>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 36.5 bits (84), Expect = 4e-04 Identities = 58/233 (24%), Positives = 80/233 (34%), Gaps = 26/233 (11%) Query: 91 LTSPAKTSLKIPPNAKIKKSTLLVLKGENAEEVANILGISKEEYQKLENIAQTNATNDPM 150 + +P + K PN K +T K + E N S + N AQ Sbjct: 323 IIAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNN---SNTQVINPPNSAQKTEIQPTQ 379 Query: 151 YANTPFNNNPNS-PNDNAINGKDSANGSNGYGING--NDGINGSSGSNGNNSNNNAVGSG 207 + PF N+ N N IN G + + G G N +N A G Sbjct: 380 VIDGPFAGGKNTVVNINRINTNADGTIRVGGFKASLTTNAAHLHIGKGGINLSNQASGRS 439 Query: 208 IDTDGVLG---VDGVNGSNSSSGGS-VGGYENNFT--------NHGSTNNNTGGYDHFNN 255 + + + G VDG N+ GG + G NF N +T NN F N Sbjct: 440 LLVENLTGNITVDGPLRVNNQVGGYALAGSSANFEFKAGTDTKNGTATFNNDISLGRFVN 499 Query: 256 -------NSSSGGGLGNGGLFPIPFGNGDTNNSNNPTNTTSPTNGSSSNNATN 301 + G GNGG + F +G TN N T+ TN + N N Sbjct: 500 LKVDAHTANFKGIDTGNGGFNTLDF-SGVTNKVNINKLITASTNVAVKNFNIN 551
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 62.0 bits (150), Expect = 2e-13 Identities = 62/263 (23%), Positives = 109/263 (41%), Gaps = 29/263 (11%) Query: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGA-ILAFTYLNESLEKRVRPIAQELNSPYVYE 62 ++GK I G A + I +A++ +QGA I A Y E LEK V + E + Sbjct: 6 IEGKIAFITGAA--QGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 63 LDVSKEEHFKPLYDSVKKDLGSLDFIVHSVAF--------APKEALEGSLLETSKSAFNT 114 DV + +++++G +D +V+ E E + S FN Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 115 AMEISVYSLIELTNTLKPLLNNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAV 174 + +S Y + + ++ + +N A V S MA Y +KAA + L + Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTS-------MAAY---ASSKAAAVMFTKCLGL 173 Query: 175 DLGKHNIRVNALSAGPIRT-----LASSGIADFRMILKWNE---INAPLRKNVSLEEVGN 226 +L ++NIR N +S G T L + ++I E PL+K ++ + Sbjct: 174 ELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIAD 233 Query: 227 AGMYLLSSLSSGVSGEVHFVDAG 249 A ++L+S + ++ VD G Sbjct: 234 AVLFLVSGQAGHITMHNLCVDGG 256
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 28.5 bits (63), Expect = 0.029 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Query: 123 GEELTTREKGFKAVKEFLNEQLENIDLNYPNLVVAYEPIWAIGTKKSA 170 E TT K F +K+ LN +L N + N N + EPI+A KK A Sbjct: 855 QAEATTLSKNFSDIKKELNAKLGNFN-NNNNNGLKNEPIYAKVNKKKA 901
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1044 bits (2701), Expect = 0.0 Identities = 353/569 (62%), Positives = 443/569 (77%), Gaps = 4/569 (0%) Query: 3 KISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSN-NP 61 ++SR Y +M+GPT GDKVRL DT+L EVE D+T +GEE+KFGGGK +R+GM QS Sbjct: 4 RMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTR 63 Query: 62 SKEELDLIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEAL 121 +D +ITNALI+D+ GI KADIG+KDG+IA IGK GN DMQ GV + VGP TE + Sbjct: 64 EGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGV--TIIVGPGTEVI 121 Query: 122 AGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLKW 181 AGEG IVTAGG+D+HIHFI PQQI A SG+T M+GGGTGPA GT ATT TPG ++ Sbjct: 122 AGEGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIAR 181 Query: 182 MLRAAEEYSMNLGFLAKGNTSNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADKY 241 M+ AA+ + MNL F KGN S +L + + GA K+HEDWGTTP+AI+ L VAD+Y Sbjct: 182 MIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEY 241 Query: 242 DVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTN 301 DVQV IHTDTLNE+G VEDT+AAI GRT+H +HTEGAGGGHAPDII++ G+ N++P+STN Sbjct: 242 DVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTN 301 Query: 302 PTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSS 361 PT P+TVNT AEH+DMLMVCHHL +I ED+ FA+SRIR +TIAAED LHD+G FSI SS Sbjct: 302 PTRPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIISS 361 Query: 362 DSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISE 421 DSQAMGRVGEV RTWQTADK K++ GRLKEE GDNDNFR+KRY++KYTINPAIAHG+S Sbjct: 362 DSQAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSH 421 Query: 422 YVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAH 481 +GS+EVGK ADLVLW+PAFFGVKP+M++ GG IA + MGD NASIPTPQPV+YR MF Sbjct: 422 EIGSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGA 481 Query: 482 HGKAKYDANITFVSKAAYDKGIKEELGLERQVLPVKNCR-NITKKDMQFNDTTAHIEVNP 540 +G+++ ++++TFVS+A+ D G+ LG+ ++++ V+N R I K M N T HIEV+P Sbjct: 482 YGRSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDP 541 Query: 541 ETYHVFVDGKEVTSKPATKVSLAQLFSIF 569 ETY V DG+ +T +PAT + +AQ + +F Sbjct: 542 ETYEVRADGELLTCEPATVLPMAQRYFLF 570
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 24.1 bits (52), Expect = 0.039 Identities = 5/40 (12%), Positives = 16/40 (40%), Gaps = 1/40 (2%) Query: 19 NNENIQQSNADIYAITAK-VVLLENRLKKLQKEVAKLKQA 57 ++ ++ ++D+ I + + K L + K + Sbjct: 293 KSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDK 332
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 113 bits (283), Expect = 5e-29 Identities = 74/401 (18%), Positives = 154/401 (38%), Gaps = 29/401 (7%) Query: 54 KKPPESVLKNTLALDFCLNKFTKNAKILQANIIDNDRILEITGAKDLAYKSENFILRLEM 113 K P + + N N I + L + ++ ++ +N + L + Sbjct: 170 KLNPFDFSYDMIENFTKENSLQLNDNIFSKIFTGVSKTL----SSEICFRLKNNSIDLSL 225 Query: 114 IPKKANLMILDKEKCVIEA--FRFNDRVAKNDILGALPPN-TYEHQEEDLDFKGLLDILE 170 K + + I++ F FN N +G N + + + + +LE Sbjct: 226 SNLKEIVEVCKDLFKEIQSNKFEFNCYTKNNSFVGFYCLNLMSKEDYKKIQYDSSSKLLE 285 Query: 171 KDFLSYQHKE-LEHKKNQIIKRLNMQKERLKEKLEKLEDPKNLQLEAKELQTQASLLLTY 229 + + + L+ K + + K + R +K + L + + + LL Sbjct: 286 NFYYAKDKSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTAN 345 Query: 230 QHLINRHESCVVLKDFED---KECAIEIDKSMPLNAFINKKFTLSKKKKQKSQFLYLEEE 286 + + + S + L ++ I +D++ + + + K K+ + + Sbjct: 346 IYALKKGLSHIELANYYSENYDTVKITLDENKTPSQNVQSYYKKYNKLKKSEEAANEQLL 405 Query: 287 NLKEKIAFKENQINYVKGA---------KEESVLEMFM---PVKNSKIKRPMSGYEVLYY 334 +E++ + + + + A K+E + ++ + SK + + Sbjct: 406 QNEEELNYLYSVLTNINNADNYDEIEEIKKELIETGYIKFKKIYKSKKSKTSKPMHFISK 465 Query: 335 KDFKIGLGKNQKENVKL-LQDARANDLWMHVRDIPGSHLIVFCQKNTPKDEVIMELAKML 393 I +GKN +N L L+ A +D+W H ++IPGSH+IV + P + ++E A + Sbjct: 466 DGIDIYVGKNNIQNDYLTLKFANKHDIWFHTKNIPGSHVIVKNIMDIP-ESTLLEAANLA 524 Query: 394 IKMQKDVFNS-YEIDYTQRKFVRIIKGAN---VIYSKYRTI 430 K +S +DYT+ K V+ GA VIYS +TI Sbjct: 525 AYYSKSQNSSNVPVDYTEVKNVKKPNGAKPGMVIYSTNQTI 565 Score = 36.0 bits (83), Expect = 3e-04 Identities = 20/104 (19%), Positives = 51/104 (49%), Gaps = 7/104 (6%) Query: 36 KEKHAFVLDLN--TPYIGLSKKPPESVLKNTLALDFCLNKFTKNAKILQANIIDNDRI-- 91 + ++ + P I L+ + +K + L K+ NAKI+ + I+ DRI Sbjct: 43 RLSFKLLISSSSNYPRIHLTDLTKPNPIKAPMFCMV-LRKYISNAKIVDIHQINQDRIVV 101 Query: 92 LEITGAKDLAYKSENFILRLEMIPKKANLMILDK-EKCVIEAFR 134 ++ +L + S + L +E++ + +N+ ++ K + ++++ + Sbjct: 102 IDFESTDELGFNSI-YSLIIEIMGRHSNMTLIRKRDNIIMDSIK 144
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 90.7 bits (225), Expect = 3e-23 Identities = 38/224 (16%), Positives = 77/224 (34%), Gaps = 29/224 (12%) Query: 121 ESFKKDELDLSSVFEIQRKNTQMAYRLAIGGLIGVISLSVALAFLMPLKQIEPYFIDFAN 180 F++ ++ ++A+ +A + VA+A L PLK +EPY I Sbjct: 12 AYFEEAASWERDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDR 71 Query: 181 SDKYFAVVQRADTK--VDYGEAFLRNLVGSYITARETINHIDDKIRLNETIREQSSEEVW 238 + ++ + + Y EA + + +Y+ RE + + + S+ Sbjct: 72 NTGEASIAAKLHGDATITYDEAVRKYFLATYVRYREGWIAAAREEYF-DAVMVMSARPEQ 130 Query: 239 KTLEQLVSGKG-----SIYSNSNMDREIKIINISIYKQGKQQNIAVADIVAKVFDQGYLI 293 + +I +N D ++I +S + VA+V+ + Sbjct: 131 DRWSRFYKTDNPQSPQNILANRT-DVFVEIKRVSF----------LGGNVAQVYFTKESV 179 Query: 294 SEKRYRVSLIYHFKPLIQFDYSSMP-------KNPTGFIVDKYS 330 + S I++ P KNP G+ V+ Y Sbjct: 180 TGSN---STKTDAVATIKYKVDGTPSKEVDRFKNPLGYQVESYR 220
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.2 bits (70), Expect = 0.013 Identities = 30/158 (18%), Positives = 51/158 (32%), Gaps = 4/158 (2%) Query: 44 NAPTNNYNQPQETQPSTNYNTQPNSMQTPMPNQNHYSQPTTPIQNNQPNN----TQTQTM 99 N PT N +PQ +T QP + Q T N+ N T T Sbjct: 1149 NDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQ 1208 Query: 100 LNNAKQFTNNALNNTKQTITNATNYVNDKLTPKPNDVPISAFSANSPYANKENSKQTQKS 159 + +N N ++++ + + V T + ++ S N S K+ Sbjct: 1209 PTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKA 1268 Query: 160 DEVLSDDNSDEDNSLKPMTNFNAIQANFFAKNRSIKDN 197 V + + + N Q N + N S+ N Sbjct: 1269 QFVALNVGKAVSQHISQLEMNNEGQYNVWVSNTSMNKN 1306
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 33.1 bits (75), Expect = 0.004 Identities = 37/216 (17%), Positives = 75/216 (34%), Gaps = 26/216 (12%) Query: 530 EDAEIVSKEVGEFTRQSKNYSTEKGQLV---------FGGSSSYSHEGRSLLTAQDIMNI 580 ++AE K E ++ K EK + ++ S E +++ AQ ++ Sbjct: 141 KEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSA 200 Query: 581 NSDEVIVIVTGAKATPLKLKANYWFKDKELLKRANLPIDLEVERQRVEE----------- 629 EV+ + K +L ++ +D E+ A +L + +E Sbjct: 201 AQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPR 260 Query: 630 ---PIQPTTEIETTPNQNKADLEPSNKGEKVENESNERNTNENNPTTPQELENSNLKESE 686 P+Q E T + A K ++V N + T Q + + S Sbjct: 261 ANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINADITQIQ---KAISQVSN 317 Query: 687 KDNESPITLENANENIEQGNHNEIDEILKKPLSEIS 722 N + A EN+++ +N ++ +K + Sbjct: 318 NRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDATV 353
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 32.9 bits (75), Expect = 0.023 Identities = 45/235 (19%), Positives = 82/235 (34%), Gaps = 27/235 (11%) Query: 1257 EQDYKIIKDFIDKVGKNNINLNEQTLNEYFIHHPENILGHLSLEKTRHSFEINGEQIYKY 1316 ++ ++ KD ++ N N T N F+ L K + Y Sbjct: 229 KEIVEVCKDLFKEIQSNKFEFNCYTKNNSFVGFYCLNLMSKEDYKKIQYDSSSKLLENFY 288 Query: 1317 ELQA----LEDKSLDLSQALNQAIEKLPKGVYQYHKTTLKTDALIIDANNECYQEIQKLI 1372 + L+ KS DL + + I + K + T K + + + ++ +L+ Sbjct: 289 YAKDKSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCE------DKDIFKLYGELL 342 Query: 1373 K----NLERG-ELVKWDNLYFQLEQNNEIGIFLKPTKINSKVQDSRLKAYFKIKDALNDL 1427 L++G ++ N Y E + + I L K S+ S K Y K+K + Sbjct: 343 TANIYALKKGLSHIELANYY--SENYDTVKITLDENKTPSQNVQSYYKKYNKLKKSEEAA 400 Query: 1428 ------TSAELNPLSS---DLELESKRARLNLVYDEFVKKFGYLNENKNRKDIKQ 1473 ELN L S ++ + + E ++ GY+ K K K Sbjct: 401 NEQLLQNEEELNYLYSVLTNINNADNYDEIEEIKKELIET-GYIKFKKIYKSKKS 454
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 98.4 bits (245), Expect = 2e-26 Identities = 39/209 (18%), Positives = 77/209 (36%), Gaps = 16/209 (7%) Query: 87 EADVLFQAERKIGDWIFSSAVFFFALALIESIIICLLLPLKEKVPYLVTFSNATQNFAIV 146 E D L AER + A ALA + + L PLK PY++T T +I Sbjct: 21 ERDKLAAAERS-KKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIA 79 Query: 147 QR--ADKSIRANQALIRQLVASYVNNRE--NISNIKEQNEIAHETIRLQSTFEVWDFFEK 202 + D +I ++A+ + +A+YV RE + +E + + + S D + + Sbjct: 80 AKLHGDATITYDEAVRKYFLATYVRYREGWIAAAREEY----FDAVMVMSARPEQDRWSR 135 Query: 203 LVSYEH-----SIYTNINLTRKISIINIALISKTQANIEISAQLFNKEKLESEKRYRIIM 257 ++ +I N + I ++ + A + + + ++ + Sbjct: 136 FYKTDNPQSPQNILAN-RTDVFVEIKRVSFLGGNVAQVYFT-KESVTGSNSTKTDAVATI 193 Query: 258 TFEFEPIEIDTKSVPLNPTGFIVTGYDVT 286 ++ + NP G+ V Y Sbjct: 194 KYKVDGTPSKEVDRFKNPLGYQVESYRAD 222
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.0 bits (109), Expect = 1e-07 Identities = 56/271 (20%), Positives = 105/271 (38%), Gaps = 16/271 (5%) Query: 28 LILSGSLTPNQSFQLGIAVLMGYVFGSFLIQFLSPLMSLESIAKISFFLIALSFLICYFD 87 L+ S +T + L + LM + L LS + +S A+ + I Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGA-LSDRFGRRPVLLVSLAGAAVDYAI--MA 91 Query: 88 SIPFFW-LWIWRFIAGVASSALMILVAPLSLPYVKENKRALVGGFIFSAVGIGSVFSGFV 146 + PF W L+I R +AG+ + A + ++RA GF+ + G G V + Sbjct: 92 TAPFLWVLYIGRIVAGI-TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVL 150 Query: 147 LPWISSYNIKWAWIFLGGSCLIAFILSLIGLKN-HSLKKKSVKKEEGAFKIPFHL----- 200 + ++ + + F+ L H +++ +++E F Sbjct: 151 GGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMT 210 Query: 201 ---WLLLISCALNAIGFLPHTLFWVDYLIRHLNISPTTAGTSWALFG-FGATLGSLISGP 256 L+ + + +G +P L WV + + TT G S A FG + ++I+GP Sbjct: 211 VVAALMAVFFIMQLVGQVPAAL-WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 257 MAQKLGAKNANIFILILKSIACFLPIFFHQI 287 +A +LG + A + +I L F + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRG 300
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.019 Identities = 9/18 (50%), Positives = 11/18 (61%) Query: 8 LILSGPSGSGKSTLTKYL 25 ++L G G GKSTL L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 60.5 bits (146), Expect = 9e-12 Identities = 52/274 (18%), Positives = 96/274 (35%), Gaps = 20/274 (7%) Query: 142 ENLGDLEALVQEEPNNEEQL--LPTLNDQKEKEEGKEEEKEEVKEEEKEEVKETPQEEEK 199 +++A V P+N E++ + E E V E K+E K + E+ Sbjct: 998 TTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQD 1057 Query: 200 PKDNEIQEGETQKNEEVSKELETQEELEIPKEETQEIKEEKQEKTQEQAKE-QEPIKEET 258 + Q E K + + + TQ E+ + ++ + + E + E +E K ET Sbjct: 1058 ATETTAQNREVAKEAKSNVKANTQT-NEVAQSGSETKETQTTETKETATVEKEEKAKVET 1116 Query: 259 QENKEKKQEKTQDSPSAQELEAMQ------------ELVKEIQENSNGQED----KKETQ 302 ++ +E + +Q SP ++ E +Q +KE Q +N D KET Sbjct: 1117 EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETS 1176 Query: 303 ENTETPQEKEKQELETQEKTQESAETPQEKTQKLEAQKDHYESIEDIPEPVMAQAMGEEL 362 N E P + + T TQ + + V + E Sbjct: 1177 SNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEP 1236 Query: 363 PFLNESVAKTSNNKNDTETPKESVIKTPQEKEES 396 + + T + T T +V+ + K + Sbjct: 1237 ATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQF 1270 Score = 57.4 bits (138), Expect = 7e-11 Identities = 41/217 (18%), Positives = 70/217 (32%), Gaps = 14/217 (6%) Query: 185 EEKEEVKETPQEEEKPKDNEIQEGETQKNEEVSKELETQEELEIPKEETQEIKEEKQEKT 244 E++ + +T NEE+++ E P + +T Sbjct: 986 EKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPS---------ET 1036 Query: 245 QEQAKEQEPIKEETQENKEKKQEKTQDSPSAQELEAMQELVKEIQENSNGQEDKKETQEN 304 E E + +T E E+ +T EA + Q N Q + Sbjct: 1037 TETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQS--GSETKE 1094 Query: 305 TETPQEKEKQELETQEKTQESAETPQEKTQKLEAQKDHYESIEDIPEPVMAQAMGEELPF 364 T+T + KE +E +EK + E QE + E E + A+ E P Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETV--QPQAEPARENDPT 1152 Query: 365 LNESVAKTSNNKN-DTETPKESVIKTPQEKEESDKTS 400 +N ++ N DTE P + ++ T Sbjct: 1153 VNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTV 1189
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 192 bits (489), Expect = 9e-64 Identities = 52/172 (30%), Positives = 84/172 (48%), Gaps = 18/172 (10%) Query: 56 GERPLFADRRAMKPNDLITIIVSEKASANYSSS----KDYKSASGGNSTPPRLTYNGLDE 111 G +PLF DRR D +TI++ E SA+ SSS +D K+ G ++ P L GL Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYL--QGLFG 118 Query: 112 RKRKEAQYLDDKNNYNFTKSSNNTNFKGGGSQKKSEDLEIVLSARIIKVLENGNYFIYGN 171 R + + S F G G S L+ + +VL NGN + G Sbjct: 119 NARADVEA------------SGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGE 166 Query: 172 KEVLVDGEKQILKVSGVIRPYDIERNNTIQSKFLADAKIEYTNLGHLSDSNK 223 K++ ++ + ++ SGV+ P I +NT+ S +ADA+IEY G+++++ Sbjct: 167 KQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN 218
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.017 Identities = 15/49 (30%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 102 RGETILKALERIAFE---EFQLNSLHLEVMENNFKAIAFYEKNHYELEG 147 R + + AL A E E L LE + N A FY K+H+ + Sbjct: 102 RKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 27.8 bits (62), Expect = 0.022 Identities = 16/58 (27%), Positives = 23/58 (39%), Gaps = 6/58 (10%) Query: 32 FVIVAWLFRF--KSIAFSILITLLVILVDIWVYSDVRQFLLDTARSPILLLAALLIKW 87 V VA ++A +L +LV L I D+ + LL + LL LL Sbjct: 121 SVAVAMTLAPGWGTLAALLLTWVLVALTFI----DLDKMLLPDQLTLPLLWGGLLFNL 174
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 196 bits (501), Expect = 4e-57 Identities = 115/461 (24%), Positives = 190/461 (41%), Gaps = 67/461 (14%) Query: 3 NIRNIAVIAHVDHGKTTLVDGLLSQSGTFSEREKVDE--RVMDSNDLERERGITILSKNT 60 I NI V+AHVD GKTTL + LL SG +E VD+ D+ LER+RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 61 AIYYKDTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALSFGI 120 + +++TK+NIIDTPGH DF EV R L ++DG +LL+ A++GV QT+ + GI Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 121 CPIVVVNKIDKPAAEPDRVVDEVFDLF---------VAMGASDKQLDFPV-----VYAAA 166 I +NKID+ + V ++ + V + + +F Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 167 RDGYAMKSLDDE----------------------------KKNL--EPLFETILEHVPSP 196 D K + + K N+ + L E I S Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSS 241 Query: 197 SGSVDEPLQMQIFTLDYDNYVGKIGIARVFNGSVKKSESVLLMKSDGSKENGRITKLIGF 256 + L ++F ++Y ++ R+++G + +SV + KE +IT++ Sbjct: 242 THRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRI----SEKEKIKITEMYTS 297 Query: 257 LGLARTEIENAYAGDIVAIAG--FSAMDV-GDSVVDPANPMPLDPMHLEEPTMSVYFAVN 313 + +I+ AY+G+IV + V GD+ + P +P P + + Sbjct: 298 INGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENP----LPLLQTTVEPS 353 Query: 314 DSPLAGLEGKHVTANKLKDRLLKEMQTNIAMKCEEMGEGKFKVSGRGELQITILAENLRR 373 + + D LL+ + + +S G++Q+ + L+ Sbjct: 354 KPQQREMLLDALLEISDSDPLLRYYVDSAT--------HEIILSFLGKVQMEVTCALLQE 405 Query: 374 E-GFEFSISRPEVIIKEENGVKCEPFEHLVIDTPQDFSGAI 413 + E I P VI E K E H+ + P F +I Sbjct: 406 KYHVEIEIKEPTVIYMERPLKKAEYTIHIEVP-PNPFWASI 445 Score = 41.8 bits (98), Expect = 8e-06 Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 1/80 (1%) Query: 396 EPFEHLVIDTPQDFSGAIIERLGKRKAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLT 455 EP+ I PQ++ K A + + + L EIPAR + YRS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRSDLTF 595 Query: 456 DTKGEGVMNHSFLEFRPFSG 475 T G V + +G Sbjct: 596 FTNGRSVCLTELKGYHVTTG 615
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 30.5 bits (69), Expect = 0.016 Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 13/60 (21%) Query: 271 GNVVTKEATSDLISAGADAIKVGIGPGSICTTRIVAGVGMPQVSAIDNCVEVASKFDIPV 330 GN A +++ GA ++K+ G+ P +AID C+ VA ++D+ V Sbjct: 199 GNASLPGALVEMVLGGATSLKLHEDWGT-----------TP--AAIDCCLSVADEYDVQV 245
>adhesinb#Adhesin B signature. Length = 310 Score = 27.5 bits (61), Expect = 0.011 Identities = 18/83 (21%), Positives = 28/83 (33%), Gaps = 10/83 (12%) Query: 22 FLKTLGFEMVERNFFSKFGEI-------DIIAFKKGV--LHFIEVKSGENFDPIYAITPS 72 F + E +F+K E D A +GV ++ DP + Sbjct: 87 FYNGINLETGGNAWFTKLVENAKKKENKDYYAVSEGVDVIYLEGQSEKGKEDPHAWLNLE 146 Query: 73 KLKKMIKTIRCYLSQKDP-NSDF 94 + I LS+KDP N + Sbjct: 147 NGIIYAQNIAKRLSEKDPANKET 169
>PF07132#Harpin protein (HrpN) Length = 356 Score = 26.2 bits (57), Expect = 0.031 Identities = 13/35 (37%), Positives = 17/35 (48%) Query: 31 GQHGRDIGGAVGGYLGRNGGLLGAVGGYLLGQEIG 65 G +GG +GG GGL G + G LG +G Sbjct: 63 SMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLG 97
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 276 bits (708), Expect = 2e-96 Identities = 113/245 (46%), Positives = 162/245 (66%), Gaps = 2/245 (0%) Query: 1 MRFFIFLILICPLICPLMSADSALPSVNLSLNAPNDPKQLVTTLNVIALLTLLVLAPSLI 60 MR + + + L A + LP + S P + + + +T L P+++ Sbjct: 1 MRRLLSVAPVL-LWLITPLAFAQLPGIT-SQPLPGGGQSWSLPVQTLVFITSLTFIPAIL 58 Query: 61 LVMTSFTRLIVVFSFLRTALGTQQTPPTQILVSLSLILTFFIMEPSLKKAYDTGIKPYMD 120 L+MTSFTR+I+VF LR ALGT PP Q+L+ L+L LTFFIM P + K Y +P+ + Sbjct: 59 LMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSE 118 Query: 121 KKISYTEAFEKSALPFKEFMLKNTREKDLALFFRIRNLPNPKTPDEVSLSVLIPAFMISE 180 +KIS EA EK A P +EFML+ TRE DL LF R+ N + P+ V + +L+PA++ SE Sbjct: 119 EKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSE 178 Query: 181 LKTAFQIGFLLYLPFLVIDMVISSILMAMGMMMLPPVMISLPFKILVFILVDGFNLLTEN 240 LKTAFQIGF +++PFL+ID+VI+S+LMA+GMMM+PP I+LPFK+++F+LVDG+ LL + Sbjct: 179 LKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGS 238 Query: 241 LVASF 245 L SF Sbjct: 239 LAQSF 243
>PF01206#SirA family protein Length = 76 Score = 26.6 bits (59), Expect = 0.004 Identities = 7/22 (31%), Positives = 12/22 (54%) Query: 19 SGKEIEVLSTKPEMRIDISSFC 40 +G+ + V++T P D SF Sbjct: 31 AGEVLYVMATDPGSVKDFESFS 52
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 1716 bits (4445), Expect = 0.0 Identities = 926/1191 (77%), Positives = 1021/1191 (85%), Gaps = 60/1191 (5%) Query: 1 MTNETIDQTPTPDQTPNQTDFVPQRFINNLQVAFIKVDNAVASFDPDQKPIVDKNDRDNR 60 MTNETIDQ P + F PQ+FINNLQVAF+KVDNAVAS+DPDQKPIVDKNDRDNR Sbjct: 1 MTNETIDQQPQ-----TEAAFNPQQFINNLQVAFLKVDNAVASYDPDQKPIVDKNDRDNR 55 Query: 61 QAFEKISQLREEYANKAIKNPAKKNQYFSDFINKSNDLINKDNLIAVDSSVESFKKFGDQ 120 QAFE ISQLREEY+NKAIKNP KKNQYFSDFINKSNDLINKDNLI V+SS +SF+KFGDQ Sbjct: 56 QAFEGISQLREEYSNKAIKNPTKKNQYFSDFINKSNDLINKDNLIDVESSTKSFQKFGDQ 115 Query: 121 RYQIFTSWVSLQKDPSKINTQQIQNFMENIIQPPISDDKEKAEFLRSAKQSFAGIIIGNQ 180 RY+IFTSWVS Q DPSKINT+ I+NFMENIIQPPI DDKEKAEFL+SAKQSFAGIIIGNQ Sbjct: 116 RYRIFTSWVSHQNDPSKINTRSIRNFMENIIQPPILDDKEKAEFLKSAKQSFAGIIIGNQ 175 Query: 181 IRSDQKFMGVFDESLKERQEAEKNAEPAGGDWLDIFLSFVFNKKQSSDLKETLHQEPRPD 240 IR+DQKFMGVFDESLKERQEAEKN EP GGDWLDIFLSF+F+KKQSSD+KE ++QEP P Sbjct: 176 IRTDQKFMGVFDESLKERQEAEKNGEPTGGDWLDIFLSFIFDKKQSSDVKEAINQEPVPH 235 Query: 241 FEQNLATTTTNIQGLPPEARDLLDERGNFFKFTLGDVEMLDVEGVADKDPNYKFNQLLIH 300 + ++ATTTT+IQGLPPEARDLLDERGNF KFTLGD+EMLDVEGVAD DPNYKFNQLLIH Sbjct: 236 VQPDIATTTTDIQGLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIH 295 Query: 301 NNALSSVLMGSHSNIEPEKVSLLYGDNGGPEARHDWNATVGYKDQQGNNVATLINAHLNN 360 NNALSSVLMGSH+ IEPEKVSLLYG NGGP ARHDWNATVGYKDQQGNNVAT+IN H+ N Sbjct: 296 NNALSSVLMGSHNGIEPEKVSLLYGGNGGPGARHDWNATVGYKDQQGNNVATIINVHMKN 355 Query: 361 GSGLIIAGNENGIKNPSFYLYKEDQLTGLKQAMSQEEIQNKVDFMEFLAKNNAKLDNLSK 420 GSGL+IAG E GI NPSFYLYKEDQLTG ++A+SQEEIQNK+DFMEFLA+NNAKLDNLS+ Sbjct: 356 GSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIQNKIDFMEFLAQNNAKLDNLSE 415 Query: 421 EEKEKFQTEIGNFQKDRKAYLDALGNDHIAFVSKKDSKHLALVTEFGNGEVSYTLKDYGK 480 +EKEKF+TEI +FQKD KAYLDALGND IAFVSKKD+KH AL+TEFGNG++SYTLKDYGK Sbjct: 416 KEKEKFRTEIKDFQKDSKAYLDALGNDRIAFVSKKDTKHSALITEFGNGDLSYTLKDYGK 475 Query: 481 KQDKALDGETKTTLQGSLKYDGVMFVNYSNFKYTNASKSPDKGVGTTNGVSHLEANFSKV 540 K DKALD E TLQGSLK+DGVMFV+YSNFKYTNASK+P+KGVG TNGVSHLE F+KV Sbjct: 476 KADKALDREKNVTLQGSLKHDGVMFVDYSNFKYTNASKNPNKGVGVTNGVSHLEVGFNKV 535 Query: 541 AVFNLPNLNNLAITNYIRRDLEDKLLAKGLSPQEANKLIKDFLNSNKELVGKVSNFNKAV 600 A+FNLP+LNNLAIT+++RR+LEDKL KGLSPQEANKLIKDFL+SNKELVGK NFNKAV Sbjct: 536 AIFNLPDLNNLAITSFVRRNLEDKLTTKGLSPQEANKLIKDFLSSNKELVGKTLNFNKAV 595 Query: 601 AEAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVAKKLESRNDNKNRMEAKAQANSQKDKI 660 A+AKNTGNYDEVKKAQKDLEKSLRKREHLEKEV KKLES++ NKN+MEAKAQANSQKD+I Sbjct: 596 ADAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNKMEAKAQANSQKDEI 655 Query: 661 FALINKEASKEARAAAFDPNLKGVRSELSDKLENINKNLKDFGKSFDELKNGKNNDFSKA 720 FALINKEA+++ARA A+ NLKG++ ELSDKLEN+NKNLKDF KSFDE KNGKN DFSKA Sbjct: 656 FALINKEANRDARAIAYAQNLKGIKRELSDKLENVNKNLKDFDKSFDEFKNGKNKDFSKA 715 Query: 721 EETLKALKDSVKDLGINPEWISKIENLNAALNDFKNGKNKDFSKVTQAKSDLENSIKDVI 780 EETLKALK SVKDLGINPEWISK+ENLNAALN+FKNGKNKDFSKVTQAKSDLENS+KDVI Sbjct: 716 EETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVI 775 Query: 781 INQKITDKVDNLNQAVSETKLTGDFSKVEQALAELKSLS-------------LDLGKNSD 827 INQK+TDKVDNLNQAVS K TGDFS+VEQALA+LK+ S L+ K S+ Sbjct: 776 INQKVTDKVDNLNQAVSVAKATGDFSRVEQALADLKNFSKEQLAQQAQKNESLNARKKSE 835 Query: 828 L-QSVKNSVNGTLVGNGLSKTEATTLTKNFSDIRKELNEKLFGNSNNNNNGLKNNTEPIY 886 + QSVKN VNGTLVGNGLS+ EATTL+KNFSDI+KELN KL +NNNNNGLKN EPIY Sbjct: 836 IYQSVKNGVNGTLVGNGLSQAEATTLSKNFSDIKKELNAKLGNFNNNNNNGLKN--EPIY 893 Query: 887 AQVNKKKAGQATSPEEPIYAQVAKKVSAKIDQLNEATSAINRKIDRINKIASAGKGVGGF 946 A+VNKKKAGQA S EEPIYAQVAKKV+AKID+LN+ S G GV G Sbjct: 894 AKVNKKKAGQAASLEEPIYAQVAKKVNAKIDRLNQIAS---------------GLGVVG- 937 Query: 947 SGAGRSASPEPIYATIDFDEANQAGFPLRRSAAVNDLSKVGLSREQELTRRIGDLNQAVS 1006 AGFPL+R V+DLSKVGLSR QEL ++I +LNQAVS Sbjct: 938 ---------------------QAAGFPLKRHDKVDDLSKVGLSRNQELAQKIDNLNQAVS 976 Query: 1007 EAKTGHFGNLEQKIDELKDSTKKNALKLWVESAKQVPTGLQAKLDNYATNSHTRINSNVQ 1066 EAK G FGNLEQ ID+LKDSTK N + LWVESAK+VP L AKLDNYATNSH RINSN++ Sbjct: 977 EAKAGFFGNLEQTIDKLKDSTKHNPMNLWVESAKKVPASLSAKLDNYATNSHIRINSNIK 1036 Query: 1067 SGTINEKATGMLTQKNPEWLKLVNDKIVAHNVGSAHLSEYDKIGFNQKNMKDYSDSFKFS 1126 +G INEKATGMLTQKNPEWLKLVNDKIVAHNVGS LSEYDKIGFNQKNMKDYSDSFKFS Sbjct: 1037 NGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNMKDYSDSFKFS 1096 Query: 1127 TKLNNAVKDIKSSFVQFLTNTFSTGS-YSLMKANVEHGVKNT-TKSGFQKS 1175 TKLNNAVKD S F QFLTN FST S Y L + N EHG+KN TK GFQKS Sbjct: 1097 TKLNNAVKDTNSGFTQFLTNAFSTASYYCLARENAEHGIKNVNTKGGFQKS 1147
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 32.9 bits (75), Expect = 0.008 Identities = 20/88 (22%), Positives = 32/88 (36%), Gaps = 18/88 (20%) Query: 19 EVQKRQFQKIEELKADMQKGVNPFFKVLFDGGNRLFGFPETFIYSSI-------FILFVT 71 + K K+ EL+ +G+ +D F+ SI F + Sbjct: 301 DTAKAIKAKLAELQPFFPQGMK--VLYPYD--------TTPFVQLSIHEVVKTLFEAIML 350 Query: 72 IVLSVILF-QAYEPVLIVAIVIVLVALG 98 + L + LF Q LI I + +V LG Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLG 378
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 30.5 bits (68), Expect = 0.008 Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 16/119 (13%) Query: 24 AINTALLPSEYKKLVALGFKKIKTFHQRHDEKEVTEEEKEFATNALREKLRNDRARAEQI 83 A+N AL+ +Y++ + K K D KE+ E++K EK + + +A++ Sbjct: 112 AVNFALMTRDYQEFL----KTKKLIVDAPDPKELEEQKKAL------EKEKEAKEQAQKA 161 Query: 84 QKNIEAFEKKNNSSIQKKAAKHKGLQELNETNANPLNDNPNSNSSTENKSNKDDNFDEM 142 QK+ K +++A L+ L +NP N + N N S K +++ D+M Sbjct: 162 QKD------KREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQM 214
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 119 bits (299), Expect = 5e-35 Identities = 44/205 (21%), Positives = 74/205 (36%), Gaps = 10/205 (4%) Query: 27 KLNKANRTFKRAFYL---SMALNIAAVTSIVMMMPLKKTDIFVYGIDRYTGEFKIVKRSD 83 KL A R+ K A+ + + AL A V ++ + PLK + +V +DR TGE I + Sbjct: 24 KLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAKLH 83 Query: 84 A-RQIVNSEAVVDSATSKFVSLLFGYSKNSLRDRKDQLMQYCDVSFQTQAMRMFNENIRQ 142 I EAV + +V G+ + + D +M Q + R + + Q Sbjct: 84 GDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARPEQDRWSRFYKTDNPQ 143 Query: 143 FVDKVRA-EAIISSNIQREKVKNSPLTRLTFFITIKITPDTMENYEYITKKQVTIYYDFA 201 + A + I + +F +T T TI Y Sbjct: 144 SPQNILANRTDVFVEI-KRVSFLGGNVAQVYFTKESVTGSNS----TKTDAVATIKYKVD 198 Query: 202 RGNSSQENLIINPFGFKVFDIQITD 226 S + + NP G++V + Sbjct: 199 GTPSKEVDRFKNPLGYQVESYRADV 223
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 865 bits (2235), Expect = 0.0 Identities = 514/522 (98%), Positives = 515/522 (98%), Gaps = 1/522 (0%) Query: 1 MEQAFFKKIVGCFCLGYLFLSSVIEAAP-DIKNFNRGRVKVVNKKIAYLGDEKPITIWTS 59 M QAFFKKIVGCFCLGYLFLSS IEA DIKNFNRGRVKVVNKKIAYLGDEKPITIWTS Sbjct: 1 MGQAFFKKIVGCFCLGYLFLSSAIEAVALDIKNFNRGRVKVVNKKIAYLGDEKPITIWTS 60 Query: 60 LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR 119 LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR Sbjct: 61 LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR 120 Query: 120 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANL 179 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANL Sbjct: 121 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANL 180 Query: 180 ENLTNAMSNPQNLSNNKNLSEFIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA 239 ENLTNAMSNPQNLSNNKNLSE IKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA Sbjct: 181 ENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA 240 Query: 240 EEAVKQRAKDKISIKTDKPQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD 299 EEAV+QRAKDKISIKTDK QKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD Sbjct: 241 EEAVRQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD 300 Query: 300 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNE 359 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNE Sbjct: 301 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNE 360 Query: 360 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF 419 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF Sbjct: 361 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF 420 Query: 420 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK 479 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK Sbjct: 421 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK 480 Query: 480 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK 521 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK Sbjct: 481 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK 522
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 43.9 bits (103), Expect = 8e-06 Identities = 40/230 (17%), Positives = 87/230 (37%), Gaps = 11/230 (4%) Query: 583 TPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDC 642 P ++ + + ++KT + ++ T + ++ +EAK +VKA Sbjct: 1023 APVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT 1082 Query: 643 VSQAKTEAEKKECEKLLTPEAKKLLEQQALDCLKSAKTDEERKKCLKDLPKDLQKKVL-- 700 A++ +E KE + T E +E++ +++ KT E K + PK Q + + Sbjct: 1083 NEVAQSGSETKETQTTETKETAT-VEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQP 1141 Query: 701 ----AKESVKAYL--DCVSQAKTEAEKKECEKLLTPEARKLLEEAKESLKAYKDCVSRAR 754 A+E+ + SQ T A+ ++ K + + + E+ + V Sbjct: 1142 QAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTG--NSVVENP 1199 Query: 755 NEKEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKL 804 + + E+ + + SV++ V A T + + L Sbjct: 1200 ENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVAL 1249 Score = 38.9 bits (90), Expect = 2e-04 Identities = 31/196 (15%), Positives = 77/196 (39%), Gaps = 6/196 (3%) Query: 676 KSAKTDEERKKCLKDLP-KDLQKKVLAKESVKAYLDCVSQAKTEAEKKECEKLLTPEARK 734 S ++ E + + P ++ + + ++KT + ++ T + R+ Sbjct: 1008 PSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNRE 1067 Query: 735 LLEEAKESLKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKT 794 + +EAK ++KA A++ E KE + T E K+ E +E K + + Sbjct: 1068 VAKEAKSNVKANTQTNEVAQSGSETKETQ---TTETKETATVEKEEKAKVETEKTQEVPK 1124 Query: 795 EAEKKECEKLLTPEAKKKLEEAKKSVKAYL--DCVSQAKTEAEKKECEKLLTPEAKNLLE 852 + ++ + + + E A+++ + SQ T A+ ++ K + + + Sbjct: 1125 VTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVT 1184 Query: 853 QQALDCLKNAKTESEK 868 + N+ E+ + Sbjct: 1185 ESTTVNTGNSVVENPE 1200 Score = 36.6 bits (84), Expect = 0.001 Identities = 32/173 (18%), Positives = 67/173 (38%), Gaps = 21/173 (12%) Query: 767 TPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDC 826 P ++ + + ++KT + ++ T + ++ +EAK +VKA Sbjct: 1023 APVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT 1082 Query: 827 VSQAKTEAEKKECEKLLTPEAKNLLEQQALDCLKNAKTESEKKRCVKDLPKDLQKKVLAK 886 A++ +E KE + T E + +++ AK E+EK + V KV ++ Sbjct: 1083 NEVAQSGSETKETQTTETKETATVEKEE------KAKVETEKTQEV--------PKVTSQ 1128 Query: 887 ESVKAYLDCVSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSQAKT 939 S K + ++E + + E + ++E + D AK Sbjct: 1129 VSPK-------QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKE 1174 Score = 33.5 bits (76), Expect = 0.011 Identities = 26/177 (14%), Positives = 66/177 (37%), Gaps = 4/177 (2%) Query: 499 RARNEKEKKECEKLLTPEAKKKLEQQVLDCLKNAKTDEERKKCLKDLPKD--LQSDILAK 556 + NE+ + E + P A + +N+K + + + + + Q+ +AK Sbjct: 1011 PSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAK 1070 Query: 557 ESLKAYKDCVSQAKTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKE 616 E+ K + E ++ T E K+ E +E K + + + Sbjct: 1071 EAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVS 1130 Query: 617 CEKLLTPEAKKKLEEAKKSVKAYL--DCVSQAKTEAEKKECEKLLTPEAKKLLEQQA 671 ++ + + + E A+++ + SQ T A+ ++ K + ++ + + Sbjct: 1131 PKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTEST 1187
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 30.2 bits (68), Expect = 0.017 Identities = 14/76 (18%), Positives = 26/76 (34%), Gaps = 15/76 (19%) Query: 277 APENSKEKLIEELIANSQLIANEEEREKKLLAEKERQ--------EAELAKY--KLKDLE 326 S + EE+ E +E L K E ++ +Y K+ +LE Sbjct: 44 GTLQSIADMAEEVTF-----VFSERKELSLDKRKLSDSQARVSDVEEQVNQYLSKVPELE 98 Query: 327 NQKKLKALEAELKKKN 342 ++ + L + L Sbjct: 99 QKQNVSELLSLLSNSP 114
>PF05211#Neuraminyllactose-binding hemagglutinin Length = 260 Score = 262 bits (671), Expect = 4e-90 Identities = 63/268 (23%), Positives = 118/268 (44%), Gaps = 39/268 (14%) Query: 18 KTLISLGISSVLVGCTIKPVAEVKPQNQQEKPIQVNEKIQTTQKVTPFNFNYSLHVAQAA 77 K L+ + ++LVGC+ I+T + N+ + A Sbjct: 14 KCLLGASVVALLVGCS-------------------PHIIETNEVALKLNY-HPASEKVQA 53 Query: 78 QNYRLIGILAPRIQVSDNL-KPYIDKFQDALINQIQTIFEKRGYQTL--FLKDESALTLQ 134 + + I +L P Q SDN+ K Y +KF++ +++ I + +GY+ + D+ + Sbjct: 54 LDEK-ILLLRPAFQYSDNIAKEYENKFKNQTTLKVEQILQNQGYKVINVDSSDKDDFSFA 112 Query: 135 DKRKLFAVLDVKGWVGVLEDLKMNLKDPNNPNL--GTLVDQ------SSGSVWFSFYEPE 186 K++ + + + G + + D K ++ + P L T +D+ +G V + EP Sbjct: 113 QKKEGYLAVAMNGEIVLRPDPKRTIQKKSEPGLLFSTGLDKMEGVLIPAGFVKVTILEPM 172 Query: 187 SNRVVHDFAVEVGTF---QAMTYTYKQSNSGGFNSSNSIIHEDLEKNKEDAIHQILNKIY 243 S + F +++ + T S+SGG S+ N DAI LNKI+ Sbjct: 173 SGESLDSFTMDLSELDIQEKFLKTTHSSHSGGLVSTMV----KGTDNSNDAIKSALNKIF 228 Query: 244 ALIMKKAVTELTEKNISQYKEAIDRMKG 271 A IM++ +LT+KN+ Y++ +KG Sbjct: 229 ANIMQEIDKKLTQKNLESYQKDAKELKG 256
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 28.9 bits (64), Expect = 0.012 Identities = 13/33 (39%), Positives = 22/33 (66%) Query: 80 IENIFANEKEDTTYIITSYLNKEELFEKKPELK 112 + N+ A+EK D ++++ L+ E FEK PE+K Sbjct: 314 VGNLGASEKSDVFLVVSTLLHCIEGFEKNPEIK 346
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 146 bits (370), Expect = 2e-45 Identities = 45/168 (26%), Positives = 71/168 (42%), Gaps = 22/168 (13%) Query: 22 NMDKETVAGDVSAKTVQSAPVSTETAQEKQEPKQEPAPVVEEKPAIESGTIIASIYFDFD 81 D ++ VS + Q P PAP V+ K T+ + + F+F+ Sbjct: 177 RPDNGMLSLGVSYRFGQGEAA----PVVAPAP--APAPEVQTK----HFTLKSDVLFNFN 226 Query: 82 KYEIKESDQETLDEIVQKAKE---NHMQVLLEGNTDEFGSSEYNQALGVKRTLSVKNALV 138 K +K Q LD++ + V++ G TD GS YNQ L +R SV + L+ Sbjct: 227 KATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLI 286 Query: 139 IKGVEKDMIKTISFGETKPKCTQ-----KTR----ECYRENRRVDVKL 177 KG+ D I GE+ P K R +C +RRV++++ Sbjct: 287 SKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 32.0 bits (72), Expect = 0.003 Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 11/142 (7%) Query: 32 EEAEKILLDLGKKNEQVID--LNLEDLPSDEKKEEKVEE-KKDEKVVEKNATDKEGDFID 88 +EA K++ D N++++ LN +D K +E KK +K +EK+ +E Sbjct: 568 QEANKLIKDFLSSNKELVGKTLNFNKAVADAKNTGNYDEVKKAQKDLEKSLRKREHL--- 624 Query: 89 PKEQEESLENIFSSLNDFQEKTDTNAQKDE----QKNEQEEEQRRLKEQQRLRKNQKN-Q 143 KE E+ LE+ + N + K N+QKDE E + R + Q L+ ++ Sbjct: 625 EKEVEKKLESKSGNKNKMEAKAQANSQKDEIFALINKEANRDARAIAYAQNLKGIKRELS 684 Query: 144 EMLKGLQQNLDQFAQKLESVKN 165 + L+ + +NL F + + KN Sbjct: 685 DKLENVNKNLKDFDKSFDEFKN 706
>PF07675#Cleaved Adhesin Length = 1358 Score = 32.8 bits (74), Expect = 0.002 Identities = 30/105 (28%), Positives = 40/105 (38%), Gaps = 7/105 (6%) Query: 70 QISQVILKTQMPFLDLVPSNLGLAGFEKTFYESQDKNKRGELMLKNALESVV---GLYDY 126 VI T F SNL A FE + D + ++ VV G+YDY Sbjct: 414 TFGSVIPATGPLFTGTASSNLYSANFEYLTPANADPVVTTQNIIVTGQGEVVIPGGVYDY 473 Query: 127 IIIDSPPALGPLTINSLSAAHSVIIPIQCEFFALEGTKLLLNTIR 171 I + PA G + I A P + + FA E K T+R Sbjct: 474 CITNPEPASGKMWI----AGDGGNQPARYDDFAFEAGKKYTFTMR 514
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 43.1 bits (101), Expect = 2e-06 Identities = 33/230 (14%), Positives = 73/230 (31%), Gaps = 19/230 (8%) Query: 5 QTRPFICPNCQEPIDVNEALYKQIEQENQSRFLAQQKAFEKEVKEKRA--QYQSHFKA-- 60 P P P + E + + +QE+++ +Q A E + + + +S+ KA Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 61 -------LEQKEEALKEREKEQKAQFDDAVKQASVLALQDERAKIIEEA---RKNAFLEQ 110 + + + E ++ A + K E K+ + ++ + Q Sbjct: 1081 QTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQ 1140 Query: 111 QKGLELLQKELDEKSKQVQELHQKEAEIERLKRENNEAESRLKAEN--EKKLNEKLETEK 168 + + + K+ Q A+ E+ +E + + E+ N +E + Sbjct: 1141 PQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPE 1200 Query: 169 ERIEKALHEK--NELKFKQQEEQLEMLRNELKNAQRKAELSSQQFQGEVQ 216 +E K + +R+ N A SS Sbjct: 1201 NTTPATTQPTVNSESSNKPKNRHRRSVRSVPHN-VEPATTSSNDRSTVAL 1249 Score = 33.9 bits (77), Expect = 0.001 Identities = 27/194 (13%), Positives = 54/194 (27%), Gaps = 14/194 (7%) Query: 29 EQENQSRFLAQQKAFEKEVKEKRAQYQSHFKALEQKEEALKEREKEQKAQFDDAVKQASV 88 E ++Q++ E E+ A + +E KE K+ + V Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDA---------TETTAQNREVAKEAKSNVKANTQTNEV 1085 Query: 89 LALQDERAKIIEEARKNAFLEQQKGLELLQKELDEKSKQVQELHQKEAEIERLKRENNEA 148 E E E K EK+++V + + ++ + E + Sbjct: 1086 AQSGSE---TKETQTTETKETATVEKEEKAKVETEKTQEVPK-VTSQVSPKQEQSETVQP 1141 Query: 149 ESRLKAENEKKLNEKLETEKERIEKALHEKNELKFKQQEEQLEMLRNELKNAQRKAELSS 208 ++ EN+ +N K + + + + EQ + E Sbjct: 1142 QAEPARENDPTVNIKEPQSQTNTTADTEQPAK-ETSSNVEQPVTESTTVNTGNSVVENPE 1200 Query: 209 QQFQGEVQELAIEE 222 Q E Sbjct: 1201 NTTPATTQPTVNSE 1214
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.1 bits (75), Expect = 6e-04 Identities = 21/87 (24%), Positives = 37/87 (42%), Gaps = 3/87 (3%) Query: 49 EKTEMERQNSALSPKQEETNTTTTATEENPTKDSPSPLETTAQEKENKQENKQEQEKENE 108 + E+ + S +SPKQE++ T E D P+ Q + N + ++ KE Sbjct: 1118 KTQEVPKVTSQVSPKQEQSETVQPQAEPAREND-PTVNIKEPQSQTNTTADTEQPAKETS 1176 Query: 109 SKQNSASPIQNNQKVPTTPTIGKKPLE 135 S N P+ + V T ++ + P Sbjct: 1177 S--NVEQPVTESTTVNTGNSVVENPEN 1201
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 49.5 bits (118), Expect = 2e-10 Identities = 24/84 (28%), Positives = 46/84 (54%), Gaps = 3/84 (3%) Query: 1 MTSALLGLQIVLAVLIVVVVLLQ--KSSSIGLGAYSGSNESLFGARGPASFMAKLTMFLG 58 M ALL + +++A+ +V +++LQ K + +G +G++ +LFG+ G +FM ++T L Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 59 LLFVANTIALGYFYNKEYGKSILD 82 LF ++ LG N + Sbjct: 61 TLFFIISLVLGNI-NSNKTNKGSE 83
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.0 bits (72), Expect = 0.015 Identities = 12/83 (14%), Positives = 30/83 (36%), Gaps = 3/83 (3%) Query: 437 ESTALKSLEDSKQSIADEVALKALEEERKKALE---QAEQGCSVGENETENQEEDKTEAA 493 + +++ + + + E + + E ++ + E E + T Sbjct: 1070 KEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQV 1129 Query: 494 TPKEENQEENKTEAKEESVEVPT 516 +PK+E E + +A+ PT Sbjct: 1130 SPKQEQSETVQPQAEPARENDPT 1152
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 223 bits (570), Expect = 4e-78 Identities = 65/148 (43%), Positives = 94/148 (63%) Query: 4 IGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLKERLEMIQLATKSFK 63 IYPG+FDP+T GH+DII R LF+++ VAV + K PMFS++ERLE I A Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 64 NVECMAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQ 123 N + +FEGL N A++ ++RGLRV+SDFE ELQM NK+L +LET++ + + Sbjct: 62 NAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTE 121 Query: 124 NAFISSSIVRSIIAHKGDASHLVPKEIH 151 +F+SSS+V+ + G+ H VP + Sbjct: 122 YSFLSSSLVKEVARFGGNVEHFVPSHVA 149
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 29.4 bits (66), Expect = 0.031 Identities = 9/23 (39%), Positives = 12/23 (52%) Query: 4 LRYKLLLFVFIGFWGLLVLNLFI 26 KL+LFV + W LL L + Sbjct: 195 TPIKLVLFVALDGWTLLSKGLIL 217
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 33.8 bits (77), Expect = 7e-04 Identities = 31/183 (16%), Positives = 74/183 (40%), Gaps = 10/183 (5%) Query: 106 NVELLKKLSPDLVVTFVGNPKAVEHAKKF--GISFLSFQEKTIAEVMEDID---AQAKAL 160 N+ELL ++ P +V G + E + G F K + A L Sbjct: 88 NLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNL 147 Query: 161 EIDASKKLAKMQETLDFIKERL-KDVKKKKGVELFHKAN--KISGHQALDSDILEKGGID 217 + A LA+ ++ + +K R K + + + G +L +IL++ GI Sbjct: 148 QSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIP 207 Query: 218 N-FGLKYVKFGRADVSVEKIVK-ENPEIIFIWWISPLSPEDVLNNPKFSTIKAIKNKQVY 275 N + + +G VS++++ ++ +++ + + ++ P + + ++ + Sbjct: 208 NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQ 267 Query: 276 KLP 278 ++P Sbjct: 268 RVP 270
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 28.4 bits (63), Expect = 0.014 Identities = 10/38 (26%), Positives = 15/38 (39%) Query: 121 NVNAVVEMADLVEATRAYQANIAAFQSAKNMAQNAIGM 158 VN E +L + Y AN Q+A + I + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 77.0 bits (189), Expect = 6e-22 Identities = 19/77 (24%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Query: 34 EQKGGEFSKLLKQSINELNNTQEQSDKALADMATGQIK-DLHQAAIAIGKAETSMKLMLE 92 Q F+ L +++ +++TQ + G+ L+ + KA SM++ ++ Sbjct: 27 PQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQ 86 Query: 93 VRNKAISAYKELLRTQI 109 VRNK ++AY+E++ Q+ Sbjct: 87 VRNKLVAAYQEVMSMQV 103
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 150 bits (380), Expect = 1e-49 Identities = 40/140 (28%), Positives = 75/140 (53%), Gaps = 1/140 (0%) Query: 5 EILKHLQADAIVLFMKVHNFHWNVKGTDFFNVHKATEEIYEEFADMFDDLAERIVQLGHH 64 L ++ +L+ K+H FHW VKG FF +H+ EE+Y+ A+ D +AER++ +G Sbjct: 15 NSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERLLAIGGQ 74 Query: 65 PLVTLSEALKLTRIKEETKTSFHSKDIFKEILEDYKHLEKEFKELSNTAEKEGDKVTVTY 124 P+ T+ E + I + + + ++ + ++ DYK + E K + AE+ D T Sbjct: 75 PVATVKEYTEHASITDGGNET-SASEMVQALVNDYKQISSESKFVIGLAEENQDNATADL 133 Query: 125 ADDQLAKLQKSIWMLQAHLA 144 + +++K +WML ++L Sbjct: 134 FVGLIEEVEKQVWMLSSYLG 153
>PF06580#Sensor histidine kinase Length = 349 Score = 30.2 bits (68), Expect = 0.014 Identities = 10/71 (14%), Positives = 25/71 (35%), Gaps = 13/71 (18%) Query: 281 IVLQNFLYNAIDAIEALEESEQ-GQVKIEAFIQNEFIVFTIIDNGKEVENKSALFEPFET 339 +++Q + N I + + Q G++ ++ N + + + G + Sbjct: 258 MLVQTLVENGI--KHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK------- 308 Query: 340 TKLKGNGLGLA 350 + G GL Sbjct: 309 ---ESTGTGLQ 316
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 362 bits (930), Expect = e-127 Identities = 119/345 (34%), Positives = 192/345 (55%), Gaps = 26/345 (7%) Query: 19 AEKIGDIASVVGVRDNQLIGYGLVIGLNGTGDK-SGSKFTMQSISNMLESVNVKISADDI 77 +I DIAS+ RDNQLIGYGLV+GL GTGD S FT QS+ ML+++ + Sbjct: 28 TSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMRAMLQNLGITTQGGQS 87 Query: 78 KSKNVAAVMITASLPPFARQGDKIDIQISSIGDAKSIQGGTLVMTPLNAVDGNIYALAQG 137 +KN+AAVM+TA+LPPFA G ++D+ +SS+GDA S++GG L+MT L+ DG IYA+AQG Sbjct: 88 NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIMTSLSGADGQIYAVAQG 147 Query: 138 AITSGN-----------SNNLLSAHIINGATIEREVSYDLFHKNAMVLSLKNPNFKNAIQ 186 A+ SA + NGA IERE+ +VL L+NP+F A++ Sbjct: 148 ALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSVNLVLQLRNPDFSTAVR 207 Query: 187 VQNTLNKV----FGNKVAIALDPKTIQITRPERFSMVEFLALVQEIPINYSAKNKIIVDE 242 V + +N +G+ +A D + I + +P + +A ++ + + K++++E Sbjct: 208 VADVVNAFARARYGDPIAEPRDSQEIAVQKPRVADLTRLMAEIENLTVETDTPAKVVINE 267 Query: 243 KSGTIVSGVDIMVHPIVVTSQDITLKITKEPLDNL--------KNVQDLDNNMSLDTAHN 294 ++GTIV G D+ + + V+ +T+++T+ P VQ + M++ Sbjct: 268 RTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFSRGQTAVQPQTDIMAMQEGSK 327 Query: 295 TLSSNGKNITIAGVVKALQKIGVSAKGMVSILQALKKSGAISAEM 339 G ++ +V L IG+ A G+++ILQ +K +GA+ AE+ Sbjct: 328 VAIVEGPDLR--TLVAGLNSIGLKADGIIAILQGIKSAGALQAEL 370
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.3 bits (71), Expect = 0.009 Identities = 16/50 (32%), Positives = 21/50 (42%), Gaps = 7/50 (14%) Query: 30 VAIVGESGSGKSSIANIIMRLNPR----FKPHNGEVLFETTNLLKESEEF 75 + I GESG+GK +A + R F N + L ESE F Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRD---LIESELF 209
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 551 bits (1420), Expect = 0.0 Identities = 179/582 (30%), Positives = 294/582 (50%), Gaps = 66/582 (11%) Query: 11 VDFFIKLNKKQKIALIAAGVLITALLVFLLLYPFKEKDYAQGGYGVLFERLDSSDNALIL 70 +++ +L +I LI AG A++V ++L+ K DY LF L D I+ Sbjct: 13 LEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWA-KTPDYR-----TLFSNLSDQDGGAIV 66 Query: 71 QHLQQNQIPYKILKDD-TILIPKDKVYEERITLASQGIPKTSKVGFEIFDTKDFGATDFD 129 L Q IPY+ I +P DKV+E R+ LA QG+PK VGFE+ D + FG + F Sbjct: 67 AQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFS 126 Query: 130 QNIKLIRAIEGELSRTIESLNPILKANVHIAIPKDSVFVAKEVPPSASVMLKLKPDMKLS 189 + + RA+EGEL+RTIE+L P+ A VH+A+PK S+FV ++ PSASV + L+P L Sbjct: 127 EQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALD 186 Query: 190 PTQILGIKNLIAAAVPKLTTENVKIVNENGESIGEGDILENSKELALEQLRYKQNFENIL 249 QI + +L+++AV L NV +V+++G + + + + ++L QL++ + E+ + Sbjct: 187 EGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNT--SGRDLNDAQLKFANDVESRI 244 Query: 250 ENKIVNILAPIVGGKNKVVARVNAEFDFSQKKSTKETFDPNN-----VVRSEQNLEEKKE 304 + +I IL+PIVG N V A+V A+ DF+ K+ T+E + PN +RS Q ++ Sbjct: 245 QRRIEAILSPIVGNGN-VHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQV 303 Query: 305 GAPKKQVGGVPGVVSN-IGPVQGLKDNKEPEKYEKSQN---------------------- 341 GA GGVPG +SN P P + +QN Sbjct: 304 GAGYP--GGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNE 361 Query: 342 TTNYEVGKTISEIKGEFGTLVRLNAAVVVDGKYKIALKDGANTLEYEPLSDESLKKINAL 401 T+NYEV +TI K G + RL+ AVVV+ K L DG + PL+ + +K+I L Sbjct: 362 TSNYEVDRTIRHTKMNVGDIERLSVAVVVNYK---TLADG----KPLPLTADQMKQIEDL 414 Query: 402 VKQAIGYNQNRGDDVAVSNFEFNPMAPMLDNATLSEKIMHKTQKVLGSFTPLIKYILVFI 461 ++A+G++ RGD + V N F+ + T E + Q + +++LV + Sbjct: 415 TREAMGFSDKRGDTLNVVNSPFSAVDN-----TGGELPFWQQQSFIDQLLAAGRWLLVLV 469 Query: 462 VLFIFYKKVIVPFSERMLEVVPDEDKEVKSMFEEMDEEEDELNKLGDLRKKVEDQLGLNA 521 V +I ++K + P R +E ++ + E + E L+K L+++ +Q Sbjct: 470 VAWILWRKAVRPQLTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQ----- 524 Query: 522 TFSEEEVRYEIVLEKIRGTLKERPDEIAMLFKLLIKDEISSD 563 + E++ ++IR E D + L+I+ +S+D Sbjct: 525 -----RLGAEVMSQRIR----EMSDNDPRVVALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 349 bits (898), Expect = e-122 Identities = 121/338 (35%), Positives = 208/338 (61%), Gaps = 4/338 (1%) Query: 8 KQKAQLDELSMSEKIAILLIQVGEDTTGEILRHLDIDSITEISKQIVQLNGTDKQIGAAV 67 K+ + L+ +K AILL+ +G + + ++ ++L + I ++ +I +L ++ V Sbjct: 7 KEILDVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNV 66 Query: 68 LEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEARKVMDKLTKSLQTQKNFAYLGKIKP 127 L EF + + ++I GG++YARELL ++LG+++A +++ L +LQ+ + F ++ + P Sbjct: 67 LLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQS-RPFEFVRRADP 125 Query: 128 QQLADFIINEHPQTIALILAHMEAPNAAETLSYFPDEMKAEISIRMANLGEISPQVVKRV 187 + +FI EHPQTIALIL++++ A+ LS P E++ ++ R+A + SP+VV+ V Sbjct: 126 ANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREV 185 Query: 188 STVLENKLESLTSYK-IEVGGLRAVAEIFNRLGQKSAKTTLARIESVDNKLAGAIKEMMF 246 VLE KL SL+S GG+ V EI N +K+ K + +E D +LA IK+ MF Sbjct: 186 ERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMF 245 Query: 247 TFEDISKLDNFAIREILKVADKKDLSLALKTSTQDLTDKFLNNMSSRAAEQFVEEMQYLG 306 FEDI LD+ +I+ +L+ D ++L+ ALK+ + +K NMS RAA E+M++LG Sbjct: 246 VFEDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLG 305 Query: 307 AVKIKDVDVAQRKIIEIVQSLQEKG--VIQTGEEEDVI 342 + KDV+ +Q+KI+ +++ L+E+G VI G EEDV+ Sbjct: 306 PTRRKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343 Score = 31.3 bits (71), Expect = 0.006 Identities = 20/103 (19%), Positives = 41/103 (39%), Gaps = 3/103 (2%) Query: 4 KLTPKQKAQLDELSMSEKIAILLIQVGEDTTGEILRHLDIDSITEISKQIVQLNGTDKQI 63 + P + + IA++L + IL L + T ++++I ++ T ++ Sbjct: 122 RADPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEV 181 Query: 64 GAA---VLEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEAR 103 VLE+ A S Y + GG++ E++ E Sbjct: 182 VREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKF 224
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 37.1 bits (85), Expect = 4e-05 Identities = 46/212 (21%), Positives = 95/212 (44%), Gaps = 17/212 (8%) Query: 45 PNPEEPLEKKAIENDLIDCLLKKTDELSSHLVKLQMQFEKAQEES-KALIENAKNDGYKI 103 P E + E +I+ + L L +LQMQ A E+ +A I + G+K Sbjct: 17 PPQAEFVPIVEPEETIIE---EAEPSLEQQLAQLQMQ---AHEQGYQAGIAEGRQQGHKQ 70 Query: 104 GFKEGEEKMRNELTHSVNEEKNQLLHAITALDEKMKKSEDHLMALE----KELSAIAIDI 159 G++EG + L + E K+Q + + + + + L AL+ L +A++ Sbjct: 71 GYQEG---LAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEA 127 Query: 160 AKEVILKEVEDNSQKVALALAEELLKNVLDATDIHLKVNPLDYPYLNERLQNASKI---K 216 A++VI + ++ + + + L + L + L+V+P D +++ L + + Sbjct: 128 ARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWR 187 Query: 217 LESNEAISKGGVMITSSNGSLDGNLMERFKTL 248 L + + GG +++ G LD ++ R++ L Sbjct: 188 LRGDPTLHPGGCKVSADEGDLDASVATRWQEL 219
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 139 bits (353), Expect = 3e-37 Identities = 99/437 (22%), Positives = 174/437 (39%), Gaps = 85/437 (19%) Query: 9 NIRNFSIIAHIDHGKSTLADCLIAECNAIS---NREMTSQVMDTMDIEKERGITIKAQSV 65 I N ++AH+D GK+TL + L+ AI+ + + + D +E++RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 66 RLNYTLKGEDYVLNLIDTPGHVDFSYEVSRSLCSCEGALLVVDATQGVEAQTIANTYIAL 125 + E+ +N+IDTPGH+DF EV RSL +GA+L++ A GV+AQT + Sbjct: 62 SFQW----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 126 DNHLEILPVINKIDLPNANVLEVKQDIEDTIGIDCSNANEVSAKARLGIKD--------- 176 + + INKID ++ V QDI++ + + +V + + + Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDT 177 Query: 177 -------LLEKIITTIPAPSGDFNAPLKALIYD-------------------------SW 204 LLEK ++ + + ++ + Sbjct: 178 VIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNK 237 Query: 205 F--------------------DNYLGALALVRIMDGSINTEQEILVMGTGKKHGVLGLYY 244 F LA +R+ G ++ + + K + +Y Sbjct: 238 FYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-KITEMYT 296 Query: 245 PNPLKKIPTKSLECGEIGIV---SLGLKSVTDIAVGDTLTDAKNPTPKPIEGFMPAKPFV 301 + GEI I+ L L SV +GDT P + IE P + Sbjct: 297 SINGELCKIDKAYSGEIVILQNEFLKLNSV----LGDTKLL---PQRERIEN---PLPLL 346 Query: 302 FAGLYPIETDRFEDLREALLKLQLNDCALNFEPESSVALGFGFRVGFLGLLHMEVIKERL 361 + P + + E L +ALL++ +D L + +S+ + FLG + MEV L Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATH---EIILSFLGKVQMEVTCALL 403 Query: 362 EREFGLNLIATAPTVVY 378 + ++ + + PTV+Y Sbjct: 404 QEKYHVEIEIKEPTVIY 420 Score = 31.0 bits (70), Expect = 0.015 Identities = 15/75 (20%), Positives = 28/75 (37%), Gaps = 2/75 (2%) Query: 405 IKEPFVRATIITPSEFLGNLMQLLNNKRGIQEKMEYLNQSRVMLTYSLPSNEIVMDFYDK 464 + EP++ I P E+L + L + V+L+ +P+ I ++ Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCI-QEYRSD 592 Query: 465 LKSCTKGYASFDYEP 479 L T G + E Sbjct: 593 LTFFTNGRSVCLTEL 607
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 30.3 bits (68), Expect = 0.008 Identities = 9/40 (22%), Positives = 16/40 (40%) Query: 3 NGYYAATGAMATQFNRLDLTSNNLANLNTNGFKRDDAITG 42 + A + L+ SNN+++ N G+ R I Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMA 41
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.1 bits (91), Expect = 3e-05 Identities = 42/182 (23%), Positives = 71/182 (39%), Gaps = 33/182 (18%) Query: 37 APYFAKEFTHTNDPTLALISAFLVFMLGFFMRPLGSLFFGKLGDKKGRKTSMVYSIILMA 96 P A +F T + +AF++ G+ +GKL D+ G K +++ II+ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSI------GTAVYGKLSDQLGIKRLLLFGIIINC 90 Query: 97 LGSFLLALLPTKEIVGEWAFLFLLLARLLQGFSVGGE------YGVVATYLSELGKNGKK 150 GS + VG F L++AR +QG G VVA Y+ + + Sbjct: 91 FGSVIGF-------VGHSFFSLLIMARFIQG--AGAAAFPALVMVVVARYIPKENRGKAF 141 Query: 151 GFYGSFQYVTLVGGQLLAIFSLFIVENIYTHEQISAFAWRYLFALGGILALLSLFLRNIM 210 G GS + +G + I I+ W YL + I + FL ++ Sbjct: 142 GLIGS---IVAMGEGVGPAIGGMIAHYIH---------WSYLLLIPMITIITVPFLMKLL 189 Query: 211 EE 212 ++ Sbjct: 190 KK 191
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.035 Identities = 23/123 (18%), Positives = 43/123 (34%), Gaps = 12/123 (9%) Query: 258 SNPTNPTLKEPKQETKEREPTLTKETLTPTTPKPATLKPIMPTPIMPASAPNLENDNKTE 317 S T + KQE+K E K T + + + N++ + +T Sbjct: 1034 SETTETVAENSKQESKTVE----KNEQDATETTAQNRE------VAKEAKSNVKANTQTN 1083 Query: 318 NHNTPNHPKKEESPQENAQEEMIEETIKENLKEEEKETQNAPSFSPLTPTSAKKPVMVKE 377 KE E + +E+ +E K E ++TQ P + ++ V+ Sbjct: 1084 EVAQSGSETKETQTTETKETATVEK--EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQP 1141 Query: 378 LSE 380 +E Sbjct: 1142 QAE 1144
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 31.6 bits (71), Expect = 0.001 Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 5/62 (8%) Query: 186 DFINDTQQNPKEPSEPCKIAPQKVSFNQVVFKKIKRKLNHFIGNILARTEVYKKLVAKYD 245 D I+DTQ + +E + V+ N V+ K ++ +G +V KLVA Y Sbjct: 42 DRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMG-----IQVRNKLVAAYQ 96 Query: 246 DL 247 ++ Sbjct: 97 EV 98
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 27.8 bits (61), Expect = 0.025 Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 5/52 (9%) Query: 60 GELVPLGIVVETILSAIKSSDKGIILIDGYPRSVEQMQALDKELSAQNEVVL 111 G+L+ I VE LS I + D L+ P++ E++ ALDKEL A+ + L Sbjct: 127 GKLIAYPIAVEA-LSLIYNKD----LLPNPPKTWEEIPALDKELKAKGKSAL 173
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.2 bits (133), Expect = 1e-10 Identities = 24/110 (21%), Positives = 44/110 (40%), Gaps = 6/110 (5%) Query: 194 ILIAEDSLSALKTLEKIVQTLELRYLAFPNGKELLDYLYEKEHYQQVGVVITDLEMPVIS 253 IL+A+D + L + + N L ++ +V+TD+ MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA----GDGDLVVTDVVMPDEN 61 Query: 254 GFEVLKTIKADSRTEHLPVIINSSMSSDSNRQLAQSLEADGFVVKSNILE 303 F++L IK LPV++ S+ ++ A A ++ K L Sbjct: 62 AFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 28.5 bits (63), Expect = 0.005 Identities = 13/27 (48%), Positives = 17/27 (62%) Query: 16 KRKKLLTELAELEAEIKVSSERKSSFN 42 R KL ELAEL AE+K+ S ++ N Sbjct: 149 ARSKLREELAELTAELKIYSVIQAEIN 175
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 899 bits (2325), Expect = 0.0 Identities = 284/1038 (27%), Positives = 516/1038 (49%), Gaps = 40/1038 (3%) Query: 1 MYKTAINRPITTLMFALAIVFFGTMGFKKLSVALFPKIDLPTVVVTTTYPGASAEIIESK 60 M I RPI + A+ ++ G + +L VA +P I P V V+ YPGA A+ ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTDKIEEAVMGIDGIKKVTSTSSKNVSIVV-IEFELEKPNEEALNDVVNKISSVR-FDDS 118 VT IE+ + GID + ++STS S+ + + F+ + A V NK+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 119 NIKKPSINKFDTDSQAIISLFVSSSSVPAT--TLNDYTKNTIKPMLQKIDGVGGVQLNGF 176 +++ I+ + S ++ S + T ++DY + +K L +++GVG VQL G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 177 RERQIRIYADPTLMNKYNLTYADLFSTLKAENVEIDGGRIVNS------QRELSILINAN 230 + +RI+ D L+NKY LT D+ + LK +N +I G++ + Q SI+ Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 231 SYSVADVEKIQV-----GNHVRLGDIAKIEIGLEEDNTFASFKDKPGVILEIQKIAGANE 285 + + K+ + G+ VRL D+A++E+G E N A KP L I+ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 286 IEIVDRVYEALKHIQAISP-NYEIRPFLDTTGYIRTSIEDVKFDLVLGAVLAVLVVFAFL 344 ++ + L +Q P ++ DTT +++ SI +V L +L LV++ FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 345 RNGTITLVSAISIPISVMGTFALIQWMGFSLNMLTMVALTLAIGIIIDDAIVVIENIHK- 403 +N TL+ I++P+ ++GTFA++ G+S+N LTM + LAIG+++DDAIVV+EN+ + Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 404 KLEMGMNKRKASYEGVREIGFALVAISAMLLSVFVPIGNMKGIIGRFFQSFGITVALAIA 463 +E + ++A+ + + +I ALV I+ +L +VF+P+ G G ++ F IT+ A+A Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 464 LSYVVVVTIIPMVSSVVVNPRHS-------RFYVWSEPFFKALESRYTKLLQWVLNHKLI 516 LS +V + + P + + ++ P + F+ W F + YT + +L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 517 IFIAVVLVFVGSLFVASKLGMEFMLKEDRGRFLVWLKAKPGVSIDY----MTQKSKIFQK 572 + L+ G + + +L F+ +ED+G FL ++ G + + + Q + + K Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 573 AIEKHAEVEFTTLQVGY-GTTQNPFKAKIFVQLKPLKERKKEHELGQFELMSALRKELKS 631 + + E FT + G QN FV LKP +ER E ++ + EL Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNA--GMAFVSLKPWEERNG-DENSAEAVIHRAKMELGK 656 Query: 632 MPEAKGLENINLSEVSLIGGGGDSSPFQTFVFSHSQEAVDKSVANLKKFLLESPELKGKI 691 + + + N+ + G ++ F + + D + L + + + Sbjct: 657 IRDGF-VIPFNMPAIV---ELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASL 712 Query: 692 EGYHTSTSESQPQLQLKILRQNANKYGVSAQTIGSVVSSAFSGTSQASVFKEDGKEYDMI 751 + E Q +L++ ++ A GVS I +S+A G + + F + G+ + Sbjct: 713 VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGG-TYVNDFIDRGRVKKLY 771 Query: 752 IRVPDNKRISVEDIKRLQVRNKYDKLMFLDALVEITETKSPSSISRYNRQRSVTVLAQPK 811 ++ R+ ED+ +L VR+ +++ A + RYN S+ + + Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAA 831 Query: 812 AGISLGEILTQVSKNTKEWLVEGANYRFTGEADNAKETNGEFLIALATAFVLIYMILAAL 871 G S G+ + + +N L G Y +TG + + + + +A +FV++++ LAAL Sbjct: 832 PGTSSGDAMALM-ENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAAL 890 Query: 872 YESILEPFIIMVTMPLSFSGAFFALGLVHQPLSMFSMIGLILLIGMVGKNATLLIDVANE 931 YES P +M+ +PL G A L +Q ++ M+GL+ IG+ KNA L+++ A + Sbjct: 891 YESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKD 950 Query: 932 -ERKKGLNIQEAILFAGKTRLRPILMTTIAMVCGMLPLALASGDGAAMKSPIGIAMSGGL 990 K+G + EA L A + RLRPILMT++A + G+LPLA+++G G+ ++ +GI + GG+ Sbjct: 951 LMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGM 1010 Query: 991 MISMVLSLLIVPVFYRLL 1008 + + +L++ VPVF+ ++ Sbjct: 1011 VSATLLAIFFVPVFFVVI 1028
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.0 bits (122), Expect = 1e-09 Identities = 22/69 (31%), Positives = 34/69 (49%) Query: 40 STGIVDSIKVTEGSVVKKGDVLLLLYNQDKQAQSDSTEQQLIFAKKQYQRYSKIGGAVDK 99 IV I V EG V+KGDVLL L +A + T+ L+ A+ + RY + +++ Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 100 NTLESYEFN 108 N L + Sbjct: 163 NKLPELKLP 171 Score = 31.7 bits (72), Expect = 0.003 Identities = 21/152 (13%), Positives = 48/152 (31%), Gaps = 25/152 (16%) Query: 70 QAQSDSTEQQLIFAKKQYQR--YSKIGGAVDKNTLESYEFNYRRLESDYAYSIALLNKTI 127 +++ S +++ + ++ K+ D + + E ++ Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDN--IGLLTLELAKNEER-------QQASV 329 Query: 128 LRAPFDGVIASKNIQVGEGVSANNTVLLRLVSHARKLVIE--FDSKYINAVKVG------ 179 +RAP + + GV L+ +V L + +K I + VG Sbjct: 330 IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIK 389 Query: 180 -DTYTYSIDGDSNQHEAKITKIYP--TVDENT 208 + + Y+ G K+ I D+ Sbjct: 390 VEAFPYTRYGYL---VGKVKNINLDAIEDQRL 418
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.042 Identities = 16/113 (14%), Positives = 40/113 (35%), Gaps = 16/113 (14%) Query: 208 LARMIALQKKLEQIKTDIKRVTKLYDKGLTTIDDL-----QSLKAQGNLSEY--DILDMQ 260 LAR+ + K+ + + L K + + ++A L Y + ++ Sbjct: 220 LARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIE 279 Query: 261 FALEQNRLTLEYLTNLSVKNLKKTTIDAPNLQLRERQD-LVSLREQISALRYQ 312 + + + +T K +D +LR+ D + L +++ + Sbjct: 280 SEILSAKEEYQLVTQ----LFKNEILD----KLRQTTDNIGLLTLELAKNEER 324
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.003 Identities = 13/95 (13%), Positives = 25/95 (26%), Gaps = 20/95 (21%) Query: 60 ILENDDETNLKKIAYAEFSKFAECVRPSGFYNQKAKRLISLSENILKDFQSFENFKQEAT 119 L + +A+ E + VR + +KA E+ Sbjct: 458 ALRSAPALA-GCVAFDELREQPVAVRAFPW--RKAPGP-------------LEDADVLRL 501 Query: 120 REWLLDQKGIGKESADAILCYVCAKEVMVVDKYSY 154 +++ G G+ SA + D Sbjct: 502 ADYVETTYGTGEASAQTTEQAINV----AADMNRV 532
>FLAGELLIN#Flagellin signature. Length = 507 Score = 245 bits (626), Expect = 3e-77 Identities = 127/518 (24%), Positives = 209/518 (40%), Gaps = 22/518 (4%) Query: 2 AFQVNTNINAMNAHVQSALTQNALKTSLERLSSGLRINKAADDASGMTVADSLRSQASSL 61 A +NTN ++ +Q++L +++ERLSSGLRIN A DDA+G +A+ S L Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 GQAIANTNDGMGIIQVADKAMDEQLKILDTVKVKATQAAQDGQTTESRKAIQSDIVRLIQ 121 QA N NDG+ I Q + A++E L V+ + QA + K+IQ +I + ++ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 GLDNIGNTTTYNGQALLSGQFTNKEFQVGAYSNQSIKASIGSTTSDKIGQVRI-ATGALI 180 +D + N T +NG +LS + QVGA ++I + +G G Sbjct: 121 EIDRVSNQTQFNGVKVLSQDN-QMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 181 TASGDISLTFKQVDGVNDVTLEGVKISSSAGTGIGVLAEVINKNSNQTGVRAHASVITTS 240 GD+ +FK V G + + K +G V ++ V A +TT Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 241 DVAVQSGSLSNLTLNGIHLGNIVDIKKNDSDGRLVAAINAVTSETGVEAYTDQNGRLNLR 300 D N + K A A+ + + + + Sbjct: 240 DAE-----------NNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTID 288 Query: 301 SLDGRGIEIKTDSTSNGPSALTMVNGGQDLTKGSTNYGRLSLTRLDAKSINV------VS 354 + G K +T NG V S + +N + Sbjct: 289 TKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKT 348 Query: 355 ASDSQHLGFSAIGFGESQVAETTVNLRDVTGNFNANVKSASGANYNAVIASGNQSL---G 411 ++S L ++ TVN + T N + + +G + S Sbjct: 349 KNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINE 408 Query: 412 SGVTTLRGAMVVIDVAESAMKMLDKVRSDLGSVQNQMISTVNNISITQVNVKAAESQIRD 471 + + +SA+ +D VRS LG++QN+ S + N+ T N+ +A S+I D Sbjct: 409 DAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIED 468 Query: 472 VDFAEESANFNKNNILAQSGSYAMSQANTVQQNILRLL 509 D+A E +N +K IL Q+G+ ++QAN V QN+L LL Sbjct: 469 ADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 27.8 bits (61), Expect = 0.032 Identities = 27/112 (24%), Positives = 54/112 (48%), Gaps = 11/112 (9%) Query: 23 NQTTELHHKNPYELLVATILSAQCTDARVNKITPKLFEKYPSVKDLAL-----ASLEEIK 77 N+ E+ K E A ++ + T +I + K P+ K+L L A +E++K Sbjct: 132 NKVVEMSKKAVQETQKAVSVAGEATFLIEKQI---MLNKSPNNKELELTKEEFAKVEQVK 188 Query: 78 EIIKSVSYFNNKSKHLISMAQKVVRDFKGVIPSTQKELMSLDGVGQKTANVV 129 E + + +++ + AQKV+ G+ PS + ++++ V + +NVV Sbjct: 189 ETLMASERALDET---VQEAQKVLNMVNGLNPSNKDQVLAKKDVAKAISNVV 237
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 99 bits (249), Expect = 2e-30 Identities = 25/77 (32%), Positives = 47/77 (61%) Query: 34 LICDYKNLLDMEIVFSAELGSTQIPLLQILRFEKGSVIDLQKPAGESVDTFVNGRVIGKG 93 + D ++D+ + + ELG T++ + ++LR +GSV+ L AGE +D +NG +I +G Sbjct: 50 AMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQG 109 Query: 94 EVMVFERNLAIRLNEIL 110 EV+V +R+ +I+ Sbjct: 110 EVVVVADKYGVRITDII 126
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 46.9 bits (111), Expect = 3e-08 Identities = 30/206 (14%), Positives = 66/206 (32%), Gaps = 11/206 (5%) Query: 101 PTPPTPPKPIEKPKPKPKPEPKKPNHKHKALKKVEKVEEKKVVEEKKEEKVVEQKVEQKK 160 P P +PI P + VE E + + E +E V + + K Sbjct: 41 IELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPK 100 Query: 161 IEEKKPVKKEFDPNQLSFLPKEVAPPRQENNKGLDNQTRRDIDELYGEEFGDLGTAEKDF 220 + K K+ + + ++V P +N Sbjct: 101 PKPKPKPVKKVEQPK-----RDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVA- 154 Query: 221 IRNNLRDIGRITQKYLEYPQVAAYLGQDGMNAVEFYLHPNGDISDLKIIIGSEYKMLDDN 280 +++ +YP A L +G V+F + P+G + +++I+ M + Sbjct: 155 -----SGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFERE 209 Query: 281 TLKTIQIAYKDYPRPKTKTLIRIRVR 306 ++ + +P + ++ I + Sbjct: 210 VKNAMRRWRYEPGKPGSGIVVNILFK 235
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 29.7 bits (67), Expect = 0.006 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 87 LQSYSVMLFFNLLLLIDVLGFLPFSIYHHFMASLIFSALFCSSLFLSSPLLGVIALVALS 146 L Y F L+L+ +LPFS S + + +L PLL V AL+A++ Sbjct: 45 LSDYYFEHFSKLMLIPAEQSYLPFSQ----ALSYVVDNVLLEFFYLCFPLLTVAALMAIA 100 Query: 147 SSLL 150 S ++ Sbjct: 101 SHVV 104
>PF03944#delta endotoxin Length = 633 Score = 32.3 bits (73), Expect = 0.002 Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Query: 68 LHHQEKLLNQCMLSQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILAVSKIDTA 127 L E+ LNQ + + + A +AEL A+V + + + FL+ + L+++ Sbjct: 94 LRETERFLNQRLNTDTV-ARVNAELTGLQANVEEFNRQVDNFLNPNRNAVPLSITSSVNT 152 Query: 128 THKQVLQKLQEYQQYASQFLALVPLSAKKSQNLN 161 + L +L ++Q Q L L+PL A+ + NL+ Sbjct: 153 MQQLFLNRLPQFQMQGYQLL-LLPLFAQAA-NLH 184
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.045 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 3/36 (8%) Query: 51 TPKNILMIGSTGVGKTEIARRI---AKIMKLPFVKV 83 T +++ G +G GK +AR + K PFV + Sbjct: 159 TDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>PF07520#Virulence protein SrfB Length = 1041 Score = 29.2 bits (65), Expect = 0.010 Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 4/49 (8%) Query: 121 LEAEDNKIAAIGSGG---NFALSAARALDNFAHLEPRKLVEESLKIAGD 166 E+ ++A I GG + ++ R DN L P + E ++AGD Sbjct: 590 GESPSLRLACIDVGGGTTDLMVTTYRGEDNRV-LHPEQTFREGFRVAGD 637
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 92.6 bits (230), Expect = 1e-22 Identities = 81/407 (19%), Positives = 154/407 (37%), Gaps = 40/407 (9%) Query: 3 KKIFPLALVSSLRFLGLFIVLPVISLYADSFHSSSPLL--VGLAVGGAYLTQIIFQTPMG 60 + + + +L +G+ +++PV+ S+ + G+ + L Q +G Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 61 ILSDKIGRKVVVMVCLLLFLAGSLVCFIANDIVWLVIGRFIQGM-GALGGVVSAMVADEV 119 LSD+ GR+ V++V L + A + L IGR + G+ GA G V A +AD Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADIT 124 Query: 120 KEEERTKAMAIMGAFIFISFTISMAIGPGVVAFFGG--AKWLFLLTAILTLLSLLM-LLK 176 +ER + M A F M GP + GG F A L L+ L Sbjct: 125 DGDERARHFGFMSA----CFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFL 180 Query: 177 VKDAPKISYQIKNIKAYQPNSKALYLLYLSSFFEKAFMTLIFVL-----IPLAL-----V 226 + ++ K + +A P + + ++ A M + F++ +P AL Sbjct: 181 LPESHKGERRPLRREALNPLASFRWARGMTVV--AALMAVFFIMQLVGQVPAALWVIFGE 238 Query: 227 NEFYKDESFLILVYVPGALLGVLSMGVASVMAEKYNKPKGVMLSGVLLFIVSYWCLFLAD 286 + F+ D + + + +L L+ + + + ++ G++ Y L A Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 287 SSFLGKYLWLFILGVAFFFIGFATLEPIMQSLASKFARVHEKGKVLGQFTTFGYLGSFVG 346 W+ + P +Q++ S+ +G++ G L S VG Sbjct: 299 RG------WMAFPIM-VLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVG 351 Query: 347 GVSGGLSY-HHLGVSNTSLIVVALGLIW--GLSLFLLNNPSKQKNVY 390 + Y + N G W G +L+LL P+ ++ ++ Sbjct: 352 PLLFTAIYAASITTWN--------GWAWIAGAALYLLCLPALRRGLW 390
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 49.4 bits (118), Expect = 1e-08 Identities = 52/290 (17%), Positives = 103/290 (35%), Gaps = 18/290 (6%) Query: 35 ALLSDIAKSFEMESATVGLMITLYAWLVSLGSLPLMLFSAKIERKRLLLFLFALFILSHI 94 LL D+ S +A G+++ LYA + + L S + R+ +LL A + + Sbjct: 30 GLLRDLVHS-NDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYA 88 Query: 95 LSALAWNFWVLLISRIGIAFAHSIFWSITASLVIRVAPRNKKQQALGLLALGSSLAMILG 154 + A A WVL I RI +A ++ + + + +++ + G ++ M+ G Sbjct: 89 IMATAPFLWVLYIGRI-VAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG 147 Query: 155 LPLGRIIGQMLDWRSTFGVIGGVATLIALLMYKLLPP----------LPSKNAGTLSSLP 204 LG ++G + F + L L LLP + N Sbjct: 148 PVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWA 206 Query: 205 VLVKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQISQFSPDITTLMLFVFGLAG-VVGS 263 + + ++ ++ I F + + L FG+ + + Sbjct: 207 RGMTVVAALMAVFFIMQLVGQVPAALWVI--FGEDRFHWDATTIGISLAAFGILHSLAQA 264 Query: 264 FLFGRLYAK-NSRKFIAFAMVLVICPQLLLFVFKNSEWVVFLQIFLWGIG 312 + G + A+ R+ + M+ +L F W+ F + L G Sbjct: 265 MITGPVAARLGERRALMLGMIADGT-GYILLAFATRGWMAFPIMVLLASG 313
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.2 bits (70), Expect = 0.010 Identities = 29/178 (16%), Positives = 56/178 (31%), Gaps = 5/178 (2%) Query: 132 EANKSGIELEQERQKTEQERQKTNKSEIELEQERQKTNKSGIELANSQIKAEQERQKTEQ 191 E K ++ T Q S +E + +++ + +E E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 192 EKQKANKSEIELEQQKQKTINTQRDLIKEQKDFIKETEQNCQEKHGQLFIKKARIKTGIT 251 KQ++ E + + T + + + + T+ N + G + +T T Sbjct: 1044 SKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKET 1103 Query: 252 TGIAIE----IEAECKTPKPTKTNQT-PIQPKHLPNSKQPRSQRGSKAQELIAYLQKE 304 + E +E E P T+Q P Q + Q R + I Q + Sbjct: 1104 ATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQ 1161
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 30.4 bits (68), Expect = 0.011 Identities = 20/110 (18%), Positives = 40/110 (36%), Gaps = 15/110 (13%) Query: 45 KIKAFHKDYEILETTH-EVFEKERIDIAFFSAGGSVSEEFATSAAKTALVIDNTSFFRLN 103 K+ A ++ Y+ + +H + + I + G +S+ A S ID S Sbjct: 131 KVYATYRKYQAIRISHGNISDDGSI---YKLTGIWLSKTSADSLGN----IDQGSLIETG 183 Query: 104 KKVPLVVPEINAKEIFNAPLNIIANPNCSTIQMTQIL--NPLHLHFKIKS 151 ++ L VP + ++ + +T L NP + +S Sbjct: 184 ERCVLTVPSTDIEKEILDL-----AAATERLNLTDALNSNPAGNLYDWRS 228
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 804 bits (2077), Expect = 0.0 Identities = 220/1057 (20%), Positives = 450/1057 (42%), Gaps = 63/1057 (5%) Query: 5 IIDLSVKNKLLTTLITLLIFLASLWAIKSVRLDALPDLSPAQVVVQITYPNQSPKIVQEQ 64 + + ++ + ++ +++ +A AI + + P ++P V V YP + VQ+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 VTYPLVSTFMSIANIDTVRGIS-SYESGLVYIIFKDGVNLYWARDRVLEQLNRVGN-LPK 122 VT + I N+ + S S S + + F+ G + A+ +V +L LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 123 DAKV-EIGSDSTSIGWAYQYALSSDSKNLS--DLKVLQDFYYRYALLGVDGVSEVASVGG 179 + + I + +S + SD+ + D+ + L ++GV +V G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 FVKDYEITLQNDSLIRYNLSLEQVANAIKNSNNDTGGGVI------LENGFEKIIRSHGY 233 I L D L +Y L+ V N +K N+ G + I + Sbjct: 181 -QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 IQSLKDLEEIVVK-KEGAIPLKIKDIASVRLAPKPRRGAANLNGDKEVVGGIVMVRYHAD 292 ++ ++ ++ ++ +++KD+A V L + A +NG K G + + A+ Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARING-KPAAGLGIKLATGAN 298 Query: 293 TYKVLKTIKEKIATLQASNP-DVKITSVYDRSELIEKGIDNLIHTLIEESVIVLVIIAIF 351 K IK K+A LQ P +K+ YD + ++ I ++ TL E ++V +++ +F Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 352 LLHFRSALVVIITLPLSVCISFLLMRYFNIEASIMSLGGIAIAIGAMVDAAIVMVENAHK 411 L + R+ L+ I +P+ + +F ++ F + +++ G+ +AIG +VD AIV+VEN + Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 412 HLQHIDTKDNTQRINGIMQGVKHVGGAIFFALMIIVVSFLPIFALTGQEEKLFAPLAYTK 471 + +D + + + GA+ M++ F+P+ G ++ + T Sbjct: 419 VMM----EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 472 TFAMLVGALLSITMVPILMVWLIKGRILEESKNPINAFF----------MKIYGVSLKVV 521 AM + L+++ + P L L+K E +N FF + Y S+ + Sbjct: 475 VSAMALSVLVALILTPALCATLLKPVSAEHHENK-GGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 522 LKFRYAFLIASVLGLGSLYLMYKKLNWEFIPQINEGVIMYMPVTLNGVGIDTALEYLKKS 581 L +L+ L + + +++ +L F+P+ ++GV + M G + + L + Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 582 NSTIKRLDF--VKQVFGKVGRANTSTDAAGLGMIETYIELKPQNEWKEKLSYKEVRDKL- 638 + + V+ VF G + S A GM ++ LKP W+E+ + + + Sbjct: 594 TDYYLKNEKANVESVFTVNGFS-FSGQAQNAGM--AFVSLKP---WEERNGDENSAEAVI 647 Query: 639 -EKTLQLKGLTNSWTYPIRGRTDMLLTGIRTPLGIKL-------YGNDTDKLQELAILME 690 ++L + + + P + L G T +L + T +L + Sbjct: 648 HRAKMELGKIRDGFVIPFNMPAIVEL-GTATGFDFELIDQAGLGHDALTQARNQLLGMAA 706 Query: 691 QQLKTLKESLSVFAERSNNGYYITLDLNDENLARYGINKNAVLDTIKFALGGATLTTMIK 750 Q +L +SV + L+++ E G++ + + TI ALGG + I Sbjct: 707 QHPASL---VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFID 763 Query: 751 GVESYPISLRLEGTERNTIEKLQNLYIKTAYNYM-PLRELAHVYYDNSPAVLKSEKGLNV 809 + ++ + R E + LY+++A M P ++ L+ GL Sbjct: 764 RGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPS 823 Query: 810 NFIYIVPQANISSDTYRQLAQKALEKIKLPSGYYYEFSGESQYLEEAFKTLQYIVPVSVF 869 I SS L + KLP+G Y+++G S + +V +S Sbjct: 824 MEIQGEAAPGTSSGDAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISFV 881 Query: 870 IIFILIVFALKNLTNSLLCFFTLPFAFLGGLIFMNIMGFNMSVAALVGFLALLGVASETA 929 ++F+ + ++ + + +P +G L+ + V +VG L +G++++ A Sbjct: 882 VVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNA 941 Query: 930 IVMIIYLEDAFQKFIKTPLKEQNSAALKEAIMHGAVLRVRPKLMTFFSILASLIPIMYSH 989 I+++ + +D L E+ + EA + +R+RP LMT + + ++P+ S+ Sbjct: 942 ILIVEFAKD---------LMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISN 992 Query: 990 GTGSEIMKSIAAPMLGGMISSVVLTLFIIPTAYFVIK 1026 G GS ++ ++GGM+S+ +L +F +P + VI+ Sbjct: 993 GAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIR 1029
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 27.9 bits (62), Expect = 0.034 Identities = 17/88 (19%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Query: 144 FGSLVGSLVGTHFSFD---TQGMEFVMTAIFIVLFMEQYKRNTNHKN--AWLGIFIAVVC 198 G +G ++ + + M ++T F++ +++ R H + + + + +V Sbjct: 154 VGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVF 213 Query: 199 LALFGTEYFLLIALVLMVLALILFKKQL 226 LF T Y + L++ VL+ ++F K + Sbjct: 214 FMLFTTSYSISF-LIVSVLSFLIFVKHI 240
>cloacin#Cloacin signature. Length = 551 Score = 33.1 bits (75), Expect = 0.002 Identities = 21/99 (21%), Positives = 48/99 (48%), Gaps = 9/99 (9%) Query: 28 AKLSRSNEQLSDMLYKLNESLRIYQNVLSNNQDQL----KEIKKANSTLNSQRRFFNASQ 83 ++L +N+ L+D + ++ + R + ++ + ++A + +N+++ F+A+ Sbjct: 356 SELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAA 415 Query: 84 IRLMDTDALLKQSALELEKLQALEKRLKEGMEQERLIEE 122 D DA L SA+E K +K K+ + L +E Sbjct: 416 KEKSDADAAL-SSAMESRK----KKEDKKRSAENNLNDE 449
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 47.1 bits (112), Expect = 3e-09 Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 4/71 (5%) Query: 11 ALYGGSFDPLHKAHLAIIDQTLELLPFAKLIVLPAYQNPFKKPCFLDAQTRFKELERALK 70 A+Y GSFDP+ HL II++ L F ++ V +NP K+P F Q R +++ +A+ Sbjct: 3 AIYPGSFDPITFGHLDIIERGCRL--FDQVYVAVL-RNPNKQPMF-SVQERLEQIAKAIA 58 Query: 71 GMDRVLLSDFE 81 + + FE Sbjct: 59 HLPNAQVDSFE 69
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 50.6 bits (121), Expect = 2e-09 Identities = 51/346 (14%), Positives = 106/346 (30%), Gaps = 54/346 (15%) Query: 5 ILITGAYGMVGQNTALYFKKNKPDV-----------ALLTPKKSELY-----------LL 42 L+TGA G +G + + + V L + EL L Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62 Query: 43 DKDNVQAYLKEHKPTGIIHCAGRVGGIVANMNDLSTYMVENLLMGLYLFSSALDLGVKKA 102 D++ + + R + ++ + Y NL L + ++ Sbjct: 63 DREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 103 INLASSCAYPKFAPNPLKESDLLNGSLEPTNEGYALAKLSVMKYCEYVSAEKGVFYKTLV 162 + +SS Y P D ++ + YA K + S G+ L Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSL----YAATKKANELMAHTYSHLYGLPATGLR 177 Query: 163 PCNLYGEFDKFEEKIAHMIPGLIARMHTAKLKNEKEFVMWGDGTARREYLNAKDLARFIS 222 +YG + + P + T + K ++ G +R++ D+A I Sbjct: 178 FFTVYGPWGR---------PDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAII 228 Query: 223 LAYENIASIPS-----------------VMNVGSGVDYSIEEYYKMIAQVLDYKGAFVKD 265 + I + V N+G+ + +Y + + L + Sbjct: 229 RLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNML 288 Query: 266 LSKPVGMQQKLMDISK-QKALKWELEIPLEQGIKEAYEYYLKLLEV 310 +P + + D + + + E ++ G+K +Y +V Sbjct: 289 PLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYKV 334
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 87.9 bits (218), Expect = 2e-21 Identities = 46/180 (25%), Positives = 72/180 (40%), Gaps = 19/180 (10%) Query: 22 LITGVTGQDGSYLAEYLLNLGYEVHGLKRRSSSINTSRIDHLYEDLHSEHKRRFFLHYGD 81 L+TG G G ++++ LL G++V G+ + + S E L F H D Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQP---GFQFHKID 60 Query: 82 MTDSSNLIHLIATTKPTEIYNLAAQSHVKVSFETPEYTANADGIGTLRILEAMRILGLEN 141 + D + L A+ ++ + V+ S E P A+++ G L ILE R ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ- 119 Query: 142 KTRFYQASTSELYGEVLETPQNENTPF-------NPRSPYAVAKMYAFYITKNYREAYNL 194 AS+S +YG N PF +P S YA K + Y Y L Sbjct: 120 --HLLYASSSSVYGL------NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGL 171
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 31.7 bits (71), Expect = 0.004 Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 8/72 (11%) Query: 190 KEETKEEETITIGDNTNAMKIVKKDIQKGYRALKSSQ--RKWYCLGICSKKSKLSLMPEE 247 KE+ +EE+ I D A+ + Q + ALK + R + K+SK +MP E Sbjct: 365 KEKIREEKQKIILDQAKAL-----ETQYVHNALKRNPVPRNYNYYQAPEKRSK-HIMPSE 418 Query: 248 IFNDKQFTYFKF 259 IF+D FTYF F Sbjct: 419 IFDDGTFTYFGF 430
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 133 bits (336), Expect = 1e-40 Identities = 38/202 (18%), Positives = 73/202 (36%), Gaps = 4/202 (1%) Query: 40 QSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKTEHHF--VDFLNQDKHYAII 97 + K+A+ + G+ +A + + ++ PL+ E + VD + A Sbjct: 22 RDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAK 81 Query: 98 QRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQN 157 D +I+ +EA+ + + YV RE + ++ V + S+ R+ KT N Sbjct: 82 LHGDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARPEQDRWSRFYKTDN 141 Query: 158 SIYAQSHLEREVHI-VNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTP 216 Q+ L + V I +A V + + + + + Y D Sbjct: 142 PQSPQNILANRTDVFVEIKRVSFLGGNVAQVYFTKESVTGSNST-KTDAVATIKYKVDGT 200 Query: 217 DFDYASMPKNPTGFKVTRYSIT 238 KNP G++V Y Sbjct: 201 PSKEVDRFKNPLGYQVESYRAD 222