNSGNMEIQEM----N 497 Query: 133 TNNPSKKFYEKFNPEKMDTKFLERV 157 T P K +K ++ + ER+ Sbjct: 498 TGVPGNKVMKKLPLSSLELSYSERI 522
>PF04183#IucA / IucC family Length = 580 Score = 287 bits (736), Expect = 2e-91 Identities = 101/543 (18%), Positives = 192/543 (35%), Gaps = 55/543 (10%) Query: 82 QFYYQMGDSNSVMKADYVTVITFLIKEMSINYG-EGTNPAELMLRVIRSCQNIEEFTKER 140 + + D+ ++ AD + L+ ++ AE M + + + K R Sbjct: 54 IWGWLWIDAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKAR 113 Query: 141 KEDTSALYGFHTSFIEAEQSLLFGHLTHPTPKSRQGILEWKSAMYSPELKGECQLHYFRA 200 + +++ + Q LL GH K R+G + Y+PE +LH+ Sbjct: 114 RGLSASDL--INLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAV 171 Query: 201 HKSIVNEKSLLLDSTTVILKEELRNDEM-VSKEFISKYCNEDEYSLLPIHPLQAEWLLHQ 259 + + + +L + E + + + + LP+HP Q + + Sbjct: 172 KREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIAT 231 Query: 260 PYVQDWIEQGVLEYIGPTGKCYMATSSLRTLYHPDAKYMLKFSFPVKV--TNSMRINKLK 317 ++ D +G + +G G ++A SLRTL + + L P+ + T+ R + Sbjct: 232 DFIAD-FAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGR 290 Query: 318 ELESGLEGKAMLNTAI-GEVLEKFPGFDFICDPAFITL-----------NYGTQESGFEV 365 + +G L + G + +PA + Y QE V Sbjct: 291 YIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEM-LGV 349 Query: 366 IIRENPFYSEHADDATLIAGLVQDAIPGERTRLSNIIHRLADLESRSCEEVSLEWFRRYM 425 I RENP D++ ++ + + + I R E W + Sbjct: 350 IWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRS----GLDAET----WLTQLF 401 Query: 426 NISLKPMVWMYLQYGVALEAHQQNSVVQLKDGYPVKYYFRDNQG-FYFCNSMKEMLNNEL 484 + + P+ + +YGVAL AH QN + +K+G P + +D QG +++ Sbjct: 402 RVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLP 461 Query: 485 AGIGERTGNLYDDYIVDERFRYYL--IFNHMFGLINGFGTAGLIREEILLTELRTVLES- 541 + + T L DY++ + + + + L+ G + E L VL Sbjct: 462 QEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLG----VPERRFYQLLAAVLSDY 517 Query: 542 ----------FLPYNREPSTFLRELLEEDKLACKANLLTRFFDVDELSNPLEQAIYVQVQ 591 F ++ +R +L KL + D+D S L +Q Sbjct: 518 MKKHPQMSERFALFSLFRPQIIRVVLNPVKLT--------WPDLDGGSRMLPN-YLEDLQ 568 Query: 592 NPL 594 NPL Sbjct: 569 NPL 571
>PF04183#IucA / IucC family Length = 580 Score = 584 bits (1507), Expect = 0.0 Identities = 146/602 (24%), Positives = 267/602 (44%), Gaps = 45/602 (7%) Query: 12 IESEDYISVRRRVLRQLVESLIYEGIITPARIEKEEQILFLIQGLDEDNKSVTYECYGRE 71 + +D+ V RR++ +++ L YE + + +++ + G + + E Sbjct: 1 MNHKDWDLVNRRLVAKMLSELEYEQVFHA-ESQGDDRYCINLPG-------AQWR-FIAE 51 Query: 72 RITFGRISIDSLIVRVQDGKQEIQSVAQFLEEVFRVVNVEQTKLDSFIHELEQTIFKDTI 131 R +G + ID+ +R D Q L ++ +V+++ + + +L T+ D Sbjct: 52 RGIWGWLWIDAQTLRCADEPVLAQ---TLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQ 108 Query: 132 AQYER--CNKLKYTQKSYDELENHLIDGHPYHPSYKARIGFQYRDNFRYGYEFMRPIKLI 189 R + + D L+ L+ GHP K R G+ RY E+ +L Sbjct: 109 LLKARRGLSASDLINLNADRLQ-CLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLH 167 Query: 190 WIAAHKKNATVGYENEVIYDKILKSEVGERKLEAYKERIHSMGCDPKQYLFIPVHPWQWE 249 W+A +++ +NE+ ++L + + ++ + + G D +L +PVHPWQW+ Sbjct: 168 WLAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLD-HNWLPLPVHPWQWQ 226 Query: 250 NFIISNYAEDIQDKGIIYLGESADDYCAQQSMRTLRNVTNPKRPYVKVSLNILNTSTLRT 309 I +++ D + ++ LGE D + AQQS+RTL N + +K+ L I NTS R Sbjct: 227 QKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRG 286 Query: 310 LKPYSVASAPAISNWLSNVVSQDSYLRDESRVILLKEFSSVM----YDTNKKATYG---S 362 + +A+ P S WL V + D+ L VIL + + + Y +A Y Sbjct: 287 IPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEM 346 Query: 363 LGCIWRESVHHYLGEQEDAVPFNGLYAKEKDGTPIIDAWLNKYGI--ENWLRLLIQKAII 420 LG IWRE+ +L E V L +++ P+ A++++ G+ E WL L + ++ Sbjct: 347 LGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVV 406 Query: 421 PVIHLVVEHGIALESHGQNMILVHKEGLPVRIALKDFHEGLEFYRPFLKEMNKCPDFTKM 480 P+ HL+ +G+AL +HGQN+ L KEG+P R+ LKDF + + EM+ P + Sbjct: 407 PLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRD 466 Query: 481 HKTYANGKMNDFFEMDRIECLQEMVLDALFLFNVGELAFVLADKYEWKEESFWMIVVEEI 540 + + D+ D L V L + E F+ ++ + Sbjct: 467 VTSRLS---ADYLIHD---------LQTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVL 514 Query: 541 ENHFRKYPHLKDRFESIQLYTPTFYAEQLTKRRL-YIDVESLVHEVP-------NPLYRA 592 ++ +K+P + +RF L+ P L +L + D++ +P NPL+ Sbjct: 515 SDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLWLV 574 Query: 593 RQ 594 Q Sbjct: 575 TQ 576
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 52.3 bits (125), Expect = 2e-11 Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 5/92 (5%) Query: 42 MERKESVIFVAVEDGEYIGFTQLYPSFSSISMKELWILNDLFVQAAKRGAGTGKKLLEAA 101 +E + F+ + IG ++ +++ ++ D+ V R G G LL A Sbjct: 60 VEEEGKAAFLYYLENNCIGRIKIRSNWN-----GYALIEDIAVAKDYRKKGVGTALLHKA 114 Query: 102 KEFALENGAKGVKLQTEIDNLSAQRLYAENGY 133 E+A EN G+ L+T+ N+SA YA++ + Sbjct: 115 IEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 50.3 bits (120), Expect = 1e-10 Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 6/109 (5%) Query: 29 SYEDMNNRLQFVQMSPFDFLYVYEEEKTIFGLLGFRIRENLEDITRYGEISIISVDSTIR 88 YED + + +V+ ++Y E G + R N Y I I+V R Sbjct: 49 QYEDDDMDVSYVEEEG-KAAFLYYLENNCIGRIKIRSNWN-----GYALIEDIAVAKDYR 102 Query: 89 RKGIGHILMDYAEQLAKKHNCIGTWLVSGTKRVEAHPFYKKLGYEVNGY 137 +KG+G L+ A + AK+++ G L + + A FY K + + Sbjct: 103 KKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAV 151
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.0 bits (72), Expect = 0.002 Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 19/92 (20%) Query: 33 LIGANGAGKSTTIKTMLGLLVNVNGEISFGAKKNPYAYVPEHPTYYDYLTLWEHIELLMA 92 L G G GKST I T++GL + G K+ Y + + EL Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQI---------AGIV-AYEL--- 647 Query: 93 ARGNEVGSWERKAEELLHLF---RMDKYKHEY 121 +E+ ++ R E + F R D+Y+ Y Sbjct: 648 ---SEMTAFRRADAEAVKAFFSSRKDRYRGAY 676
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 28.5 bits (63), Expect = 0.019 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 9/91 (9%) Query: 35 DKPTSTAGQQNLESTSYTYEETNDRLTTDTFITYAMQEAEKQSMQKFGTKIGPVIEDEFK 94 D PT+T Q + + T D+LT + F E +K ++ G I E K Sbjct: 264 DDPTTTDPDQ---AANAAESATKDQLTQEAFKN---PENQKVNIDANGNAIP---SGELK 314 Query: 95 DVILPKIEEAIAELANDVPEESLQSLAISQK 125 D I+ +I + E +++++S A +Q+ Sbjct: 315 DDIVEQIAQQAKEAGEVARQQAVESNAQAQQ 345
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.4 bits (86), Expect = 3e-04 Identities = 50/335 (14%), Positives = 102/335 (30%), Gaps = 35/335 (10%) Query: 327 EQWHEEAMQNEQKAESLLKQIIAKKENIMNNFELAQEKYEVVKNKESERENVKKLVQRLE 386 E+ E A + E + +L + N + E E + N + + K + Sbjct: 53 EKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKA 112 Query: 387 -ELQPIIASLAEKQLNLQNAEIQIGKLKESMQNLDRQLEEHTNQKQLMTGELQQLEQALE 445 ++Q + A A+ + L+ A ++ L+ + +K + L+ Sbjct: 113 SKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST 172 Query: 446 QYVDKVEELTNMREDAKVLKQAYDVWQEKQKFEKEKEAAYSKMQLAVNAYENMERRWLSE 505 K++ L EK E + ++ A+N + + Sbjct: 173 ADSAKIKTLEA----------------EKAALEARQAELEKALEGAMNFSTADSAKIKTL 216 Query: 506 QAGILALHLHDGESCPVCGSTTHPKKATEQSGAIDENELNGLRDKKNIAEKLHVQLEEKW 565 +A AL K E++ N K E LE + Sbjct: 217 EAEKAAL--------------AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQ 262 Query: 566 NFYHHQYEQVIEEVKKRGYQSEELVETYSALVQKGKQLATEVNTLKAS-EETRKQIAVK- 623 E + + + L +AL + L + L A+ + R+ + Sbjct: 263 AELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASR 322 Query: 624 --IKSVEEKVDALQKQKREVETEQHRIEMDCMQLR 656 K +E + L++Q + E + + D R Sbjct: 323 EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASR 357
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.4 bits (110), Expect = 1e-07 Identities = 40/195 (20%), Positives = 82/195 (42%), Gaps = 8/195 (4%) Query: 206 MLGTKQVYLLFIMLFTSCMSGLYLIGMVKDIGVELVGLSAATAANAVAMVAIFNTLGRI- 264 M + + ++ + + G+ LI V + + S A+ ++A++ + Sbjct: 1 MKPNRPLIVILSTVALDAV-GIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFAC 59 Query: 265 --ILGPLSDKIGRLKIVTGTFVVMASSVLVLSFVDLNYGIYFVCVASVAFCFGGNITIFP 322 +LG LSD+ GR ++ + A +++ + +Y + VA G + Sbjct: 60 APVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRI--VAGITGATGAVAG 117 Query: 323 AIVGDFFGMKNHSKNYGIVYQGFGFGALAGSFIGALLGGFKP--TFMVIGLLCVVSFIIA 380 A + D ++++G + FGFG +AG +G L+GGF P F L ++F+ Sbjct: 118 AYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTG 177 Query: 381 MLIQAPNQKKEQEEE 395 + + K E+ Sbjct: 178 CFLLPESHKGERRPL 192 Score = 36.0 bits (83), Expect = 2e-04 Identities = 24/146 (16%), Positives = 59/146 (40%), Gaps = 13/146 (8%) Query: 8 PWLVVLGTVIVQMGLGTIYTWSLFNQPLVSKYGWSLNAVAITFSITSLSLA-FSTLFASK 66 L+ + ++ +G W +F + ++ W + I+ + + + + Sbjct: 213 AALMAVFFIMQLVGQVPAALWVIFGE---DRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 67 LQEKWGLRKLIMIAGLALGLGLILSSQASS----LILLYVLAGVVVGYADGTAYITSLSN 122 + + G R+ +M+ +A G G IL + A+ ++ +LA +G A ++ + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVD 329 Query: 123 LIKWFPERKGLIAGISVSAYGSGSLI 148 ER+G + G + S++ Sbjct: 330 -----EERQGQLQGSLAALTSLTSIV 350 Score = 32.1 bits (73), Expect = 0.004 Identities = 52/317 (16%), Positives = 108/317 (34%), Gaps = 38/317 (11%) Query: 63 FASKLQEKWGLRKLIMIAGLALGLGLILSSQASSLILLYVLAGVVVGYADGT-------- 114 L +++G R +++++ + + + A L +LY + +V G T Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLY-IGRIVAGITGATGAVAGAYI 120 Query: 115 AYITSLSNLIKWFPERKGLIAGISVSAYGSGSLIFKYVNAQLIESVGVSQAFIYWGLIVT 174 A IT + F G + +G G ++ V L+ F + Sbjct: 121 ADITDGDERARHF--------GFMSACFGFG-MVAGPVLGGLMGGFSPHAPFFAAAALNG 171 Query: 175 AMIVLGACLI---HQAADQSAVQETKTHEYTTKEMLGTKQVYLLFIMLFTSCMSGLYLIG 231 + G L+ H+ + +E + + G V L + F + G Sbjct: 172 LNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAA 231 Query: 232 MVKDIGVELVGLSAATAANAVAMVAIFNTLGRIIL-GPLSDKIGRLKIVTGTFVVMASSV 290 + G + A T ++A I ++L + ++ GP++ ++G + + + + Sbjct: 232 LWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGY 291 Query: 291 LVLSFVDLNYGIYFVCVASVAFCFGGNITIFPAIVGDFFGMKNHSKNYGIVYQGFGFGAL 350 ++L+F + + PA+ S+ QG G+L Sbjct: 292 ILLAFATRGW-----MAFPIMVLLASGGIGMPALQAML------SRQVDEERQGQLQGSL 340 Query: 351 A-----GSFIGALLGGF 362 A S +G LL Sbjct: 341 AALTSLTSIVGPLLFTA 357
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 322 bits (827), Expect = e-114 Identities = 163/261 (62%), Positives = 196/261 (75%), Gaps = 3/261 (1%) Query: 1 MNVGEFDGKTVLVTGAAQGIGSVVAKMFLERGATVIAVDQNGEGLNVLLNQNETRMKI-- 58 MN +GK +TGAAQGIG VA+ +GA + AVD N E L +++ + + Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 59 -FHLDVSDSNAVEDTVKRIENDIAPIDILVNVAGVLRMGAIHSLSDEDWNKTFSVNSTGV 117 F DV DS A+++ RIE ++ PIDILVNVAGVLR G IHSLSDE+W TFSVNSTGV Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 118 FYMSRAVSKHMMQRKSGAIVTVGSNAANTPRVEMAAYAASKAATTMFMKCLGLELAAYNI 177 F SR+VSK+MM R+SG+IVTVGSN A PR MAAYA+SKAA MF KCLGLELA YNI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 178 RCNLVSPGSTETEMQRLLWADENGAKNIIAGSQNTYRLGIPLQKIAQPSEITEAVLFLAS 237 RCN+VSPGSTET+MQ LWADENGA+ +I GS T++ GIPL+K+A+PS+I +AVLFL S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 238 DKASHITMHNLCVDGGATLGV 258 +A HITMHNLCVDGGATLGV Sbjct: 241 GQAGHITMHNLCVDGGATLGV 261
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 389 bits (1000), Expect = e-139 Identities = 176/306 (57%), Positives = 232/306 (75%), Gaps = 11/306 (3%) Query: 1 MAIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNI 60 MAIP+I Y+MP S++P+NKV+W PDP RAVLLIHDMQ YF+DA++ SP EL +NI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 KVIREKCKELGIPVVYTAQPGGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELTPDEDDIF 120 + ++ +C +LGIPVVYTAQPG Q + R LL DFWG G+ +GP ++KI+ EL P++DD+ Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLTACEAFMDGIQPFFVADAVAD 180 LTKWRYSAFK+TNLLE++ ++GRDQLII GIYAHIGCL+TACEAFM+ I+ FFV DAVAD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 FSLEHHKQALEYASNRCAVTTSTNSLLTELQGLKDD-----------DEITLQKVHELVA 229 FSLE H+ ALEYA+ RCA T T+SLL +LQ D + T + + + +A Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240 Query: 230 QLLREPVESVGTDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSP 289 +LL+E E + EDLL+RGLDSVRIM+LVE+WRREG E+TF +LAE PT+ +W +LL+ Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLTT 300 Query: 290 QTEHVL 295 +++ VL Sbjct: 301 RSQQVL 306
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 121 bits (304), Expect = 5e-32 Identities = 90/398 (22%), Positives = 172/398 (43%), Gaps = 14/398 (3%) Query: 20 FMAAMDATIVNVALQTISKELQVPPSAMGTVNVGYLVSLAVFLPISGWLGDRFGTKRIFL 79 F + ++ ++NV+L I+ + PP++ VN ++++ ++ + G L D+ G KR+ L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 80 TALFVFTTASALCGIANDITSLNIF-RIIQGAGGGLLTPVGMAMLFRTFSPEERPKISRF 138 + + S + + + SL I R IQGAG + M ++ R E R K Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 139 IVLPIAVAPAVGPIIGGFFVDQMSWRWAFYINLPFGIMALLFGLLFLKEHIEKSAGRFDS 198 I +A+ VGP IGG + W++ + +P + + L+ L + + G FD Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIH--WSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 199 LGFILSAPGFAMIIYALSQGPSRGWISTEIISTGIAGTVFITLFILVELKVKQPMLDLRL 258 G IL + G + ++ IS I + +F+ KV P +D L Sbjct: 202 KGIILMSVGIVFFMLF---------TTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 259 LKEPVFRKMSLISLFSSAGLLGMLFVFPLMYQNVIGVSALESG-LTTFPEAIGLMISSQI 317 K F L + G + + P M ++V +S E G + FP + ++I I Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 318 VPWSYKKLGARKVISIGLICTVIIFVLLSFVNHDTNPWQIRALLFGIGIFLGQSVGAVQF 377 + G V++IG+ + F+ SF+ T+ + ++F +G L + + Sbjct: 313 GGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFTKTVIST 371 Query: 378 SAFNNITPPSMGRATTIFNVQNRLGSAIGVAVLASILA 415 +++ G ++ N + L G+A++ +L+ Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 38.9 bits (90), Expect = 1e-05 Identities = 22/129 (17%), Positives = 48/129 (37%), Gaps = 23/129 (17%) Query: 53 RARFIIGCVISRLVLGKILSMSPVQVPIDRMCPVCKLQHGRPQLPEGMPQLSVSHSGEWV 112 +A + G + + L + + + V D+ +P P+G+ S+SH Sbjct: 47 KAEHLAGRIAAVHALRE-VGVRTVPGMGDK---------RQPLWPDGLFG-SISHCATTA 95 Query: 113 VVAFTKFAPVGVDVEQMNPNVDVMKMAEGVLTDIEKAQVMKLPNEQKIEGFLTYWTR--- 169 + ++ +G+D+E++ ++A ++ E+ Q Sbjct: 96 LAVISR-QRIGIDIEKIMSQHTATELAPSIIDSDER------QILQASLLPFPLALTLAF 148 Query: 170 --KEAVLKA 176 KE+V KA Sbjct: 149 SAKESVYKA 157
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 124 bits (313), Expect = 3e-41 Identities = 57/89 (64%), Positives = 74/89 (83%) Query: 2 NKTELIKNVAQSADISQKDASAAVQSVFDTIATALQSGDKVQLIGFGTFEVRERSARTGR 61 NK +LI VA++ ++++KD++AAV +VF +++ L G+KVQLIGFG FEVRER+AR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGEEIQIAAGKVPAFKAGKELKEAVK 90 NPQTGEEI+I A KVPAFKAGK LK+AVK Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 264 bits (677), Expect = 2e-88 Identities = 101/304 (33%), Positives = 150/304 (49%), Gaps = 19/304 (6%) Query: 110 TPNDPYYKN-QYGLQKIQAPLAWDSQRSDSSVKVAIIDTGVQGSHPDLSSKVIYGHDYVD 168 + G++ IQAP W+ R VKVA++DTG HPDL +++I G ++ D Sbjct: 13 IKQEQQVNEIPRGVEMIQAPAVWNQTRG-RGVKVAVLDTGCDADHPDLKARIIGGRNFTD 71 Query: 169 NDN----VSDDGNGHGTHCAGITGALTNNSVGIAGVAPHTSIYAVRVLDNQGSGTLDAVA 224 +D + D NGHGTH AG A T N G+ GVAP + ++VL+ QGSG D + Sbjct: 72 DDEGDPEIFKDYNGHGTHVAGTIAA-TENENGVVGVAPEADLLIIKVLNKQGSGQYDWII 130 Query: 225 QGIREAADSGAKVISLSLGAPNGGTALQQAVQYAWNKGSVIVAAAGNAGNTKAN-----Y 279 QGI A + +IS+SLG P L +AV+ A +++ AAGN G+ Y Sbjct: 131 QGIYYAIEQKVDIISMSLGGPEDVPELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGY 190 Query: 280 PAYYSEVIAVASTDQSDRKSSFSTYGSWVDVAAPGSNIYSTYKGSTYQSLSGTSMATPHV 339 P Y+EVI+V + + S FS + VD+ APG +I ST G Y + SGTSMATPHV Sbjct: 191 PGCYNEVISVGAINFDRHASEFSNSNNEVDLVAPGEDILSTVPGGKYATFSGTSMATPHV 250 Query: 340 AGVAAL-------LANQGYSNTQIRQIIESTSDKISGTGTYWKNGRVNAYKAVQYAKQLQ 392 AG AL + + ++ + + + + NG + + ++ Sbjct: 251 AGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKMEGNGLLYLTAVEELSRIFD 310 Query: 393 ENKA 396 + Sbjct: 311 TQRV 314
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.003 Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 10/65 (15%) Query: 17 LVGPSGSGKTTLIKLIAGINEATEGEVLVYNTNMPNLNEMKRIGYMAQADALYE--ELSA 74 L G G GK+TLI + G++ ++ ++ K YE E++A Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHF--------DIGTGKDSYEQIAGIVAYELSEMTA 652 Query: 75 YENAD 79 + AD Sbjct: 653 FRRAD 657
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 48.8 bits (116), Expect = 9e-09 Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 9/163 (5%) Query: 166 SFVRERLSGALERLLSTPIKRWEIVVGYIIGFGIFAFIQSIIIVSFSVYILDLYVAGSIW 225 +F R E +L T ++ +IV+G + A + I + + Y Sbjct: 90 AFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALG--YTQW--L 145 Query: 226 LTLLITCMLSLTAL---TLGTFLSAYANNEFQMIQFIPLVIVPQIFFSG-LFPIESMNKW 281 L +++LT L +LG ++A A + I + LVI P +F SG +FP++ + Sbjct: 146 SLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIV 205 Query: 282 LQMLGKLFPLTYGADAMRQVMIRNQGFTEIALDLTVLLFFSVL 324 Q + PL++ D +R +M+ + ++ + L + V+ Sbjct: 206 FQTAARFLPLSHSIDLIRPIMLGHPV-VDVCQHVGALCIYIVI 247
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 84.7 bits (209), Expect = 2e-22 Identities = 37/206 (17%), Positives = 82/206 (39%), Gaps = 12/206 (5%) Query: 16 DKRNERQMRILEAAVDMFGEKGYASTSTSEIAKRAGVAEGTIFRYYKTKKDLLLAVVMPT 75 + E + IL+ A+ +F ++G +STS EIAK AGV G I+ ++K K DL Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE----- 61 Query: 76 LMKFAAPFFVQAFAKEIFKSEYESYEGLLRVVIHNRFDFA---KKHFPMIKILIQEVPFH 132 + + + + E +LR ++ + + ++ +++I+ + F Sbjct: 62 IWELSESNIGELEL-EYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 133 PELK--NEIQQLVETELLLHFKKLIEKFQEKGKIIEMPPATVLRLTLSAVFGLLLTRFLL 190 E+ + Q+ + E ++ ++ E + + + L+ +L Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 191 LPEEKWDDETEIENTIQFILYGLTPR 216 P+ D + E + + +L Sbjct: 181 APQSF-DLKKEARDYVAILLEMYLLC 205
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 34.4 bits (79), Expect = 0.001 Identities = 22/80 (27%), Positives = 33/80 (41%), Gaps = 6/80 (7%) Query: 97 EEGIVFIGPSEEIITKMGSKIESRIAMQA--ADVPVVPGITTNIETAEEAIEIAKQIGYP 154 EGIV + P+EE + K + + A + P T + +E+A IG P Sbjct: 224 IEGIVIVNPTEEEVKAYEEKRAAFEKQKQEWAKLVGEPSTTKD----GAHVELAANIGTP 279 Query: 155 LMLKASAGGGGIGMQLMETE 174 + GG G+ L TE Sbjct: 280 KDVDGVLANGGEGIGLYRTE 299
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 1e-04 Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 42 IVSEEAGTVMKINVQEGDFVNEGDVLLEIE 71 I E V +I V+EG+ V +GDVLL++ Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLT 128
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 145 bits (368), Expect = 2e-40 Identities = 91/406 (22%), Positives = 166/406 (40%), Gaps = 16/406 (3%) Query: 19 ILMASMDNTIVVTAMGTIVGDLGGLENFV-WVVSAYMVAEMAGMPIFGKLSDMYGRKRFF 77 + ++ ++ ++ I D WV +A+M+ G ++GKLSD G KR Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 78 IFGLIVFMVGSALCGTAENITQLGIY-RAIQGIGGGALVPIAFTIVFDIFPPEKRGKMGG 136 +FG+I+ GS + + L I R IQG G A + +V P E RGK G Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFG 142 Query: 137 LFGAVFGLSSIFGPLLGAYITDYISWHWVFYINLPLGVLALIFITFFYKESRVHRKQKID 196 L G++ + GP +G I YI HW + + +P+ + + + V K D Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYI--HWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFD 200 Query: 197 WSGAITLVGAVICLMFALELGGQKYDWDSTFILSLFVGFAILIISFIFIERKVEEPIISF 256 G I + ++ M L Y S + + + F+ RKV +P + Sbjct: 201 IKGIILMSVGIVFFM----LFTTSYSI------SFLIVSVLSFLIFVKHIRKVTDPFVDP 250 Query: 257 EMFKQRLFGMSTIIALCYGAAFMSATVYIPLFIQGVYGGSATNSG-LLLLPMMLGSVVTA 315 + K F + + +P ++ V+ S G +++ P + ++ Sbjct: 251 GLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFG 310 Query: 316 QLGGFLTTKLSYRNIMIISAVIMLIGLFLLSALTPETSRALLTVYMIIIGFGVGFSFSVL 375 +GG L + ++ I + + FL ++ ET+ +T+ ++ + G+ F+ +V+ Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVS-FLTASFLLETTSWFMTIIIVFVLGGLSFTKTVI 369 Query: 376 SMAAIHNFGMEQRGSATSTSNFIRSLGMTLGITIFGMIQRTGFQDQ 421 S + ++ G+ S NF L GI I G + DQ Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQ 415
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 1e-05 Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 9/78 (11%) Query: 46 YEEQACIGIEIIGAN---KAKIRHIAVIPQYRHKGIALQMI---KEVVRIHQLTYLEAET 99 Y E CIG I +N A I IAV YR KG+ ++ E + + L ET Sbjct: 71 YLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLET 130 Query: 100 DD---EAVEFYKRIGFQV 114 D A FY + F + Sbjct: 131 QDINISACHFYAKHHFII 148
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 28.4 bits (63), Expect = 0.039 Identities = 10/45 (22%), Positives = 23/45 (51%), Gaps = 4/45 (8%) Query: 12 FFFAFTFVLNRAMDLEGGSWI-WSASLRY---YFMVPMLLLIVMY 52 F A ++L +++L + W L Y+++P+L+ + M+ Sbjct: 432 IFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMF 476
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 43.0 bits (101), Expect = 9e-08 Identities = 19/90 (21%), Positives = 35/90 (38%), Gaps = 5/90 (5%) Query: 57 FGAFNEDHQLVGVVTLLTEEKEAYKHKGHIVAMYVDASNQRSGLARELICKAIERAKEMN 116 F + ++ +G + + + + I + V ++ G+ L+ KAIE AKE + Sbjct: 68 FLYY-LENNCIGRIKI----RSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122 Query: 117 LEQLTLGVVSTNEPAKRLYESMGFKTYGIE 146 L L N A Y F ++ Sbjct: 123 FCGLMLETQDINISACHFYAKHHFIIGAVD 152
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 25.0 bits (54), Expect = 0.046 Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 2/61 (3%) Query: 28 KDEKEPDPTEEPSEQRQEEKNEKQD-PAKEQNNELNK-KDEQEPDPTEEPSEEQKKKKEN 85 ++ E D TE ++ R+ K K + A Q NE+ + E + T E E +KE Sbjct: 1051 VEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEE 1110 Query: 86 E 86 + Sbjct: 1111 K 1111
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 52.7 bits (126), Expect = 8e-11 Identities = 43/158 (27%), Positives = 71/158 (44%), Gaps = 19/158 (12%) Query: 2 KKALLVIDVQ---AGMYTAGMPVHNGEKFLETLQELIGECRSNDIPVIYVQHNGPKDHPL 58 + LL+ D+Q +TAG + +++L +C IPV+Y G + +P Sbjct: 30 RAVLLIHDMQNYFVDAFTAGASPV--TELSANIRKLKNQCVQLGIPVVYTAQPGSQ-NPD 86 Query: 59 EKG--TDGW-----------KIHAAIAPLEGECVVEKTTPDSFHKTNLKEVLQDKGIDHV 105 ++ TD W KI +AP + + V+ K +F +TNL E+++ +G D + Sbjct: 87 DRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQL 146 Query: 106 IISGMQTQYCVDTTTRRACSEGYKITLVSDAHSTFDTE 143 II+G+ T A E K V DA + F E Sbjct: 147 IITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLE 184
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 35.7 bits (82), Expect = 4e-05 Identities = 19/89 (21%), Positives = 30/89 (33%), Gaps = 14/89 (15%) Query: 78 VDSESKTLYGYEESQNVWG-------------MDQFIGEPTYWGKGIGTKFVKAAITYIL 124 V+ E K + Y N G ++ Y KG+GT + AI + Sbjct: 60 VEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAK 119 Query: 125 SEMGAEAIAMDPKVNNERAIKCYEKCGFK 153 E + ++ + N A Y K F Sbjct: 120 -ENHFCGLMLETQDINISACHFYAKHHFI 147
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 53.5 bits (128), Expect = 1e-09 Identities = 45/216 (20%), Positives = 73/216 (33%), Gaps = 4/216 (1%) Query: 146 PVEKKADEKTKQVAKVQKSVKAKEEAKTQKITKAKETIKPKEEVKVQEVVKPKEEVKVQE 205 V+ + SV + E + P + E V E K + Sbjct: 991 TVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA--ENSKQES 1048 Query: 206 VVKPKEEVKVQEVAKPKEEVKVQEVAKPKEEVKVQEVAKPKEEVKVQEVVKPKEEVKVQE 265 K E E EV + + K + EVA+ E K + + KE V++ Sbjct: 1049 KTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEK 1108 Query: 266 VAKAKEEA-KAQEIAKAKEEAKAQEIAKAKEEAKAQEIAKAKEEAKAQEIAKAKEEAKAR 324 KAK E K QE+ K + ++ +++ E A+ + + +++ A Sbjct: 1109 EEKAKVETEKTQEVPKVTSQVSPKQ-EQSETVQPQAEPARENDPTVNIKEPQSQTNTTAD 1167 Query: 325 EALKAKEESKNNAQSAKRELTVVATAYTADPSENGT 360 AKE S N Q TV + EN T Sbjct: 1168 TEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203 Score = 44.7 bits (105), Expect = 7e-07 Identities = 36/223 (16%), Positives = 79/223 (35%), Gaps = 11/223 (4%) Query: 132 KTAYVNVSFLSSKAPVEKKADEKTKQVAKVQKSVKAKEEAKTQKITKAKETIKPKEEVKV 191 +T ++ +K ++ + + V + ++ + T+ E + E K Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKE 1094 Query: 192 QEVVKPKEEVKVQEVVKPKEEVKVQEVAKPKEEVKVQEVAKPKEEVKVQEVAKPKEEVKV 251 + + KE V++ K K E K +E KV PK+E + + V E + Sbjct: 1095 TQTTETKETATVEKEEKAKV-----ETEKTQEVPKVTSQVSPKQE-QSETVQPQAEPARE 1148 Query: 252 QEVVKPKEEVKVQEVAKAKEEAKAQEIAKAKEEA----KAQEIAKAKEEAKAQEIAKAKE 307 + +E + Q A E A+E + E+ + E + Sbjct: 1149 NDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQ 1208 Query: 308 EAKAQEIAKAKEEAKAREALKAKEESKNNAQSAKRELTVVATA 350 E + K + + R ++++ + A ++ + + VA Sbjct: 1209 PTVNSESSN-KPKNRHRRSVRSVPHNVEPATTSSNDRSTVALC 1250 Score = 42.0 bits (98), Expect = 5e-06 Identities = 47/286 (16%), Positives = 88/286 (30%), Gaps = 30/286 (10%) Query: 128 EYKGKTAYVNVSFLSSKAPVEKKADEKTKQVAKVQKSVK------AKEEAKTQKITKAKE 181 E ++ +A KA+ +T +VA+ K KE A +K KAK Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 182 TIKPKEEV-KVQEVVKPK----EEVKVQEVVKPKEEVKVQEVAKPKEEVKVQEVAKPKEE 236 + +EV KV V PK E V+ Q + + V + + +P +E Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKE 1174 Query: 237 VKVQEVAKPKEEVKVQEVVKPKEEVKVQEVAKAKEEAKAQEIAKAKEEAKAQEIAK--AK 294 V +P E E + E + + + + Sbjct: 1175 TS-SNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHN 1233 Query: 295 EEAKAQEIAKAKEEAKAQEIAKAKEEAKAREALKAKEESKNNAQSAKRELTVVATA---- 350 E A + + KA+ + N ++ + ++ + Sbjct: 1234 VEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293 Query: 351 ---YTADPSENGTYGG---------RVLTAMGHDLTANPNMRIIAV 384 + ++ S N Y T +G D T + N+++ V Sbjct: 1294 YNVWVSNTSMNKNYSSSQYRRFSSKSTQTQLGWDQTISNNVQLGGV 1339
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 26.9 bits (59), Expect = 0.038 Identities = 8/25 (32%), Positives = 13/25 (52%) Query: 17 ISSGTIKIHFTNFHDSVDYDRQLYI 41 +S+G+ I+ HD V YD+ Sbjct: 625 LSAGSANIYAGKGHDVVYYDKTDTG 649
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 31.7 bits (72), Expect = 0.004 Identities = 14/55 (25%), Positives = 21/55 (38%) Query: 74 GKISSYTAGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENRVQLDDSIE 128 G++ +A T ++D RF + S K VL V QL+ I Sbjct: 38 GRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIH 92
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 29.3 bits (65), Expect = 0.029 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 3/37 (8%) Query: 310 KHLQNVLKILASISDQDTPVSSSYFYTAGFRRKELDA 346 KHL+ +L++L ++S Q PVSS T GF + +A Sbjct: 567 KHLETLLEVLVTLSQQGQPVSSE---TYGFLNRLTEA 600
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 42.9 bits (101), Expect = 1e-06 Identities = 33/156 (21%), Positives = 62/156 (39%), Gaps = 20/156 (12%) Query: 15 IIGKDESI----ELAAIALIAKGHILLEDVPGTGKTTLAKSL---AKSVDAKFQRIQFTA 67 ++G+ ++ + A + +++ GTGK +A++L K + F I A Sbjct: 139 LVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAA 198 Query: 68 DTLPGDVIGLEYFNVKESDF----KTRLGPI-FAN--IVLVDEINRAVPRTQSSLLEVME 120 +P D+I E F ++ F G A + +DEI Q+ LL V++ Sbjct: 199 --IPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQ 256 Query: 121 ERTVTIAKQTHSLPEPFLVIATQN-PLESA---GTF 152 + T + ++A N L+ + G F Sbjct: 257 QGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLF 292
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 635 bits (1640), Expect = 0.0 Identities = 223/647 (34%), Positives = 343/647 (53%), Gaps = 13/647 (2%) Query: 1 MTTINIEIVAHVDAGKTSLTERILYETNVIKEVGRVDSGSTQTDSMELERQRGITIKASV 60 M INI ++AHVDAGKT+LTE +LY + I E+G VD G+T+TD+ LERQRGITI+ + Sbjct: 1 MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGI 60 Query: 61 VSFFIDDIKVNVIDTPGHADFIAEVERSFRVLDGAILVISAVEGVQAQTKILMQTLQKLN 120 SF ++ KVN+IDTPGH DF+AEV RS VLDGAIL+ISA +GVQAQT+IL L+K+ Sbjct: 61 TSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMG 120 Query: 121 IPTILFVNKIDRTGANTEKVVKQIKTILSNETFPFYSVQNEGTKEARIIEYKSYDDCIER 180 IPTI F+NKID+ G + V + IK LS E V E + + + + + Sbjct: 121 IPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKV--ELYPNMCVTNF-TESEQWDT 177 Query: 181 LAPYNESLLESFVNNEIVTDTLLREELEKQIQQANLYPIFFGSALTGIGVTELLEDIPAL 240 + N+ LLE +++ + + L +E + +L+P++ GSA IG+ L+E I Sbjct: 178 VIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNK 237 Query: 241 LPANNPSQDEELSGIVFKIEREPSGEKIAYVRVFSGTLHVRKYVHIQRDGSLPHKEKIKK 300 ++ EL G VFKIE +++AY+R++SG LH+R V I K KI + Sbjct: 238 FYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKE----KIKITE 293 Query: 301 MCIFHNGNAVQTSTVPSGDFCKVWGLNNIKIGDIIGERT--DYIKDIHFAEPQMEAAINA 358 M NG + SG+ + +K+ ++G+ + I P ++ + Sbjct: 294 MYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEP 352 Query: 359 VPKERIHDLYAALMELCEADPLIKVWKDDIHNELYIRLFGEVQKEVIETTLYEKYNLQVT 418 ++ L AL+E+ ++DPL++ + D +E+ + G+VQ EV L EKY++++ Sbjct: 353 SKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIE 412 Query: 419 FSSTRVVCMEKPIGIGNSVEVMGEKANPFYATIGFKVERGELNSGITYKLGVELGSLPLA 478 V+ ME+P+ + NPF+A+IG V L SG+ Y+ V LG L + Sbjct: 413 IKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQS 472 Query: 479 FHKASEDTVFQTLKQGLYGWEVTDISVTLTHTGYASPVTTASDFRNLTPLVLMDALKQAE 538 F A + + +QGLYGW VTD + + Y SPV+T +DFR L P+VL LK+A Sbjct: 473 FQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAG 532 Query: 539 TYVYEPVNEFELTVPEHAISTAMYKLAAILATFAEPIFNNDSYQLTGSLPVAKTESFKRM 598 T + EP F++ P+ +S A A + N+ L+G +P + ++ Sbjct: 533 TELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSD 592 Query: 599 LHSFTEGEGVFTTKPAGFTKLMAPLPTRKRVDYNPLNRKDYLLHVLK 645 L FT G V T+ G+ + R P +R D + ++ Sbjct: 593 LTFFTNGRSVCLTELKGYHVTTGEPVCQPR---RPNSRIDKVRYMFN 636
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 34.0 bits (78), Expect = 0.001 Identities = 30/151 (19%), Positives = 52/151 (34%), Gaps = 46/151 (30%) Query: 94 DTLYGIGSTSKVYTAAAVMKLVDEGKVDLDASVTRYIPEFKMKDERYKRITPRMLLNHSS 153 D + + ST KV AV+ VD G L+ + + L+++S Sbjct: 59 DERFPMMSTFKVVLCGAVLARVDAGDEQLERKIH---------------YRQQDLVDYSP 103 Query: 154 GLQGSTLNNAFLFKDNDVYAHDILLQQLSNQNLKADPGAFSVYCNDGFTLAEILVERVSG 213 + A + + +L A ++ +D + A +L+ V G Sbjct: 104 VSE-------------KHLADGMTVGELC---------AAAITMSDN-SAANLLLATVGG 140 Query: 214 M-SFTEFLHQKFTEPLKLNHTITSQDKWEDE 243 T FL Q + +T D+WE E Sbjct: 141 PAGLTAFLRQ-------IGDNVTRLDRWETE 164
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 26.8 bits (59), Expect = 0.021 Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 8/46 (17%) Query: 38 IISVLCSQRATTQKELAEAIDKD-----QTTVVRMIQSMERKGIVK 78 I ++ + TQ EL + + KD Q TV R I+ + +VK Sbjct: 10 IREIITANEIETQDELVDILKKDGYNVTQATVSRDIKEL---HLVK 52
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 32.9 bits (75), Expect = 0.002 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 13/64 (20%) Query: 262 IITFLIAGHETTSGLLSFAIYFLLKNPDKLKKAYEEVDRVLTDSTPTYQQVMKLKYIRMI 321 + FLI ++FAI+ +K +KL + EE PT ++V+ L IR + Sbjct: 82 VFDFLI---------VAFAIFMAIKLINKLNRKKEEPA---AAPAPTKEEVL-LTEIRDL 128 Query: 322 LNES 325 L E Sbjct: 129 LKEQ 132
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 128 bits (323), Expect = 2e-34 Identities = 86/362 (23%), Positives = 165/362 (45%), Gaps = 19/362 (5%) Query: 14 MLVILFIGAFVSFLNNSLLNVALPSIMKDLDIKDYSTIQWLSTGYMLVSGILIPASAFLI 73 +L+ L I +F S LN +LNV+LP I D + ST W++T +ML I L Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPAST-NWVNTAFMLTFSIGTAVYGKLS 73 Query: 74 TRFSNRSLFITSMMIFTLGTALAAVAPN-FGLLLTGRMVQAAGSSVMGPLLMNIMLVSFP 132 + + L + ++I G+ + V + F LL+ R +Q AG++ L+M ++ P Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 133 REKRGTAMGIFGLVMITAPAIGPTLSGYIVEYYDWRLLFEMILPLAIISLLLGIWKSENV 192 +E RG A G+ G ++ +GP + G I Y W L L + ++ + + Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL-----LIPMITIITVPFLMKL 188 Query: 193 MRQNKNAK--LDYLSLLLSSIGFGGLLYGFSSASSDGWTNKVVVTTLILGAIALIAFIIR 250 +++ K D ++L S+G + +S S ++ LI+ ++ + F+ Sbjct: 189 LKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYS---------ISFLIVSVLSFLIFVKH 239 Query: 251 QLKMNEPLLDLRVYKYPMFALASVIAIVNAVAMFSGMILTPAYVQNVRGISPLSSG-LMM 309 K+ +P +D + K F + + + + + + P +++V +S G +++ Sbjct: 240 IRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVII 299 Query: 310 LPGAVIMGIMSPITGKLFDKYGPRILGIVGLSITAVSTYMLANLQLDSSHTHTILIYTLR 369 PG + + I I G L D+ GP + +G++ +VS + L +S TI+I + Sbjct: 300 FPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVL 359 Query: 370 MF 371 Sbjct: 360 GG 361
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 99.1 bits (247), Expect = 3e-26 Identities = 31/112 (27%), Positives = 57/112 (50%) Query: 2 RVLIVEDEQDLQNILVKRLNAEHYSVDACGNGEDALDYINMATYDLIVLDIMIPGINGLQ 61 +L+ +D+ ++ +L + L+ Y V N +I DL+V D+++P N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLQKLRADNHTTSVLLLTAKDTIDDRVKGLDLGADDYLVKPFAFDELLARIR 113 +L +++ VL+++A++T +K + GA DYL KPF EL+ I Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 5e-05 Identities = 17/102 (16%), Positives = 34/102 (33%), Gaps = 22/102 (21%) Query: 359 NIFTNSIKFSNEGGTIEFFVEELESSVIISISDNGIGMEKEEMDRIFDRFYKVDTARARN 418 N + I +GG I + +V + + + G K Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK----------------- 308 Query: 419 VEGSGLGLSIVQKIVELHNGN---VSVYSTKGEGTTVRVELP 457 E +G GL V++ +++ G + + +G V +P Sbjct: 309 -ESTGTGLQNVRERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.2 bits (203), Expect = 2e-20 Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 1/123 (0%) Query: 1 MKMIHILLADDDKHIRELLHYHLQKEGFKVFEAEDGKVAQEVLEKENIHLAIVDIMMPFV 60 M IL+ADDD IR +L+ L + G+ V + + + L + D++MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGYTLCEEIRK-YHDIPVILLTAKDQLVDKEKGFISGTDDYIVKPFEPAEVIFRMKALLR 119 + + L I+K D+PV++++A++ + K G DY+ KPF+ E+I + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RYQ 122 + Sbjct: 121 EPK 123
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.8 bits (85), Expect = 9e-06 Identities = 28/136 (20%), Positives = 48/136 (35%), Gaps = 15/136 (11%) Query: 1 MTTHIEKCTLKDIHKLQEISYETFNETF-KHQNSPENMHHYLEKAFNLKQLEKE------ 53 M + +KD +K E + F +N KQ E + Sbjct: 1 MIMKMTHLNMKDFNKPNE-PFVVFGRMIPAFENGVWTYTEERFSKPYFKQYEDDDMDVSY 59 Query: 54 LSNISSQFFFVYFNDEIAGYLKINTDDAQSEEIGDESLEVERIYIKSSFQKHGLGKYLLN 113 + F Y + G +KI ++ + +E I + ++K G+G LL+ Sbjct: 60 VEEEGKAAFLYYLENNCIGRIKIRSN-------WNGYALIEDIAVAKDYRKKGVGTALLH 112 Query: 114 NAIEIAIANNKKNIWL 129 AIE A N+ + L Sbjct: 113 KAIEWAKENHFCGLML 128
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.0 bits (88), Expect = 4e-06 Identities = 25/122 (20%), Positives = 48/122 (39%), Gaps = 13/122 (10%) Query: 21 IPAYEIEAKYINSTAIPRLY--------DTIADIQSCDEIFYGYFYEDTLAGFISFKID- 71 IPA+E + Y ++ ++ + + Y+ E+ G I + + Sbjct: 27 IPAFENGVWTYTEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNW 86 Query: 72 KEEVDIHRLVVSPDHFHKGIATKLLLYIFDMFSSSKTY---IVQTGKENTPALSLYKKHG 128 I + V+ D+ KG+ T LL + ++ + +++T N A Y KH Sbjct: 87 NGYALIEDIAVAKDYRKKGVGTALLHKAIE-WAKENHFCGLMLETQDINISACHFYAKHH 145 Query: 129 FI 130 FI Sbjct: 146 FI 147
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 58.3 bits (141), Expect = 1e-11 Identities = 41/314 (13%), Positives = 96/314 (30%), Gaps = 11/314 (3%) Query: 7 PIRFMLISSFFMSFGYFAVYAFLAIYLLTFLHFSAVQ--VGTVLTVMTITSRIIPLFSGL 64 P+ +L + + G + L L +H + V G +L + + G Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 65 IADKIGYIIMMIAGLFLRGIGFIALGICSDFYTISISSALIGFGTAFYEPAARAIFGSQP 124 ++D+ G +++ L + + + + + I + G A A I Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITD 125 Query: 125 AHTRKNLFTYLNLSFNCGAIMGPIAGGFLLLLDPIYAFSLTGSLMLIFAFIFYLLKDHFQ 184 R F +++ F G + GP+ GG + P F +L + L Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESH 185 Query: 185 VTTENTSITLGIQAILQNKSFLLFSFIMIFFYIMFT-QLTVALPLHMKNISNSNQLA--- 240 + + + + + + F QL +P + I ++ Sbjct: 186 KGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDA 245 Query: 241 ---TLVITINAITGVIFMVLFRKLFLKY-NTLSFIKYGVLLMSISFLLIPLFQHPYWLFI 296 + + I + + + G++ ++L+ F W+ Sbjct: 246 TTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILL-AFATRGWMAF 304 Query: 297 CVIFFTIGETLVLP 310 ++ + +P Sbjct: 305 PIMVLLASGGIGMP 318
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 36.4 bits (84), Expect = 4e-05 Identities = 24/133 (18%), Positives = 49/133 (36%), Gaps = 21/133 (15%) Query: 78 YMKQKKWEEAKEALQKSISIQPSDEAYHNV-AVAHYNLGELEEASEFFLRVA----GDSD 132 + K+E+A + Q + D + +G+ + A + A + Sbjct: 46 QYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPR 105 Query: 133 YIMYSYVKCLIDLGRTKEAKEKLDAFNRESDNFLGEMMVAD------LYVELNCYKEAIE 186 + ++ CL+ G EA+ L L + ++AD L ++ EAI+ Sbjct: 106 FPFHAAE-CLLQKGELAEAESGLF---------LAQELIADKTEFKELSTRVSSMLEAIK 155 Query: 187 WFEKGYKECWKSP 199 ++ EC +P Sbjct: 156 LKKEMEHECVDNP 168 Score = 30.7 bits (69), Expect = 0.004 Identities = 16/96 (16%), Positives = 33/96 (34%), Gaps = 2/96 (2%) Query: 30 SRDVQSLNNLAWMYFYEEENDEKALELIGEVVKLNPSSYFPYNILRDIYMKQKKWEEAKE 89 S ++ L +LA Y+ E A ++ + L+ + L +++ A Sbjct: 33 SDTLEQLYSLA-FNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIH 91 Query: 90 ALQKSISIQPSDEAYH-NVAVAHYNLGELEEASEFF 124 + + + + + A GEL EA Sbjct: 92 SYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGL 127
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 27.4 bits (61), Expect = 0.005 Identities = 13/69 (18%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Query: 10 IGNIFWIIVFGIWAAIIWL--RDVDGAGVIQTPEIKSISLIVI---LIAFIIPVFFQVIW 64 + + WII+ G ++ L ++ + ++ + +I ++ I F+ Sbjct: 150 LSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVICTVGFVVISIADYAFEYYQ 209 Query: 65 LIINLRMSK 73 I L+MSK Sbjct: 210 YIKELKMSK 218
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.2 bits (161), Expect = 1e-15 Identities = 27/168 (16%), Positives = 57/168 (33%), Gaps = 22/168 (13%) Query: 8 KEKKKRAIKEAAFLLFSERGFNEVKIEHIAKEANVSQVTIYNHFGSKDALFRELIQEFII 67 ++ ++ I + A LFS++G + + IAK A V++ IY HF K LF E+ + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL--- 65 Query: 68 CEFQYYKELAEEKLP-------------FHDMMQKMIVRKMNTGGLFQPDMLLQMMQRDE 114 EL E +++ + + + + + Sbjct: 66 -SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 115 ILREFIYSYQNEKILPWYLEILERAQRNNEI----NPHLTKEMMLLYI 158 ++++ + E + L+ + +M YI Sbjct: 125 VVQQAQRNLCLE-SYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.3 bits (71), Expect = 0.015 Identities = 12/49 (24%), Positives = 22/49 (44%), Gaps = 1/49 (2%) Query: 455 INTEKAKLADIFKNEEINTIIYAIGGGVGNEFDVEDINYDKVVIMTDAD 503 ++ EKA+ + ++ TI A+GG N+F + + DA Sbjct: 730 VDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKK-LYVQADAK 777
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 66.2 bits (161), Expect = 4e-14 Identities = 33/166 (19%), Positives = 62/166 (37%), Gaps = 38/166 (22%) Query: 134 NKAYIVTNNHVVDGANKLAVKLS------------DGKKVDAKLVGKDPWLDLAVVEI-- 179 K ++TN HVVD + L +G ++ DLA+V+ Sbjct: 110 GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSP 169 Query: 180 --DGANVN---KVATLGDSSKIRAGEKAIAIGNPLGFDG---SVTEGIISSKEREIPVDI 231 ++ K AT+ ++++ + + G P ++G I+ + E Sbjct: 170 NEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEA---- 225 Query: 232 DGDKRADWNAQVIQTDAAINPGNSGGALFNQNGEIIGINSSKIAQQ 277 +Q D + GNSG +FN+ E+IGI+ + + Sbjct: 226 ------------MQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNE 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 2e-22 Identities = 34/164 (20%), Positives = 76/164 (46%), Gaps = 16/164 (9%) Query: 4 TVLLVEDERRLREIVSDYFRNEGFEVIEAEDGKKALELFAEHEIDLIMLDIMLPEIDGWS 63 T+L+ +D+ +R +++ G++V + A + DL++ D+++P+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 VCRRIRKESA-VPIIMLTARSDEDDTLLGFELGADEYVTKPFSPKVLVA---RAKTLLKR 119 + RI+K +P+++++A++ + E GA +Y+ KPF L+ RA KR Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 120 ADGVVGVAEENAMSLAGIE------------VNRLSRTVLVDGE 151 + ++ M L G + + T+++ GE Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGE 168
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 94.7 bits (235), Expect = 1e-25 Identities = 68/248 (27%), Positives = 113/248 (45%), Gaps = 16/248 (6%) Query: 3 KYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSE-----EKVNELQKEWGEVIPVQ-AN 56 K A +TG + GIG A+++ L G + N E + + E P + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 57 LASSDGAEQLWEQIEHPLDAIIYAAGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMAL 116 A+ D E+ P+D ++ AG GL+ ++++E + ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 117 PSMIQRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALAKEVSLSGIRVNAVAPG 176 M+ RRSG+IV V S + + Y+ K A + K L E++ IR N V+PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 177 AIETEM-LNVFSEEDKNE-----IAEE----IPLGRLGLPEEVAKTVSFLVSPGASYITG 226 + ET+M +++++E+ E E IPL +L P ++A V FLVS A +IT Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 227 QIIGVNGG 234 + V+GG Sbjct: 249 HNLCVDGG 256
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 31.0 bits (70), Expect = 0.007 Identities = 9/14 (64%), Positives = 10/14 (71%) Query: 162 VPGLSDIPVIGKIF 175 VP L DIP IG +F Sbjct: 475 VPLLGDIPYIGALF 488
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 64.3 bits (156), Expect = 2e-13 Identities = 76/329 (23%), Positives = 130/329 (39%), Gaps = 55/329 (16%) Query: 1 MKKKTGLLLSLTLAAS---AVLGACGNSDKASSDKKE----------------------- 34 MKK +LL L+ A+ AV +CGN+D+++ KE Sbjct: 1 MKKSKKILLGLSPIAAILPAVAVSCGNNDESNISFKEKDISKYTTTNANGKQVVKNAELL 60 Query: 35 -FKVGMVTDVGGVDDKSFNQSAWEGLTKFGKDNNLKKNEGYRYLQSSKDADYIPNLTKFA 93 K ++TD G +DDKSFNQSA+E L K ++ N +++ Sbjct: 61 KLKPVLITDEGKIDDKSFNQSAFEALKAINKQTGIEIN------NVEPSSNFESAYNSAL 114 Query: 94 KDHYNTTFGIGYLMEKSIEKVAEQYPKE----QFAIV----DTVVEKPNVTSITFKDHEG 145 + G+ ++SI++ + + +E Q I+ D E S+ F E Sbjct: 115 SAGHKIWVLNGFKHQQSIKQYIDAHREELERNQIKIIGIDFDIETEYKWFYSLQFNIKES 174 Query: 146 SFLVG-AVAAMTTKSNK----VGFVGGVKSPLITKFESGFKAGAKAVN---PNIEIVSQY 197 +F G A+A+ ++ ++ V GG P +T F GF G N + +I Sbjct: 175 AFTTGYAIASWLSEQDESKRVVASFGGGAFPGVTTFNEGFAKGILYYNQKHKSSKIYHTS 234 Query: 198 ADAFDK-----PEKGSVLASAMYGGGVDVIYHASGATGNGVFTEAKNRKKKGENVWVIGV 252 D + +V+ + + DV Y+ + + + +VIGV Sbjct: 235 PVKLDSGFTAGEKMNTVINNVLSSTPADVKYNPHVILSVAGPATFETVRLANKGQYVIGV 294 Query: 253 DRDQNQEGMPENVTLTSMVKRVDVAVAKV 281 D DQ + + LTS++K + AV + Sbjct: 295 DSDQGMIQDKDRI-LTSVLKHIKQAVYET 322
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.1 bits (75), Expect = 0.005 Identities = 30/168 (17%), Positives = 54/168 (32%), Gaps = 19/168 (11%) Query: 210 RAKRTAEQTEKKKTTRSTRSKRATEQEEIIEPMEEISIDPPIISNFTENYPVNEQEDKRI 269 + AE ++++ T + ATE + + + N N Q ++ Sbjct: 1036 TTETVAENSKQESKTVEKNEQDATETT---------AQNREVAKEAKSNVKANTQTNEVA 1086 Query: 270 EVEQEELITSPF-IEEAPPVEEPKKKRGEKIVESLEGETQAPPMQFSNVENKDYKLPALD 328 + E T +E VE+ +K + E +TQ P S V K + + Sbjct: 1087 QSGSETKETQTTETKETATVEKEEKAKVET------EKTQEVPKVTSQVSPKQEQSETVQ 1140 Query: 329 ILKFPKNKQVTNENAEIYENARKLERTFQSFGVKAKVTKVHRGPAVTK 376 P + N + + T AK T + VT+ Sbjct: 1141 PQAEPARENDPTVNI---KEPQSQTNTTADTEQPAKETSSNVEQPVTE 1185
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 36.0 bits (83), Expect = 3e-04 Identities = 18/151 (11%), Positives = 44/151 (29%), Gaps = 1/151 (0%) Query: 133 EQFNHLLMYYRTYGIQISINKVGTGTSN-LERISVLAPDILKVDLTNLRQTALLQSYQDI 191 + + +K+ TG S L +DL+ +++ +D+ Sbjct: 179 DMIENFTKENSLQLNDNIFSKIFTGVSKTLSSEICFRLKNNSIDLSLSNLKEIVEVCKDL 238 Query: 192 LYSLSLLARRIGATLLYEEIDAFYQLQYAWKNGGRYYQGNYLKECLPDFIETNVLKERLG 251 + FY L K + Q + + L +F +RL Sbjct: 239 FKEIQSNKFEFNCYTKNNSFVGFYCLNLMSKEDYKKIQYDSSSKLLENFYYAKDKSDRLK 298 Query: 252 NECHQFIQHEKKKLQKIYNLTEMLRDRIGDV 282 ++ + + + ++L + + Sbjct: 299 SKSSDLQKIVMNNINRCTKKDKILNNTLKKC 329
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 101 bits (253), Expect = 5e-28 Identities = 73/261 (27%), Positives = 122/261 (46%), Gaps = 25/261 (9%) Query: 4 KVVIITGGSSGMGKGMATRFAKEGARVVITGRTKEKLEEAKLEI-------EQFPGQILT 56 K+ ITG + G+G+ +A A +GA + EKLE+ + E FP Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP----- 63 Query: 57 VQMDVRNTDDIQKMIEQIDEKFGRIDILINNAAGNFICPAEDLSVNGWNSVINIVLNGTF 116 DVR++ I ++ +I+ + G IDIL+N A LS W + ++ G F Sbjct: 64 --ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 117 YCSQAIGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGVLAMTKTLAVEWGRKYG 176 S+++ KY +++ G+I+ + + A + A++KA + TK L +E +Y Sbjct: 122 NASRSVSKYMMDRR-SGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA-EYN 179 Query: 177 IRVNAIAPGPIERTGGADKLWISEEMAKRTIQ--------SVPLGRLGTPEEIAGLAYYL 228 IR N ++PG T LW E A++ I+ +PL +L P +IA +L Sbjct: 180 IRCNIVSPGST-ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFL 238 Query: 229 CSDEAAYINGTCMTMDGGQHL 249 S +A +I + +DGG L Sbjct: 239 VSGQAGHITMHNLCVDGGATL 259
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 26.2 bits (58), Expect = 0.022 Identities = 6/39 (15%), Positives = 8/39 (20%) Query: 40 FFPFFGVPFLAGIAGGLLGGALAFGPRPYYPPYPPPFPP 78 P + L + F P P P Sbjct: 29 TAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVPVFS 67
>cloacin#Cloacin signature. Length = 551 Score = 27.4 bits (60), Expect = 0.047 Identities = 16/109 (14%), Positives = 33/109 (30%) Query: 33 AFENAAKQEKTMFEDAKKLETLEKEGQELYNQIVQEGKDNNQTVKEKLNQAVKNTDEREK 92 + A K + K+ + +++ Q Q + +N D K Sbjct: 357 ELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAK 416 Query: 93 VLKKEKESLNKAQEEVKSADKYVKKIEDKKLKDQADKVKSTYEKRHDSF 141 +L+ A E K + + E+ ++ K + HD Sbjct: 417 EKSDADAALSSAMESRKKKEDKKRSAENNLNDEKNKPRKGFKDYGHDYH 465
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 41.9 bits (98), Expect = 2e-07 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Query: 1 MKQKGFTLLEMLLVLFAISVLSMVTYFNVHSLYEKQKIEQFLRQFSNDILYMQQLAINRQ 60 M+Q+GFTLLEM+L+L + V + + + + + R F + ++QQ + Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLAR-FEAQLRFVQQRGLQTG 59 Query: 61 KHYTLRWHKDRHMYY 75 + + + H DR + Sbjct: 60 QFFGVSVHPDRWQFL 74
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 50.3 bits (120), Expect = 2e-11 Identities = 18/65 (27%), Positives = 41/65 (63%) Query: 1 MQNEEGFTLLEMLLVMVVITVLLLLIIPDVVTQRSSVEGKGCKAYVKSIEAQVQVYQLQH 60 + GFTLLE+++V+V+I VL L++P+++ + + + + + ++E + +Y+L + Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDN 63 Query: 61 NKIPT 65 + PT Sbjct: 64 HHYPT 68
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 91.4 bits (227), Expect = 9e-23 Identities = 61/350 (17%), Positives = 150/350 (42%), Gaps = 22/350 (6%) Query: 7 SLSDQVILLKRLGELLEKGYSLLQALEFLRFQLPLEKKVQLQRMIDGLKD----GKSLHD 62 S SD +L ++L L+ L +AL+ + Q +K L +++ ++ G SL D Sbjct: 66 STSDLALLTRQLATLVAASMPLEEALDAVAKQS---EKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 63 SFHQLKFHQEMLSYLFYA-----EQHGDISFALQQGSALLYKKDKYRKDMIKIMQYPMFL 117 + +K L+ A E G + L + + ++ + R + + M YP L Sbjct: 123 A---MKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVL 179 Query: 118 AIFLIIMILIFNRILLPQVDMVYSSFGSTAPLFTEQILSTIKLL----PYLIISTLFIIM 173 + I ++ I +++P+V + PL T ++ + P+++++ ++ Sbjct: 180 TVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLA---LLA 236 Query: 174 IVFGVYIVYFRKLPHMKQVKIILRIPLVKTFLILKHSHYFATQLSGLLHGGLSVLEALTI 233 ++ ++ + + +L +PL+ ++ +A LS L + +L+A+ I Sbjct: 237 GFMAFRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRI 296 Query: 234 MMEQKYHPFFQYEAGRIERQLIAGEPLQSIIAKSEYYEEELSYIITHGQANGNLAIELGD 293 + + + ++ + G L + ++ + + ++I G+ +G L L Sbjct: 297 SGDVMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLER 356 Query: 294 YSDLIMEKMERKIKRMLVIIQPILFTCIGGIVVLMYLAMIMPMFQMMNSI 343 +D + ++ L + +P+L + +V+ + LA++ P+ Q+ + Sbjct: 357 AADNQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 26.9 bits (59), Expect = 0.033 Identities = 16/68 (23%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 39 IEKNMELFIELIRD-KENPFETGYSSSISIAVLDEEGKMIEFYTVPIWECCSYFL-GVPL 96 IE + F L + KE+ F TGY+ + ++ DE +++ + + + F G Sbjct: 157 IETEYKWFYSLQFNIKESAFTTGYAIASWLSEQDESKRVVASFGGGAFPGVTTFNEGFAK 216 Query: 97 QIRFWGSK 104 I ++ K Sbjct: 217 GILYYNQK 224
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.2 bits (73), Expect = 0.001 Identities = 16/86 (18%), Positives = 29/86 (33%), Gaps = 13/86 (15%) Query: 41 GTLVGYMHENKLIAAGGVFPFKDRFSTIGMLIVHPNFQGQGIGRTLLNHCLEHTHPK--- 97 Y EN I + + ++ I + V +++ +G+G LL+ +E Sbjct: 65 KAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFC 124 Query: 98 ------QPIALIATKAGEPLYTSCGF 117 Q I + A Y F Sbjct: 125 GLMLETQDINISACHF----YAKHHF 146
>PF06917#Periplasmic pectate lyase Length = 555 Score = 27.6 bits (61), Expect = 0.034 Identities = 7/31 (22%), Positives = 19/31 (61%) Query: 71 EELGEDIYEQDEPRGYFGAAEIYKYAKLHNT 101 ++G+D++++ RG F + ++Y ++ N Sbjct: 470 WQIGDDLFKRHYHRGLFVESAQHRYFRIDNP 500
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.3 bits (60), Expect = 0.014 Identities = 14/39 (35%), Positives = 18/39 (46%) Query: 48 WSGVFMFCTINLLNKWLGIETSNTSPYLPTSVATILKEN 86 +S F TI L + LG + +SP L V L EN Sbjct: 791 YSVNTTFVTIADLVQALGADPGKSSPMLEGQVRDWLNEN 829
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 170 bits (431), Expect = 6e-49 Identities = 74/203 (36%), Positives = 102/203 (50%), Gaps = 19/203 (9%) Query: 173 GGPTIGAPEAWNLKDPSGKSLDGKGMKVAIIDSGVDYTHPDLKANYIGGYDTVDEDA--- 229 G I AP W G+G+KVA++D+G D HPDLKA IGG + D+D Sbjct: 25 GVEMIQAPAVW-------NQTRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDP 77 Query: 230 -DPMDGNVHGTHVAGIIAGNG---KIKGVAPNASILAYRVMNDGGTGTTDDIIQGIERAI 285 D N HGTHVAG IA + GVAP A +L +V+N G+G D IIQGI AI Sbjct: 78 EIFKDYNGHGTHVAGTIAATENENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAI 137 Query: 286 QDGADVLNLSLGQDLNVPDQPVTLTLERAAKLGITAVVSNGNDGPKPWSVDA---PGNAS 342 + D++++SLG +VP + +++A I + + GN+G D PG + Sbjct: 138 EQKVDIISMSLGGPEDVP--ELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYN 195 Query: 343 SVISVGASTVSIPFPTFQVAGSS 365 VISVGA F + + Sbjct: 196 EVISVGAINFDRHASEFSNSNNE 218 Score = 84.9 bits (210), Expect = 8e-20 Identities = 42/129 (32%), Positives = 59/129 (45%), Gaps = 19/129 (14%) Query: 492 FSSRGPSQGSWLIKPDIVAPGVQITSTVPRGGYESHNGTSMAAPQVAGAVALLRQ----- 546 FS+ D+VAPG I STVP G Y + +GTSMA P VAGA+AL++Q Sbjct: 212 FSNSNNE-------VDLVAPGEDILSTVPGGKYATFSGTSMATPHVAGALALIKQLANAS 264 Query: 547 MHPDWTTQQLKASLANTAKTLKDVNENTYPIMTQGSGLINIPKAAQTDVLVKPNNVSFGL 606 D T +L A L L + + +G+GL+ A + + G+ Sbjct: 265 FERDLTEPELYAQLIKRTIPLGNSPKM------EGNGLLY-LTAVEELSRIFDTQRVAGI 317 Query: 607 IKPNSGKVK 615 + S KVK Sbjct: 318 LSTASLKVK 326
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.0 bits (226), Expect = 3e-23 Identities = 35/152 (23%), Positives = 74/152 (48%), Gaps = 7/152 (4%) Query: 7 RILLIEDEVSIAELQRDYLEINDFQVDVEHSGETGLQMALQEDYDLIILDIMLPKMNGFE 66 IL+ +D+ +I + L + V + + T + D DL++ D+++P N F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 67 ICKQIRAI-KDIPILLVSAKKEDIDKIRGLGLGADDYITKPFSPSELVARVKAHISRYER 125 + +I+ D+P+L++SA+ + I+ GA DY+ KPF +EL+ + ++ +R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 126 LLGNVSKQ-RDTLYIHGIS-----IDQRARKV 151 + +D + + G S I + ++ Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARL 156
>PF06580#Sensor histidine kinase Length = 349 Score = 33.7 bits (77), Expect = 0.001 Identities = 18/101 (17%), Positives = 37/101 (36%), Gaps = 24/101 (23%) Query: 379 LIHNSVKY---MDKEEKKITVTVSSDNNKVIVKVMDNGSGIESDTLPYIFERFYRAEQSR 435 L+ N +K+ + KI + + DN V ++V + GS +T Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT--------------- 307 Query: 436 NSSTGGSGLGLAIAKQIIEEHGGN---IWAESELGEGTSIF 473 +G GL ++ ++ G I + G+ ++ Sbjct: 308 ---KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.4 bits (66), Expect = 0.011 Identities = 16/96 (16%), Positives = 33/96 (34%), Gaps = 14/96 (14%) Query: 130 GGTALIPASEHGYVDVIKELLTRTNIDVNHVNNLGWTALMEAIVLSNGNETQQQVIRLLI 189 G T L+ + V+ + L+R DV +N L I L++ Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNA--ATLWRWI--------AAGDGDLVV 52 Query: 190 EHGADINIPDNDGVTPLEHARAHHFEEIEKILLEGH 225 D+ +PD + L + ++ +++ Sbjct: 53 ---TDVVMPDENAFDLLPRIKKAR-PDLPVLVMSAQ 84
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 145 bits (368), Expect = 2e-48 Identities = 76/134 (56%), Positives = 96/134 (71%), Gaps = 9/134 (6%) Query: 1 MWNEFKKFAFKGNVIDLAVGVVIGAAFGKIVSSLVKDIITPLLGMVLGGVDFTDLKITFG 60 + EF++FA +GNV+DLAVGV+IGAAFGKIVSSLV DII P LG+++GG+DF +T Sbjct: 3 IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62 Query: 61 KS-------SIMYGNFIQTIFDFLIIAAAIFMFVKVFNKLTSKREEEKEEEIPEPTKEEE 113 + + YG FIQ +FDFLI+A AIFM +K+ NKL K+EE P PTKEE Sbjct: 63 DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAA--PAPTKEEV 120 Query: 114 LLGEIRDLLKQQNS 127 LL EIRDLLK+QN+ Sbjct: 121 LLTEIRDLLKEQNN 134
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 31.7 bits (72), Expect = 0.002 Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 4/71 (5%) Query: 1 MKIGIIGAAGKAGSRILKEALDRGHEVTAI-VRNT---AKITEENVKVLEKDVFALTSND 56 MK + GAAG G + K L+ GH+V I N + + +++L + F D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 57 LQAFDVVVNAF 67 L + + + F Sbjct: 61 LADREGMTDLF 71
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 62.9 bits (153), Expect = 5e-13 Identities = 77/342 (22%), Positives = 136/342 (39%), Gaps = 32/342 (9%) Query: 11 VQTNRRSMFALLALAISAFGIGTTEFISVGLLPSISKDLNVSVTTA---GLTVSLYALGA 67 ++ NR + L +A+ A GIG + + +LP + +DL S G+ ++LYAL Sbjct: 1 MKPNRPLIVILSTVALDAVGIG----LIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQ 56 Query: 68 AVGAPVLTALTASMSRKTLLMWIMVIFIIGNGIAAVATSFTILIIARIVSAFAHGVFMSI 127 APVL AL+ R+ +L+ + + I A A +L I RIV+ Sbjct: 57 FACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA 116 Query: 128 GSTIAAAIVPENKRASAIAIMFTGLTVATITGVPIGTFIGQQFGWRASFMAIVVIGIIAF 187 G+ I A I ++RA M + G +G +G F A F A + + F Sbjct: 117 GAYI-ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG-GFSPHAPFFAAAALNGLNF 174 Query: 188 IANSILVPSNLK------NGVPVSFRDQFKLIKNGR-----LLLVFIITALGYGGT--FV 234 + L+P + K ++ F+ + + + FI+ +G +V Sbjct: 175 LTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWV 234 Query: 235 TFTYLSPLLQEVTGFEASTVTIILLVYGIAIAIGN-MVGGKLSNH-NPIRALFYMFLIQA 292 F ++ ++A+T+ I L +GI ++ M+ G ++ RAL + Sbjct: 235 IFG------EDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADG 288 Query: 293 IILFVLTFTAPFKVAGLITIIFMGLFAFMNVPGLQVYVVILA 334 +L F +A I ++ M P LQ + Sbjct: 289 TGYILLAFATRGWMAFPIMVLLASGGIGM--PALQAMLSRQV 328
>PF07472#Fucose-binding lectin II Length = 245 Score = 27.7 bits (61), Expect = 0.017 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 8/66 (12%) Query: 15 VQISASQGQLDVLDQLLKPEVQESLTTLVEQLPKLTELVNILTKSYDFAQTVATDEVLKS 74 VQ + Q LD + Q + T LVE+LP+ V+I T Y F ++V K+ Sbjct: 24 VQANGDQAVLDRMRQFMT-------TQLVEKLPQYDVFVDIATIPYSFDVGSWQNKV-KA 75 Query: 75 DTVGAI 80 D G + Sbjct: 76 DAAGQV 81
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 29.6 bits (66), Expect = 0.028 Identities = 23/92 (25%), Positives = 36/92 (39%), Gaps = 18/92 (19%) Query: 333 DEIEQGFKEMPTFQSSKETKNIVEWLVDLGIEPSRRQAREDINNGAISMN---------- 382 D I+ KEMP + KE K + + S E+IN+ S+N Sbjct: 77 DMIKLAPKEMPLESAEKEEKKSED------NKKSEEDHTEEINDKIYSLNYNELEVLAKN 130 Query: 383 GEKVTDVGTDVTVENSFDGRFIIIRKGKKNYS 414 GE + + +FI+I + KKN + Sbjct: 131 GETIENF--VPKEGVKKADKFIVIERKKKNIN 160
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 63.1 bits (153), Expect = 5e-14 Identities = 21/62 (33%), Positives = 38/62 (61%) Query: 2 KEKERLIIEMAMKLFATKGVNATSVQEIVTACGISKGAFYLYFKSKEELLLATLRYYYDK 61 +E + I+++A++LF+ +GV++TS+ EI A G+++GA Y +FK K +L Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 62 IQ 63 I Sbjct: 70 IG 71
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 669 bits (1728), Expect = 0.0 Identities = 240/1066 (22%), Positives = 459/1066 (43%), Gaps = 68/1066 (6%) Query: 4 IINFSLKNKFAVWLLTIIVTIAGIYSGLNMKLETIPDITTPVVTVTTVYPGATPEEVADK 63 + NF ++ W+L II+ +AG + L + + P I P V+V+ YPGA + V D Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 64 VSKPMEEQLQNLSGVNVVSSSSFQNASS-IQVEYDFDKNMEKAETEIKDALANVK--LPE 120 V++ +E+ + + + +SS+S S I + + + + A+ ++++ L LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 GVKDPKVSRVNF--NAFPVISLSVASKNESLATLTENVEKNVVPGLKGLDGVASVQISGQ 178 V+ +S + V + + +++ V NV L L+GV VQ+ G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 179 QVDEVQLVFKKDKMKELGLSEDTVKNVIKGSDVSLPLGLYTFKDT------EKSVVVDGN 232 Q +++ D + + L+ V N +K + + G S++ Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 233 ITTMKALKELKIPAVPSSASSQGSQTAGAGAQMPQMNPAAMNGIPTVTLSEIADIKEVGK 292 + ++ + +G V L ++A ++ G+ Sbjct: 240 FKNPEEFGKVTLRVNS-------------------------DGSV-VRLKDVARVELGGE 273 Query: 293 A-ESISRTNGKEAIGIQIVKAADANTVDVVNAVKDKVKELEKKY-KDLEIISTFDQGAPI 350 I+R NGK A G+ I A AN +D A+K K+ EL+ + + ++++ +D + Sbjct: 274 NYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFV 333 Query: 351 EKSVETMLSKAIFGAIFAIVIIMLFLRNIRTTLISVVSIPLSLLIAVLVIKQMDITLNIM 410 + S+ ++ + +++ LFL+N+R TLI +++P+ LL ++ ++N + Sbjct: 334 QLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTL 393 Query: 411 TLGAMTVAIGRVVDDSIVVIENIYRRMSLSEEKLRGKDLIREATKEMFIPIMSSTIVTIA 470 T+ M +AIG +VDD+IVV+EN+ R M E+KL K+ ++ ++ ++ +V A Sbjct: 394 TMFGMVLAIGLLVDDAIVVVENVERVM--MEDKLPPKEATEKSMSQIQGALVGIAMVLSA 451 Query: 471 VFLPLGLVKGMIGEMFLPFALTIVFALLASLLVAVTIVPMLAHSLFKKESMREKEVHH-- 528 VF+P+ G G ++ F++TIV A+ S+LVA+ + P L +L K S E Sbjct: 452 VFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGF 511 Query: 529 ----EEKPSKLANIYKRILAWALNHKIITSSIAVLLLVGSLALVPIIGVSFLPSEEEKMI 584 N Y + L I L++ G + L + SFLP E++ + Sbjct: 512 FGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVF 571 Query: 585 IATYNPEPGQTLEDVEKIATKAEKHFQDNKDVKTIQ--FSLGGENPMSPGQSNQAMFFVQ 642 + G T E +K+ + ++ + ++ F++ G + Q N M FV Sbjct: 572 LTMIQLPAGATQERTQKVLDQVTDYYL-KNEKANVESVFTVNGFSFSGQAQ-NAGMAFVS 629 Query: 643 YD--NDTKNFEKEKEQVVKDLQKMSGKGEWKN---------QDFGASGGSNEIKLYVYGD 691 + E E V+ + GK + G + G + + G Sbjct: 630 LKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGL 689 Query: 692 SSEDIKPVVKDIQNIMKKN-KDLKDIDSSIAKTYAEYTLVADQEKLSKMGLTAAQIGMGL 750 + + + + ++ L + + + A++ L DQEK +G++ + I + Sbjct: 690 GHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTI 749 Query: 751 SNQHDRPVLTTIKKDGKDVNVYVEAEKQTYETIDDLTNRKITTPLGNEVAVKDVMTVKEG 810 S + G+ +YV+A+ + +D+ + + G V T Sbjct: 750 STALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWV 809 Query: 811 ETSNTVKHRDGRVYAEVSAKLTSDDVSK-ASAAVQKEVDKMDLPSGVDVSMGGVTKDIEE 869 S ++ +G E+ + S A A ++ K LP+G+ G++ Sbjct: 810 YGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERL 867 Query: 870 SFKQLGLAMLAAIAIVYFVLVVTFGGALAPFAILFSLPFTIIGALVALLISGETLSVSAM 929 S Q + + +V+ L + P +++ +P I+G L+A + + V M Sbjct: 868 SGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFM 927 Query: 930 IGALMLIGIVVTNAIVLIDRVIH-KENEGLSTREALLEAGATRLRPILMTAIATIGALIP 988 +G L IG+ NAI++++ E EG EA L A RLRPILMT++A I ++P Sbjct: 928 VGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLP 987 Query: 989 LALGFEGSGLISKGLGVTVIGGLTSSTLLTLLIVPIVYEVLSKFKK 1034 LA+ +G+ V+GG+ S+TLL + VP+ + V+ + K Sbjct: 988 LAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCFK 1033 Score = 93.4 bits (232), Expect = 2e-21 Identities = 93/518 (17%), Positives = 198/518 (38%), Gaps = 46/518 (8%) Query: 546 ALNHKIITSSIAVLLLVGSLALVPIIGVSFLPSEEEKM--IIATYNPEPGQTLEDVE-KI 602 + I +A++L++ + + V+ P+ + A Y PG + V+ + Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANY---PGADAQTVQDTV 61 Query: 603 ATKAEKHFQDNKDVKTIQFSLGGENPMSPGQSNQAMFFVQYDNDTKNFEKEKEQVVKDLQ 662 E++ ++ + S S ++ + + + QV LQ Sbjct: 62 TQVIEQNMNGIDNLMYMS---------STSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQ 112 Query: 663 KMSGK--GEWKNQDFGASGGSNEIKLYVYGDSSEDIKPVVKDIQNIMKKN--KDLKDID- 717 + E + Q S+ L V G S++ DI + + N L ++ Sbjct: 113 LATPLLPQEVQQQGISVEKSSSSY-LMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNG 171 Query: 718 ----SSIAKTYAEYTLVADQEKLSKMGLTAAQIGMGLSNQHDR----PVLTTIKKDGKDV 769 YA + D + L+K LT + L Q+D+ + T G+ + Sbjct: 172 VGDVQLFGAQYA-MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQL 230 Query: 770 NVYVEAEKQTYETIDDLTNRKI-TTPLGNEVAVKDVMTVKEG--ETSNTVKHRDGRVYAE 826 N + A+ + ++ + G+ V +KDV V+ G + + Sbjct: 231 NASIIAQTRFK-NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGL 289 Query: 827 VSAKLTSDDVSKASAAVQKEVDKM--DLPSGVDVSMGGVTKD----IEESFKQLGLAMLA 880 T + + A++ ++ ++ P G+ V D ++ S ++ + Sbjct: 290 GIKLATGANALDTAKAIKAKLAELQPFFPQGMKVL---YPYDTTPFVQLSIHEVVKTLFE 346 Query: 881 AIAIVYFVLVVTFGGALAPFAILFSLPFTIIGALVALLISGETLSVSAMIGALMLIGIVV 940 AI +V+ V+ + A ++P ++G L G +++ M G ++ IG++V Sbjct: 347 AIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLV 406 Query: 941 TNAIVLIDRVI-HKENEGLSTREALLEAGATRLRPILMTAIATIGALIPLALGFEGS-GL 998 +AIV+++ V + L +EA ++ + ++ A+ IP+A F GS G Sbjct: 407 DDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAF-FGGSTGA 465 Query: 999 ISKGLGVTVIGGLTSSTLLTLLIVPIVYEVLSKFKKKK 1036 I + +T++ + S L+ L++ P + L K + Sbjct: 466 IYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAE 503
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 3e-14 Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 6/126 (4%) Query: 3 KVLVVDDEMLARDELKYLLERTK-EVEIIGEADCVEDALEELMKNKPDIVFLDIQLSDDN 61 +LV DD+ R L L R +V I A + D+V D+ + D+N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNA---ATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GFEIANILKKMKNPPAIVFATAYDQY--ALQAFEVDALDYILKPFDEERIVQTLKKYKKQ 119 F++ +KK + ++ +A + + A++A E A DY+ KPFD ++ + + + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 120 KQSQIE 125 + + Sbjct: 122 PKRRPS 127
>PF06580#Sensor histidine kinase Length = 349 Score = 229 bits (586), Expect = 3e-72 Identities = 65/216 (30%), Positives = 111/216 (51%), Gaps = 13/216 (6%) Query: 359 QLELGEAELQSKLLQDAEIKALQAQINPHFLFNAINTVSALCRTDVEKARKLLLQLSVYF 418 Q E+ + ++ + Q+A++ AL+AQINPHF+FNA+N + AL D KAR++L LS Sbjct: 146 QAEIDQWKMA-SMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELM 204 Query: 419 RCNLQGARQLLIPLEQELNHVQAYLSLEQARFPNKYEVKMYIEDELKTTLVPPFVLQLLV 478 R +L+ + + L EL V +YL L +F ++ + + I + VPP ++Q LV Sbjct: 205 RYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLV 264 Query: 479 ENALRHAFPKKQPVCEVEVHVFEKEGMVHFEVKDNGQGIEEERLEQLGKMVVSSKKGTGT 538 EN ++H + ++ + + G V EV++ G + +K+ TGT Sbjct: 265 ENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN-----------TKESTGT 313 Query: 539 ALYNINERLIGLFGKETMLHIESEVNEGTEITFVIP 574 L N+ ERL L+G E + + + + +IP Sbjct: 314 GLQNVRERLQMLYGTEAQIKLSEKQGKVNA-MVLIP 348
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 54.1 bits (130), Expect = 5e-10 Identities = 81/411 (19%), Positives = 148/411 (36%), Gaps = 28/411 (6%) Query: 34 LDMLLLSFVLVYILKEFHLSPVEGGNLTLATTIGMLIGSYLFGFIADLFGRIRTMAFTIL 93 L+ ++L+ L I +F+ P + A + IG+ ++G ++D G R + F I+ Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 94 LFSLATALIYFATDYWQLLIL-RFLVGMGVGGEFGIGMAIVTETWSKEMRAKATSVVALG 152 + + + + ++ LLI+ RF+ G G + M +V KE R KA ++ Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 153 WQFGVLIASLLPAFIVPHFGWRAVFLFGLIPALLAVYVRKSLSEPKIWEQKQRYKKELLQ 212 G + + I + W + L +I + ++ K L + + K +L Sbjct: 148 VAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILM 207 Query: 213 KEAEGN--LTTTEAA-----------------QLKQMKKFPLRKLFANKKVTITTIGLII 253 L TT + K F L N I ++ Sbjct: 208 SVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMI----GVL 263 Query: 254 MSFIQNFGYYGIFTWMPTILANKYNYTLAKA-SGWMFISTIGMLIGIATFGILADKIGRR 312 I G + +P ++ + + + A+ S +F T+ ++I GIL D+ G Sbjct: 264 CGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPL 323 Query: 313 KTFTIYYVGGTIYCLIY-FFLFTDSTLLLWG-SALLGFFANGMMGGFGAVLAENYPAEAR 370 I ++ L F L T S + +LG + V + EA Sbjct: 324 YVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAG 383 Query: 371 STAENFIFGTGRGLAGFGPVIIGLLAAGGNLMGALSLIFIIYPIGLVTMLL 421 + F + G G I+G L + L L + + L + LL Sbjct: 384 AGMSLLNFTSFLS-EGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLL 433
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 35.9 bits (83), Expect = 1e-04 Identities = 12/26 (46%), Positives = 15/26 (57%) Query: 3 KVLVLGGTRFFGKHLVEALLKDGHDV 28 K LV G F G H+ + LL+ GH V Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQV 27
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 58.1 bits (140), Expect = 2e-11 Identities = 34/179 (18%), Positives = 64/179 (35%), Gaps = 40/179 (22%) Query: 95 SEADSEAGTGSG-VIYKKTNDQAYIVTNNHVVAGANRIEVSLS------------DGKKV 141 EA + SG V+ K T ++TN HVV + +L +G Sbjct: 95 VEAPTGTFIASGVVVGKDT-----LLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFT 149 Query: 142 PGKVLGTDVVTDLAVLEIDA----KHVKKVIE---IGDSNAVRRGEPVIAIGNPLGLQFS 194 ++ DLA+++ KH+ +V++ + ++ + + + G P + Sbjct: 150 AEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVA 209 Query: 195 GTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGALVNAAGQLIGINS 253 T + E +Q D + GNSG + N ++IGI+ Sbjct: 210 ---TMWESKGKITYLKG------------EAMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>PF06580#Sensor histidine kinase Length = 349 Score = 37.5 bits (87), Expect = 1e-04 Identities = 17/104 (16%), Positives = 35/104 (33%), Gaps = 25/104 (24%) Query: 502 VLYNIISNALKY----SPEGGTVTYRLRDRGELLEISVSDQGMGIPKENVDKIFERFYRV 557 ++ ++ N +K+ P+GG + + + + V + G K Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------ 306 Query: 558 DKARSRQMGGTGLGLAIAKEMIEAHGG---SIWAKSEEGKGTTI 598 TG GL +E ++ G I ++GK + Sbjct: 307 ------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.9 bits (236), Expect = 1e-24 Identities = 31/140 (22%), Positives = 69/140 (49%), Gaps = 4/140 (2%) Query: 1 MMGKKILVVDDEKPIADILKFNLEKEGFEIVMAHDGDEAIEKATEEQPDMVLLDIMLPGK 60 M G ILV DD+ I +L L + G+++ + + D+V+ D+++P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLEVCREIRK-SSEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFS---TRELLARVKA 116 + ++ I+K ++P+++++A+++ + + E GA DY+ KPF ++ R A Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 117 NLRRHQQGGAAEKEENTEMV 136 +R + ++ +V Sbjct: 121 EPKRRPSKLEDDSQDGMPLV 140
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 28.3 bits (63), Expect = 0.040 Identities = 9/48 (18%), Positives = 20/48 (41%), Gaps = 7/48 (14%) Query: 152 DREAFKEKLEQNLAQKNRLFEK-------MYDTEGFSVDEIFEEYFEY 192 ++ + L L+ L+ K + F++ E FEE +++ Sbjct: 9 NQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDH 56