>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 33.6 bits (76), Expect = 0.002 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 9/74 (12%) Query: 192 HAHHHHVLHADLKPENILID-PNKRPKLLDFNLTQKVQSNGGESPPALIAFSQNFASPEQ 250 H V+H D+KP N++ D + P ++D L S GE P F+++F +PE Sbjct: 260 HLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGL----HSRSGEQPK---GFTESFKAPEL 312 Query: 251 QTGQF-LTAQSDVY 263 G + +SDV+ Sbjct: 313 GVGNLGASEKSDVF 326
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 28.3 bits (63), Expect = 0.047 Identities = 15/76 (19%), Positives = 26/76 (34%), Gaps = 10/76 (13%) Query: 3 LLWILCLAFGGLSASCVFVIMLHVTL------LI---NHIFMAQQNKKTRTTLQDVADQV 53 L W++ G L+ + V + L +I + A K D+ Sbjct: 34 LAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAKLHGDATITYDEA 93 Query: 54 GVTKMTVSRYMRNPES 69 V K ++ Y+R E Sbjct: 94 -VRKYFLATYVRYREG 108
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 210 bits (537), Expect = 5e-73 Identities = 72/157 (45%), Positives = 107/157 (68%) Query: 8 MKVIYPGTFDPVTNGHLNLIERTHEMFDEVVIGVAASPSKNTMFTLEERVALMEEVVAHL 67 M IYPG+FDP+T GHL++IER +FD+V + V +P+K MF+++ER+ + + +AHL Sbjct: 1 MNAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHL 60 Query: 68 PGVTVKGFSGLLVDFARQEQAKVLIRGLRTTVDFEYEFGLTNMYRKLLPGIESVFLTPEE 127 P V F GL V++ARQ QA ++RGLR DFE E + N + L +E+VFLT Sbjct: 61 PNAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTST 120 Query: 128 EFAFLSSTIVREVAIHGGSIEQFVPAAVANAIEKKVN 164 E++FLSS++V+EVA GG++E FVP+ VA A+ + + Sbjct: 121 EYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFH 157
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 45.5 bits (108), Expect = 2e-07 Identities = 41/214 (19%), Positives = 77/214 (35%), Gaps = 26/214 (12%) Query: 34 RFLVLGGAGSIGQAVTKEIFKRNPKKLHVVDISENNMVELVRDIRSSFGYIDGDFQTFAL 93 ++LV G AG IG V+K + + + + + ++++ V L + FQ + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLA--QPGFQFHKI 59 Query: 94 DIGSLEYDAFIKADGKFDYVLNLSALKHVR-SEKDPYTLMRMIDVNVFNTDKTIQQSIDA 152 D+ E + A G F+ V VR S ++P+ D N+ ++ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAY---ADSNLTGFLNILEGCRHN 116 Query: 153 GAKKYFCVST---------------DKAANPVNMMGASKRIMEMFLMRKSEQIAISTA-- 195 + S+ D +PV++ A+K+ E+ S + Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 196 RFANVAFSDGS---LLHGFNQRIQKRQPIVAPND 226 RF V G L F + + + + I N Sbjct: 177 RFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNY 210
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 30.1 bits (67), Expect = 0.013 Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 14/80 (17%) Query: 48 VSSVGKFVDDFERKIE---------VYTGTAKAVATVNGTAALHAALYMADVQRGDLVIT 98 + ++ K +D K+E V + A V G+ +L M+DV +G +V + Sbjct: 60 LDTINKVTEDVSSKLEGVRESSLELVESNDAGVVKKFVGSMSL-----MSDVAKGTVVAS 114 Query: 99 QALTFVATCNALYHMGAEPI 118 Q T VA C+ + GA + Sbjct: 115 QEATIVAKCSGMVAEGANKV 134
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 61.6 bits (149), Expect = 2e-13 Identities = 56/270 (20%), Positives = 103/270 (38%), Gaps = 34/270 (12%) Query: 2 LKDKKIVIAGAGGLLGASVVKSILEAGGSVVATDVSLEHLKARLSSVGVNLADTHLTMHE 61 ++ K I GA +G +V +++ G + A D + E L+ +SS+ H Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSL--KAEARHAEAFP 63 Query: 62 LDITRSDAL----TRFWQEAEGVTGAVNCTYPRTKSYGAKFFDVTLDSFNENVSIHLGSA 117 D+ S A+ R +E + VN ++ + + S++ Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVA---GVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 118 FLFSQQCAAYFVNKEQPFSLVNISSIYGVIAPKFSVYDNTPMTMPVEYAAIKSAIVHLNK 177 F S+ + Y +++ S+V + S P T YA+ K+A V K Sbjct: 121 FNASRSVSKYMMDRRSG-SIVTVGSNPA----------GVPRTSMAAYASSKAAAVMFTK 169 Query: 178 YVVSYINDSRFRVNSVSPGGI-LDGQPEAFLDAYRKNTHGAGMLNV-------------E 223 + + + R N VSPG D Q + D G L Sbjct: 170 CLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPS 229 Query: 224 EMTGSIVYLLSDQSKYVTGQNIIVDDGFSL 253 ++ ++++L+S Q+ ++T N+ VD G +L Sbjct: 230 DIADAVLFLVSGQAGHITMHNLCVDGGATL 259
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 86.8 bits (215), Expect = 1e-21 Identities = 77/358 (21%), Positives = 130/358 (36%), Gaps = 88/358 (24%) Query: 2 IIVTGGAGMIGSNIVKALNEAGINDILVVDNLKN--------------GKKFKNLVDLDI 47 +VTG AG IG ++ K L EAG + ++ +DNL + + +D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 48 TDYMDRDDFLTQIMAGDDFGPIEAIFHEGACSATTEWDGKYMMLNNYEYSK-------EL 100 D + +T + A F E +F A +Y + N + Y+ + Sbjct: 62 ADR----EGMTDLFASGHF---ERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNI 109 Query: 101 LHYCLDREIP-FLYASSAATYGETET--FVEEREYEGALNVYGYSKQQFDNYVRRLWKDA 157 L C +I LYASS++ YG F + + +++Y +K K Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATK-----------KAN 158 Query: 158 EEHGEQLSQI-----TGFRYFNVYGPREDHKGSMASVAFHLNNQINAGENPKLFEGSGHF 212 E S + TG R+F VYGP + MA F + G++ ++ G Sbjct: 159 ELMAHTYSHLYGLPATGLRFFTVYGPWG--RPDMA--LFKFTKAMLEGKSIDVY-NYGKM 213 Query: 213 KRDFVYVGDVCKVNL------------WFLENGVSG-------IFNCGTGRAESFEEVAK 253 KRDF Y+ D+ + + W +E G ++N G + + Sbjct: 214 KRDFTYIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQ 273 Query: 254 AVVKHHN-KGEIQTIPFPDHLKGAYQEFTQADLTKLRAAGCDVEFK---TVAEGVAEY 307 A+ + + +P T AD L + F TV +GV + Sbjct: 274 ALEDALGIEAKKNMLPLQP----GDVLETSADTKALYE---VIGFTPETTVKDGVKNF 324
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 24.8 bits (54), Expect = 0.033 Identities = 12/50 (24%), Positives = 22/50 (44%) Query: 6 LAILMALSASTAFAAEEAGSAGAASASATGTTAVAVGAAAAVTVVAVAAS 55 L++L+ S + AFA E A + G +T V ++ + + S Sbjct: 9 LSVLLLCSTANAFADEFADNLGLTLLPVEPSTQVNAASSHTKPPLVIFLS 58
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 44.9 bits (106), Expect = 5e-08 Identities = 45/187 (24%), Positives = 71/187 (37%), Gaps = 26/187 (13%) Query: 26 ALSAISLGLCSFTASA----DFYAGALVSYSNAEYHHS---STSSVTEGNPFLLQAQAGY 78 A++ G + +A +Y GA + + ++YH + + + T N A GY Sbjct: 7 AIAVALAGFATVAQAAPKDNTWYTGAKLGW--SQYHDTGFINNNGPTHENQLGAGAFGGY 64 Query: 79 FFNDYVALEARY---GTSVQRESGLAIDSLASGF---VKLNMPVSERFAFYGLAGYSSVQ 132 N YV E Y G + S A G KL P+++ Y G + Sbjct: 65 QVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMVWR 124 Query: 133 IDQQN--VGSNKDQGFS--FGLGMHYALDKHNAVVFEFVD-------NTSEDQVRLNALT 181 D ++ G N D G S F G+ YA+ A E+ +T + L+ Sbjct: 125 ADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLS 184 Query: 182 LGFQHRF 188 LG +RF Sbjct: 185 LGVSYRF 191
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 178 bits (454), Expect = 2e-55 Identities = 78/358 (21%), Positives = 146/358 (40%), Gaps = 48/358 (13%) Query: 1 MKILVTGGAGFIGSALVRHIIKNTSDSVVNVDCLT--YAGNL-ESLGSVIQSERYVFEQV 57 MK LVTG AGFIG + + +++ VV +D L Y +L ++ ++ + F ++ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 NICDRAELNRVFEAHKPDAVMHLAAESHVDRSITGPAAFIETNVVGTYTMLEATREYWSK 117 ++ DR + +F + + V V S+ P A+ ++N+ G +LE R + Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 118 LDDNAKAAFRFHHISTDEVYGDLPHPDEVSDGKELPMFLETTPYEPSSPYSASKASSDHL 177 + S+ VYG +P + + P S Y+A+K +++ + Sbjct: 120 ---------HLLYASSSSVYGLNRK---------MPFSTDDSVDHPVSLYAATKKANELM 161 Query: 178 VRAWLRTYGLPTMVTNCSNNYGPYHFPEKLIPLVILNALEGKDLPIYGKGDQIRDWLFVE 237 + YGLP YGP+ P+ + LEGK + +Y G RD+ +++ Sbjct: 162 AHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYID 221 Query: 238 DHARALYKVI------------------TEGKVGETYNIGGHNEKKNIEVVNTICEILDT 279 D A A+ ++ YNIG + + ++ + + + L Sbjct: 222 DIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI 281 Query: 280 LVPKQTAYSEQITYVQDRPGHDRRYAIDSSKMQRELNWTPEETFETGLRKTVQWYLDN 337 K + +PG + D+ + + +TPE T + G++ V WY D Sbjct: 282 EAKKN--------MLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 45.5 bits (108), Expect = 1e-07 Identities = 46/213 (21%), Positives = 85/213 (39%), Gaps = 33/213 (15%) Query: 3 NVLLLGESGFVGSVVYNSL----HCVCKVYTIAPNKKITI--DNVFEVANDVFKSIEIN- 55 L+ G +GF+G V L H V + + +++ + +A F+ +I+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 56 -------------NIDVVINCIAMANLDQCENNKLDCELVNTTFVTHIVDYLKDKDIK-L 101 + + V + N N T +I++ + I+ L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 102 VHISSNAVYDGLNA--PYSE-NSLREPINYYGICKSNADYYIESNLNNYAIA----RPIT 154 ++ SS++VY GLN P+S +S+ P++ Y K + + + Y + R T Sbjct: 122 LYASSSSVY-GLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFT 180 Query: 155 VYGPRKIEQR-DNPVSFIVKKILSGESFDLVDD 186 VYGP R D + K +L G+S D+ + Sbjct: 181 VYGPW---GRPDMALFKFTKAMLEGKSIDVYNY 210
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 30.1 bits (68), Expect = 0.028 Identities = 15/106 (14%), Positives = 40/106 (37%), Gaps = 15/106 (14%) Query: 83 LGCVEGVILAELLLMVRDDIQILANQYLKTVPELDQLFIGVDVFEGKDAVKSNMKALRAA 142 + GV +A+ + + ++ I E+++L + K ++A++ Sbjct: 8 IAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLT------AALEKSKEELRAIK-- 59 Query: 143 NKHLANGGLLLVFPAGEVSQLVDAKQQRLEDKEWSRSVSALIRKNK 188 ++ A+ G + +++ A L+D E + I + Sbjct: 60 DQTEASMG-------ADKAEIFAAHLLVLDDPELVDGIKGKIENEQ 98
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 35.5 bits (82), Expect = 6e-04 Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 2/40 (5%) Query: 512 RVDTYTALQAMTIWPAYQHFEESYKGSIEVGKNADLIILD 551 RV Y A TI PA H GS+EVGK ADL++ + Sbjct: 401 RVKRYIA--KYTINPAIAHGLSHEIGSLEVGKRADLVLWN 438
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 78.4 bits (193), Expect = 1e-19 Identities = 56/201 (27%), Positives = 82/201 (40%), Gaps = 24/201 (11%) Query: 1 MKSNVVTLVGLFSLTTFSTLSYAADSKDHGVYVGANYGY------LKVDGQDDFDDDSDA 54 MK + + +L F+T++ AA KD+ Y GA G+ ++ ++ Sbjct: 1 MKKTAIAIA--VALAGFATVAQAAP-KDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLG 57 Query: 55 MQALVGYRFNRYLALEGGYIDFGSY---GNNLANA-ETDGYTAALKVTAPITDRVDVYAK 110 A GY+ N Y+ E GY G G+ A + G K+ PITD +D+Y + Sbjct: 58 AGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTR 117 Query: 111 GGQMWYSTDYNVAGFHGNKDDEGV--FAGAGVGFKVTDNFLVNAEYTWYDVELNAENVFD 168 G M + D + +G D GV GV + +T EY W N+ D Sbjct: 118 LGGMVWRADTK-SNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQW------TNNIGD 170 Query: 169 GA--NTNTDFKQASLGVEYRF 187 T D SLGV YRF Sbjct: 171 AHTIGTRPDNGMLSLGVSYRF 191
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 28.2 bits (63), Expect = 0.021 Identities = 24/119 (20%), Positives = 52/119 (43%), Gaps = 6/119 (5%) Query: 8 VTEEELDQIIEEAEKVEAAAQEAEAELEEIGDEKDAKIAQLEAALLSSETKVKDQQDAVL 67 + + + + E EK+ AA ++++ EL I D+ +A + +A + ++ V D + V Sbjct: 29 IEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKAEIFAAHLLVLDDPELVD 88 Query: 68 RAKAEVENMRRRTEQEIDKARKYALNKFAEELLPVIDNL--ERAIQAADTENEVIKPIL 124 K ++EN + E + + + F + + ERA D V+ ++ Sbjct: 89 GIKGKIENEQMNAEYALKEVS----DMFVSMFESMDNEYMKERAADIRDVSKRVLGHLI 143
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 139 bits (351), Expect = 2e-38 Identities = 81/385 (21%), Positives = 145/385 (37%), Gaps = 81/385 (21%) Query: 5 IGIDLGTTNSCVAVLDG----DKPRVIE-NAEGERTTASVIAYTDGETLVGQPAKRQAVT 59 + IDLGT N+ + V ++P V+ + + SV A VG AK+ Sbjct: 13 LSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAA-------VGHDAKQMLGR 65 Query: 60 NPTNTLFAIKRLIGRRFEDEEVQRDIEIMPYKIVKADNGDAWVEAKGQKMAAPQVSAEVL 119 P N + AI+ + D V + ++L Sbjct: 66 TPGN-IAAIRPMKDGVIADFFV---------------------------------TEKML 91 Query: 120 KK-MKKTAEDFLGEEVTGAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAY 178 + +K+ + ++ VP +R+A +++ + AG +I EP AAA+ Sbjct: 92 QHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGA 151 Query: 179 GLDKKGGDRTIAVYDLGGGTFDISIIEIDEVEGEKTFEVLATNGDTHLGGEDFDNRLINY 238 GL V D+GGGT ++++I ++ V + +GG+ FD +INY Sbjct: 152 GLPVS-EATGSMVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEAIINY 201 Query: 239 LVDEFKKEQGIDLKNDPLAMQRVKEAAEKAKIELSSTSQTD----VNLPYVTADATGPKH 294 + + G + AE+ K E+ S D + + P+ Sbjct: 202 VRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRG 248 Query: 295 MNIKVTRAKLESLVEDLVQRSLEPLKVALADA--DLSVNDITD--VILVGGQTRMPMVQA 350 + + LE+L E L + + VAL +L+ +DI++ ++L GG + + Sbjct: 249 FTLN-SNEILEALQEPLTG-IVSAVMVALEQCPPELA-SDISERGMVLTGGGALLRNLDR 305 Query: 351 KVAEFFGKEARRDVNPDEAVAMGAA 375 + E G +P VA G Sbjct: 306 LLMEETGIPVVVAEDPLTCVARGGG 330
>PF07132#Harpin protein (HrpN) Length = 356 Score = 30.0 bits (67), Expect = 0.016 Identities = 16/38 (42%), Positives = 19/38 (50%) Query: 76 QGGGGFGGGFGGGGADFGDIFGDVFGDIFGGGRRGGGG 113 GGG GGG GG G+ G + G + G GGG G Sbjct: 64 MMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLG 101 Score = 29.7 bits (66), Expect = 0.020 Identities = 17/43 (39%), Positives = 19/43 (44%) Query: 78 GGGFGGGFGGGGADFGDIFGDVFGDIFGGGRRGGGGHRAQRGA 120 G GGG GGG G G + G + GGG GG G G Sbjct: 62 GSMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLGSGL 104
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 45.6 bits (108), Expect = 4e-09 Identities = 14/53 (26%), Positives = 34/53 (64%) Query: 12 KRLRGMTLIELLIAVTIVGIIAAIAYPSYTNHVIKSHRTVALSDLSRIQLELE 64 + RG TL+E+++ + I+G++A++ P+ + K+ + A+SD+ ++ L+ Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALD 57
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.5 bits (79), Expect = 8e-05 Identities = 10/25 (40%), Positives = 17/25 (68%) Query: 17 RGFTLLELMITVAVLSALLATAAPS 41 RGFTLLE+M+ + ++ L + P+ Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPN 32
>FLAGELLIN#Flagellin signature. Length = 507 Score = 185 bits (470), Expect = 7e-56 Identities = 90/370 (24%), Positives = 162/370 (43%), Gaps = 10/370 (2%) Query: 2 AVTVSTNVSAMTAQRYLNKATNELNTSMERLSSGHKINSAKDDAAGLQISNRLTAQSRGL 61 A ++TN ++ Q LNK+ + L++++ERLSSG +INSAKDDAAG I+NR T+ +GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DVAMRNANDGISIAQTAEGAMNEATSVMQRMRDLAIQSSNGTNSPAERQAINEESMALVD 121 A RNANDGISIAQT EGA+NE + +QR+R+L++Q++NGTNS ++ ++I +E ++ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 ELNRIAETTSFGGRRLLNGSFGEAAFQIGASSGEAMIMGLTSIRADDTRMGGVTFFSEVG 181 E++R++ T F G ++L+ Q+GA+ GE + + L I + G Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ-MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 KGKDWGVDPTKADLKITLPGMGEDEDGNVDDLEININAKAGDDIEELATYINGQSDMINA 241 + + +++N+ A T + Sbjct: 180 ATVGD------LKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAAN 233 Query: 242 SVSEDGKLQIFVAHPNVQGDISISGGLASELGLSDEPVRTSVQDIDMTTVQGSQNAISVL 301 + A + S +G ++ D V + + + Sbjct: 234 GQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGN 293 Query: 302 DSALK---YVDSQRADLGAKQNRLSHSINNLANIQENVDASNSRIKDTDFAKETTQMTKA 358 D K ++ ++ L + + A +Q + + S + + T+ A Sbjct: 294 DGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESA 353 Query: 359 QILQQAGTSI 368 ++ + Sbjct: 354 KLSDLEANNA 363 Score = 137 bits (346), Expect = 3e-38 Identities = 70/243 (28%), Positives = 114/243 (46%), Gaps = 24/243 (9%) Query: 160 GLTSIRADDTRMGGVTFFSEVGKGKDWGVDPTKADLKITLPGMGEDEDGNVDDLEININA 219 G D + T ++ G + V T K+TL ++ N++A Sbjct: 271 GGKEGDTFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTL------TVADITAGAANVDA 324 Query: 220 KAGDDIEEL-ATYINGQSDMINASVSEDGKLQIFVAHPNVQGDISISGGLASELGLSDEP 278 + + + +NGQ + + +E KL A+ V+G+ I+ A + Sbjct: 325 ATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGD 384 Query: 279 VRT-----------------SVQDIDMTTVQGSQNAISVLDSALKYVDSQRADLGAKQNR 321 T + + + + N ++ +DSAL VD+ R+ LGA QNR Sbjct: 385 KVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNR 444 Query: 322 LSHSINNLANIQENVDASNSRIKDTDFAKETTQMTKAQILQQAGTSILAQAKQLPNSAMS 381 +I NL N N++++ SRI+D D+A E + M+KAQILQQAGTS+LAQA Q+P + +S Sbjct: 445 FDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLS 504 Query: 382 LLQ 384 LL+ Sbjct: 505 LLR 507
>PF03944#delta endotoxin Length = 633 Score = 25.8 bits (56), Expect = 0.010 Identities = 9/24 (37%), Positives = 13/24 (54%) Query: 28 PFSFERTGARLVARAYVEIKRNEH 51 PFSF+ V + + E K+N H Sbjct: 23 PFSFQHKSLDTVQKEWTEWKKNNH 46
>FLAGELLIN#Flagellin signature. Length = 507 Score = 201 bits (511), Expect = 6e-62 Identities = 90/297 (30%), Positives = 144/297 (48%), Gaps = 1/297 (0%) Query: 2 AVNVNTNVSAMTAQRYLNNANSAQQTSMERLSSGFKINSAKDDAAGLQISNRLNVQSRGL 61 A +NTN ++ Q LN + S+ +++ERLSSG +INSAKDDAAG I+NR +GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DVAVRNANDGISIAQTAEGAMNETTNILQRMRDLSLQSANGSNSKAERVAIQEEVTALND 121 A RNANDGISIAQT EGA+NE N LQR+R+LS+Q+ NG+NS ++ +IQ+E+ + Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 ELNRIAETTSFGGNKLLNGTHGAKSFQIGADNGEAVMLELKDMRSDNKMMGGVSYQAESG 181 E++R++ T F G K+L+ Q+GA++GE + ++L+ + + + G + Sbjct: 121 EIDRVSNQTQFNGVKVLSQD-NQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 KGKDWNVAQGKNDLKISLTDSFGQEQEININAKAGDDIEELATYINGQTDLVKASVDQDG 241 + KN + +++N+ A T + Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 242 KLQIFAGNNKVEGEVSFSGGLSGELGLGDDKKNVTVDTIDVTSVGGAQESVAIIDAA 298 + + + S +G + G K DT D V ++ D Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGN 296 Score = 135 bits (342), Expect = 1e-37 Identities = 82/377 (21%), Positives = 144/377 (38%), Gaps = 20/377 (5%) Query: 19 NNANSAQQTSMERLSSGFKINSAKDDAAGLQISNRLNVQSRGLDVAVRNANDGISIAQTA 78 N Q + ++ G L + ++ + + Sbjct: 132 NGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATVGDLKSSFKN 191 Query: 79 EGAMNETTNILQRMRDLSLQSANGSNSKAERVAIQEEVTALNDELNRIAETTSFGGNKLL 138 + + R A +++ A V + V A N +L + + Sbjct: 192 VTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAENNTAVDLFK 251 Query: 139 NGTHGAKSFQIGADNGEAVMLELKDMRSDNKMMGGVSYQAESGKGKDWNVAQGKNDLKIS 198 A + + A G + D + ++G + V+ N K++ Sbjct: 252 TTKSTAGTAEAKAIAGAIKGGKEGDTFDYKG--VTFTIDTKTGNDGNGKVSTTINGEKVT 309 Query: 199 LTDSFGQEQEININAKAGDDIEEL-ATYINGQTDLVKASVDQDGKLQIFAGNNKVEGEVS 257 LT + N++A + + + +NGQ + ++ KL NN V+GE Sbjct: 310 LTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESK 369 Query: 258 FSGGLSGELGLGDDKK-----------------NVTVDTIDVTSVGGAQESVAIIDAALK 300 + + K + ++ + +A ID+AL Sbjct: 370 ITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALS 429 Query: 301 YVDSHRAELGAFQNRFNHAISNLDNINENVNASKSRIKDTDFAKETTAMTKSQILSQASS 360 VD+ R+ LGA QNRF+ AI+NL N N+N+++SRI+D D+A E + M+K+QIL QA + Sbjct: 430 KVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGT 489 Query: 361 SILAQAKQAPNSALSLL 377 S+LAQA Q P + LSLL Sbjct: 490 SVLAQANQVPQNVLSLL 506
>FLAGELLIN#Flagellin signature. Length = 507 Score = 149 bits (376), Expect = 2e-42 Identities = 80/354 (22%), Positives = 132/354 (37%), Gaps = 17/354 (4%) Query: 5 NTNVAAMMTQRHLSQAADQNVESQRNLSSGYRINSASDDAAGLQISNTLHVQTRGIDVAL 64 NTN +++TQ +L+++ + LSSG RINSA DDAAG I+N +G+ A Sbjct: 5 NTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAS 64 Query: 65 RNAHDAYSVAQTAEGALHESSDILQRLRSLGLQAANGSHEQDDRKSLQQEVIALQDELDR 124 RNA+D S+AQT EGAL+E ++ LQR+R L +QA NG++ D KS+Q E+ +E+DR Sbjct: 65 RNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDR 124 Query: 125 VAITTTFADKNLFNGSYGSQSFHIGANANS-ISLALRNMRTHIPEMGGQHYLGDSL-DKD 182 V+ T F + + +GAN I++ L+ + + G + G Sbjct: 125 VSNQTQFNGVKVLSQD-NQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATVG 183 Query: 183 WRVTRDNQQFAFEYQDNEGQAQSKVLTLKVGDNLEEVATYINAQQSVVDASVTQDHQLQF 242 + ++ + T + + Sbjct: 184 DLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAEN 243 Query: 243 FTSTLNAPEGITWKGNFADEMDIGSGELVTVDDLDMSTVGGAQLAIGVVDAAIKYVDSHR 302 T+ + G + G+ + D G I Sbjct: 244 NTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEG--DTFDYKGVTFTIDTKTGNDG------ 295 Query: 303 SEIGGFQNRVSGTIDNLNTINRSVSESKGRIRDTDFARESTVMVRSQVLQDATT 356 +VS TI+ + G +S+ V + V+ T Sbjct: 296 ------NGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFT 343 Score = 100 bits (250), Expect = 2e-25 Identities = 46/216 (21%), Positives = 86/216 (39%), Gaps = 19/216 (8%) Query: 177 DSLDKDWRVTRDNQQFAFEYQDNEGQAQSKVLTLKVGDNLEE-VATYINAQQSVVDASVT 235 D + +V+ + A + + + + + +N Q + D + Sbjct: 291 TGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKN 350 Query: 236 QDHQLQFFTSTLNAPEGITWKGNFADEMDIGSGELVTVD------------------DLD 277 + +L + N A+ +G+ VT+ + Sbjct: 351 ESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDA 410 Query: 278 MSTVGGAQLAIGVVDAAIKYVDSHRSEIGGFQNRVSGTIDNLNTINRSVSESKGRIRDTD 337 + + +D+A+ VD+ RS +G QNR I NL +++ ++ RI D D Sbjct: 411 AAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDAD 470 Query: 338 FARESTVMVRSQVLQDATTALLAQAKQRPSSALGLL 373 +A E + M ++Q+LQ A T++LAQA Q P + L LL Sbjct: 471 YATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 754 bits (1949), Expect = 0.0 Identities = 284/571 (49%), Positives = 409/571 (71%), Gaps = 2/571 (0%) Query: 1 MISGILASPGIAIGKALLLQEDEIVLNTNTISDDQVEAEVARFFDARNKSAAQLETIKQK 60 I+GI AS G+AI KA + E + + +I+D V E+ + A KS +L IK + Sbjct: 4 KITGIAASSGVAIAKAFIHLEPNVDIEKTSITD--VSTEIEKLTAALEKSKEELRAIKDQ 61 Query: 61 ALETFGEEKEAIFEGHIMLLEDEELEEEILALIKNDKMTADHAIHSVIEEQACALESLDD 120 + G +K IF H+++L+D EL + I I+N++M A++A+ V + ES+D+ Sbjct: 62 TEASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDN 121 Query: 121 EYLKERATDIRDIGSRFVKNALGINIVSLSDINEEVILVAYDLTPSETAQINLDYVLGFA 180 EY+KERA DIRD+ R + + +G+ SL+ I EE +++A DLTPS+TAQ+N +V GFA Sbjct: 122 EYMKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFA 181 Query: 181 CDIGGRTSHTSIMARSLELPAIVGTNDITKKVKNGDMLILDAMNNKIVVNPSEAEVEEAK 240 DIGGRTSH++IM+RSLE+PA+VGT ++T+K+++GDM+I+D + ++VNP+E EV+ + Sbjct: 182 TDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYE 241 Query: 241 AVKAAFLAEKEELAKLKDLHAETTDGHRVEVCGNIGTVKDCDGIIRNGGEGVGLYRTEFL 300 +AAF +K+E AKL + T DG VE+ NIGT KD DG++ NGGEG+GLYRTEFL Sbjct: 242 EKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFL 301 Query: 301 FMDRTALPTEEEQYQAYKEVAEAMNGQAVIIRTMDIGGDKDLPYMDLPQEMNPFLGWRAV 360 +MDR LPTEEEQ++AYKEV + M+G+ V+IRT+DIGGDK+L Y+ LP+E+NPFLG+RA+ Sbjct: 302 YMDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAI 361 Query: 361 RISLDRREILRDQLRGILRASAHGKLRIMFPMIISVEEIRELKNAIEEYKAELRAEGLAF 420 R+ L++++I R QLR +LRAS +G L++MFPMI ++EE+R+ K ++E K +L +EG+ Sbjct: 362 RLCLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDV 421 Query: 421 DENIEIGVMVETPAAAAIAHHLAKEVSFFSIGTNDLTQYTLAVDRGNEMISHLYNPLSPA 480 ++IE+G+MVE P+ A A+ AKEV FFSIGTNDL QYT+A DR NE +S+LY P PA Sbjct: 422 SDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPA 481 Query: 481 VLTVIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSGISIPKVKKVIRNS 540 +L ++ VI A+H+EGKW GMCGE+AGDE A LLLG+GLDEFSMS SI + + Sbjct: 482 ILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKL 541 Query: 541 NFAEVKAMAEEALSLPTAAEIEAVVEKFIAE 571 + E+K A++AL L TA E+E +V+K + Sbjct: 542 SKEELKPFAQKALMLDTAEEVEQLVKKTYLK 572
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 30.3 bits (68), Expect = 0.008 Identities = 12/56 (21%), Positives = 20/56 (35%), Gaps = 1/56 (1%) Query: 123 EDVAIQPSEVEEPMQEVVEEEIMPSAFDAPKQEMEMVEEVAP-AVVEQPEEPKPEP 177 + V P V EP E P ++ + + P V + E+PK + Sbjct: 59 QAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDV 114 Score = 28.4 bits (63), Expect = 0.034 Identities = 13/53 (24%), Positives = 23/53 (43%), Gaps = 5/53 (9%) Query: 133 EEPMQEVVEEEIMPSAFDAPKQEMEMVEEVAPAVVEQPE-----EPKPEPEMQ 180 EP Q V + + + + AP V+E+P+ +PKP ++Q Sbjct: 55 LEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQ 107
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 85.9 bits (212), Expect = 5e-22 Identities = 56/217 (25%), Positives = 83/217 (38%), Gaps = 13/217 (5%) Query: 3 KSILITGCSTGIGYVCAHALHKQGFHVIA----SCRKLDDVQRLQSEGLTCIQLDLD--D 56 K ITG + GIG A L QG H+ A + V L++E D D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 57 PISITSGAKQAIELAQGQLYALFNNGAYGQPGALEDLPTEALKAQFQTNFFGWHQLVQEV 116 +I + IE G + L N +PG + L E +A F N G + V Sbjct: 69 SAAIDEITAR-IEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 117 LPTMRAQGEGRIIQNSSVLGFAAMKYRGAYNASKFALEGWTDTLRLELADTDIKVALIEP 176 M + G I+ S AY +SK A +T L LELA+ +I+ ++ P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 177 GPIETQFRHNALLAFEQWIDVDSSPHRIAYDGQKKRL 213 G ET + + W D + + I + + Sbjct: 188 GSTETDMQWSL------WADENGAEQVIKGSLETFKT 218
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 46.3 bits (110), Expect = 6e-08 Identities = 31/144 (21%), Positives = 52/144 (36%), Gaps = 18/144 (12%) Query: 1 MKILLTGGTGFIGSELLKLLT--THQIV---LLTRSPDQAKQHLQYADL---------GN 46 MK L+TG GFIG + K L HQ+V L D + + + L + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 47 IEYLASLDELADLNNIDAVINLAGEPIADKRWTDQQKEKICDSRWKITEQIVELIHASTE 106 + + +L + + V R++ + DS I+E + Sbjct: 61 LADREGMTDLFASGHFERVFISPHR--LAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 107 PPSVFLSGSAVGYYGDQQDHPFDE 130 ++ S S+V YG + PF Sbjct: 119 QHLLYASSSSV--YGLNRKMPFST 140
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 57.5 bits (139), Expect = 1e-10 Identities = 22/133 (16%), Positives = 46/133 (34%), Gaps = 6/133 (4%) Query: 599 KALIVEDNRTNAIIMETFLRAKGFECSSVENGQLAVNKIAVEPFDLILMDNHMPVLDGVG 658 L+ +D+ ++ L G++ N IA DL++ D MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 659 AISAIRSMSSAAKSVLIFG-CTADVFKETQERMLGVGADHIIAKPIVESELDDALYRHAD 717 + I+ +++ T + E+ GA + KP +EL + A Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEK----GAYDYLPKPFDLTELIG-IIGRAL 119 Query: 718 LLYQYQTKQNQQA 730 + + + + Sbjct: 120 AEPKRRPSKLEDD 132
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 29.8 bits (67), Expect = 0.027 Identities = 14/72 (19%), Positives = 30/72 (41%), Gaps = 1/72 (1%) Query: 453 LRPTIENDDKFVIKDQSEVSIDKSALIDDPKALEALRYLNSIGVTGDIDELLQQVDKIPV 512 + I +D IK Q+ + + A +D ++AL+ L + + L + ++ + Sbjct: 7 MEAFIRSDQYNFIKSQAYILANGHATANDRGVIQALKSLAIEKIIHVFENLTDEQKEL-I 65 Query: 513 TKVRKRQAQRQA 524 V Q + A Sbjct: 66 DTVLTVQNREDA 77
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 30.4 bits (68), Expect = 0.039 Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 16/107 (14%) Query: 538 DQAVVLAETIKDMQESGYSYRDQAVLCSGNERLSQLAEQLEL----LGVPVLYLGSLFER 593 ++AV+L I DMQ S LS +L+ LG+PV+Y + Sbjct: 29 NRAVLL---IHDMQNYFVDAFTAG--ASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQ 83 Query: 594 EEVKDMFSFLSLLTDSWGSGLVRIGRWPEF--ELSLEDLDVILNHLR 638 +LLTD WG GL + EL+ ED D++L R Sbjct: 84 NPDDR-----ALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWR 125
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 59.9 bits (145), Expect = 6e-12 Identities = 77/376 (20%), Positives = 132/376 (35%), Gaps = 46/376 (12%) Query: 9 YKRITLSLALGSFLVFSNLYLLQPMLPTFATLFSISETQVNWLFAASTLALSFSLVPMAV 68 + +I + L + SF N +L LP A F+ NW+ A L S Sbjct: 12 HNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGK 71 Query: 69 LSESIGRKPVMMVGLFSIPAISALMLLGDSFIF-LVACRALIGIALAAFAAVAVAYMAEE 127 LS+ +G K +++ G+ S + +G SF L+ R + G AAF A+ + +A Sbjct: 72 LSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARY 131 Query: 128 LDKHAFSMAIGTYIAANSLGGIAGRISGGLLADNFSVDVAIEVMMVVTLIGVICVHYLLP 187 + K A G + ++G G GG++A + + M +T+I V + LL Sbjct: 132 IPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITVPFLMKLLK 190 Query: 188 KQRN----------------------FTPSSSSL-------------RHQNRAI-----I 207 K+ FT S S +H + Sbjct: 191 KEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDP 250 Query: 208 GHFRNQRVWFAMLIGGLNFALFVNLYSVMGFRLVSAPHNVPVGLAS-LIFICYLGGTFSS 266 G +N +L GG+ F S++ + + + S +IF + Sbjct: 251 GLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFG 310 Query: 267 RCAGHWSKRYSSILGMFLGAVVSMAGMWIAAF---ESLAAMLISLLLISFGAFFTHTLAY 323 G R + + +G A+F + M I ++ + G FT T+ Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVIS 370 Query: 324 GWVGQNATQAKATATA 339 V + Q +A A Sbjct: 371 TIVSSSLKQQEAGAGM 386
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 38.5 bits (89), Expect = 3e-05 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Query: 23 SACALSLFSGSAAADDKELVFMNWGPYINSNILEQFTKETGIKVIYSTYESNETLYAKLK 82 + +SL S ++ V N+ YI+ +LE+ + + + TY SNE L Sbjct: 10 FSLFVSLSSILSSCGSTTFVLANFESYISPLLLER--VQEKHPLTFLTYPSNEKLINGFA 67 Query: 83 THNQGYDLVVPSTYFVAKMRDEGMLQKIDKTKL 115 N Y + V STY V+++ + +L ID ++ Sbjct: 68 --NNTYSVAVASTYAVSELIERDLLSPIDWSQF 98
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 28.5 bits (63), Expect = 0.029 Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 12/91 (13%) Query: 146 LPEALVLTQAANESAWGTSRFATQ----ANNLFGQWCYKQGCGIVPAQRAAGKTHEVQK- 200 +P L+L QAA ES WG + + + NLFG G V + K Sbjct: 169 VPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKK 228 Query: 201 -------FDSVQQSIHGYFMNVNRNPAYADL 224 + S +++ Y + RNP YA + Sbjct: 229 VKAKFRVYSSYLEALSDYVGLLTRNPRYAAV 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.6 bits (173), Expect = 5e-15 Identities = 23/118 (19%), Positives = 52/118 (44%), Gaps = 2/118 (1%) Query: 458 LLIVEDTQSNQLVIKLILNKLGHNVHIASHGAEALTFLEENDTRIDMILMDVSMPVMDGI 517 +L+ +D + + V+ L++ G++V I S+ A ++ D+++ DV MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA--AGDGDLVVTDVVMPDENAF 63 Query: 518 TATRLIRKKGITIPIVALTAHALESDKDKCLDAGMDSFVSKPVRRQDIYEAIQSLIET 575 I+K +P++ ++A K + G ++ KP ++ I + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 26.9 bits (59), Expect = 0.045 Identities = 15/65 (23%), Positives = 22/65 (33%), Gaps = 11/65 (16%) Query: 81 VEQLEVSDAVTIDVELPTVEPVPEIVASTDMHSIAVAEPVEAPSVETEPPTEPEPVKKPP 140 +E + +++ + P P+ V P P VE EP EP P Sbjct: 36 IELPAPAQPISVTMVTPADLEPPQAVQ-----------PPPEPVVEPEPEPEPIPEPPKE 84 Query: 141 FPVKK 145 PV Sbjct: 85 APVVI 89
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 58.1 bits (140), Expect = 4e-10 Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 14/139 (10%) Query: 2082 NLIMGTDGDDILVGTDGNDMIIGGLGNDILTGGEGDDVFKWTEMQSATDTVTDFSDGDQL 2141 + + G +GDD L G DGND +IG GN+ L GG+GDD F+ A + L Sbjct: 765 DTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQGNSLAK---------NVL 815 Query: 2142 DFTDVFDDMTGTDISALLDDLGSGDY--RGRVDDITVEVTESGGNSTLTINKDGQQL--- 2196 D + G++ + LLD D G +DI ++ G + +L Sbjct: 816 FGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKEDKLSLA 875 Query: 2197 EVNFDGASAADIANSLISN 2215 +++F + N LI Sbjct: 876 DIDFRDVAFKREGNDLIMY 894 Score = 49.6 bits (118), Expect = 1e-07 Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 1/81 (1%) Query: 2072 YQTMALNSELNLIMGTDGDDILVGTDGNDMIIGGLGNDILTGGEGDDVFKWTEMQSATDT 2131 +Q + N++ G G+D L G++G D++ GG G+D+L GG G+D++++ Sbjct: 803 FQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHII 862 Query: 2132 VTDFSDGDQLDFTDV-FDDMT 2151 D D+L D+ F D+ Sbjct: 863 DDDGGKEDKLSLADIDFRDVA 883 Score = 38.4 bits (89), Expect = 4e-04 Identities = 16/34 (47%), Positives = 21/34 (61%) Query: 2086 GTDGDDILVGTDGNDMIIGGLGNDILTGGEGDDV 2119 G+ DI G DG+D+I G GND L G +G+D Sbjct: 733 GSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDT 766
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 82.3 bits (203), Expect = 8e-21 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 11/123 (8%) Query: 87 QMQIRVLFANDSDEINPVFAKQIRELSDFLKEY--PSTSIELQGYASRTGGSEHNLDLSK 144 ++ VLF + + P + +L L S+ + GY R G +N LS+ Sbjct: 216 TLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSE 275 Query: 145 RRAENVRKALLQNGITPDRVTIVGYGDT-VLATTGTDEVSH--------ALNRRVTATVV 195 RRA++V L+ GI D+++ G G++ + D V A +RRV V Sbjct: 276 RRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVK 335 Query: 196 GHK 198 G K Sbjct: 336 GIK 338
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 73.5 bits (180), Expect = 7e-15 Identities = 38/142 (26%), Positives = 54/142 (38%), Gaps = 13/142 (9%) Query: 3085 DQADTIYGGAGNDILFGQGGNDKLFGGADNDILIGGLGSDILTGGDGEDIFKWID----V 3140 + GG+GNDIL G ++ L GGA ND+L GG G+D L GG G D F + Sbjct: 338 VTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDST 397 Query: 3141 ANERDTVTDFSSSEDSLDFSDL-------FDDLSKDEVGDLLSDLQSGSHTGDAGGYHVE 3193 D + DF D +D S F G + + + Sbjct: 398 VAAYDWIADFQKGIDKIDLSAFRNEGQLSFVQDQFTGKGQEV--MLQWDAANSITNLWLH 455 Query: 3194 VSQDGSTDTNLSITKGSSTLDI 3215 + S D + I ++ DI Sbjct: 456 EAGHSSVDFLVRIVGQAAQSDI 477
>PF05844#YopD protein Length = 295 Score = 227 bits (580), Expect = 4e-75 Identities = 74/238 (31%), Positives = 135/238 (56%), Gaps = 5/238 (2%) Query: 97 IKSPSDAVSQSLSLLTLLYQVSKLSREQQVLQREIAVEANVASLQSQAAELNNSASAMIA 156 +++ + S+ LL +L+++++ +RE VLQR+ +A + + ++Q E+ + A+ MIA Sbjct: 63 MEAAGSELDSSVELLLILFRIAQKARELGVLQRDNENQAIIHAQKAQVDEMRSGATLMIA 122 Query: 157 MAVVSGVLAGATAIIGALGSFKAGKEIKTEMASNNVLKTQKAGFDQVEELMNNGNLSKTQ 216 MAV++GV A A+A++G+LG+ K GK I E + + D + + + Sbjct: 123 MAVIAGVGALASAVVGSLGALKNGKAISQEKTLQKNIDGRNELIDAKMQALGK----TSD 178 Query: 217 QDQVKRAHSLAKDSIADTTAQLTSGGRKFDKLMSSNQAKNAILQALGQMANSASNVEQTK 276 +D+ A D D+ A L + GR F+ + Q N ++Q+ QMAN++ V Q + Sbjct: 179 EDRKIVGKVWAADQAQDSVA-LRAAGRAFESRNGALQVANTVIQSFVQMANASVQVRQGE 237 Query: 277 AQARSKDDEVQATRAQAAKQKADENIGFQEGLLKELRELFRSISDSQNQAWRASIPTV 334 +QA ++++EV AT Q+ KQK ++ + F G +K++ +L + + S NQAWRA+ V Sbjct: 238 SQASAREEEVNATIGQSQKQKVEDQMSFDAGFMKDVLQLIQQYTQSHNQAWRAAAGVV 295
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 31.6 bits (71), Expect = 0.006 Identities = 67/381 (17%), Positives = 139/381 (36%), Gaps = 47/381 (12%) Query: 56 KVQLDAPNAAVSDKVTDLTLKAMAQLQKIVDTIAKALHAVADQTGSIAVKIIAGSADDFE 115 K LD A TD KA + A A +Q ++ A Sbjct: 199 KEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAASQNQVSQGEQDNLSNVARLTM 258 Query: 116 VELAAITDKLKSAQNELKIQEVKVAKAKHEQEMAENQEKIKESEAAAKEAQKS----GLA 171 + I K+ + L+ ++ + A E AE ++K E + ++A+++ G Sbjct: 259 LMAMFIEIVGKNTEESLQ-NDLALFNALQEGRQAEMEKKSAEFQEETRKAEETNRIMGCI 317 Query: 172 AKIFGWISAVVSIVVGAIMVATGVGAAAG--ALMIAGGVMGAVS---------------- 213 K+ G + +VS+V + AA A+M+A ++ A + Sbjct: 318 GKVLGALLTIVSVVAAVFTGGASLALAAVGLAVMVADEIVKAATGVSFIQQALNPIMEHV 377 Query: 214 ----MALQEPAVQDALKEAGVN---VDVLNKVVMALEIAVAVIGAIVTFGGAAAGGIAKL 266 M L A+ AL+ GV+ ++ +V A+ A+A++ IV G AKL Sbjct: 378 LKPLMELIGKAITKALEGLGVDKKTAEMAGSIVGAIVAAIAMVAVIVVVAVVGKGAAAKL 437 Query: 267 AAKSASKIAQKVTDIATKAAANMAKVAD-------------MGSKAATTTAKAIRYGAET 313 + + + + + +A+ +G+ + + E Sbjct: 438 GNALSKMMGETIKKLVPNVLKQLAQNGSKLFTQGMQRITSGLGNVGSKMGLQTNALSKEL 497 Query: 314 VDLTVN----IGKGATDSVHAANNANVTEIQADITDLRAKMTLSQAVIDKLKEEIGKLME 369 V T+N + + +A + ++ A L++ +D++++ + + +E Sbjct: 498 VGNTLNKVALGMEVTNTAAQSAGGVAEGVFIKNASEALADFMLARFAMDQIQQWLKQSVE 557 Query: 370 DFQELMSIIMQMIQAKSETMQ 390 F E + ++ +A S +Q Sbjct: 558 IFGENQKVTAELQKAMSSAVQ 578
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 153 bits (389), Expect = 1e-50 Identities = 76/154 (49%), Positives = 112/154 (72%) Query: 7 TDPSQMQAEELLSFLEEGGTLKMLHDVSADTIEHIYAVGYNFFQSGKIEQAAKVFQLLSM 66 T +Q + SFL+ GGT+ ML+++S+DT+E +Y++ +N +QSGK E A KVFQ L + Sbjct: 5 TTDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCV 64 Query: 67 LDHYQARFFIGLGAARQELGEYLQAIDAYSYAALVDINDPRPPFHSAECHLKLEQLTEAE 126 LDHY +RFF+GLGA RQ +G+Y AI +YSY A++DI +PR PFH+AEC L+ +L EAE Sbjct: 65 LDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAE 124 Query: 127 SGFYSAKEMSAGKSQYADLHQRAGIMLEAVRNKR 160 SG + A+E+ A K+++ +L R MLEA++ K+ Sbjct: 125 SGLFLAQELIADKTEFKELSTRVSSMLEAIKLKK 158
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 114 bits (287), Expect = 3e-30 Identities = 76/233 (32%), Positives = 127/233 (54%), Gaps = 20/233 (8%) Query: 392 GALKDRLLNITEQEKKDLEVRAEHSLTARDLLAVVESSI-GDRFDEQVLFALNERRVNRL 450 G ++L N ++ K+ LE R +AV+ S+ DR D+ +L + + + Sbjct: 88 GHYDNQLQNGIKRVKEFLESSPNTQWELRAFMAVMHFSLTADRIDDDILKVIVDSMNHHG 147 Query: 451 EKRNEQKEALQDLTVQLKIFGVVQSKIHSTQSVDGTYKPDDNAFSASDFNYNSVTD---F 507 + R++ +E L +LT +LKI+ V+Q++I+ S GT D + + D N TD F Sbjct: 148 DARSKLREELAELTAELKIYSVIQAEINKHLSSSGTINIHDKSINLMDKNLYGYTDEEIF 207 Query: 508 QNSPEYKYL------------TDNGITTHTDFL----KKQGVTVADGASFKDEEKTKKLS 551 + S EYK L ++ I + DFL K+ G S+ + +LS Sbjct: 208 KASAEYKILEKMPQTTIQVDGSEKKIVSIKDFLGSENKRTGALGNLKNSYSYNKDNNELS 267 Query: 552 NFSSSVSDKSKLLNDEVQIKTTELNDISSQYNSTVEAMNKFVQKYHSILQEIL 604 +F+++ SDKS+ LND V KTT+L+DI+S++NS +EA+N+F+QKY S++Q +L Sbjct: 268 HFATTCSDKSRPLNDLVSQKTTQLSDITSRFNSAIEALNRFIQKYDSVMQRLL 320
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 269 bits (688), Expect = 5e-92 Identities = 96/298 (32%), Positives = 163/298 (54%), Gaps = 6/298 (2%) Query: 1 MSIINSQIATNTKFDASVRNGLESSRADSAVKGSYRGETVRVHNAT-QSLFDAMEELTSL 59 M+ +++ NT R + SS+ + G +RGE+V++ + T QS+ D EE+T + Sbjct: 1 MTTLHNLSYGNTPLHNE-RPEIASSQIVNQTLGQFRGESVQIVSGTLQSIADMAEEVTFV 59 Query: 60 GSEKAEKDLTKRKIKDGGVRVNEAHELVSDYLRKVPDLEKNQKIKDLAAKMAGGNISTIA 119 SE+ E L KRK+ D RV++ E V+ YL KVP+LE+ Q + +L + ++ +++ Sbjct: 60 FSERKELSLDKRKLSDSQARVSDVEEQVNQYLSKVPELEQKQNVSELLSLLSNSPNISLS 119 Query: 120 QLQAYLNGFSEEKSHQYLALKAVKKYLSANPESKHLLALIDQAILKIEQNPDSWSQIDTE 179 QL+AYL G SEE S Q+ L ++ L PE HL L++QA++ + + + Sbjct: 120 QLKAYLEGKSEEPSEQFKMLCGLRDALKGRPELAHLSHLVEQALVSMAEEQGETIVLGAR 179 Query: 180 IRVSHFADEFSKEQEFSSLHQLRGFYRDTVHSYQGLGSAYQDVVERFGEQEVSTAVDFML 239 I + + + + L LR YRD V YQG+ + + D+ +RF ++ + + F+ Sbjct: 180 ITPEAYRES---QSGVNPLQPLRDTYRDAVMGYQGIYAIWSDLQKRFPNGDIDSVILFLQ 236 Query: 240 QGMSADLSVQGSNIDSVKLQLLMSDMQKLKTLNTLQDQVGRLFQMFKPERMSHGLSGF 297 + +SADL Q S KL +++SD+QKLK ++ DQV +Q F E ++G+ F Sbjct: 237 KALSADLQSQQSGSGREKLGIVISDLQKLKEFGSVSDQVKGFWQFFS-EGKTNGVRPF 293
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.3 bits (65), Expect = 0.007 Identities = 18/137 (13%), Positives = 37/137 (27%), Gaps = 7/137 (5%) Query: 13 ADRADKAVQRQEYRVANVAAELQKAERSVADYHVWRQEEEERRFAKAKQQTVLLKELETL 72 +++ Q VA +E ++ + + ++EE+ + K Q + + Sbjct: 1071 EAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQ----EVPKVT 1126 Query: 73 RQEIALLREREAELKQRVAE---VKVTLEQERTLLKQKQQEALQAHKTKEKFVQLQQQEI 129 Q + E Q +E + Q K V+ E Sbjct: 1127 SQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTES 1186 Query: 130 AEQSRQQQYQEELEQEE 146 + E E Sbjct: 1187 TTVNTGNSVVENPENTT 1203
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.5 bits (76), Expect = 0.002 Identities = 39/245 (15%), Positives = 92/245 (37%), Gaps = 6/245 (2%) Query: 9 TPSTQPHSPQSPMPIDDHAMLQSRFERALKENPDQTKPQPNETNNQAALEAKKPFTENYS 68 T T P++ Q+ +P ++ + E A + P P + A+ E+ + Sbjct: 995 TNITTPNNIQADVP----SVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKT 1050 Query: 69 ERSLASLHSTGSNQRKTAEKSAFAQNNDVVTENINNESDTSSPIALNTQDKMPSDMDANM 128 + + Q + K A + N +S + + T+ K + ++ Sbjct: 1051 VEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEE 1110 Query: 129 KPDIRIPTTGDK-KLPMEPSNKREKNADEQDAFERLVEDHDDSKTELAAAKTAESHESTQ 187 K + T + K+ + S K+E++ Q E E+ + ++T + ++ Q Sbjct: 1111 KAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQ 1170 Query: 188 SPKDT-KHIPTAGTKPNTVETVSDALASTLASTTVASATSASLASHPVTSTVHKTATKTE 246 K+T ++ T+ TV T + + + +T + + + S H+ + ++ Sbjct: 1171 PAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSV 1230 Query: 247 VNKHE 251 + E Sbjct: 1231 PHNVE 1235 Score = 29.3 bits (65), Expect = 0.044 Identities = 29/201 (14%), Positives = 59/201 (29%), Gaps = 5/201 (2%) Query: 33 FERALKENPDQTKPQPNETNNQAALEAKKPFTENYSERSLASLHSTGSNQRKTAEKSAFA 92 + + QT + +AK + + S S Q +T + A Sbjct: 1086 AQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEP 1145 Query: 93 QNNDVVTENINNESDTSSPIALNTQDKMPSDMDANMKPDIRIPTTGDKKLPMEPSNKREK 152 + T NI ++ A Q + +N++ + TT + + + + Sbjct: 1146 ARENDPTVNIKEPQSQTNTTADTEQPA--KETSSNVEQPVTESTTVNTGNSVVENPENTT 1203 Query: 153 NADEQDAFERLVEDHDDSKTELAAAKTAESHESTQSPKDTKHIPTAGTKPNTVETVSDAL 212 A Q E + K + + H + + T T + L Sbjct: 1204 PATTQP--TVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVL 1261 Query: 213 ASTLAST-TVASATSASLASH 232 + A VA +++ H Sbjct: 1262 SDARAKAQFVALNVGKAVSQH 1282
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 83.9 bits (207), Expect = 1e-20 Identities = 44/155 (28%), Positives = 61/155 (39%), Gaps = 12/155 (7%) Query: 170 TQHIALPVWLSLGKTHLDLNQFHSLELGDVIFFDQCYIAQQQAIVQVSNKNLWRCQLEDN 229 L + T L + +GDV+ A V K L + Sbjct: 147 MLRWPLRFVIGSSDTQRSL--LGRIGIGDVLLIRTSR-----AEVYCYAKKLGHFNRVEG 199 Query: 230 -----TLYIIEKETNMNDVNTSETLTDHQQLPVELTFDIGHQTVTLEQLNQLQPGYVFEL 284 TL I E N T+ETL QLPV+L F + + VTL +L + + L Sbjct: 200 GIIVETLDIQHIEEENNTTETAETLPGLNQLPVKLEFVLYRKNVTLAELEAMGQQQLLSL 259 Query: 285 NQPVSKPVTLRANGKIIGECELVNVNDHLGVRVLE 319 V + ANG ++G ELV +ND LGV + E Sbjct: 260 PTNAELNVEIMANGVLLGNGELVQMNDTLGVEIHE 294
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 45.6 bits (108), Expect = 4e-09 Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 5/124 (4%) Query: 3 TIQPLLDEFCRLNELPPLILEDGNRCQLLVDDRFVLYFTATEDDALMLSVAFGGLEKSGE 62 + LLD+F R E+ PL+ +D C +++D+ F L + D A + G LE + Sbjct: 5 FYKTLLDDFSRSLEMQPLVFDDHGTCNMIIDNTFALTL--SCDYARERLLLIGLLEPHKD 62 Query: 63 LRVRGLELLARANYQRVGSGNLALSLAPNGRQLVLAGRQPTEHLNSANLTVWFHEIIEQT 122 + + L L N L L P E L+ L ++E Sbjct: 63 IPQQCL-LAGALNPLLNAGP--GLGLDEKSGLYHAYQSIPREKLSVPTLKREMAGLLEWM 119 Query: 123 ELWQ 126 W+ Sbjct: 120 RGWR 123
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 31.6 bits (71), Expect = 0.006 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 4/70 (5%) Query: 25 GKLSIGGKEYTINAATQEFTRANPTSGAVARFFEATGKLFREGSTQ-SVAKAITKAVFDN 83 G+L+IGGK Y I + R NP SG + F E GK+F S+A+ +T + Sbjct: 32 GELNIGGKRYRI--IDNQVLRLNPHSG-FSLFREGVGKIFSGKMFNFSIARNLTDTLHAA 88 Query: 84 EQGQAQRLQT 93 ++ +Q L++ Sbjct: 89 QKTTSQELRS 98
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 49.0 bits (117), Expect = 1e-10 Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 6/121 (4%) Query: 1 MANGFITALMTDFAHRCQIEQLFFDGDDCCHLLIDQDTAITVRAE--DDRLTLIGLISGD 58 M+N F L+ DF+ +++ L FD C+++ID A+T+ + +RL LIGL+ Sbjct: 1 MSNLFYKTLLDDFSRSLEMQPLVFDDHGTCNMIIDNTFALTLSCDYARERLLLIGLLEPH 60 Query: 59 K--PEHDVMLQYMKASLTQGSPAVYWDEEVG-FVGFVHLSQQWLDAAILDESLGNFIEWL 115 K P+ +L L P + DE+ G + + + ++ L L + +EW+ Sbjct: 61 KDIPQQC-LLAGALNPLLNAGPGLGLDEKSGLYHAYQSIPREKLSVPTLKREMAGLLEWM 119 Query: 116 K 116 + Sbjct: 120 R 120
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 37.1 bits (85), Expect = 2e-05 Identities = 41/161 (25%), Positives = 68/161 (42%), Gaps = 22/161 (13%) Query: 51 QQAYETEKQRGYQDGLEQAKIENAQAMVATLARCNEYYLQ-----------VEHKMTNVV 99 QQ ++ Q G GLEQ E AR + + + ++ + Sbjct: 65 QQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMA 124 Query: 100 LDAVRKIIDTFDDVDTT--ISVVREALQ---LVSNQKQVILHVHPEQVVDVREKVAGVLS 154 L+A R++I VD + I +++ LQ L S + Q L VHP+ + V + + LS Sbjct: 125 LEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQ--LRVHPDDLQRVDDMLGATLS 182 Query: 155 DFPEVGYVDVVADARLKNGGCILETEVGIIDASIDGQIQAL 195 + + D L GGC + + G +DAS+ + Q L Sbjct: 183 ----LHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQEL 219
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 64.6 bits (157), Expect = 4e-14 Identities = 33/168 (19%), Positives = 73/168 (43%), Gaps = 8/168 (4%) Query: 22 TELYTNVSQKEGNEMLSILLSEGVVATKEPDKDNKVKLMVDSSQIAFAVDALKRKGYPRE 81 L++N+S ++G +++ L + + V + ++ L ++G P+ Sbjct: 51 RTLFSNLSDQDGGAIVAQLTQMNIPYRFANGSGA---IEVPADKVHELRLRLAQQGLPKG 107 Query: 82 QFSTLKEVFPKDDLISSPLAERARLVYAKSQELSSTLSQIDGVLVARVHVVL-EDQDLRP 140 + E+ ++ S +E+ A EL+ T+ + V ARVH+ + + Sbjct: 108 G-AVGFELLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVR 166 Query: 141 GERPTPASASVFIKHAADVALD-SYVPQIKLLVNNSIEGLNYDRISVV 187 ++ SASV + ALD + + LV++++ GL +++V Sbjct: 167 EQK--SPSASVTVTLEPGRALDEGQISAVVHLVSSAVAGLPPGNVTLV 212
>PF09025#YopR Core Length = 143 Score = 62.0 bits (150), Expect = 1e-14 Identities = 34/119 (28%), Positives = 47/119 (39%), Gaps = 1/119 (0%) Query: 89 PQTQKEALWYAFHQAKSAKGTDDAVPELLSVLKQELLGDFAGQLMAEPPTDRAALKAMLA 148 P + + + L + LL FA L DR LKAML Sbjct: 24 PAVDQVLAFEQALGGEPPAAGRRLAGLENGALGERLLQRFAQPLQG-LEADRLELKAMLR 82 Query: 149 QSFPLGAQKEQALWHCWAELKSLPEMTSTVDLVREELSFVIQKNAMVKNIMTHSHKLDL 207 PLG Q++ L ++ P L R EL +I N M+ N++ +SHKLDL Sbjct: 83 AELPLGRQQQTFLLQLLGAVEHAPGGEYLAQLARRELQVLIPLNGMLDNLVRNSHKLDL 141
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 577 bits (1489), Expect = 0.0 Identities = 288/594 (48%), Positives = 406/594 (68%), Gaps = 21/594 (3%) Query: 34 ATELNWPEQPFRYYADNDSLKDLLNNFGANYRVSVSVSDKVNDRVSGRFTPEDPAEFLDY 93 A EL+W P+ Y A +SL+DLL +FGANY +V VSDK+ND+VSG+F ++P +FL + Sbjct: 26 AQELDWLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKINDKVSGQFEHDNPQDFLQH 85 Query: 94 LAQVYNLMWYFDGAVLHVYKATETRSRLLQLELLTARELRSTLISTGVWDARYGWRAAEN 153 +A +YNL+WY+DG VL+++K +E SRL++L+ A EL+ L +G+W+ R+GWR + Sbjct: 86 IASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQALQRSGIWEPRFGWRPDAS 145 Query: 154 KGLVYLAGPPRYVELVVQTAEALESRLLQKSNSTDELFVELIPLKYASATDRSISYRDQS 213 LVY++GPPRY+ELV QTA ALE + +S T L +E+ PLKYASA+DR+I YRD Sbjct: 146 NRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEIFPLKYASASDRTIHYRDDE 205 Query: 214 ITVPGIASVLSRVVGGVQTQITDSASVQTSSVNGLPAEAAKPRGKTASVHGGATVEAEPG 273 + PG+A++L RV+ A++Q +V+ A R A VEA+P Sbjct: 206 VAAPGVATILQRVL--------SDATIQQVTVDNQRIPQAATRAS-----AQARVEADPS 252 Query: 274 LNAIIVRDTQARLPLYRKLVAQLDQPQSRIEVALSIVDISANDLRQLGVDWRAGVSVGNN 333 LNAIIVRD+ R+P+Y++L+ LD+P +RIEVALSIVDI+A+ L +LGVDWR G+ GNN Sbjct: 253 LNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINADQLTELGVDWRVGIRTGNN 312 Query: 334 RIVDIKTTGDVDNGDVTLGSGQSFKSLLDSTNLNYLLAQIRLLESKGSAQVVSRPTLLTQ 393 V IKTTGD N + S + SL+D+ L+YLLA++ LLE++GSAQVVSRPTLLTQ Sbjct: 313 HQVVIKTTGDQSN----IASNGALGSLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQ 368 Query: 394 ENVEAVLNNSSTFYVKLVGKETAALEEVTYGTLLRIVPRIVGDRFATRPEINLSLHLEDG 453 EN +AV+++S T+YVK+ GKE A L+ +TYGT+LR+ PR++ + EI+L+LH+EDG Sbjct: 369 ENAQAVIDHSETYYVKVTGKEVAELKGITYGTMLRMTPRVLTQ--GDKSEISLNLHIEDG 426 Query: 454 AKIPDG-GVDDLPSVRKTEISTLATVKQGQSLLIGGVYRDEVSHQLRKVPLLGDIPYLGA 512 + P+ G++ +P++ +T + T+A V GQSL+IGG+YRDE+S L KVPLLGDIPY+GA Sbjct: 427 NQKPNSSGIEGIPTISRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGA 486 Query: 513 LFRSNTNTTRRTVRMFIIEPRIVVDGIGDSVLIGNEHDLRPSIGQLNNISNNSAEFKSVV 572 LFR + TRRTVR+FIIEPRI+ +GI + +GN DLR I ++ ISN S ++ Sbjct: 487 LFRRKSELTRRTVRLFIIEPRIIDEGIAHHLALGNGQDLRTGILTVDEISNQSTTLNKLL 546 Query: 573 EVFSCTSKTQAERYQQDLLSQQKSSLLTQCQLPSGQVGWRVKVAECDLSQAECV 626 C +A+ Q+ L KSS LTQC++ +GWRV C +Q+ CV Sbjct: 547 GGSQCQPLNKAQEVQKWLSQNNKSSYLTQCKM-DKSLGWRVVEGACTPAQSWCV 599
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 39.0 bits (91), Expect = 1e-06 Identities = 15/124 (12%), Positives = 40/124 (32%), Gaps = 8/124 (6%) Query: 3 DKMMKSLAETLGIGPFIAGENGAYTIEVD-QLTLTIKQHSSWILWETALPLRFNEHLDYQ 61 ++ + +L + P + ++G + +D LT+ + L+ Sbjct: 7 KTLLDDFSRSLEMQPLVFDDHGTCNMIIDNTFALTLSCDYARERLLLIGL------LEPH 60 Query: 62 QEQALKRCMQLSLKTLRDTPSVLTTNADQQLILQGKAM-IENTSNDQFAELLAQHANVCE 120 ++ + + +L L + L + L +++ E S +A Sbjct: 61 KDIPQQCLLAGALNPLLNAGPGLGLDEKSGLYHAYQSIPREKLSVPTLKREMAGLLEWMR 120 Query: 121 RYME 124 + E Sbjct: 121 GWRE 124
>PilS_PF08805#PilS N terminal Length = 185 Score = 28.7 bits (64), Expect = 0.018 Identities = 13/67 (19%), Positives = 26/67 (38%), Gaps = 2/67 (2%) Query: 76 NVKTIAASMKRQDLTPKAARKFKCTTDSKHKMPVAPNLLAQDFNAAAPNQKWAGDITYVA 135 NV T+ A+MK + + + P+ + D A+ W G +T Sbjct: 66 NVLTVIANMKSLKFQ--GRYTDSNYIKTLYAQGLLPSDMIADTTGASAKNPWGGSVTITT 123 Query: 136 TSEGWLY 142 +S+ + + Sbjct: 124 SSDKYSF 130
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 2e-05 Identities = 20/79 (25%), Positives = 29/79 (36%), Gaps = 4/79 (5%) Query: 101 VDVSCRKQGIGQRLIDAVINFCQEKAEIDWLDLCVLSENFPAKNLYLKAGFDVVGEFKDQ 160 V RK+G+G L+ I + +E L L N A + Y K F + D Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKEN-HFCGLMLETQDINISACHFYAKHHFIIGA--VDT 153 Query: 161 YRIDGLSVS-ETAMTKYVK 178 + E A+ Y K Sbjct: 154 MLYSNFPTANEIAIFWYYK 172
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 30.7 bits (69), Expect = 0.003 Identities = 16/98 (16%), Positives = 27/98 (27%), Gaps = 14/98 (14%) Query: 15 LSFLIFTEPNNYKHYYERGILYGGEHIKSTECRESDYHGDYSQAIEDFDKVIELQPNFAN 74 L + + + + G G Y AI + + Sbjct: 59 FQALCVLDHYDSRFFLGLGACR---QAM----------GQYDLAIHSYSYGAIMDIKEPR 105 Query: 75 AYYHKACIYFDLGIDDDEAESLLEKALALEPNNSAYTI 112 +H A G + EAES L A L + + + Sbjct: 106 FPFHAAECLLQKG-ELAEAESGLFLAQELIADKTEFKE 142
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 36.1 bits (83), Expect = 2e-05 Identities = 12/62 (19%), Positives = 25/62 (40%), Gaps = 5/62 (8%) Query: 85 GYVLINYLIDSNGEIFNPTIVESSPKGEWDLIALKALSKVEYVPSESNSLNIPVYVTTEI 144 G V + + + +G + N I+ + P ++ A+ + Y P + S + I Sbjct: 178 GQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSG-----IVVNI 232 Query: 145 KF 146 F Sbjct: 233 LF 234
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 4e-04 Identities = 27/156 (17%), Positives = 57/156 (36%), Gaps = 37/156 (23%) Query: 4 LIPQWESKNLVFTEFSSDEAELAKSIFDSNLNVKAMDPTFREWSIIEYEKLIAESNKSKL 63 +IP +E+ +TE K D +++V ++ Sbjct: 26 MIPAFENGVWTYTEERF-SKPYFKQYEDDDMDVSYVE----------------------- 61 Query: 64 SDEQGAFYLRKISTKKGQVVGYIQMEFHAPSTGTLWLPMLTILPSFKGKGLGSEIVSSVI 123 +E A +L + +G I + + G + + + ++ KG+G ++++ Sbjct: 62 -EEGKAAFLYYLENN---CIGRI--KIRSNWNGYALIEDIAVAKDYRKKGVG----TALL 111 Query: 124 AVACEYA---NLQNVGLNVYAENISAFRFWYRQGFT 156 A E+A + + L NISA F+ + F Sbjct: 112 HKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 52.6 bits (126), Expect = 2e-11 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 5/112 (4%) Query: 17 WSTTEAML----LRDADSKENIGKYLKRNPNLSFVALDGDNIIGAILVGTD-GRRGYVQH 71 W+ TE + + + Y++ +F+ +N IG I + ++ ++ Sbjct: 35 WTYTEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIED 94 Query: 72 LAVDSTFRGKGVGAKLISSAVEALSKVGIAKTHLFVANENINAQSFYEKLGW 123 +AV +R KGVG L+ A+E + L + NI+A FY K + Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 41.1 bits (96), Expect = 4e-07 Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 5/79 (6%) Query: 74 FISFVDNKPAGFAVCFESFSTYRAQRVMNVHDFMVSDNFRGKGVGKAQLNGIEQYCRDND 133 F+ +++N G +++ Y + D V+ ++R KGVG A L+ ++ ++N Sbjct: 68 FLYYLENNCIGRIKIRSNWNGY-----ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122 Query: 134 YLKITLEVGDDNVAAKKLY 152 + + LE D N++A Y Sbjct: 123 FCGLMLETQDINISACHFY 141
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 45.4 bits (107), Expect = 2e-08 Identities = 43/182 (23%), Positives = 73/182 (40%), Gaps = 13/182 (7%) Query: 2 SNSALLVIDIQN---DYFPNGRFPLWNTDATLDNIKQLMARAKAQDIPI-FLVQHVSSAP 57 + + LL+ D+QN D F G P+ NI++L + IP+ + Q S P Sbjct: 29 NRAVLLIHDMQNYFVDAFTAGASPV---TELSANIRKLKNQCVQLGIPVVYTAQPGSQNP 85 Query: 58 KGKA---PFFEEGSVGVEIHPDIIS-ICPDAEIIQ--KQHADSFYQTDLEQALERNGVDE 111 +A F+ G II+ + P+ + + K +F +T+L + + + G D+ Sbjct: 86 DDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQ 145 Query: 112 LLICGMMTQNCVTHTAISKAAEKYNVSIIEDCCTTTDQMIHNIALSAVSIRVPLLASSDV 171 L+I G+ TA E + D H +AL + R +D Sbjct: 146 LIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMALEYAAGRCAFTVMTDS 205 Query: 172 LL 173 LL Sbjct: 206 LL 207
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 59.8 bits (145), Expect = 6e-12 Identities = 37/193 (19%), Positives = 76/193 (39%), Gaps = 14/193 (7%) Query: 40 GTIEKQAVAVGKIVPA-HSVSIKSQIDGIVGEIYAKVGEKVKQGQPLIKVRPNPTPQALT 98 G +E A A GK+ + S IK + IV EI K GE V++G L+K+ Sbjct: 78 GQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTA-------L 130 Query: 99 DASAELMRSEADLESAKQKLSNLESLVKQDIIPSNYDEYVSARSAVKSAQADVLQKRQNL 158 A A+ +++++ L A+ + + + L I N + + + Sbjct: 131 GAEADTLKTQSSLLQARLEQTRYQILS--RSIELNKLPELKLPDEPYFQNVSEEEVLRLT 188 Query: 159 ELIRSGEASIGDARLTSTIYAPIDGTVLNQKVEVGEPIISTQSSQAATEMMSLADMNSLI 218 LI+ ++ + + ++ + I+ + + E L D +SL+ Sbjct: 189 SLIKEQFSTWQNQKYQKE----LNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLL 244 Query: 219 FKGSVSEHDAAQL 231 K ++++H + Sbjct: 245 HKQAIAKHAVLEQ 257 Score = 49.1 bits (117), Expect = 2e-08 Identities = 27/153 (17%), Positives = 55/153 (35%), Gaps = 26/153 (16%) Query: 95 QALTDASAELMRSEADLESAKQKLSNLESLVKQDIIPSNYDEYVSARSAVKSAQADVLQK 154 L ++L + E+++ SAK++ + L K +I ++ ++ Sbjct: 266 NELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI-----------LDKLRQTTDNIGLL 314 Query: 155 RQNLELIRSGEASIGDARLTSTIYAPIDGTVLNQKV-EVGEPIISTQSSQAATEMMSLA- 212 L A + + S I AP+ V KV G + A +M + Sbjct: 315 TLEL-------AKNEERQQASVIRAPVSVKVQQLKVHTEGGVV------TTAETLMVIVP 361 Query: 213 DMNSLIFKGSVSEHDAAQLSPGMPVMLTVAPYP 245 + ++L V D ++ G ++ V +P Sbjct: 362 EDDTLEVTALVQNKDIGFINVGQNAIIKVEAFP 394
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.5 bits (79), Expect = 8e-05 Identities = 16/75 (21%), Positives = 34/75 (45%), Gaps = 4/75 (5%) Query: 74 ENQLVAFARLITDRTTFAYLADVFVVEAHRGKGISKWLISEIVAHPELQGLRRMMLATRD 133 EN + ++ ++ +A + D+ V + +R KG+ L+ + + + +ML T+D Sbjct: 73 ENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQD 132 Query: 134 ----AHGLYEQFGFT 144 A Y + F Sbjct: 133 INISACHFYAKHHFI 147
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 7e-21 Identities = 24/110 (21%), Positives = 45/110 (40%) Query: 10 VYVVDDDESVRDSLAFMLEEHDFNVTTFADGQSFLDEVNIHQAGCVILDSRMPNLRGQQV 69 + V DDD ++R L L ++V ++ + + V+ D MP+ + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 70 HQFLNEAHSPLAVIYLTGHGDVPMAVDALQAGAVNFFQKPVKGDELAQAI 119 + +A L V+ ++ A+ A + GA ++ KP EL I Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.032 Identities = 45/330 (13%), Positives = 102/330 (30%), Gaps = 71/330 (21%) Query: 253 PAIIAAGASGWTSPVSLLRIDKLYQALDLHPLQQPWWSEALRWLRSHQEWAWALFMFVIV 312 PA + G + + S+ R+ A AL + + + + + Sbjct: 82 PACVVIGMVWFVANTSIWRL----LAFINTKPVAFTLPLALSII-------FNVVVVTFM 130 Query: 313 LNAYHFGLEYRFSKSKQALELTSLRLKEKSEQLEHSQRVAIVGEIGSSLAHELNQPLAAI 372 + +FG + + + ++ + + QL + +I H + L I Sbjct: 131 WSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALK-----AQINP---HFMFNALNNI 182 Query: 373 RNYSEGGLLRLAKKRPHEDIVPVLEKIQGQVERADAIIQRLRTLIRKRSVDKTPCDIQAL 432 R I +A ++ L L+R S+ + +L Sbjct: 183 RAL-----------------------ILEDPTKAREMLTSLSELMRY-SLRYSNARQVSL 218 Query: 433 ------IADTIELLHFRMQKQNVAIVTSVEGEIRPLLADSVGVQQVLVNVINNAIDACAL 486 + ++L + + + + + I + + VQ ++ N I + I Sbjct: 219 ADELTVVDSYLQLASIQFEDR-LQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLP- 276 Query: 487 FQEKYHSSGYQGKIALHCDYQANQLSIRILDNGTGLQQENPTQAFVSSKAEGLGLGLAIC 546 GKI L +++ + + G+ + E G GL Sbjct: 277 ---------QGGKILLKGTKDNGTVTLEVENTGSLALKNTK---------ESTGTGLQNV 318 Query: 547 RDVME-MHGGEF-LIASTTPHGCLVELVFP 574 R+ ++ ++G E + S ++ P Sbjct: 319 RERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 522 bits (1346), Expect = 0.0 Identities = 198/335 (59%), Positives = 251/335 (74%), Gaps = 2/335 (0%) Query: 1 MKYLVTGAAGFIGSATIRKLNSLGYEVIGIDNINDYYDVELKYARLNFIKNPLFRFFNMD 60 MKYLVTGAAGFIG ++L G++V+GIDN+NDYYDV LK ARL + P F+F +D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 61 ISNKNKNEIERLFEKEKFDRVIHLAAQAGVRYSLVNPHCYAESNLSGFLNVLEACRKSHI 120 ++++ + LF F+RV + VRYSL NPH YA+SNL+GFLN+LE CR + I Sbjct: 61 LADREG--MTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 121 KHFIYASSSSVYGLNKKVPFSTSDNVDHPVSLYAATKKSNELMAHSYSHLYQLPTTGLRF 180 +H +YASSSSVYGLN+K+PFST D+VDHPVSLYAATKK+NELMAH+YSHLY LP TGLRF Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRF 178 Query: 181 FTVYGSWGRPDMAPFIFTEKIINGQSIDINNNGDMWRDFTHINDIVEGIVRISDVIPRIN 240 FTVYG WGRPDMA F FT+ ++ G+SID+ N G M RDFT+I+DI E I+R+ DVIP + Sbjct: 179 FTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHAD 238 Query: 241 QRWQFENSTPADSSAPYSIYNIGYGSPICLMDFIKAIENELGIEAKKNYREMQPGDVYQT 300 +W E TPA S APY +YNIG SP+ LMD+I+A+E+ LGIEAKKN +QPGDV +T Sbjct: 239 TQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVLET 298 Query: 301 YADTTAFYQATGYRPSVSVEEGIAEFVAWYRNFYN 335 ADT A Y+ G+ P +V++G+ FV WYR+FY Sbjct: 299 SADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYK 333
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 28.0 bits (62), Expect = 0.044 Identities = 19/90 (21%), Positives = 26/90 (28%), Gaps = 11/90 (12%) Query: 196 GNSNKAIQHFKKALSEDPKCVRASISLGRIYLESEDYKQTIK-YLTGVLEQDKDFVSDVL 254 G A + F+ D R + LG Y I Y G + K+ Sbjct: 50 GKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKE------ 103 Query: 255 PT----IAECYHHLGQEDELVEFLRACIDK 280 P AEC G+ E L + Sbjct: 104 PRFPFHAAECLLQKGELAEAESGLFLAQEL 133
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 119 bits (301), Expect = 2e-39 Identities = 33/89 (37%), Positives = 57/89 (64%), Gaps = 1/89 (1%) Query: 2 TKSELIERLCAEQTHLSAKEVEDAVKDILEHMASTLESGDRIEIRGFGSFSLHYREPRVG 61 K +LI ++ AE T L+ K+ AV + ++S L G+++++ GFG+F + R R G Sbjct: 3 NKQDLIAKV-AEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 62 RNPKTGDKVELEGKYVPHFKPGKELRERV 90 RNP+TG++++++ VP FK GK L++ V Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 29.3 bits (65), Expect = 0.044 Identities = 17/104 (16%), Positives = 43/104 (41%), Gaps = 7/104 (6%) Query: 320 ERRTKQRKEMDQQAKLPKSQRKNNLNNYLLKRQAIQRKELASDIEAGRSELDDIKTQVAI 379 + +T + ++ +A+ + ++ + + K L ++ A +E D++ Q + Sbjct: 247 KIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQV 306 Query: 380 STGENEMINELKRQNSRDISAEKKEIVQLRAEKHALEKLVQSLK 423 + + RD+ A ++ QL AE LE+ + + Sbjct: 307 LNANRQSL-------RRDLDASREAKKQLEAEHQKLEEQNKISE 343
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.0 bits (85), Expect = 9e-05 Identities = 31/188 (16%), Positives = 63/188 (33%), Gaps = 7/188 (3%) Query: 121 RIREAEAISQHAIKQKEQSEGEALDIEQTLQRATDANDQLEEKIEALQSEVVESQIEKSE 180 A + +K D+E+ L+ A + + KI+ L++E + ++E Sbjct: 135 FSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAE 194 Query: 181 LLKNISQLTSSLNQTNDRLENQQDTICGLQASLSKVEKMNSALTVQLEHALNDAKKLESQ 240 L K + + + +++ + L A + +EK K LE++ Sbjct: 195 LEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAE 254 Query: 241 LTELSERYESTCIKLTESSSKLQSMTEALDNSEHKLSTVQDEYTDLSVNYRILESKLHES 300 L + E L+ K+ T++ E L LE + Sbjct: 255 KAALEA-------RQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVL 307 Query: 301 QSNISELK 308 +N L+ Sbjct: 308 NANRQSLR 315 Score = 33.9 bits (77), Expect = 8e-04 Identities = 32/192 (16%), Positives = 77/192 (40%), Gaps = 7/192 (3%) Query: 134 KQKEQSEGEALDIEQTLQRATDANDQLEEKIEALQSEVVESQIEKSELLKNISQLTSSLN 193 +K D+E+ L+ A + + KI+ L++E + ++EL K + + Sbjct: 218 AEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFST 277 Query: 194 QTNDRLENQQDTICGLQASLSKVEKMNSALTV-------QLEHALNDAKKLESQLTELSE 246 + +++ + L+A + +E + L L+ + K+LE++ +L E Sbjct: 278 ADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEE 337 Query: 247 RYESTCIKLTESSSKLQSMTEALDNSEHKLSTVQDEYTDLSVNYRILESKLHESQSNISE 306 + + + L + EA E + ++++ + + L L S+ + Sbjct: 338 QNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ 397 Query: 307 LKLANHELEKQL 318 ++ A E +L Sbjct: 398 VEKALEEANSKL 409
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 37.7 bits (87), Expect = 2e-04 Identities = 32/149 (21%), Positives = 68/149 (45%), Gaps = 25/149 (16%) Query: 320 AKAEEKKIQQKLQEQKAQIAAKEQEITQIIENVALKRREAQ---DEIKRIAAETEDEVRQ 376 A A +Q + +++ ++A E++ + E +EA+ EI+R AETE +++ Sbjct: 116 AHANNAAMQAE--DERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKL 173 Query: 377 TLKLKQQELSENIAALEDEQNSLE--KQIIDKVQHLELVNEIEKLKEECNYYEKHSKRLE 434 +++ AAL +E ++E ++ + Q +E+ K+ E + RL Sbjct: 174 AEAEEKRL-----AALSEEAKAVEIAQKKLSAAQ-----SEVVKMDGEIK---TLNSRLS 220 Query: 435 STVKGFEATLKNNDTEELAKKIGEMEAIN 463 S++ +A + + LA K E+ + Sbjct: 221 SSIHARDA-----EMKTLAGKRNELAQAS 244
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 367 bits (945), Expect = e-129 Identities = 114/354 (32%), Positives = 190/354 (53%), Gaps = 14/354 (3%) Query: 8 ERTEEATPRRLQQAREKGQVARSKELASASVLIVGAIALMWFGESLARSLFSIMSRLFDL 67 E+TE+ TP++++ AR+KGQVA+SKE+ S ++++ + LM L+ F S+L + Sbjct: 4 EKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLM----GLSDYYFEHFSKLMLI 59 Query: 68 KRDEIFDTTKLFDIALGAMTDLLFPLFLI--LITLFVAATIGAAG---VGGISFSAEAAM 122 ++ + F AL + D + F L VAA + A G S EA Sbjct: 60 PAEQSYLP---FSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIK 116 Query: 123 PKLSKMNPLSGLKRMVGMQSWVELIKSILKVVLVTGVAMYLIQASQADLIQLSMDVYPQN 182 P + K+NP+ G KR+ ++S VE +KSILKVVL++ + +I+ + L+QL + Sbjct: 117 PDIKKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQL-PTCGIEC 175 Query: 183 IFHAL-DILLNFILLISCSLLIVVAIDIPFQIWQHADQLKMTKQEVKDEYKETEGKPEVK 241 I L IL +++ + +++ D F+ +Q+ +LKM+K E+K EYKE EG PE+K Sbjct: 176 ITPLLGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIK 235 Query: 242 GRIRMLQREAAQRRMMADVPQADVIVTNPEHYSVALRYKQKTDRAPVVIAKGTDHMAMKI 301 + R +E R M +V ++ V+V NP H ++ + YK+ P+V K TD + Sbjct: 236 SKRRQFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTV 295 Query: 302 REVAREHDITIVPAPPLARALYHTTELEQEIPDGLFTAVAQVLAFVFQLKQYRK 355 R++A E + I+ PLARALY ++ IP A A+VL ++ + ++ Sbjct: 296 RKIAEEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEKQ 349
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 121 bits (306), Expect = 1e-35 Identities = 81/221 (36%), Positives = 129/221 (58%), Gaps = 2/221 (0%) Query: 9 LDWIANYFWPYVRISSMLMVMTVTGARFVSPRIRLYLGLAITFAVMPAIPAVPQDIQLLS 68 L W+ YFWP +R+ +++ + R V R++L L + ITFA+ P++PA D+ + S Sbjct: 10 LSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA--NDVPVFS 67 Query: 69 FRGFMTIAEQMIIGVAMGMVTQFMIQTFVLLGQILGMQSSLGFASMVDPANGQNTPLLGQ 128 F +Q++IG+A+G QF G+I+G+Q L FA+ VDPA+ N P+L + Sbjct: 68 FFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLAR 127 Query: 129 LFMFLTTMFFLATDGHLKMLQLVVFSFKTLPIGSGTLTAVDFRDMAGWLGIMFKTALSMS 188 + L + FL +GHL ++ L+V +F TLPIG L + F + ++F L ++ Sbjct: 128 IMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLA 187 Query: 189 LSGIIALLTINLSFGVMTRAAPQLNIFSLGFAFALMVGLLI 229 L I LLT+NL+ G++ R APQL+IF +GF L VG+ + Sbjct: 188 LPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISL 228
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 54.8 bits (132), Expect = 8e-14 Identities = 26/70 (37%), Positives = 40/70 (57%) Query: 7 VELFREALWMVLIMVCAIIIPSLLIGLVVAIFQAATSINEQTLSFLPRLIVTLLALMLFG 66 V +AL++VLI+ I + +IGL+V +FQ T + EQTL F +L+ L L L Sbjct: 5 VFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLLS 64 Query: 67 HWMTQMLMEY 76 W ++L+ Y Sbjct: 65 GWYGEVLLSY 74
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 285 bits (732), Expect = 2e-99 Identities = 116/229 (50%), Positives = 166/229 (72%), Gaps = 1/229 (0%) Query: 60 MSVGNGAGIPAFTMTTNPDGSEDYSVTLQILALMTMLGFLPAMVILMTSFTRIVVVMSIL 119 ++ A +P T P G + +S+ +Q L +T L F+PA++++MTSFTRI++V +L Sbjct: 15 ITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTSFTRIIIVFGLL 74 Query: 120 RQAMGLQQTPSNQVIIGIALFLTFFVMSPVLNEINDTAIQPYLNEQVTAREAFDAAQVPM 179 R A+G P NQV++G+ALFLTFF+MSPV+++I A QP+ E+++ +EA + P+ Sbjct: 75 RNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQEALEKGAQPL 134 Query: 180 KAFMLKQTRIKDLETFVNMSGE-QVTNPEDVSMAVLIPAFITSELKTAFQIGFMLFLPFL 238 + FML+QTR DL F ++ + PE V M +L+PA++TSELKTAFQIGF +F+PFL Sbjct: 135 REFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFL 194 Query: 239 IIDLVVASVLMAMGMMMLSPMIVSLPFKLMLFVLVDGWNLILSTLAGSF 287 IIDLV+ASVLMA+GMMM+ P ++LPFKLMLFVLVDGW L++ +LA SF Sbjct: 195 IIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQSF 243
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 113 bits (285), Expect = 1e-35 Identities = 63/135 (46%), Positives = 91/135 (67%), Gaps = 8/135 (5%) Query: 3 PSDDQK--LADEWAAALGEDPSAPSIDVDEVLAAPLEELKDTSRPITDDERRKLDTIMDI 60 PSD+ L D WA AL E + + + + L D S + D +D IMDI Sbjct: 7 PSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGG-GDVSGAMQD-----IDLIMDI 60 Query: 61 PVTISMEVGRSQISIRNLLQLNQGSVVELDRLAGESLDVLVNGTLIAHGEVVVVNDKFGI 120 PV +++E+GR++++I+ LL+L QGSVV LD LAGE LD+L+NG LIA GEVVVV DK+G+ Sbjct: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 Query: 121 RLTDVISQTERIKKL 135 R+TD+I+ +ER+++L Sbjct: 121 RITDIITPSERMRRL 135
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 241 bits (617), Expect = 8e-80 Identities = 86/327 (26%), Positives = 163/327 (49%), Gaps = 9/327 (2%) Query: 1 MTDLLSQDEIDALLHGVD--DVDDIDEPLDNDTEGAVSFDFSSQDRIVRGRMPTLELINE 58 MT++LSQDEID LL + D D +DT +DF D+ + +M TL L++E Sbjct: 1 MTEVLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHE 60 Query: 59 RFARHMRISLFNMLRKTAEVSINGVQMMKFGEYQNTLYVPTSLNMVRFRPLKGTALITME 118 FAR SL LR V + V + + E+ ++ P++L ++ PLKG A++ ++ Sbjct: 61 TFARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVD 120 Query: 119 ARLVFILVENFFGGDGRFHAKIEGREFTPTERRIIQLLLKIVFEDYKEAWSPVMGVEFEY 178 + F +++ FGG G+ R+ T E +++ ++ + + +E+W+ V+ + Sbjct: 121 PSITFSIIDRLFGGTGQAAKVQ--RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRL 178 Query: 179 LDSEVNPSMANIVSPTEVIVVSSFHIEVDGGGGDFHVVMPYSMVEPIRELLDAG--VQSD 236 E NP A IV P+E++V+ + +V G + +PY +EPI L + S Sbjct: 179 GQIETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSV 238 Query: 237 KMETDVRWSSALREEIMDCPVNFRVNLLEKDISLRDLMELQPGDIIPIE---MPEHATMF 293 + + ++ LR+++ ++ + +S+RD++ L+ GDII + + + + Sbjct: 239 RRSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLS 298 Query: 294 IEDLPTYRVKMGRSEDKLAVQVSQEIE 320 I + + + G K+A Q+ + IE Sbjct: 299 IGNRKKFLCQPGVVGKKIAAQILERIE 325
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 47.5 bits (112), Expect = 9e-08 Identities = 28/120 (23%), Positives = 63/120 (52%) Query: 509 EQVAEKVQMMMSKNLKNLDIRLDPPELGRMQIRMTMNNDLANVHFTVTNPQARDIIEQTL 568 + +++ + + + ++ ++RL P +LG +QI + ++++ A + + R +E L Sbjct: 242 QSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAAL 301 Query: 569 PRLREMLAQQGMQLADSSVQQQSSGQQQSGYAAAEQNGQGTSGRGFSGQSDENFDADVNL 628 P LR LA+ G+QL S++ +S QQ + +Q+ + + +G+ D+ V+L Sbjct: 302 PVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVSL 361
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 38.3 bits (88), Expect = 3e-06 Identities = 29/142 (20%), Positives = 76/142 (53%) Query: 2 NNAMEFLLEQTKEREDQAVLALNKARSELEDYYRQVEQIEKYRLDYCQQLVDRGQAGLTA 61 + A+ L + ++ + A L + R + Q++ + Y+ +Y L AG+T+ Sbjct: 4 HGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAGITS 63 Query: 62 SQYGHLNRFLCQLDETLSKQKQAEHHFKEQVENCKDYWLKMRQERMSYEWMIEKKAKEKQ 121 +++ + +F+ L++ +++ +Q + + ++V+ + W + +Q +++ + E+++ Sbjct: 64 NRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQSTAAL 123 Query: 122 IAEAKREQKQMDEFSTLLFSRK 143 +AE + +QK+MDEF+ RK Sbjct: 124 LAENRLDQKKMDEFAQRAAMRK 145
>DPTHRIATOXIN#Diphtheria toxin signature. Length = 567 Score = 30.1 bits (67), Expect = 0.015 Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 10/72 (13%) Query: 249 VERTFSQNISTYDECWQVIEEKLYPELEKRLERA--------SPDKSIIKQGIKVKFADF 300 V R+ ++S + W VI +K ++E E SP+K++ ++ K +F Sbjct: 223 VRRSVGSSLSCINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEF 282 Query: 301 QLTTIEHIHPQL 312 T +E HP+L Sbjct: 283 HQTALE--HPEL 292
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 182 bits (463), Expect = 5e-57 Identities = 82/345 (23%), Positives = 142/345 (41%), Gaps = 35/345 (10%) Query: 1 MKVLVTGGMGYIGSHTCVQMIEAGIEPIIVDNLCNAKLEVLN--RIEALTGKQPAFHQGD 58 MK LVTG G+IG H +++EAG + + +DNL + L R+E L FH+ D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 59 IRDEAFLDTVFAQHDIQAVIHFAGLKAVGESVAKPLEYYDNNVNGSLVLARSMRKSGVKS 118 + D + +FA + V AV S+ P Y D+N+ G L + R + ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 119 IVFSSSATVYGDPEIVPITEDSPTGATTNPYGRSKYMVEQCFSDLFHAENDWSITLLRYF 178 ++++SS++VYG +P + D + Y +K E + + T LR+F Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE-LMAHTYSHLYGLPATGLRFF 179 Query: 179 NPVGAHSSGSMGEDPQGIPNNLMPFIAQVAVGRREKLAVFGSDYPTPDGTGVRDYIHVMD 238 G P G P ++ F A+ + + V+ G RD+ ++ D Sbjct: 180 TVYG----------PWGRP-DMALFKFTKAMLEGKSIDVYN------YGKMKRDFTYIDD 222 Query: 239 LADGHIAALKSVGKTSG---------------LHIYNLGTGKGSSVLEMVDAFAAACGKP 283 +A+ I + +YN+G +++ + A A G Sbjct: 223 IAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIE 282 Query: 284 VPYELCPRRPGDIAECWASTEKAERELGWKATRTVAEMTADTWNW 328 + P +PGD+ E A T+ +G+ TV + + NW Sbjct: 283 AKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNW 327
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 77.6 bits (191), Expect = 1e-16 Identities = 71/313 (22%), Positives = 112/313 (35%), Gaps = 77/313 (24%) Query: 411 IMGHVDHGKTSTLDYIRRTHVASGEAG------------------GITQHIGAYHVETEN 452 ++ HVD GKT+ + + A E G GIT G + EN Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 453 GMITFLDTPGHAAFTAMRARGAQATDIVVLVVAADDGVMPQTVEAIQHAKAAGVPLIVAV 512 + +DTPGH F A R D +L+++A DGV QT + G+P I + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 513 NKIDKEDANPD----NVKNELAQYDVI-----------------PEEWG----------- 540 NKID+ + ++K +L+ VI E+W Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 541 ---------------GENMFV---------HISAKQGTNIDGLLEAILLQSEVLELTAVK 576 E++ H SAK ID L+E I ++ T Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 577 EGMASGVVVESRLDKGRGPVATVLVQSGTLHKGDIVL-CGQEYGRVRAMRDELGQEITEA 635 + G V + + R +A + + SG LH D V +E ++ M + E+ + Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKI 305 Query: 636 GPSIPVEILGLSG 648 + EI+ L Sbjct: 306 DKAYSGEIVILQN 318
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 64.6 bits (157), Expect = 4e-15 Identities = 28/208 (13%), Positives = 71/208 (34%), Gaps = 20/208 (9%) Query: 4 IAKRPRTRLSPLKRKQQLMEIALEVFARRGIGRGGHADIAEIAQVSVATVFNYFPTREDL 63 +A++ + +Q ++++AL +F+++G+ +IA+ A V+ ++ +F + DL Sbjct: 1 MARKTKQEAQE--TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDL 58 Query: 64 VDEVLNHVVRQFSNFLSDNIDLDIHARENIANITNAMIELVSQDCH------WLKVWFEW 117 E+ + + ++ + +I ++ +++ F Sbjct: 59 FSEIWELSESNIGELELEYQAKF--PGDPLSVLREILIHVLESTVTEERRRLLMEIIFHK 116 Query: 118 SASTRDEVWPLFVSTNRTNQLLVQNMFI----KAIERGEVCDQHDSEHLANLFHGICYSL 173 + + R L + IE + + A + G L Sbjct: 117 CEFVGE--MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174 Query: 174 FVQANRFKGEAELKE----LVSAYLDML 197 +LK+ V+ L+M Sbjct: 175 MENWLFAPQSFDLKKEARDYVAILLEMY 202
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.3 bits (89), Expect = 8e-05 Identities = 41/281 (14%), Positives = 90/281 (32%), Gaps = 35/281 (12%) Query: 26 DKVEEEQSLITVEGDKASMEVPASQAGIVKEIKVAEGDKVSTGSLIMIFE---AEGAADA 82 + V +T G S E+ + IVKEI V EG+ V G +++ AE Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 83 APAPAAEAAPAAAPAPAAAAELKEVHVPDIG------------GDEVEVTEIMVAIGDSI 130 + +A + ++ +P++ + + +T ++ + Sbjct: 139 TQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTW 198 Query: 131 EEEQSLITVEGDKASMEVPAPFAGTLKEIKVAAGDKVSTGSLIMVFETAGSGAPAAPAAV 190 + ++ + DK E A + ++ +K + + A A Sbjct: 199 QNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH-KQAIAKHAVLEQ 257 Query: 191 EAPAAAAPAASAAKEVNVPDIGGDEVEV----------------TEIMVAVGDTVEEEQS 234 E A + + I + + ++ + Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE 317 Query: 235 LITVEGDKASMEVPAPFAGTVKEIKIAA-GDKVSTGSLIMV 274 L E + + + AP + V+++K+ G V+T +MV Sbjct: 318 LAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 567 bits (1463), Expect = 0.0 Identities = 318/347 (91%), Positives = 334/347 (96%) Query: 1 MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRVGSAKSVAAVGHAAK 60 M KK RGMFSNDLSIDLGTANTLIYVKGQGIVL+EPSVVAIRQDR GS KSVAAVGH AK Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK 60 Query: 61 QMLGRTPGNISAIRPMKDGVIADFYVTEKMLQHFIKQVHDNSILKPSPRVLVCVPCGSTQ 120 QMLGRTPGNI+AIRPMKDGVIADF+VTEKMLQHFIKQVH NS ++PSPRVLVCVP G+TQ Sbjct: 61 QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ 120 Query: 121 VERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTGSMVVDIGGGTTEVAVISLNG 180 VERRAIRESA GAGAREV+LI+EPMAAAIGAGL VSE TGSMVVDIGGGTTEVAVISLNG Sbjct: 121 VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG 180 Query: 181 VVYSSSVRIGGDRFDEAVINYVRRNYGSLIGEATAEKIKHEIGSAYPGDEVQEIEVRGRN 240 VVYSSSVRIGGDRFDEA+INYVRRNYGSLIGEATAE+IKHEIGSAYPGDEV+EIEVRGRN Sbjct: 181 VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN 240 Query: 241 LAEGVPRSFSLNSNEILEALQEPLSGIVSAVMVALEQCPPELASDISENGMVLTGGGALL 300 LAEGVPR F+LNSNEILEALQEPL+GIVSAVMVALEQCPPELASDISE GMVLTGGGALL Sbjct: 241 LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL 300 Query: 301 KDLDRLLMEETGIPVVIAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347 ++LDRLLMEETGIPVV+AEDPLTCVARGGGKALEMIDMHGGDLFSEE Sbjct: 301 RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.2 bits (73), Expect = 8e-04 Identities = 17/50 (34%), Positives = 27/50 (54%), Gaps = 6/50 (12%) Query: 2 KTRGFTLMEMIVTIVIGSFIMLGI-AGYVQLGMKGYADTIDRQRMQTQAQ 50 K RGFTL+E++V IVI +G+ A V + G + D+Q+ + Sbjct: 6 KQRGFTLLEIMVVIVI-----IGVLASLVVPNLMGNKEKADKQKAVSDIV 50
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.1 bits (239), Expect = 3e-25 Identities = 39/125 (31%), Positives = 63/125 (50%), Gaps = 2/125 (1%) Query: 2 ANILLIDDDIELTSLLKEVLSFEGFEVSEANDGEAGLAAINSD-IDLILLDVMMPKLNGM 60 A IL+ DDD + ++L + LS G++V ++ I + DL++ DV+MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 61 ETLKRLRENWE-TPVLMLTAKGEEIDRVIGLELGADDYLPKPFSDRELLARIRAILRRTS 119 + L R+++ PVL+++A+ + + E GA DYLPKPF EL+ I L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 120 NTQKN 124 Sbjct: 124 RRPSK 128
>PF06580#Sensor histidine kinase Length = 349 Score = 42.2 bits (99), Expect = 3e-06 Identities = 29/189 (15%), Positives = 63/189 (33%), Gaps = 40/189 (21%) Query: 287 IDTEAQRLEQMISELLELSRMQVNSHMTRETQPIESLWEEI-IKDAQFEAEQMGKTLRYS 345 I + + +M++ L EL R + SL +E+ + D+ + + ++ Sbjct: 186 ILEDPTKAREMLTSLSELMRYS----LRYSNARQVSLADELTVVDSYLQLASI----QFE 237 Query: 346 EIPERHISGNPKLLMSAVEN-----IIRNAIYYG------KDEVQIDIQDKTDTLTITVD 394 + + NP ++ V ++ N I +G ++ + T+T+ V+ Sbjct: 238 DRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVE 297 Query: 395 DNGDGVPDEELEAIFRPFYRVSTARDRHSGGTGLGLTITESAIRQHSGTI--VASRSPLG 452 + G E TG GL ++ GT + G Sbjct: 298 NTGSLALKNTKE------------------STGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 453 GLRVSITLP 461 + + +P Sbjct: 340 KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.4 bits (201), Expect = 3e-20 Identities = 41/169 (24%), Positives = 76/169 (44%), Gaps = 16/169 (9%) Query: 1 MDSTYTIIIADDHPLFRNALFQSVHMAVSGANLLEADSLDALLALLAKEEEPDLVLLDLK 60 M TI++ADD R L + ++ +G ++ + L +A + DLV+ D+ Sbjct: 1 MTGA-TILVADDDAAIRTVL--NQALSRAGYDVRITSNAATLWRWIA-AGDGDLVVTDVV 56 Query: 61 MPGANGMSGLIHLRAEYPDLPIVVVSA-SEEPTVVSQVKSHGAFGFIPKSSDMRELVNAL 119 MP N L ++ PDLP++V+SA + T + + GA+ ++PK D+ EL+ + Sbjct: 57 MPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEK-GAYDYLPKPFDLTELIGII 115 Query: 120 NQVL----------NGDPYFPEGLITNNAACNDLAEKIAALTPQQYKVL 158 + L D L+ +AA ++ +A L ++ Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLM 164
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.1 bits (169), Expect = 5e-14 Identities = 20/116 (17%), Positives = 50/116 (43%), Gaps = 4/116 (3%) Query: 1027 RILCVDNEPDILVGMENLLSRWGCDIRVATDLIESLQALEGDWVPDVIFSDYRLDNGRTG 1086 IL D++ I + LSR G D+R+ ++ + + D++ +D + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMP-DENA 62 Query: 1087 LEVLQQCRLRLGNHFEGVIISADRT-DDMMEGIKANGFSFIAKPVKPLKLRSVLNR 1141 ++L + + + +++SA T ++ + + ++ KP +L ++ R Sbjct: 63 FDLLPRIK-KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.7 bits (92), Expect = 2e-05 Identities = 30/130 (23%), Positives = 49/130 (37%), Gaps = 29/130 (22%) Query: 18 EEQSPKPKTEETVTEEAVEAPSE--------------EQQTEEVAEQAQQTQELEQEPEK 63 E + KT E ++A E ++ QT EVA+ +T+E Q E Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKE-TQTTET 1100 Query: 64 AEAAPAEAEAEAEAEAE--AEEPQV------------PVAPRIQEQEKPTESFFARLKRS 109 E A E E +A+ E E E P+V V P+ + + + + +S Sbjct: 1101 KETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQS 1160 Query: 110 LSRTKANIGA 119 + T A+ Sbjct: 1161 QTNTTADTEQ 1170 Score = 34.3 bits (78), Expect = 0.001 Identities = 20/82 (24%), Positives = 30/82 (36%), Gaps = 7/82 (8%) Query: 17 DEEQSPKPKTEETVTEEAVEAP----SEEQQTEEVAEQAQQTQELEQEPEKAEAAPAEAE 72 D P E +EA P + + TE VAE ++Q + EK E E Sbjct: 1006 DVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQE---SKTVEKNEQDATETT 1062 Query: 73 AEAEAEAEAEEPQVPVAPRIQE 94 A+ A+ + V + E Sbjct: 1063 AQNREVAKEAKSNVKANTQTNE 1084 Score = 30.8 bits (69), Expect = 0.011 Identities = 16/85 (18%), Positives = 29/85 (34%), Gaps = 1/85 (1%) Query: 17 DEEQSPKPKTEETVTEEAVEAPSEEQQTEEVAEQAQQTQELEQEPEKAEAAP-AEAEAEA 75 E+ K K E T+E + S+ +E +E Q E +E + +++ Sbjct: 1105 TVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNT 1164 Query: 76 EAEAEAEEPQVPVAPRIQEQEKPTE 100 A+ E + E T Sbjct: 1165 TADTEQPAKETSSNVEQPVTESTTV 1189
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 25.9 bits (57), Expect = 0.023 Identities = 10/33 (30%), Positives = 14/33 (42%), Gaps = 1/33 (3%) Query: 3 ALLILAKAAIAFVWLVLI-LNIVMPFPGNAAVA 34 A I+ IAF+ VL + IV G + Sbjct: 61 AYFIMGFLVIAFILSVLGQVEIVATANGKLTHS 93
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 28.2 bits (62), Expect = 0.005 Identities = 18/76 (23%), Positives = 34/76 (44%), Gaps = 13/76 (17%) Query: 39 LEFEDRSQIIINRQEPMHEIWLASKSGGFHFKLVEDKWTCSKTGME----------LFEM 88 L+ + +S ++ N QEP L + GG+ FK K+ G++ L ++ Sbjct: 165 LKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDL 224 Query: 89 VKQECEKHAGEEIDWA 104 +K KH + D++ Sbjct: 225 IKN---KHMNADTDYS 237
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.020 Identities = 8/67 (11%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 90 QQADYQAQIAQLQNQLEKAQASMKQELNQVKEETIEKATTVTHKAEVVLGQQQKSIESLQ 149 + Y++Q+ Q+++++ A+ + K E ++K T ++ + + + Sbjct: 267 ELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLL--TLELAKNEER 324 Query: 150 LAVADVK 156 + ++ Sbjct: 325 QQASVIR 331
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.8 bits (69), Expect = 0.012 Identities = 14/99 (14%), Positives = 30/99 (30%), Gaps = 8/99 (8%) Query: 49 IATLAGLFLLEYLIKKLVYASSST--WNYFSVRKM------RRSRRYTNEGIIKLLEGDW 100 I ++ + L ++K + ++ Y R + N+ + +L + W Sbjct: 672 IKEVSNIKDLSSNVEKSQFFTTYDMRGTYVGGRSQGEENDWKDMNSKLNDILKELSKKSW 731 Query: 101 KGAEKKVTRWANHHDMPLLCYLVASEAAQGQGDKAKRDH 139 G + + NH Y+ D H Sbjct: 732 NGYKTVTAYFVNHKVDGNGNYVYDVVFHGMNTDTNTDVH 770
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 31.3 bits (71), Expect = 0.004 Identities = 16/120 (13%), Positives = 42/120 (35%), Gaps = 3/120 (2%) Query: 147 LIVFGSVPIVAMALAMSFGFYGLLRKKVAVDAQTGLFVETLILLPAAAVYLLFIASSPTA 206 L + +VA A + + ++ D + +I + A ++++ T Sbjct: 124 LAILQGTGLVATARSAPLFGRCSVGGQIVPDQSIFTTITMVICMTAGTCVVMWLGELITD 183 Query: 207 NMIENPWQLNTLLIAAGVVTTLPLLCFTGAATRLKLSTLGFFQYIGPSLMFLLAVLIYGE 266 I N ++L+ + T P + F + + ++A++++ E Sbjct: 184 RGIGNG---MSILMFISIAATFPSALWAIKKQGTLAGGWIEFGTVIAVGLIMVALVVFVE 240
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.8 bits (67), Expect = 0.022 Identities = 16/82 (19%), Positives = 34/82 (41%), Gaps = 12/82 (14%) Query: 1 MKIIILG-AGQVGGTLAENLVGENNDITIVDNNADRLRELQDKYDLRVVNGHA---SHPD 56 MK ++ G AG +G +++ L+ + + +DN L D YD+ + + P Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDN-------LNDYYDVSLKQARLELLAQPG 53 Query: 57 V-LHEAGAQDADMLVAVTNTDE 77 H+ D + + + + Sbjct: 54 FQFHKIDLADREGMTDLFASGH 75
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 220 bits (561), Expect = 6e-73 Identities = 78/281 (27%), Positives = 134/281 (47%), Gaps = 29/281 (10%) Query: 30 LSLLLTCLFIAITGWILGKVVW-LAIPQTSDVPKWRPSAGNVIASNKSNTIDFNALQSAN 88 + +L L + + L + W + +P + P A + T L Sbjct: 14 IRRILFYLLMLLFCQQLAMIFWRIGLPDNA--PVSSVQITPAQARQQPVT-----LNDFT 66 Query: 89 LFGKYTEQK-PVVVEQPVVKDAPKTRLNLTLVGAVASSNPQTSLAVIANRGKQATYGISE 147 LFG E+ ++ + + P + LNL+L G +A + S+A+I+ +Q + G++E Sbjct: 67 LFGVSPEKNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRGVNE 126 Query: 148 EIEGTRATLKAVLVDRVIIDNEGRDETLMLEGVEYKKLSESPQATRVQAAQKEPASDVSD 207 E+ G A + ++ DRV++ +GR E L L E P A Sbjct: 127 EVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVPGA---------------- 170 Query: 208 KLEQIREEI-AKDPQSVFKYITISPVKKDDAIIGYRVSPGRDAALFNDVGLEPGDIAVQL 266 Q+ E++ + ++ Y++ SP+ D+ + GYR++PG + F VGL+ D+AV L Sbjct: 171 ---QVNEQLQQRASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVAL 227 Query: 267 NGIDLSDPSSSVQLMQVMSDPQELNLTVERDGQQYDIYIQL 307 NG+DL D + + M+ M+D LTVERDGQ+ DIY++ Sbjct: 228 NGLDLRDAEQAKKAMERMADVHNFTLTVERDGQRQDIYMEF 268
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 641 bits (1655), Expect = 0.0 Identities = 325/665 (48%), Positives = 453/665 (68%), Gaps = 32/665 (4%) Query: 11 LLAGSLLCVPGAMANEFSASFKGTDIQEFINIVGRNLEKTIIVDPSVRGKIDVRSYDVLN 70 L+ +LL P A A EFSASFKGTDIQEFIN V +NL KT+I+DPSVRG I VRSYD+LN Sbjct: 15 LIFAALLFRP-AAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLN 73 Query: 71 EEQYYSFFLNVLEVYGYAVVEMDNGVLKVIKAKDSKTSAIPVMGDGS-AKGDSVITRVVA 129 EEQYY FFL+VL+VYG+AV+ M+NGVLKV+++KD+KT+A+PV D + GD V+TRVV Sbjct: 74 EEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVP 133 Query: 130 VRNVSVRELSPLLRQLIDNAGAGNVVHYDPANIILITGRAAVVNRLAEIIKRVDQAGDKE 189 + NV+ R+L+PLLRQL DNAG G+VVHY+P+N++L+TGRAAV+ RL I++RVD AGD+ Sbjct: 134 LTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRS 193 Query: 190 IELVELRNASAAEMVRIVEALNKTTNQKSTPEFLEPKIVADERTNSILISGDPKVRARLK 249 + V L ASAA++V++V LNK T++ + P + +VADERTN++L+SG+P R R+ Sbjct: 194 VVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRII 253 Query: 250 RLIRQLDVEMATKGNNRVVYLKYAKAEDLVDVLKGVSDNLQAEKQAGQKGASSAQRGDVV 309 +I+QLD + AT+GN +V+YLKYAKA DLV+VL G+S +Q+EKQA +A +++ Sbjct: 254 AMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAA--KPVAALDKNII 311 Query: 310 IAAHEATNSLVLTAPPDIMMALQDVISQLDIRRAQVLIEALIVEMSEGDGINLGVQWGSL 369 I AH TN+L++TA PD+M L+ VI+QLDIRR QVL+EA+I E+ + DG+NLG+QW + Sbjct: 312 IKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANK 371 Query: 370 ETGAVIQYGNAGAPIGQVMVGLEEAKDTVEKKPIRDSDTGAIKYYEETTTKGDYSTLASA 429 G + Q+ N+G PI + GA +Y ++ T S+LASA Sbjct: 372 NAG-MTQFTNSGLPISTAI-------------------AGANQYNKDGTVS---SSLASA 408 Query: 430 LKNVNGAAMSIVMGDWTALVSAVASDSNSNILSSPSITVMDNGEASFIVGEEVPVITGST 489 L + NG A G+W L++A++S + ++IL++PSI +DN EA+F VG+EVPV+TGS Sbjct: 409 LSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQ 468 Query: 490 AGSNNDNPFQTVDRKEVGIKLKVVPQINEGDSVQLNIEQEVSNVL----GANGAVDVRFA 545 S DN F TV+RK VGIKLKV PQINEGDSV L IEQEVS+V + + F Sbjct: 469 TTS-GDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFN 527 Query: 546 KRQLNTSVMIQDGQMLVLGGLVDERALESESKVPLLGDIPVLGHLFKSTSTQTQKRNLMV 605 R +N +V++ G+ +V+GGL+D+ ++ KVPLLGDIPV+G LF+STS + KRNLM+ Sbjct: 528 TRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLML 587 Query: 606 FIKPTIIRDGMTADGITQRKYNFIRAEQLYKADQGLKLMSDDKIPVMPAFGQDRKHPAEI 665 FI+PT+IRD + +Y Q + + ++ + QD ++ Sbjct: 588 FIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYPRQDTAAFRQV 647 Query: 666 QAFID 670 A ID Sbjct: 648 SAAID 652
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 522 bits (1347), Expect = 0.0 Identities = 219/407 (53%), Positives = 305/407 (74%), Gaps = 3/407 (0%) Query: 1 MAAFEYKALDAKGKQKKGTIEGDNARQVRQRLKEQGMIPVEVVEAKAKAAKS-SGSVGFK 59 MA + Y+ALDA+GK+ +GT E D+ARQ RQ L+E+G++P+ V E + KS S + + Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 60 RGIK--TAELALITRQLSTLVQSGMPLEECLRAVSEQAEKPRIRTMIAAVRSKVTEGYPL 117 R I+ T++LAL+TRQL+TLV + MPLEE L AV++Q+EKP + ++AAVRSKV EG+ L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 118 ADSLGDYPHVFDELFRSMVAAGEKSGHLDTVLERLAEYVENRQKMRSKLLQAMIYPVVLV 177 AD++ +P F+ L+ +MVAAGE SGHLD VL RLA+Y E RQ+MRS++ QAMIYP VL Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 178 VFAVAIVSFLLATVVPKIIEPIIQMGQELPQSTQFLLAASEFVQEWGLIIFAVLVVCFYG 237 V A+A+VS LL+ VVPK++E I M Q LP ST+ L+ S+ V+ +G + L+ F Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 238 LKLALQKPDFRLSWDRKIISLPLVGKISKGLNTARFARTLSICTSSAIPILEGMRVAVDV 297 ++ L++ R+S+ R+++ LPL+G+I++GLNTAR+ARTLSI +SA+P+L+ MR++ DV Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 298 MSNRYVKQQVLIAADNVREGASLRKALDQTRLFPPMMLHMIASGEQSGELESMLTRAADN 357 MSN Y + ++ +A D VREG SL KAL+QT LFPPMM HMIASGE+SGEL+SML RAADN Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 358 QDQNFESTVNIALGVFTPALIALMAGLVLFIVMATLMPMLEMNNLMS 404 QD+ F S + +ALG+F P L+ MA +VLFIV+A L P+L++N LMS Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 218 bits (558), Expect = 9e-77 Identities = 87/141 (61%), Positives = 107/141 (75%), Gaps = 4/141 (2%) Query: 4 KRSKQHGFTLLEVMVVVVILGILASFVVPNLLGNKEKADQQKAITDIVALENALDMYKLD 63 KQ GFTLLE+MVV+VI+G+LAS VVPNL+GNKEKAD+QKA++DIVALENALDMYKLD Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLD 62 Query: 64 NSVYPTTDQGLDALVTKPS-NPEPRNYRDGGYIKRLPNDPWGNAYQYLSPGDNGTIDIFT 122 N YPTT+QGL++LV P+ P NY GYIKRLP DPWGN Y ++PG++G D+ + Sbjct: 63 NHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLLS 122 Query: 123 LGADGQEGGEGPAADIGNWNM 143 G DG+ G E DI NW + Sbjct: 123 AGPDGEMGTED---DITNWGL 140
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 100 bits (251), Expect = 3e-29 Identities = 43/185 (23%), Positives = 72/185 (38%), Gaps = 37/185 (20%) Query: 3 KHNGFTLIEILLVLVLLSLTAVAVITTLPTSQKDLSKQYAQSFFQRLQLLNEEAVLSGKD 62 + GFTL+E++L+L+L+ ++A V+ P S+ D + Q F +L+ + + + +G+ Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQF 61 Query: 63 FGVRVDDTKKTYTLLSLTAEG-------------WKPLEMKQIPSKTKLEDDIALQLDLG 109 FGV V + + +L W PL ++ + + Sbjct: 62 FGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGSIAGGKLNLAFAQ 121 Query: 110 GGAWDKDDRLFEPGSLFEEMFADETEEKKVKPPQVFIFSSAEVTPFTLSFFPQKGDAFN- 168 G AW D P V IF E+TPF L+ G AFN Sbjct: 122 GEAWTPGDN-----------------------PDVLIFPGGEMTPFRLTLGEAPGIAFNA 158 Query: 169 DGWRV 173 G + Sbjct: 159 RGESL 163
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 28.8 bits (64), Expect = 0.012 Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 11/91 (12%) Query: 17 GFTLIE---VLVSIAIFASLSVAAYQVVSQVQRSNELSQERTQRLNELQRAMVMMDNDF- 72 GFTL+E +L+ + + A + + A+ + + +L +Q+ + F Sbjct: 5 GFTLLEMMLILLLMGVSAGMVLLAFPASRD-DSAAQTLARFEAQLRFVQQRGLQTGQFFG 63 Query: 73 ------RQMALRQTRTNGEDPAGQLIFWSDY 97 R L +G DPA WS Y Sbjct: 64 VSVHPDRWQFLVLEARDGADPAPADDGWSGY 94
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.1 bits (195), Expect = 3e-19 Identities = 27/153 (17%), Positives = 62/153 (40%), Gaps = 9/153 (5%) Query: 2 KILIVEDEHKAGEYLQKGLIESGYVVDLVHDGVDGLYHATSEEYDLILLDIMLPKLDGWQ 61 IL+ +D+ L + L +GY V + + + + DL++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLNTLRSSGIHTPVIMLTAKEQVEDRVRGFELGANDYVVKPYAFAELLARVQNVFRHHIA 121 +L ++ + PV++++A+ ++ E GA DY+ KP+ EL+ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 AQVVASPQTLRVADLE---------LDMIKRVA 145 + L ++ R+ Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLM 157
>PF06580#Sensor histidine kinase Length = 349 Score = 33.7 bits (77), Expect = 0.001 Identities = 25/165 (15%), Positives = 60/165 (36%), Gaps = 35/165 (21%) Query: 298 LIHRHDEVFAVQEEIDRLVAYFEILAEDAEVRIVSSGDGQLYMDKNMFERAVGNLL---- 353 L + + ++ +E+ + +Y ++ ++ + ++ + + V +L Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLA----SIQFEDRLQFENQINPAIMDVQVPPMLVQTL 263 Query: 354 -SNAIRHAYADS----TIVIDVQEVDEQVTVSVSNQGDTIAEQNLPYLFDRFYRADKSRQ 408 N I+H A I++ + + VT+ V N G + Sbjct: 264 VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE-------------- 309 Query: 409 HVGSVGAGLGLS-ITQSIVQAY--EGQIKVTSDKDKTRFVMMLPS 450 G GL + + + Y E QIK++ + K ++++P Sbjct: 310 -----STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 540 bits (1393), Expect = 0.0 Identities = 202/542 (37%), Positives = 324/542 (59%), Gaps = 14/542 (2%) Query: 9 AVVGIRVNDGIAAAPVVLFTHEMPAVPERDFQSEQGEIERVKRAIGVVVQHLQ------- 61 + GI + G+A A + + + EIE++ A+ + L+ Sbjct: 4 KITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTE 63 Query: 62 EQAKQPKGEIFSAHSMMLSDPELWASVESRIQT-GMIAEQAWIESLQTLADEFRQAESQY 120 K EIF+AH ++L DPEL ++ +I+ M AE A E F +++Y Sbjct: 64 ASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEY 123 Query: 121 MREREADVHDIARQVMVEMTGV-TPNAIDIQEPSILLARDLMPSDVAGLDKSKVLGICLS 179 M+ER AD+ D++++V+ + GV T + I E ++++A DL PSD A L+K V G Sbjct: 124 MKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATD 183 Query: 180 EGGKTSHSAILARAMGIPAMVKAQGCLDAVRAGQVVTIDGFRGHLWFSPSDAIQQELEAQ 239 GG+TSHSAI++R++ IPA+V + + ++ G +V +DG G + +P++ + E + Sbjct: 184 IGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEK 243 Query: 240 QIEWQSTRQSALASAQQAAATCDGVHIPVFANIGGPKDIDDALTSGAEGVGLFRTEFLFQ 299 + ++ +Q + + T DG H+ + ANIG PKD+D L +G EG+GL+RTEFL+ Sbjct: 244 RAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLYM 303 Query: 300 NSDELPTEEAQYQVYRDIAAALGDKPLTIRSLDVGGDKPLAAYPMPAEDNPFLGLRGVRL 359 + D+LPTEE Q++ Y+++ + KP+ IR+LD+GGDK L+ +P E NPFLG R +RL Sbjct: 304 DRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAIRL 363 Query: 360 CLQHESLFTAQLRAILRAFHEQPNIQLMIPMVAQVEEVRKVKALLAHQANQL---GLDAT 416 CL+ + +F QLRA+LRA N+++M PM+A +EE+R+ KA++ + ++L G+D + Sbjct: 364 CLEKQDIFRTQLRALLRA-STYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVS 422 Query: 417 H-LPVGIMIEVPAAVLNADALAQEVDFFSIGTNDLTQYVMAADRGNAAVAELVNYFEPSV 475 + VGIM+E+P+ + A+ A+EVDFFSIGTNDL QY MAADR N V+ L + P++ Sbjct: 423 DSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAI 482 Query: 476 LKAIELTCAAGDRAGIPVSMCGEMAGDPNATETLLRVGLQKFSASPSLLPGLKAQIRQLS 535 L+ +++ A G V MCGEMAGD A LL +GL +FS S + + ++Q+ +LS Sbjct: 483 LRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKLS 542 Query: 536 VD 537 + Sbjct: 543 KE 544
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 224 bits (572), Expect = 3e-68 Identities = 86/353 (24%), Positives = 144/353 (40%), Gaps = 40/353 (11%) Query: 323 AQQQIGGSARYTFSTLPVISRKMKHVITVAKRAIKSKSPILITGEEGVGKATLAMAIHNE 382 + L S M+ + V R +++ ++ITGE G GK +A A+H+ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 383 STYKEGPFITLNCRSINTEQLIIETLGYDEG------QGMPSKFELAHGGTLFLEKVEYL 436 + GPF+ +N +I + + E G+++G +FE A GGTLFL+++ + Sbjct: 184 GKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 437 SPDLQAVLLKLLKTGLVSRSDSLRLIPVDFQLITSTASEISEYVTQRSFGRQLYYEISSN 496 D Q LL++L+ G + I D +++ +T ++ + + Q F LYY ++ Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVV 303 Query: 497 ELHIPPLRKRKEDIEFLVQQLISHYERRHNVTISIEPVALEALMNFRWSGNNSELRNRTE 556 L +PPLR R EDI LV+ + E+ + ALE + W GN EL N Sbjct: 304 PLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVR 363 Query: 557 RILLNRSSNLIKLNDIPEDIK------------LNSRHTAENTPV--------------- 589 R+ ++I I +++ S + + V Sbjct: 364 RLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDAL 423 Query: 590 -------ITLEEAERRAIVQAWNQCDGKMHDMAKALQIGRTTLWRKINKFGLQ 635 L E E I+ A G A L + R TL +KI + G+ Sbjct: 424 PPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.8 bits (69), Expect = 0.006 Identities = 13/55 (23%), Positives = 21/55 (38%), Gaps = 1/55 (1%) Query: 125 GLLLWWVDKNAKLVADEYQTGWKKAVFIGIAQALAMIPGTSRSGATITAALYLGF 179 G+L W+ + A+ A +T K + Q LA S + A Y + Sbjct: 527 GVLTWYEEGTAEFFAGSTRTDGIKPR-KSVTQGLAYDRNNRMSLYGVLHAKYGSW 580
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.008 Identities = 16/43 (37%), Positives = 23/43 (53%) Query: 47 MLTGEVGTGKTTVAKAMLANLDESTKAGLILNPTFSSRDLLEA 89 M+TGE GTGK VA+A+ + +N RDL+E+ Sbjct: 164 MITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIES 206
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.008 Identities = 14/76 (18%), Positives = 27/76 (35%), Gaps = 5/76 (6%) Query: 91 RLPRIEKELSEVKEQLANAR-QTSDTEKAGLVTSLETRNQQITDLEKKYSEISDQLTSVE 149 + E + E +L + Q E + S + Q +T + +EI D+L Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESE--ILSAKEEYQLVT--QLFKNEILDKLRQTT 308 Query: 150 TENRELRAKLDTQKDD 165 L +L ++ Sbjct: 309 DNIGLLTLELAKNEER 324
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.015 Identities = 35/182 (19%), Positives = 82/182 (45%), Gaps = 22/182 (12%) Query: 29 ECCSHLVKFFEVSSKGDWEKASEIRAQISHLEK-EADVLK--REIRLKLPRGLFMPVDRT 85 + ++LVK E ++ E +I+ L+K DVL+ E+ ++ F +D Sbjct: 61 DSINNLVKT-EFTN----ETLDKIQQTQDLLKKIPKDVLEIYSELGGEI---YFTDIDLV 112 Query: 86 DMLEL--LTQQDKLANLAKDIAGR---VYGRQLVIPEALQPNFLAYVQRCLDAANQAQKV 140 + EL L++++K + + G R + + P + ++ + Q+++V Sbjct: 113 EHKELQDLSEEEKNS---MNSRGEKVPFASRFVFEKKRETPKLIINIKDYAINSEQSKEV 169 Query: 141 INELDELLETGFKGREVTLVAEMIHQLDVIEDDTDAMQIELRQQLMAIESEMNP--IDVM 198 E+ + + ++ +L E ++ + + DD+D+ + Q+ + E+N ID+ Sbjct: 170 YYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSDSSDLLFSQKFKE-KLELNNKSIDIN 228 Query: 199 FL 200 F+ Sbjct: 229 FI 230
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 33.8 bits (77), Expect = 0.002 Identities = 14/93 (15%), Positives = 43/93 (46%) Query: 191 SAQEEFNEIDQLATAMSEMSSTVQTVADHAQTASSLTEQASTQAVTGQQFLQSTVAKMSE 250 A+ + + + +S + + T + + +Q S V+ + ++++ +++ Sbjct: 131 GAENIGDNLGKAGGILSTFQNFLGTALSSMKIDELIKKQKSGGNVSSSELAKASIELINQ 190 Query: 251 LSSDIASSAQAVNQVEERVESIGSVVGTIQGIS 283 L +AS VN +++ ++GSV+ + ++ Sbjct: 191 LVDTVASLNNNVNSFSQQLNTLGSVLSNTKHLN 223
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 29.8 bits (67), Expect = 0.015 Identities = 10/28 (35%), Positives = 15/28 (53%) Query: 347 GCFDILHAGHVSYLNHAAELGDRLIVAV 374 G FD + GH+ + L D++ VAV Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAV 34
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 27.7 bits (61), Expect = 0.036 Identities = 29/139 (20%), Positives = 53/139 (38%), Gaps = 29/139 (20%) Query: 63 LPYDPKTDQVVIIEQIRIGALEHEHPWQLEIVAGMIDRDESAEEVIRREAEEEAGITVGR 122 +P +PKT V+ + + +E Q++ A + A ++R + Sbjct: 221 VPSEPKTVYVICLRENGSTIYPNEVSAQMQDAANSV----YAVHGLKRY------VNFHF 270 Query: 123 VASVTSYYPSSGGCSEKLDVFVGEVDAS-KAHGIHGLDYEDEDIRVHVLSREQAYQWVKD 181 V T Y SG E L+ F + ++ KA G Y+D Q Y ++ Sbjct: 271 VLYTTEYSCPSGDAKEGLEGFTASLKSNPKAEG-----YDD-----------QIYFLIRW 314 Query: 182 GIFENGASIIALQWLQLNH 200 G ++N I+ + W + Sbjct: 315 GTWDN--KILGMSWFNSYN 331
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 33.8 bits (77), Expect = 1e-04 Identities = 14/32 (43%), Positives = 18/32 (56%) Query: 5 TNDSVVTLHFTIKMKDGSVADSTHNMGKPAKF 36 VT+ +T + DG+V DST GKPA F Sbjct: 142 GKSDTVTVEYTGTLIDGTVFDSTEKAGKPATF 173
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 4e-14 Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 7/116 (6%) Query: 3 TALVIDDEQFAREELAELLDETG-QVEVVGDASNAILGLKKINELKPDVVFLDIQMPQVT 61 T LV DD+ R L + L G V + +A+ + I D+V D+ MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATL---WRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GIELLGML-DPETMPYVVFVTAYDQY--AIQAFEDNAFDYLLKPVDPCRLNKTVKR 114 +LL + V+ ++A + + AI+A E A+DYL KP D L + R Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF06580#Sensor histidine kinase Length = 349 Score = 222 bits (566), Expect = 1e-69 Identities = 67/185 (36%), Positives = 109/185 (58%), Gaps = 1/185 (0%) Query: 355 DYQQQQALLAQAEIKLLHAQVNPHFLFNALNTISAITRRDPDKARELIQNLSHFFRSNLK 414 D + ++ +A++ L AQ+NPHF+FNALN I A+ DP KARE++ +LS R +L+ Sbjct: 150 DQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLR 209 Query: 415 -QNINTVTLKEELAHVNSYLSIEKARFTDRLEVEIDIDPELLDIKLPSFTLQPLVENAIK 473 N V+L +EL V+SYL + +F DRL+ E I+P ++D+++P +Q LVEN IK Sbjct: 210 YSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIK 269 Query: 474 HGISNMLEGGKVKIYSEMHPQGHLITVEDNAGSFQPPKDNHSGLGLEIVDKRLTNQFGRD 533 HGI+ + +GGK+ + + VE+ +G GL+ V +RL +G + Sbjct: 270 HGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTE 329 Query: 534 SALKI 538 + +K+ Sbjct: 330 AQIKL 334
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 28.8 bits (64), Expect = 0.004 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 17/72 (23%) Query: 1 MKKYFLVALVL--LPLTASAGNVLKDTIKA----KRKYDHNKHQITNTLNNTK------- 47 MKK L+AL L LP+ A A L IKA R +H +++ ++ Sbjct: 1 MKKS-LIALTLAALPVAAMADVTLYGAIKAGVQTYRSVEHTDGKVSKVETGSEIADFGSK 59 Query: 48 ---RDIEDLTNG 56 + EDL NG Sbjct: 60 IGFKGQEDLGNG 71
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.3 bits (76), Expect = 0.002 Identities = 29/163 (17%), Positives = 57/163 (34%), Gaps = 27/163 (16%) Query: 148 QYAGHLNLLKSTRSAYQHWRQADNNLKQLKENSQQNQAQKQLLEYQIKELNELSLGEEE- 206 + +L+K S +Q N Q + N + +A++ + +I LS E+ Sbjct: 183 EVLRLTSLIKEQFSTWQ------NQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSR 236 Query: 207 -------FAE--------LEQEHKRLSNSGELAATCQQALELIYEGEEVNALGILQSA-- 249 + LEQE+K + EL Q ++ E L + Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF 296 Query: 250 -NHSLIQLAELDEKLAELPNMLADAMIQLEETKNELRSYLDGI 291 N L +L + + + L LA + + + +R+ + Sbjct: 297 KNEILDKLRQTTDNIGLLTLELAKNEERQQAS--VIRAPVSVK 337
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.5 bits (66), Expect = 0.002 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 5/58 (8%) Query: 4 KQKGFNLLEVLISFLLIGV-GALGLTKLNVYLEQ-ESDYAIESIEALRLAENKLEWFR 59 KQ+GF LLE+++ ++IGV +L + L E+ + A+ I AL EN L+ ++ Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVAL---ENALDMYK 60
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 27.0 bits (59), Expect = 0.004 Identities = 9/19 (47%), Positives = 16/19 (84%), Gaps = 1/19 (5%) Query: 34 GVAFLQN-MSPIMEKIIEP 51 GV+F+Q ++PIME +++P Sbjct: 362 GVSFIQQALNPIMEHVLKP 380
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 31.1 bits (70), Expect = 0.001 Identities = 9/32 (28%), Positives = 15/32 (46%) Query: 98 NVNVMEEMANMISASRAYQTNVQVADSSKQML 129 VN+ EE N+ + Y N QV ++ + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIF 539
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 39.2 bits (91), Expect = 3e-05 Identities = 15/33 (45%), Positives = 21/33 (63%) Query: 3 YVSLSGLSAAQLDLNTTSNNIANANTYGFKESR 35 ++SGL+AAQ LNT SNNI++ N G+ Sbjct: 5 NNAMSGLNAAQAALNTASNNISSYNVAGYTRQT 37 Score = 35.7 bits (82), Expect = 3e-04 Identities = 11/49 (22%), Positives = 26/49 (53%) Query: 389 TINNGMLEQSNIDMTQELVDLISAQRNFQANSRSLEVHNQLQQNILQIR 437 ++N S +++ +E +L Q+ + AN++ L+ N + ++ IR Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 10/47 (21%), Positives = 22/47 (46%) Query: 214 EIRQSMLEASNVNVTEELVNMIEAQRVYEMNSKVISSVDKMMSFVNQ 260 ++ S VN+ EE N+ Q+ Y N++V+ + + + + Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 39.6 bits (92), Expect = 9e-06 Identities = 17/77 (22%), Positives = 34/77 (44%), Gaps = 14/77 (18%) Query: 5 LWVSKTGLDAQQTNIATISNNLANASTVGYKKSRAVFEDLFYQNINQPGGQSSQNTELPS 64 + + +GL+A Q + T SNN+++ + GY + + + N+ L + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTLGA 49 Query: 65 GLMLGAGSKVVATQKVH 81 G +G G V Q+ + Sbjct: 50 GGWVGNGVYVSGVQREY 66
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 147 bits (372), Expect = 9e-46 Identities = 75/204 (36%), Positives = 108/204 (52%), Gaps = 13/204 (6%) Query: 65 AWAPIHPKQK--------PEHYAAATGSLF-SPEHIT----DLYDDSKPRGIGDIITVTL 111 AW P P + P A GS+F S + I L++D +PR IGD +T+ L Sbjct: 23 AWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVL 82 Query: 112 DETTSATKSANADLSKTNEAQMDPLQVGGEELKVGGKYNFSYDLNNTNTFAGDSSAKQSN 171 E SA+KS++A+ S+ + V + G + + NTF G A SN Sbjct: 83 QENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASN 142 Query: 172 SISGYITVEVIEVLANGNLVIRGEKWMTLNTGDEYIRLSGTIRPDDINFDNTIASNRVSN 231 + SG +TV V +VL NGNL + GEK + +N G E+IR SG + P I+ NT+ S +V++ Sbjct: 143 TFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVAD 202 Query: 232 ARIQYSGTGLSQDMQEPGFLARFF 255 ARI+Y G G + Q G+L RFF Sbjct: 203 ARIEYVGNGYINEAQNMGWLQRFF 226
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 415 bits (1068), Expect = e-147 Identities = 166/367 (45%), Positives = 226/367 (61%), Gaps = 15/367 (4%) Query: 6 LLLMSVALFSTA---AQAARIKDVAQVAGVRSNQLVGYGLVSGLPGTGE---ANPFTEQS 59 L+ ++ ST A +RIKD+A + R NQL+GYGLV GL GTG+ ++PFTEQS Sbjct: 11 LVFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQS 70 Query: 60 FAAMLQNFGIQLPPGTKPKIKNVAAVMVTAELPPFSKPGQQVDVTVSSIGSAKSLRGGTL 119 AMLQN GI G KN+AAVMVTA LPPF+ PG +VDVTVSS+G A SLRGG L Sbjct: 71 MRAMLQNLGITTQGGQ-SNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNL 129 Query: 120 LQTFLKGLDGQVYAVAQGNLVVSGFSAEGADGSKIVGNNPTVGLISSGATVEREIPNPFG 179 + T L G DGQ+YAVAQG L+V+GFSA+G D + + T + +GA +ERE+P+ F Sbjct: 130 IMTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFK 188 Query: 180 RGDYITFNLLESDFTTAQRMADAVNNF----LGPQMASAVDATSVRVRAPRDVSQRVAFL 235 + L DF+TA R+AD VN F G +A D+ + V+ PR V+ + Sbjct: 189 DSVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPR-VADLTRLM 247 Query: 236 SAIENLEFDPADGAAKIIVNSRTGTIVVGKHVRLKPAAVTHGGMTVAIKENLNVSQPNSF 295 + IENL + D AK+++N RTGTIV+G VR+ AV++G +TV + E+ V QP F Sbjct: 248 AEIENLTVET-DTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPF 306 Query: 296 SGGQTVVVPDSDIEVTEEKGKMFKFEPGLTLDDLVRAVNEVGAAPSDLMAILQALKQAGA 355 S GQT V P +DI +E K+ E G L LV +N +G ++AILQ +K AGA Sbjct: 307 SRGQTAVQPQTDIMAMQEGSKVAIVE-GPDLRTLVAGLNSIGLKADGIIAILQGIKSAGA 365 Query: 356 IEGQLII 362 ++ +L++ Sbjct: 366 LQAELVL 372
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 270 bits (690), Expect = 6e-92 Identities = 98/299 (32%), Positives = 156/299 (52%), Gaps = 18/299 (6%) Query: 13 DISSLDSLRQKAVKEGKDGEQEA--LHAAARQFESIFTSMMLKSMREANEGFESNIMNSQ 70 D SL+ L+ KA GE A + ARQ E +F MMLKSMR+A + + +S+ Sbjct: 14 DAQSLNELKAKA------GEDPAANIRPVARQVEGMFVQMMLKSMRDALP--KDGLFSSE 65 Query: 71 NEKFYRQMLDEQMASELSANGSMGLADMIVAQLTAGQGNDKSETAMRDAANSAVEYRRVD 130 + + Y M D+Q+A +++A +GLA+M+V Q+T Q + T R Sbjct: 66 HTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLETVVRYQ 125 Query: 131 PKKAREIEKRLIESGELSRTSHTPAKFDSPESFVNSMKPYAEKAAKALGVEPSLLLAQAA 190 + ++ ++ + DS ++F+ + A+ A++ GV L+LAQAA Sbjct: 126 NQALSQLVQKAVPRNYDDSLP-----GDS-KAFLAQLSLPAQLASQQSGVPHHLILAQAA 179 Query: 191 LETGWGQKVVQNARGS-SNNLFNIKADRSWQGDKVTTQTLEFHDNTPVKETAAFRSYSNY 249 LE+GWGQ+ ++ G S NLF +KA +W+G T E+ + K A FR YS+Y Sbjct: 180 LESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSY 239 Query: 250 QDSFNDYVRFLNDNPRYETALQQRGDSESFIRGIHRAGYATDPTYADKVLQVKQKIESM 308 ++ +DYV L NPRY A+ +E + + AGYATDP YA K+ + Q+++S+ Sbjct: 240 LEALSDYVGLLTRNPRY-AAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSI 297
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 539 bits (1390), Expect = 0.0 Identities = 113/446 (25%), Positives = 207/446 (46%), Gaps = 17/446 (3%) Query: 3 SDLLNVGTQSVLTAQRQLNTTGHNISNVNTEGYSRQSVIQGTNDPRMFGGSTYGMGVHVE 62 S L+N + AQ LNT +NIS+ N GY+RQ+ I + + G G GV+V Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 63 NVRRSWDQFAVNELNLSSTSNANKTDTQDNLDMLSSMLSSVASKKIPENLNEWFDAVKTM 122 V+R +D F N+L + T ++ T + + + +MLS+ ++ + + ++F +++T+ Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLST-STSSLATQMQDFFTSLQTL 119 Query: 123 ADTPNDLGARKVVLEKAKIFSDTLNDFHETVRLQSDVTNKKLDMGIERINQLALEIRDIH 182 D AR+ ++ K++ + + +R Q N + +++IN A +I ++ Sbjct: 120 VSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLN 179 Query: 183 RLMMRTPG-----PHNDLMDQHEKLITELSEYTKVTVTPRKNAEGFNVHIGNGHTLVSGT 237 + R G N+L+DQ ++L++EL++ V V+ + +N+ + NG++LV G+ Sbjct: 180 DQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGT-YNITMANGYSLVQGS 238 Query: 238 EASQLKMIDGYPDVHQRRLAMVEGDG--IKAIKADDMDGKIGALLDMRDKHIPQLLDEMG 295 A QL + D + +A V+G I+ + G +G +L R + + Q + +G Sbjct: 239 TARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLG 298 Query: 296 RLATGFSYKVNQLQSQGLDLNGKIGKDVFTDVNSELVAKSRVFTAPNSKADVAV--YVDD 353 +LA F+ N G D NG G+D F + K V +K DVA+ V D Sbjct: 299 QLALAFAEAFNTQHKAGFDANGDAGEDFFA------IGKPAVLQNTKNKGDVAIGATVTD 352 Query: 354 ISALKGGEYALRFDGDRYSVTTPKGEQVQIDIDQSDSTFVLDGMRVQIGEGLAAGERVLL 413 SA+ +Y + FD +++ VT ++ DG+ + A + L Sbjct: 353 ASAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTL 412 Query: 414 RPTRSGAAIIKMETNDAKSIAAQSYE 439 +P + + D IA S E Sbjct: 413 KPVSDAIVNMDVLITDEAKIAMASEE 438 Score = 143 bits (363), Expect = 9e-39 Identities = 34/105 (32%), Positives = 60/105 (57%) Query: 542 EGGNGNLRKMQQLQTNKMMDGKSSTLIDVYHNLNTEVGLKSATANRLASVARLEHEAAQE 601 + N N + + LQ+N G + + D Y +L +++G K+AT ++ Sbjct: 442 DSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLSN 501 Query: 602 RVASIAGVNLDEEAANMMKFQQAYMASSRVMQAANDTFNTILQLR 646 + SI+GVNLDEE N+ +FQQ Y+A+++V+Q AN F+ ++ +R Sbjct: 502 QQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546
>FLAGELLIN#Flagellin signature. Length = 507 Score = 36.9 bits (85), Expect = 1e-04 Identities = 26/183 (14%), Positives = 57/183 (31%), Gaps = 3/183 (1%) Query: 202 QSGSDLLLSKATNVDAKDTASYRVTFVDMNNGKFGYQLERNGKVVDADEFSPEKGIEYKG 261 + + + + + + V+ + K+ D + + KG Sbjct: 312 VADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKIT 371 Query: 262 LKVHVKGQITPGDSIGIEKRESFSIFDTFKEAMSWSDKSVSDTSATAKLHQMTEEFQAAF 321 + GD + + ++F + + + +A +A Sbjct: 372 VNGAEYTANAAGDKVTLA---GKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSAL 428 Query: 322 IHLNKARTDVGARLSTLDIQEQNHEDFNLSLAKAKSNFEDLDYSKAVIEFSENSRALQAS 381 ++ R+ +GA + D N + +L A+S ED DY+ V S+ QA Sbjct: 429 SKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAG 488 Query: 382 QQA 384 Sbjct: 489 TSV 491 Score = 31.6 bits (71), Expect = 0.006 Identities = 34/227 (14%), Positives = 75/227 (33%), Gaps = 13/227 (5%) Query: 9 HNYQSV--QNDLRRQENKIHHNQEQLASGKKLLKPSDDPLAAHYIQNIGQQQEQLKQYLS 66 N S+ QN+L + ++ + E+L+SG ++ DD + L Q Sbjct: 6 TNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASR 65 Query: 67 SIVLVRNRLENHEVNIANAESFADESKRLTMEMINGAFSAEDRQAKKRELEEIANNFLNL 126 + + + E + + + L+++ NG S D ++ + E+++ + Sbjct: 66 NANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRV 125 Query: 127 VNAQDESGNYVFAGTKPKSQPFYRDKDGSVQYAGDDYQR-KMKVSSMLDMPMNDPGSKLF 185 N +G V + +Q +D + + + + + G + Sbjct: 126 SNQTQFNGVKVLSQDNQM----------KIQVGANDGETITIDLQKIDVKSLGLDGFNVN 175 Query: 186 MEIPNPFGDYQPSYDLQSGSDLLLSKATNVDAKDTASYRVTFVDMNN 232 GD + S+ +G D A + VT Sbjct: 176 GPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPT 222
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 457 bits (1177), Expect = e-161 Identities = 166/479 (34%), Positives = 245/479 (51%), Gaps = 50/479 (10%) Query: 4 VFFIDDEADLRFAIEQTFELADIEATFFSDAESALLAMKQSDEAGVIVTDICLPGISGMD 63 + DD+A +R + Q A + S+A + + + + ++VTD+ +P + D Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI-AAGDGDLVVTDVVMPDENAFD 64 Query: 64 LLTTLVQRDPNLPVIMITGHGDISMAVNALHQGAYDFIEKPFAPEHLVETVKRAIERRQL 123 LL + + P+LPV++++ A+ A +GAYD++ KPF L+ + RA+ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK- 123 Query: 124 TNENEKLRQSLKASQTLGPRIIGETTSIQTLRETITHIADTDADILLFGETGTGKELIAR 183 + L+ G ++G + ++Q + + + TD +++ GE+GTGKEL+AR Sbjct: 124 -----RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVAR 178 Query: 184 SLHEQSSRRNNNFVAVNCGAVPENLIESELYGHEKGAFTGADSRRIGKFEFAQGGTLFLD 243 +LH+ RRN FVA+N A+P +LIESEL+GHEKGAFTGA +R G+FE A+GGTLFLD Sbjct: 179 ALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLD 238 Query: 244 EIESMPIQAQIRLLRVLQERVIERVGSNELLPLDIRVVAATKVDLKRAAEQGTFRQDLYY 303 EI MP+ AQ RLLRVLQ+ VG + D+R+VAAT DLK++ QG FR+DLYY Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYY 298 Query: 304 RLNVVTLDLPPLRERKEDIPALFHHFLLVAASRYGKSSPSLSAQDLAQLMAHDWPGNVRE 363 RLNVV L LPPLR+R EDIP L HF+ A + G + L + AH WPGNVRE Sbjct: 299 RLNVVPLRLPPLRDRAEDIPDLVRHFVQ-QAEKEGLDVKRFDQEALELMKAHPWPGNVRE 357 Query: 364 LRNAAERFVLL----------------------------GKLIQLGEPSSIPASTSS--- 392 L N R L + L ++ + Sbjct: 358 LENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFA 417 Query: 393 -----------LAEQVAEFEKAAIENALLENNGSIKQTMEQLNVPRKTLYDKMQRYQID 440 +AE E I AL G+ + + L + R TL K++ + Sbjct: 418 SFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 2e-04 Identities = 36/192 (18%), Positives = 76/192 (39%), Gaps = 24/192 (12%) Query: 349 QRTETEQTLRLTQDELIQAAKLAVLGQMSASIS-HELNNPLAAIRSFAENGKLFLQKEKY 407 + + + Q ++ A+ A L + A I+ H + N L IR+ Sbjct: 139 HFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDP-------- 190 Query: 408 DRVEDNLTRISALTDRMANISQQLRSFAKKASGNELTQTRLLPVIASSKELMKPAFKSAR 467 + + LT +S L +R + ++ +++ L V+ S +L F+ R Sbjct: 191 TKAREMLTSLSEL----------MRYSLRYSNARQVSLADELTVVDSYLQLASIQFED-R 239 Query: 468 VLLATELPTDDIEVQINTIQLEQVLVNLLTNAIEAVKEQQDKQVWLLVETDTDENKVMIH 527 + ++ ++VQ+ + + Q LV N I+ Q + +L++ D V + Sbjct: 240 LQFENQINPAIMDVQVPPMLV-QTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLE 295 Query: 528 VDDNGPGLGSHT 539 V++ G +T Sbjct: 296 VENTGSLALKNT 307
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.1 bits (73), Expect = 0.009 Identities = 40/215 (18%), Positives = 76/215 (35%), Gaps = 45/215 (20%) Query: 261 KMPQEAREKTEQELQKLKMMSP---MSAEATV----------VRSYIDWMVSVPWTKRSK 307 MP E ++K + P MSA+ T Y+ P+ ++ Sbjct: 56 VMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYL----PKPF-DLTE 110 Query: 308 VKKNLAKAEEILNEDHYGLERVKERILEYL-------AVQNRINKL---KGPILCLVGPP 357 + + +A LE + + + + + +L ++ + G Sbjct: 111 LIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLM-ITGES 169 Query: 358 GVGKTSLGRSIASATGRK---YVRMALGGVRD---EAEIRGHRRTYIGSLPGKLIQKMSK 411 G GK + R++ R+ +V + + + E+E+ GH + G+ G + + Sbjct: 170 GTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEK---GAFTGAQTRSTGR 226 Query: 412 VGVKN--PLFLLDEIDKMSSDMRGDPASALLEVLD 444 LF LDEI M D + + LL VL Sbjct: 227 FEQAEGGTLF-LDEIGDMPMDAQ----TRLLRVLQ 256
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 122 bits (308), Expect = 2e-40 Identities = 50/87 (57%), Positives = 64/87 (73%) Query: 2 NKTQLVEQIAENADISKASAGRALDAFIEAVSGTLQSGDQVALVGFGTFSVRTRAARTGR 61 NK L+ ++AE +++K + A+DA AVS L G++V L+GFG F VR RAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPKTGEEIQIAEAKVPAFKAGKALKDA 88 NP+TGEEI+I +KVPAFKAGKALKDA Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDA 89
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 26.4 bits (58), Expect = 0.018 Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 3/35 (8%) Query: 54 GIGEKKAQSIVDYRTEHGPFKTAADLTNVKGIGEA 88 G+ E++AQS+VDY G AD + +G+GE+ Sbjct: 272 GLSERRAQSVVDYLISKG---IPADKISARGMGES 303
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 30.2 bits (68), Expect = 0.018 Identities = 12/46 (26%), Positives = 20/46 (43%), Gaps = 2/46 (4%) Query: 115 GEVALNYMMRDHGGFEGNAQTFRIVTKLEPYTEHFGMNLSRRTLLG 160 L R H F N+ +R+ L P +F + LS+ ++G Sbjct: 134 HSRPLTDFARSH--FLSNSSAYRMREALIPLLRNFELKLSKNKIVG 177
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 34.6 bits (79), Expect = 1e-04 Identities = 16/106 (15%), Positives = 32/106 (30%), Gaps = 5/106 (4%) Query: 1 MARRNDHTREELINLTLTTVKNFLDENSYHELSLRKIANMIGYVPSTLVNIFGNYNLLLL 60 + TR+ ++++ L + SL +IA G + F + + L Sbjct: 5 TKQEAQETRQHILDVALR----LFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 HAVAQTLDELSQ-EALNATKSSKDAHQALFELAYCYHDFAQKHPYR 105 + + + E K D L E+ + R Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERR 106
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 50.6 bits (121), Expect = 5e-09 Identities = 31/206 (15%), Positives = 74/206 (35%), Gaps = 21/206 (10%) Query: 71 VKQIAVKANQNVQQNQLLIQLDDDKAQ--AALVEAKAYLKDEERKLKEFQRLVKRNAITQ 128 + + A+ + ++Q ++ ++ + L + ++ + + + + +L K + + Sbjct: 244 LHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK 303 Query: 129 TEIDAQKASVEIAQARLDAAKANLADLHITAPFSGTVGFID-FSRGKMVSAGTELLTL-D 186 + L + I AP S V + + G +V+ L+ + Sbjct: 304 LR-QTTDNIGLL-TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP 361 Query: 187 DLSVMELDLQIPERYLSMLSVGMEVAAKTSAWGEQRFSGKVTGIDTRISA-----ETLNL 241 + +E+ + + + ++VG K A+ R+ G + G I+ + L L Sbjct: 362 EDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRY-GYLVGKVKNINLDAIEDQRLGL 420 Query: 242 --RVRIEFD-------NPENQLKPGM 258 V I + N L GM Sbjct: 421 VFNVIISIEENCLSTGNKNIPLSSGM 446 Score = 39.4 bits (92), Expect = 2e-05 Identities = 15/65 (23%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Query: 44 EINQSLSLIGKLKAA-ESVVVASEVAGKVKQIAVKANQNVQQNQLLIQLDDDKAQAALVE 102 ++ + GKL + S + VK+I VK ++V++ +L++L A+A ++ Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 103 AKAYL 107 ++ L Sbjct: 139 TQSSL 143
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 780 bits (2016), Expect = 0.0 Identities = 308/1032 (29%), Positives = 517/1032 (50%), Gaps = 28/1032 (2%) Query: 3 LSDVSVKRPVAALVLSMLLCVFGFVSFTKLAVREMPDIESPVVSISTRYEGASATIIESQ 62 +++ ++RP+ A VL+++L + G ++ +L V + P I P VS+S Y GA A ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 ITSVLEDQLSGISGIDEISSTTRNSMS-RITITFELGYDLNTGVSDVRDAVARAQRSLPD 121 +T V+E ++GI + +SST+ ++ S IT+TF+ G D + V++ + A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 EADDPIVYKNNGSGEASLYINLSSSEMDRTQ--LTDYAERVLMDRFSLITGVSSIDLSGG 179 E + S + S TQ ++DY + D S + GV + L G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 LYKVMYVKLKPELMAGRAVTASDITSALRSENLESPGGEVRNDSTV------MSVRTART 233 Y + + L +L+ +T D+ + L+ +N + G++ + S+ Sbjct: 181 QYAMR-IWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 YNTPEDFQYLVIKRASDNTPIYLKDVADVFIGAENENSTFKSDGVVNISLGVVPQSDANP 293 + PE+F + ++ SD + + LKDVA V +G EN N + +G LG+ + AN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 LEVAKLVRSEVDNIQKFLPEGTRLAIDYDATVFIERSIEEVYSTLFITGGLVILVLYIFI 353 L+ AK +++++ +Q F P+G ++ YD T F++ SI EV TLF LV LV+Y+F+ Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 GQARATLIPAVTVPVSLISSFIAAYYFGFSINLITLMALILSIGLVVDDAIVVVENIFHH 413 RATLIP + VPV L+ +F FG+SIN +T+ ++L+IGL+VDDAIVVVEN+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 I-ERGESPLLAAYKGTREVGFAVIATTLVLVMVFLPISFMDGMVGLLFTEFSVLLAMSVI 472 + E P A K ++ A++ +VL VF+P++F G G ++ +FS+ + ++ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 FSSLIALTLTPVLGSQILKANVK-----PNRFNEVVDRLFSKLENGYRSLLKGALKARLA 527 S L+AL LTP L + +LK F + F N Y + + L + Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 528 APLVILACMGGSYFLMNQVPAQLTPQEDRGVIFAFVRGADATSYNRMSANMDIVEDRLMP 587 L+ + G L ++P+ P+ED+GV ++ + R +D V D + Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 588 LLGQGYLKSFSIQTPAFGGQAGDQTGFVIMILEDWNERDV---TAQEALNKVRGALAGIP 644 F++ +F GQ G + L+ W ER+ +A+ +++ + L I Sbjct: 600 NEKANVESVFTVNGFSFSGQ-AQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 645 DVRVFPF-MPGFQG-GSSEPVQFVL---GGSDYDELLVWAELLKNKAEESP-MMEGAEID 698 D V PF MP G++ F L G +D L L A + P + + Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 699 YSEKTPELLVTVDKQRAAELGVSVKDISDTLEIMLGGKSETTYVERGEEYDVYLRGDENS 758 E T + + VD+++A LGVS+ DI+ T+ LGG +++RG +Y++ D Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 759 FNNAADLSQIYLRTNSGELVTLDTVTKIEEVAASIRLSHYNKQKSITITANLSEGYTLGE 818 D+ ++Y+R+ +GE+V T V S RL YN S+ I + G + G+ Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 819 ALNYLDQQAIDNLPGDISVSYSGESKDFKENQASVAVVFALALLVAYLVLAAQFESFVNP 878 A+ ++ A LP I ++G S + + + A++ +V +L LAA +ES+ P Sbjct: 839 AMALMENLA-SKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIP 897 Query: 879 LVVMFTVPMGVFGGFLGLVVMGQGMNIYSQIGMIMLIGMVTKNGILIVEFANQLRDR-GV 937 + VM VP+G+ G L + Q ++Y +G++ IG+ KN ILIVEFA L ++ G Sbjct: 898 VSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGK 957 Query: 938 EFEKAIIDAAARRLRPILMTAFTTLAGAIPLIVSTGAGYESRIAVGTVIFFGMGFATLVT 997 +A + A RLRPILMT+ + G +PL +S GAG ++ AVG + GM ATL+ Sbjct: 958 GVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLA 1017 Query: 998 LFVIPAMYRLIS 1009 +F +P + +I Sbjct: 1018 IFFVPVFFVVIR 1029
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 38.8 bits (90), Expect = 6e-06 Identities = 38/194 (19%), Positives = 66/194 (34%), Gaps = 9/194 (4%) Query: 2 KNAILLLSALTISVPTFAAQEQTHQSYFYLGTGNVGF-DTPYFGSDRDNEWSTPHITVGW 60 K AI + AL A + + Y G + DT + ++ + Sbjct: 3 KTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFG 62 Query: 61 GYYVNQYLAFE-GVLRYSQNELKNDTLKTDLDLHYYQAGMSAVLTSDNLGDTPLSLFGRV 119 GY VN Y+ FE G + K + + Q + D L ++ R+ Sbjct: 63 GYQVNPYVGFEMGYDWLGRMPYKG---SVENGAYKAQGVQLTAKLGYPITDD-LDIYTRL 118 Query: 120 TALGTQAEMYVPNAQKVTDDSGALFNVGAGVHWDMSKDIWLRAEYIY--NVADMGFEDFY 177 + +A+ N D+G GV + ++ +I R EY + N+ D Sbjct: 119 GGMVWRAD-TKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTR 177 Query: 178 DSYEGLQISLGKRF 191 L + + RF Sbjct: 178 PDNGMLSLGVSYRF 191
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 349 bits (897), Expect = e-120 Identities = 122/341 (35%), Positives = 187/341 (54%), Gaps = 13/341 (3%) Query: 3 QNLIGESPAFLAVLDKVSQLAPIERPVLIIGERGTGKELIAQRLHYLSKRWDKPLLSLNC 62 L+G S A + +++L + ++I GE GTGKEL+A+ LH KR + P +++N Sbjct: 137 MPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINM 196 Query: 63 ATLSEGLIDSELFGHESGSFTGSKGKHKGRFERAEGGTLFLDELATAPLLVQEKLLRVIE 122 A + LI+SELFGHE G+FTG++ + GRFE+AEGGTLFLDE+ P+ Q +LLRV++ Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQ 256 Query: 123 YGEYERVGGHTALNADVRLVCATNADLPRLAEQGDFRADLLDRLAFDVIMLPPLRERKED 182 GEY VGG T + +DVR+V ATN DL + QG FR DL RL + LPPLR+R ED Sbjct: 257 QGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAED 316 Query: 183 ILSLAEHYAMKMCRELQLEYFVGFTHQAQQALLDYSWPGNVRELKNVIERAIYQHGLNAE 242 I L H+ + +E F +A + + + WPGNVREL+N++ R + + Sbjct: 317 IPDLVRHFVQQAEKEGLDV--KRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVI 374 Query: 243 PIDELIFNPFATGWNNALGHTAANEEPQEEASSQTTSIHFPL-----------DYKQWQE 291 + + + ++ + AA + + ++ Y + Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLA 434 Query: 292 EQDINLLNRALEEAKFNQRQAAELLGLSYHQLRGMVRKYGL 332 E + L+ AL + NQ +AA+LLGL+ + LR +R+ G+ Sbjct: 435 EMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 26.1 bits (57), Expect = 0.015 Identities = 7/29 (24%), Positives = 16/29 (55%) Query: 37 SSQDLERLQVLSEKAEAMQSRVDTLERIL 65 +++D Q L K+E + ++ T ++ L Sbjct: 122 NAEDPAARQALIGKSEGLVNQFKTTDQYL 150
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 45.2 bits (107), Expect = 2e-07 Identities = 27/182 (14%), Positives = 57/182 (31%), Gaps = 27/182 (14%) Query: 92 EYSLLEKQARANFALADVQYKRYKKLRKDQVVSEQDFDEAKANHNSAKAQWDQAKANLRY 151 E +L + + + KLR + N + + + + Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLR-----------QTTDNIGLLTLELAKNEERQQA 327 Query: 152 TQLVAPYDGTISYLPAENH-EYVAAKEGVMNI-QTNQVMKVIFQLPDYLLNRYTQGVNVS 209 + + AP + L V E +M I + ++V + + + G N Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNA- 386 Query: 210 AKMIFDAFPERSF---DLTFQEI--DTEADPKTG-SYKVTMVMERP------PELGILPG 257 + +AFP + + I D D + G + V + +E + + G Sbjct: 387 -IIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSG 445 Query: 258 MS 259 M+ Sbjct: 446 MA 447 Score = 38.7 bits (90), Expect = 3e-05 Identities = 22/114 (19%), Positives = 41/114 (35%), Gaps = 17/114 (14%) Query: 54 AGDRAVLAFRVPGLLQSIEVNEGQVVKKGDVLAVLNPDEYSLLEKQARANFALADVQYKR 113 +G + +++ I V EG+ V+KGDVL L + +++ A ++ R Sbjct: 93 SGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTR 152 Query: 114 YKKLRKD-----------------QVVSEQDFDEAKANHNSAKAQWDQAKANLR 150 Y+ L + Q VSE++ + + W K Sbjct: 153 YQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKE 206
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.7 bits (103), Expect = 7e-07 Identities = 25/132 (18%), Positives = 42/132 (31%), Gaps = 30/132 (22%) Query: 67 GEVSRVMVREGDKVQKGAVIATLDPTDYQLDVDNATARF-----------SVVDSQYRRS 115 V ++V+EG+ V+KG V+ L + D + + S Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNK 164 Query: 116 RPLVD-----------------KGLLAKSQFDEIAAQRQIALAELELAKLRLSFTTLKAP 158 P + L K QF Q Q EL L K R T+ A Sbjct: 165 LPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS--TWQNQKYQKELNLDKKRAERLTVLAR 222 Query: 159 VDGIISRVNIDQ 170 ++ + +++ Sbjct: 223 INRYENLSRVEK 234 Score = 37.5 bits (87), Expect = 6e-05 Identities = 35/194 (18%), Positives = 65/194 (33%), Gaps = 25/194 (12%) Query: 92 TDYQLDVDNATARFSVVDSQYRRSRPLVD--KGLLAKSQFDEIA-AQRQIALAELELAKL 148 + ++ ++ ++S+ ++ L D++ I L LELAK Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKN 321 Query: 149 --RLSFTTLKAPVDGIISRVNI-DQFENVQVGQHIVNIHSLDR---VEVLIQ--LPDRLY 200 R + ++APV + ++ + + V + ++ I D V L+Q + Sbjct: 322 EERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFIN 381 Query: 201 VKQPPTEERLTAINAVVRVPSGNEYKATVKEFT--TEPDPTTGT-FTVTLSLPMP----- 252 V Q ++ A VK D G F V +S+ Sbjct: 382 VGQ-NAIIKVEAFPY----TRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTG 436 Query: 253 -KEEYILDGMAVEV 265 K + GMAV Sbjct: 437 NKNIPLSSGMAVTA 450
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 513 bits (1323), Expect = e-167 Identities = 223/1053 (21%), Positives = 442/1053 (41%), Gaps = 64/1053 (6%) Query: 17 IAAYFIRNRVISWMVSLIFLIGGIAAFFGLGRLEDPAFTIKDAMVVTSYPGATPQQVEEE 76 +A +FIR + +W++++I ++ G A L + P V +YPGA Q V++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 77 VTYPLEKAIQQLTYVDEVNSISNR-GLSQITVTMKNNYGPDDLPQIWDELRRKVNDLKVT 135 VT +E+ + + + ++S S+ G IT+T ++ PD +++ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQV---QVQNKLQLATPL 117 Query: 136 LPPGVNEPQV-IDDFGDVYGILLAVTGDGYSY--KELLDYVD-YLRRELELVDGVSKVSV 191 LP V + + ++ Y ++ D ++ DYV ++ L ++GV V + Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 192 SGQQQEQVFIEVSMKKLSSIGLSPNTVFNLLSTQNIVSDAGAIRIGDEYI-------RIQ 244 G Q + I + L+ L+P V N L QN AG + G + I Sbjct: 178 FGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQL-GGTPALPGQQLNASII 235 Query: 245 PTGEFQSVDELGDLLITESGAQGLIFLKDVAEIKRGYVEVPSNIINFNGSLALNVGVSFA 304 F++ +E G + + + ++ LKDVA ++ G E + I NG A +G+ A Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELG-GENYNVIARINGKPAAGLGIKLA 294 Query: 305 QGVNVVEVGKAFDRRLAELKYQQPVGVEISEIYSQPKEVDKSVSGFVISLAQAVGIVIIV 364 G N ++ KA +LAEL+ P G+++ Y V S+ V +L +A+ +V +V Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 365 LLFFMG-LRSGLLIGLILLLTVLGTFIFMKYLAIDLQRISLGALVIALGMLVDNAIVVVE 423 + F+ +R+ L+ + + + +LGTF + + +++ +V+A+G+LVD+AIVVVE Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 424 GILIGTQKGRTRLQAAT-DIVTQTKWPLLGATVIAVTAFAPIGLSEDSTGEYCGTLFTVL 482 + + + + AT ++Q + L+G ++ F P+ STG + Sbjct: 415 NVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 483 LISLMLSWFTAISLTPFFADIFFKGQKIKQGEGEENDPYNGIIFVAYKKFLEF------- 535 + ++ LS A+ LTP K + E + G + + Sbjct: 475 VSAMALSVLVALILTPALCATLLKP--VSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGK 532 Query: 536 CMRRAWLTVVVLIVGLGASVYGFTLVKQSFFPSSTTPIFQLDVWLPEGTDIRATNDKLKE 595 + +++ + + V F + SF P +F + LP G T L + Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 596 LESWL--AEQEHVDHITTTAGKGLQRFMLTYAPEKSYAAYGEIT-----TRVDNYEALAP 648 + + E+ +V+ + T G +++ + A ++ R + + Sbjct: 593 VTDYYLKNEKANVESVFTVNG-------FSFSGQAQNAGMAFVSLKPWEERNGDENSAEA 645 Query: 649 LMARFRDHLKANYPEINYKLK---QIELGPGGGAKIE-ARIIGSDPTVLRTIAAQVMDIM 704 ++ R + L +ELG G E G L Q++ + Sbjct: 646 VIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMA 705 Query: 705 YADPSA-TNIRHDWRERTQVLEPQFNESQARRYGITKSDVDDFLSMSFSGMTIGLYRDGT 763 P++ ++R + E T + + ++ +A+ G++ SD++ +S + G + + D Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 764 TLMPIVARLPEDERIDIRNIEGMKIWSPAQSEFIPLQQVTMGYDMRWED--PIIVRKNRK 821 + + + R+ +++ + + S A E +P T W P + R N Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVRS-ANGEMVPFSAFT---TSHWVYGSPRLERYNGL 821 Query: 822 RMLTVMADPDILGEETASTLQKRLQPQIEAIQMPPGYSLEWGGEYESSGDAQESLFTTMP 881 + + + S+ + A ++P G +W G + + Sbjct: 822 PSMEIQGEA----APGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVA 877 Query: 882 MGYLFMFLITVFLFNSIKEPLIVWLTVPLALIGVTTGLLALNTPFGFMALLGFLSLSGMV 941 + ++ +FL L+ S P+ V L VPL ++GV N ++G L+ G+ Sbjct: 878 ISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLS 937 Query: 942 LKNGIVLLDQI-EIEMKSGKEAYDAVVDAAVSRVRPVCMAAITTILGMIPLLPDI----- 995 KN I++++ ++ K GK +A + A R+RP+ M ++ ILG++PL Sbjct: 938 AKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSG 997 Query: 996 FFKPMAVTIMFGLGFATILTLIVVPVLYRLFHK 1028 + + +M G+ AT+L + VPV + + + Sbjct: 998 AQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 31.4 bits (71), Expect = 0.007 Identities = 23/109 (21%), Positives = 42/109 (38%), Gaps = 13/109 (11%) Query: 51 STSSNAFGDYKVEFESSSMPLYVVAQQGSYTDPLTKEIVSSSVGKTLRLEGVVNFSEGSN 110 S+++ G + + + M VVA+ GS + ++I+ VG +RL + Sbjct: 241 SSTTQYMGVLRDKLSTVDMD--VVAEVGSLRLSV-RDILGLRVGDIIRL----------H 287 Query: 111 QKLMLTPLTNIVSGFAKYKIAGGVSGPDAVSQALDSINGMYGFDVNETT 159 + P + K+ GV G +Q L+ I D E + Sbjct: 288 DTHVGDPFVLSIGNRKKFLCQPGVVGKKIAAQILERIESTSQEDFEELS 336
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 55.3 bits (133), Expect = 8e-10 Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 16/125 (12%) Query: 604 KIEFAFNSREKELKDHAS-IFKQLAASLANVLEDEPNLRVEIEGHACQVGTEKANMQVSA 662 + F FN LK QL + L+N+ D + V + G+ ++G++ N +S Sbjct: 220 DVLFNFNK--ATLKPEGQAALDQLYSQLSNL--DPKDGSVVVLGYTDRIGSDAYNQGLSE 275 Query: 663 ERAEYAKKLLMKEFPVFDGRVSIAAFGESKPV------YVPKQGEKVDRNNPNLRQNRRV 716 RA+ L+ + + ++S GES PV V ++ +D L +RRV Sbjct: 276 RRAQSVVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALID----CLAPDRRV 330 Query: 717 VIRIY 721 I + Sbjct: 331 EIEVK 335
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 396 bits (1019), Expect = e-135 Identities = 133/369 (36%), Positives = 195/369 (52%), Gaps = 14/369 (3%) Query: 184 KSLSADNQALVRENTQLKKRTQKAYQGP--IAESEEMLNVLNRLDKVLSLPVDVLLRGET 241 + + +AL + K + G + S M + L +++ + +++ GE+ Sbjct: 110 ELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGES 169 Query: 242 GAGKEVIAKYIHENSNRSEQPLIVQNCAAIPEQLLESELFGHKKGSFTGADKDKVGLFEA 301 G GKE++A+ +H+ R P + N AAIP L+ESELFGH+KG+FTGA G FE Sbjct: 170 GTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQ 229 Query: 302 ANGGTLFLDEIGDMPMLLQAKLLRVLQERKVRPIGTSKEIEVDVRVIAATHCNLMQQIKD 361 A GGTLFLDEIGDMPM Q +LLRVLQ+ + +G I DVR++AAT+ +L Q I Sbjct: 230 AEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQ 289 Query: 362 GGFRADLFYRLNVFPITLPPLRARKSDIIPLAEHFVQHTTNTLGLPQAPGLSANVRKQLL 421 G FR DL+YRLNV P+ LPPLR R DI L HFVQ GL + + Sbjct: 290 GLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQ-AEKEGLD-VKRFDQEALELMK 347 Query: 422 AYQYPGNVRELKNIIERSVLLSDFETITHIEFGEQIPEDVPNIDMKAASPTPDQ------ 475 A+ +PGNVREL+N++ R L + IT ++ ++P+ ++ A+ Sbjct: 348 AHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQA 407 Query: 476 -PAYERQAQADLEDA---SKSLKDVVSQYERTVIIDCLNACNWHTKKAAEQLALPMSTLN 531 RQ A DA S V+++ E +I+ L A + KAA+ L L +TL Sbjct: 408 VEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLR 467 Query: 532 HKMKKYDIS 540 K+++ +S Sbjct: 468 KKIRELGVS 476
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.6 bits (82), Expect = 9e-04 Identities = 58/327 (17%), Positives = 104/327 (31%), Gaps = 64/327 (19%) Query: 579 LQDEAETTLKLKESLTQSIKGQEYAIDALSEGIQTAK---AGLGNPDAPTGVFLLVGPSG 635 + A K + S + + S +Q A L D ++ G SG Sbjct: 114 IIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL---MITGESG 170 Query: 636 VGKTETARAIADQMFGGERFMTTINMSEFQEKHTVSRLIGSPPGYVGYGEGGMLTEAVRQ 695 GK ARA+ D INM+ S L G E G T A + Sbjct: 171 TGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH--------EKGAFTGAQTR 222 Query: 696 RPYSV-------VLLDEVEKADPEVLNLFYQVFDKGTLND-GEGRTIDFKNTLIIMTSNL 747 + LDE+ + +V +G G I + I+ Sbjct: 223 STGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRS-DVRIV----A 277 Query: 748 ATHE-IESLVHQSKEIDANIIAEAIRPTLNQHFKPALLARMSVLPFV--PLSD--EAMTE 802 AT++ ++ ++Q F+ L R++V+P PL D E + + Sbjct: 278 ATNKDLKQSINQ------------------GLFREDLYYRLNVVPLRLPPLRDRAEDIPD 319 Query: 803 IIHHKLNKVSQRLHSHHKLSLSYEESLVEFVL-----GNCR-----LAETGARNIDAVIN 852 ++ H + Q+ +++ +E + GN R + A VI Sbjct: 320 LVRHFV----QQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVIT 375 Query: 853 RQLLPQLSTQLLVHDKDDSHTQITVSV 879 R+++ + + + S+ Sbjct: 376 REIIENELRSEIPDSPIEKAAARSGSL 402
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 40.1 bits (93), Expect = 4e-05 Identities = 35/141 (24%), Positives = 51/141 (36%), Gaps = 9/141 (6%) Query: 555 TETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDI 614 T+T T+T TQ +N SDL G T+ G N L G S T + Sbjct: 503 TQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTA 562 Query: 615 GADDNQT--VGGNLTVSVKGNTSYKAD-------GATQIISGDKIVLKTGGSSLVMNSDG 665 G QT G +LT + +D G+TQ S + GS+ Sbjct: 563 GYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQS 622 Query: 666 SIKLSGSSITIEGSDKVVVKG 686 + S + G+D ++ G Sbjct: 623 VLTTGYGSTSTAGADSSLIAG 643 Score = 39.0 bits (90), Expect = 7e-05 Identities = 28/125 (22%), Positives = 47/125 (37%) Query: 555 TETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDI 614 T+T + +T TQ + NSDL G T+ G + L G S T G + Sbjct: 839 TQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSLIAGYGSTQTAGYNSILTA 898 Query: 615 GADDNQTVGGNLTVSVKGNTSYKADGATQIISGDKIVLKTGGSSLVMNSDGSIKLSGSSI 674 G QT N ++ ++ A + +I+G S +M GS + + Sbjct: 899 GYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTLMAGYGSSQTAREQS 958 Query: 675 TIEGS 679 ++ Sbjct: 959 SLTAG 963 Score = 38.6 bits (89), Expect = 9e-05 Identities = 38/160 (23%), Positives = 58/160 (36%), Gaps = 16/160 (10%) Query: 536 GDHKETIDGHKTTQVNSTFTETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDD 595 GD I G+ +TQ T +D ++T TQ + SDL G T+ G Sbjct: 443 GDDSSLIAGYGSTQ-------TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESS 495 Query: 596 LDVGENSNLTVGASKSSDIGADDNQT--VGGNLTVSVKGNTSYKAD-------GATQIIS 646 L G S T G + G QT +L ++ A+ G+TQ S Sbjct: 496 LIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTAS 555 Query: 647 GDKIVLKTGGSSLVMNSDGSIKLSGSSITIEGSDKVVVKG 686 + ++ GS+ + S GSD ++ G Sbjct: 556 YNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAG 595 Score = 38.2 bits (88), Expect = 1e-04 Identities = 38/160 (23%), Positives = 56/160 (35%), Gaps = 16/160 (10%) Query: 536 GDHKETIDGHKTTQVNSTFTETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDD 595 GD I G+ +TQ T +D ++T TQ + SDL G T G + Sbjct: 347 GDDSSLIAGYGSTQ-------TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSS 399 Query: 596 LDVGENSNLTVGASKSSDIGADDNQT--VGGNLTVSVKGNTSYKAD-------GATQIIS 646 L G S T G + G QT G +LT + D G+TQ Sbjct: 400 LIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAG 459 Query: 647 GDKIVLKTGGSSLVMNSDGSIKLSGSSITIEGSDKVVVKG 686 D + GS+ + S + G + ++ G Sbjct: 460 EDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAG 499 Score = 37.8 bits (87), Expect = 2e-04 Identities = 38/164 (23%), Positives = 59/164 (35%), Gaps = 14/164 (8%) Query: 526 VARHQTNEVHGDHKETIDGHKTTQV---NSTF------TETVEQDVTVTYNANETQYVKN 576 +A + + E GD I G+ +T +ST T+T ++ + TQ Sbjct: 177 IAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQMAGYGSTQTGMK 236 Query: 577 NSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDIGADDNQTVGGNLTVSVKGNTSY 636 SDL G T G + L G S T G S G QT ++ ++ Sbjct: 237 GSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTG 296 Query: 637 KADGATQIISGDKIVLKTGGSSLVMNSDGSIKLSGSSITIEGSD 680 A + +I+G G S GS + + +GSD Sbjct: 297 TAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQ-----KGSD 335 Score = 37.4 bits (86), Expect = 2e-04 Identities = 38/142 (26%), Positives = 56/142 (39%), Gaps = 11/142 (7%) Query: 555 TETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDI 614 T+T ++T TQ + S L G T+ G + L G S T G + Sbjct: 599 TQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTA 658 Query: 615 GADDNQTV--GGNLTVSVKGNTSYKAD-------GATQIISGDKIVLKTGGSSLVMNSDG 665 G QT G +LT ++ AD G+TQ +G +L G S +G Sbjct: 659 GYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQ-TAGYNSILTAGYGSTQTAQEG 717 Query: 666 SIKLSG-SSITIEGSDKVVVKG 686 S SG S + G+D ++ G Sbjct: 718 SDLTSGYGSTSTAGADSSLIAG 739 Score = 37.0 bits (85), Expect = 3e-04 Identities = 28/122 (22%), Positives = 47/122 (38%) Query: 555 TETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDI 614 T+T + +T TQ + NSDL G T+ G L G S T + Sbjct: 887 TQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTLMA 946 Query: 615 GADDNQTVGGNLTVSVKGNTSYKADGATQIISGDKIVLKTGGSSLVMNSDGSIKLSGSSI 674 G +QT +++ ++ A + +I+G G S + GS + + S Sbjct: 947 GYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEHSS 1006 Query: 675 TI 676 T+ Sbjct: 1007 TL 1008 Score = 37.0 bits (85), Expect = 3e-04 Identities = 34/141 (24%), Positives = 50/141 (35%), Gaps = 9/141 (6%) Query: 555 TETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDI 614 T+T +D ++T TQ + SDL G T G + L G S T G + Sbjct: 263 TQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTA 322 Query: 615 GADDNQT--VGGNLTVSVKGNTSYKAD-------GATQIISGDKIVLKTGGSSLVMNSDG 665 G QT G +LT + D G+TQ D + GS+ Sbjct: 323 GYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGS 382 Query: 666 SIKLSGSSITIEGSDKVVVKG 686 + S G+D ++ G Sbjct: 383 DLTAGYGSTGTAGADSSLIAG 403 Score = 36.7 bits (84), Expect = 4e-04 Identities = 35/141 (24%), Positives = 48/141 (34%), Gaps = 9/141 (6%) Query: 555 TETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDI 614 T+T ++ T T TQ + SDL G T G + L G S T G S Sbjct: 311 TQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTA 370 Query: 615 GADDNQT--VGGNLTVSVKGNTSYKAD-------GATQIISGDKIVLKTGGSSLVMNSDG 665 G QT G +LT + AD G+TQ + GS+ Sbjct: 371 GYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGS 430 Query: 666 SIKLSGSSITIEGSDKVVVKG 686 + S G D ++ G Sbjct: 431 DLTAGYGSTGTAGDDSSLIAG 451 Score = 35.9 bits (82), Expect = 7e-04 Identities = 36/142 (25%), Positives = 52/142 (36%), Gaps = 11/142 (7%) Query: 555 TETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDI 614 T+T + +T TQ + SDL G T G + + G S T S Sbjct: 551 TQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTA 610 Query: 615 GADDNQT--VGGNLTVSVKGNTSYKAD-------GATQIISGDKIVLKTGGSSLVMNSDG 665 G QT LT ++ AD G+TQ + I L G S +G Sbjct: 611 GYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSI-LTAGYGSTQTAQEG 669 Query: 666 SIKLSG-SSITIEGSDKVVVKG 686 S +G S + G+D ++ G Sbjct: 670 SDLTAGYGSTSTAGADSSLIAG 691 Score = 35.9 bits (82), Expect = 7e-04 Identities = 32/141 (22%), Positives = 52/141 (36%), Gaps = 9/141 (6%) Query: 555 TETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDI 614 T+T ++ T T TQ + SDL G T G + L G S T G S Sbjct: 407 TQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTA 466 Query: 615 GADDNQT--VGGNLTVSVKGNTSYKAD-------GATQIISGDKIVLKTGGSSLVMNSDG 665 G QT G +LT ++ + G+TQ + GS+ ++ Sbjct: 467 GYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNES 526 Query: 666 SIKLSGSSITIEGSDKVVVKG 686 + S + G++ ++ G Sbjct: 527 DLITGYGSTSTAGANSSLIAG 547 Score = 34.3 bits (78), Expect = 0.002 Identities = 32/141 (22%), Positives = 50/141 (35%), Gaps = 9/141 (6%) Query: 555 TETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDI 614 T+T ++T TQ + S L G T+ G + L G S T G Sbjct: 743 TQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTA 802 Query: 615 GADDNQTV--GGNLTVSVKGNTSYKAD-------GATQIISGDKIVLKTGGSSLVMNSDG 665 G QT +LT ++ AD G+TQ + I+ GS+ + Sbjct: 803 GYGSTQTAQERSDLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENS 862 Query: 666 SIKLSGSSITIEGSDKVVVKG 686 + S + G D ++ G Sbjct: 863 DLTTGYGSTSTAGYDSSLIAG 883 Score = 34.3 bits (78), Expect = 0.002 Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 16/151 (10%) Query: 552 STFTETVEQDVTVTYNANE--------------TQYVKNNSDLEIGDNRTTKIGKNDDLD 597 S+ +T Y +N+ TQ N S L G + G L Sbjct: 1062 SSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGYRSTLI 1121 Query: 598 VGENSNLTVGASKSSDIGADDNQTVGGNLTVSVKGNTSYKADG-ATQIISGDKIVLKTGG 656 G +S G GAD QT G+ + + GN SY G +++ +G+ +L G Sbjct: 1122 SGADSVQMAGERGKLIAGADSTQT-AGDRSKLLAGNNSYLTAGDRSKLTAGNDCILMAGD 1180 Query: 657 SSLVMNSDGSIKLSGSSITIEGSDKVVVKGG 687 S + SI +G + GS+ + G Sbjct: 1181 RSKLTAGINSILTAGCRSKLIGSNGSTLTAG 1211 Score = 33.2 bits (75), Expect = 0.005 Identities = 28/118 (23%), Positives = 43/118 (36%) Query: 555 TETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDI 614 T T D ++ TQ +S L G T + L G S T GA S Sbjct: 583 TGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIA 642 Query: 615 GADDNQTVGGNLTVSVKGNTSYKADGATQIISGDKIVLKTGGSSLVMNSDGSIKLSGS 672 G QT G N ++ ++ A + + +G G S ++ GS + +G Sbjct: 643 GYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGY 700 Score = 32.8 bits (74), Expect = 0.005 Identities = 34/152 (22%), Positives = 59/152 (38%), Gaps = 5/152 (3%) Query: 525 KVARHQTNEVHGDHKETIDGHKTTQV---NSTFTETVEQDVTVTYNANETQYVKNNSDLE 581 + AR Q+ G + G ++ + ST T +T Y + TQ + SDL Sbjct: 760 QTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGS--TQTAQERSDLT 817 Query: 582 IGDNRTTKIGKNDDLDVGENSNLTVGASKSSDIGADDNQTVGGNLTVSVKGNTSYKADGA 641 G T+ G + L G S T G + G QT N ++ ++ A Sbjct: 818 TGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYD 877 Query: 642 TQIISGDKIVLKTGGSSLVMNSDGSIKLSGSS 673 + +I+G G +S++ GS + + + Sbjct: 878 SSLIAGYGSTQTAGYNSILTAGYGSTQTAQEN 909 Score = 32.0 bits (72), Expect = 0.009 Identities = 41/177 (23%), Positives = 63/177 (35%), Gaps = 17/177 (9%) Query: 519 GQDEFLKVARHQTNEVHGDHKETIDGHKTTQVNSTFTETVEQDVTVTYNANETQYVKNNS 578 G D + +A + + + H G+ +TQ T + +T Y + T +S Sbjct: 587 GSDSSI-IAGYGSTQTASYHSSLTAGYGSTQ-----TAREQSVLTTGYGSTST--AGADS 638 Query: 579 DLEIGDNRTTKIGKNDDLDVG--------ENSNLTVGASKSSDIGADDNQTVGGNLTVSV 630 L G T G N L G E S+LT G +S GAD + G T + Sbjct: 639 SLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTA 698 Query: 631 KGNTSYKAD-GATQIISGDKIVLKTGGSSLVMNSDGSIKLSGSSITIEGSDKVVVKG 686 N+ A G+TQ + GS+ +D S+ S + G Sbjct: 699 GYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAG 755 Score = 31.3 bits (70), Expect = 0.019 Identities = 33/141 (23%), Positives = 49/141 (34%), Gaps = 9/141 (6%) Query: 555 TETVEQDVTVTYNANETQYVKNNSDLEIGDNRTTKIGKNDDLDVGENSNLTVGASKSSDI 614 T+T + +T TQ + SDL G T+ G + L G S T S Sbjct: 695 TQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTA 754 Query: 615 GADDNQTV--GGNLTVSVKGNTSYKAD-------GATQIISGDKIVLKTGGSSLVMNSDG 665 G QT LT ++ AD G+TQ I+ GS+ Sbjct: 755 GYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERS 814 Query: 666 SIKLSGSSITIEGSDKVVVKG 686 + S + G+D ++ G Sbjct: 815 DLTTGYGSTSTAGADSSLIAG 835 Score = 30.5 bits (68), Expect = 0.032 Identities = 37/160 (23%), Positives = 59/160 (36%), Gaps = 18/160 (11%) Query: 519 GQDEFLKVARHQTNEVHGDHKETIDGHKTTQV---NSTFT------ETVEQDVTVTYNAN 569 Q+ + + G I G+ +TQ ST +T + ++T Sbjct: 906 AQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTLMAGYGSSQTAREQSSLTAGYG 965 Query: 570 ETQYVKNNSDLEIGDNRTTKIGKNDDLDVG--------ENSNLTVGASKSSDIGADDNQT 621 T +S L G T G L G +S LT G ++ GAD + Sbjct: 966 STSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEHSSTLTAGYGSTATAGADSSLI 1025 Query: 622 VGGNLTVSVKGNTSYKADGATQIISGDKIVLKTG-GSSLV 660 G +++ + A + +ISG + VL G GSSL+ Sbjct: 1026 AGYGSSLTSGIRSFLTAGYGSTLISGLRSVLTAGYGSSLI 1065
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 83.4 bits (206), Expect = 3e-21 Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 11/122 (9%) Query: 78 MQVRVLFANDSDEINPVFRRQIRELSDFLKDY--PTTSIELQGYASKTGGSKHNQDLSER 135 ++ VLF + + P + + +L L + S+ + GY + G +NQ LSER Sbjct: 217 LKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSER 276 Query: 136 RAKNVRDALLSYGIEPNRVRIIGFGDTH-LAEQGTDQVSH--------ALNRRVTASVVG 186 RA++V D L+S GI +++ G G+++ + D V A +RRV V G Sbjct: 277 RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKG 336 Query: 187 YK 188 K Sbjct: 337 IK 338
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 251 bits (642), Expect = 2e-87 Identities = 98/217 (45%), Positives = 145/217 (66%), Gaps = 7/217 (3%) Query: 6 DELNLIVSLALLALIPFIAMMATSFVKLAVVFSLLRNALGVQQIPPNMALYGLAIILSIF 65 ++++LI LA L+PFI T FVK ++VF ++RNALG+QQIP NM L G+A++LS+F Sbjct: 3 NDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMF 62 Query: 66 IMAPVGFETYDYVKQHDISLEDSASVEGLIESGLQPYREFLKKHIRETEAIFFTDAARTL 125 +M P+ + Y Y + D++ D +S+ ++ GL YR++L K+ FF +A Sbjct: 63 VMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKR 122 Query: 126 WP-------QKYVDRLESDSLLLLLPAFTVSELTRAFEIGFLLYLPFIAIDLIVSNILLA 178 ++ D +E S+ LLPA+ +SE+ AF+IGF LYLPF+ +DL+VS++LLA Sbjct: 123 QYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVLLA 182 Query: 179 MGMMMVSPMTISLPFKLLLFVLLDGWTKLTHGLVLSY 215 +GMMM+SP+TIS P KL+LFV LDGWT L+ GL+L Y Sbjct: 183 LGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQY 219
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 62.1 bits (151), Expect = 1e-16 Identities = 31/80 (38%), Positives = 48/80 (60%) Query: 5 EIIHFTTQALTLVLFLSLPPILVAALVGTLVSLIQALTQVQEQTLGFVVKLIAVIITLFI 64 +++ +AL LVL LS P +VA ++G LV L Q +TQ+QEQTL F +KL+ V + LF+ Sbjct: 3 DLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFL 62 Query: 65 TTQWLGAELHAFASLALDKI 84 + W G L ++ + Sbjct: 63 LSGWYGEVLLSYGRQVIFLA 82
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 156 bits (395), Expect = 8e-49 Identities = 53/240 (22%), Positives = 103/240 (42%), Gaps = 5/240 (2%) Query: 10 LFLYSLTLPRLMACFIFLPILSKQMLGGAMIRNGVLCSLALFIFPVVNEQALPAETDGLW 69 L LY L R++A PILS++ + ++ G+ + I P + +P + Sbjct: 13 LNLYFWPLLRVLALISTAPILSERSVPK-RVKLGLAMMITFAIAPSLPANDVPVFSFFAL 71 Query: 70 LIVILGKEVLLGMLIGFVAAIPFWAIEATGFLVDNQRGAAMASMFNPTLGSQSTPTAVLL 129 + + +++L+G+ +GF F A+ G ++ Q G + A+ +P A ++ Sbjct: 72 WLAV--QQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIM 129 Query: 130 TQTLITLFFSGGGFVAFIYALFKSYTTWPILGFFPMVTDAWVSFFYDQFQQLMWLGVLMS 189 + LF + G + I L ++ T PI G + G++++ Sbjct: 130 DMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPL--NSNAFLALTKAGSLIFLNGLMLA 187 Query: 190 APLVLAMFLAEFGLALISRFAPQLNVFFLAMPIKSAIASVLLIVYLGLMMDHFEALFYGI 249 PL+ + L L++R APQL++F + P+ + L+ + L+ E LF I Sbjct: 188 LPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEI 247
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 416 bits (1072), Expect = e-148 Identities = 217/347 (62%), Positives = 281/347 (80%) Query: 1 MSGEKTEQPTAKKLRDARKKGQVAKSQEIVSSALILALIAVLFAFADYYMSHISALLLLP 60 MSGEKTEQPT KK+RDARKKGQVAKS+E+VS+ALI+AL A+L +DYY H S L+L+P Sbjct: 1 MSGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIP 60 Query: 61 SELAYQGFQDALIDVAIAIAKEIAYLLAPIILVAALIAIFSNMGQFGFLFSGESIKPDIK 120 +E +Y F AL V + E YL P++ VAAL+AI S++ Q+GFL SGE+IKPDIK Sbjct: 61 AEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIK 120 Query: 121 KINPVEGAKRIFSLKSVIEFIKSILKVSLLSCIIWVTLRGNINTLMQIPTCGLECVPAVT 180 KINP+EGAKRIFS+KS++EF+KSILKV LLS +IW+ ++GN+ TL+Q+PTCG+EC+ + Sbjct: 121 KINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLL 180 Query: 181 GVMIKQLMIISSVGFVVIAAADFAYQKFDHTKKLKMSKDEVKREYKEMEGSPEIKSKRRQ 240 G +++QLM+I +VGFVVI+ AD+A++ + + K+LKMSKDE+KREYKEMEGSPEIKSKRRQ Sbjct: 181 GQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQ 240 Query: 241 LHQELQASNQRENVKRSNVLVTNPTHIAVGLYYKKGETPLPVITLMETDAMAKRMIAIAR 300 HQE+Q+ N RENVKRS+V+V NPTHIA+G+ YK+GETPLP++T TDA + + IA Sbjct: 241 FHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAE 300 Query: 301 EEGVPVMQKVPLARALYADGNVDQYIPSELIEATAEVLRWLASLESD 347 EEGVP++Q++PLARALY D VD YIP+E IEATAEVLRWL + Sbjct: 301 EEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIE 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.3 bits (198), Expect = 1e-19 Identities = 32/140 (22%), Positives = 60/140 (42%), Gaps = 6/140 (4%) Query: 4 ATRVMIIEDDIAIAELHHKYLSQLAGLDVVGIATTRLEAEMQLEVLKPDLLLMDVYLPDG 63 +++ +DD AI + ++ LS+ AG DV + + DL++ DV +PD Sbjct: 3 GATILVADDDAAIRTVLNQALSR-AGYDVRITSNAA-TLWRWIAAGDGDLVVTDVVMPDE 60 Query: 64 TGLEILNTLRSNNQTCDVILITAARDVDTLQQAMRGGVVDYLLKPV----MFPRLETALK 119 ++L ++ V++++A T +A G DYL KP + + AL Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 KYITQRQQLDVAKSLDQGLV 139 + + +L+ LV Sbjct: 121 EPKRRPSKLEDDSQDGMPLV 140
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.006 Identities = 33/234 (14%), Positives = 74/234 (31%), Gaps = 56/234 (23%) Query: 320 EQLSQTKEYADL--LRSQTHEH--RNKLNTISGLVQMGELEAVQKLIGQETAHYQAMIEF 375 +++ + A L L++Q + H N LN I L+ +A + L ++ E Sbjct: 152 WKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREML--------TSLSEL 203 Query: 376 LRDTIKDPLIAGMLLGK----------TERAR---ELGLQLVVEEGSRLEPLTEWLNSED 422 +R +++ + L + L + + ++ + Sbjct: 204 MRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINP--------AIMDVQV 255 Query: 423 LVTILGNLIDNAFDATLSVIRDESNVASERRNIEVSVSDYGNEVILEVSDHGCGLPENIE 482 ++ L++N ++ + I + + V LEV + G +N Sbjct: 256 PPMLVQTLVENGIKHGIAQLPQGG-------KILLKGTKDNGTVTLEVENTGSLALKN-- 306 Query: 483 PQTLFKKGISTKSRQNRGVGLHLVNQLATRYHG--HVEMLPNTGHGTRITVYLP 534 ++++ G GL V + +G L V +P Sbjct: 307 ------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 29.8 bits (67), Expect = 0.025 Identities = 25/171 (14%), Positives = 61/171 (35%), Gaps = 37/171 (21%) Query: 186 VEQGLKKHRDFAIKLEEQG-QIARVERLQAEA--------------SLDKAKVETR---- 226 +E ++H FA L+ +I +E L +E + +A+++T Sbjct: 48 LEVARQEHEVFASILKNNLVEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTIN 107 Query: 227 ------KAASDLSIAQAALGKLLAQE--------DSVEPAETLFVNDNLPPLSAFIDQTL 272 + + ++ + ++ +E D + LF+ D +P + D Sbjct: 108 LLKDYFSSLTIDNMISKMISGVVTEELKNYTSSLDDLVNGANLFIIDPMPNVLFTRDPFA 167 Query: 273 LTYPGLDI--LDAKHKQASSLIKAEKGKYYPEVYLYGDYSLYEDDSLASQM 321 G+ I + K +Q ++ KY+P + ++ + + + Sbjct: 168 SIGNGVTINKMFTKVRQRETIFAEYIFKYHPV--YKENVPIWLNRWEEASL 216
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.0 bits (96), Expect = 4e-06 Identities = 18/132 (13%), Positives = 45/132 (34%), Gaps = 9/132 (6%) Query: 48 ISSKVPGRIDEVMVRKGDDVEKGQLIFTLHSPEIEAKLEQAKAGEKAADALAQEAEKGAR 107 I + E++V++G+ V KG ++ L + EA + ++ A + +R Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 108 EQQIQAAKDQWLKAKAAADLMEKTYNRVNNLYKDGVVAEQKRDEALTQWQASKYTESAAF 167 ++ + L + + + ++ + E + WQ KY + Sbjct: 159 SIELNKLPELKLPDEPYFQNVSE---------EEVLRLTSLIKEQFSTWQNQKYQKELNL 209 Query: 168 QMYEMAKEGARS 179 + + Sbjct: 210 DKKRAERLTVLA 221
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.8 bits (80), Expect = 0.001 Identities = 31/232 (13%), Positives = 72/232 (31%), Gaps = 35/232 (15%) Query: 419 LLTVMATADQVDKNASEGQARAAASRDQLNVQVNEVNSLATAINEMSATAQEVANSAVQA 478 L + A AD + +S QAR +R Q L+ +I ++ + Sbjct: 127 LTALGAEADTLKTQSSLLQARLEQTRYQ---------ILSRSIELNKLPELKLPDEPYFQ 177 Query: 479 AAAASQVQSNSANGMSRMDNAASAVDNLASQVNDAQHQTQNLVASSTAIQGILSEIGGIA 538 + +V ++ + + ++ + + ++A I + Sbjct: 178 NVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLA---RINRYENLSRVEK 234 Query: 539 DQTNL---LALNAAIEAARAGEAGRGFAVVADEVRNLATRTQGSTEEIRAMLARLEQETQ 595 + + L AI E + E N + E+I + + ++E Q Sbjct: 235 SRLDDFSSLLHKQAIAKHAVLEQENKYV----EAVNELRVYKSQLEQIESEILSAKEEYQ 290 Query: 596 SIVVLMEQSQKQAVDTKEETQAAQLALAEINQAIEVINDMNNQIASAAEEQS 647 + + + + L ++ Q + I + ++A E Q Sbjct: 291 LVT---QLFKNE-------------ILDKLRQTTDNIGLLTLELAKNEERQQ 326
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.0 bits (213), Expect = 1e-21 Identities = 30/120 (25%), Positives = 58/120 (48%), Gaps = 1/120 (0%) Query: 3 RVLLVEDNREIAGMLFDYFECAGMQLDYADNGELGLKLAMDNAFDIILLDLMLPRMDGLT 62 +L+ +D+ I +L AG + N + D+++ D+++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 LCNKLRDAGNNTPVLMLTALDSRDDMLKGFQHGADDYLTKPFDLD-ILEARMTALIKRYR 121 L +++ A + PVL+++A ++ +K + GA DYL KPFDL ++ AL + R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 30.1 bits (67), Expect = 0.022 Identities = 46/146 (31%), Positives = 64/146 (43%), Gaps = 33/146 (22%) Query: 246 SDGYPHDELEACLQ----AGHHNNL--VKSIAQVDDG--KELALVMELIPNSYYNLGLPP 297 ++G+ ELEA AG H NL V +A V G KE AL+M+ + Sbjct: 169 AEGHLFAELEAYKHIYKTAGKHPNLANVHGMAVVPYGNRKEEALLMDEVDG----WRCSD 224 Query: 298 TLETCTRDTFPQGFTLTVEQVNS---------IVEQMVDVFNHLHDNKVCHGDLYAHNTL 348 TL T D++ QG ++NS I +++DV NHL V H D+ N + Sbjct: 225 TLRTLA-DSWKQG------KINSEAYWGTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVV 277 Query: 349 VNE-QGEMIFGDFGAASIYGYLSGEQ 373 + GE + D G S SGEQ Sbjct: 278 FDRASGEPVVIDLGLHS----RSGEQ 299
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 30.8 bits (69), Expect = 0.003 Identities = 32/137 (23%), Positives = 48/137 (35%), Gaps = 19/137 (13%) Query: 28 DALIENITKLVKGAKALDLPILWL----EQNPE-------------RLGPTAEPIREVL- 69 L NI KL L +P+++ QNP+ GP E I L Sbjct: 54 TELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELA 113 Query: 70 -ESTHLPITKYTFDGCKEATFKVAVENAKVDTWLVCGIESHICVYQTAVSLRQSGYRVEL 128 E L +TK+ + K + D ++ GI +HI TA + Sbjct: 114 PEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFF 173 Query: 129 VTDCVSSRTAANKALAL 145 V D V+ + +AL Sbjct: 174 VGDAVADFSLEKHQMAL 190
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 56.8 bits (137), Expect = 5e-11 Identities = 24/196 (12%), Positives = 63/196 (32%), Gaps = 9/196 (4%) Query: 1 MTADQKFKHWMRTLIVLFIVLFLYIIIADRHAPLTTEGRVQGYVV------QVAPEVSGK 54 T + + I+ F+V+ + + + G + ++ P + Sbjct: 50 ETPVSRRPRLVAYFIMGFLVIAFILSVL---GQVEIVATANGKLTHSGRSKEIKPIENSI 106 Query: 55 VTDVLIENNQSVQKGDVLFTIDDRKYKIALEQAELSLQSAYEKEATLYSQREAALANIAR 114 V +++++ +SV+KGDVL + + + + SL A ++ + N Sbjct: 107 VKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLP 166 Query: 115 AQATFDNAHREYTRLLTLSKQKVISQSTLDNAFAQNQVSRAALKAERQNLKVIEAQLGDQ 174 D + + + + + + Q L +R + A++ Sbjct: 167 ELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRY 226 Query: 175 KGQSTAVRIAKNGIEK 190 + S + + Sbjct: 227 ENLSRVEKSRLDDFSS 242 Score = 52.9 bits (127), Expect = 7e-10 Identities = 38/227 (16%), Positives = 80/227 (35%), Gaps = 29/227 (12%) Query: 64 QSVQKGDVLFTIDDRKYKIALEQAELSLQSAYEKEATLY---SQREAALANIARAQATFD 120 Q+V + +VL K + + Q + Y+KE L ++R LA I R + Sbjct: 177 QNVSEEEVLRLTSLIKEQFSTWQNQK-----YQKELNLDKKRAERLTVLARINRYENLSR 231 Query: 121 NAHREYTRLLTLSKQKVISQ----------STLDNAFAQNQVSRAALKAERQNLKVIEAQ 170 +L ++ I++ N + +++E + K Sbjct: 232 VEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL 291 Query: 171 LGDQKGQSTAVRIAKNG---------IEKAQLDLANTAVLAPSDGVVTNLQL-EVGTMAN 220 + ++ + + K + + + AP V L++ G + Sbjct: 292 VTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVT 351 Query: 221 TNMPLLTFVPTG-SLWVAADFREKSVANVDKTFHALVTFDANPGSVY 266 T L+ VP +L V A + K + ++ +A++ +A P + Y Sbjct: 352 TAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRY 398
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.4 bits (66), Expect = 0.024 Identities = 15/67 (22%), Positives = 31/67 (46%), Gaps = 4/67 (5%) Query: 173 MGWVVAMAAFIVFQV-ADLYDSLSAQASILIILTPMTLAGSLAMAKIRIIGTALGCIAGM 231 +VA++ +VF A LY+S S S+++++ P+ + G L A + + Sbjct: 872 APALVAISFVVVFLCLAALYESWSIPVSVMLVV-PLGIVGVLLAATLF--NQKNDVYFMV 928 Query: 232 AVQLILG 238 + +G Sbjct: 929 GLLTTIG 935
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 29.4 bits (66), Expect = 0.032 Identities = 12/85 (14%), Positives = 32/85 (37%), Gaps = 11/85 (12%) Query: 437 ENDPFNAYVADNKKGTLVNATVTAVDAKGATVEIAEGVE--GYIRASEVSRDRVEDASLI 494 + + N GT V T+ A + + V +A + +V + Sbjct: 73 DEGDPEIFKDYNGHGTHVAGTIAATENENGVVGVAPEADLLII---------KVLNKQGS 123 Query: 495 LSAGDVVEAKFTGVDRKNRVINLSI 519 +++ + +++K +I++S+ Sbjct: 124 GQYDWIIQGIYYAIEQKVDIISMSL 148
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 89.3 bits (221), Expect = 2e-23 Identities = 52/204 (25%), Positives = 95/204 (46%), Gaps = 4/204 (1%) Query: 9 ALEGKVILVTGAGNGIGRQAALSYAKHGATVILLGRNVKNLESIYDEIEAAGYPQAAIIP 68 +EGK+ +TGA GIG A + A GA + + N + LE + ++A A P Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF-P 63 Query: 69 LDLKGATKQNYIDMAETIEGQFGQLDGLLHNAGVLSALCPFEQINEEDFDDIMQINVKAE 128 D++ + + ++ IE + G +D L++ AGVL +++E+++ +N Sbjct: 64 ADVRDSAAID--EITARIEREMGPIDILVNVAGVLR-PGLIHSLSDEEWEATFSVNSTGV 120 Query: 129 VLMTQALLPVMRKSEAGRIIFTSSTVGHSGRAFWGPYAISKFAVEGMMQVLADELSDTPM 188 ++++ M +G I+ S R YA SK A + L EL++ + Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 189 RVNAINPGATRTRMREKAYPGEDA 212 R N ++PG+T T M+ + E+ Sbjct: 181 RCNIVSPGSTETDMQWSLWADENG 204
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 29.1 bits (65), Expect = 0.036 Identities = 24/94 (25%), Positives = 36/94 (38%), Gaps = 7/94 (7%) Query: 290 QLALHASFNWTD-WSSFEKLEAHLETAGTHMVKVENWEDN---YRFAVGATYQLQPKVAL 345 QL + TD + +L + A T D FA G Y + P++A Sbjct: 99 QLTAKLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIAT 158 Query: 346 RTGIAYDTSAVSDKNRTITIPETDRTWLSIGATY 379 R T+ + D + T P D LS+G +Y Sbjct: 159 RLEY-QWTNNIGDAHTIGTRP--DNGMLSLGVSY 189
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 269 bits (690), Expect = 2e-93 Identities = 101/249 (40%), Positives = 144/249 (57%), Gaps = 15/249 (6%) Query: 12 LLALGLVGCSSAPEEAVTSEGETNQTTSDVYDPLEGFNRTMWEINYEYLDPYLVRPVSIA 71 L LVGC+S+ DPLEGFNRTM+ N+ LDPY+VRPV++A Sbjct: 10 LGTTLLVGCASSGT-----------DQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVA 58 Query: 72 YVEYTPVPIRSGIANFLSNLDEPSSMVNNLLMGNGSKAVDHFNRFWINSTFGILGVFDIA 131 + +Y P P R+G++NF NL+EP+ MVN L G+ + + HF RF++N+ G+ G D+A Sbjct: 59 WRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVA 118 Query: 132 TAAGI--TKYDNKEFSSAVGHYGVGNGPYFMIPGYGPYTLR-EVTDTVDGMYLPLSYLNI 188 A + + F S +GHYGVG GPY +P YG +TLR + D D +Y LS+L Sbjct: 119 GMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTW 178 Query: 189 WAGLGKWALEGLEKRALLVPQEAQLDSSPDPYVLTRDVYIQRQNFKAEIDTVEEV-NPEE 247 +GKW LEG+E RA L+ + L S DPY++ R+ Y QR +F A ++ NP Sbjct: 179 PMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNA 238 Query: 248 EALLDEYLD 256 +A+ D+ D Sbjct: 239 QAIQDDLKD 247
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 29.0 bits (65), Expect = 0.036 Identities = 11/55 (20%), Positives = 21/55 (38%), Gaps = 4/55 (7%) Query: 313 NAVLIVSIHRADGSPMPVAAARYPLGSFPRTVVLDDGNAMMQGQKLSSLEKLIVR 367 +L+ + P+P A S +V D+G + G + K+ V+ Sbjct: 796 IKLLM--TLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSG--MPLAGKVQVK 846
>SECA#SecA protein signature. Length = 901 Score = 27.1 bits (60), Expect = 0.048 Identities = 9/16 (56%), Positives = 12/16 (75%) Query: 88 YLNELAGKGVKIIGMN 103 YLN L GKGV ++ +N Sbjct: 117 YLNALTGKGVHVVTVN 132
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 46.1 bits (109), Expect = 7e-08 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Query: 36 LLAQELSSVEPEPEPEPEPEPEPEPEPEPEPE-PEPEPEPEPEP 78 + +V+P PEP EPEPEPEP PEP E P +P+P+P Sbjct: 53 ADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP 96 Score = 44.6 bits (105), Expect = 2e-07 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 9/89 (10%) Query: 25 VEVTDLEHELDLLAQELSSVEPEPEPEPEPEPE---------PEPEPEPEPEPEPEPEPE 75 V DLE + VEPEPEPEP PEP P+P+P+P+P+P + + + Sbjct: 50 VTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQ 109 Query: 76 PEPELQMQYAESDSYQFRENYAPQLEAPN 104 P+ +++ + S A + Sbjct: 110 PKRDVKPVESRPASPFENTAPARLTSSTA 138 Score = 44.6 bits (105), Expect = 2e-07 Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 1/40 (2%) Query: 40 ELSSVEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPE 79 ++ V P P+ P P EPEPEPEP PEP E Sbjct: 46 SVTMVTPADLEPPQAVQPPPE-PVVEPEPEPEPIPEPPKE 84 Score = 43.4 bits (102), Expect = 5e-07 Identities = 17/54 (31%), Positives = 24/54 (44%), Gaps = 1/54 (1%) Query: 26 EVTDLEHELDLLAQELSSVEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPE 79 +V +L ++ + + P+ P P EPEPEPEP PEP E Sbjct: 34 QVIELPAPAQPISVTMVTPADLEPPQAVQPPPE-PVVEPEPEPEPIPEPPKEAP 86
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.6 bits (160), Expect = 8e-14 Identities = 32/165 (19%), Positives = 65/165 (39%), Gaps = 8/165 (4%) Query: 2 AIKVLVVDDSSFFRRRVSEIINSESRLEVIDVAVNGREAVEKAKALKPDVITMDIEMPVM 61 +LV DD + R +++ ++ + + N A D++ D+ MP Sbjct: 3 GATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGITAVREIMAASP-TPILMFSSLTHDGAKATLDALDAGALDFLPKKF--EDIARNRDEA 118 + + I A P P+L+ S+ + + A + GA D+LPK F ++ A Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSA--QNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 119 VSLLQQRVIQIASKRAFMRRPVARPAAATSSARPLASRTAAPAAS 163 ++ ++R ++ V R +AA + +R + Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGR-SAAMQEIYRVLARLMQTDLT 162
>PF06580#Sensor histidine kinase Length = 349 Score = 43.7 bits (103), Expect = 2e-06 Identities = 18/104 (17%), Positives = 41/104 (39%), Gaps = 18/104 (17%) Query: 449 ETDLDKNLVEALADPLI--HLVRNSVDHGIEMPEDRVKAGKSRTGKVILSASQEGDHIEL 506 E ++ +++ P++ LV N + HGI + GK++L +++ + L Sbjct: 243 ENQINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTL 294 Query: 507 AIVDDGGGMDPNKLRGIAVK--------RGMMDEDAAARLSDKE 542 + + G N + + +A +LS+K+ Sbjct: 295 EVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQ 338
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.7 bits (225), Expect = 1e-24 Identities = 34/121 (28%), Positives = 54/121 (44%), Gaps = 3/121 (2%) Query: 6 KILIVDDFSTMRRIVKNLLRDLGFNNTQEADDGLTALPMLKKGDFDFVVTDWNMPGMQGI 65 IL+ DD + +R ++ L G++ + T + GD D VVTD MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 DLLKHIRADAELKHLPVLMITAEAKREQIIEAAQAGVNGYIVKPFTAATLKEKLEKIFER 125 DLL I+ LPVL+++A+ I+A++ G Y+ KPF L + + Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 126 L 126 Sbjct: 122 P 122
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.048 Identities = 24/99 (24%), Positives = 36/99 (36%), Gaps = 26/99 (26%) Query: 219 VSGLMWQEVERREPLRAMLIKRLERMGVSPELADQMACYIPEDTKPAR--AWKALLSLVA 276 V W EV R L L+ L G +P+ Y P + + L+ VA Sbjct: 539 VKAQQWDEVPR---LEKWLVHVL---GKTPD------DYKPRRLRYLQLVGKYILMGHVA 586 Query: 277 DQINIPKQDILKRG----GVVALLGPTGVGKTTTVAKLA 311 +++ G V L G G+GK+T + L Sbjct: 587 R--------VMEPGCKFDYSVVLEGTGGIGKSTLINTLV 617
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 64.4 bits (156), Expect = 2e-14 Identities = 46/208 (22%), Positives = 99/208 (47%), Gaps = 7/208 (3%) Query: 47 SWVPNFDEPEEEQALELTEEQIELIKQG--AYQEGLYQGQEAGFKQGYDKGKEEGLQAGH 104 +W P+ P + + + + E + +I++ + ++ L Q Q +QGY G EG Q GH Sbjct: 9 TWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGH 68 Query: 105 AEGLELGKAEGVSAGQEFIQ-QQVEV---FMNLANQFAQPLELMNAQVEKQLVDMVLCLV 160 +G + G A+G+ G + QQ + L ++F L+ +++ + +L+ M L Sbjct: 69 KQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAA 128 Query: 161 KEVVHVEVQTNPQIILDTVKQSVEALPISGHPITLHLNPEDVAIIRSAYGEEDLDCRNWT 220 ++V+ + ++ ++Q ++ P+ L ++P+D+ + G L W Sbjct: 129 RQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT-LSLHGWR 187 Query: 221 LVSEPSLNRGDVQIEAGESSINYRMEER 248 L +P+L+ G ++ A E ++ + R Sbjct: 188 LRGDPTLHPGGCKVSADEGDLDASVATR 215
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 290 bits (743), Expect = 1e-98 Identities = 108/330 (32%), Positives = 199/330 (60%) Query: 20 DASTITGEEKAAILLLSLNEQDAAGIIRHLEPKQVQRVGSAMARAKDLSQEKVSAVHRTF 79 D S +TG++KAAILL+S+ + ++ + ++L ++++ + +A+ + ++ E V F Sbjct: 11 DVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEF 70 Query: 80 LEDIQKYTNIGMGSEDFMRNALVAALGEDKANNLVDQILLGTGSKGLDSLKWMDPRQVAS 139 E + I G D+ R L +LG KA ++++ + S+ + ++ DP + + Sbjct: 71 KELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILN 130 Query: 140 IIVNEHPQIQTIVLSYLEADQSAEILSQFPERVRLDLMMRIANLEEVQPSALAELNEIME 199 I EHPQ ++LSYL+ +++ ILS P V+ ++ RIA ++ P + E+ ++E Sbjct: 131 FIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLE 190 Query: 200 KQFAGQAGAQAAKIGGLKAAAEIMNYLDNNVEGILMEQIRDQDEDMATQIQDLMFVFENL 259 K+ A + GG+ EI+N D E ++E + ++D ++A +I+ MFVFE++ Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDI 250 Query: 260 VEVDDQGIQKLLRDVPQDVLQKALKGADDSLREKVFKNMSKRAAEMMRDDIEAMPPVRVA 319 V +DD+ IQ++LR++ L KALK D ++EK+FKNMSKRAA M+++D+E + P R Sbjct: 251 VLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRK 310 Query: 320 DVEAAQKEILAIARRMADAGEIMLSGGADE 349 DVE +Q++I+++ R++ + GEI++S G +E Sbjct: 311 DVEESQQKIVSLIRKLEEQGEIVISRGGEE 340
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 276 bits (706), Expect = 1e-87 Identities = 143/557 (25%), Positives = 254/557 (45%), Gaps = 40/557 (7%) Query: 47 GDLDLLRQVVLVLSISICVALIVMLFFWVKEPEMRPL-GAYDTEELIPVLDYLDQQKINY 105 L ++ L+++ S VA++V + W K P+ R L ++ ++ L Q I Y Sbjct: 17 NRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIPY 76 Query: 106 KL--DGNTVSVESSEYNSIKLGMVRSGVNQATEAGDDILLQDMGFGVSQRLEQERLKLSR 163 + + V + + + ++L + + G+ + G + LL FG+SQ EQ + + Sbjct: 77 RFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFE-LLDQEKFGISQFSEQVNYQRAL 135 Query: 164 ERQLAQAIEEMKQVRKARVLLALPKHSVFVRHNQEASASVFLTLSTGANLKQQEVDSIVD 223 E +LA+ IE + V+ ARV LA+PK S+FVR + SASV +TL G L + ++ ++V Sbjct: 136 EGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVVH 195 Query: 224 MVASAVPGMKTSRITVTDQHGRLLSSGSQDPASAARRKEQELERSQEQALREKIDSVLLP 283 +V+SAV G+ +T+ DQ G LL+ + + + E ++ +I+++L P Sbjct: 196 LVSSAVAGLPPGNVTLVDQSGHLLTQSN-TSGRDLNDAQLKFANDVESRIQRRIEAILSP 254 Query: 284 ILGFGNYTAQVDIQMDFSAVEQTRKRFDPNTPSTRSEYALEDYNNGNMVA-----GIPGA 338 I+G GN AQV Q+DF+ EQT + + PN ++++ N V G+PGA Sbjct: 255 IVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPGA 314 Query: 339 LSNQPPADASIP-----------QDVAQ---MKDGSVMGQGSVRKESTRNFELDTTISHE 384 LSNQP P Q+ Q + + G S ++ T N+E+D TI H Sbjct: 315 LSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDRTIRHT 374 Query: 385 RKQTGTVARQTVSVAIKDRRQVNPDTGEVTYTPMSEGEINAIRQVLIGTVGFDQSRGDLL 444 + G + R +V+V + + + P++ ++ I + +GF RGD L Sbjct: 375 KMNVGDIERLSVAVVVNYKTLA-----DGKPLPLTADQMKQIEDLTREAMGFSDKRGDTL 429 Query: 445 NVLSVKFAEPETEQLVDQPIWEHPNFNDWVRWFASALVIIVVVLVLVRPAMKKLLNPAGD 504 NV++ F+ + + P W+ +F D + L+++VV +L R K + P Sbjct: 430 NVVNSPFSAVD-NTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWR----KAVRPQLT 484 Query: 505 DDDEMYGPDGLPIGADGETSLIGSDIESSELFEFGSSIDLPN--LHKDEDVLKAVRALVA 562 E E + L + E + + +R + Sbjct: 485 RRVEEAKAAQEQAQVRQE----TEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSD 540 Query: 563 NEPELAAQVVKNWMNEN 579 N+P + A V++ WM+ + Sbjct: 541 NDPRVVALVIRQWMSND 557
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 59.7 bits (144), Expect = 3e-15 Identities = 28/101 (27%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Query: 3 VDGIQAEMRAMMVEATNTTPTGTGAKVGADFNDLLTKAINNVNSLQKSSGDLQTRFDRGD 62 ++G+ ++++A + A F L A++ ++ Q ++ +F G+ Sbjct: 6 IEGVISQLQATAMSARAQESLPQPT---ISFAGQLHAALDRISDTQTAARTQAEKFTLGE 62 Query: 63 ADVSLSDVMIARNKSSVAFEATVQIRNKLVEAYKDLMNMPV 103 V+L+DVM K+SV+ + +Q+RNKLV AY+++M+M V Sbjct: 63 PGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 489 bits (1261), Expect = e-173 Identities = 172/484 (35%), Positives = 265/484 (54%), Gaps = 20/484 (4%) Query: 1 MAQSKVLIVEDDEGLREALVDTLALAGYEWLEADSAEDALVKLKSNAVDIVVSDVQMAGM 60 M + +L+ +DD +R L L+ AGY+ +A + + D+VV+DV M Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 GGLALLRNIKQNWPNLPVLLMTAYANIEDAVSAMKDGAIDYMAKPFAPEVLLNMVSR--- 117 LL IK+ P+LPVL+M+A A+ A + GA DY+ KPF L+ ++ R Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 118 ------YAPIKSDDNGDAVVADEKSLR-LLALADKVARTDANVMILGPSGSGKEVMSRYI 170 +G +V +++ + + ++ +TD +MI G SG+GKE+++R + Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 171 HKASNRKDGPFVAINCAAIPDNMLEATLFGYEKGAFTGAVQACPGKFEQAQGGTILLDEI 230 H R++GPFVAIN AAIP +++E+ LFG+EKGAFTGA G+FEQA+GGT+ LDEI Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 231 SEMDLNLQAKLLRVLQEREVERLGSRKSIKLDVRVLATSNRDLKQYVSEGNFREDLYYRL 290 +M ++ Q +LLRVLQ+ E +G R I+ DVR++A +N+DLKQ +++G FREDLYYRL Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 291 NVFPIAWPALNERKGDIAPLAKHLAERHCSKMGMPVPQFSPVAVEKLLQYPWPGNVRELD 350 NV P+ P L +R DI L +H ++ K G+ V +F A+E + +PWPGNVREL+ Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVRELE 359 Query: 351 NVVQRALILSENGDIGAEHILLEGVDWQDANSLQYV-----VQSAETLVPDVKPVAQAES 405 N+V+R L I E I E + ++ S V + A Sbjct: 360 NLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 406 VNRVNTGGEGLGGELRDQEYAIILETLVECNGRRKEMAEKLGISPRTLRYKLAKMRDAGI 465 + + G L + EY +IL L G + + A+ LG++ TLR K+ ++ G+ Sbjct: 420 GDALPPSGL-YDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL---GV 475 Query: 466 DIPS 469 + Sbjct: 476 SVYR 479
>PF06580#Sensor histidine kinase Length = 349 Score = 31.0 bits (70), Expect = 0.007 Identities = 19/126 (15%), Positives = 47/126 (37%), Gaps = 24/126 (19%) Query: 216 IDYFLEVEEEQTELLGNANAIASALSNLVMNAIQ--MSGKES--QIDIFFRPVNGELRIS 271 + + ++ + + + LV N I+ ++ +I + NG + + Sbjct: 240 LQFENQINPA----IMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLE 295 Query: 272 VQDSGPGVPQELQAKIMEPFFTTRSQGTGLGLAVVQMVCRA---HDGRLELISEQGDGAC 328 V+++G + + + TG GL V+ + + +++L +QG Sbjct: 296 VENTGSLALKNTK------------ESTGTGLQNVRERLQMLYGTEAQIKLSEKQG-KVN 342 Query: 329 FTMCIP 334 + IP Sbjct: 343 AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 523 bits (1349), Expect = 0.0 Identities = 178/497 (35%), Positives = 268/497 (53%), Gaps = 31/497 (6%) Query: 1 MQGLAKLLVIDDDASSRLNLSNILEFVGESCEAVGSEQLGDVDWSSVWSGCIVGNIS-AG 59 M G A +LV DDDA+ R L+ L G + ++ +V ++ Sbjct: 1 MTG-ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 60 RAATAVMARLNDAY-HIPLLVLGSFPLPVDDLPNFVGELEQ--------PLNYPQLSEAL 110 A ++ R+ A +P+LV+ + + E+ P + +L + Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQN----TFMTAIKASEKGAYDYLPKPFDLTELIGII 115 Query: 111 RHCKDFLGRKGVNVVASARKNTLFRSLVGQSRGIQEVRHLIEQVSGTEANVLILGESGTG 170 R+ + ++ LVG+S +QE+ ++ ++ T+ ++I GESGTG Sbjct: 116 GRALAEPKRRPSKLEDDSQD---GMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTG 172 Query: 171 KEVVARNIHYHSSYRNGAFVPINCGAIPPELLESELFGHEKGAFTGALTARKGRFELADG 230 KE+VAR +H + RNG FV IN AIP +L+ESELFGHEKGAFTGA T GRFE A+G Sbjct: 173 KELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEG 232 Query: 231 GTIFLDEIGDMPMSMQVKLLRVLQERCFERVGGNSTIKVNVRVVAATHRNLESMIEEGTF 290 GT+FLDEIGDMPM Q +LLRVLQ+ + VGG + I+ +VR+VAAT+++L+ I +G F Sbjct: 233 GTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLF 292 Query: 291 REDLFYRLNVFPIEMPALKERKQDIPLLLQELMTRLEAEGGQPICFTPRAINSLMEHHWP 350 REDL+YRLNV P+ +P L++R +DIP L++ + + E EG F A+ + H WP Sbjct: 293 REDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWP 352 Query: 351 GNVRELANLVERMIILYPNSLVDVNHLPTKYRYSDIPEFQPEGNPFTSIEEQERDVFQDI 410 GNVREL NLV R+ LYP ++ + + R S+IP+ E S ++ Sbjct: 353 GNVRELENLVRRLTALYPQDVITREIIENELR-SEIPDSPIEKAAARSGSLSISQAVEEN 411 Query: 411 FSEDFSFDEQSDLDHNMNAPQALPPEGVNLKELLADLEVNMISQALEAQGGVVARAADML 470 + F+ + ALPP G+ +LA++E +I AL A G +AAD+L Sbjct: 412 MRQYFA-----------SFGDALPPSGL-YDRVLAEMEYPLILAALTATRGNQIKAADLL 459 Query: 471 GMRRTTLVEKMRKYNLQ 487 G+ R TL +K+R+ + Sbjct: 460 GLNRNTLRKKIRELGVS 476
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.5 bits (76), Expect = 0.003 Identities = 46/260 (17%), Positives = 83/260 (31%), Gaps = 17/260 (6%) Query: 244 NPLPPEAQKAADNA--QDDAQDDASQEPISAAGAEAAKAGQEAIDKANQRSSLRPEERIP 301 N P +A + ++ + E A A + N + + E+ Sbjct: 996 NITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN- 1054 Query: 302 GWTETASGTLLDSYEEPELELDEKAIEKAPDVPGWNNAASGTLTDSYVTTKEAKQLLEQE 361 + A+ T + E + ++A N A T E K+ E Sbjct: 1055 --EQDATETTAQNRE-----VAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE 1107 Query: 362 KAEIEQKIADEKQELDAKVERGELSEEQAKQIHRAKLDPQERERLEKIDEAEAKIAKAQS 421 K E + K+ EK + KV S+ KQ + PQ E K ++Q+ Sbjct: 1108 KEE-KAKVETEKTQEVPKVT----SQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQT 1162 Query: 422 SFEEYLGMTEVQAGQDSEVLLDGVAKLSSHNNVIEDAIEGVDLTLKGKSEPNKPPAEIGV 481 + + + E + +++ N+V+E+ + N + Sbjct: 1163 NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPEN--TTPATTQPTVNSESSNKPK 1220 Query: 482 EYDRQSVRSDIENFVSAYNS 501 R+SVRS N A S Sbjct: 1221 NRHRRSVRSVPHNVEPATTS 1240
>FLAGELLIN#Flagellin signature. Length = 507 Score = 182 bits (463), Expect = 5e-55 Identities = 85/295 (28%), Positives = 134/295 (45%), Gaps = 8/295 (2%) Query: 2 AINVNTNVSAMTAQRYLNHAAEGQQKSMERLSSGYKINSAKDDAAGLQISNRLNAQSRGL 61 A +NTN ++ Q LN + ++ERLSSG +INSAKDDAAG I+NR + +GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DMAVKNANDGISIAQVAEGAMNESTNILQRMRDLSLQSANGSNSKAERVAIQEEVTALND 121 A +NANDGISIAQ EGA+NE N LQR+R+LS+Q+ NG+NS ++ +IQ+E+ + Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 ELNRIAETTSFGGNKLLNGTYGTQSFQIGADSGEAVMLSMGSLRSDTSAMGGKSYSAEEG 181 E++R++ T F G K+L+ Q+GA+ GE + + + + + + G + + Sbjct: 121 EIDRVSNQTQFNGVKVLSQD-NQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNG--- 176 Query: 182 KDASWTVGDKTELKMSYTNKQGEEKELTIKAKQGDDIEQLATYINGQSEDVKASVGEDGK 241 +LK S+ N G + K D+ A + + V V + Sbjct: 177 ----PKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAA 232 Query: 242 LQVFASTQKVNGEVEFSGNLAGEIGFGDAKDVTVKDIDVTTVAGSQEAVAVIDGA 296 + N I + + V Sbjct: 233 NGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTI 287 Score = 125 bits (314), Expect = 6e-34 Identities = 76/338 (22%), Positives = 127/338 (37%), Gaps = 24/338 (7%) Query: 57 QSRGLDMAVKNANDGISIAQVAEGAMNESTNILQRMRDLSLQSANGSNSKAERVAIQEEV 116 + + V + + + + ++ + + + ++V + Sbjct: 174 VNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNA-A 232 Query: 117 TALNDELNRIAETTSFGGNKLLNGTYGTQSFQIGADSGEAVMLSMGSLRSDTSAMGGKSY 176 + T + ++ I + T + K+ Sbjct: 233 NGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTG 292 Query: 177 SAEEGKDASWTVGDKTELKMSYTNKQGEEKELTIKAKQGDDIEQL-ATYINGQSEDVKAS 235 + GK ++ G K++ T + A + + + +NGQ + Sbjct: 293 NDGNGKVSTTING----EKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKT 348 Query: 236 VGEDGKLQVFASTQKVNGEVEFSGNLAGEIGFGDAKDVTV------------------KD 277 E KL + V GE + + N A VT+ + Sbjct: 349 KNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINE 408 Query: 278 IDVTTVAGSQEAVAVIDGALKSVDSQRASLGAFQNRFNHAISNLDNINENVNASNSRIKD 337 + +A ID AL VD+ R+SLGA QNRF+ AI+NL N N+N++ SRI+D Sbjct: 409 DAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIED 468 Query: 338 TDYAKETTAMTKSQILQQASTSILAQAKQSPSAALSLL 375 DYA E + M+K+QILQQA TS+LAQA Q P LSLL Sbjct: 469 ADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>FLAGELLIN#Flagellin signature. Length = 507 Score = 199 bits (506), Expect = 3e-61 Identities = 91/297 (30%), Positives = 142/297 (47%), Gaps = 2/297 (0%) Query: 2 AITVNTNVAALVAQRHLTSATDMLNQSMERLSSGKRINSAKDDAAGLQISNRLQSQMSGL 61 A +NTN +L+ Q +L + L+ ++ERLSSG RINSAKDDAAG I+NR S + GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DVAVRNANDGISIMQTAEGAMNEVTNIMQRMRDLSLQSANGSNSQVERTALQEEVTALND 121 A RNANDGISI QT EGA+NE+ N +QR+R+LS+Q+ NG+NS + ++Q+E+ + Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 ELNRIAETTSFGGRKLLNGAFGKSSFQIGAASGEAVQIELKSMRTDGLEMGGFSYVAQGR 181 E++R++ T F G K+L+ Q+GA GE + I+L+ + L + GF+ Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQM-KIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 ADSDWQVKENANDLTMSFINRSGETEKIQINAKSGDDIEELATYINGQTDKVTASVNEKG 241 A N ++ +N+ + T + Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 242 QLQIFMAGEDTAGTISFSGDL-ASELGMSLKGYDAVNNLNITTVGGAQQAVAVLDTA 297 + A + T S +G A + ++KG + + V D Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGN 296 Score = 126 bits (318), Expect = 2e-34 Identities = 59/213 (27%), Positives = 90/213 (42%), Gaps = 19/213 (8%) Query: 183 DSDWQVKENANDLTMSFINRSGETEKIQINAKSGDDIEEL-ATYINGQTDKVTASVNEKG 241 D + +V N ++ ++A + + + + +NGQ + NE Sbjct: 294 DGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESA 353 Query: 242 QLQIFMAGEDTAGTISFSGDLASELGMSLKGYDAV------------------NNLNITT 283 +L A G + + A + + N Sbjct: 354 KLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAA 413 Query: 284 VGGAQQAVAVLDTAMKFVDSQRAELGAYQNRFNHAINNLDNIHENLAASNSRIQDTDYAK 343 +A +D+A+ VD+ R+ LGA QNRF+ AI NL N NL ++ SRI+D DYA Sbjct: 414 KKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYAT 473 Query: 344 ETTQMVKQQILQQVSTTILAQAKQAPNLALTLL 376 E + M K QILQQ T++LAQA Q P L+LL Sbjct: 474 EVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 104 bits (260), Expect = 2e-27 Identities = 104/399 (26%), Positives = 157/399 (39%), Gaps = 78/399 (19%) Query: 1 MKKTLIALSVSAAAMATGVNAAELYNQDGTSLEMGGRAEARLSMKDGDAQ--DNSRIRLN 58 MK+ ++AL + A A +AAE+YN+DG L++ G+ + D ++ D + +R+ Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 59 FLGTQAINDNLYGVGFWEGEFTTNEQGGVDGDVNKDSSNLDTRYAYAGLG-GAWGEFTYG 117 F G IND L G G WE N G + +N TR A+AGL G +G F YG Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEG-------EGANSWTRLAFAGLKFGDYGSFDYG 113 Query: 118 KNEGALGVITDFTDIMAYHGNSA--------------------ADKLAVADRSDNMMSYK 157 +N G L + +TD++ G + D + D + + Y+ Sbjct: 114 RNYGVLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQ 173 Query: 158 GQFENLSVKASYRFADRKLNDAGTEYTDNGQDGYSLSAIYAVADTGLELGAGYADQDEAN 217 G+ E+ S + + N Y DNG DG+ +S Y + G GA Y D N Sbjct: 174 GKNESQSADDVNIGTNNRNNGDDIRY-DNG-DGFGISTTYDI-GMGFSAGAAYTTSDRTN 230 Query: 218 E----------------YMLAASYTMGDLYFAGIFTDGEKAKTEGDYTGYELAGAYTLGQ 261 E + Y ++Y A ++++ G G Q Sbjct: 231 EQVNAGGTIAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQ 290 Query: 262 TVFTT-----------------------TYNNAETNNETSANNFAVDASYYFKPNFRGYV 298 T TYNN +++ V A+YYF NF YV Sbjct: 291 NFEVTAQYQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYV 350 Query: 299 SYNFNLIDSGDKLGKVGGNTTASKADAEDELALGLRYDF 337 Y NL+D D K G +T +D +ALG+ Y F Sbjct: 351 DYKINLLDDDDPFYKDAGIST------DDIVALGMVYQF 383
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 32.1 bits (73), Expect = 0.004 Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 12/98 (12%) Query: 7 LLISSLIFPLLSYAYPHQEVLPE--------GARISLVAEKLTESSTLDGIRPTDQLFPP 58 L I SL+ L + + L + R+ ++ L TL R D+ FP Sbjct: 6 LCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRA-DERFPM 64 Query: 59 ASTLKIVTALA--AKLELGDSFAFRTKLETSSSDAVIY 94 ST K+V A A+++ GD K+ D V Y Sbjct: 65 MSTFKVVLCGAVLARVDAGDEQ-LERKIHYRQQDLVDY 101
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 510 bits (1315), Expect = e-166 Identities = 220/1045 (21%), Positives = 435/1045 (41%), Gaps = 54/1045 (5%) Query: 8 ALSRSRTMLTLLVMILIAGVITYVTIPKESSPDITIPIIYVSVGHQGISPTDAERLLVRP 67 + R L +++++AG + + +P P I P + VS + G + + + Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 68 IEQELRSIEGVKEMTSVA-SEGHASVTLEFSVGVDLDKAMADVRDAVDLAKPKLPADSDE 126 IEQ + I+ + M+S + S G ++TL F G D D A V++ + LA P LP + + Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 127 PTVNEVTFASEEPVLTVVLYGTVPERTIVQI----ARTLRDRLESFRQILEVDIAGDRED 182 ++ V +S ++ P T I A ++D L + +V + G + Sbjct: 125 QGIS-VEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-AQY 182 Query: 183 IVEIVVDPLLMESYGLDQADIYNLIALNNRVVAAGFVDTG------YGRFSVKVPSVFDS 236 + I +D L+ Y L D+ N + + N +AAG + S+ + F + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 237 LKDVLELPIKVNGK-EVITFGDVATVRRAFRDPESFARLDGEPAIVLDVKKRAGENIIET 295 ++ ++ ++VN V+ DVA V + AR++G+PA L +K G N ++T Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 296 VALVKEVIAQGQLRAEWPSNLQVKYTWDQSDDVKLMLSDLQNNILSAIILVVIVIIAILG 355 +K +A+ L+ +P ++V Y +D + V+L + ++ + AI+LV +V+ L Sbjct: 303 AKAIKAKLAE--LQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 356 -VRTALLVGISIPGSFLTGLLVLSVFGLTVNIVVLFALIMAVGMLVDGAIVVTEFADRRM 414 +R L+ I++P L +L+ FG ++N + +F +++A+G+LVD AIVV E +R M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 415 QE-GTPRKEAYRDAAKRMAWPITASTATTLAAFAPLLFWPDITGEFMKYLPLTLIATLAA 473 E P KEA + ++ + A F P+ F+ TG + +T+++ +A Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 474 SLVMALLFVPVIGGIIGKPQVINPKAQQEMVELHNGNFEKATGITKLYYKTLFVAIQHPW 533 S+++AL+ P + + KP + + Y ++ + Sbjct: 481 SVLVALILTPALCATLLKPVS--AEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 534 KVLLSAVLLAGGVGFTYSKAGLGAEFFPEVDPPFFTVKVRSYGDLSINEKDIVMREIEKV 593 + LL L+ G+ + + L + F PE D F ++ + V+ ++ Sbjct: 539 RYLLIYALIVAGMVVLFLR--LPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDY 596 Query: 594 MLGH--DEFESVYTRTG--SSDNGDEIGQIQITPVDWQYR-RKVKTIIEELKATTDQFYG 648 L + ESV+T G S G ++ W+ R + + + Sbjct: 597 YLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGK 656 Query: 649 VELEYKFPDAGPPVE-------HDLVIEVSSRSRSIGELDDAAKLVRLWADSNPALTNLS 701 + + P P + D + + +L+ + A +L ++ Sbjct: 657 IRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVR 716 Query: 702 DTTNKVGIDWQIDIRRDDASRFAADATLVGNTVQFVTNGLKIGDYLPDDADEEVDILVRY 761 + +++++ ++ A + + T+ G + D++ + V+ Sbjct: 717 PNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDR--GRVKKLYVQA 774 Query: 762 PQEKR-DIGRFDQLRVKTAAG-LVPITNFAQIKPDHKQDTIRRVDGHRVINIKADMVEGY 819 + R D+L V++A G +VP + F + + R +G + I+ + G Sbjct: 775 DAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGT 834 Query: 820 NLALELPKIAAEMEQLGLPEGVEYKIRGQNEEQENSSAFLQNAFVVALGVMALILITQFN 879 + + + + LP G+ Y G + ++ S ++ V+ L L + Sbjct: 835 SSGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYE 892 Query: 880 SFYQAFLILSAVLFSTVGVFAGLLIFQKPFGIIMSGIGVIALAGIVVNNNIVLIDTYNQ- 938 S+ ++ V VGV +F + + +G++ G+ N I++++ Sbjct: 893 SWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVY-FMVGLLTTIGLSAKNAILIVEFAKDL 951 Query: 939 MRKRGLDKAEAILRTGVQRLRPVLLTTITTILGLLPMVLEMNIDLVNQKVEFGAPSTQWW 998 M K G EA L RLRP+L+T++ ILG+LP+ + GA S Sbjct: 952 MEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAI-----------SNGAGSGAQN 1000 Query: 999 SQLATAVAGGLAFATVLTLVLTPCL 1023 + + V GG+ AT+L + P Sbjct: 1001 A-VGIGVMGGMVSATLLAIFFVPVF 1024
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.0 bits (96), Expect = 5e-06 Identities = 35/226 (15%), Positives = 79/226 (34%), Gaps = 28/226 (12%) Query: 53 LAKVMFDTFTAKPTSKTIELYGRTAPNRQARLGAEVAGKIVSLSINKGQ------LVKQG 106 L K F T+ + K + L + A + + A + + K + L+ + Sbjct: 190 LIKEQFSTWQNQKYQKELNLDKKRA--ERLTVLARINRYENLSRVEKSRLDDFSSLLHKQ 247 Query: 107 QVIANIDKRDLDSQLKRAQAMLRVKEKEFNAAKS------LKSRGLQGEV------AFAT 154 IA + +++ A LRV + + +S + + + Sbjct: 248 -AIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQ 306 Query: 155 AEAALVDARANLNNVQTALKNTEVKAPFDGIVDHHFV-EVGDFVGVGDPIATVI-DLETL 212 + L + + + ++AP V V G V + + ++ + +TL Sbjct: 307 TTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTL 366 Query: 213 VIEADVSERHIQYLKEGLQADVR--TINGQHHLGTLRYIGRVSSVS 256 + A V + I ++ G A ++ + G L G+V +++ Sbjct: 367 EVTALVQNKDIGFINVGQNAIIKVEAFPYTRY-GYLV--GKVKNIN 409 Score = 30.6 bits (69), Expect = 0.010 Identities = 24/104 (23%), Positives = 36/104 (34%), Gaps = 19/104 (18%) Query: 177 EVKAPFDGIVDHHFVEVGDFVGVGDPIATVIDLETLVIEADVSERHIQYLKEGLQADVRT 236 E+K + IV V+ G+ V GD + L L EAD + L+ L+ Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLK---LTALGAEADTLKTQSSLLQARLEQ---- 150 Query: 237 INGQHHLGTLRYIGRVSSVSTNTFPIEIEIDNRNSLIPAGISAE 280 RY S+ N P E+ + +S E Sbjct: 151 ---------TRYQILSRSIELNKLP---ELKLPDEPYFQNVSEE 182
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 29.0 bits (65), Expect = 0.021 Identities = 27/107 (25%), Positives = 40/107 (37%), Gaps = 7/107 (6%) Query: 335 LTEPIPMAVLAGIAVYVGFNILDWSFIQRAHKVSFSGMAIMYGVMLLTVFVDLIVAVGLG 394 L I M L + + F + + M YGV + VF LIVA + Sbjct: 36 LVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMH--YGVFIQNVFDFLIVAFAIF 93 Query: 395 VFVSNIMIIERLSREQARQVKAISDADEDDVPLTDSERGLLDRANGR 441 + I +I +L+R++ A A + L R LL N R Sbjct: 94 MA---IKLINKLNRKKEEPAAA--PAPTKEEVLLTEIRDLLKEQNNR 135
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 29.0 bits (65), Expect = 0.022 Identities = 27/116 (23%), Positives = 43/116 (37%), Gaps = 11/116 (9%) Query: 82 FSDPLLNLLSSHSETQLDLLESRHAMEGISAYFAALRGTEEDFARIQGCLERISKEQANN 141 F L + +T L L+ H E ++A+F I SKE Sbjct: 54 FKTSSLPITEVAEKTGLTFLQLNHYCEELNAFFPDSLSMTIQKRMISCQFTHPSKETYLY 113 Query: 142 DIEAESAEVMQFL-IAITEAAHNVVL------LHIVRSLAPLLEQNI---LQNFKL 187 + A S V+Q L I +H+ L + S A + + + L+NF+L Sbjct: 114 QLYASS-NVLQLLAFLIKNGSHSRPLTDFARSHFLSNSSAYRMREALIPLLRNFEL 168
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 49.9 bits (119), Expect = 1e-10 Identities = 19/62 (30%), Positives = 36/62 (58%) Query: 5 KQKKQQGFTLIELMIVVAIIGVLAAAAIPAYQNYVTRSEVTSGLATVKALITPAELHYQE 64 KQ+GFTL+E+M+V+ IIGVLA+ +P +++ ++ + AL +++ + Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLD 62 Query: 65 NG 66 N Sbjct: 63 NH 64
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 435 bits (1121), Expect = e-154 Identities = 105/407 (25%), Positives = 213/407 (52%), Gaps = 9/407 (2%) Query: 8 LKNFRWKGVNSSGKKTSGQTLAMSEIEVRERLDAQHI--------KIKKLKKSSISFLTK 59 + + ++ +++ GKK G A S + R+ L + + + + K S + Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 60 LSHRVKGKDITVFTRQISTMLVTGVPLVQALKLVSDNHKKAEMKSILMSVTRAVEAGTPM 119 R+ D+ + TRQ++T++ +PL +AL V+ +K + ++ +V V G + Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 120 SKAMRTASNHFDPLYTDLIATGEQSGNLAEVFERLATYREKNEQLRAKVIKALIYPAMVI 179 + AM+ F+ LY ++A GE SG+L V RLA Y E+ +Q+R+++ +A+IYP ++ Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 180 LVALGVSFIMLTKVIPEFEKMFVGFGAELPWFTRQVLDLSAWTQNWSPFIALGSISVFIS 239 +VA+ V I+L+ V+P+ + F+ LP TR ++ +S + + P++ L ++ F++ Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 ARVLSKRSDSFRLMLNRSVLKFPVLGAVLSKAAIAKFSRTLATSFTAGIPILTSLKTTSK 299 RV+ R + R+ +R +L P++G + A+++RTL+ + +P+L +++ + Sbjct: 241 FRVM-LRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGD 299 Query: 300 TSGNMHYQLAIEEVYRDTAAGMPMYVAMRNCNVFPELVLQMVMIGEESGRLDDMLNKVAT 359 N + + + G+ ++ A+ +FP ++ M+ GE SG LD ML + A Sbjct: 300 VMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAAD 359 Query: 360 IYEFEVDNTVDNLSKILEPLIIVFLGIVVGGLVTAMYLPIFNLMSVL 406 + E + + + EPL++V + VV +V A+ PI L +++ Sbjct: 360 NQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 359 bits (924), Expect = e-128 Identities = 155/287 (54%), Positives = 195/287 (67%), Gaps = 1/287 (0%) Query: 1 MEVFQYYPWLFVVFASIFGLIVGSFLNVVIYRLPKIMELEWRRECAESFPEYKIKPPQEV 60 +E+ PWL+ +F L++GSFLNVVI+RLP ++E EW+ E F + Sbjct: 5 LELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEPP 64 Query: 61 LTLSVPRSSCQNCATPIRIRDNIPVISWLLLKGKCHHCHTAISPRYPLIELLTAACAGFV 120 L VPRS C +C PI +NIP++SWL L+G+C C IS RYPL+ELLTA + V Sbjct: 65 YNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAV 124 Query: 121 AYHFGFSYFTVALIFFTFFLIAATFIDLDTMLLPDQLTLPLTWAGIALALTEISPVSLQD 180 A + T+A + T+ L+A TFIDLD MLLPDQLTLPL W G+ L VSL D Sbjct: 125 AMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLG-GFVSLGD 183 Query: 181 AVIGAIAGYLCLWSVYWGFKLLTGKEGMGYGDFKLLAALGAWLGWQSLPMIILLSSVVGV 240 AVIGA+AGYL LWS+YW FKLLTGKEGMGYGDFKLLAALGAWLGWQ+LP+++LLSS+VG Sbjct: 184 AVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGA 243 Query: 241 IFGLVQLRLQKQGIERAFPFGPYLAIAGWVSLIWGDQILSWYFTSIL 287 G+ + L+ + PFGPYLAIAGW++L+WGD I WY T+ L Sbjct: 244 FMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYLTNFL 290
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.9 bits (80), Expect = 4e-05 Identities = 11/27 (40%), Positives = 19/27 (70%) Query: 9 GFTLMELILVIVLLSILSLYAASRFMG 35 GFTL+E+++VIV++ +L+ MG Sbjct: 9 GFTLLEIMVVIVIIGVLASLVVPNLMG 35
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 35.2 bits (81), Expect = 6e-06 Identities = 11/35 (31%), Positives = 21/35 (60%) Query: 1 MVHMRKSSGLSAIEFVVVLIILGVVGYVVLPRFIS 35 M K G + +E +VV++I+GV+ +V+P + Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMG 35
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 51.0 bits (122), Expect = 6e-11 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 4/54 (7%) Query: 1 MKRQGGFTLIELVVVIVILGILAVTAAPRFLNLQSDARE----SALQGLKGAID 50 +Q GFTL+E++VVIVI+G+LA P + + A + S + L+ A+D Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALD 57
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 278 bits (712), Expect = 2e-92 Identities = 114/399 (28%), Positives = 197/399 (49%), Gaps = 2/399 (0%) Query: 1 MPTFRYQGRTLDGSSTSGKVDAVNSEAAAEALMNKGIIPLNLRLEKEGVKNHVSLSKLLV 60 M + YQ G G +A ++ A + L +G++PL++ + + S L Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 61 PAIPLEV--IILFSRQLFSLTKAGVPLLRSMRGLLQNCENKQLKEALEDVVSELSNGRGL 118 I L + L +RQL +L A +PL ++ + + E L + + V S++ G L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 119 SSAMQPHNKVFSPLFVSMINVGENTGRLDEALLQLANYYEQELETRKRIKAAMRYPTFVI 178 + AM+ F L+ +M+ GE +G LD L +LA+Y EQ + R RI+ AM YP + Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 179 VFITIAMFILNILVIPEFASMFTRFGVELPLPTRILIATSNFFVHYWGLLIAAMVGAFFV 238 V + IL +V+P+ F LPL TR+L+ S+ + ++ A++ F Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 239 FKAWVATAGGREKFDKFRLRLPIVGDIVNRAQLSRFARTFSLMLKSGVPLNQSLALAGEA 298 F+ + R F + L LP++G I +R+ART S++ S VPL Q++ ++G+ Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 299 LGNRFLENRILEMKAAIEAGSTISVTAINSNIFTPLVIQMIAVGEETGRIDELLLEVSDF 358 + N + +R+ A+ G ++ + +F P++ MIA GE +G +D +L +D Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 359 YDREVDYDLKTLTARIEPLLLVIVAGMVMVLALGIFLPM 397 DRE + EPLL+V +A +V+ + L I P+ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPI 399 Score = 67.9 bits (166), Expect = 1e-14 Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 1/126 (0%) Query: 71 FSRQLFSLTKAGVPLLRSMRGLLQNCENKQLKEALEDVVSELSNGRGLSSAMQPHNKVFS 130 ++R L L + VPLL++MR N + L + G L A++ +F Sbjct: 276 YARTLSILNASAVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVSLHKALE-QTALFP 334 Query: 131 PLFVSMINVGENTGRLDEALLQLANYYEQELETRKRIKAAMRYPTFVIVFITIAMFILNI 190 P+ MI GE +G LD L + A+ ++E ++ + + P V+ + +FI+ Sbjct: 335 PMMRHMIASGERSGELDSMLERAADNQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLA 394 Query: 191 LVIPEF 196 ++ P Sbjct: 395 ILQPIL 400
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 182 bits (462), Expect = 5e-52 Identities = 76/314 (24%), Positives = 138/314 (43%), Gaps = 26/314 (8%) Query: 222 QQAVANLIGSGKGQSVVVTPQAGVITVRAFPDDIREVREFLGVSQERMQRQVILEAKILE 281 +QA + K + Q + V A PD + ++ + + + QV++EA I E Sbjct: 297 KQAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIA-QLDIRRPQVLVEAIIAE 355 Query: 282 VTLSDGYQQGINWSNLSASIGN--SGSIIVNRPASALPPLDAIGTLLGGQTN-------- 331 V +DG GI W+N +A + + + ++ + + GT+ + Sbjct: 356 VQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGI 415 Query: 332 -VTISDGNFEAVLNFMSTQGDLNVLSSPRITAANNQKSVIKVGTDQYFVTELSSNAGNGE 390 GN+ +L +S+ ++L++P I +N ++ VG + +T S +G+ Sbjct: 416 AAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLT--GSQTTSGD 473 Query: 391 NSNAVPEVELTPFFSGISLDVTPQIDNKGNVFLHVHPAVIEVTEEVKQLNLGGDFQNIQL 450 N E + GI L V PQI+ +V L + V V + + Sbjct: 474 NIFNTVERKTV----GIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLG------ 523 Query: 451 PLAKSSIRESDSVIRAKDGDVVVIGGLMKQQNVEQVSKVPFLGDVPALGHLFRNTSNVTQ 510 A + R ++ + G+ VV+GGL+ + + KVP LGD+P +G LFR+TS Sbjct: 524 --ATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVS 581 Query: 511 KTELVILLKPTVVG 524 K L++ ++PTV+ Sbjct: 582 KRNLMLFIRPTVIR 595 Score = 34.9 bits (80), Expect = 8e-04 Identities = 21/90 (23%), Positives = 41/90 (45%), Gaps = 6/90 (6%) Query: 68 SKRFRIQANAVEARSFFASLVKGTEYSVAIHPAVQGNITVNLSDVT----LDEVLSVVQN 123 ++ F + + F ++ K +V I P+V+G ITV D+ + V + Sbjct: 27 AEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLD 86 Query: 124 MYGYDVMKSGK-VIQVYPA-GMRTVTIPVD 151 +YG+ V+ V++V + +T +PV Sbjct: 87 VYGFAVINMNNGVLKVVRSKDAKTAAVPVA 116
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.001 Identities = 7/27 (25%), Positives = 16/27 (59%) Query: 123 IEADKSGVVTAILVEDGQPVEFDQPLV 149 I+ ++ +V I+V++G+ V L+ Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLL 125
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 148 bits (374), Expect = 3e-50 Identities = 81/98 (82%), Positives = 89/98 (90%) Query: 1 MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVTELYELVLAEVEQ 60 MFEQ + S+ LTV+TV SQDQ+TQKPLRDSVK +LKNY AQLNGQ+V +LYELVLAEVEQ Sbjct: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 Query: 61 PLLDTIMQYTRGNQTRAATMMGINRGTLRKKLKKYGMN 98 PLLD +MQYTRGNQTRAA MMGINRGTLRKKLKKYGMN Sbjct: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 76.8 bits (189), Expect = 1e-17 Identities = 79/348 (22%), Positives = 135/348 (38%), Gaps = 23/348 (6%) Query: 41 LFITAYSLAIAFCAPYLGRWSDRVGRLRLMLPACFVFGISSILTGLVGQFEWALVTRVVT 100 + + Y+L CAP LG SDR GR ++L + + + + R+V Sbjct: 47 ILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVA 106 Query: 101 GIASAGMLPIAFALAGDAKGGRSMRQIVMVQAGLTLGMITSPAIGALITQLLSWRAAFII 160 GI A +A G R + A GM+ P +G L+ S A F Sbjct: 107 GITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFA 165 Query: 161 LGMAALAVGALVWGC--MREPHDQNERLMTL--PPVIEAFRLPGALGAIAAMCFGLGGGI 216 AAL + GC + E H R + + +FR + +AA+ + + Sbjct: 166 --AAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMA-VFFIM 222 Query: 217 GVFNLIGLNM-----RDVAGLSISWIGMMYAALGIVSVLGN-LLTTRASHRLGSGRAVMR 270 + + + D + IG+ AA GI+ L ++T + RLG RA Sbjct: 223 QLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRA--- 279 Query: 271 IALMVCMPCSIWVFACGASQFVAYLPILAIWSLAGGIGSPALQAYIA-SLSDEYRGVLMS 329 + L + + ++ A++ PI+ + +GGIG PALQA ++ + +E +G L Sbjct: 280 LMLGMIADGTGYILLAFATRGWMAFPIM-VLLASGGIGMPALQAMLSRQVDEERQGQLQG 338 Query: 330 SAMSMMHFGVAIWSALAGFAYDVGSE----WVAVLAVLLFGFAIAALK 373 S ++ + L Y W + L+ + AL+ Sbjct: 339 SLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALR 386
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.009 Identities = 12/21 (57%), Positives = 17/21 (80%) Query: 349 LVIEGFNGVGKSTLLKTLMGE 369 +V+EG G+GKSTL+ TL+G Sbjct: 599 VVLEGTGGIGKSTLINTLVGL 619