>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 33.9 bits (77), Expect = 6e-04 Identities = 37/144 (25%), Positives = 61/144 (42%), Gaps = 19/144 (13%) Query: 70 HPGIAAVHDYGESQLDGEGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRAL 129 HP +A VH G + L+M+ V+G + L+ + ++ G Sbjct: 190 HPNLANVHGMAVVPY-GNRKEEALLMDEVDGWRCSDTLRTLADSWKQGKINSEAYWGTIK 248 Query: 130 QVAH----------AAGLVHRDVKPGNILIT-PTGQVKITDFGIAKAVDAAPVTQTGMVM 178 +AH AG+VH D+KPGN++ +G+ + D G+ P G Sbjct: 249 FIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQP---KGF-- 303 Query: 179 GTAQYIAPEQALGH-DATPASDVY 201 T + APE +G+ A+ SDV+ Sbjct: 304 -TESFKAPELGVGNLGASEKSDVF 326
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.9 bits (69), Expect = 0.014 Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 6/71 (8%) Query: 423 PRATSPPGAQATRSPVPETGGPASPAP-PTTSASPTPSTNATPGPASSSPAGPTTTSQTL 481 P + P AQ P+PE +PA P + +P N P P + A P T Q Sbjct: 317 PGSAEAPNAQ----PLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPG 372 Query: 482 TALPGPPLQPG 492 T P P P Sbjct: 373 TR-PDSPAVPD 382
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.013 Identities = 14/55 (25%), Positives = 21/55 (38%) Query: 88 ADDSTLVLTDDYASARHARLTQRGSEWYVEDLGSTNGTYLDRAKVTTAVRVPIGT 142 +D T +DY R + + S GTY D+ K VR+ G+ Sbjct: 154 TEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDAGTYNDQNKYPAFVRLGSGS 208
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 35.1 bits (80), Expect = 8e-04 Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 33/170 (19%) Query: 94 QLPKIGADLEGIAAALAEAQ-KAGAARIATLDAQLKNISDLVVEAVALLNDKSLSPADRD 152 QL K A+ A A AEAQ KA A R DA + + D+V E AL ++ S +P+ + Sbjct: 61 QLKKTQAEQAARAKAAAEAQAKAKANR----DALTQRLKDIVNE--ALRHNASRTPSATE 114 Query: 153 ALHALINTC--ENDALRHTKA---ALADLQAIRNGY--ADGLQKSLNSLHAEGYDGAPLH 205 HA E++ LR KA A + +A + A+ +K + AE Sbjct: 115 LAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAE-------- 166 Query: 206 GVDADGVAPASPAQQAALDDIRRATNQAVLDQMAKVRAAQRALDKAMADV 255 +A A + AAL + +A V AQ+ L A ++V Sbjct: 167 TERQLKLAEAEEKRLAALSEEAKA-----------VEIAQKKLSAAQSEV 205
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 45.4 bits (107), Expect = 5e-07 Identities = 49/291 (16%), Positives = 73/291 (25%), Gaps = 34/291 (11%) Query: 71 NDELRKLKRAGMTDTARQAAEARVIEQARTRAVRRVESTIRYLHAVQSGARPPAPPRPTL 130 N E+ K + T I+ E R A PPAP P+ Sbjct: 982 NPEVEKRNQ---TVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVP---PPAPATPSE 1035 Query: 131 DAPGADLERTQVLPAV----GDAEHTAGPPAQQTPEARPRPTRRRAAEDEPAQLEETRVL 186 Q V DA T + EA+ + E + Sbjct: 1036 TTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSN------VKANTQTNEVAQSG 1089 Query: 187 PAIRDDAAAADASVPETPASEAPVPEAPETPAPEAPAAEAPVPEPLGEPTTRGRHHAPVP 246 ++ E E +T E P + V + T P Sbjct: 1090 SETKETQTTETKETATVEKEEKAKVETEKT--QEVPKVTSQVSPKQEQSETVQPQAEPAR 1147 Query: 247 EPVP----------EHVEPDIAAPAEAADLEQTQVIP---VVRRDEPVPEPPVVAPPEPA 293 E P + D PA+ Q + V V E P P Sbjct: 1148 ENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATT 1207 Query: 294 EEPADSGRHHAPADRDEPATESRPA---VADTETAQPRVEKPAPTTAFDNN 341 + +S + P +R + S P A T + T+ + N Sbjct: 1208 QPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTN 1258
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 81.9 bits (202), Expect = 5e-21 Identities = 61/221 (27%), Positives = 89/221 (40%), Gaps = 32/221 (14%) Query: 27 ITRAAVLASALEIIDRDGVDGLSMRRLGEAVGRDPMALYRHVPNKAAVLDGVVEMVFER- 85 + R +V+ +ALE+++ G+DGL+ R+L + +G + LY HV NK A+LD + + R Sbjct: 4 LNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILARH 63 Query: 86 --LSLDTTTPDWAAALRKLGHEF-------RDLARAHPNVVPLLVTRPLATPLGMRPPGI 136 SL W + LR F RD A+ H P Sbjct: 64 HDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGTRP--------DEKQY----- 110 Query: 137 LRHLEEVLTLLIGAGFTGEDALHVYRALFGFLYGHVLTELQEIVERPEETDHVLRLGLHR 196 +E L + GF+ D L+ A+ F G VL E QE + L Sbjct: 111 -DTVETQLRFMTENGFSLRDGLYAISAVSHFTLGAVL-EQQEHTAALTDRPAAPDENLPP 168 Query: 197 LPIDQFGHLRELAPVWASYDPLAELDRGLDILLSGLAVRLT 237 L LRE + S D GL+ L+ G V+LT Sbjct: 169 L-------LREALQIMDSDDGEQAFLHGLESLIRGFEVQLT 202
>PF07132#Harpin protein (HrpN) Length = 356 Score = 23.9 bits (51), Expect = 0.041 Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 1/45 (2%) Query: 10 KFEAAKGSAKKVFGRATGNTGMRAEGRAGQVKG-NAKQAGDKLND 53 KF A G K TGNT + A G G G +A GD++ + Sbjct: 304 KFMKAVGMIKSAVAGDTGNTNLHARGNGGASLGIDAAMIGDRIVN 348
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 34.2 bits (78), Expect = 8e-04 Identities = 20/101 (19%), Positives = 30/101 (29%) Query: 358 PQNYHPPTDLAPPPGTQIGPDGNLVATGPPLYNPNPSLADPNPPLPWWPWQIGPAPRVPG 417 P + PP + PPP + P+ P + P P P + + Sbjct: 57 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKR 116 Query: 418 TADPDDAPPPPPPSPAPPGPPPSPAPPGAVAPAAYGGNVGP 458 P ++ P P P P S A + GP Sbjct: 117 DVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGP 157 Score = 33.0 bits (75), Expect = 0.002 Identities = 21/119 (17%), Positives = 24/119 (20%), Gaps = 10/119 (8%) Query: 364 PTDLAPPPGTQIGPDGNLVATGPPLYNPNPSLADPNPPLPWWPWQIGPAPRVPGTADPDD 423 P P T + P PP P P P P P A Sbjct: 44 PAPAQPISVTMVAPA----DLEPPQAVQPPPEPVVEPEPE-----PEPIPEPPKEAPVVI 94 Query: 424 APPPPPPSPAPPGPPPSPAPPGAVAPAAYGGNVGPVGSQRERDQLGLITGQGRPASVAT 482 P P P P P P V P + V + Sbjct: 95 EKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAP-ARPTSSTATAATSKPVTS 152
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 9e-05 Identities = 24/136 (17%), Positives = 54/136 (39%), Gaps = 31/136 (22%) Query: 308 DALRVYPDVEVSLVPSPTVLMIGLPTGLRLVIDNAIANAVKHG-----NAGKIQLTVSSS 362 D L+ + P ++ + +P +++ + N +KHG GKI L + Sbjct: 238 DRLQFENQIN------PAIMDVQVP---PMLVQTLVENGIKHGIAQLPQGGKILLKGTKD 288 Query: 363 GEGVEIAIDDDGSGIPESERATVFERFARGSTAARSGSGLGLALVAQQ-AELHGGTAELQ 421 V + +++ GS ++ + +G GL V ++ L+G A+++ Sbjct: 289 NGTVTLEVENTGSLALKNT---------------KESTGTGLQNVRERLQMLYGTEAQIK 333 Query: 422 -NSPLGGTRLLLRLAG 436 + G ++ + G Sbjct: 334 LSEKQGKVNAMVLIPG 349
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.0 bits (106), Expect = 3e-08 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 1/73 (1%) Query: 2 ATATRERFLTAATGLFRRQGYSGTGLKQIVAESRAPLGSLYHFFPGGKQDLAVQAIAHTA 61 A TR+ L A LF +QG S T L +I + G++Y F K DL + + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHF-KDKSDLFSEIWELSE 67 Query: 62 ERYRELLDRVFAR 74 EL A+ Sbjct: 68 SNIGELELEYQAK 80
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 28.6 bits (63), Expect = 0.047 Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 3/77 (3%) Query: 184 VGAVTAEKLRAHGIATVADVAELSESTLGSMVGAAMGRQLYALSRNIDRRRVSTGVRRRS 243 VGA+ A I VA V + + + LG+ + MG + L N+ ++ G + + Sbjct: 410 VGAIVAAIAMVAVIVVVAVVGKGAAAKLGNALSKMMGETIKKLVPNVLKQLAQNGSKLFT 469 Query: 244 VGAQR---ALGRAGNTM 257 G QR LG G+ M Sbjct: 470 QGMQRITSGLGNVGSKM 486
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 69.7 bits (170), Expect = 7e-17 Identities = 28/123 (22%), Positives = 45/123 (36%), Gaps = 2/123 (1%) Query: 14 RAIRPTGDEREQAILATAERLLETRPFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSL 73 R + E Q IL A RL + + S+ ++AK AG++R Y++FK K + + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 74 LEPVIARADAEFDGAVQRLPTDPRRVWRNGIKAFFTAFSS--HRALARAATEALATSSEL 131 E + + P DP V R + + + R L Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 132 RAV 134 AV Sbjct: 123 MAV 125
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 27.0 bits (59), Expect = 0.029 Identities = 17/103 (16%), Positives = 34/103 (33%), Gaps = 9/103 (8%) Query: 4 PQDPTNSAADGAGD-----PPEKKPPAKAAKKTAKAPAKKAPAKKAPAKKAPAKKAPAK- 57 P P+N+ D PP P++ + A+ +++ + + A A + Sbjct: 1008 PSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNRE 1067 Query: 58 --KAPAKNTPTGGGQ-RADTNGDLTAAAKDAAAQAKSTVEAAD 97 K N +G T + + +TVE + Sbjct: 1068 VAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEE 1110
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 27.3 bits (60), Expect = 0.046 Identities = 21/107 (19%), Positives = 48/107 (44%), Gaps = 5/107 (4%) Query: 39 GVNDALAKLEEARANEDHAAIF-LNEKNLAFHLGGHVNHSIWWKNLSPDGGDKPTGELAA 97 V++A L++A+ N ++ I + ++F+ + + ++ + DK G+ Sbjct: 325 RVHEAEENLKKAQNNLLNSQIKDAVDATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIG 384 Query: 98 AIDDAFGSFDKFRA----QFSAAANGLQGSGWAVLGYDTVGSRLLTF 140 +++A +F+K++ +FS A + A + YD L F Sbjct: 385 NVNEALAAFEKYKDVLNKKFSKADRDAIFNALASVKYDDWAKHLDQF 431
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 37.8 bits (87), Expect = 7e-05 Identities = 29/76 (38%), Positives = 33/76 (43%), Gaps = 7/76 (9%) Query: 12 PGR-QGPPRQPGPEPSPVIPRPGGPAPSPHAPTQPLHRPPP--APPARP----APPARPA 64 PG + P QP PE SP PAP+ + T+P P P P A P P RP Sbjct: 317 PGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPD 376 Query: 65 PPASAIRPARPRRKRR 80 PA RP RK R Sbjct: 377 SPAVPDRPNGRHRKER 392
>PERTACTIN#Pertactin signature. Length = 922 Score = 38.2 bits (88), Expect = 7e-05 Identities = 19/48 (39%), Positives = 20/48 (41%) Query: 400 QAPPPPVDNGAPPPANPAPEAPPAPVPPPAAPPPPPPPAPEAPPGGPP 447 +APP P P P P P P PP PP PEAP PP Sbjct: 566 KAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPP 613 Score = 35.5 bits (81), Expect = 5e-04 Identities = 21/51 (41%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 401 APPPPVDNGAPPPANPAPEAPPAPVPPPAAPPPPPPPAPEA-PPGGPPPAG 450 A PP AP P PP P PP P PP PP + P PPAG Sbjct: 565 AKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAG 615 Score = 33.5 bits (76), Expect = 0.002 Identities = 18/40 (45%), Positives = 18/40 (45%) Query: 409 GAPPPANPAPEAPPAPVPPPAAPPPPPPPAPEAPPGGPPP 448 GA P P P P P P P P PP PP P PP P Sbjct: 564 GAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQR 603 Score = 33.2 bits (75), Expect = 0.003 Identities = 18/48 (37%), Positives = 18/48 (37%) Query: 398 PPQAPPPPVDNGAPPPANPAPEAPPAPVPPPAAPPPPPPPAPEAPPGG 445 PP P P P P P P PP P PP P P PP G Sbjct: 568 PPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAG 615 Score = 31.6 bits (71), Expect = 0.007 Identities = 16/46 (34%), Positives = 16/46 (34%) Query: 389 PGQQPVVTQPPQAPPPPVDNGAPPPANPAPEAPPAPVPPPAAPPPP 434 P QP P P PP P P PP P AP PP Sbjct: 568 PPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPP 613 Score = 31.2 bits (70), Expect = 0.010 Identities = 17/49 (34%), Positives = 17/49 (34%) Query: 393 PVVTQPPQAPPPPVDNGAPPPANPAPEAPPAPVPPPAAPPPPPPPAPEA 441 P PQ P P PP P P PP P P P PPA Sbjct: 569 PAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRE 617 Score = 28.9 bits (64), Expect = 0.047 Identities = 16/52 (30%), Positives = 18/52 (34%) Query: 388 LPGQQPVVTQPPQAPPPPVDNGAPPPANPAPEAPPAPVPPPAAPPPPPPPAP 439 L G + P P P PP P+ P P PP P P P P Sbjct: 562 LVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPP 613 Score = 28.9 bits (64), Expect = 0.047 Identities = 21/62 (33%), Positives = 23/62 (37%), Gaps = 1/62 (1%) Query: 366 AQSPSTQSGSAAAPEMPRNNQHLPGQQPVVTQPPQAPPPPVDNGAPPPANPAPEAPPAPV 425 A + + Q A P QPPQ P PP P P PEA PAP Sbjct: 553 AANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEA-PAPQ 611 Query: 426 PP 427 PP Sbjct: 612 PP 613
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.0 bits (67), Expect = 0.023 Identities = 39/169 (23%), Positives = 66/169 (39%), Gaps = 42/169 (24%) Query: 21 AINQSLQAGSPFQIERLAEAFHNAGRCTAEADHAFQDARKRFDAAWNHQNGDHPINDSDE 80 A N ++QA + RLA+A A + A+ AFQ+A +R E Sbjct: 118 ANNAAMQA--EDERLRLAKAEEKARKEAEAAEKAFQEAEQR----------------RKE 159 Query: 81 VQRVTKSLGAQSLQLPKIAADLEGIAASLAEAQKAGAQEIATLERELMFLDRLIGAAKED 140 ++R A++ + K+A E A+L+E KA EIA Sbjct: 160 IEREK----AETERQLKLAEAEEKRLAALSEEAKA--VEIA------------------Q 195 Query: 141 LKLNLPAAERAKLERLIKDAHADAVDDVRDAVKEMNSIRNAYSETLRKS 189 KL+ +E K++ IK ++ + EM ++ +E + S Sbjct: 196 KKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQAS 244
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.8 bits (80), Expect = 4e-04 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 4/89 (4%) Query: 116 LLADEINRTPPKTQAALLEAMEERQVSVEGEAQPLPEPF-IVTATQNPVEYEGTYQLPEA 174 L DEI P Q LL +++ + + G P+ IV AT ++ L Sbjct: 235 LFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFRE 294 Query: 175 QLDRFLLKLNVTLPP---REAEIAILHRH 200 L L + + LPP R +I L RH Sbjct: 295 DLYYRLNVVPLRLPPLRDRAEDIPDLVRH 323
>PERTACTIN#Pertactin signature. Length = 922 Score = 29.7 bits (66), Expect = 0.027 Identities = 20/48 (41%), Positives = 20/48 (41%) Query: 49 PPAYGPQSQYGAQYGAHFPGRYGAHYGPPPTYPPPGYPPAPAFGPPPG 96 PPA P Q G Q G P P P PP P APA PP G Sbjct: 568 PPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAG 615
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 47.5 bits (113), Expect = 1e-07 Identities = 26/116 (22%), Positives = 47/116 (40%), Gaps = 15/116 (12%) Query: 4 LATAGHVDHGKSTLLHRLT---------------GMWPDRLAEEQRRGLTIDLGFVWTEL 48 + HVD GK+TL L D E++RG+TI G + Sbjct: 6 IGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW 65 Query: 49 AGRRLAFVDVPGHERFVANMLAGVGPVPAVVFVVAATEGWMPQSEEHLAALDALRV 104 ++ +D PGH F+A + + + + +++A +G Q+ AL + + Sbjct: 66 ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 30.0 bits (67), Expect = 0.007 Identities = 35/201 (17%), Positives = 60/201 (29%), Gaps = 43/201 (21%) Query: 17 VAVTGSHPRAAAADVRIPLGGGAGIVVNGDTMCTLTTIGGDAAGDLIGFTSAHC-----G 71 + T + A +++ G + + +G D T+ H G Sbjct: 79 ITDTTNGHYAPVTYIQVEAPTG-------TFIASGVVVGKDTL-----LTNKHVVDATHG 126 Query: 72 GPGAQVAAEGAENA------GILGTMVAGND-NLDYAVIKFDPAKVTPVANFNGFLISGI 124 P A A A N G + D A++KF P + + Sbjct: 127 DPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIG------EVV 180 Query: 125 GPDPAFGEIACKQGRT---TGNSCGVTWG-MGQTPGTI------VMQVCG--QPGDSGAP 172 P + + TG M ++ G I MQ G+SG+P Sbjct: 181 KPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSP 240 Query: 173 V-TVNNQLVGMIHGAFSDNLP 192 V N+++G+ G + Sbjct: 241 VFNEKNEVIGIHWGGVPNEFN 261
>SECA#SecA protein signature. Length = 901 Score = 29.1 bits (65), Expect = 0.035 Identities = 27/98 (27%), Positives = 35/98 (35%), Gaps = 25/98 (25%) Query: 163 NTPGLR--WPDLALQGGRLNWAAV-RDALPRH-RGVSVLSGT--------------RRG- 203 N P +R PDL A+ D R +G VL GT + G Sbjct: 415 NRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGI 474 Query: 204 -HEVDAGPVHA-----VVDAGRRGAVSVICDLPRRFTD 235 H V HA V AG AV++ ++ R TD Sbjct: 475 KHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTD 512
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 35.7 bits (82), Expect = 3e-04 Identities = 30/97 (30%), Positives = 44/97 (45%) Query: 214 PRPQQPAPLRRERPRYQEPPGPTEPRFEPRYQPPPAAAATPPPPETPPEPPREPQPEPQP 273 P P QP + P EPP +P EP +P P P PP+ P +P+P+P+P Sbjct: 39 PAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 98 Query: 274 EPQPQPQGRDWQPVGAEGQWLPPGSPGSNWAGADAES 310 +P+P + ++ + P SP N A A S Sbjct: 99 KPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTS 135 Score = 30.0 bits (67), Expect = 0.015 Identities = 18/101 (17%), Positives = 32/101 (31%), Gaps = 1/101 (0%) Query: 241 EPRYQPPPAAAATPPPPETPPEPPREPQ-PEPQPEPQPQPQGRDWQPVGAEGQWLPPGSP 299 P+ PP P PE P P + P +P+P+P+ + + Q P Sbjct: 57 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKP 116 Query: 300 GSNWAGADAESTGGRRRARHSGADEAWDGMPVEPVPPPPYA 340 + + E+T R + + P + Sbjct: 117 VESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALS 157 Score = 29.6 bits (66), Expect = 0.024 Identities = 27/126 (21%), Positives = 42/126 (33%), Gaps = 6/126 (4%) Query: 195 PGRHDETAIIDVPEEPLMPPRPQQPAPLRRERPRYQEPPGPTEPRFEPRYQPPPAAAATP 254 P ++ V L PP+ QP P P + P P P+ P P Sbjct: 39 PAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKP-----K 93 Query: 255 PPPETPPEPPREPQPEPQPEPQPQPQGRDWQPVGAEGQWLPPGSPGSNWAGADAESTGGR 314 P P+ P+P ++ Q +P+ + +P + R P S + S Sbjct: 94 PKPKPKPKPVKKVQEQPKRDVKPV-ESRPASPFENTAPARLTSSTATAATSKPVTSVASG 152 Query: 315 RRARHS 320 RA Sbjct: 153 PRALSR 158
>PF03309#Bvg accessory factor Length = 271 Score = 369 bits (950), Expect = e-132 Identities = 236/271 (87%), Positives = 255/271 (94%) Query: 1 MLLAIDVRNTHTVVGLISGSKEHAKVVQQWRIRTESEITADELALTIDGLIGDDSERLTG 60 MLLAIDVRNTHTVVGLISGS +HAKVVQQWRIRTE E+TADELALTIDGLIGDD+ERLTG Sbjct: 1 MLLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDGLIGDDAERLTG 60 Query: 61 AAALSTVPSVLHEVRLMLDQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAF 120 A+ LSTVPSVLHEVR+ML+QYWP+VPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAA+ Sbjct: 61 ASGLSTVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAY 120 Query: 121 HRFQSPAIVIDFGSSICVDVVSAKGEFLGGAIAPGLQVSSDAAAARSAALRRVELARPRS 180 H++ + AIV+DFGSSICVDVVSAKGEFLGGAIAPG+QVSSDAAAARSAALRRVEL RPRS Sbjct: 121 HKYGTAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELTRPRS 180 Query: 181 VIGKNTVECMQAGAVFGFAGLVDGLVGRIREDVPGFGGDDVAIVATGHTAPLLLPELDTV 240 VIGKNTVECMQAGAVFGFAGLVDGLV RIR+DV GF G DVA+VATGHTAPL+LP+L TV Sbjct: 181 VIGKNTVECMQAGAVFGFAGLVDGLVNRIRDDVDGFSGADVAVVATGHTAPLVLPDLRTV 240 Query: 241 SHYDQHLTLHGLRLVFERNRDAQRGRLKTAR 271 HYD+HLTL GLRLVFERNR QRG+LK AR Sbjct: 241 EHYDRHLTLDGLRLVFERNRANQRGKLKPAR 271
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.014 Identities = 30/138 (21%), Positives = 53/138 (38%), Gaps = 22/138 (15%) Query: 518 IIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFLFGDDDAL 577 ++G+ A++ + + + R + + + G SG GK +++AL ++ + Sbjct: 139 LVGRSAAMQEIYRVLARL-------MQTDLTLMITGESGTGKELVARALHDYGKRRNGPF 191 Query: 578 IQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKP--FS-----VVLFDEIEKA 630 + I+M S LFG E G T R F + DEI Sbjct: 192 VAINMAAIPRDLIESELFGH--------EKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 631 HQEIYNSLLQVLEDGRLT 648 + LL+VL+ G T Sbjct: 244 PMDAQTRLLRVLQQGEYT 261
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 30.3 bits (68), Expect = 0.017 Identities = 19/86 (22%), Positives = 35/86 (40%), Gaps = 6/86 (6%) Query: 55 LSGVVAFLGAVLVLAKLCDDEGLFEAAGAAIARGRVGSAGMLRRVFVIASAITAVLSLDA 114 +SG+++ + A +L+ D AAG + +G+ G ++IA LS A Sbjct: 245 VSGILSAISASFILSNADADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLSTSA 304 Query: 115 AVVLLTPVVLAAVRRQRTAVRPYAYA 140 A L + A+ P ++ Sbjct: 305 AAAGLIASAVTL------AISPLSFL 324
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.026 Identities = 14/40 (35%), Positives = 16/40 (40%), Gaps = 7/40 (17%) Query: 18 AATAVAKTAGAAPPPALPAP-------PPSPGIGVDHENG 50 + TA A AG PP P P PG G D E+ Sbjct: 389 SPTAAAGGAGGGEPPKKRDPSAGAGTDPGGPGGGDDGEDP 428
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 32.7 bits (74), Expect = 0.002 Identities = 16/55 (29%), Positives = 19/55 (34%), Gaps = 2/55 (3%) Query: 95 QNGPNNA--PQGGQNNPPQGGPNNAPQGGQNNPPQGGPNNAPQNGPNNPPQGGQN 147 G N P+GG + P P+N Q N Q N NPP Q Sbjct: 318 SAGLNIIAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPPNSAQK 372 Score = 32.3 bits (73), Expect = 0.003 Identities = 20/71 (28%), Positives = 26/71 (36%), Gaps = 10/71 (14%) Query: 118 PQGGQNNPPQGGPNNAPQNGPNNPPQGGQNEPGGQYPPNQHGQNPPQNGQN---QPPYDH 174 P+GG + P P+N QN N + Q N NPP + Q QP Sbjct: 327 PEGGYKDKPNDKPSNTTQNNAKN-----DKQESSQNNSNTQVINPPNSAQKTEIQPT--Q 379 Query: 175 DQNPPTPGGPT 185 + P GG Sbjct: 380 VIDGPFAGGKN 390 Score = 31.9 bits (72), Expect = 0.004 Identities = 23/91 (25%), Positives = 31/91 (34%), Gaps = 6/91 (6%) Query: 76 TPPQGGQNNPPPNGPNNPPQNGPNNAPQGGQNNPPQGGPNNAPQGGQNNPPQGGPNNAPQ 135 PP+GG + P + P+N QN N Q N N P Q Q P Sbjct: 325 APPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPPNSAQKTEIQ------PT 378 Query: 136 NGPNNPPQGGQNEPGGQYPPNQHGQNPPQNG 166 + P GG+N N + + G Sbjct: 379 QVIDGPFAGGKNTVVNINRINTNADGTIRVG 409
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 110 bits (277), Expect = 3e-30 Identities = 36/136 (26%), Positives = 63/136 (46%) Query: 13 ARVLVVDDEANIVELLSVSLKFQGFEVHTATNGAQALDRAREARPDAVILDVMMPGMDGF 72 A +LV DD+A I +L+ +L G++V +N A D V+ DV+MP + F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 73 GVLRRLRADGIDAPALFLTARDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRAG 132 +L R++ D P L ++A+++ I G DY+ KPF L E++ + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 133 KGGAEPRSARLTFADI 148 + ++ + Sbjct: 124 RRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 7e-04 Identities = 21/104 (20%), Positives = 34/104 (32%), Gaps = 24/104 (23%) Query: 370 LIANALQH----TPESADVTVRVGTDGDDAVLEVADRGPGMNEQDASRVFERFYRTDSSR 425 L+ N ++H P+ + ++ D LEV + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------- 309 Query: 426 ARASGGTGLGLSIV-ESLVRAHGGTVGVTTAPGQGC-CFRVTLP 467 TG GL V E L +G + + QG V +P Sbjct: 310 -----STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 49.6 bits (118), Expect = 7e-10 Identities = 27/127 (21%), Positives = 46/127 (36%), Gaps = 3/127 (2%) Query: 15 ILAEAARLVAERGAERVSLRELARCAGVSHAAPAHHFTDRRGLFTALATQGFELLTQALA 74 IL A RL +++G SL E+A+ AGV+ A HF D+ LF+ + + + Sbjct: 16 ILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELEL 75 Query: 75 DARGDFADAALAYVQFALDHPGHY-QVMFNRSLLDASDGGLAAAEAAAGAELSRGVATLR 133 + + F L+ ++ L H R LL E + + Sbjct: 76 EYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEII--FHKCEFVGEMAVVQQAQRNL 133 Query: 134 DPHARAD 140 + Sbjct: 134 CLESYDR 140
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 134 bits (339), Expect = 2e-36 Identities = 85/426 (19%), Positives = 173/426 (40%), Gaps = 27/426 (6%) Query: 51 IMAVLDSTVVAVAQRTFIAQFGVNQAIVSWTIAGYMLAFATVIPITGWAADRFGTKRLFM 110 +VL+ V+ V+ F A +W +ML F+ + G +D+ G KRL + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 111 GSVLIFTLGSLLCAVAPNIL-LLILFRVVQGVGGGMLLPLSFVILTREAGPKRVGRLMAV 169 ++I GS++ V + LLI+ R +QG G L V++ R + G+ + Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 170 GGIPILLGPIGGPILGGWLIGAYGWKWIFLINLPIGLTAFALAALLFPKDRSAPSEALDI 229 G + +G GP +GG + W +L+ +P+ + K DI Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 230 TGALLLSPGVAIFLCGVCSIPGRHTVADRYVLVPALVGLVLIAAFILHAWYRTEHPLIDL 289 G +L+S G+ F+ T L+ +++ ++ I + P +D Sbjct: 202 KGIILMSVGIVFFMLFT-------TSYSISFLIVSVLSFLIFVKHIR----KVTDPFVDP 250 Query: 290 RLFRN-PVVTQVNVTLLVFAAASVGVGLLVPSYFQIVGHETPMQSG-LHMLPIGVGAVLT 347 L +N P + V ++F G +VP + V + + G + + P + ++ Sbjct: 251 GLGKNIPFMIGVLCGGIIFGTV-AGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 348 MPLGGAVMDKHGPGKIVLTGLPLMAVG---LAVFTYGVARQAAYSPVLVCGLAIMGLGIG 404 +GG ++D+ GP ++ G+ ++V + + V V G G+ Sbjct: 310 GYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG------GLS 363 Query: 405 LTTTPLSAALMQALAPHQVARGTTLISVNQQVGGSIGAALMAVILTNQF-NRNPALMAAN 463 T T +S + +L + G +L++ + G A++ +L+ ++ M + Sbjct: 364 FTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVD 423 Query: 464 EAAGMH 469 ++ ++ Sbjct: 424 QSTYLY 429
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 124 bits (312), Expect = 9e-33 Identities = 80/412 (19%), Positives = 170/412 (41%), Gaps = 21/412 (5%) Query: 46 VCILATVMAILDVTVVSVAQRTFIDQFSSSQAVVAWTMTGYTLALATVIPITGWAADRFG 105 +CIL + ++L+ V++V+ + F+ A W T + L + + G +D+ G Sbjct: 19 LCIL-SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLG 77 Query: 106 TKRLFIGSVLAFMLGSLLCALAANVLQLIVF-RVVQGIGGGMLLPLGFMILTREAGPRRL 164 KRL + ++ GS++ + + L++ R +QG G L +++ R Sbjct: 78 IKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENR 137 Query: 165 GRLMSILSIPMLLAPIGGPILGGWLIDTSSWRWIFLINVPIGLLTVALAAVVFPRDHPAR 224 G+ ++ + + GP +GG + W +L+ +P+ + + + Sbjct: 138 GKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRI 195 Query: 225 SETFDAVGVLLLSPGLATFLFAVSSIPGRGTVADRHVLIPAAMGLTLIAGFVGHAWHRAD 284 FD G++L+S G+ F+ T LI + + + FV H + Sbjct: 196 KGHFDIKGIILMSVGIVFFMLFT-------TSYSISFLIVSVLSFLI---FVKHI-RKVT 244 Query: 285 HPLIDLRLFRN-PVLTHANVTMLVFATAFFGAGLLLPSYFQQVLHQTPMQAG-VHMIPQG 342 P +D L +N P + ++F T G ++P + V + + G V + P Sbjct: 245 DPFVDPGLGKNIPFMIGVLCGGIIFGT-VAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 343 LGAMLTVRLTGPLVDRQGPGKVVLVGIALITAGLGAFAFGVARQAPYLPTLLAGLAITGL 402 + ++ + G LVDR+GP V+ +G+ ++ +F + + T+ + Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASF-LLETTSWFMTI--IIVFVLG 360 Query: 403 GMGCTMMPLSVASVQALAPHQIARGTTLMSVSHQVGGSMGTALMSMILTNQF 454 G+ T +S +L + G +L++ + + G A++ +L+ Sbjct: 361 GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.9 bits (77), Expect = 9e-04 Identities = 23/124 (18%), Positives = 43/124 (34%), Gaps = 5/124 (4%) Query: 6 KPPHDSATSDEDVKALLEEAEAEAAEAEALAAAARARARAARLRREAQAQAAKAAAETSE 65 DV ++ E A EA + E A+ +K ++T E Sbjct: 995 TNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSET--TETVAENSKQESKTVE 1052 Query: 66 ADEHAADDEAAETDDEVSDSVEATDADDTETTQAETKEAAKETEPKEEAAEETAEDAESE 125 +E A + A+ + ++ A+ T E ++ ET+ + + E E Sbjct: 1053 KNEQDATETTAQNREVAKEAKSNVKAN---TQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 126 SKAR 129 KA+ Sbjct: 1110 EKAK 1113
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 132 bits (332), Expect = 8e-40 Identities = 79/248 (31%), Positives = 122/248 (49%), Gaps = 19/248 (7%) Query: 2 KTAVVTGGGSGIGLAVVERLRADGLNVASIDLRPSDAEL-------------AFTADVTD 48 K A +TG GIG AV L + G ++A++D P E AF ADV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 49 RSQVDAALSAIRAQLGPVTVLVNAAGLDGFKKFNNITFEDWQRVIDVNLNGVFHTTQAVL 108 + +D + I ++GP+ +LVN AG+ ++++ E+W+ VN GVF+ +++V Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 109 PDMIEAGWGRIVNISSSSTHSGAPYMSHYVAAKSAVNGLTKSLALEYGPKGITVNAVPPG 168 M++ G IV + S+ M+ Y ++K+A TK L LE I N V PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 169 FIDTPMLRA------AEKNGFLGDIEETIARTPVRRMGTPQDIAAACAFLVSEEAGYITG 222 +T M + + G +E P++++ P DIA A FLVS +AG+IT Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 223 QILGVNGG 230 L V+GG Sbjct: 249 HNLCVDGG 256
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.2 bits (65), Expect = 0.010 Identities = 17/84 (20%), Positives = 24/84 (28%), Gaps = 6/84 (7%) Query: 126 LQKSVDPSKILYSEPRLAPGGEGPKPGPPEIPPAVSAYTGLPGDPVGPPGAEPPARIPGA 185 P ++ EP P E PK P I P P + + Sbjct: 64 QAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK------PKPKPKPKPVKKVEQPKRD 117 Query: 186 AMPLPPPPSTPMPPPPPPEPGVSG 209 P+ P++P P P S Sbjct: 118 VKPVESRPASPFENTAPARPTSST 141
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 32.7 bits (74), Expect = 0.003 Identities = 25/80 (31%), Positives = 37/80 (46%) Query: 95 GQTSLLGSMHVELNTPLGQQGSGRLQPGATIPLSRSSAYPSTEQTLSSLGAVVNGGGLGQ 154 GQ SL+G+ P Q G QP P + + P+ + ++ A VN GG+G Sbjct: 562 GQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVGL 621 Query: 155 IGEIIHNFSAALSGREGAVR 174 + + S ALS R G +R Sbjct: 622 ASTLWYAESNALSKRLGELR 641 Score = 28.9 bits (64), Expect = 0.048 Identities = 23/62 (37%), Positives = 25/62 (40%), Gaps = 3/62 (4%) Query: 365 GPGPRQIVGDPLPGPPPGAAPLPGPPPGAAPLPGPPPGAASLPDAGLGQTPPAATAPTEG 424 G G +VG P P P AP PGP P P P P A P + AA A Sbjct: 560 GNGQWSLVGAKAP-PAPKPAPQPGPQPPQPPQPQPEAPAPQPPAG--RELSAAANAAVNT 616 Query: 425 GG 426 GG Sbjct: 617 GG 618
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 34.6 bits (79), Expect = 8e-04 Identities = 12/89 (13%), Positives = 18/89 (20%), Gaps = 1/89 (1%) Query: 460 AAVPPVPS-SGPPALAPMSRMSADLPPIAPLDVPTPTELPPPPPPPPAPAAPDQVDGAAP 518 A + P + PP + P P + P E P P P P Sbjct: 58 ADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRD 117 Query: 519 QAAPSAFAGKASKPAPSVVVAKYDPRTGR 547 + + Sbjct: 118 VKPVESRPASPFENTAPARPTSSTATAAT 146 Score = 33.4 bits (76), Expect = 0.002 Identities = 24/119 (20%), Positives = 34/119 (28%), Gaps = 6/119 (5%) Query: 435 LPPGAVPRGAPAGPRGENPPPGSVGAAVPPVPSSGPPALAPMSRMSADLPPIAPLDVPTP 494 LP A P + PP +V PP P P P + P AP+ + P Sbjct: 43 LPAPAQPISVTMVAPADLEPPQAVQP--PPEPVVEPE---PEPEPIPEPPKEAPVVIEKP 97 Query: 495 TELPPPPPPPPAPAAPDQVDGAAPQAAPSAFAGKASKPAPSVVVAKYDPRTGRYVGPDG 553 + P P P P P + A + + PA + Sbjct: 98 -KPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVAS 155
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 59.3 bits (143), Expect = 2e-13 Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 2 LDAALDLFAANGVSGTSLQMIADAVGITKAAVYHQFRTKEQIVIAVTERELGRLVPALEE 61 LD AL LF+ GVS TSL IA A G+T+ A+Y F+ K + + E + E Sbjct: 17 LDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELE 76 Query: 62 AEAHDDG---PQARDALLVRVIEMAVRDRR 88 +A G R+ L+ + +RR Sbjct: 77 YQAKFPGDPLSVLREILIHVLESTVTEERR 106
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.8 bits (134), Expect = 1e-11 Identities = 28/156 (17%), Positives = 60/156 (38%), Gaps = 10/156 (6%) Query: 16 ARRIGAPDAKNRGLLLDAAERLMLEEGYAAVTSRRLASRAGLKPQLVHYYFRTMEELFLE 75 AR+ + R +LD A RL ++G ++ + +A AG+ ++++F+ +LF E Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 76 VFRRRAEEGLAVQAQALQSDQP--LWAVWRFGTDPAFTQISME-----FMALANHRKDMR 128 ++ + Q+ P +V R E M + H+ + Sbjct: 62 IWELSESN-IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 129 AEIAYYA--ERFRDEQQRAVAAALERYGVQNKDVPP 162 E+A +R + ++ ++ K +P Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPA 156
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 63.1 bits (153), Expect = 1e-14 Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 6/109 (5%) Query: 1 MGRPRSDTRERIQQVARELFSQRGVQRTSLQDIADRLGITKPALYYHFPSREDLVRSILV 60 + +TR+ I VA LFSQ+GV TSL +IA G+T+ A+Y+HF + DL I Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 PLIEEGERFVAEHESREHTE----ARELLEGYFD--FHYRHRRDLVLLL 103 E++++ + RE+L + RR L+ ++ Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEII 113
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 32.5 bits (74), Expect = 6e-04 Identities = 8/45 (17%), Positives = 21/45 (46%) Query: 31 WLAQQGFSSAQPEVVADGSPVGEALRKAIDDDVDVILTSGGTGIA 75 ++ SS++ + + + + + L + +D+I +GG I Sbjct: 298 YVLTYNPSSSKIHIKKEKARIKDVLSFYLGRKIDIIKCAGGDLIH 342
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 36.9 bits (85), Expect = 4e-05 Identities = 17/65 (26%), Positives = 19/65 (29%), Gaps = 1/65 (1%) Query: 140 VPQAPPADAPPPAPVQLASFD-RPAPPDAPAPDAPPPAPADLPPAPPADATPPAPPADAP 198 AP PP A P P P P+ P AP + P P P Sbjct: 53 TMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVE 112 Query: 199 APDGD 203 P D Sbjct: 113 QPKRD 117 Score = 29.2 bits (65), Expect = 0.012 Identities = 20/100 (20%), Positives = 26/100 (26%), Gaps = 1/100 (1%) Query: 126 VPAPAGLDAPGVNGVPQAPPADAPPPAPVQLASFDRPAPPDAPAPDAPPPAP-ADLPPAP 184 A P V P+ P PP + +P P P P P D+ P Sbjct: 63 PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVE 122 Query: 185 PADATPPAPPADAPAPDGDFHGFVPAGMPDHVSEAGYTQR 224 A+P A A + S R Sbjct: 123 SRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSR 162
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 36.9 bits (85), Expect = 1e-04 Identities = 25/96 (26%), Positives = 31/96 (32%), Gaps = 2/96 (2%) Query: 49 VVGPAPTANATPCGAPEANVD-PPAAPPAMPAPQPVVQPPTGRRPTHTNDQAPLPKLGPL 107 VV P P P EA V P P P+PV + +R + P Sbjct: 73 VVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENT 132 Query: 108 ISSLLKPSAPGRQYSAPVHPRAEGPGP-DPSAPMYP 142 + S S PV A GP + P YP Sbjct: 133 APARPTSSTATAATSKPVTSVASGPRALSRNQPQYP 168 Score = 29.9 bits (67), Expect = 0.022 Identities = 21/93 (22%), Positives = 24/93 (25%), Gaps = 2/93 (2%) Query: 122 SAPVHPRAEGPGPD--PSAPMYPQAEVLPPGPNPPTPGGAVPPNANQLRPNAAPMPQPQP 179 VH E P P S M A++ PP P P V P P P Sbjct: 34 YTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVV 93 Query: 180 QPQPAPGPPPPSIAGAPTSLVDWVTGPNGPNKT 212 +P P P P P Sbjct: 94 IEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPA 126 Score = 29.6 bits (66), Expect = 0.025 Identities = 19/99 (19%), Positives = 29/99 (29%), Gaps = 7/99 (7%) Query: 123 APVHPRAEGPGPDPSAPMYPQA------EVLPPGPNPPTPGGAVPPNANQLRPNAAPMPQ 176 A P P+P P+ + P P P V Q + + P+ Sbjct: 65 AVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVE-QPKRDVKPVES 123 Query: 177 PQPQPQPAPGPPPPSIAGAPTSLVDWVTGPNGPNKTLQR 215 P P P+ + A + VT + L R Sbjct: 124 RPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSR 162
>cloacin#Cloacin signature. Length = 551 Score = 30.5 bits (68), Expect = 0.007 Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 12/67 (17%) Query: 152 FPTDLDDVASRLNAAARLTIAVQRARQDREARIEGELGQQPGYIEQLEYDAAHPENAVEV 211 FP D A ++ + L+ + RQD E R Q E+DA HP A E Sbjct: 274 FPKDSGHNAVYVSVSDVLSPDQVKQRQDEENR------------RQQEWDATHPVEAAER 321 Query: 212 DGEQASA 218 + E+A A Sbjct: 322 NYERARA 328
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 108 bits (271), Expect = 2e-30 Identities = 73/254 (28%), Positives = 118/254 (46%), Gaps = 10/254 (3%) Query: 8 LDDKVAVITGAGRGLGAAIAVAFAEAGADVLIASRTESQLEAVAEQVRAAGRRAHVVAAD 67 ++ K+A ITGA +G+G A+A A GA + +LE V ++A R A AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 68 LAHPESTAELAARAVEAFGKLDIVVNNVGGTMPNTLLTTSTKDLKDAFTFNVATAHALTV 127 + + E+ AR G +DI+VN G P + + S ++ + F+ N + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 128 AAVPLMLEHSGGGNIIKITSTMGRLAGRGFAAYGTAKAALSHYTRLTALDLCPR-IRVNA 186 + M++ G+I+ + S + AAY ++KAA +T+ L+L IR N Sbjct: 126 SVSKYMMDRR-SGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 187 IAPGSILTSA-----LDVVASNDELRAPMEK---ATPLRRLGDPVDIAAAAVYLASPAGE 238 ++PGS T D + ++ +E PL++L P DIA A ++L S Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 239 FLTGKTLEVDGGLT 252 +T L VDGG T Sbjct: 245 HITMHNLCVDGGAT 258
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 30.5 bits (69), Expect = 0.008 Identities = 12/40 (30%), Positives = 19/40 (47%), Gaps = 2/40 (5%) Query: 134 TLDLDPPEITDEVRDYAA--PSFAPGRPLIEVLRDLASRI 171 + +P E+ D ++ Y P GRP E L + +RI Sbjct: 335 AISFNPEEVADNMKKYGGFIPGIRAGRPTAEYLSYVLNRI 374
>PERTACTIN#Pertactin signature. Length = 922 Score = 32.0 bits (72), Expect = 0.004 Identities = 18/48 (37%), Positives = 18/48 (37%) Query: 11 PPEPPPGYGPPPGYGTPPGYGTPPPPPPGYGPPPGYGAPPPGYGPPPG 58 PP P P P P G P PP PP PP P PP G Sbjct: 568 PPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAG 615 Score = 30.1 bits (67), Expect = 0.013 Identities = 18/47 (38%), Positives = 18/47 (38%) Query: 8 PGTPPEPPPGYGPPPGYGTPPGYGTPPPPPPGYGPPPGYGAPPPGYG 54 P P P PG P P PP PP PP P AP P G Sbjct: 569 PAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAG 615 Score = 29.7 bits (66), Expect = 0.018 Identities = 17/51 (33%), Positives = 20/51 (39%) Query: 2 SQPPEYPGTPPEPPPGYGPPPGYGTPPGYGTPPPPPPGYGPPPGYGAPPPG 52 ++ P P P+P P GP P P PP PP P PP G Sbjct: 565 AKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAG 615 Score = 28.5 bits (63), Expect = 0.037 Identities = 21/69 (30%), Positives = 22/69 (31%), Gaps = 4/69 (5%) Query: 21 PPGYGTPPGYGTPPPPPPGYGPPPGYGAPPPGYGPPPGYGPPPGFGGP----PKPAFSVG 76 G + G PP P P P P G PP PP PP P P G Sbjct: 556 GNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAG 615 Query: 77 EAFGWAWNA 85 A NA Sbjct: 616 RELSAAANA 624
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 30.1 bits (67), Expect = 0.038 Identities = 31/131 (23%), Positives = 52/131 (39%), Gaps = 14/131 (10%) Query: 526 TGAGESARAAVTDVQKIAKTLWVHRVNVESGEFVEGDTVIAAVDPQWRRGATQGHSGTHM 585 T +A VQK + + +S F+ A + + + Q H+ Sbjct: 120 TVVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFL------AQLSLPAQLASQQSGVPHHL 173 Query: 586 V--HAALRQVLGPNAVQAGSLNRPGYLRF----DFNWQGPLTEEQRTQIEEVTNQAVQAD 639 + AAL G ++ + P Y F NW+GP+TE T+ E + V+A Sbjct: 174 ILAQAALESGWGQRQIRRENGE-PSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAK 232 Query: 640 FEVH-TFTEQL 649 F V+ ++ E L Sbjct: 233 FRVYSSYLEAL 243
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 44.4 bits (105), Expect = 2e-08 Identities = 37/130 (28%), Positives = 57/130 (43%), Gaps = 9/130 (6%) Query: 12 WLAVLSCYDIRQHRLPNALTLTGAAAILAAAGLAG--RGPSALAGAAA----LAAIYLLV 65 L L+ D+ + LP+ LTL L L G A+ GA A L ++Y Sbjct: 143 VLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMAGYLVLWSLYWAF 202 Query: 66 HAV-APGGMGAGDVKLALGVGALTGCGGV-GVWFLAALAAPLLTVLVGVLARVRRAGPTV 123 + GMG GD KL +GA G + V L++L + + + +L ++ P + Sbjct: 203 KLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLILLRNHHQSKP-I 261 Query: 124 PHGPSLCLAA 133 P GP L +A Sbjct: 262 PFGPYLAIAG 271
>PF06580#Sensor histidine kinase Length = 349 Score = 39.5 bits (92), Expect = 2e-05 Identities = 18/105 (17%), Positives = 36/105 (34%), Gaps = 28/105 (26%) Query: 363 LVDNAVRHAVS------CVAIEVGSRDGTAVLTVGDDGPGIPPAQRSRVFERFVRLDTDR 416 LV+N ++H ++ + ++ +GT L V + G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK----------------- 305 Query: 417 ARSGGGAGLGLAIVAE-VVAAHGG--TVTIGDRPGGGTTLTVALP 458 + G GL V E + +G + + ++ G V +P Sbjct: 306 -NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNA-MVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.6 bits (217), Expect = 3e-22 Identities = 29/129 (22%), Positives = 58/129 (44%), Gaps = 1/129 (0%) Query: 2 KVLLVEDEPRLAATVARGLKAEGFVVVTVGNGVDGLAEATENPFDIVILDIMLPGRSGYE 61 +L+ +D+ + + + L G+ V N D+V+ D+++P + ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRRMRSNNVWTPVLMLTAKDGEYDETDAFDLGADDYLTKPFSFRVLVARL-RALVRRGA 120 +L R++ PVL+++A++ A + GA DYL KPF L+ + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 PERPVVLTA 129 + + Sbjct: 125 RPSKLEDDS 133
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.3 bits (78), Expect = 4e-04 Identities = 18/66 (27%), Positives = 23/66 (34%), Gaps = 10/66 (15%) Query: 27 VVRPG----EILVLTGPSGCGKSTVLRALAGLLTPDGGRVLADGVPVTGTSGDRAMVFQD 82 V+ PG +VL G G GKST++ L GL +D GT D Sbjct: 588 VMEPGCKFDYSVVLEGTGGIGKSTLINTLVGL------DFFSDTHFDIGTGKDSYEQIAG 641 Query: 83 NALLPW 88 Sbjct: 642 IVAYEL 647
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 77.2 bits (190), Expect = 3e-17 Identities = 71/342 (20%), Positives = 131/342 (38%), Gaps = 29/342 (8%) Query: 32 VLLGALDAYVVVTIMRDIMTDVHIPINQLQRITWIITMYLLGYIAAMPLLGRASDRFGRK 91 L+ V+ + DI D + P W+ T ++L + + G+ SD+ G K Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPAST---NWVNTAFMLTFSIGTAVYGKLSDQLGIK 79 Query: 92 LVLQVSLALFMVGSVVTALAGHWGDFHLLIGGRTIQGVASGALLPVTLALGADLWAQRNR 151 +L + + GSV+ GH F LLI R IQG + A + + + A + NR Sbjct: 80 RLLLFGIIINCFGSVI-GFVGH-SFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENR 137 Query: 152 AGVLGGIGAAQELGSVLGPLYGIFIVFLFHDWRYVFWINVPLTLIAMVMIQFSLPSHEKV 211 G IG+ +G +GP G I H W Y+ +P+ I V L E Sbjct: 138 GKAFGLIGSIVAMGEGVGPAIGGMIAHYIH-WSYLL--LIPMITIITVPFLMKLLKKEV- 193 Query: 212 EQPEKVDLVGGVLLAVALGLAVIGLYNPEPDGKQILPSYGLPLVLGAVVVGILFLLWERF 271 D+ G +L++V + ++ SY + ++ +V+ ++F+ R Sbjct: 194 RIKGHFDIKGIILMSVGIVFFMLF-----------TTSYSISFLIVSVLSFLIFVKHIRK 242 Query: 272 ARTRLIEPAGVHFRPFLAALGASLFAGAALMVTLVDVELFGQGVLG---QDQTQAAGLLL 328 ++P PF+ + G + T+ ++ Q T G ++ Sbjct: 243 VTDPFVDPGLGKNIPFMIG----VLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI 298 Query: 329 WFLIALPIG--AVLGGWIATRVGDRAMTFVGLLIAAYGYWLI 368 F + + +GG + R G + +G+ + + Sbjct: 299 IFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTA 340
>PRPHPHLPASEC#Prokaryotic zinc-dependent phospholipase C signature. Length = 398 Score = 31.5 bits (71), Expect = 0.003 Identities = 15/69 (21%), Positives = 24/69 (34%), Gaps = 3/69 (4%) Query: 35 YEAFTETWKDSLSIGWQGNGAEALRSRTYADKVKVSDMVDQLHEAAKVARAGATDLSAAR 94 +E F E K+ I G YAD +K D E A+ + + Sbjct: 179 FETFAEERKEQYKINTAGCKTN---EDFYADILKNKDFNAWSKEYARGFAKTGKSIYYSH 235 Query: 95 SRMRNAVVD 103 + M ++ D Sbjct: 236 ASMSHSWDD 244
>PERTACTIN#Pertactin signature. Length = 922 Score = 33.2 bits (75), Expect = 1e-04 Identities = 18/45 (40%), Positives = 19/45 (42%) Query: 65 PPGPPPMWAAPPMPPPPLHGPPGPPHGFPPPPPGEAFPTLPPPSP 109 PP P P P P P PP PP PP P + P P P P Sbjct: 568 PPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQP 612 Score = 30.1 bits (67), Expect = 0.001 Identities = 20/56 (35%), Positives = 20/56 (35%) Query: 42 GAVGTVAAIAFAWIISVGPPGPPPPGPPPMWAAPPMPPPPLHGPPGPPHGFPPPPP 97 G V A A PGP P PP PP PP P P P P PP Sbjct: 558 GQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPP 613 Score = 26.6 bits (58), Expect = 0.023 Identities = 18/51 (35%), Positives = 19/51 (37%), Gaps = 5/51 (9%) Query: 60 PPGPPPPGPPPMWAAPPMPPPPLHGPPGPPHGFPPPPPGEAFPTLPPPSPR 110 P P PGP P PP PP PP PP P PP+ R Sbjct: 571 PKPAPQPGPQ-----PGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGR 616 Score = 26.2 bits (57), Expect = 0.036 Identities = 14/37 (37%), Positives = 14/37 (37%) Query: 74 APPMPPPPLHGPPGPPHGFPPPPPGEAFPTLPPPSPR 110 APP P P P P P PP P P P R Sbjct: 567 APPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQR 603
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.6 bits (199), Expect = 6e-20 Identities = 36/125 (28%), Positives = 66/125 (52%), Gaps = 1/125 (0%) Query: 2 LVVEDSETIREMVSEALTEVGYHTEARRDGERLEELLDGIRPDLVVLDVMLPGRDGFALI 61 LV +D IR ++++AL+ GY + L + DLVV DV++P + F L+ Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLL 66 Query: 62 DVIRDWG-DIGIVLITARDGLPDRLRGLDGGADDYVIKPFELAELVSRVGAVLRRRGRLP 120 I+ D+ +++++A++ ++ + GA DY+ KPF+L EL+ +G L R P Sbjct: 67 PRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRP 126 Query: 121 QVIQV 125 ++ Sbjct: 127 SKLED 131
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 38.8 bits (90), Expect = 2e-05 Identities = 14/36 (38%), Positives = 15/36 (41%) Query: 97 AEGPVEPPPPYPPPLPPPAYPPPYPPPYPPPPGPPP 132 +EPP PP P P P P P P PP P Sbjct: 51 TPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAP 86 Score = 37.3 bits (86), Expect = 8e-05 Identities = 10/39 (25%), Positives = 11/39 (28%) Query: 94 PDLAEGPVEPPPPYPPPLPPPAYPPPYPPPYPPPPGPPP 132 + P P P P P P P P P P Sbjct: 59 QAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK 97 Score = 36.1 bits (83), Expect = 2e-04 Identities = 15/51 (29%), Positives = 15/51 (29%), Gaps = 1/51 (1%) Query: 94 PDLAEGPVEPPPPYPPPLPPPAYPPPYPPPYP-PPPGPPPDTTATAVVHPL 143 P A P P P P P P PP P P P P V Sbjct: 57 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQ 107 Score = 36.1 bits (83), Expect = 2e-04 Identities = 16/49 (32%), Positives = 17/49 (34%), Gaps = 1/49 (2%) Query: 98 EGPVEPPPPYPPPLPPPAYPPPYPPPYP-PPPGPPPDTTATAVVHPLPD 145 PV P P P P+P P P P P P P P P D Sbjct: 65 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRD 113 Score = 36.1 bits (83), Expect = 2e-04 Identities = 12/41 (29%), Positives = 15/41 (36%) Query: 92 ISPDLAEGPVEPPPPYPPPLPPPAYPPPYPPPYPPPPGPPP 132 ++P E P PP P + P P P P P P Sbjct: 50 VTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIE 90 Score = 32.3 bits (73), Expect = 0.004 Identities = 14/54 (25%), Positives = 17/54 (31%) Query: 78 LVVTADGQAYGDRAISPDLAEGPVEPPPPYPPPLPPPAYPPPYPPPYPPPPGPP 131 +V AD + P+ P P P P P P P P P P Sbjct: 49 MVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP 102 Score = 31.9 bits (72), Expect = 0.004 Identities = 12/46 (26%), Positives = 13/46 (28%) Query: 98 EGPVEPPPPYPPPLPPPAYPPPYPPPYPPPPGPPPDTTATAVVHPL 143 E EP P P P P P P P V P+ Sbjct: 72 EPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPV 117
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 40.8 bits (95), Expect = 3e-06 Identities = 31/194 (15%), Positives = 62/194 (31%), Gaps = 17/194 (8%) Query: 36 TPAQQPTPPPVLAPIDLPAA---SAIGPGAGI-YVDYTDGSGGMGCTAGFLVHTSSGQAG 91 P +Q V+ P + + G A + Y+ +G + G +V G+ Sbjct: 59 KPLEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIAS-GVVV----GKDT 113 Query: 92 ILTAGHCNRP--GEPSKVTMNLGGVLPYATLGTFSQTISEGVHDEQHDIGLIILDGDNVP 149 +LT H G+P + + + + D+ ++ + Sbjct: 114 LLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQN 173 Query: 150 QSPAIAASVPVSGVAANLQVGQQLCKFGMGSGADAC------GQIVEITGSKVKFLAGGQ 203 + A QV Q + G G+I + G +++ Sbjct: 174 KHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTT 233 Query: 204 CGDSGGPVYRYEND 217 G+SG PV+ +N+ Sbjct: 234 GGNSGSPVFNEKNE 247
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 96.8 bits (241), Expect = 7e-25 Identities = 73/333 (21%), Positives = 122/333 (36%), Gaps = 48/333 (14%) Query: 3 RALITGITGQDGSYLAELLLSKGYEVHGLVRRASTFNTSRIDHLYVDPHQPGARL----- 57 + L+TG G G ++++ LL G++V G+ N Y D ARL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGI----DNLND------YYDVSLKQARLELLAQ 51 Query: 58 ---FLHYADLTDGTRLVTLLSSIDPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSIRLLE 114 H DL D + L +S + V+ + VR S + P D+ G + +LE Sbjct: 52 PGFQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILE 111 Query: 115 AVRLSRVDCRFYQASSSEMFGASP--PPQNESTPFYPRSPYGAAKVFSYWTTRNYREAYG 172 R +++ ASSS ++G + P + + +P S Y A K + Y YG Sbjct: 112 GCRHNKIQ-HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 173 LFAVNGILFNHESPRRGETFVTRKITRAVARIRAGVQSEVYMGNLDAIRDWGYAPEYVEG 232 L A F P K T+A + G +VY RD+ Y + E Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFTKA---MLEGKSIDVY-NYGKMKRDFTYIDDIAEA 226 Query: 233 MWRMLQAPEPDD-------------------YVLATGRGYTVREFAQAAFDHVGLDWQKH 273 + R+ D Y + + ++ QA D +G++ +K+ Sbjct: 227 IIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKN 286 Query: 274 VKFDDRYLRPTEVDSLVGDADRAAQSLGWKASV 306 L+P +V D + +G+ Sbjct: 287 --MLP--LQPGDVLETSADTKALYEVIGFTPET 315
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 72.9 bits (179), Expect = 1e-16 Identities = 60/287 (20%), Positives = 103/287 (35%), Gaps = 35/287 (12%) Query: 46 EIDLTDRAATFDFVSETRPQVIIDAAARVGGIMANNTYPADFLSENLRIQTNLLDAAVAV 105 +IDL DR D + + + + R + + P + NL N+L+ Sbjct: 58 KIDLADREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHN 116 Query: 106 RVPRLLFLGSSCIYPKYAPQPIHESALLTGPLEPTNDAYAIAKIAGILQVQAVRRQYGLA 165 ++ LL+ SS +Y P + P+ YA K A L YGL Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSL----YAATKKANELMAHTYSHLYGLP 172 Query: 166 WISAMPTNLYGP-GDNFSPSGSHLLPALIRRYEEAKAGGAEEVTNWGTGTPRRELLHVDD 224 +YGP G P + L + E K+ + + G +R+ ++DD Sbjct: 173 ATGLRFFTVYGPWGR---PDMA--LFKFTKAMLEGKS-----IDVYNYGKMKRDFTYIDD 222 Query: 225 LASACLFLLEHFDGPNH------------------VNVGTGVDHSISEIADMVATAVGYI 266 +A A + L + + N+G + + + A+G Sbjct: 223 IAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIE 282 Query: 267 GETRWDPTKPDGTPRKLLDVSALRE-LGWRPRIALKEGIDATVSWYR 312 + P +P D AL E +G+ P +K+G+ V+WYR Sbjct: 283 AKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYR 329
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 40.3 bits (94), Expect = 3e-06 Identities = 46/214 (21%), Positives = 81/214 (37%), Gaps = 11/214 (5%) Query: 21 RLLLRWRRDQ-AVLMGSLLLPIFLLFAYQIVLGERVHQVTGIGSVYGIAPMCAVISALFG 79 R + W++ A L+G L P+ LF LG V +V G+ +A SA+ Sbjct: 22 RNYIAWKKAALASLLGHLAEPLIYLFGLGAGLGVMVGRVGGVSYTAFLAAGMVATSAMTA 81 Query: 80 SLGNSVGITIDR--ESRVLSRMWVLPIHRASAVTGWVIAEVVRALIGTILITAIALAMGL 137 + ++ R R M + V G + +A + I +A A+G Sbjct: 82 ATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALG- 140 Query: 138 RFTNGWAAALLFLLIPSITVTGFTALVMAMAVRKKGRTAMTWLLSATFALA---FVNPGA 194 +T + L +P I +TG + M V + ++ T + F++ Sbjct: 141 -YTQWLS---LLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAV 196 Query: 195 TPIKLFPDWARPLIRMQPISPPIEAMRSLAHGGP 228 P+ P + R P+S I+ +R + G P Sbjct: 197 FPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHP 230
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.9 bits (64), Expect = 0.031 Identities = 20/127 (15%), Positives = 42/127 (33%), Gaps = 2/127 (1%) Query: 186 QVSPVRTAGMAPYMVRVLGTTAPT--QQVPQQAPLQQTPAQQAPLQQTPGQQAPLQQTPG 243 +++ V A + P T T + Q++ + Q A ++ + Sbjct: 1016 EIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSN 1075 Query: 244 QQLPTQQAPLQQVPGQQVPGQQLPTQQAPQQAPLQLAPTQQAPLQQLPTQQSPLQQLPVQ 303 + TQ + Q + Q T++ + A + Q++P S + Q Sbjct: 1076 VKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQ 1135 Query: 304 QSPLQPA 310 +QP Sbjct: 1136 SETVQPQ 1142
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 31.4 bits (71), Expect = 0.007 Identities = 14/72 (19%), Positives = 26/72 (36%), Gaps = 1/72 (1%) Query: 90 LADYVGAASGLLFSSGY-AANLGAVVGLSGRGALVVSDAYSHASLVDACRLSRARVVVTP 148 L G + Y A N G + GAL V ++++L D + V Sbjct: 404 LPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLY 463 Query: 149 HRDVDAVRAALQ 160 ++ ++ +Q Sbjct: 464 NKSLNESGTNIQ 475
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 29.7 bits (66), Expect = 0.028 Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 11/80 (13%) Query: 144 PERLARPRLSYPKRWGYRPAALGLFAFVWMELASPNPAAPSWVTGWLLIY----TVLMAA 199 +R A LS + PAA ++W + A W+ + Y Sbjct: 225 RDRSAMRYLSKVQYGNATPAA---DLYLW----TSATPAVQWLFTLVFDYGERGVDPQVP 277 Query: 200 GAWLCGQRWLARADPFGVYS 219 A+ WLAR DPF +Y+ Sbjct: 278 PAFTAQNSWLARQDPFSLYN 297
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 63.5 bits (154), Expect = 1e-14 Identities = 22/106 (20%), Positives = 44/106 (41%), Gaps = 10/106 (9%) Query: 7 PRRRRGRPAGSSGSRERILASARELFARNGIRNTSIRAVAAAAGVDSALVHHYFGTKEKL 66 R+ + + +R+ IL A LF++ G+ +TS+ +A AAGV ++ +F K L Sbjct: 2 ARKTKQE---AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDL 58 Query: 67 FAAAVQIPIDPMQVIGPLREVPVDDLGYALPSMLLPLWDSEVGAAF 112 F+ + + E+ ++ P L + + Sbjct: 59 FSEIWE------LSESNIGELELEYQA-KFPGDPLSVLREILIHVL 97
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 46.5 bits (110), Expect = 2e-08 Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 6/174 (3%) Query: 53 TMQRERASGTLERILTTPLRRLDLLIA--YGTAFSIAAAAQAILACTVSFWLLGFDTAGS 110 R T E +L T LR D+++ A A A I + LG+ S Sbjct: 90 AFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAA---LGYTQWLS 146 Query: 111 PVWVFVIAIVNAVLGVGLGLLCSAFARTEFQAVQFIPLVMVPQLLLAGIIVPRALMPHWL 170 ++ + + + LG++ +A A + + + LV+ P L L+G + P +P Sbjct: 147 LLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVF 206 Query: 171 QWISNVLPASYALEALQQVGTHPELTFIAVRDIVVVLGFALAALCLAAATLRRR 224 Q + LP S++++ ++ + + + + + + + L+ A LRRR Sbjct: 207 QTAARFLPLSHSIDLIRPIMLGHPVVDVCQH-VGALCIYIVIPFFLSTALLRRR 259
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 33.1 bits (75), Expect = 8e-04 Identities = 28/122 (22%), Positives = 48/122 (39%), Gaps = 7/122 (5%) Query: 20 VDHRDDAAVSDLFDRVRRESGRLDLLVNNAATISDNLVSSKPF--WEKPLDLADVLDVGL 77 D RD AA+ ++ R+ RE G +D+LVN A + L+ S WE + + V Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSV-NSTGVFN 122 Query: 78 RSSYVASWYAAPLLVAGGRGLIAFTSSPGSVCYMHGPAYGAQKAGVDKMAADMAVDFRGT 137 S V+ + ++ S+P V AY + KA + ++ Sbjct: 123 ASRSVSKYMMD----RRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY 178 Query: 138 GV 139 + Sbjct: 179 NI 180
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 103 bits (259), Expect = 7e-29 Identities = 73/268 (27%), Positives = 110/268 (41%), Gaps = 33/268 (12%) Query: 6 GRRAIVTGAGSGIGAATAARLLDEGATVVAYDISAEGLARTRAAADDAGTGKRLTTAVLD 65 G+ A +TGA GIG A A L +GA + A D + E L + ++ + D Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSS--LKAEARHAEAFPAD 65 Query: 66 ISVEGDVIAAVDGAVADLGGLEVLVNVAAIQTCSHTHQTTLADWNRTLAVNLTGTFLMTR 125 + + ++G +++LVNVA + H + +W T +VN TG F +R Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 126 QALPALLDSGRGVVVNFTSTAASFAHPYMAAYAASKGGILSFTHSLALEYAKQGLRAVNI 185 ++D G +V S A MAAYA+SK + FT L LE A+ +R + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 186 QPGGVSTALANSTLDKMPDGYDVGLWAKQTPLLHGKDSEILGD---------------PS 230 PG T + S LWA + +G + I G PS Sbjct: 186 SPGSTETDMQWS------------LWADE----NGAEQVIKGSLETFKTGIPLKKLAKPS 229 Query: 231 AVASVIAMVASDDGAFITGTEIRVDGGA 258 +A + + S IT + VDGGA Sbjct: 230 DIADAVLFLVSGQAGHITMHNLCVDGGA 257
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 57.8 bits (139), Expect = 5e-12 Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 6/165 (3%) Query: 3 VVLADIDGDAVAALRDELAAGGGAAHDAACDVRDPAAVQDLADR-AYDIGPVRLLVNNAG 61 + D + + + + L A A DVRD AA+ ++ R ++GP+ +LVN AG Sbjct: 35 IAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAG 94 Query: 62 IEQFGYLWDTPVVNWQHVMDVNVSGVFYGVRAFLPKMMAAGQQAWVWNIASVGAVVAMPL 121 + + G + W+ VN +GVF R+ MM + V + S A V Sbjct: 95 VLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYMMDRRSGSIV-TVGSNPAGVPRTS 153 Query: 122 QAPYIVSKHAVLALTECLHLEVQATGHDDHVHVQAVLPGPVRSNI 166 A Y SK A + T+CL LE+ + V PG +++ Sbjct: 154 MAAYASSKAAAVMFTKCLGLELAEYN----IRCNIVSPGSTETDM 194
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (256), Expect = 5e-28 Identities = 90/285 (31%), Positives = 129/285 (45%), Gaps = 33/285 (11%) Query: 4 VTGKVAVISGAARGQGRSHARMLAAEGADIIAVDLCADIETNEYPLARPEDLDETARLVE 63 + GK+A I+GAA+G G + AR LA++GA I AVD PE L++ ++ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVD------------YNPEKLEKVVSSLK 53 Query: 64 KEGQRAITAVADVRDRVALSAAIDAGVAEFGHLDIVVANAGIC--PLTAGLPPQAFADAV 121 E + A ADVRD A+ E G +DI+V AG+ L L + + Sbjct: 54 AEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATF 113 Query: 122 DVDLGGVLNLVHASLKHLRA--GASIIVIGSNAAFMSSLNTSGAGSGIGGPGGAGYAFAK 179 V+ GV N + K++ SI+ +GSN A G+ A YA +K Sbjct: 114 SVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPA------------GVPRTSMAAYASSK 161 Query: 180 LAAAHYVNDFALALAPFSIRMNAVHPTNVDTDMLHSPPMYRAFRPDLPAPTREDAEPVFP 239 AA + L LA ++IR N V P + +TDM S + + E + P Sbjct: 162 AAAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIP 221 Query: 240 LVQAMPVPYVEPEDISEAVLFLASDAARYITGQQLRVDAGGFLKV 284 L + +P DI++AVLFL S A +IT L VD G L V Sbjct: 222 LKK-----LAKPSDIADAVLFLVSGQAGHITMHNLCVDGGATLGV 261
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 109 bits (275), Expect = 2e-28 Identities = 48/272 (17%), Positives = 91/272 (33%), Gaps = 73/272 (26%) Query: 285 FSGVAPDVDIIAIRQSSQAFGLKDAYTGDEDPQTQAKIDNVQTMARAIVHAANMGASVIN 344 GVAP+ D++ I+ ++ + + I +A +I+ Sbjct: 103 VVGVAPEADLLIIKVLNKQGS-----------------GQYDWIIQGIYYAIEQKVDIIS 145 Query: 345 ISDVTCMSARNIIDQRALGAAVRYAAVDKNAVIVAAAGDTSKKDCKQNPPHDPLQPNDPR 404 MS D L AV+ A V +++ AAG N+ Sbjct: 146 ------MSLGGPEDVPELHEAVKKA-VASQILVMCAAG------------------NEGD 180 Query: 405 NWNSVTTVVTPSWFSDYVLTVGAVDTEGHPLSQGNQGQASTSVAGPWVGIAAPGTDVVGL 464 + + P + + V++VGA++ + H + S + V + APG D++ Sbjct: 181 GDDRTDELGYPGCY-NEVISVGAINFDRHA--------SEFSNSNNEVDLVAPGEDILS- 230 Query: 465 SPRDDGLINAIDGPDNTLLVPSGTSFSAAIVSGVAALVRAKYPQ-----LSAYQVINRLT 519 P SGTS + V+G AL++ L+ ++ +L Sbjct: 231 -----------TVPGGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLI 279 Query: 520 RTARAPARGVDNQVGHGIVDPVAA----LTWD 547 + G+G++ A +D Sbjct: 280 KRTIPLG-NSPKMEGNGLLYLTAVEELSRIFD 310 Score = 69.9 bits (171), Expect = 5e-15 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 7/94 (7%) Query: 77 TDFRLQPKYMDMLNLQEAWQFGRGAGQKVAVIDTGVTP-HPRFP-HLIPGGDYIMSGDG- 133 P+ ++M+ W RG G KVAV+DTG HP +I G ++ +G Sbjct: 17 QQVNEIPRGVEMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGD 76 Query: 134 ---LSDCDAHGTLVASMIGAASADGAGVPPAAPR 164 D + HGT VA I AA+ + GV AP Sbjct: 77 PEIFKDYNGHGTHVAGTI-AATENENGVVGVAPE 109
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.4 bits (66), Expect = 0.041 Identities = 28/143 (19%), Positives = 45/143 (31%), Gaps = 37/143 (25%) Query: 239 AVELLRRVYSRDPKFTPAREALDNPTYRLVLT---DPET-IEAR--------TDPWDPDS 286 A +LL R+ P LV++ T I+A P+D Sbjct: 62 AFDLLPRIKKARPD-----------LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTE 110 Query: 287 APTRAEAEAARHAEEAAKYLAEGDAELNAMLGMERAKREIKLIKSTTKVNLARAKMGLPV 346 A + L + + ++G A +EI + M + Sbjct: 111 L-IGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEI--------YRVLARLMQTDL 161 Query: 347 PVTSRHTLLLGPPGTGKTSVARA 369 + ++ G GTGK VARA Sbjct: 162 TL-----MITGESGTGKELVARA 179
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 146 bits (369), Expect = 6e-40 Identities = 94/426 (22%), Positives = 188/426 (44%), Gaps = 18/426 (4%) Query: 24 SPQRRNLIFVAIVLGMLLAALDQTIVATALPTIVANLGDAGHQ-SWVVTSYLLASTIVTA 82 S R N I + + + + L++ ++ +LP I + +WV T+++L +I TA Sbjct: 8 SNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTA 67 Query: 83 LVGKLGDLYGRKRVFQAAVLFFVAGSVLCGLAQSMA-MLVGARALQGIGGGGITVTASAL 141 + GKL D G KR+ ++ GSV+ + S +L+ AR +QG G + Sbjct: 68 VYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 142 IGEVVPLRERGRYQGILGAVFGVTTVIGPLLGGYFTDYLSWRWAFWVNVPVSVIVIFVAA 201 + +P RG+ G++G++ + +GP +GG Y+ W++ + +P+ I+ Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIH--WSYLLLIPMITIITVPFL 185 Query: 202 AAIPALAASAKPVIDYAGIVFVGLGAAGLTLATSWGGSRYPWGSPTITGLFAAAAVALGV 261 + K D GI+ + +G L T + Y ++ L + Sbjct: 186 MKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT----TSYSISFLIVSVLS------FLI 235 Query: 262 FVVVERRAAEPILPVRLFASPVFTVCCVLSFVVGFAMLGAMTFLPTYMQYVDGVSATTSG 321 FV R+ +P + L + F + + ++ + G ++ +P M+ V +S G Sbjct: 236 FVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIG 295 Query: 322 LRTL-PMVVGMLFTSTGSGTIVGRTGRYKIFPVAGTALMALAFLLMSRMQPSTPAVIQSL 380 + P + ++ G +V R G + + G ++++FL S + +T + + Sbjct: 296 SVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNI-GVTFLSVSFLTASFLLETTSWFMTII 354 Query: 381 YLFILGAGIGLSMQVLILIVQNTSDFEDLGVATSGVRFFRTIGSSFGAAIFGSLF-VNFL 439 +F+LG G+ + V+ IV ++ ++ G S + F + G AI G L + L Sbjct: 355 IVFVLG-GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLL 413 Query: 440 NRRIGP 445 ++R+ P Sbjct: 414 DQRLLP 419
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 66.6 bits (162), Expect = 5e-15 Identities = 52/190 (27%), Positives = 82/190 (43%), Gaps = 8/190 (4%) Query: 2 KSIFITGAGSGMGREGAKLFHAKGWRVGAVDRNDDGLATLQQELGDDRLWTRA--VDVTD 59 K FITGA G+G A+ ++G + AVD N + L + L + A DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 60 KAALDGALADFCAGNTGGGLDMMWNNAGIGESGWFEDVPYDAAMRVVDVNYKAVLTGAYG 119 AA+D A G +D++ N AG+ G + + VN V + Sbjct: 69 SAAIDEITARIER--EMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 120 ALPYLKKSAGSLMFSTSSSSATYGMPR--LAVYSSTKHAVKGLTEALSVEWQRHGVRVAD 177 Y+ + + S+ A G+PR +A Y+S+K A T+ L +E + +R Sbjct: 127 VSKYMMDRRSGSIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 178 VLPGLIDTAI 187 V PG +T + Sbjct: 185 VSPGSTETDM 194
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 33.2 bits (75), Expect = 6e-04 Identities = 16/39 (41%), Positives = 22/39 (56%) Query: 31 PDETHGPAPGPAATPSPAPSTSPSPAASPSPSASPAPAP 69 PD T G A P A P P S + +PA +P+P+ +P P Sbjct: 313 PDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRP 351 Score = 28.6 bits (63), Expect = 0.019 Identities = 13/48 (27%), Positives = 18/48 (37%) Query: 25 VVAGADPDETHGPAPGPAATPSPAPSTSPSPAASPSPSASPAPAPAAP 72 V +P P P P+P P +P A+P P P +P Sbjct: 331 VSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSP 378
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.3 bits (151), Expect = 4e-14 Identities = 28/169 (16%), Positives = 63/169 (37%), Gaps = 7/169 (4%) Query: 1 MADEQADSRERLISGTRELLWDRGYVGTSPTAILQQSGVGQGSLYHHFRGKHDLVLAAEQ 60 E ++R+ ++ L +G TS I + +GV +G++Y HF+ K DL + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 QAAADMQRSIKEAFAG-NRSAHDKIADYLTRQREVL-----RGCSVGRLTADPVIVGDDQ 114 + +++ E A + + L E R + + VG+ Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 115 LRAPVAQTFEV-LHTCLTRTIREGQRSGEISVELEPHKVAAAISATIQG 162 + + + + + +T++ + + +L + A + I G Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG 173
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 151 bits (384), Expect = 4e-43 Identities = 100/414 (24%), Positives = 170/414 (41%), Gaps = 24/414 (5%) Query: 10 LCLGTALIIMEANVLNVAIPSIRQALHASPAQSLWIIDAYTLVLAALLLSAGRLGDRIGA 69 LC+ + ++ VLNV++P I + PA + W+ A+ L + G+L D++G Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 70 RRCYLLGLAVFSIASVLCALAASSAE-LIAARTIQGVGAAVLIPAPLGLISAMFSDLTAR 128 +R L G+ + SV+ + S LI AR IQG GAA PA + ++ A + R Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAA-FPALVMVVVARYIPKENR 137 Query: 129 AKAVAVWVTIGGVGFAAGPLIGGLLVSTFGWRSIFLINIPAAAIIAV-MVRLTVAEASRS 187 KA + +I +G GP IGG++ W +L+ IP II V + + + R Sbjct: 138 GKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRI 195 Query: 188 PLPFDYVGQALAIVGLSAVVFACVESSALAWMSPFVLLPAVAAALILGLFVIDQRHRGRA 247 FD G L VG+ + S F+++ ++ +FV R Sbjct: 196 KGHFDIKGIILMSVGIVFFMLFTTSYSIS-----FLIVSVLS----FLIFVKHIRKVTDP 246 Query: 248 GAWVLLPVELLNNRPVNAGLMSGFVYNFTLYGLVLVYSYVFQSARGYSPVQTGLAFA-PL 306 + L N P G++ G + T+ G V + Y+ + S + G P Sbjct: 247 ----FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 307 TVAALVTSLPAGRFVAAHGARRGIMIGMALSAIGLCALAFDAQRMPFVVLSIAFGIFAT- 365 T++ ++ G V G + IG+ ++ +F + + + I Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWF---MTIIIVFVL 359 Query: 366 -GLSLSATGQTMAVMANASDQYKNTASSMLNTARQTGGVIGVAALGAITSRDLL 418 GLS + T + V ++ Q S+LN G+A +G + S LL Sbjct: 360 GGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLL 413
>cloacin#Cloacin signature. Length = 551 Score = 39.7 bits (92), Expect = 2e-06 Identities = 30/76 (39%), Positives = 32/76 (42%), Gaps = 6/76 (7%) Query: 68 GGPGGGGGSIPGGPTGGGGPGGGGGSIPGGPTGGGGPGGGGGSIPGGPTGGGGPGGGGGS 127 G G+I GGPTG G GGG G + GGG GS G G GGG Sbjct: 11 TGAHSTSGNINGGPTGL-GVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGN- 68 Query: 128 IPGVGGGGGGPGGGGG 143 G GGG G GG Sbjct: 69 ----GNSGGGSGTGGN 80 Score = 33.9 bits (77), Expect = 2e-04 Identities = 27/70 (38%), Positives = 30/70 (42%), Gaps = 4/70 (5%) Query: 85 GGPGGGGGSIPGGPTGGGGPGGGGGSIPGGPTGGGGPGGGGGSIP---GVGGGGGGPGGG 141 G G+I GGPTG G GGG G + GGG GS G G G G G G Sbjct: 11 TGAHSTSGNINGGPTGLG-VGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Query: 142 GGCVGNVCGG 151 G+ GG Sbjct: 70 NSGGGSGTGG 79 Score = 28.9 bits (64), Expect = 0.009 Identities = 30/79 (37%), Positives = 31/79 (39%), Gaps = 13/79 (16%) Query: 82 TGGGGPG-GGGGSIPGGPTGGGGPGGGGGS------------IPGGPTGGGGPGGGGGSI 128 +GG G G G G GG G G G P G G G GGGS Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 129 PGVGGGGGGPGGGGGCVGN 147 G GGG G GGG G GN Sbjct: 62 HGNGGGNGNSGGGSGTGGN 80
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 113 bits (283), Expect = 1e-32 Identities = 78/254 (30%), Positives = 112/254 (44%), Gaps = 26/254 (10%) Query: 4 RRVLITGASRGIGRAVADRLAEGGHEPIGLARSAPKD-----------FPGEFYEVDLAD 52 + ITGA++GIG AVA LA G + + K E + D+ D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 53 PYATAATLDKIVGHAA-VHAVVNNVGFARFGRLGSIELDHLFDTYNLNVRAAVQVVQAAL 111 A +I + +VN G R G + S+ + T+++N ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 112 PGMLDAEWGRIVNVTSLTTLGTPERT--PYAAAKAALEACTRIWAGELASAGITVNAVAP 169 M+D G IV V S G P + YA++KAA T+ ELA I N V+P Sbjct: 129 KYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 170 GPTETDMYR---------ERSPVGSAREARFLQSIPLHRVARPREIAHAICFLLDEDAGY 220 G TETDM E+ GS F IPL ++A+P +IA A+ FL+ AG+ Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSL--ETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 221 ITGQILRVDGGGSI 234 IT L VDGG ++ Sbjct: 246 ITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.0 bits (119), Expect = 7e-10 Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 1/98 (1%) Query: 1 MTNPRATNEDLTAKARIRNAALDLYAQYGEDRISLRDIASAAGVTLGLVQHHFKTKAGVR 60 M T + I + AL L++Q G SL +IA AAGVT G + HFK K+ + Sbjct: 1 MARKTKQEAQET-RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 61 DAVDQLVVDYFAHALAQVPAEGSARHVAAARDEAVARM 98 + +L + A+ ++ R+ + + Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVL 97
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 95.1 bits (236), Expect = 2e-25 Identities = 56/186 (30%), Positives = 83/186 (44%), Gaps = 1/186 (0%) Query: 6 KVVAITGGARGIGLATAKAFLAAGAKVALGDLDTELAEKQAVELGGDPAVV-GLSLDVSD 64 K+ ITG A+GIG A A+ + GA +A D + E EK L + DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 65 PASFVAFLDDVEARLGRLDVLVSNAGIMPTGPFVDEPPTMSRRMIDVNVYGVLNGSRLAA 124 A+ +E +G +D+LV+ AG++ G VN GV N SR + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 125 ARFVPRGAGHIVNIASLAGVTGEPGMATYCGTKHFVVGFTESLHRELRPHRVGVSLVLPG 184 + R +G IV + S MA Y +K V FT+ L EL + + ++V PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 185 IINTEL 190 T++ Sbjct: 189 STETDM 194
>PF07675#Cleaved Adhesin Length = 1358 Score = 29.3 bits (65), Expect = 0.007 Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 13/126 (10%) Query: 10 TTAATAALAAAGLLAAAPAFADP----QVLQFGQMAEISSNGGTIDYTVSNLQPSGHNDG 65 T A++ L +A PA ADP Q + E+ GG DY ++N +P+ + Sbjct: 427 TGTASSNLYSANFEYLTPANADPVVTTQNIIVTGQGEVVIPGGVYDYCITNPEPA--SGK 484 Query: 66 VWYSDVTAKGVSGNAVPNIADFNARAVNSSTFAVMKGNQTDGLPEGPLPLGTPVTGRLYF 125 +W G GN DF A TF + + DG + + +P Y Sbjct: 485 MW-----IAGDGGNQPARYDDFAFEAGKKYTFTMRRAGMGDGT-DMEVEDDSP-ASYTYT 537 Query: 126 DVRNGT 131 R+GT Sbjct: 538 VYRDGT 543
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 63.9 bits (155), Expect = 7e-15 Identities = 31/165 (18%), Positives = 63/165 (38%), Gaps = 12/165 (7%) Query: 4 VAQPVRSDAARNREALIEVATRLFAAAAGGDEPSLRLIAREAGVGVGTLFRHFPTREALV 63 +A+ + +A R+ +++VA RLF+ G SL IA+ AGV G ++ HF + L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQ-GVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 64 EAVYQDQVRRLTEGADQLLANHP--PAQAMRRWMDLFTDWLATKHGMLGTLRAMINNEQL 121 +++ + E + A P P +R + + T+ + + + + Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 122 GSGHTRI---------ELLAAIDKILAAGRAAGDIGDHISSEDVA 157 + E I++ L A + + + A Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAA 164
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 39.4 bits (92), Expect = 1e-05 Identities = 22/81 (27%), Positives = 30/81 (37%), Gaps = 11/81 (13%) Query: 35 VFVTGGSGLTGPAVVSELLSAGHRVTGLARSAASAD------RLARLGAEPFT---GSLD 85 VTG +G G V LL AGH+V G+ D RL L F L Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62 Query: 86 DLDRLREGAAAA--DGVIHMA 104 D + + + A+ + V Sbjct: 63 DREGMTDLFASGHFERVFISP 83
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 70.4 bits (172), Expect = 5e-17 Identities = 37/183 (20%), Positives = 63/183 (34%), Gaps = 7/183 (3%) Query: 19 LPRISREQKERNRGRILAAAGEGFKARGIDGVGIDELMKAAGMSHGGFYNHFPSKEDLAL 78 + R ++++ + R IL A F +G+ + E+ KAAG++ G Y HF K DL Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 79 EVLHQGFTDSLDTVAAVIDTHAHSGRAALHAIIDTYLSTEHRDHPEHGCASAALAADAGR 138 E+ ++ + + L I+ L + + + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRL-LMEIIFHKCEF 119 Query: 139 HGVKA--QEAYRRGLQGYIGAFADLLRVSARQRG---TKLDARRAREQAIGLFSQMVGAQ 193 G A Q+A R L+ + L RRA G S ++ Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLK-HCIEAKMLPADLMTRRAAIIMRGYISGLMENW 178 Query: 194 LIA 196 L A Sbjct: 179 LFA 181
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 73.9 bits (181), Expect = 1e-18 Identities = 33/175 (18%), Positives = 66/175 (37%), Gaps = 8/175 (4%) Query: 1 MTRTQQRAAENRRTVIDAAREIIATQGVEALTLEAVAEKADVVVQTIYNRVGGRSALLTA 60 +T+Q A E R+ ++D A + + QGV + +L +A+ A V IY +S L + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 61 VAEQALEQSRVYM-DPAYEADGTVEERMMLAANAYARFARERPHEFRILVEPPNEPEAVA 119 + E + + + G + ++ ++ E V Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 120 RIAELTRAQN-------ARLTAVLREGMAAGLIRADLDPDDVTTALWATFNGLLA 167 +A + +AQ R+ L+ + A ++ ADL + +GL+ Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLME 176
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 75.4 bits (185), Expect = 6e-19 Identities = 36/143 (25%), Positives = 70/143 (48%), Gaps = 3/143 (2%) Query: 14 RRKRADGEMSRERILDAATEIAAERGYEATSIGLVSAKCGLPASSIYWHFKNKDDLIAAV 73 R+ + + + +R+ ILD A + +++G +TS+G ++ G+ +IYWHFK+K DL + + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 74 IERSFADWRKAWQVPDEGAPRDRLAGLAMQIAKVLMDSP--DFIRLGLMLALERRPVEPR 131 E S ++ + P D L+ L +I +++S + R LM + + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLR-EILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 132 ARAMFIQARAQAYDELADIVREL 154 A+ QA+ E D + + Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQT 144
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 28.6 bits (64), Expect = 0.029 Identities = 17/59 (28%), Positives = 22/59 (37%), Gaps = 5/59 (8%) Query: 235 GLAPAWIGVGTLDLFYPECLEYARRLREAGVPAQEEIVPGAFHAFDQIVDKAPISAKFF 293 G+ W +G D F LE A LRE G ++ G FHA I + Sbjct: 42 GIERIWSAIGATDGFALLNLEEAITLRERGWKGPILMLEGFFHA-----QDLEIYDQHR 95
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.9 bits (129), Expect = 3e-11 Identities = 34/175 (19%), Positives = 61/175 (34%), Gaps = 9/175 (5%) Query: 1 MANPVGLRERRRRQTSADIRDAAVRLTLERGFDKVTVDEICAEAGISTRTFFNYFPNKES 60 MA + RQ I D A+RL ++G ++ EI AG++ + +F +K Sbjct: 1 MARKTKQEAQETRQH---ILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSD 57 Query: 61 ---AIAYGPSDIPPELVADFVAAGPAPYSVVLAELITLAAHHLRDVPPRREHAANMLELA 117 I EL ++ A P VL E++ + RR ++ Sbjct: 58 LFSEIWELSESNIGELELEYQAKFPGDPLSVLREIL-IHVLESTVTEERRRLLMEIIFHK 116 Query: 118 KTSPAVLAAFLADLERFQNQLTDIIVR--RQGMQPDDEMAPLISALALTAVRSGI 170 +A + D I + + ++ A L++ A +R I Sbjct: 117 CEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 45.2 bits (107), Expect = 1e-06 Identities = 46/253 (18%), Positives = 94/253 (37%), Gaps = 32/253 (12%) Query: 139 AQSNDGKASYVQVYLAGNQGEALANESVESVQNIVKSVQA--PNGVK---AYVTGP---A 190 A+ N A+ + + L A A ++ ++++ + +Q P G+K Y T P Sbjct: 279 ARINGKPAAGLGIKL---ATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQL 335 Query: 191 ALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLTLVMVVLELSAARGMVAFL 250 ++ T L A ++ + L +++ L+ + V + L ++A Sbjct: 336 SIHEVVKT-------LFEAIMLVFLV--MYLFLQNMRATLIPTIAVPVVLLGTFAILAAF 386 Query: 251 GYYKIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEARAVGES--REDAYYTMYKGTAH 308 GY I L+ F + LAI D AI ++ + + +E +M + Sbjct: 387 GY-SINTLTMFG----MVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGA 441 Query: 309 VVAGSGMTIAGATFCLHFTNL--PYFQTLGIPLAIGMVVVVAAALTLGPAVISVASRFRQ 366 +V + + A F ++ I + M + V AL L PA + + + Sbjct: 442 LVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPA---LCATLLK 498 Query: 367 TLEPRRTQRIRGW 379 + + G+ Sbjct: 499 PVSAEHHENKGGF 511 Score = 39.8 bits (93), Expect = 6e-05 Identities = 38/203 (18%), Positives = 75/203 (36%), Gaps = 18/203 (8%) Query: 740 KAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGISSLCLIFIIMLIITRGVV 799 KA L+ +G K+ + + LS ++ ++ L+F++M + + + Sbjct: 307 KAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHE---VVKTLFEAIMLVFLVMYLFLQNMR 363 Query: 800 ASAVIVGTVLLSLGASFGLSVLIWQHLIGIELHWMVL-AMSVIILLAVGADYNLLLV--- 855 A+ + V + L +F + G ++ + + M + I L V D +++V Sbjct: 364 ATLIPTIAVPVVLLGTFAI-----LAAFGYSINTLTMFGMVLAIGLLV--DDAIVVVENV 416 Query: 856 ARFKEEIHAGLNTGIIRSMGGTGSVVTSAGLVFAFT---MMTMAVSELTVIGQVGTTIGL 912 R E +SM + +V + M S + Q TI Sbjct: 417 ERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVS 476 Query: 913 GLLFDTLIVRSLMTPSIAALLGK 935 + L+ L TP++ A L K Sbjct: 477 AMALSVLVALIL-TPALCATLLK 498
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 64.4 bits (156), Expect = 3e-13 Identities = 69/261 (26%), Positives = 109/261 (41%), Gaps = 36/261 (13%) Query: 88 GRCPDVLMAWELSYAELADRGVLLDLGPLLARDKAFAQQLQADSIPALYETFTFNGKQYA 147 G PD++ + A G+L ++ P DKAF +L P ++ +NGK A Sbjct: 80 GDGPDIIFWAHDRFGGYAQSGLLAEITP----DKAFQDKL----YPFTWDAVRYNGKLIA 131 Query: 148 LPEQWSGNYLFYNKRLFDEAGVPSPPAAWEHPWGFSEFLNAARALTKRDASGRAAQYGFV 207 P L YNK L +P+PP WE + L A G++A Sbjct: 132 YPIAVEALSLIYNKDL-----LPNPPKTWEEIPALDKELKA---------KGKSAL--MF 175 Query: 208 NTWGSYYSAGLFAMNNG--VPWSDPRLNPTHFNFDNAAFQEAVQFYADL-ANKYRVAPNG 264 N Y++ L A + G + + + + DNA + + F DL NK+ A Sbjct: 176 NLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNA--- 232 Query: 265 SETQSMSTPNLFAVGRAAMALGGHWRYQTYLRAEGLDFDVAPLPVGPAVGKGQPACSDIG 324 +T F G AM + G W + ++ +++ V LP KGQP+ +G Sbjct: 233 -DTDYSIAEAAFNKGETAMTINGPWAWSNIDTSK-VNYGVTVLPTF----KGQPSKPFVG 286 Query: 325 ATGLAISSSSPRKEQAWEFVK 345 I+++SP KE A EF++ Sbjct: 287 VLSAGINAASPNKELAKEFLE 307
>cloacin#Cloacin signature. Length = 551 Score = 34.3 bits (78), Expect = 8e-04 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 11/72 (15%) Query: 212 AECGPIAY--PAVTKPPVGWITQDDGRVTLGAAVPLGLLSARVAEYLAALQAPLVITPWR 269 A P+A+ PA++ P G L ++ G LSA +A+ +AAL+ P W Sbjct: 83 AVAAPVAFGFPALSTPGAG---------GLAVSISAGALSAAIADIMAALKGPFKFGLWG 133 Query: 270 SVLVGDLREEVA 281 L G L ++A Sbjct: 134 VALYGVLPSQIA 145
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 37.0 bits (85), Expect = 2e-05 Identities = 37/171 (21%), Positives = 55/171 (32%) Query: 9 VLILGGRSEIGVELARRLAPGTTVVLAARNADRVNDQVDALKAAGASAVHTREFDADDLA 68 I G IG +AR LA + A ++V + A A D D A Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 69 SHGPLVASVVADHGPIGTAVLAFGILGDQARAETDAEHAVAIVHTDYVAQVSMLTHLAIA 128 + + A + + GPI V G+L E A + + ++ Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 129 MRAAGRGQLVVFSSIAGARVRRANYVYGSAKAGLDGFASGLADALHGTGVR 179 M G +V S R + Y S+KA F L L +R Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.0 bits (72), Expect = 0.002 Identities = 29/171 (16%), Positives = 52/171 (30%) Query: 2 KADVAQQRSLLELANVDAELSRLAHRAEHLPEQQACERMQQEYDAAGDRLGAVRIALEDI 61 +A A+ LE A + + + R A + I Sbjct: 189 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKI 248 Query: 62 DAHVLRLEAEVDAVRQREDRDRSLLQSGAIDAKQLADLQHELETLQRRQTSLEDSLLEVM 121 A + E + D+ ++ L+ E L+ + LE + Sbjct: 249 KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLN 308 Query: 122 ERREELQAQLDGEQQALKELEAEMATARRDLDAARGEISESRALHSSRRDA 172 R+ L+ LD ++A K+LEAE + R + R+A Sbjct: 309 ANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREA 359
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 42.7 bits (100), Expect = 2e-07 Identities = 31/178 (17%), Positives = 63/178 (35%), Gaps = 13/178 (7%) Query: 16 LEVGYTVLAEEGVRALKVERLCQQAGVTRGSFYWHFEDIDN-YRAALVESWNKFLERDRQ 74 L+V + +++GV + + + + AGVTRG+ YWHF+D + + S + E + + Sbjct: 17 LDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELE 76 Query: 75 ALSELDSLPPRQRLSAMMGTLVSPQYWMLERAMR-----------EWARLDPVAAENIRA 123 ++ P ++ L S R + E A + Sbjct: 77 YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLE 136 Query: 124 ADRHLLRTVTKAYRDYGF-SPEDAKLRAELTFAAGIGLLHLTGSAEQAQSLAQRERFL 180 + + +T+ + + A + GL+ A Q+ L + R Sbjct: 137 SYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDY 194
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 29.7 bits (66), Expect = 0.036 Identities = 31/138 (22%), Positives = 54/138 (39%), Gaps = 12/138 (8%) Query: 95 QTLHEMLKTGSLEPRRATDIIRQVASAL----DAAHAAGLIHRDVKPQNIIVT-PDDFAY 149 +TL + K G + I+ +A L + AG++H D+KP N++ Sbjct: 227 RTLADSWKQGKINSEAYWGTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPV 286 Query: 150 LVDFGIAEARGDTHLTMAGHTVGTFDYMAPER-FGDEETTSAVDVYALACVLYEALTGAK 208 ++D G+ G+ T + APE G+ + DV+ + L + G + Sbjct: 287 VIDLGLHSRSGEQPKGF------TESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEGFE 340 Query: 209 PFPVHSAEQAIRAHLSSP 226 P Q +R S P Sbjct: 341 KNPEIKPNQGLRFITSEP 358
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.0 bits (62), Expect = 0.044 Identities = 24/106 (22%), Positives = 46/106 (43%), Gaps = 2/106 (1%) Query: 24 AGVLGANDGIVSTAGIVVGVAAATALRAPILTAG-SAGLVAGAVSMALGEYVSVSTQRDT 82 AGV + + + A + T+ +AGL+A AV++A+ +S Sbjct: 271 AGVELTTKVLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASAVTLAISPLSFLSIADKF 330 Query: 83 EKALLIQEHQELRDDPAAELDE-LAALYEAKGLTAATARTVAEELT 127 ++A I+E+ + + D LAA ++ G A+ T++ L Sbjct: 331 KRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASLTTISTVLA 376
>PF06580#Sensor histidine kinase Length = 349 Score = 40.2 bits (94), Expect = 3e-05 Identities = 19/86 (22%), Positives = 29/86 (33%), Gaps = 14/86 (16%) Query: 811 VANAIEHGHRHSPQ-GTIRLGATALGDQVRLTITDTGTWKVPQATSYPHRGRGIPL---- 865 V N I+HG PQ G I L T V L + +TG+ + G L Sbjct: 264 VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT----KESTGTGLQNVR 319 Query: 866 --MKSLMND---VDIRSDTGGTTVQL 886 ++ L + + G + Sbjct: 320 ERLQMLYGTEAQIKLSEKQGKVNAMV 345
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 36.1 bits (83), Expect = 2e-04 Identities = 26/98 (26%), Positives = 33/98 (33%), Gaps = 6/98 (6%) Query: 71 PPSNAPTRPPEVPVPAYEPPPIP-VPVQSPLVLPPPNAGQGAVPVLEINPPGPDAPRDAP 129 PP P V P EP PIP P ++P+V+ P P P Sbjct: 57 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKP 116 Query: 130 VVAPPRGLDAPSLAIAAAKAAPVTRVDPANPPKPPTQV 167 V + P +P A A+ T KP T V Sbjct: 117 VESRP---ASPFENTAPARLTSSTATAA--TSKPVTSV 149 Score = 31.9 bits (72), Expect = 0.004 Identities = 21/93 (22%), Positives = 28/93 (30%), Gaps = 5/93 (5%) Query: 75 APTRPPEVPVPAYEPPPIPVPVQSPLVLPPPNAGQGAVPVLEINPPGPDAPRDAPVVAPP 134 A PP+ P EP P P P+ PP PV+ P P+ PV Sbjct: 53 ADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKE-----APVVIEKPKPKPKPKPKPVKKVQ 107 Query: 135 RGLDAPSLAIAAAKAAPVTRVDPANPPKPPTQV 167 + + A+P PA Sbjct: 108 EQPKRDVKPVESRPASPFENTAPARLTSSTATA 140 Score = 30.3 bits (68), Expect = 0.012 Identities = 17/100 (17%), Positives = 28/100 (28%), Gaps = 5/100 (5%) Query: 68 VQGPPSNAPTRPPEVPVPAYEPPPIPVPVQSPLVLPPPNAGQGAVPVLEINPPGPDAPRD 127 P P PE P A P P P P + ++ P +P + Sbjct: 67 PVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFE 126 Query: 128 ----APVVAPPRGLDAPSLAIAAAKA-APVTRVDPANPPK 162 A + + + A ++R P P + Sbjct: 127 NTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPAR 166
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 78.9 bits (194), Expect = 4e-20 Identities = 39/203 (19%), Positives = 81/203 (39%), Gaps = 5/203 (2%) Query: 24 QRSRERIANQVRLMLDAALRLIREKG-DSFTTQELVKEAGVALQTFYRYFATKDELLLAV 82 +++++ + +LD ALRL ++G S + E+ K AGV Y +F K +L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 83 IADAMTDACARWRDAARDLP-DPVARLRFYVTAVIEVLDNEQGDGGTAKFVVSTHWRLHR 141 + ++ + P DP++ LR + V+E E+ + + + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 142 VFPDELAEAEKPF--VDLLLGEINAGIEAG-LLAPADPKWAAWFIAELVRSVYHYYAYAP 198 + + A+ D + + IEA L A + AA + + + + +AP Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 199 REVDVKEQLWQFCLTALGGTARK 221 + D+K++ + L Sbjct: 183 QSFDLKKEARDYVAILLEMYLLC 205
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 104 bits (261), Expect = 4e-29 Identities = 67/255 (26%), Positives = 118/255 (46%), Gaps = 6/255 (2%) Query: 5 LAGKSAIVTGAGSGVGRVSALRFAEEGARVVAADIDLDHAKETVCQIESAGGTAIAIGTD 64 + GK A +TGA G+G A A +GA + A D + + ++ V +++ A A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 65 VSDEQQVQAMIAAAVDQYGRLDILFNNVGIPTPRLGMIFEDHTLEDFNRLVAVNLGGVFL 124 V D + + A + G +DIL N G+ R G+I + E++ +VN GVF Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGV--LRPGLIHS-LSDEEWEATFSVNSTGVFN 122 Query: 125 GCKYAVLRFKEQGAGGVILNTASVAGLVGWGGSVYGATKGGVIQLTRAVAIEAAPFGIRV 184 + ++ +G ++ ++ AG+ + Y ++K + T+ + +E A + IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 185 NAICPAAMPLTGFMAAGGLEVDAEQQ--AAIAESVGGQHPLGRAITAEDCAEAALYLVSD 242 N + P + T + + + +Q E+ PL + D A+A L+LVS Sbjct: 183 NIVSPGSTE-TDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 243 AARNVTGVALPVDGG 257 A ++T L VDGG Sbjct: 242 QAGHITMHNLCVDGG 256
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 30.5 bits (68), Expect = 0.011 Identities = 17/73 (23%), Positives = 23/73 (31%), Gaps = 5/73 (6%) Query: 56 QRRQDAGQARSRRR-----RGLGETRCGGARKRGGRRRTDQPAGFDARGAQSPAGPTAAG 110 Q R + A E A+++ + Q A A PA + Sbjct: 201 QIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYAMPANGSVVA 260 Query: 111 TAAARGHHPAGQG 123 TAA RG QG Sbjct: 261 TAAGRGLIQVAQG 273
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 62.0 bits (150), Expect = 2e-13 Identities = 53/212 (25%), Positives = 87/212 (41%), Gaps = 10/212 (4%) Query: 9 SKTSRGALAVVTGAGSGIGAAFALELGKRGGTVVCSDIDQAAAQRTADAITQHGAKALAT 68 +K G +A +TGA GIG A A L +G + D + ++ ++ A A Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 69 RCDVSQFGDVQALAEQSQSCFG--APPTLVINNAGVGAGGAAIGDAPLDDWQWTLGINLW 126 DV D A+ E + P +++N AGV G I ++W+ T +N Sbjct: 63 PADVR---DSAAIDEITARIEREMGPIDILVNVAGVLRPGL-IHSLSDEEWEATFSVNST 118 Query: 127 GPIHGCHVFTPILRDAAPSAAPRGIINVASAAAFGAAPGMAAYNVSKAGVLSLSETLAAE 186 G + + + D + I+ V S A MAAY SKA + ++ L E Sbjct: 119 GVFNASRSVSKYMMDRRSGS----IVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLE 174 Query: 187 LSGTPVRVTVLCPTFVKTNILESGRISEESGE 218 L+ +R ++ P +T++ S E E Sbjct: 175 LAEYNIRCNIVSPGSTETDMQWSLWADENGAE 206
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 29.1 bits (65), Expect = 0.023 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 10/67 (14%) Query: 161 FEKINNDESRHLVVDFEVLDMIGHAKVRRLLIDFVGHHA-------TPGLIIGAITG-AP 212 +IN D R +V+DFE D +G + L+I+ +G H+ +I+ +I P Sbjct: 91 IHQINQD--RIVVIDFESTDELGFNSIYSLIIEIMGRHSNMTLIRKRDNIIMDSIKHITP 148 Query: 213 LINRIRN 219 IN R+ Sbjct: 149 DINTYRS 155
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 41.8 bits (98), Expect = 4e-06 Identities = 67/421 (15%), Positives = 134/421 (31%), Gaps = 58/421 (13%) Query: 48 LPALSAHYRIGPATAALTVSLTTGALALSIIPASVLSERYGRIRVMLISGVASSVIGLLL 107 LP ++ + PA+ + ++ LS++ G R++L + + ++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 108 PFSPS-LGVLLFGRAAQGVALAGIPAVAMALLAEEVDASSLGSAMGRYIAGTTIGGLAGR 166 S +L+ R QG A PA+ M ++A + + G A G + +G G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 167 IVPSVVVQVGTWRVALLACSLITLAGTAVFAVLVPRSR------------FFTPKPASVR 214 + ++ W LL + + + +L R + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFML 216 Query: 215 AALRNLAGHL---------------------------RNPVLAKLFAVGFVLMGGFVTVY 247 L +N G ++ G Sbjct: 217 FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV 276 Query: 248 NYLGYRLAARPFGLAPSVVGLLFLL--YLVGTGTSVVAGRLADRRGRPLVLGAALPIAVA 305 + + Y + L+ + +G + + + + G L DRRG VL + Sbjct: 277 SMVPYMM-KDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV 335 Query: 306 GLL---LTVPATLAAIVAGVGVFTGGFFAAHTVASGWV-GAVAQRDRAEASALYLFSYYL 361 L + T + + GG TV S V ++ Q++ +L F+ +L Sbjct: 336 SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFL 395 Query: 362 GGSVAGAFGGVLYGVG-----------GWSATVCFVVVLLMAGAALVALLVRDNGFRIGR 410 A G L + S + ++LL +G +++ LV N ++ + Sbjct: 396 SEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVYKHSQ 455 Query: 411 R 411 R Sbjct: 456 R 456
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 127 bits (321), Expect = 4e-38 Identities = 79/251 (31%), Positives = 123/251 (49%), Gaps = 6/251 (2%) Query: 3 RVAVVTGGGSGIGRAIVERLAHDRHRVAVLDVNEEAAEKVAARVAADGAHAIAVPTDVAE 62 ++A +TG GIG A+ LA +A +D N E EKV + + A+ HA A P DV + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 63 SASVAAAFESVRRALGPVQVLVTSAAITGFKPFGEITIEDWNRHLAVNLTGTFLCLQAAL 122 SA++ + R +GP+ +LV A + ++ E+W +VN TG F ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 123 PDMVEAGWGRVVTISSTAAQTGSPRQGHYSASKGGVIALTRTIALEYAVHGITANTVPPF 182 M++ G +VT+ S A Y++SK + T+ + LE A + I N V P Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 183 SVDTPMLRA--AQEAGNLPPVKYLAK----ASPVGRLGTGEDIAAACAFLCSDEAGYITG 236 S +T M + A E G +K + P+ +L DIA A FL S +AG+IT Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 237 QIIGVNGGAVI 247 + V+GGA + Sbjct: 249 HNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.3 bits (151), Expect = 4e-14 Identities = 20/88 (22%), Positives = 37/88 (42%) Query: 7 PRRVGAETSQTRDALLEAVAQMMLEEGYASVTYRALAAKAGVTPSLVQYYFPSLDDIFVA 66 R+ E +TR +L+ ++ ++G +S + +A AGVT + ++F D+F Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 67 AIRRYSERNLQWLTEELQRRADDPLHAL 94 + E + DPL L Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVL 89
>PF07472#Fucose-binding lectin II Length = 245 Score = 28.5 bits (63), Expect = 0.027 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 133 TWGGVDPALPEVAAEFGAGLVCSHTGNALPRTRPFRVSYGTSTRG 177 TW G LP AA+FG G V ++ A P+ P GT+T G Sbjct: 87 TWAGAPGVLPGAAAKFGVGAVVNYFSKATPQPEP--TQPGTTTGG 129
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 36.5 bits (84), Expect = 2e-05 Identities = 14/46 (30%), Positives = 16/46 (34%) Query: 122 APPPPDAPPPPPDAPAPPPDAPPAPPEAPAVLIDAPAPVPPPPPGP 167 PP PPP P P+ P P + P P P P P Sbjct: 55 LEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP 100 Score = 31.9 bits (72), Expect = 8e-04 Identities = 18/61 (29%), Positives = 22/61 (36%), Gaps = 5/61 (8%) Query: 107 FTHHMFLPMPPEDGGAPPPPDAPPPPPDAPAPPPDAPPAPPEAPAVLIDAPAPVPPPPPG 166 T + P PPP P P+ P AP V+I+ P P P P P Sbjct: 47 VTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAP-----VVIEKPKPKPKPKPK 101 Query: 167 P 167 P Sbjct: 102 P 102 Score = 26.9 bits (59), Expect = 0.038 Identities = 9/39 (23%), Positives = 9/39 (23%) Query: 114 PMPPEDGGAPPPPDAPPPPPDAPAPPPDAPPAPPEAPAV 152 E P P PP P P P P Sbjct: 66 EPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 104
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.7 bits (69), Expect = 0.005 Identities = 18/75 (24%), Positives = 24/75 (32%), Gaps = 8/75 (10%) Query: 100 PTAARPVTIEPA--AALPTVTAVQAPAAA------PPATVTVTPPPAPPATVTVQAAPAP 151 P A+P+++ A L AVQ P P + P AP + P P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 103 Query: 152 APTVVKPAPALPPPG 166 P VK Sbjct: 104 KPKPVKKVEQPKRDV 118
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 37.7 bits (87), Expect = 4e-04 Identities = 42/185 (22%), Positives = 66/185 (35%), Gaps = 6/185 (3%) Query: 40 GLGGSLSKAFAAVDGTA----ARRDLLALQQEWRRAADVEADAAARMIRDQRRLAEATVK 95 G GGS S++ AA+ TA A+ +Q R A EA A A+ RD L + Sbjct: 39 GKGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDA--LTQRLKD 96 Query: 96 YGDDSSRTAAAQAMLARSQRDHIDAMIAAEAAHGRLAKAGNETADSVSRMQKLGANPIFN 155 +++ R A++ A +A + AE RLAKA + +K Sbjct: 97 IVNEALRHNASRTPSATELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQR 156 Query: 156 AAGIGSVAAMGIGLVSATDAAGNFQQSLQRLHTVAEESPANLKAISDGVLKLSSVVGYAP 215 I A + +A +L E + L A V+K+ + Sbjct: 157 RKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLN 216 Query: 216 QKLMD 220 +L Sbjct: 217 SRLSS 221
>PERTACTIN#Pertactin signature. Length = 922 Score = 27.4 bits (60), Expect = 0.030 Identities = 17/59 (28%), Positives = 22/59 (37%) Query: 17 PTRQTPAARRRSGPAPHPTARPTQKATPHPPQPERHTMTTDNPTPSDDQALAALYATAL 75 P PA + P P P P P PPQP + P P + L+A A+ Sbjct: 568 PPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRELSAAANAAV 626
>PERTACTIN#Pertactin signature. Length = 922 Score = 29.3 bits (65), Expect = 0.035 Identities = 16/37 (43%), Positives = 19/37 (51%) Query: 35 ARPAPRPGPRPGPRPVSAGRPAAHPVVVPPPPSDPHR 71 A PAP+P P+PGP+P P P PP P R Sbjct: 567 APPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQR 603
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.8 bits (67), Expect = 0.035 Identities = 27/106 (25%), Positives = 39/106 (36%), Gaps = 23/106 (21%) Query: 150 AQVEIAEALQQFPSSLPSARESAYAAWVSISVGCNNSCTFCIVPSLRGKEVDRSPDDILA 209 AQV++ LQ LP + ISV +S ++ +V + DDI Sbjct: 103 AQVQVQNKLQLATPLLPQEVQQ-----QGISVE-KSSSSYLMVAGFVSDNPGTTQDDISD 156 Query: 210 EVRSLVAD------GVLEVTLLG-----------QNVNAYGVSFAD 238 V S V D GV +V L G +N Y ++ D Sbjct: 157 YVASNVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVD 202
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 33.5 bits (76), Expect = 4e-04 Identities = 12/22 (54%), Positives = 13/22 (59%) Query: 196 RASCCLFYRLPGGSVCGDCVLD 217 R +CC YRLP CGDC L Sbjct: 241 RRTCCQRYRLPDVQQCGDCTLK 262
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.3 bits (65), Expect = 0.006 Identities = 16/84 (19%), Positives = 26/84 (30%), Gaps = 4/84 (4%) Query: 69 RRNGSMAEENKSGPAEAVKGVVEDVKGKAKEAVGAVAGRDDLTREGQAQQDKAEAQRDAA 128 ++ E+N+ E + AKEA V Q+ + E Q Sbjct: 1045 KQESKTVEKNEQDATETTA----QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTET 1100 Query: 129 KKEAEAEAARGGAEAAEERQRANQ 152 K+ A E E+ Q + Sbjct: 1101 KETATVEKEEKAKVETEKTQEVPK 1124
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 120 bits (301), Expect = 9e-35 Identities = 76/251 (30%), Positives = 118/251 (47%), Gaps = 13/251 (5%) Query: 36 GKKAIITGGDSGIGRAVAIAYAREGADVLIAYLNEDDDARDVARHVTDAGRKCVLVPGDL 95 GK A ITG GIG AVA A +GA + N + + V + R P D+ Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEK-VVSSLKAEARHAEAFPADV 66 Query: 96 SDPAHCRAVVDRAVRELGGVDILVNNAAYQMMHKNLDEISDEEWDYTFRLNVGAYFYLTK 155 D A + R RE+G +DILVN A + +SDEEW+ TF +N F ++ Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGL-IHSLSDEEWEATFSVNSTGVFNASR 125 Query: 156 AALPHLRA--GSSIIGSSSVNSDTPNPTLAPYAATKAAIANFSASLAQLLGDKGIRVNSV 213 + ++ SI+ S + P ++A YA++KAA F+ L L + IR N V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 214 APGPIWTPLIPSTMPPD---------SVESFGDNVPLGRAGQPAELAPIYVLLASDEASY 264 +PG T + S + S+E+F +PL + +P+++A + L S +A + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 265 ISGARVAVTGG 275 I+ + V GG Sbjct: 246 ITMHNLCVDGG 256
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 29.1 bits (64), Expect = 0.009 Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 17 PAAAGDLHLEWPLRPPPVVVRAFEAPAQDWHPGHRGVDLAGTAGQPVYAAGAGTV 71 P A L LE+P+RPP A A+ H G G V A GAG++ Sbjct: 41 PNADPALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAV-AVGAGSI 94
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 32.2 bits (73), Expect = 0.006 Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 24/167 (14%) Query: 248 NAGSATSSNGAAGSTFMTTTIATAT-AMLAWMLTERIRDGKATTLGAASGIVAGLVAITP 306 NA + T + AAG T + + +++ +R G +T+ AA+G++A V + Sbjct: 260 NADADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLSTS-AAAAGLIASAVTL-- 316 Query: 307 SCSSVNVLGALVVGLVAGVVCALAVGLKFKLGFD-DSL-------------DVVGVHLV- 351 + S ++ L A + + K KLG+D DSL + + V Sbjct: 317 AISPLSFLSIADKFKRANKIEEYSQRFK-KLGYDGDSLLAAFHKETGAIDASLTTISTVL 375 Query: 352 ----GGLAGTLLVGLLAAPESPAISGVTGVSKGLFYGGGWAQLERQA 394 G++ L+ AP S + VTG+ G+ A E A Sbjct: 376 ASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVA 422
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 36.6 bits (84), Expect = 2e-04 Identities = 32/194 (16%), Positives = 71/194 (36%), Gaps = 20/194 (10%) Query: 95 TISEVELPEPETPAAPAAEAPAPEAPESPEAPAPEAPAPE-IEEIAPTEGRLERLRGRLA 153 T + ++ P P+ A EAP P APA + E + E + E + + Sbjct: 999 TPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQ-- 1056 Query: 154 RSQNALGRSLLGLIGGGDLDEDAWQDVEDTLLVADLGPVVTESVIAQLRGRLASSDVRTE 213 + ++ ++ ++A +V+ ++ +E+ Q ++ V E Sbjct: 1057 DATETTAQN-------REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 214 ADAKAVLRDV-----LINELRPDLDRSIRALPHAD-----HPSVLLIVGVNGTGKTTTVG 263 AK + +++ P ++S P A+ P+V + + T T Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTE 1169 Query: 264 KLARVLVADGRRVV 277 + A+ ++ + V Sbjct: 1170 QPAKETSSNVEQPV 1183
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 43.1 bits (101), Expect = 6e-06 Identities = 37/231 (16%), Positives = 81/231 (35%), Gaps = 1/231 (0%) Query: 306 SDELAAHEKALGELSGRAESVQQTWFALSALAERVAATVRIASERAQHLDLEPVTTGDTD 365 D + L + ++ ++ + + A + E+A + T Sbjct: 84 KDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEAR-KADLEKALEGAMNFSTADSAK 142 Query: 366 PDALEAEAERVAAAEQQLLAELATARSRLETARAELAEREREAAEADRAHMAAVRAEADR 425 LEAE +AA + L L A + A++ E E A + +A Sbjct: 143 IKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA 202 Query: 426 REGLARLAGQVETMRARVESIDDSVARLSERIEAAAARAQQAKAEFETVQGRVGELDQGE 485 + +++T+ A ++ A L + +E A + A+ +T++ L+ + Sbjct: 203 MNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQ 262 Query: 486 VGLDEHHERTVAALRLADERVAELQAAERDAERKVASLRARIDALAVGLER 536 L++ E + ++ L+A + E + A L + L + Sbjct: 263 AELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQS 313 Score = 36.2 bits (83), Expect = 8e-04 Identities = 60/320 (18%), Positives = 112/320 (35%), Gaps = 19/320 (5%) Query: 210 HRKRKEKALRKLDAMSANLARLTDLTTELRRQLKPLGRQAEVARRAQTIQADLRDARLRL 269 K+ + A A L +L + L+ A A+ + A L Sbjct: 132 AMNFSTADSAKIKTLEAEKAALAARKADLEKALEGA-MNFSTADSAKIKTLEAEKAALEA 190 Query: 270 AADDLVNRRGEREAIFEAEAAMRREHDEASARLAVASDELAAHEKALGELSGRAESVQQT 329 +L A++A + + A LA +L + S + +T Sbjct: 191 RQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKT 250 Query: 330 WFALSALAERVAATVRIASERAQHLDLEPVTTGDT---DPDALEAEAERVAAAEQQLLAE 386 A A E A + A E A + T + ALEAE + Q L A Sbjct: 251 LEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNAN 310 Query: 387 LATARSRLETARAELAEREREAAEADRAHMAAVRAEADRREGL-------ARLAGQVETM 439 + R L+ +R + E E + + + + + R L +L + + + Sbjct: 311 RQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKL 370 Query: 440 RARVESIDDSVARLSERIEAAAARAQQAKAEFETVQGRVGELDQGEVGLDEHHERTVAAL 499 + + + S L ++A+ +Q + E ++ L++ L+E + Sbjct: 371 EEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEE-------SK 423 Query: 500 RLADERVAELQAAERDAERK 519 +L ++ AELQ A+ +AE K Sbjct: 424 KLTEKEKAELQ-AKLEAEAK 442 Score = 35.8 bits (82), Expect = 0.001 Identities = 50/381 (13%), Positives = 102/381 (26%), Gaps = 54/381 (14%) Query: 702 KAGAELAAAEAQVAQLSAALSGALAEQAARQDSAEQALAALNESDSAISGMYEQLGRLGQ 761 + + + ++ E + + E+L + Sbjct: 40 VSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKE 99 Query: 762 EARTSEDEWSRLLRQREELEAGRTQTVAEVTELENRLRNAQETPQEPAAEPVNRQQIAAA 821 + R ++ S + +ELEA + + N + AE A Sbjct: 100 KLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKAD 159 Query: 822 TDAARSAEVEARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQAREARLRAAAVA 881 + A + A + A + ++ + E + A A+++ Sbjct: 160 LEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEA- 218 Query: 882 AAVADSGRLLATRLNAVVAAASRIRDALAAERQQRATAMAAVRDEVNALSARVAALTDSL 941 L A A + + + + + E AL AR A L +L Sbjct: 219 ---------EKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKAL 269 Query: 942 HSDEVANAQAALRIEQLEQMVLEQFGMAPADLIAEYGPHIALPPSELEMAEYEQAKERGE 1001 + + +I+ LE AE + Sbjct: 270 EGAMNFSTADSAKIKTLE-------------------------------AEKAALEAEKA 298 Query: 1002 QVFAPAPIPFDRPTQERRAKRAERELAELGRVNPLALEEFAALEERYNFLSTQLEDVKAA 1061 + + + A R+ L R + E LE + L Q + +A+ Sbjct: 299 DL-----------EHQSQVLNANRQ--SLRRDLDASREAKKQLEAEHQKLEEQNKISEAS 345 Query: 1062 RKDLLGVVDEVDARILQVFSE 1082 R+ L +D Q+ +E Sbjct: 346 RQSLRRDLDASREAKKQLEAE 366 Score = 32.3 bits (73), Expect = 0.014 Identities = 32/170 (18%), Positives = 63/170 (37%), Gaps = 10/170 (5%) Query: 695 EVTSEIDKAGAELAAAEAQVAQLSAALSGALAEQAARQDSAEQALAALNESDSAISGMYE 754 + A++ EA+ A L+A + + + A + ++ + + Sbjct: 201 GAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEA 260 Query: 755 QLGRLGQEARTSEDEWSRLLRQREELEAGRTQTVAEVTELENRLRNAQETPQEPAAEPVN 814 + L + + + + + + LEA + AE +LE+ + N Sbjct: 261 RQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEH----------QSQVLNAN 310 Query: 815 RQQIAAATDAARSAEVEARLAVRTAEERANAVRGRADSLRRAAAAEREAR 864 RQ + DA+R A+ + + EE+ SLRR A REA+ Sbjct: 311 RQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAK 360
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 54.2 bits (130), Expect = 2e-10 Identities = 61/274 (22%), Positives = 93/274 (33%), Gaps = 36/274 (13%) Query: 91 SADPQRIVVLAGDQLDALCALGLQSRVVGAALPDGASGQPAYLGGAV-----RGVPGVGS 145 + DP RIV L ++ L ALG+ P G + Y V VG Sbjct: 32 AIDPNRIVALEWLPVELLLALGIV--------PYGVADTINYRLWVSEPPLPDSVIDVGL 83 Query: 146 RSHPDVKAIAAAHPDLILGSQGLTPALYPQLAAIAPT-VFTAA----PGAAWRDNLRAVG 200 R+ P+++ + P ++ S G P+ LA IAP F + P A R +L + Sbjct: 84 RTEPNLELLTEMKPSFMVWSAGYGPS-PEMLARIAPGRGFNFSDGKQPLAMARKSLTEMA 142 Query: 201 AATARAGAVDGLLS---GFSQRAGDVGARHDASHFQASIVQLTTG-SIRVFGANNFPASV 256 A + L+ F + + A + L + VFG N+ + Sbjct: 143 DLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPL--LLTTLIDPRHMLVFGPNSLFQEI 200 Query: 257 LGAVGVDRPAAQRFTDKPYLEIGATDADLAKNPDLSVADADVVYLSCATPAAADRAATVL 316 L G+ A Q T+ + D LA D DV+ D Sbjct: 201 LDEYGI-PNAWQGETNFWGSTAVSID-RLAA-----YKDVDVLCFDHDNSKDMDALMA-- 251 Query: 317 DSGPWRKLSANRDNRVYVVNDEIWQTGQGLIAAR 350 + W+ + R R V +W G L A Sbjct: 252 -TPLWQAMPFVRAGRFQRVPA-VWFYGATLSAMH 283
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 27.9 bits (62), Expect = 0.014 Identities = 11/41 (26%), Positives = 17/41 (41%), Gaps = 5/41 (12%) Query: 71 NRDEIAEFISGMTHYDAGPENIIR-VAARLAAAGWPLAGID 110 + + F+SG D G + + V L GWP+ G Sbjct: 49 TKPPLVIFLSG----DGGWATLDKAVGGILQQQGWPVVGWS 85
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 48.1 bits (114), Expect = 2e-09 Identities = 31/192 (16%), Positives = 57/192 (29%), Gaps = 18/192 (9%) Query: 7 RQRRRELLDALIAEFAAGGIGDRSLRRVAEAVGTSHRMLLHHFGSREGLLLAIVEEVERR 66 ++ R+ +LD + F+ G+ SL +A+A G + + HF + L I E E Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 67 QMRVLTELPRAPAEGFAAMWAD-----LRRPELREFERLFFECYSR---AAQGEKPFARM 118 + E ++ + L E RL E + Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 119 LPDAVDDWLR---------QAETHSGAPFDPAMAR-LGLAVIRGLLLDLVATGDEAGVDA 168 + + A A + I GL+ + + + Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKK 189 Query: 169 AARAFVNLLNAG 180 AR +V +L Sbjct: 190 EARDYVAILLEM 201
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.9 bits (137), Expect = 5e-12 Identities = 41/195 (21%), Positives = 62/195 (31%), Gaps = 7/195 (3%) Query: 23 RWREHRKKVRNEIVDAAFRAIDRLGPE-LSVREIAEEAGTAKPKIYRHFHDKSDLFQAIG 81 + ++ ++ R I+D A R + G S+ EIA+ AG + IY HF DKSDLF I Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 82 ERLRDMLWTAIFPSIDLKTDSAREVIRRSVEEYVTLVDKHPNVLRVF-IQGRSTGTPQST 140 E + V+R + + + I Sbjct: 64 ELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEM 123 Query: 141 VTILNEGREITLAMADLFDNELREM----ELD-HAAVELAAHAAFGSAASATEWWLGPEP 195 + R + L D + L+ L AA G + E WL Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQ 183 Query: 196 DSPRLMSRAQFVAHL 210 +VA L Sbjct: 184 SFDLKKEARDYVAIL 198
>PF03895#Serum resistance protein DsrA. Length = 79 Score = 29.8 bits (67), Expect = 0.002 Identities = 9/35 (25%), Positives = 17/35 (48%) Query: 32 LARQTAEGISGDMLEIGTYQGKSAILMGYGLRDDE 66 L + G + +G Y+ K+A+ +G G R + Sbjct: 18 LVQPNGVGKTSVSAAVGGYRDKTALAIGVGSRITD 52
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 162 bits (411), Expect = 3e-49 Identities = 74/335 (22%), Positives = 123/335 (36%), Gaps = 38/335 (11%) Query: 31 RVLITGGAGFLGAHLCARLLDDGVEVVSVDDLSTS-GPAVRFG-----DRPGYRFVQRDV 84 + L+TG AGF+G H+ RLL+ G +VV +D+L+ +++ +PG++F + D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 85 CEPGLIDEV--GSGFDAVFHLASAASPVDYQ-RRPIQTLCTGSAGTATALEIAERAG-AR 140 + + ++ F+ VF + V Y P + G LE Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLA-VRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 141 FVLASTSEVYGDPESHPQRESYWGNVNPAGPRSVYDEAKRFAEALTFAYHRLGRADVGAA 200 + AS+S VYG P + P S+Y K+ E + Y L Sbjct: 121 LLYASSSSVYGLNRKMPFSTDD----SVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 201 RIFNTYGPGMRADDGRMVP-TFCLQALRGDPLTVSGTGLQTRSLCYVDDTITGLIALAHS 259 R F YGP R D M F L G + V G R Y+DD +I L Sbjct: 177 RFFTVYGPWGRPD---MALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDV 233 Query: 260 DFAGP-------------------VNIGNPTELTVLSAAELIRELAGSTSTIQFTPPAAD 300 NIGN + + ++ + + + G + P Sbjct: 234 IPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPG 293 Query: 301 DPQRRCPDIRLARKRLGWRPRVDYRTGLSTTLAWF 335 D D + + +G+ P + G+ + W+ Sbjct: 294 DVLETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 50.8 bits (121), Expect = 1e-09 Identities = 41/178 (23%), Positives = 69/178 (38%), Gaps = 12/178 (6%) Query: 18 VVGASSGLGRCIGVGLAQRGDRVA---LLARRRQRIEAAAKDAGPGAVAIECDVTDQASC 74 + GA+ G+G + LA +G +A + +++ ++ K A A DV D A+ Sbjct: 13 ITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAAI 72 Query: 75 ASAIGEAADALGGIDNIVYTPAV---GPLVRMVDTDADTWRRIFDTNVIGA-SLVTAAAV 130 +G ID +V V G + + D + W F N G + + + Sbjct: 73 DEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEE---WEATFSVNSTGVFNASRSVSK 129 Query: 131 PHLSASAGKAVYLSSDAGAFGPPWPGLGAYGVSKAALERLVEAWRAEHPDIGFTCLIV 188 + +G V + S+ G P + AY SKAA + E + C IV Sbjct: 130 YMMDRRSGSIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185
>PF06580#Sensor histidine kinase Length = 349 Score = 33.7 bits (77), Expect = 0.002 Identities = 15/79 (18%), Positives = 28/79 (35%), Gaps = 11/79 (13%) Query: 473 VSNAVRH-----SGASRLTVQI-GVADMFTLDVIDNGRGIASGNTRRS--GLANMTRRAE 524 V N ++H ++ ++ TL+V + G + GL N+ R + Sbjct: 264 VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQ 323 Query: 525 QLGG---SCEISSPPGGGT 540 L G ++S G Sbjct: 324 MLYGTEAQIKLSEKQGKVN 342
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.6 bits (173), Expect = 2e-16 Identities = 25/102 (24%), Positives = 42/102 (41%), Gaps = 2/102 (1%) Query: 3 KVFLVDDHEVVRRGLCDLLSSDPDLQIVGEAGTVAEAKARIPAARPDVAVLDVRLPDGNG 62 + + DD +R L LS + A I A D+ V DV +PD N Sbjct: 5 TILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 63 IELCRDLLSEHPDLRCLMLTSFTSDEAMLEAILAGASGFVIK 104 +L + PDL L++++ + ++A GA ++ K Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK 104
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 78.1 bits (192), Expect = 7e-20 Identities = 33/171 (19%), Positives = 61/171 (35%), Gaps = 15/171 (8%) Query: 31 RGNRLPRDERRGQLLVVASDVFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSKLELYLAV 90 R + E R +L VA +F +G + + EIA AGV++ +Y HF K +L+ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 91 LARHVENLVSGVQQALS-TTKDNRRRLHAAVQAFFDFIEHD--SQGYRLIFENDYVTEPE 147 N+ + + D L + + + + I + E Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 148 VAAQLRVATESCIDAVYALISE-----------DSGLDPHRARMIAVGLVG 187 +A + C++ Y I + + L RA +I G + Sbjct: 123 MAVVQQAQRNLCLE-SYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYIS 172
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.1 bits (60), Expect = 0.009 Identities = 16/67 (23%), Positives = 27/67 (40%), Gaps = 13/67 (19%) Query: 14 LVLTSTQTPDEVEELVSAALSDGSDLLRLSDERGRRFLVHTSKIAYVEIGIADVRRVGFG 73 + T + P+E ++ SDGS ++RL D +A VE+G + + Sbjct: 235 IAQTRFKNPEEFGKVTLRVNSDGS-VVRLKD------------VARVELGGENYNVIARI 281 Query: 74 VGAEVVG 80 G G Sbjct: 282 NGKPAAG 288
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.5 bits (141), Expect = 9e-13 Identities = 18/103 (17%), Positives = 40/103 (38%), Gaps = 3/103 (2%) Query: 5 RRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 + + ++ R +L + +F ++ + EIA+ AGV+R +Y +F DK F+ + Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 65 KDEADRL--YENTNMDDVTGLTMYEEIRVGVLAYMAYHEQNPE 105 + + E G +R ++ + Sbjct: 64 ELSESNIGELELEYQAKFPG-DPLSVLREILIHVLESTVTEER 105
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 36.5 bits (84), Expect = 2e-04 Identities = 19/130 (14%), Positives = 29/130 (22%) Query: 328 QPPLPAPVAEPATPSAAAPTGLPATAGATPIAASAAASGPAPAPTPAPTAATVSSPAPPA 387 QP VA A P P AP P P Sbjct: 48 QPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP 107 Query: 388 PPAPGAAPFAPPYAVPPPGAGFGSKARASVDTRAKSKSPQPDSNAVGAGAAVREAAHARR 447 P + F + A A + + + +V +G + Sbjct: 108 VKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQY 167 Query: 448 RQRSRRRGDE 457 R++ E Sbjct: 168 PARAQALRIE 177
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 90.1 bits (223), Expect = 3e-23 Identities = 60/193 (31%), Positives = 94/193 (48%), Gaps = 3/193 (1%) Query: 46 AVGGRTVLVTGASYGIGEATARRLAAAGATVLVVARSEERLGELTAAINAGGGRAVAYPT 105 + G+ +TGA+ GIGEA AR LA+ GA + V + E+L ++ +++ A A A+P Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 106 DLTDESAVSALTKQITEEHGPLDVVVSNAGKSLRRSLHHQYDRPHDFQRTIDVNYLGPVR 165 D+ D +A+ +T +I E GP+D++V+ AG LR L H +++ T VN G Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAG-VLRPGLIHSLSD-EEWEATFSVNSTGVFN 122 Query: 166 LLLGLLPAMRDNGRGHVVNVSSVGVRVVPGPQWGAYQASKGAFDRWLRSVAPELHADGVH 225 + M D G +V V S VP AY +SK A + + + EL + Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAG-VPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 226 VSTVYFALVRTRM 238 + V T M Sbjct: 182 CNIVSPGSTETDM 194
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 27.9 bits (62), Expect = 0.011 Identities = 7/34 (20%), Positives = 17/34 (50%) Query: 52 LTATVTAGPARADQAAFLNDLHNAGIHAVNGGDD 85 L +V + AF+ ++ AG+ ++G ++ Sbjct: 69 LNISVETTMESSGDVAFICEVKQAGVFTISGLEE 102
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 44.6 bits (105), Expect = 5e-07 Identities = 29/121 (23%), Positives = 42/121 (34%), Gaps = 3/121 (2%) Query: 371 ISVPEPVAAPKPLSLPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPV 430 V E A +P+S+ + P PP A P PE P P P+ PP PV + Sbjct: 33 HQVIELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPE---PIPEPPKEAPVVI 89 Query: 431 RIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTP 490 P P P P+ + + + V+P P P + S T + Sbjct: 90 EKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSV 149 Query: 491 P 491 Sbjct: 150 A 150 Score = 41.1 bits (96), Expect = 6e-06 Identities = 30/124 (24%), Positives = 39/124 (31%), Gaps = 7/124 (5%) Query: 368 QPKISVPEPVAAPKPLSLPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVP 427 P + P V P L + P P P PE PIP P PV + P P P Sbjct: 38 LPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVV-IEKPKPKP 96 Query: 428 VPVRIPVPDPVSPPQLLAPP---RLSVPQPVQPPVRVPQPP---SPPQVGGTVPQSPPQH 481 P PV P+ P R + P P R+ + + +V P Sbjct: 97 KPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRAL 156 Query: 482 QTPP 485 Sbjct: 157 SRNQ 160 Score = 36.9 bits (85), Expect = 2e-04 Identities = 29/129 (22%), Positives = 35/129 (27%), Gaps = 8/129 (6%) Query: 339 VALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSLPVAAPLPAAPPPA 398 V P P Q + V P QA P P+ V P P P Sbjct: 35 VIELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPI-------PEPPKEAPV 87 Query: 399 APPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPP 458 P+ P P PV V PV R P + P L + +P Sbjct: 88 VIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAA-TSKPV 146 Query: 459 VRVPQPPSP 467 V P Sbjct: 147 TSVASGPRA 155 Score = 32.3 bits (73), Expect = 0.005 Identities = 20/103 (19%), Positives = 29/103 (28%), Gaps = 8/103 (7%) Query: 351 VPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSLPVAAPL--------PAAPPPAAPPL 402 E P P P+ + + + +P PKP PV P PA+P Sbjct: 67 PVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFE 126 Query: 403 PEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLA 445 AP + P + P P + A Sbjct: 127 NTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQA 169 Score = 30.3 bits (68), Expect = 0.019 Identities = 21/80 (26%), Positives = 33/80 (41%), Gaps = 2/80 (2%) Query: 419 VVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQV--GGTVPQ 476 + +P P+ V + P + PPQ + PP V +P P +P+PP V P+ Sbjct: 36 IELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPK 95 Query: 477 SPPQHQTPPGEGTPPKPDSP 496 P+ + PK D Sbjct: 96 PKPKPKPVKKVQEQPKRDVK 115
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 51.0 bits (122), Expect = 2e-08 Identities = 49/288 (17%), Positives = 105/288 (36%), Gaps = 46/288 (15%) Query: 151 SYESVAAVRKIVDSTPA--PPGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVML 208 + ++ A++ + P G+K +T SI + +I+++F+++ Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSI---HEVVKTLFEAIMLVFLVM 355 Query: 209 LVVYRSIVTTVLSLVIIGIELFAAQGITATAG-NLNIIGLTPYAVSMITMLSIAAGTDYV 267 + +++ T++ + + + L I A G ++N + + L+I D Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMV------LAIGLLVDDA 409 Query: 268 IFLLGRYHEARSFGQDREEAFYTAYHGVSHVILGSGLTIAGACLCLTAARLP-------- 319 I ++ R +D+ +S + + G + L+A +P Sbjct: 410 IVVVENVE--RVMMEDKLPPKEATEKSMSQI----QGALVGIAMVLSAVFIPMAFFGGST 463 Query: 320 --YFQTMGLPCAIAMVVIVLAALTLAPAILAV-------------GSRFGLFDPKRAIDV 364 ++ + AM + VL AL L PA+ A G FG F+ V Sbjct: 464 GAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSV 523 Query: 365 RGWRKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYVPNYDDQKFTPKD 412 + ++ +++ A I V G + L +P F P++ Sbjct: 524 NHYTNSVGKILGSTGRYLLIYALI-VAGMVVLFLRLP----SSFLPEE 566 Score = 38.3 bits (89), Expect = 2e-04 Identities = 51/261 (19%), Positives = 93/261 (35%), Gaps = 27/261 (10%) Query: 684 FKNPDFKRGLKMFVSPDGTAVRF---------------IITHQGDPASVEGIKHVAGVKD 728 FKNP+ + + V+ DG+ VR I G PA+ GIK G Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 729 -AVADAIKGTPLESSKVYLAG----TASMYSDMQEGVIIDLLVAGISCLILIFTIMLIIT 783 A AIK E + G + + I +++ ++L+F +M + Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 784 RSVVAALVIVGTVAASLGTACGLSVLMWQDLIGLGVQWIVLPLSIVILLAVGSDYNLLLV 843 +++ A L+ V L + + L + +VL + +++ A+ N V Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN---V 416 Query: 844 SRLKEEIPAGLNTGIIRGMGASGRVVTAAGLVFAFT---MASMIVSQLRVIGELGTTIAL 900 R+ E + M + +V + MA S + + TI Sbjct: 417 ERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVS 476 Query: 901 GLLVDTLIVRSFMTPSIAAAL 921 + + L+ TP++ A L Sbjct: 477 AMALSVLVALIL-TPALCATL 496
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 69.3 bits (169), Expect = 1e-16 Identities = 28/168 (16%), Positives = 58/168 (34%), Gaps = 8/168 (4%) Query: 16 QRTEGRLDRSRDPAILDAALAALAEHGYDATNMNDIAARAGVGKAAIYRRWSSKAALMTD 75 ++T+ +R ILD AL ++ G +T++ +IA AGV + AIY + K+ L ++ Sbjct: 3 RKTKQEAQETRQ-HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 76 AL----IYWRPELLNDDAPDTGSLAGDLDAIVKRAKRNDNALISNDLVLRV---ALEAAH 128 L A G L I+ + L++ + E Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 129 DPELATALNDLILFKGRRVLSAVLAQAADRGEIDPNRDWSLVADVLTA 176 + + + + + L + + + A ++ Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRG 169
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 32.0 bits (72), Expect = 0.010 Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 5/80 (6%) Query: 273 ILPALGYLHSIGLVYNDLKPENIMLTEEQLK--LIDLGAVSRINSFGYLYGTPGFQAPE- 329 +L +L G+V+ND+KP N++ + +IDLG SR + T F+APE Sbjct: 254 LLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGF-TESFKAPEL 312 Query: 330 -IVRTGPTVATDIYTVGRTL 348 + G + +D++ V TL Sbjct: 313 GVGNLGASEKSDVFLVVSTL 332
>PF07824#Type III secretion chaperone Length = 120 Score = 28.0 bits (62), Expect = 0.013 Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 37 PNPSDINTLAASLSKGYGLNICTAGNIDRGRQLAVL 72 P +IN L +LS Y IC A + + G +A L Sbjct: 49 ALPENINDLIYALSLNYSEKICLATDDEGGSLIARL 84
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 51.6 bits (123), Expect = 2e-10 Identities = 21/97 (21%), Positives = 35/97 (36%) Query: 12 ILDAARALVLDGGPRAASVAAIAKASGAPAGTLYHRFGNRDGILTAAWLRALERFQARAL 71 ILD A L G + S+ IAKA+G G +Y F ++ + + W + L Sbjct: 16 ILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELEL 75 Query: 72 AADGDTPEDTAVAMAVAAVGFARALPDDARLLLTIRP 108 P D + + + + R L + Sbjct: 76 EYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEI 112
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 57.8 bits (139), Expect = 7e-12 Identities = 55/209 (26%), Positives = 89/209 (42%), Gaps = 20/209 (9%) Query: 21 GRVVVITGANTGIGYETAAVLAHRGAHVVLAVRDLEKGNAALSRIVAASPNADVTLQQLD 80 G++ ITGA GIG A LA +GAH+ + EK +S + A + +A+ D Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF--PAD 65 Query: 81 LASLASVRSAAEALRAAYPRIDLLINNAGV--MWTPKQVTEDGFELQFGTNHLGHFALTG 138 + A++ + ID+L+N AGV ++++ +E F N G F + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 139 LLLDHLLGVRDSRVVTVSSLGHRLRAAIHFDDLHWERRYDRVAAYGQSKLANLLFTYELQ 198 + +++ R +VTV S + R +AAY SK A ++FT L Sbjct: 126 SVSKYMMDRRSGSIVTVGS-----------NPAGVPRT--SMAAYASSKAAAVMFTKCLG 172 Query: 199 RRLAAAPDAKTIAVAAHPGGSNTELARHL 227 LA I PG + T++ L Sbjct: 173 LELAEYNIRCNI---VSPGSTETDMQWSL 198
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 46.5 bits (110), Expect = 2e-08 Identities = 28/176 (15%), Positives = 63/176 (35%), Gaps = 10/176 (5%) Query: 17 RRWHQHKVDRRNELVDGTIDAIRRLG-GALSMDEIAAEIGVSKTVLYRYFVDKNDLTTAV 75 R+ Q + R ++D + + G + S+ EIA GV++ +Y +F DK+DL + + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 76 MMRFTQTTLIPNMAAALTSGLDGFDLTREVIRVYVETVANEPEPYRFVMSNSSASKS--- 132 + D + RE++ +E+ E + + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 133 -KVIADSERIIARMLAVLMRRRMQHAGMDTGGVEPW-----AYLIVGGVQLATHSW 182 V+ ++R + + + ++H A ++ G + +W Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENW 178
>PERTACTIN#Pertactin signature. Length = 922 Score = 32.4 bits (73), Expect = 0.003 Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 2/57 (3%) Query: 41 PGQAPGQVPPPPPAPAPPPPGQTERFGAPRPQMQQPGYPPPPTPPAGPTERLATAPN 97 P P P P P P PP P Q + P Q+ P P PPAG L+ A N Sbjct: 569 PAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAG--RELSAAAN 623 Score = 30.8 bits (69), Expect = 0.008 Identities = 24/64 (37%), Positives = 27/64 (42%), Gaps = 4/64 (6%) Query: 35 RINTGGPGQAPGQVPPPPPAPAPPPPGQTERFGAPRPQMQQPGYPPPPTPPAGPTERLAT 94 R+ G GQ PPAP P P + P PQ QP PP P P P +R Sbjct: 551 RLAANGNGQWSLVGAKAPPAPKPAPQPGPQ----PGPQPPQPPQPPQPPQPPQPPQRQPE 606 Query: 95 APNP 98 AP P Sbjct: 607 APAP 610
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 30.3 bits (68), Expect = 0.016 Identities = 17/98 (17%), Positives = 32/98 (32%), Gaps = 6/98 (6%) Query: 287 AAFGGRAEVMERLAPLGPVYQAGTLSGNPVAMAAGLATLRHADAAAYAALDANADRL-AR 345 A+ + + +E L L + + A+A +A + A Y L +N Sbjct: 4 ASTATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGG 63 Query: 346 LLSDALTNAGVPHQIPRAGNMLSVFFTDTPVTDFASAR 383 + LT +P++ + V P R Sbjct: 64 AIVAQLTQMNIPYRFANGSGAIEV-----PADKVHELR 96
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.6 bits (66), Expect = 0.032 Identities = 18/74 (24%), Positives = 27/74 (36%), Gaps = 4/74 (5%) Query: 16 TTQIPPAAAAGDEKKDAAEPQPEPGGDAPTKAFAGFRTERRVPAPEREPAPPTAPRPGGM 75 T+Q+ P + + AEP E PT +++ A +PA T Sbjct: 1126 TSQVSPKQEQSETVQPQAEPAREN---DPTVNIKEPQSQTNTTADTEQPAKET-SSNVEQ 1181 Query: 76 PPWDSTPVTGIPRV 89 P +ST V V Sbjct: 1182 PVTESTTVNTGNSV 1195
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 91.4 bits (227), Expect = 6e-25 Identities = 38/132 (28%), Positives = 55/132 (41%), Gaps = 12/132 (9%) Query: 1 MRVLVTGAAGFIGSRVAAALRAAGHDVVAVDALLAAAHGPN---------PLPPNGCHRV 51 M+ LVTGAAGFIG V+ L AGH VV +D L + + P H++ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDN-LNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 52 DVRDADALAPLLA--GVDVVCHQAAMVGAGVDAADAPAYGGHNDLATTVLLAQMFAAGVR 109 D+ D + + L A + V + + AY N +L ++ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 110 RLVLASSMVVYG 121 L+ ASS VYG Sbjct: 120 HLLYASSSSVYG 131
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 81.0 bits (200), Expect = 4e-21 Identities = 38/157 (24%), Positives = 58/157 (36%), Gaps = 23/157 (14%) Query: 1 MVALRYHNVYGPGMPRDTPYSGVAAIFRSALEKGEPPRVFEDGGQMRDFVHVDDVAAANL 60 LR+ VYGP D F A+ +G+ V+ G RDF ++DD+A A + Sbjct: 173 ATGLRFFTVYGPWGRPDMALF----KFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAII 228 Query: 61 AAL------------------ACRDGFTAVNVCSGQPISILQVATALCDARGGAVAPVVT 102 A + N+ + P+ ++ AL DA G A Sbjct: 229 RLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIE-AKKNM 287 Query: 103 GQYRSGDVRHIVADPSRAARLLGFRAAVQPGDGLREF 139 + GDV AD ++GF DG++ F Sbjct: 288 LPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNF 324
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 34.7 bits (79), Expect = 0.001 Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 28/122 (22%) Query: 358 QNGTPGKFMPILPSQQQAPLPPPPADAPNAGFQGGVVQAPSNAPAPQ--PAVPAPANPAP 415 +NG P + + Q P G +AP+ P P+ PA NPAP Sbjct: 284 RNGNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAP 343 Query: 416 EAPSNPGVVPNPNPGWAPNPNPLVPVPIPIPVPIPGWNPPYNP-----PYTPPYNPTTPY 470 NPG PNP P P NP NP P T P +P P Sbjct: 344 N--ENPGTRPNPEPD-------------------PDLNPDANPDTDGQPGTRPDSPAVPD 382 Query: 471 TP 472 P Sbjct: 383 RP 384
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 74.7 bits (183), Expect = 8e-18 Identities = 49/178 (27%), Positives = 83/178 (46%), Gaps = 3/178 (1%) Query: 38 LAGKRVLLTGASSGIGEAAAEQFAREGARVVVVARRKDLLDALAERITRAGGEAIAMPCD 97 + GK +TGA+ GIGEA A A +GA + V + L+ + + A A P D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 98 ISDLDAADALVADVQQRLGGVDILINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRL 157 + D A D + A +++ +G +DIL+N AG + RP + E T +N Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAG--VLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 158 IRGIAPGMIERGDGHIINVSTWGVLSEASPLFAVYNASKAALSTVSRVVETEWGDKGV 215 R ++ M++R G I+ V + + + A Y +SKAA ++ + E + + Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSM-AAYASSKAAAVMFTKCLGLELAEYNI 180
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.8 bits (147), Expect = 1e-13 Identities = 32/169 (18%), Positives = 64/169 (37%), Gaps = 16/169 (9%) Query: 33 GRSDARRNRQRLLEAATAAFTAHG-ASVSLESIARDAGVGIGTLYRHFPNREALVEAVYR 91 + +A+ RQ +L+ A F+ G +S SL IA+ AGV G +Y HF ++ L ++ Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 92 AELAEVAAAAAQLLQRHP--PKTALRRWMDRYANFVATKRG-------------MAESLQ 136 + + + + P P + LR + T+ + Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 137 AIFESGALVPSQTRDSIVGAVETLLRAGADDASLRADVQADDVVSSLIG 185 + ++ + ++ D I ++ + A A L A + + G Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG 173
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 33.9 bits (78), Expect = 0.002 Identities = 14/30 (46%), Positives = 18/30 (60%) Query: 527 DDVIGSLEVGKYADLVVLSADPRAVPPERI 556 IGSLEVGK ADLV+ + V P+ + Sbjct: 420 SHEIGSLEVGKRADLVLWNPAFFGVKPDMV 449
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 28.3 bits (63), Expect = 0.025 Identities = 26/110 (23%), Positives = 39/110 (35%), Gaps = 10/110 (9%) Query: 80 DFSVGMLAAGAARRVPKVAGDATRLPFADDVFDAVTISFGLRNVVDTQAALREMARVTRP 139 F+V + G + V +P A D + R V T A R++A + R Sbjct: 89 GFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLLRQ 148 Query: 140 ------GGRLVVCEFSTPSNALFATVYKEYLMRALPRVARAVSSNPDAYV 183 G +V E PSN L T ++ L + V + D V Sbjct: 149 LNDNAGVGSVVHYE---PSNVLLMTGRAAV-IKRLLTIVERVDNAGDRSV 194
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 388 bits (998), Expect = e-136 Identities = 110/373 (29%), Positives = 173/373 (46%), Gaps = 28/373 (7%) Query: 17 AEALVDLGAIEHNVRLLCEQARGAQVMAVVKADGYGHGAVQTARAALAAGAAELGVATVD 76 +A +DL A++ N+ ++ + A A+V +VVKA+ YGHG + A A + ++ Sbjct: 5 IQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDG--FALLNLE 62 Query: 77 EALALRAAGISAPVL---AWLHPPGIDFRPALLAGVQIGLSSQRQLDELLTAVRDTGRTA 133 EA+ LR G P+L + H ++ + + S QL L A Sbjct: 63 EAITLRERGWKGPILMLEGFFHAQDLEIYDQ--HRLTTCVHSNWQLKALQNA--RLKAPL 118 Query: 134 TVTVKVDTRLNRNGVPPAQYPSMLTALRRAVAEEAIVPRGLMSHMVYADQPANPVNDVQA 193 + +KV++ +NR G P + +LT ++ A + LMSH A+ P Sbjct: 119 DIYLKVNSGMNRLGFQPDR---VLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISG--AM 173 Query: 194 QRFTDMLAQAREQGVRFEVAHLSNSSATMSRPDLAFDMVRPGIAVYGLSPVPELGDM--- 250 R + +G+ LSNS+AT+ P+ FD VRPGI +YG SP + D+ Sbjct: 174 ARI-----EQAAEGLECRR-SLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANT 227 Query: 251 GLVPAMTVKCTVALVKSIRAGESVSYGHTWTAQRDTNLALLPVGYADGIFRSLGGRLQVS 310 GL P MT+ + V++++AGE V YG +TA+ + + ++ GYADG R V Sbjct: 228 GLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVL 287 Query: 311 INGRRRPGVGRICMDQFVVDLGPGRPDVAEGDEAILFGPGSNGEPTAQDWADLLGTIHYE 370 ++G R VG + MD VDL P P G L+G E D A GT+ YE Sbjct: 288 VDGVRTMTVGTVSMDMLAVDLTPC-PQAGIGTPVELWGK----EIKIDDVAAAAGTVGYE 342 Query: 371 VVTSPRGRITRTY 383 ++ + R+ Sbjct: 343 LMCALALRVPVVT 355
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 47.6 bits (113), Expect = 2e-09 Identities = 18/92 (19%), Positives = 31/92 (33%), Gaps = 6/92 (6%) Query: 53 GARVGDTLVGYAGISRLGRVPPYEYEIHTIGVDPAYQGRGIGRLMLDRLLEFA---DGGV 109 + + +G I I I V Y+ +G+G +L + +E+A Sbjct: 69 LYYLENNCIGRIKIRSNWNGYAL---IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCG 125 Query: 110 VYLEVRTDNEPAIGLYRSVGFEQIGLRRRYYR 141 + LE + N A Y F + Y Sbjct: 126 LMLETQDINISACHFYAKHHFIIGAVDTMLYS 157
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 27.2 bits (60), Expect = 0.026 Identities = 12/67 (17%), Positives = 21/67 (31%), Gaps = 3/67 (4%) Query: 67 GHRPPPARRTFSSGQRALLWAAGVLGALAIIIAVLI---VINSRADQQQQPPTVTDTGTP 123 G RP + Q + G + + + + +QQ+ +TD Sbjct: 102 GTRPDEKQYDTVETQLRFMTENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPAA 161 Query: 124 PASAPPP 130 P PP Sbjct: 162 PDENLPP 168
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 27.7 bits (61), Expect = 0.019 Identities = 17/56 (30%), Positives = 25/56 (44%), Gaps = 6/56 (10%) Query: 88 AAVAIGSLSYAATLQALTGRLPGNTDEDRYFEAWVNQTVSVLAQYTNRRKPLNDND 143 AA A+ +LS A D+ +Y W +Q+V+V+ Y R P ND Sbjct: 7 AAGAVVALSTTFAAGA------AENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRND 56
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.1 bits (127), Expect = 2e-12 Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 2/51 (3%) Query: 14 RDRLLSAALRLFAAKGYAATSVADIQRESGLAPGSGALYKHFGSKRELLEA 64 R +L ALRLF+ +G ++TS+ +I + +G+ GA+Y HF K +L Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTR--GAIYWHFKDKSDLFSE 61
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 123 bits (309), Expect = 3e-33 Identities = 56/259 (21%), Positives = 99/259 (38%), Gaps = 63/259 (24%) Query: 239 GVVGVAPHATIISIRQSSRAFEPVNPPPGDPNSDEKVKAGTLNSVARAVVHAANMGAKVI 298 GVVGVAP A ++ I+ + K +G + + + + +A +I Sbjct: 102 GVVGVAPEADLLIIKVLN-----------------KQGSGQYDWIIQGIYYAIEQKVDII 144 Query: 299 NISVTACLPAAAPADQRALGAALWYAATVKDAVVVAAAGNDGEAGCNNNPMFDLLDPSDP 358 ++S+ P D L A+ A +V+ AAGN+G+ + Sbjct: 145 SMSL------GGPEDVPELHEAVKKA-VASQILVMCAAGNEGDGDDRTDE---------- 187 Query: 359 RDWHQVKVVSAPSWFSDYVLSVGAVDASGAALDKSMSGPWVGVAAPGTHIMGLSPQGGGP 418 + P + + V+SVGA++ A + S S V + APG I+ P G Sbjct: 188 --------LGYPGCY-NEVISVGAINFDRHASEFSNSNNEVDLVAPGEDILSTVPGG--- 235 Query: 419 VNAYPPSRPGEKNMPFWGTSFSAAYVSGVAALVRAKFP-----ELSAHQVINRIVQSAHN 473 K F GTS + +V+G AL++ +L+ ++ ++++ Sbjct: 236 -----------KYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRT-I 283 Query: 474 PPAGVDNKVGYGLVDPVAA 492 P G GL+ A Sbjct: 284 PLGNSPKMEGNGLLYLTAV 302 Score = 64.1 bits (156), Expect = 3e-13 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 8/101 (7%) Query: 52 MRRANSCSAPITVRN-PDVAQLAPGFNLLNIAKAWQYSTGNGVPVAVIDTGVSPN-PRLP 109 M R ++ V ++ G ++ W + G GV VAV+DTG + P L Sbjct: 1 MERKVHIIPYQVIKQEQQVNEIPRGVEMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLK 60 Query: 110 --VVPGGDYIMGEDG----LSDCDAHGTIVSSIIGAAPQGI 144 ++ G ++ ++G D + HGT V+ I A Sbjct: 61 ARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENEN 101
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 30.1 bits (68), Expect = 0.008 Identities = 12/30 (40%), Positives = 16/30 (53%) Query: 1 MTIVVTGATGNVGRPLVTALLAAGAPVRAV 30 M +VTGA G +G + LL AG V + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGI 30
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 44.2 bits (104), Expect = 3e-07 Identities = 28/139 (20%), Positives = 39/139 (28%), Gaps = 6/139 (4%) Query: 13 QPERPSARPAPEAPPPPVAPRPAPPPRPPTPAPTPPTRPPAPPTFRPHPPAAAPAPAAPP 72 P P P PE P P P+ AP P P +P Sbjct: 68 PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPAS 127 Query: 73 TPRPQPSATPQLPDRGWRRALRLATFGLIDLGPSPAQRREAQF-EQAIQARLYGNYKVG- 130 A P A + GP R + Q+ +A R+ G KV Sbjct: 128 PFENTAPARPTSSTAT---AATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 184 Query: 131 -VLGKGGVGKTSVAASVGS 148 V G V + ++ + Sbjct: 185 DVTPDGRVDNVQILSAKPA 203 Score = 36.1 bits (83), Expect = 2e-04 Identities = 22/72 (30%), Positives = 27/72 (37%), Gaps = 4/72 (5%) Query: 18 SARPAPEAPPPPVAPRPA--PPPRPPTPAPTPPTRPPAPPTFRPHPPAAAP--APAAPPT 73 PAP P PA PP+ P P P P P P PP AP P Sbjct: 41 IELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPK 100 Query: 74 PRPQPSATPQLP 85 P+P+P ++ Sbjct: 101 PKPKPKPVKKVE 112 Score = 35.3 bits (81), Expect = 2e-04 Identities = 15/86 (17%), Positives = 21/86 (24%) Query: 6 EFLRDRLQPERPSARPAPEAPPPPVAPRPAPPPRPPTPAPTPPTRPPAPPTFRPHPPAAA 65 E +P+ R P +P T P P + + Sbjct: 89 EAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSK 148 Query: 66 PAPAAPPTPRPQPSATPQLPDRGWRR 91 P + PR PQ P R Sbjct: 149 PVTSVASGPRALSRNQPQYPARAQAL 174
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 29.8 bits (67), Expect = 0.048 Identities = 17/81 (20%), Positives = 30/81 (37%), Gaps = 4/81 (4%) Query: 228 RFSTNTFPSWPLAHPFRRIAHNGE---INTVTGNENWM-RAREALIKTDVFGTEADVEKL 283 RF+ + L F +I + T+ GN + + L ++ GT + + Sbjct: 69 RFNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEEIMGTICGDDTI 128 Query: 284 FPICTPGASDTARFDEVLELL 304 IC ++LELL Sbjct: 129 LIICRTHDDTKVVQKKILELL 149
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 29.7 bits (66), Expect = 0.026 Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 13/103 (12%) Query: 25 PSLVDALLAADAARRAAISTADTLRAEQKSASKSVGAAS-----PEQRPALLARAK---- 75 PS + A +AA +A +AE+K A K AA EQR + R K Sbjct: 110 PSATELAHANNAAMQAEDERLRLAKAEEK-ARKEAEAAEKAFQEAEQRRKEIEREKAETE 168 Query: 76 ---ELAEQVKAAETAQAEAEAAFTAAHLAISNVVIDGVPAGGE 115 +LAE + A +E A A +S + V GE Sbjct: 169 RQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGE 211
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 30.4 bits (68), Expect = 0.005 Identities = 11/67 (16%), Positives = 22/67 (32%), Gaps = 2/67 (2%) Query: 149 LRAACALLADNLRKPLTLRQIGERIGVGQRTLSRLF--RDELAMTFPQWRTQVRLQHALV 206 L A L + +L +I + GV + + F + +L + + L Sbjct: 17 LDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELE 76 Query: 207 LLAERRD 213 A+ Sbjct: 77 YQAKFPG 83
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.7 bits (139), Expect = 1e-12 Identities = 40/188 (21%), Positives = 68/188 (36%), Gaps = 14/188 (7%) Query: 1 MVRPAQTARSERTREALRQAALVRFLAQGVEDTSAEQIAADAGVSLRTFYRHFRSKHDLL 60 M R + ++ TR+ + AL F QGV TS +IA AGV+ Y HF+ K DL Sbjct: 1 MARKTK-QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 61 FADYTGLH-----WFRAALDARPAD-EPIIDSVQAAIFSFPYDVDAVTKIAA-LRHEELD 113 + P D ++ + + + + + H+ Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 114 PG---RIVRHIRDVQADFAEAIAAQLQRRGRGAGAPTADQRVRAAVTARCIAAAVFGAME 170 G + + R++ + + I L + A AD R A A + + G ME Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTL-KHCIEAKMLPADLMTRRA--AIIMRGYISGLME 176 Query: 171 VWMVGDER 178 W+ + Sbjct: 177 NWLFAPQS 184
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 30.4 bits (68), Expect = 0.019 Identities = 15/42 (35%), Positives = 22/42 (52%) Query: 196 AVNTLYRGPATPGSAAALAFGLGVPDGDTMQMKKLRGGIGVL 237 AVN R P TP ++AL G +G MQ++ + +G L Sbjct: 180 AVNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTL 221
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 102 bits (257), Expect = 2e-27 Identities = 34/117 (29%), Positives = 64/117 (54%) Query: 23 VLVVDDEAVLAEMVSMALRYEGWNIATASDGASAIAAARNQRPDVVVLDVMLPDMSGLDV 82 +LV DD+A + +++ AL G+++ S+ A+ D+VV DV++PD + D+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 83 LHKLREENPQLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRALLRRT 139 L ++++ P LPVL+++A++ I G DY+ KPF + E++ + L Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>FIMBRILLIN#Porphyromonas gingivalis: fimbrillin protein signature. Length = 348 Score = 27.3 bits (60), Expect = 0.026 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 3/78 (3%) Query: 82 AATGIAAVLSDGNPPQVKSVGLGNVNGVTLGYTSGTGQGNASAEKNGNSYKITGTATGVD 141 AA +++D NP V L N N Y +G N E+N + Y I T TG Sbjct: 260 AAFNAGWIVADNNPTTYYPV-LVNFNSNNYTYDNGYTPKN-KIERN-HKYDIKLTITGPG 316 Query: 142 MANPLQPVNKPFEIDVTC 159 NP P+ + ++V C Sbjct: 317 TNNPENPITESAHLNVQC 334
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.3 bits (125), Expect = 1e-10 Identities = 25/161 (15%), Positives = 48/161 (29%), Gaps = 12/161 (7%) Query: 20 RQREATEEVERILAAAVRVMERVAPEPPRVSDIVAEAGSSNKAFYRYFAGKDELILAVME 79 ++EA E + IL A+R+ + + +I AG + A Y +F K +L + E Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 80 RGVAIVVSYLEHQMAKEATPRGKIARWIEGTLAQVADPHLISMTRA----------AAGQ 129 + + AK P ++ E + + R G+ Sbjct: 65 LSESNIGELELEYQAK--FPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 130 MSAGTSWRAADQEMMRPLRELLVEPVAALGSSDVDRDVEAV 170 M+ + E ++ D Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRA 163
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 75.1 bits (184), Expect = 4e-18 Identities = 65/251 (25%), Positives = 104/251 (41%), Gaps = 14/251 (5%) Query: 13 RVVLITGGNRGLGREMAFGAARCGADVVIASRNLDNCVATAQQVEHETGRRAMAYQVHVG 72 ++ ITG +G+G +A A GA + N + ++ E R A A+ V Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADVR 67 Query: 73 RWDQLDGLVEASYDRFGKIDTLINNAGMSPLYDKLTD-VTEKLFDAVVNLNLKGPFRLSA 131 +D + G ID L+N AG+ L L ++++ ++A ++N G F S Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGV--LRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 132 LVGERMVAAGRGSIINVSTAGSLRPTPDIVPYAASKAGLNAMTEALAKAFGP-AVRVNTL 190 V + M+ GSI+ V + + P + YA+SKA T+ L +R N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 191 MAGPFLTDVSRA-WNLEAVQENPFRHLA--------LQRAGDPREIVGAALFLASDASSF 241 G TD+ + W E E + L++ P +I A LFL S + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 242 TTGSILRADGG 252 T L DGG Sbjct: 246 ITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 86.3 bits (213), Expect = 7e-22 Identities = 67/280 (23%), Positives = 111/280 (39%), Gaps = 35/280 (12%) Query: 16 LEGKVAIVTGTSRGVGVGIAHELLRAGATVVG--CARSPLDTIPGIEPDWTERAFQRVCD 73 +EGK+A +TG ++G+G +A L GA + L+ + A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 74 QGDYRGIDAFVTDVVATHGRLDILVNNAGGTVPAPHAESIPELVQRIQGSPAADDDYART 133 D ID + G +DILVN AG P E + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEAT------------- 112 Query: 134 ALFHAFAVQMNLIGPLWFAIRTYRQMQTQDRMGCIINISSGAGHPAGSP--TLVSYGAAK 191 F+V N G + + M + R G I+ + S +PAG P ++ +Y ++K Sbjct: 113 -----FSV--NSTGVFNASRSVSKYMMDR-RSGSIVTVGS---NPAGVPRTSMAAYASSK 161 Query: 192 SGLNHLTRSLAQEWGP-KVRVNCVALGPTMTENFRSFVLPKDDP------TGEKYFAAVP 244 + T+ L E +R N V+ G T T+ S ++ + E + +P Sbjct: 162 AAAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIP 221 Query: 245 LRRAGEPAEVGRICVFLAGGQADFVNGTTIECDGGMLPGV 284 L++ +P+++ +FL GQA + + DGG GV Sbjct: 222 LKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGATLGV 261
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 91.7 bits (227), Expect = 3e-24 Identities = 71/254 (27%), Positives = 114/254 (44%), Gaps = 13/254 (5%) Query: 9 MRGQVAIVTGAAQGVGKGIAAALLERGAAVLLVDIQQETLEATATELRALGRV-ERLVTD 67 + G++A +TGAAQG+G+ +A L +GA + VD E LE + L+A R E D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 68 LRDPDSAPRIAAAAVDAFGSVHGLVNNAIATNEPKAFVDITTDDLALGYEVGPRATFLLM 127 +RD + I A G + LVN A P ++ ++ + V F Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVA-GVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 128 QAVHPLLVKEGGGAIVNLGSGTGTGGEPRWGGYAAAKEGIRGLSKVAALEWGRDNIRVNV 187 ++V ++ G+IV +GS YA++K +K LE NIR N+ Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 188 VCPFAESDGVKLWKQFAPNDYAKAVGR---------VPMKRIGDVRTDVGALVAFLLSTD 238 V P ++ W +A + A+ V + +P+K++ +D+ V FL+S Sbjct: 185 VSP-GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAK-PSDIADAVLFLVSGQ 242 Query: 239 ATFITGQTIHVDGG 252 A IT + VDGG Sbjct: 243 AGHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.7 bits (139), Expect = 1e-12 Identities = 21/80 (26%), Positives = 32/80 (40%) Query: 9 RQRAQIRADIRRAAFRLFVERGYDAVTTEEIATAAGVSPRTFFRHVPAKEELLLAPVRYG 68 ++ + R I A RLF ++G + + EIA AAGV+ + H K +L Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 69 GAAIVHLLEGRPAGESPDVA 88 + I L A D Sbjct: 67 ESNIGELELEYQAKFPGDPL 86
>cloacin#Cloacin signature. Length = 551 Score = 28.1 bits (62), Expect = 0.030 Identities = 17/51 (33%), Positives = 19/51 (37%), Gaps = 7/51 (13%) Query: 56 GPLGFGPGFGPGFGPGF-------GPGFGFGPGGPRGAWRRGGPGRGKRGD 99 GP G G G G G G+ G G G G G+ G G G G Sbjct: 23 GPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGG 73
>PERTACTIN#Pertactin signature. Length = 922 Score = 30.8 bits (69), Expect = 0.006 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 10/80 (12%) Query: 144 GTVVVNERGPRLGPPPAMPPSLAWWASSLQLSGLSSGQAEVARQFLSRAAQLDPGLRLQM 203 G V+ G R PPPA P S+ L +G R L R L L Sbjct: 336 GNVIETGGGARRFPPPASPLSIT----------LQAGARAQGRALLYRVLPEPVKLTLAG 385 Query: 204 AYRIAGDVVARIAPPPPGAP 223 + GD+VA PP PGA Sbjct: 386 GAQGQGDIVATELPPIPGAS 405 Score = 28.5 bits (63), Expect = 0.039 Identities = 16/43 (37%), Positives = 17/43 (39%) Query: 245 PPAPWPAPGYPPAWPGSGPAPQWPAPGPANPGPPEGFSAGFTP 287 PPAP PAP P P P P P P PP+ P Sbjct: 568 PPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAP 610
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 106 bits (265), Expect = 9e-29 Identities = 54/267 (20%), Positives = 102/267 (38%), Gaps = 24/267 (8%) Query: 21 AVLAVTGWAALTGCTGPAHPHATA---VVASTDVWGSVARAVAGGHVAVASILSGSDQDP 77 VL ++ + +G + VVA+ + + + +AG + + SI+ QDP Sbjct: 8 LVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIV-PIGQDP 66 Query: 78 HSYEASPSDAAAIADAGLVVFNG----GGYDGWVDDVLAHHPGVARVDAYALL----PDD 129 H YE P D ++A L+ +NG G + W ++ + D +A+ Sbjct: 67 HEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVDVIY 126 Query: 130 GRPRNE------HVFYHLGVAKAVAAAVADRLAAIDPGNAADYRRNAAAFGRDADAI-AG 182 +NE H + +L A +A +L+A DP N Y +N + D + Sbjct: 127 LEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKE 186 Query: 183 IEHTIAAAHPGGSVVATEPVAF-YLLEASGLVNRTPPALEAAVENETDPAPADLARALDL 241 + ++ T AF Y +A G+ P A + E + P + ++ Sbjct: 187 SKDKFNKIPAEKKLIVTSEGAFKYFSKAYGV----PSAYIWEINTEEEGTPEQIKTLVEK 242 Query: 242 LDRHQVSALVVNPQTSASAVNGLREAA 268 L + +V +L V + + + Sbjct: 243 LRQTKVPSLFVESSVDDRPMKTVSQDT 269
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.6 bits (162), Expect = 2e-15 Identities = 32/198 (16%), Positives = 63/198 (31%), Gaps = 17/198 (8%) Query: 61 GSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALG 120 + +E R+ ILD + + S+ G + + +A A V G +Y +F K L Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 121 REFSRI-DAKTDRAAMTGGTPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASE 179 S I + + + A G P L ++ + + + +F E Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEER--RRLLMEIIFHKCEFVGE 122 Query: 180 VDQVEKLIDS-----------MFARAMADGE--PTEDQYHIARVISDVWLSNLLAWLTRR 226 + V++ + + A ++ + WL Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL-FA 181 Query: 227 ASATDVSKRLDLAVRLLL 244 + D+ K V +LL Sbjct: 182 PQSFDLKKEARDYVAILL 199
>PF04183#IucA / IucC family Length = 580 Score = 30.6 bits (69), Expect = 0.026 Identities = 21/79 (26%), Positives = 32/79 (40%), Gaps = 7/79 (8%) Query: 158 WLVVDTASDGVHIEPLAATDFSRPLARVVLDSAPATVLAQTPERVEELAATVLAAEAAGI 217 WL +D + EP+ A L + VL + ATV E +++L AT+L Sbjct: 57 WLWIDAQTLRCADEPVLAQTLLMQLKQ-VLSMSDATV----AEHMQDLYATLLGDLQLLK 111 Query: 218 TR--WSLQTAVDYAKVREQ 234 R S ++ R Q Sbjct: 112 ARRGLSASDLINLNADRLQ 130
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.6 bits (136), Expect = 3e-12 Identities = 36/188 (19%), Positives = 68/188 (36%), Gaps = 12/188 (6%) Query: 7 DARARLVAAALDLFNERGYDQTTVAEIAERAGLTKSTFFRHFPDKRDVLAA----GQDAI 62 + R ++ AL LF+++G T++ EIA+ AG+T+ + HF DK D+ + + I Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 63 AALLREGIAAAPADATPLALVCSGLKSAAAAFTPFNKELAPRLRAAIAASAELQERNALK 122 L E A P D + + + L + E+ + Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 123 QIG-------LALAVSEALQARGVPEPA-AALAAELGALAVKTAYARWAEPDESGDLGDM 174 + + + ++A+ +P AA + + W +S DL Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKE 190 Query: 175 ACQALREL 182 A + L Sbjct: 191 ARDYVAIL 198
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 51.7 bits (124), Expect = 1e-09 Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 11/82 (13%) Query: 26 RVLVTGASGGIGSAVVKELLAAGHHVIGL---------ARSEASAATVSGLGAEPLRGDI 76 + LVTGA+G IG V K LL AGH V+G+ + +A ++ G + + D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 77 ADLDVLQK--AAVDTDGVAYLA 96 AD + + A+ + V Sbjct: 62 ADREGMTDLFASGHFERVFISP 83
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 30.2 bits (68), Expect = 0.022 Identities = 13/40 (32%), Positives = 19/40 (47%), Gaps = 2/40 (5%) Query: 218 PKDKADRDML-DVLVSIKDEDGKPRFSADEITG-MFISLM 255 P R+ML D L+ I D D R+ D T + +S + Sbjct: 352 PSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFL 391
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 116 bits (291), Expect = 2e-33 Identities = 66/200 (33%), Positives = 105/200 (52%) Query: 9 ERRPAIVAGASSGIGEATAIELAAHGFPVALGARRVEKLNDIVGKINADGGEAVGFHLDV 68 E + A + GA+ GIGEA A LA+ G +A EKL +V + A+ A F DV Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 69 TDPNSVKSFVAQAVDALGDIEVLVAGAGDTYFGKLAEIAGDEFESQLQIHLVGAFRLASA 128 D ++ A+ +G I++LV AG G + ++ +E+E+ ++ G F + + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 129 VLPGMLERQRGDLIFVGSDVALRQRPHMGAYGAAKAALVAMVNNFQMELEGTGVRASVVH 188 V M++R+ G ++ VGS+ A R M AY ++KAA V +EL +R ++V Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 189 PGPTKTAMGWSLPAEKIGPA 208 PG T+T M WSL A++ G Sbjct: 187 PGSTETDMQWSLWADENGAE 206
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 54.6 bits (131), Expect = 2e-11 Identities = 26/198 (13%), Positives = 60/198 (30%), Gaps = 17/198 (8%) Query: 21 PRNRRQEETFRKVLAAGIETLREKSYSDLTVRAVAARAKVAPATAYTYFSSKNHLIAEVY 80 + +ET + +L + ++ S ++ +A A V Y +F K+ L +E++ Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 81 LDLVRQV-PYFTDVNDPMPTRVEQVLR-------HLALVVADEPEVSAACTTALLSGGAD 132 + + P VLR + + G Sbjct: 64 ELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEM 123 Query: 133 PAVRAARDRIGVEIHRRITSAMG---------PDADPTTVSALEMSFFGALVQAGSGEFS 183 V+ A+ + +E + RI + D + + + L++ Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQ 183 Query: 184 YREIADRLAYVVRLILTG 201 ++ V ++L Sbjct: 184 SFDLKKEARDYVAILLEM 201
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 126 bits (317), Expect = 2e-37 Identities = 78/253 (30%), Positives = 114/253 (45%), Gaps = 15/253 (5%) Query: 4 ENKVGIVTGSGGGIGQAYAEALAREGAAVVVADINAEAAEAVAKQIVADGGTAISVAVDV 63 E K+ +TG+ GIG+A A LA +GA + D N E E V + A+ A + DV Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 64 SDPESAKAMADRTLAEFGGIDYLVNNAAIFGGMKLDFLLTIDPEYYKKFMSVNLDGALWC 123 D + + R E G ID LVN A + ++ + ++ E ++ SVN G Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGV---LRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 124 TRAVYKKMTKRGGGAIVNQSSTAA---WLYSNYYGLAKVGINGLTQQLSRELGGRNIRIN 180 +R+V K M R G+IV S A Y +K T+ L EL NIR N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 181 AIAPGPIDTEANRTTTPKEMVDDIV---------KGLPLSRMGTPDDLVGMCLFLLSDEA 231 ++PG +T+ + E + V G+PL ++ P D+ LFL+S +A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 232 SWITGQIFNVDGG 244 IT VDGG Sbjct: 244 GHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 113 bits (284), Expect = 2e-32 Identities = 77/263 (29%), Positives = 127/263 (48%), Gaps = 16/263 (6%) Query: 5 LAGKVAIVTGGASGIGRGIVERFVAEGARVVIADIETERGERLAAELGGEAVFR---RTD 61 + GK+A +TG A GIG + ++GA + D E+ E++ + L EA D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 62 VSDIEQVGALVAAAVEKFGGLHVMVNNAGISSPLRRLLDDDLA--DFHRVMGVNVLGVMA 119 V D + + A + G + ++VN AG+ LR L L+ ++ VN GV Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGV---LRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 120 GTRDAARHMADNGGGTIINLTSIGGIQAGGGVMTYRASKAAVIQFTKAAAIELARYDIRV 179 +R +++M D G+I+ + S + Y +SKAA + FTK +ELA Y+IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 180 NAIAPGNIPTPILGKSAGDMDPEQRERFEARIR---EGMREDRPLKREGTPDDVAEAALY 236 N ++PG+ T + D + E I+ E + PLK+ P D+A+A L+ Sbjct: 183 NIVSPGSTETDMQWSLWADENGA-----EQVIKGSLETFKTGIPLKKLAKPSDIADAVLF 237 Query: 237 FATDRSRYVTGTVLPVDGGTSAG 259 + ++ ++T L VDGG + G Sbjct: 238 LVSGQAGHITMHNLCVDGGATLG 260
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.1 bits (127), Expect = 9e-11 Identities = 22/99 (22%), Positives = 44/99 (44%), Gaps = 1/99 (1%) Query: 11 ERASSTQEAILVAAERLYAEHGMFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHK 70 + A T++ IL A RL+++ G+ + S ++++AAG A+ +HF K+DL I Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGV-TRGAIYWHFKDKSDLFSEIWEL 65 Query: 71 HRGPVEQLREQMVAELLESGAGGGRDAELRSWVACSVRP 109 + +L + A+ R+ + + Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEE 104
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 28.9 bits (64), Expect = 0.035 Identities = 18/84 (21%), Positives = 32/84 (38%), Gaps = 3/84 (3%) Query: 86 VYLEFDEGVAAFARTVADLIPANAVIAVDECTGAMSRAAATLFPRGAPVDAAAIVGAAKA 145 + ++ E + A+ +AD + V+E A + L + + D AI A + Sbjct: 359 LTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDVLNKKFSKADRDAIFNALAS 418 Query: 146 VKTPD---ELSCIRTAIRITDEAM 166 VK D L ++IT Sbjct: 419 VKYDDWAKHLDQFAKYLKITGHVS 442
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 109 bits (273), Expect = 8e-31 Identities = 77/252 (30%), Positives = 121/252 (48%), Gaps = 19/252 (7%) Query: 13 RVAVVTGAGAGIGRGIAAGLAAFGARVAIWERDAQTCTRAAESIGGLG-----IVTDVRD 67 ++A +TGA GIG +A LA+ GA +A + + + + S+ DVRD Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 68 SGQVDAALQRTITELGTPAILVNNAGGVFSSPLLETSENGWDALYRANLRHVLLCTQRIA 127 S +D R E+G ILVN AG + + S+ W+A + N V ++ ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 128 RQLVSVGAGGSIISLTSIEGVRAAPGYAAYAAAKAGVINYTKTAALELAPHGIRVNAIAP 187 + ++ GSI+++ S AAYA++KA + +TK LELA + IR N ++P Sbjct: 129 KYMMD-RRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 188 DITLTE----------GLEQ-LGGEAATTAMGNIVPLGRPGHVDEIASAAVFLASDMSGY 236 T T+ G EQ + G T G +PL + +IA A +FL S +G+ Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTG--IPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 237 LTGQTLHVDGGT 248 +T L VDGG Sbjct: 246 ITMHNLCVDGGA 257
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 83.9 bits (207), Expect = 3e-21 Identities = 46/191 (24%), Positives = 86/191 (45%), Gaps = 1/191 (0%) Query: 7 GFDGRAAVVTGGASGIGLATATEFARRGARLVLSDVDQPALEQAVNGLRGQGFDAHGVVC 66 G +G+ A +TG A GIG A A A +GA + D + LE+ V+ L+ + A Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 67 DVRHLDEMVRLADEAFRLLGGVDVVFSNAGIVVAGPLAQMNHDDWRWVIDIDLWGSIHAV 126 DVR + + R +G +D++ + AG++ G + ++ ++W ++ G +A Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 127 EAFLPRLLEQGTGGHIAFTASFAGLVPNAGLGTYGVAKYGVVGLAETLAREVKPNGIGVS 186 + ++++ G I S VP + Y +K V + L E+ I + Sbjct: 125 RSVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 187 VLCPMVVETKL 197 ++ P ET + Sbjct: 184 IVSPGSTETDM 194
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 103 bits (258), Expect = 2e-28 Identities = 81/285 (28%), Positives = 126/285 (44%), Gaps = 39/285 (13%) Query: 5 VEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETA 64 +EGK+AF+TGAA+G G + A LA +GA I AVD P + V +++ A A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVD-YNPEKLEKVVSSLKA-----EARHA 59 Query: 65 DLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEED 124 + DVRD A+ ++G +DI+V AG+ G + S+E+ Sbjct: 60 EAFP----------ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPG-LIHSLSDEE 108 Query: 125 WTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGL 184 W +N GV+ ++ +M+ R GSI+ S Y ++K V Sbjct: 109 WEATFSVNSTGVFNASRSVSKYMMD-RRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMF 167 Query: 185 MRAFGVDLGQHMIRVNSVHPTHVKTPM-----LHNEGTFKMFRPDLENPGPDDMAPICQM 239 + G++L ++ IR N V P +T M G ++ + LE Sbjct: 168 TKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLET------------ 215 Query: 240 FHTLPIPW---VEPIDISNAVLFFASDEARYITGVTLPIDAGSCL 281 IP +P DI++AVLF S +A +IT L +D G+ L Sbjct: 216 -FKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 54.6 bits (131), Expect = 2e-11 Identities = 28/164 (17%), Positives = 61/164 (37%), Gaps = 5/164 (3%) Query: 20 KTAKLRAAQRVQRFLDAAQAIIIEKGSTDFTVQEVVDRSRQSLRSFYLQFDGKHELLLAL 79 + K A + Q LD A + ++G + ++ E+ + + + Y F K +L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 80 FEDALSRSADQIRAATES-HTDPLERLQVAVQLLYEASRPDPTAKRPLFTDFAPRLLVTH 138 +E + S + DPL L+ + + E++ + + + F V Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 139 PAEV----KVAHAPLLALLTELMEAAGEAGKLRTTINPKRVAAM 178 A V + + + ++ EA L + +R A + Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAII 166
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 29.3 bits (65), Expect = 0.022 Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 8/47 (17%) Query: 248 DVQPLASDAPAA---PAVEPYRDPAYDPADVSSGALTKPRTSADPEP 291 D+ P +++AP A P V P +PA +PA + P T +PEP Sbjct: 314 DLTPGSAEAPNAQPLPEVSPAENPANNPAPNEN-----PGTRPNPEP 355
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 34.0 bits (78), Expect = 0.003 Identities = 47/243 (19%), Positives = 77/243 (31%), Gaps = 59/243 (24%) Query: 776 TVLLTGATGFLGRYLALEWLERMDMV-------DGKVIALVRARSDEEARARLDKTFDSG 828 L+TGA GF+G +++ LE V D ++L +AR E A+ F Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARL--ELLAQPGFQFHKI 59 Query: 829 D----PKLLAHYQQLAADHLEVIAGDKGEANLGLGQDVWQRLADTVDVIVDPAALVNHVL 884 D + + + + + R + + +P A + Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLA-----------VRYS-----LENPHAYAD--- 100 Query: 885 PYSELFGPNALGTAELIRLALTSKQKPYTYVSTIGVGDQIEPGKFVENADIRQMSATRAI 944 N G ++ +K + Y S+ V F + + Sbjct: 101 -------SNLTGFLNILEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHP------ 147 Query: 945 NDSYANGYGNSKWAGEVLLREAHDLCGLPVAVFRCDMILADTTYAGQLNLPDM----FTR 1000 + Y +K A E++ L GLP R T Y G PDM FT+ Sbjct: 148 ----VSLYAATKKANELMAHTYSHLYGLPATGLR-----FFTVY-GPWGRPDMALFKFTK 197 Query: 1001 LML 1003 ML Sbjct: 198 AML 200
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 62.9 bits (153), Expect = 7e-13 Identities = 40/215 (18%), Positives = 78/215 (36%), Gaps = 22/215 (10%) Query: 367 RTQISGGDPPFTAATAKQLAN----VLKYGSLPLSFQSSEAQTVSATLGLTSLRAGLIAG 422 + Q G A ++L N L L S E +V + + + + Sbjct: 102 QMQEDGQGAEGQGAQGQELVNKVETALTAVDPALKITSFE--SVGPKVSGELVWTAVWSL 159 Query: 423 AIGLLLVLLYSLLYYRVLGLLTALSLAASGAMVFAILILLGRYI--NYTLDLAGIAGLII 480 ++++ Y + + +L A A+V +L+ +G + DL +A L+ Sbjct: 160 LAATVVIMFYIWVRFEWQ-----FALGAVVALVHDVLLTVGLFAVLQLKFDLTTVAALLT 214 Query: 481 GIGTTADSFVVFFERIKDEIR--EGRTFRSAVPRGWTRARKTIVSGNAVTFLAAAVLYFL 538 G + + VV F+R+++ + + R + V T LA + Sbjct: 215 ITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETLSRTVMTGMTTLLALVPMLIW 274 Query: 539 AIGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLAS 573 ++GF F + + VF T+ VY+A Sbjct: 275 GGDVIRGFVFAM-------VWGVFTGTYSSVYVAK 302 Score = 36.0 bits (83), Expect = 4e-04 Identities = 18/99 (18%), Positives = 35/99 (35%), Gaps = 7/99 (7%) Query: 14 LSVFLLLLVGVYLLVFLTGDKRAAPKLGIDLQGGTRVTLTARTPDGSAPSREALAQAQQI 73 +++++ +L + G GID +GGT + + T R AL + ++ Sbjct: 24 FGAAIVMMIASVILPLVIG-----LNFGIDFKGGTTIRTESTTAIDVGVYRAAL-EPLEL 77 Query: 74 ISARVNGLGVSGSEVVVDGDNLIITVPGNDGNEARNLGQ 112 ++ + S +I DG A G Sbjct: 78 GDVIISEVR-DPSFREDQHVAMIRIQMQEDGQGAEGQGA 115
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 248 bits (636), Expect = 1e-81 Identities = 66/310 (21%), Positives = 139/310 (44%), Gaps = 16/310 (5%) Query: 52 FEVVGRRRLWFGISGAIVAVAILSIALRGFTFGIDFNGGTTVSMPAAGT------HGTVH 105 F+ + FG + ++ +++ + G FGIDF GGTT+ + + Sbjct: 14 FDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRAALE 73 Query: 106 TAQVQEVFRKTLGTDPESVVVVGNGAAATVQIRSETLTNDQTTKLRNALFDAFGPKGADG 165 ++ +V + S + A +Q++ + + L + Sbjct: 74 PLELGDVIISEVRD--PSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAV 131 Query: 166 KPSKQAISDSQVSETWGDQITDKALIALVVFLALVGLYITVRYERYMTLAAIAAMFFDLT 225 P+ + S V ++ A+ +L+ ++ YI VR+E L A+ A+ D+ Sbjct: 132 DPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVL 191 Query: 226 VTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTRDFQHTNRRTFAEQANL 285 +T G+++++ + TV LLTI G+S+ DTV+VFD++ EN ++ + NL Sbjct: 192 LTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTM---PLRDVMNL 248 Query: 286 AINQTFMRSINTSLIGVLPVLALMVVAVWLLGVGTLKDLALVQLVGILVGTYSSIFVATP 345 ++N+T R++ T + +L ++ +++ G ++ + G+ GTYSS++VA Sbjct: 249 SVNETLSRTVMTGMTTLLALVPMLI-----WGGDVIRGFVFAMVWGVFTGTYSSVYVAKN 303 Query: 346 LLVTLRERTE 355 +++ + Sbjct: 304 IVLFIGLDRN 313
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 34.3 bits (78), Expect = 0.001 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 8/82 (9%) Query: 128 RAGLIHRDVKPMNVLVTTARDFVYLIDFGLARAQADTALTQTGATMGTVAYMAPERFTGT 187 +AG++H D+KP NV+ A +ID GL + T ++ APE G Sbjct: 263 KAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQ------PKGFTESFKAPELGVGN 316 Query: 188 --TDHRADVYSLACVLHECLTG 207 ++DV+ + L C+ G Sbjct: 317 LGASEKSDVFLVVSTLLHCIEG 338
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 28.1 bits (62), Expect = 0.046 Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 10/80 (12%) Query: 45 RTRRILLIAAGSIVAVAVIAAVVVTVLNNRNEHKASTAAPSTSTSAPETTTPGQPSQVPP 104 + RI+ AA +++AVA IAA + V + A+T ++ +A V Sbjct: 3 KNLRIVSAAAAALLAVAPIAATAMPV------NAATTINADSAINANTNA----KYDVDV 52 Query: 105 LPPFKPSADVGANCQYPPSP 124 P A V + P P Sbjct: 53 TPSISAIAAVAKSDTMPAIP 72
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 29.5 bits (66), Expect = 0.027 Identities = 15/53 (28%), Positives = 25/53 (47%), Gaps = 2/53 (3%) Query: 82 ARDRVLSARGLDVLLTDLEKQQALMAEVADDDARDRAIRRYGQLEERFVALGG 134 D ++ GLD L D E+ + M +AD + R GQ ++ ++ GG Sbjct: 220 DNDMAVALNGLD--LRDAEQAKKAMERMADVHNFTLTVERDGQRQDIYMEFGG 270
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.0 bits (163), Expect = 4e-16 Identities = 33/177 (18%), Positives = 62/177 (35%), Gaps = 14/177 (7%) Query: 1 MPKVSEDHLAARRRQILDGARRCFAEFGYDKATVRRLEQAIGMSRGAIFHHFRDKDALFF 60 M + ++ R+ ILD A R F++ G ++ + +A G++RGAI+ HF+DK LF Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 ALAHEDAERMAEVAS--------------RAGLIQVMRDMLAAPDQFDWLATRLEIARKL 106 + + E+ R LI V+ + + + + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 107 RNDPAFSRGWAERSAELAAATTDRLRRQTEAHRVRDDVPGDVLQCYLELVLDGLVAR 163 + E L+ EA + D+ + + GL+ Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMEN 177
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 39.3 bits (91), Expect = 3e-05 Identities = 36/214 (16%), Positives = 66/214 (30%), Gaps = 24/214 (11%) Query: 45 NLAALIANVAKANQRLQNLSAEIQTEQESVNKALVDVE----TARDNAAAAQHDLEASQQ 100 + + L+ A ++ Q + KAL + + A Sbjct: 166 GAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAA 225 Query: 101 AVKDANAAIAGAQRRFDTFAAAAYMNGPSNSYLTARNPD----------DIIATEAAAKT 150 D A+ GA +A + L AR + A A KT Sbjct: 226 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKT 285 Query: 151 LTASSQTVMAKLQQARTE----QVNRESAAR-LAKQNADKAAADAKASQ-----DAAVAA 200 L A + A+ + NR+S R L K +A+ + + A+ Sbjct: 286 LEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEAS 345 Query: 201 LTNSRQKFDEQREQMIRLATERDQAQAKLEAAKR 234 + R+ D RE +L E + + + + ++ Sbjct: 346 RQSLRRDLDASREAKKQLEAEHQKLEEQNKISEA 379 Score = 38.9 bits (90), Expect = 3e-05 Identities = 34/205 (16%), Positives = 65/205 (31%), Gaps = 37/205 (18%) Query: 37 AQADPVADNLAALIANVAKANQRLQNLSAEIQTEQESVNKALVDVETARDNAAAAQHDLE 96 + + + L A A R L ++ ++T AA + + Sbjct: 239 NFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKA 298 Query: 97 ASQQAVKDANAAIAGAQRRFDTFAAAAYMNGPSNSYLTARNPDDIIATEAAAKTLTASSQ 156 + + NA +R D A+ A K L A Q Sbjct: 299 DLEHQSQVLNANRQSLRRDLD-------------------------ASREAKKQLEAEHQ 333 Query: 157 TVMAKLQQARTEQVNRESAARLAKQNADKAAADAKASQDAAVAALTNSRQKFDEQREQMI 216 + + + + A+R + + A+ +AK +A L + + R+ + Sbjct: 334 KLEEQNKISE--------ASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLR 385 Query: 217 R-LATERD---QAQAKLEAAKRQLS 237 R L R+ Q + LE A +L+ Sbjct: 386 RDLDASREAKKQVEKALEEANSKLA 410
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.4 bits (79), Expect = 6e-04 Identities = 32/162 (19%), Positives = 60/162 (37%), Gaps = 21/162 (12%) Query: 41 AEVQTLERAIFEVKRIIVGQD----QLVERMLVGLLSKGHVLLEGVPGVAKTL---AVET 93 LE + ++ G+ ++ + + + +++ G G K L A+ Sbjct: 124 RRPSKLEDDSQDGMPLV-GRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD 182 Query: 94 FAKVVGGTFARIQ---FTPDLVPTDIIG------TRIYRQGKEEFDTELGPVVVNFLLAD 144 + K G F I DL+ +++ G T + F+ G L D Sbjct: 183 YGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGT----LFLD 238 Query: 145 EINRAPAKVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQN 186 EI P Q+ LL V+Q+ + G P+ + ++A N Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATN 280
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 112 bits (280), Expect = 6e-32 Identities = 65/252 (25%), Positives = 122/252 (48%), Gaps = 21/252 (8%) Query: 24 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPDGLFGVE-----------CDVTD 72 + +TG +GIG A+A+ LA+ G +A + + DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 73 NDAVDRAFTEVEEHQGPVEVLVSNAGISKDAFLIRMTEERFTEVINANLTGAFRVTQRAA 132 + A+D +E GP+++LV+ AG+ + + +++E + + N TG F ++ + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 133 RSMQKKRFGRIIYIGSVSGMWGIGNQSNYAAAKAGLIGMARSISRELSKAGVTANVVAPG 192 + M +R G I+ +GS + + YA++KA + + + EL++ + N+V+PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 193 YIDTEMTRAL-------DERIQAGALEF---IPAKRVGTAAEVAGAVSFLASEDASYIAG 242 +T+M +L ++ I+ F IP K++ +++A AV FL S A +I Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 243 AVIPVDGGMGMG 254 + VDGG +G Sbjct: 249 HNLCVDGGATLG 260
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 57.0 bits (137), Expect = 9e-12 Identities = 53/274 (19%), Positives = 102/274 (37%), Gaps = 34/274 (12%) Query: 5 LDGKRILVTGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIVD-------RLPEK 57 ++GK +TG I +A+ GA + D V R E Sbjct: 6 IEGKIAFITG--AAQGIGEAVARTLASQGAHI--AAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 58 APLIELDVQNEEHLNTLAQRVTAEIGEGNRLDGVVHSIGFMPQTGMGINPFFDAPYEDVS 117 P DV++ ++ + R+ E+G +D +V+ G + E+ Sbjct: 62 FPA---DVRDSAAIDEITARIEREMG---PIDILVNVAGVLR-----PGLIHSLSDEEWE 110 Query: 118 KGIHISAYSYASLAKALLPIM--NPGGSIVGMDFD----PSRAMPAYNWMTVAKSALESV 171 +++ + ++++ M GSIV + + P +M AY +K+A Sbjct: 111 ATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYA---SSKAAAVMF 167 Query: 172 NRFVAREAGPHGVRSNLVAAGPIRTLAMAGIVGGVLGDQAAEQIRLLEEGWDQRAPIGWN 231 + + E + +R N+V+ G T + + A + I+ E + P+ Sbjct: 168 TKCLGLELAEYNIRCNIVSPGSTETDMQWSL--WADENGAEQVIKGSLETFKTGIPLK-K 224 Query: 232 MKDPTPVAKTVCALLSDWLPATTGTIIYADGGAS 265 + P+ +A V L+S T + DGGA+ Sbjct: 225 LAKPSDIADAVLFLVSGQAGHITMHNLCVDGGAT 258
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.3 bits (63), Expect = 0.044 Identities = 33/142 (23%), Positives = 50/142 (35%), Gaps = 15/142 (10%) Query: 185 LGDAEYTLRSAVRSAAETLGAIGLGS---AASDVDDPRGLVEQLLESARQHRIPDHAPSR 241 L A Y +R +AA I G +DV P LL ++ R PD Sbjct: 23 LSRAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKAR-PD----- 75 Query: 242 ALRVLENAAHVDAIIAVSAGLSRSDS--PDRFAAPIAAGLE--PLGTQSSSEARIAGDAL 297 L VL +A + A+ A + P F G+ L +++ D+ Sbjct: 76 -LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQ 134 Query: 298 RPLTAVVRSARMAAVTAILHSA 319 + V RSA M + +L Sbjct: 135 DGMPLVGRSAAMQEIYRVLARL 156
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 32.6 bits (74), Expect = 0.005 Identities = 19/121 (15%), Positives = 33/121 (27%), Gaps = 10/121 (8%) Query: 110 HPGRPRPSHDSGPPTLTWTAITEQTNPTRPTRRPVPPRRPARPP---STPPEERTVIVPG 166 P P+ P ++T A + P P P P P PP+E V++ Sbjct: 40 VIELPAPAQ---PISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEK 96 Query: 167 SPARSRVAPASAPAGPPRTSPTPATEFTVIDAKTADVSNLATRFVKLLSPRASSAAGTAG 226 + + P E + N A + A+++ Sbjct: 97 PKPKPKPKPKPVKKVEQPKRDVKPVE----SRPASPFENTAPARPTSSTATAATSKPVTS 152 Query: 227 A 227 Sbjct: 153 V 153 Score = 30.3 bits (68), Expect = 0.026 Identities = 25/140 (17%), Positives = 40/140 (28%), Gaps = 5/140 (3%) Query: 104 QQGHAGHPGRPRPSHDSGPPTLTWTAITEQTNPTRPTRRPVPPRRPARPPSTPPEERTVI 163 + A P P P + P ++ +P P +P +R Sbjct: 61 EPPQAVQP-PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKR--- 116 Query: 164 VPGSPARSRVAPASAPAGPPRTSPTPATEFTVIDAKTADVSNLATRFVKLLSPRASSAAG 223 P SR A P R + + AT T + A + P + A Sbjct: 117 -DVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALR 175 Query: 224 TAGAMTIGRAADNDIVVADV 243 G + + D V +V Sbjct: 176 IEGQVKVKFDVTPDGRVDNV 195
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 31.6 bits (71), Expect = 0.010 Identities = 48/213 (22%), Positives = 87/213 (40%), Gaps = 46/213 (21%) Query: 69 HPHIVGVH--------DRGEFNGHLWISMDYVEG---TDASRLVKESYPDGMPLDE---- 113 HP++ VH +R E + MD V+G +D R + +S+ G E Sbjct: 190 HPNLANVHGMAVVPYGNRKEEA----LLMDEVDGWRCSDTLRTLADSWKQGKINSEAYWG 245 Query: 114 -VSAIVQAVAGALDYAHARGLLHRDVKPANILLTHPEAGERRILLADFGVARHLGD-ISG 171 + I + ++ G++H D+KP N++ +GE ++ D G+ G+ G Sbjct: 246 TIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRA-SGEPVVI--DLGLHSRSGEQPKG 302 Query: 172 ITETNVAVGTVAYAAPEQLTGS-PIDGRADQYALAATAFHLLTGAPPFQHSNPIAVIGQH 230 TE+ + APE G+ ++D + + +T H + G NP Q Sbjct: 303 FTES--------FKAPELGVGNLGASEKSDVFLVVSTLLHCIEGF----EKNPEIKPNQG 350 Query: 231 LH---EDPPRLSD------FRPELAGLDEVFCQ 254 L +P + D RP +AG++ + + Sbjct: 351 LRFITSEPAHVMDENGYPIHRPGIAGVETAYTR 383
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 33.3 bits (76), Expect = 0.003 Identities = 22/100 (22%), Positives = 36/100 (36%), Gaps = 8/100 (8%) Query: 206 VQYTRNDLS-FTRGSFRVRGDTVEIIPSYEELAVRIEFFGDEIEALYYLHPLTGDVIRQV 264 + T LS R V +V+ + YEE I A+ + PL G+ + +V Sbjct: 63 ARLTTTSLSAQLRSMVHVHVASVDQLT-YEEFIRSIPTPS--TLAVITMDPLKGNAVLEV 119 Query: 265 DSLRIFPATHYVAGPERMAHAI----STIEQELAERLAEL 300 D F + G A + + IE + E + Sbjct: 120 DPSITFSIIDRLFGGTGQAAKVQRDLTDIENSVMEGVIVR 159
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 36.0 bits (83), Expect = 2e-04 Identities = 48/311 (15%), Positives = 108/311 (34%), Gaps = 21/311 (6%) Query: 1 MQGVAGGLLAGLGYAVINSALPRWLWTRGSALVSAMWGVATVVGPATGGLFAQLGIWRWA 60 +QG L V+ +P+ + L+ ++ + VGPA GG+ A W + Sbjct: 112 IQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYL 171 Query: 61 FVVM--AVLTALMALLVPVALARVDPAPAIPRMKVPVWSLLIIGVAALAVSVAQIPHNTA 118 ++ ++T + + R+ I + L+ +G+ + T+ Sbjct: 172 LLIPMITIITVPFLMKLLKKEVRIKGHFDIKGI-----ILMSVGIVFFMLFT------TS 220 Query: 119 ATFGLLAAGIMLVGLFVIVDWRMHAAILPPSVFSPGP-LKWIYLTMGVLMAAAMVNTYVP 177 + L ++ +FV ++ + P + P + + + A + VP Sbjct: 221 YSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVP 280 Query: 178 LFGQRLAHLTPIAAGFLGAALALGWTVSEIVSASLENPRTVGRVVMVAPLVAASGLALGA 237 + + L+ G+ + T+S I+ + V R + V G+ + Sbjct: 281 YMMKDVHQLSTAEI---GSVIIFPGTMSVIIFGYIGG-ILVDRRGPL--YVLNIGVTFLS 334 Query: 238 VARHGDGSAWTAALWAVALLVAGTGIGMAWPHLSARAMASVN-DPAEGGAASAAINTVQL 296 V+ W + +++ G+++ + S + E GA + +N Sbjct: 335 VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSF 394 Query: 297 TSAAIGAGLAG 307 S G + G Sbjct: 395 LSEGTGIAIVG 405
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 70.5 bits (172), Expect = 2e-16 Identities = 63/263 (23%), Positives = 114/263 (43%), Gaps = 12/263 (4%) Query: 4 LSGKKAVVTGAGGDGLGQAIANRLGGLGADIALIGRTLEKVQRRGREVEERWGVKTVAIS 63 + GK A +TGA G+G+A+A L GA IA + EK + + A Sbjct: 6 IEGKIAFITGAA-QGIGEAVARTLASQGAHIAAVDYNPEK-LEKVVSSLKAEARHAEAFP 63 Query: 64 ADMSDWDQVHNAVREAHWQLGGLDIMVNNPVMVAGGLFETQTKEQIDFTVLGSLSMMMYG 123 AD+ D + ++G +DI+VN ++ GL + + E+ + T S+ G Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEAT----FSVNSTG 119 Query: 124 AHAALQ----FLLPQGSGKIINIGSVGGRIQQRGLVVYNACKAGVIGFTRNLAHEVALRG 179 A + +++ + SG I+ +GS + + + Y + KA + FT+ L E+A Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 180 VNVLGVAPGIMLNPQLKQYVLDPQDDQERAGRAAIIEAITQQVQLGRASLPEEAANMVAF 239 + V+PG Q+ L ++ +E + L + + P + A+ V F Sbjct: 180 IRCNIVSPGSTETDM--QWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLF 237 Query: 240 LATEAADYLCGQTIDVAGGQWMG 262 L + A ++ + V GG +G Sbjct: 238 LVSGQAGHITMHNLCVDGGATLG 260
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 110 bits (277), Expect = 3e-31 Identities = 80/264 (30%), Positives = 115/264 (43%), Gaps = 14/264 (5%) Query: 3 DNKVALITGAARGQGRAHAVRLSAGGADIIAVDIAGRLPESVPYESPTRDDLAETARLVE 62 + K+A ITGAA+G G A A L++ GA I AVD E V ++ Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKV-------------VSSLK 53 Query: 63 ANGRRAITAAIDVRDAEKLSAAVGHAVAELGRLDIIVANAGICCPAPWDQITGQAFRDTI 122 A R A DVRD+ + E+G +DI+V AG+ P ++ + + T Sbjct: 54 AEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATF 113 Query: 123 DTNVIGTWNTVMAGAHHIIAGRRGGSIILIGSAAGVKMQAFMVHYTASKHAITGMARAFA 182 N G +N + RR GSI+ +GS + M Y +SK A + Sbjct: 114 SVNSTGVFN-ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLG 172 Query: 183 AELGRYNIRVNSLHPGAVDTPMGTGRMRDALESAAATYPHLEGLHKPLLPDGIAQPEDIA 242 EL YNIR N + PG+ +T M D + LE + +A+P DIA Sbjct: 173 LELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIA 232 Query: 243 DAVAWLASDQSRFVTASGISVDLG 266 DAV +L S Q+ +T + VD G Sbjct: 233 DAVLFLVSGQAGHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 92.4 bits (229), Expect = 2e-24 Identities = 74/266 (27%), Positives = 114/266 (42%), Gaps = 27/266 (10%) Query: 2 RGLQGKTFIVAGGSTGIGAATAERLASEGAAVTVGDINIEGANATVGRITQSGGRAIAVE 61 +G++GK + G + GIG A A LAS+GA + D N E V + A A Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 62 FDLADEASVRNLVQKTIGEFGALHGLHNVGSDLSAENLGRDTTLLDTDFDVWRRTLDVNL 121 D+ D A++ + + E G + L NV L G +L D + W T VN Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVL---RPGLIHSLSDEE---WEATFSVNS 117 Query: 122 LGYVRTSRAVLAHLLQQGSGSIVNTSSGGSLGTDPMHV------AYNAAKAAVNQLTRHI 175 G SR+V +++ + SGSIV ++G++P V AY ++KAA T+ + Sbjct: 118 TGVFNASRSVSKYMMDRRSGSIV------TVGSNPAGVPRTSMAAYASSKAAAVMFTKCL 171 Query: 176 ANNWGAQGVRCNGVMPGLVMGETQKQ---QNDIQLQ------QMFLQAAKVTRLGEPRDI 226 +RCN V PG + Q + Q + F + +L +P DI Sbjct: 172 GLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDI 231 Query: 227 AAITAFLLSDEAEWINGQVWYIGGAS 252 A FL+S +A I + G + Sbjct: 232 ADAVLFLVSGQAGHITMHNLCVDGGA 257
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 73.2 bits (179), Expect = 4e-17 Identities = 54/176 (30%), Positives = 78/176 (44%) Query: 6 QTVVITGASAGIGRATAKEFGRRGANVALLARGAAGLQGAARDVEAGGGKALALPTDVAD 65 + ITGA+ GIG A A+ +GA++A + L+ ++A A A P DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 66 HAAVVAAADETEAAFGPIDVWVNVAFTSVFAPFSEISAEEFKRVTEVTYLGYVHGTMAAL 125 AA+ E GPID+ VNVA +S EE++ V G + + + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 126 AKMRPRDRGTIVQVGSALSQRSIPLQSAYCGAKHAVNGFTESVRCELLHEGSRVRI 181 M R G+IV VGS + +AY +K A FT+ + EL R I Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 76.2 bits (187), Expect = 2e-18 Identities = 61/214 (28%), Positives = 91/214 (42%), Gaps = 36/214 (16%) Query: 5 LSGKTALVTGSSRGIGRAVAQRLAAAGATVAVTARSHS------SSLSTRAGTATALPGT 58 + GK A +TG+++GIG AVA+ LA+ GA +A + SSL A A A P Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP-- 63 Query: 59 IGETIELIEAAGGSAFGIAADLEDADQRDGLVDAVLDRTGRIDILVNNAGFADYSLVEDM 118 AD+ D+ D + + G IDILVN AG L+ + Sbjct: 64 -------------------ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSL 104 Query: 119 SLETFDRTVEHYLRVPFVLTKCAVPHMRKQGAGWIVNIGSVTGVAPVRPYREYNKASGDV 178 S E ++ T F ++ +M + +G IV +GS P + Sbjct: 105 SDEEWEATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVP---------RTSMA 155 Query: 179 VYAAMKAALHRFTQGVAAELLDASIAVNCVGPST 212 YA+ KAA FT+ + EL + +I N V P + Sbjct: 156 AYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 123 bits (309), Expect = 4e-36 Identities = 78/263 (29%), Positives = 121/263 (46%), Gaps = 13/263 (4%) Query: 3 GLSGRVVLVTGAGRGIGRSHCQRFAEEGADVIAVDVPAAAPDLAQTAAAVQQRGVRAATA 62 G+ G++ +TGA +GIG + + A +GA + AVD + ++ + R A A Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 63 LADVSDFAALAAAVDEAVGRLGRLDVLVGNAGI-HPAAAPAWEITPQNWQQTLDVNLTGV 121 DV D AA+ +G +D+LV AG+ P ++ + W+ T VN TGV Sbjct: 65 --DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPG--LIHSLSDEEWEATFSVNSTGV 120 Query: 122 WHTVKAGVPHMSRTARGGSIVIISSTSGIRGTPGAAPYSASKHAVVGLARTLANELGPQG 181 ++ + V R GSIV + S A Y++SK A V + L EL Sbjct: 121 FNASR-SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 182 IRVNTVHPGAVATAMVLNEATFRRLRPDLDNATADDAAEALSARHLLPVPWV-EPVDVSN 240 IR N V PG+ T M L D + A + + +P+ + +P D+++ Sbjct: 180 IRCNIVSPGSTETDMQ------WSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIAD 233 Query: 241 AVVFLASDQARYITGTQIVVDAG 263 AV+FL S QA +IT + VD G Sbjct: 234 AVLFLVSGQAGHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 113 bits (284), Expect = 3e-32 Identities = 80/277 (28%), Positives = 121/277 (43%), Gaps = 24/277 (8%) Query: 7 AGRLAGKVALITGAARGIGRAQAVRFAQEGADIVALDLCGPVDTVMVPPSTPDDLDHTAS 66 A + GK+A ITGAA+GIG A A A +GA I A+D P V S + H + Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVD-YNPEKLEKVVSSLKAEARHAEA 61 Query: 67 LVGEVGGRMHAELVDVRDLDGVQAATERGARRFGGLDVVCATAGITSRAMTVEMDESVWR 126 DVRD + T R R G +D++ AG+ + + + W Sbjct: 62 FP-----------ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWE 110 Query: 127 TMLDVNLTGVWHTCRAAAPHLIARGAGSMILTNSIAGLRGLVGVAHYTAAKHGVVGLMQS 186 VN TGV++ R+ + +++ R +GS++ S +A Y ++K V + Sbjct: 111 ATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKC 170 Query: 187 LAHELAPHRVRVNCVHPTNVDTPLIQNDTVRSAFRPDLDRPPTRAEFAEAARAMNLLQVP 246 L ELA + +R N V P + +T D S + + E + +P Sbjct: 171 LGLELAEYNIRCNIVSPGSTET-----DMQWSLWADENGAEQVIKGSLETFK----TGIP 221 Query: 247 W---VDPVDVANAALFLASDEARYITAVTLPVDAGAT 280 P D+A+A LFL S +A +IT L VD GAT Sbjct: 222 LKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGAT 258
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.3 bits (65), Expect = 0.022 Identities = 9/38 (23%), Positives = 15/38 (39%) Query: 261 QAQQDKAEAQREAAQKEAEAESARKAAEINEARQKAEQ 298 Q+ + E Q ++ A E KA E Q+ + Sbjct: 1087 QSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPK 1124
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 87.8 bits (217), Expect = 2e-23 Identities = 54/183 (29%), Positives = 86/183 (46%), Gaps = 11/183 (6%) Query: 1 MLDRYGRIDVLVNNVGHWLRHPGGFADTDPQLWDELYRINLHHVFLVTHAFLPTMIDRGA 60 + G ID+LVN G + PG + W+ + +N VF + + M+DR + Sbjct: 79 IEREMGPIDILVNVAG--VLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYMMDRRS 136 Query: 61 GAIVNVSSVEGLRGYPEDPVYAAFKAAVIGFTRSLAVQVGNHGVRVNAVAPDVTESLQVP 120 G+IV V S YA+ KAA + FT+ L +++ + +R N V+P TE+ + Sbjct: 137 GSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTET-DMQ 195 Query: 121 YSQWLS--AEEQ------SQWPRWVPVGRMGLPEDQARVILFLASDCSSFITGHTIPTDG 172 +S W EQ + +P+ ++ P D A +LFL S + IT H + DG Sbjct: 196 WSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDG 255 Query: 173 GTT 175 G T Sbjct: 256 GAT 258
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 69.3 bits (169), Expect = 8e-16 Identities = 53/205 (25%), Positives = 92/205 (44%), Gaps = 17/205 (8%) Query: 13 LRGKFAVVTGANSGLGFGLAKRLAAAGAEVVLAVRDPAKGDQAVAAIRREVPQAKLTIRQ 72 + GK A +TGA G+G +A+ LA+ GA + +P K ++ V++++ E A+ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF--P 63 Query: 73 LDLSSLRSVAALGEQLTAEGRPIDILINNAGVMAP-PRRQQTSDGFELQFGTNHLGHFAL 131 D+ ++ + ++ E PIDIL+N AGV+ P + + +E F N G F Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 132 TGRLLALLRAADSARVVTVSSIAATQRKLDFADVNAEHGYQPMYSYGVAKLAQLMFAVEL 191 + + + S +VTV S A + M +Y +K A +MF L Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTS------------MAAYASSKAAAVMFTKCL 171 Query: 192 DRRSRLGGWGLMSNAAHPGLAKTNL 216 L + + N PG +T++ Sbjct: 172 GL--ELAEYNIRCNIVSPGSTETDM 194
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 47.3 bits (112), Expect = 1e-08 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 1/83 (1%) Query: 8 RSDRSTGTREAILSAAEVLFAERGMYAVSNRQISEAAGQGNNAAACYHFGTRVDLLRAIE 67 + TR+ IL A LF+++G+ + S +I++AAG A +HF + DL I Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGV-TRGAIYWHFKDKSDLFSEIW 63 Query: 68 GKHREPIEKLRAQMLAAVGDSTE 90 I +L + A Sbjct: 64 ELSESNIGELELEYQAKFPGDPL 86
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 31.9 bits (72), Expect = 7e-04 Identities = 14/50 (28%), Positives = 25/50 (50%), Gaps = 1/50 (2%) Query: 34 VRITVSGRKTGLARSATVQYVPFRDGLLLVGSNWGRRRHPSWSANLKAAQ 83 VRI + G++ A ++ V + F+D + G WG+ + WS L + Sbjct: 232 VRIVIEGKQYIKAEASIVNSLDFKDD-VSKGDLWGKENYSDWSNKLTPNE 280
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 83.9 bits (207), Expect = 5e-21 Identities = 65/253 (25%), Positives = 113/253 (44%), Gaps = 5/253 (1%) Query: 11 LSGRGAVVSGGSRGIGRAVAELLAGLGAGVVVNGRDPQAVQETVAAITAAGGRATAVVGA 70 + G+ A ++G ++GIG AVA LA GA + +P+ +++ V+++ A A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 71 ADDERIARSLVDECIGAFGRLDALINCAGIAEPAGSSILNITADEFDHLIGAHLGTAFHT 130 D + G +D L+N AG+ P I +++ +E++ + F+ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPG--LIHSLSDEEWEATFSVNSTGVFNA 123 Query: 131 CRAAAPVMVEQRHGSIVNT-SSVAFLGDYGGTGYPAGKGAVNALTMAIAAELKAYGVRAN 189 R+ + M+++R GSIV S+ A + Y + K A T + EL Y +R N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 190 VVCPGA-RTRLSTGADYERHIEDLHRRGLLDDMTRQASLDS-APPVFVAPVYGYLVSDLA 247 +V PG+ T + + + + +G L+ L A P +A +LVS A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 248 RDVTGQILVAAGG 260 +T L GG Sbjct: 244 GHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.4 bits (120), Expect = 7e-10 Identities = 26/135 (19%), Positives = 51/135 (37%), Gaps = 9/135 (6%) Query: 7 AGNTPASDAEAIERILDAADRIIAERG-SALRIADVARALGVTRQTVYRYFPGTQALLVA 65 A T E + ILD A R+ +++G S+ + ++A+A GVTR +Y +F L Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 66 SAMRSADGFLDRMAAHLDGVTDPVVAITEGMAFAVEELACDHQVEFVLNQRHRGGQKVSI 125 + +++ + A G +V H +E + + R I Sbjct: 62 --------IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEII 113 Query: 126 ISDTALAFGRSMLHR 140 +++ + Sbjct: 114 FHKCEFVGEMAVVQQ 128
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 54.7 bits (132), Expect = 7e-10 Identities = 35/97 (36%), Positives = 47/97 (48%), Gaps = 16/97 (16%) Query: 13 DTVITNGRWFDGTGGPSAMRDIGVRDGRVVTIA-AGPLDT---------AGATVIDASGQ 62 DTVITN D G A DIG++DGR+ I AG D G VI G+ Sbjct: 69 DTVITNALILDHWGIVKA--DIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGK 126 Query: 63 WVIPGIIDIHTHYDVEILCEPELSESLRHGVTTVLLG 99 V G +D H H+ +C ++ E+L G+T +L G Sbjct: 127 IVTAGGMDSHIHF----ICPQQIEEALMSGLTCMLGG 159
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 51.9 bits (124), Expect = 1e-10 Identities = 15/69 (21%), Positives = 35/69 (50%) Query: 16 ARRSDRRPGQTIRKVLDAGLQELRESSYAGLTMRAVATRAGVSPASAYTYFPSKSALVAA 75 AR++ + +T + +LD L+ + + ++ +A AGV+ + Y +F KS L + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 76 VYLRFLRDL 84 ++ ++ Sbjct: 62 IWELSESNI 70
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 39.3 bits (91), Expect = 3e-05 Identities = 43/150 (28%), Positives = 60/150 (40%), Gaps = 14/150 (9%) Query: 336 AGSARVLVATDIAARGVHVDEV--------ELVVHIDPPSEHKSYLHRSGRTARAGSAGD 387 AG +VL +A G+ V +LVV D +H+ ++ SG + SA Sbjct: 467 AGRFKVLTVNTLAGSGLFRMNVFADLGLSDKLVVMQDASGQHRLWVRNSG--SEPASANT 524 Query: 388 VVTVVLPEQREHTRALMRKAG-IDVAPQR--VTAGSQAVHALVGPIAPPKP-PAAAGVPS 443 ++ V P T L K G +D+ R + A +LVG APP P PA P Sbjct: 525 LLLVQTPLGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQ 584 Query: 444 HPAGPHRPAAAGQRRRRSGRSARTTAAHAV 473 P P A + +GR A AV Sbjct: 585 PPQPPQPQPEAPAPQPPAGRELSAAANAAV 614
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 27.5 bits (61), Expect = 0.033 Identities = 13/41 (31%), Positives = 15/41 (36%), Gaps = 6/41 (14%) Query: 138 WQVKDYVAGLT------PDSSDEQFRAAAPTIPVFALTKAG 172 W V D P S+ FR AP + L KAG Sbjct: 492 WNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAG 532
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.0 bits (132), Expect = 2e-11 Identities = 18/159 (11%), Positives = 51/159 (32%), Gaps = 5/159 (3%) Query: 8 GKRQQSREQIEARIIELGRRQLVDRGAAGLSVRAIARDLGMVSSAVYRYVSSRDELLTLL 67 K +Q ++ I+++ R +G + S+ IA+ G+ A+Y + + +L + + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 68 LVDAYSDL----ADTVDRARETAGEQWSDDVIAIARATRRWAVEHPACWALLYGSPVPGY 123 + S++ + + + +I + +T + + G Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 124 HAPPERTVAAG-TRVVAALFDAVAAGITTGDIRLTNDPA 161 A ++ + + I + Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTR 161
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.015 Identities = 11/52 (21%), Positives = 24/52 (46%) Query: 456 LVITGRSGAGKTTLLRSLAELWPYASGTLCRPDGDNATMFLSQLPYVPLGTL 507 +V+ G G GK+TL+ +L L ++ G ++ ++ + L + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEM 650
>SECA#SecA protein signature. Length = 901 Score = 856 bits (2212), Expect = 0.0 Identities = 281/816 (34%), Positives = 395/816 (48%), Gaps = 119/816 (14%) Query: 18 RLLGASTEKNRSRSLTLVTDSSEYDDEAAGLTDEQLR-KAAGLLNLEDLAESED--IPQF 74 ++ G+ ++ R +V + + E L+DE+L+ K A + E + IP+ Sbjct: 8 KVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEA 67 Query: 75 LAIAREAAERATGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGAIAAAGYVLAGRHVH 134 A+ REA++R G+R FDVQLLG + + + EM TGEGKTL + A L G+ VH Sbjct: 68 FAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVH 127 Query: 135 VVTINDYLARRDAEWMGPLIEAMGLTVGWITAESSSEERRAAYGCDVTYASVNEIGFDVL 194 VVT+NDYLA+RDAE PL E +GLTVG + +R AY D+TY + NE GFD L Sbjct: 128 VVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYL 187 Query: 195 RDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRETPRLEII-KLVGEL- 252 RD + + V AL+DE DS+L+DEA PL+++G + + + K++ L Sbjct: 188 RDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLI 247 Query: 253 ----------EAGTDYDTDADSRNVHLTDVGARKVEKAL-------GGIDLYSEEHVGTT 295 + + D SR V+LT+ G +E+ L G LYS ++ Sbjct: 248 RQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANI-ML 306 Query: 296 LTEVNVALHAHVLLQRDVHYIVRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETT 355 + V AL AH L RDV YIV+D V +++ GR Q +RW DGL AVEAKEG++ Sbjct: 307 MHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQ 366 Query: 356 ETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYKLGVSPIPPNKPNIREDEADR 415 + L +IT Q Y + GMTGTA + YKL +P N+P IR+D D Sbjct: 367 NENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDL 426 Query: 416 VYITAAAKNDAIVEHIIEVHETGQPVLVGTRDVAESEELHERLLRRGVPAVVLNAKNDAE 475 VY+T A K AI+E I E GQPVLVGT + +SE + L + G+ VLNAK A Sbjct: 427 VYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHAN 486 Query: 476 EAQVIAEAGKFGVVTVSTQMAGRGTDIRLGGSDEA----------------------DHD 513 EA ++A+AG VT++T MAGRGTDI LGGS +A HD Sbjct: 487 EAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHD 546 Query: 514 RVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVVAA-NLDR---- 568 V E GGLH++GT RH + R+DNQLRGR+GRQGD GSS F+ S ED ++ DR Sbjct: 547 AVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGM 606 Query: 569 -NKLPMETDPETGDGRIVSPKAAGLLDHAQRVAEGRMLDVHANTWRYNQLIAQQRAIIVD 627 KL M+ I P + +AQR E R D+ Y+ + QR I Sbjct: 607 MRKLGMKPGE-----AIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYS 661 Query: 628 RRNTLLRTATAREEL-------------AELAPKRYRELADEIP---------------- 658 +RN LL + E + A + P+ E+ D Sbjct: 662 QRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIA 721 Query: 659 -------------------------EERLETIC---------RHIMLYHLDRGWADHLAY 684 +R E + + +ML LD W +HLA Sbjct: 722 EWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAA 781 Query: 685 LADIRESIHLRALGRQNPLDEFHRLAVDAFASLAAD 720 + +R+ IHLR +++P E+ R + FA++ Sbjct: 782 MDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLES 817
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 39.0 bits (90), Expect = 3e-05 Identities = 29/88 (32%), Positives = 33/88 (37%), Gaps = 4/88 (4%) Query: 37 SHADPEVPTPVPPSTATAPPAAPAPNGQPAPNAQPAPGAPAPNGQPAPAAPAPNDPNAAP 96 S + V V P P +A APN QP P PA P PAP PN P Sbjct: 299 SQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAEN---PANNPAPNENPGTRPNPEP 355 Query: 97 PPVGAPPNGAPPPPVDPNAPPPPPADPN 124 P P+ P P P PA P+ Sbjct: 356 DP-DLNPDANPDTDGQPGTRPDSPAVPD 382 Score = 34.3 bits (78), Expect = 7e-04 Identities = 28/78 (35%), Positives = 33/78 (42%), Gaps = 7/78 (8%) Query: 43 VPTP-VPPSTATAPPAAPAPNGQPAPNAQPAPGAPAPNGQPAPAAPAPNDPNAAP---PP 98 +P P + P +A AP A P P PA N PA PAPN P DP+ P P Sbjct: 310 IPRPDLTPGSAEAPNAQPLPEVSPAEN--PA-NNPAPNENPGTRPNPEPDPDLNPDANPD 366 Query: 99 VGAPPNGAPPPPVDPNAP 116 P P P P+ P Sbjct: 367 TDGQPGTRPDSPAVPDRP 384
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 25.9 bits (57), Expect = 0.034 Identities = 12/54 (22%), Positives = 20/54 (37%) Query: 40 RGSGAGILMDIVIGIVGALIGGFILSFFVNTAGGGLIFTFFTALLGSVILLWIV 93 RG G G+ + + I I T GG I +G +++ +V Sbjct: 184 RGIGNGMSILMFISIAATFPSALWAIKKQGTLAGGWIEFGTVIAVGLIMVALVV 237
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 28.7 bits (64), Expect = 0.030 Identities = 12/43 (27%), Positives = 20/43 (46%) Query: 27 IAVVVVVLVLTNLVAHFTTPWASIGTVPAAAVGLVILMRYRGL 69 I+ VVV L L L ++ P + + VP VG+++ Sbjct: 878 ISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQ 920 Score = 27.9 bits (62), Expect = 0.047 Identities = 38/157 (24%), Positives = 61/157 (38%), Gaps = 23/157 (14%) Query: 24 HLDIAVVVVVLVLTNLVAHFTTPWASIGTVPAAAVGLVILMRYRGLGWADLGLGRDHWKS 83 L A+++V LV+ + + VP +G ++ G L + Sbjct: 343 TLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMF------ 396 Query: 84 GVGYALAAVAVVAAVIAIGVLLPATRPMFMNN---RYAT------ISGAMIASMVVIPVQ 134 G LA +V AI V+ R M + + AT I GA++ +V+ Sbjct: 397 --GMVLAIGLLVDD--AIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSA- 451 Query: 135 TVIPEELAFRGVLHGALNRAWGFR-GVALAGSLLFGL 170 IP +AF G GA+ R + A+A S+L L Sbjct: 452 VFIP--MAFFGGSTGAIYRQFSITIVSAMALSVLVAL 486
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 92.0 bits (228), Expect = 3e-24 Identities = 68/236 (28%), Positives = 104/236 (44%), Gaps = 25/236 (10%) Query: 11 VRDKVVVITGGARGIGLATATALHKLGAKVAIGD-----IDEVRVKESGAALDLDVYGKL 65 + K+ ITG A+GIG A A L GA +A D +++V A + + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF-PA 64 Query: 66 DVTDPHSFSDFLDEVERQLGPIDVLVNNAGIMPLGRVVDESDAVTRRILDINVYGVILGS 125 DV D + + +ER++GPID+LVN AG++ G + SD +N GV S Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 126 KLALARMIPRGRGHVINVASLAGETYLAGAATYCASKHAVVGFTDAARIEYRRSGVTFSV 185 + M+ R G ++ V S A Y +SK A V FT +E + ++ Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 186 VKPTFVNTEL--------------IAGTS-----GAKGVRNAEPSDIADAIVKLVA 222 V P T++ I G+ G + A+PSDIADA++ LV+ Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 43.7 bits (103), Expect = 9e-07 Identities = 34/143 (23%), Positives = 57/143 (39%), Gaps = 4/143 (2%) Query: 16 NSFIAALLGWTMDAFDYFIVVLVYADIAKTFHHSKAEVA---FVTTATLIMRPVGALLFG 72 I L +DA +++ V + + HS A + +M+ A + G Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 73 LWADRVGRRLPLMVDVMFYSVVGFLCAFAPNFTVLVILRLLYGIGMGGEWGLGAALAMEK 132 +DR GRR L+V + +V + A AP VL I R++ GI G + A + Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADI 123 Query: 133 VPVERRGFFSGLLQEGYAFGYLL 155 + R G + + FG + Sbjct: 124 TDGDERARHFGFMSACFGFGMVA 146
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 137 bits (347), Expect = 8e-42 Identities = 74/259 (28%), Positives = 123/259 (47%), Gaps = 18/259 (6%) Query: 2 AERLAGKVALVSGGARGMGASHVRSLVAEGAKVVFGDILDDEGKAVAAEVGEATRY---L 58 A+ + GK+A ++G A+G+G + R+L ++GA + D ++ + V + + R+ Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 59 HLDVTKPEDWDAAVATALAEFGRIDVLVNNAGIINIGTLEDYALSEWQRILDINLTGVFL 118 DV D A E G ID+LVN AG++ G + + EW+ +N TGVF Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 119 GIRAVVKPMKEAGRGSIINISSIEGMAGTIACHGYTATKFAVRGLTKSAALELGPSGIRV 178 R+V K M + GSI+ + S + Y ++K A TK LEL IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 179 NSIHPGLIKTPM--TEWVPEDIFQSA-------------LGRAAEPKEVSNLVVYLASDE 223 N + PG +T M + W E+ + L + A+P ++++ V++L S + Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 224 SSYSTGSEFVVDGGTTAGL 242 + + T VDGG T G+ Sbjct: 243 AGHITMHNLCVDGGATLGV 261
>PF06580#Sensor histidine kinase Length = 349 Score = 33.7 bits (77), Expect = 0.001 Identities = 13/77 (16%), Positives = 28/77 (36%), Gaps = 12/77 (15%) Query: 439 NAVRHAAATKLT------IAVEVADEVSIKVIDNGKGLPDDVSEA---GLKTLRRRAERV 489 N ++H A + V+++V + G + E+ GL+ +R R + + Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQML 325 Query: 490 GG---TLTVGAAAGGGT 503 G + + G Sbjct: 326 YGTEAQIKLSEKQGKVN 342
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 27.8 bits (62), Expect = 0.025 Identities = 8/31 (25%), Positives = 15/31 (48%) Query: 100 DKKLQKAAKNGDLPLSFDVTNIQPTASGAAT 130 KK++ A K G + S +V + + +A Sbjct: 11 PKKIRDARKKGQVAKSKEVVSTALIVALSAM 41
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 28.6 bits (63), Expect = 0.017 Identities = 9/14 (64%), Positives = 10/14 (71%) Query: 43 APLPQDPPPPPPPP 56 AP+ PPPPPPP Sbjct: 360 APVNNMMPPPPPPP 373
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 31.9 bits (72), Expect = 0.018 Identities = 24/111 (21%), Positives = 43/111 (38%), Gaps = 9/111 (8%) Query: 933 RIIMVDEIPLTPNGKLDETALAAVDNAEAVDGAAPPQTGTESALAELIAELLGQP--RVD 990 +M D + LD+ A D + T + + IAELL + + Sbjct: 199 FTVMTDSL-------LDQLQNAPADVQKTSANTGKKNVFTCENIRKQIAELLQETPEDIT 251 Query: 991 VTADFLALGLDSIMALSVVQAARARGIALRARLVLDCTSIRELAEAIDAES 1041 D L GLDS+ +++V+ R G + + + +I E + + S Sbjct: 252 DQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLTTRS 302
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 37.3 bits (86), Expect = 8e-05 Identities = 20/80 (25%), Positives = 33/80 (41%), Gaps = 2/80 (2%) Query: 290 PRPVVSTGGRTEPTRTDTERALANVFAELL--STPEVGRFDDFFALGGDSILSVQLASRA 347 P V T T T + AELL + ++ +D G DS+ + L + Sbjct: 214 PADVQKTSANTGKKNVFTCENIRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQW 273 Query: 348 RAAGLPVSPRMIFENPTVQQ 367 R G V+ + E PT+++ Sbjct: 274 RREGAEVTFVELAERPTIEE 293
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 30.1 bits (68), Expect = 0.045 Identities = 17/90 (18%), Positives = 36/90 (40%), Gaps = 5/90 (5%) Query: 657 VVITGGSGAIGLHYARYCLQRGTRNLTLLSRNGIEAAVLRELTGSHDAR--VSAPRCDIT 714 ++TG +G IG H ++ L+ G + + + + N L++ A+ + D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62 Query: 715 DRAAVTQAAARYAGSGATLLIHTAGIAQAR 744 DR +T +A + + R Sbjct: 63 DREGMTDL---FASGHFERVFISPHRLAVR 89
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 75.1 bits (184), Expect = 2e-16 Identities = 34/75 (45%), Positives = 47/75 (62%) Query: 5 PARSEDIREEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRRGIAVDFATLAET 64 E+IR+++AELL + + +L+ +GLDS+RIMTL +WRR G V F LAE Sbjct: 229 VFTCENIRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAER 288 Query: 65 PTIEAWAQLVTAGRQ 79 PTIE W +L+T Q Sbjct: 289 PTIEEWQKLLTTRSQ 303
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 30.6 bits (69), Expect = 0.006 Identities = 23/114 (20%), Positives = 37/114 (32%), Gaps = 11/114 (9%) Query: 22 VAEVLAEARKRAGA--------SGDADV---PINRMRAGDVSTYELAELLSPSLFADERI 70 ++ + + G S A+V +N M A A LLSPS +D I Sbjct: 103 TLAIIDKYQAEFGTQKVILIGYSFGAEVIPFVLNEMPARYRKNVLGAVLLSPSQSSDFEI 162 Query: 71 VVLEAAGEAGKDAAAVILSAAAEMPAGVVLVVVHSGGGRAKALATELQSLGAVV 124 V E + A + L + +L + L E++ V Sbjct: 163 HVSEMVTSDNQSARYLTLPEVNKQTTVPMLCLYGKEDDAPLHLCPEVKQPNVTV 216
>LIPOLPP20#LPP20 lipoprotein precursor signature. Length = 175 Score = 28.2 bits (62), Expect = 0.010 Identities = 22/80 (27%), Positives = 44/80 (55%), Gaps = 8/80 (10%) Query: 38 VVDDGELAFNTGRGTAKARA-IARDSRVVICVDDPHPPYSFVQVQGVAAVS----EDPAE 92 ++ + ++ ++T + TAKARA +A + + + D + V G ++S E ++ Sbjct: 72 LITNNDVDYSTNQATAKARANLAANLKSTLQKDLENEKTRTVDASGKRSISGTDTEKISQ 131 Query: 93 VLD---IATRTGARYMGADR 109 ++D IA++ ARY+G DR Sbjct: 132 LVDKELIASKMLARYVGKDR 151
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 47.4 bits (112), Expect = 5e-07 Identities = 34/161 (21%), Positives = 63/161 (39%), Gaps = 8/161 (4%) Query: 1185 LVTGGLGSIGLEIAGHLAAQGARHLVLTGRRAPGEAAQRRIDALSQQHGCEVRVIAADVA 1244 +TG IG +A LA+QGA + E ++ + +L + ADV Sbjct: 12 FITGAAQGIGEAVARTLASQGAH---IAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADVR 67 Query: 1245 DAHHVARLLGAVRAELPPVAGIVHAAGEIGTTPLSDLEDAEIDRVFAGKVWGAWHLSEAA 1304 D+ + + + E+ P+ +V+ AG + + L D E + F+ G ++ S + Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 1305 A----DLRLDFFVSTSSIASVWGGLGQTAYGAANAFLDGLA 1341 + D R V+ S + AY ++ A Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFT 168 Score = 41.2 bits (96), Expect = 4e-05 Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 4/113 (3%) Query: 3297 LITGGLGAIGLHLAAYLAQLGAGEIVLTSRRAPDAAARRAIDDITERYRCRVHTFAADVG 3356 ITG IG +A LA GA I + R+ F ADV Sbjct: 12 FITGAAQGIGEAVARTLASQGA-HIAAVDYNPEKLEKVVSSLKAEARHA---EAFPADVR 67 Query: 3357 DAAQVEQLLARIRAELPPLAGVAHLAGVLDDALLSQQSPERFRVALAPKAFGA 3409 D+A ++++ ARI E+ P+ + ++AGVL L+ S E + + + G Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 61.0 bits (148), Expect = 2e-11 Identities = 36/215 (16%), Positives = 80/215 (37%), Gaps = 30/215 (13%) Query: 185 AVLVLVVLLVVYRSAVTMLLPLVTILLSLVIAQAAVA--GYSQLTGSGVSNQSIVFLSAI 242 +LV +V+ + ++ L+P + + + L+ A +A GYS N +F + Sbjct: 348 IMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSI-------NTLTMFGMVL 400 Query: 243 MAGAGTDYAVFLISRYHDYLR-RGDDFDQAVRKALISIGKVITASASTVGITFLLIGFAR 301 G D A+ ++ + +A K++ I + A + F+ + F Sbjct: 401 AIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAF-- 458 Query: 302 MG-----VFKTVGISSAIGIGVAFLAAVTLLPAIMVL-------------AGPRGWIRPR 343 G +++ I+ + ++ L A+ L PA+ G GW Sbjct: 459 FGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTT 518 Query: 344 RELTTGLWRRSGIRIVRRPRTHLVASVLVLIILAS 378 + + + S +I+ +L+ L++ + Sbjct: 519 FDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVV 553
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 32.7 bits (74), Expect = 0.002 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 11/100 (11%) Query: 142 TRTTARLEDGEWVINGSKQFITNSGTDITSLVTVTAVTGTVG---ADKKEISTIIVPSGT 198 T + + L DG +VI+ +I + ++S + TGT KE+S I + + Sbjct: 31 TNSNSNLSDGLYVIDKGDGWILGEPSVVSSQILNPNETGTFSQSLTKSKEVS--INVNFS 88 Query: 199 PGFTVEPVYSKV----GWNASDTHPL--SFSDARVPEENL 232 GFT E + + V G + + + S S P E + Sbjct: 89 VGFTSEFIQASVEYGFGITIGEQNTIERSVSTTAGPNEYV 128
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 76.6 bits (188), Expect = 2e-19 Identities = 34/176 (19%), Positives = 64/176 (36%), Gaps = 9/176 (5%) Query: 16 PNRRSQLKSDRRLQLLSAAERLFAERGFLAVRLEDIGASAGVSGPAIYRHFPNKESLLVE 75 + Q + R +L A RLF+++G + L +I +AGV+ AIY HF +K L E Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 76 LLVGISTRLLAGARQV-RARSADAAAALDGLIDFHLDFALNEPDLIRIQDRDLAYLPKPA 134 + + + + D + L ++ L+ + E + + Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 135 ERQ-VRKAQRQYVEVWVGVLREL------NPELAEA-DARLTAHAVFGLLNSTPHS 182 E V++AQR + + L R A + G ++ + Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMEN 177
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 31.3 bits (71), Expect = 0.009 Identities = 69/364 (18%), Positives = 119/364 (32%), Gaps = 42/364 (11%) Query: 53 IGGSTTPASWLGRAAAIAGLTVALLAPAVGVWVESPHRRRVALSVLTALAVTLTGSMFFI 112 + S + G A+ L AP +G + RR V L L + ++ Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSL--AGAAVDYAIMAT 92 Query: 113 RDRPGYLWAGLVLLGATAACGDLASVPYNAMLRQLSTPRTAGRISGFGWAAGYVGSVLLL 172 L+ G ++ G T A G +A A + ++ R FG+ + G Sbjct: 93 APFLWVLYIGRIVAGITGATGAVAG----AYIADITDGDE--RARHFGFMSACFG----- 141 Query: 173 LVIYTGFIAGSGSGPDATRGLLRVPLRDGLYVREAMLVAAAWLALFALPLLFVAHRLTES 232 G +AG G GL+ G + A AAA L + Sbjct: 142 ----FGMVAGPVLG-----GLM------GGFSPHAPFFAAAALNGLNFLTGCFLLPESHK 186 Query: 233 AEGYRPTSMLGGYRKLWTEVREEWRRDRNLVYFLFASALFRDGLAAIFAFGAVLGVNVYG 292 E RP L+ F L AA++ + G + + Sbjct: 187 GER-RPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALW---VIFGEDRFH 242 Query: 293 ISQADVLVFGVAASVVAAVGA----VLGGFVDHRVGSKPVIVASLLA-IVVLGLTLMALS 347 + G++ + + + ++ G V R+G + ++ ++A L A Sbjct: 243 WDATTI---GISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATR 299 Query: 348 GPVAFWACGLLLCMFIGPSQSSSRALLLQMAKHGREGVAFGLYTMTGRAVSFVAPWLFSV 407 G +AF ++L G + +A+L + R+G G S V P LF+ Sbjct: 300 GWMAF--PIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357 Query: 408 FVDA 411 A Sbjct: 358 IYAA 361
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 82.8 bits (204), Expect = 7e-21 Identities = 54/200 (27%), Positives = 94/200 (47%), Gaps = 9/200 (4%) Query: 12 AVVTGASQNIGEALATELAARGHHLIVTARREDLLKDLAARLTEKYRVTVEVRPADLADA 71 A +TGA+Q IGEA+A LA++G H+ + L+ + + L + R E PAD+ D+ Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEAR-HAEAFPADVRDS 69 Query: 72 GERATLCDELAART--ISVLCANAGTATFGPVATLDPAGEKAQVQLNVLGVHDLTLAVLP 129 + + I +L AG G + +L +A +N GV + + +V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 130 GMVERRAGGILISGSAAGNSPIPYNATYAATKAFVNTFSESLRGELRGSGVHVTLLAPGP 189 M++RR+G I+ GS P A YA++KA F++ L EL + +++PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 190 VRTDL------PDDAEASIV 203 TD+ ++ ++ Sbjct: 190 TETDMQWSLWADENGAEQVI 209
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.2 bits (65), Expect = 0.035 Identities = 11/53 (20%), Positives = 15/53 (28%), Gaps = 3/53 (5%) Query: 437 QTVQQPAQPPPGPQ---APTGSRSPQAQSDYPPVPPNGPVPPMPEPAEPKGPG 486 Q VQ P +P P+ P +A P P P + Sbjct: 64 QAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKR 116
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 52.9 bits (127), Expect = 5e-09 Identities = 42/227 (18%), Positives = 87/227 (38%), Gaps = 15/227 (6%) Query: 187 IAIPLSFAVLVWVLGGVVAATLPVVLGALAIVGTMSVLRLISFATDVSTYALDLSIAMGL 246 AI L F V+ L + A +P + + ++GT ++L ++ + T + +A+GL Sbjct: 346 EAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFG-MVLAIGL 404 Query: 247 ALAIDYNLLIITRYREELARTEDRDR-ALYRTMATAGRTVLFSATT---VGLSMAVMAVF 302 +D ++++ + + + A ++M+ ++ A V + MA Sbjct: 405 L--VDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGS 462 Query: 303 PMYFLKSSAYTIVATAIIVAIAAVVITPA-AIVLLGPRLDTMDARRVMHRILHGQRSFRD 361 + + TIV+ + + A+++TPA LL P H G + + Sbjct: 463 TGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPV------SAEHHENKGGFFGWFN 516 Query: 362 PAHKPLVEQFWYRSTKYVLRRALPVGLSVVALLLLLGVPFLGVKWGF 408 V + S +L L ++ + V FL + F Sbjct: 517 TTFDHSVN-HYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSF 562
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 116 bits (292), Expect = 2e-33 Identities = 90/279 (32%), Positives = 131/279 (46%), Gaps = 25/279 (8%) Query: 6 AGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVR 65 A +EGK+AFITGAA+G G + A TLA +GA I A+D P+ L + V Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVD------------YNPEKLEKVVS 50 Query: 66 QVEALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMGPKTW 125 ++A R A DVRD A+ ++G +DI++ A + G ++ + + W Sbjct: 51 SLKAEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGL-IHSLSDEEW 109 Query: 126 RDMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLM 185 VN G + +R ++M +R GSIV S ++ Y +SK Sbjct: 110 EATFSVNSTGVFNASRSVSKYMMD-RRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFT 168 Query: 186 RTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFKVASRQMHVLPI 245 + + LEL NIR NIV P S T M + + ++E FK I Sbjct: 169 KCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFK--------TGI 220 Query: 246 PY---VEPADISNAILFLVSDDARYITGVALPVDGGALL 281 P +P+DI++A+LFLVS A +IT L VDGGA L Sbjct: 221 PLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGATL 259
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 109 bits (273), Expect = 6e-31 Identities = 75/250 (30%), Positives = 113/250 (45%), Gaps = 11/250 (4%) Query: 10 RVAVITGAGTGIGRASALVLAEHGADIVLAGRRPDPLQATAKEVEALGRRALIVPTDVTE 69 ++A ITGA GIG A A LA GA I P+ L+ ++A R A P DV + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 70 THQCQDLVDATLADFGRLDILVNNAGGGETKGITRWTEEEWHDVVDLNLGSVWFLSRCAV 129 + ++ + G +DILVN AG I ++EEW +N V+ SR Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 130 KPMMTQGSGAIVNISSGASLIAMPQAAIYAAAKAGVNNLTGSMAAAWGRKGIRVNCIACG 189 K MM + SG+IV + S + + A YA++KA T + IR N ++ G Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 190 AIRTD---GLLAD------AAKGGFDVDQLGAMNAMGRIAEPDEIGYGVLFFASDASSYC 240 + TD L AD KG + + G + ++A+P +I VLF S + + Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGI--PLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 241 SGQTLYIHGG 250 + L + GG Sbjct: 247 TMHNLCVDGG 256
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 156 bits (397), Expect = 1e-43 Identities = 92/401 (22%), Positives = 175/401 (43%), Gaps = 19/401 (4%) Query: 43 LWAMMIGFFMIMVDSTIVAIANPTIMADLHIGYDTVVWVTSAYLLGYAVVLLVAGRLGDR 102 +W ++ FF ++ + ++ ++ P I D + + WV +A++L +++ V G+L D+ Sbjct: 17 IWLCILSFFSVL-NEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 103 FGTKNLYLIGLAVFTVASVWCGLAGS-AAMLIAARVVQGVGAGVLTPQTLSTITRIFPPE 161 G K L L G+ + SV + S ++LI AR +QG GA + + R P E Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 162 RRGVAVSVWSATAGAASLVGPLAGGVLVDGLGWQWIFFVNVPIGVLGLALAYWLVPVLPT 221 RG A + + VGP GG++ + W ++ + + + L L + Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRI 195 Query: 222 QSHRFDLVGVGLSGVGMFLIVFGLQQGQAAHWQPWIWALIVAGVGFVTVFVFWQSVNVRE 281 + H FD+ G+ L VG+ + + + ++ V +FV V + Sbjct: 196 KGH-FDIKGIILMSVGIVFFMLFTTS--------YSISFLIVSVLSFLIFVKHIR-KVTD 245 Query: 282 PLIPLVIFADRDFSLCNI--GVAIISFAATAMMLPLTFYAQAVCGLSP-TRSALLIAPMA 338 P + + + F + + G+ + A M+P + V LS +++I P Sbjct: 246 PFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMM--KDVHQLSTAEIGSVIIFPGT 303 Query: 339 IANGVFAPFVGKIVDRYHPRPVLGFGFSLLAIALTWLTFEMSPATPIWRLVLPFFAMGVG 398 ++ +F G +VDR P VL G + L+++ +LT T W + + + G Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVS--FLTASFLLETTSWFMTIIIVFVLGG 361 Query: 399 MAFVWSPLTATATRNLSAQLAGAGSAVYNSVRQLGAVLGSA 439 ++F + ++ + +L Q AGAG ++ N L G A Sbjct: 362 LSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIA 402
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 39.6 bits (92), Expect = 5e-05 Identities = 19/105 (18%), Positives = 25/105 (23%), Gaps = 8/105 (7%) Query: 55 STDGPSAPAPAAPQTAQPALPAQTAPPAQTAQPARPAPQP-------AAAPGNGASTRPA 107 PAPA P + PA PP P P +P P Sbjct: 37 VHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEK 96 Query: 108 KPATPPPAEGDELQTLRGAAAAVVK-NMSASLEVPTATSVRAIPA 151 P P + + + AS TA + Sbjct: 97 PKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSST 141 Score = 38.4 bits (89), Expect = 9e-05 Identities = 22/129 (17%), Positives = 35/129 (27%), Gaps = 15/129 (11%) Query: 42 PEPTGDSVLAAPAST-DGPSAPAPAAPQTAQPALPAQTAPPAQTAQPARPAPQPAAAPGN 100 P P + P P P+ A + P +P + QP Sbjct: 61 EPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPK----- 115 Query: 101 GASTRPAKPATPPPAEGDELQTLRGAAAAVVKNMSASLEVPTATSVRAIPAKLLIDNRIV 160 R KP PA A A + +A+ + A + L N+ Sbjct: 116 ----RDVKPVESRPA-----SPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQ 166 Query: 161 INNQLKRTR 169 + + R Sbjct: 167 YPARAQALR 175
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 76.6 bits (188), Expect = 1e-18 Identities = 58/201 (28%), Positives = 91/201 (45%), Gaps = 2/201 (0%) Query: 2 QGFAGKVAVVTGAGSGIGQALAVELARSGAKVAISDVDLEGLAHTEEQLKAIGAQYKADR 61 +G GK+A +TGA GIG+A+A LA GA +A D + E L LKA +A Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 62 LDVTEREAFLAYADAVKEHFGKVNQIYNNAGIAFTGDVEVSQFKDIERVMDVDFWGVVNG 121 DV + A ++ G ++ + N AG+ G + ++ E V+ GV N Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 122 TKAFLPHLIASGDGHVVNVSSVFGLFSVPGQAAYNSAKFAVRGFTEALRQEMAAAGHPVA 181 +++ +++ G +V V S AAY S+K A FT+ L E+A + Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN--IR 181 Query: 182 VTTVHPGGIKTAIARNATAAE 202 V PG +T + + A E Sbjct: 182 CNIVSPGSTETDMQWSLWADE 202
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 75.9 bits (186), Expect = 3e-18 Identities = 53/195 (27%), Positives = 86/195 (44%), Gaps = 2/195 (1%) Query: 2 QGFAGKVAVVTGAGSGIGQALAVELGRAGAKLAISDVDTAGLAQTAEQLAAIGAPVKADR 61 +G GK+A +TGA GIG+A+A L GA +A D + L + L A +A Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 62 LDVTEREAFLAYADAVNEHYGRVNQIYNNAGITFIGSIEDSRFKDIERVVDVDFWGVVNG 121 DV + A + G ++ + N AG+ G I ++ E V+ GV N Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 122 TKAFLPHLIASGDGHVINISSALGLFSAPGQAAYVSAKFAVRGFTEALHQEMLRAGHPVR 181 +++ +++ G ++ + S AAY S+K A FT+ L E+ A + +R Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL--AEYNIR 181 Query: 182 VTTVHPGGIKTAFAR 196 V PG +T Sbjct: 182 CNIVSPGSTETDMQW 196
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 28.8 bits (64), Expect = 0.026 Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 11/62 (17%) Query: 202 KGKNAAEVVGDQNWIENDFIPTVAKRGAAIIDARGASSAASAASATTDAARDWLLGTPAG 261 K NAA + G NW D +P ++ I A G ++ S D +DW+ + G Sbjct: 65 KFNNAAIIKGAINW---DLMPQIS------IGAAGWTTLGSRGGNMVD--QDWMDSSNPG 113 Query: 262 DW 263 W Sbjct: 114 TW 115
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.4 bits (73), Expect = 0.004 Identities = 14/56 (25%), Positives = 21/56 (37%), Gaps = 9/56 (16%) Query: 33 LILVGPSGCGKTTTLNMIAGLEDISSGELRIGGERVNEKAPKDRDIAMVFQSYALY 88 ++L G G GK+T +N + GL+ S IG +D Y Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG---------TGKDSYEQIAGIVAY 645
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 54.0 bits (129), Expect = 5e-10 Identities = 42/166 (25%), Positives = 67/166 (40%), Gaps = 8/166 (4%) Query: 133 PGPLSTARWHDRLFAAPVTTNTQLLWYRPDLVLQPPRTWDAVVTEAARLHAAGRPSWIAV 192 P R++ +L A P+ L Y DL+ PP+TW+ + L A G+ A+ Sbjct: 117 PFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKS---AL 173 Query: 193 QANEGEGLVVWFNTLLASGGGRVLSEDGRRVTLTDTPAHRAATVNALRILKSVATAPGAD 252 N E W L+A+ GG + + + D A L L + + Sbjct: 174 MFNLQEPYFTW--PLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMN 231 Query: 253 PSITRTDEGTARLAVEQGRAALAVNWPYALASMLDNAVKGGVPFLP 298 TD A A +G A+ +N P+A +++ + V GV LP Sbjct: 232 AD---TDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLP 274
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 30.9 bits (70), Expect = 0.010 Identities = 30/171 (17%), Positives = 59/171 (34%), Gaps = 27/171 (15%) Query: 185 KPVDVADAIRGLPPKRRYEVLKALNDDRLADILQELPELDQAEVLSQLGTERSADVLEEM 244 P ++ + I+ P+ +L L+ + + IL LP Q V ++ ++ Sbjct: 124 DPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIAL------MDRT 177 Query: 245 DPDDAADLLGVLNPTDAEM-LLKRMDPGDSASVRRLLTHSPDTAGGLMTSNPVVLTPDTA 303 P+ ++ VL A + G +V ++ N + Sbjct: 178 SPEVVREVERVLEKKLASLSSEDYTSAGGVDNVVEII-------------NMADRKTEKF 224 Query: 304 VAEALARARDPDLTAALSSMVFVVRPPTATPTGRYLGCVPLQRLLREAPAE 354 + E+L DP+L + +FV +QR+LRE + Sbjct: 225 IIESL-EEEDPELAEEIKKKMFVFEDIVLLDDR------SIQRVLREIDGQ 268
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 37.7 bits (87), Expect = 6e-05 Identities = 21/87 (24%), Positives = 24/87 (27%), Gaps = 3/87 (3%) Query: 369 PPAGPPPFGAPPPFAPPPSGPPPFAPPPSGPPPFGPPPPDAGPVPAPPAGVAPQAAPSPP 428 PP P P P PP P P P P PV P Sbjct: 60 AVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVES 119 Query: 429 AGPAP---QAPSPAAAGPAPNAPKKPG 452 +P AP+ + A A KP Sbjct: 120 RPASPFENTAPARLTSSTATAATSKPV 146 Score = 30.3 bits (68), Expect = 0.013 Identities = 19/85 (22%), Positives = 22/85 (25%) Query: 370 PAGPPPFGAPPPFAPPPSGPPPFAPPPSGPPPFGPPPPDAGPVPAPPAGVAPQAAPSPPA 429 PA P P P P P P P P P AP P+ P P Sbjct: 41 PAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP 100 Query: 430 GPAPQAPSPAAAGPAPNAPKKPGPV 454 P + P + P Sbjct: 101 KPVKKVQEQPKRDVKPVESRPASPF 125 Score = 29.2 bits (65), Expect = 0.027 Identities = 18/109 (16%), Positives = 24/109 (22%) Query: 346 PTPQQAPTQVPGCTVICISSQGSPPAGPPPFGAPPPFAPPPSGPPPFAPPPSGPPPFGPP 405 Q P V+ + P PP P P P P Sbjct: 54 DLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRD 113 Query: 406 PPDAGPVPAPPAGVAPQAAPSPPAGPAPQAPSPAAAGPAPNAPKKPGPV 454 PA P A + A + + P A + P Sbjct: 114 VKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQ 162
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 78.1 bits (192), Expect = 2e-21 Identities = 24/75 (32%), Positives = 42/75 (56%), Gaps = 2/75 (2%) Query: 5 LSWEHMLVLVVVGLVVLGPERLPGAIRWTSNALRQARDYLSGVTTQLREDLG-PEFDDLR 63 + + +L++ ++GLVVLGP+RLP A++ + +R R + V +L ++L EF D Sbjct: 4 IGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSL 63 Query: 64 VPLSELQKLRGMTPR 78 + E L +TP Sbjct: 64 KKV-EKASLTNLTPE 77
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 74.7 bits (183), Expect = 1e-16 Identities = 42/201 (20%), Positives = 73/201 (36%), Gaps = 29/201 (14%) Query: 197 NGEAPAGRFAKVAAATAG---AVVTIESKSDQEGMQGSGVVIDGRGYIVTNNHVISEAAN 253 N P ++ T G V I+ ++ SGVV+ G+ ++TN HV+ Sbjct: 68 NVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVV-GKDTLLTNKHVVDATHG 126 Query: 254 NPSQFKTTVVFNDGKEVP------ANLVGRDPKTDLAVLKVDNV-------DNLSVARLG 300 +P K + P + + DLA++K + + A + Sbjct: 127 DPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMS 186 Query: 301 DSDKVRVGDEVLAAGAPLGLRSTVTHGIVSALHRPVPLSGEGSDTDTVIDAVQTDASINH 360 ++ + +V + G P +G T +A+Q D S Sbjct: 187 NNAETQVNQNITVTGYPGDKPVATMW------------ESKGKITYLKGEAMQYDLSTTG 234 Query: 361 GNSGGPLIDMNSQVIGIDTAG 381 GNSG P+ + ++VIGI G Sbjct: 235 GNSGSPVFNEKNEVIGIHWGG 255
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.8 bits (160), Expect = 5e-15 Identities = 37/193 (19%), Positives = 59/193 (30%), Gaps = 18/193 (9%) Query: 1 MRSADLTAAARIRDAAIEQFGEHGF-GVGLRRIAEAAGVSAALVIHHFGSKEGLRKACDD 59 + I D A+ F + G L IA+AAGV+ + HF K L + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 60 HIAEQIRESKTEALQTNDPAVW----------FGQLAEIEEFAPLIAYVLRSMQTGGDLA 109 I E + E E L+ + + G++A Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 110 KM------LWRQMIENAEGYLEEGVRAGTIKPSRDPRARAKYLGITGGGGLLLYLQMHDN 163 + L + + E L+ + A + R RA + GL+ Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTR-RAAIIMRGYISGLMENWLFAPQ 183 Query: 164 PTDLRAVLRDYSR 176 DL+ RDY Sbjct: 184 SFDLKKEARDYVA 196
>PF05844#YopD protein Length = 295 Score = 27.7 bits (61), Expect = 0.043 Identities = 14/32 (43%), Positives = 15/32 (46%), Gaps = 8/32 (25%) Query: 115 PGGAGRAVDDHAQRARGRPAAAGEGGQATATR 146 PG AGR+V G P AA E Q A R Sbjct: 22 PGAAGRSV--------GTPQAAAELPQVPAAR 45
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 31.9 bits (72), Expect = 0.001 Identities = 15/54 (27%), Positives = 30/54 (55%) Query: 37 DSGATDPAIRFVVLALLAVDGVLSALAGALLLPLYIGTVPFPISGLISGLLNAA 90 ++GA D ++ + L +V +SA A L+ + + ++G+ISG+L A+ Sbjct: 360 ETGAIDASLTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEAS 413
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 48.9 bits (116), Expect = 3e-09 Identities = 26/193 (13%), Positives = 60/193 (31%), Gaps = 10/193 (5%) Query: 38 SRSRRRGEVLERALYEATLAELTEVGYGGLTMEGIAARAHTGKAALYRRWDTKCELVHAA 97 ++++ + + + + L ++ G ++ IA A + A+Y + K +L Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 98 LVFALPPVPELRSGRSA----------RENLLAMFTAQRDLLAGKTAFPGIEVIQQLLHE 147 + + EL A RE L+ + + + I + + E Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 148 PEMRAIFADAVVRPRLKIVESILQSAVQDGDLDPKSITPLTARIGSALINQHFLLNGSPP 207 + + +E L+ ++ L +T A I I+ P Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 208 NRRELALIVDTVI 220 +L + Sbjct: 183 QSFDLKKEARDYV 195
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 172 bits (437), Expect = 6e-48 Identities = 102/442 (23%), Positives = 171/442 (38%), Gaps = 61/442 (13%) Query: 53 RNVAIVAHVDHGKTTLVDAMLRQSGALHHRGD-DTQERILDSGDLEKEKGITILAKNTAV 111 N+ ++AHVD GKTTL +++L SGA+ G D D+ LE+++GITI T+ Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSF 63 Query: 112 HRHHPDGSVTVINVIDTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKALA 171 + T +N+IDTPGH DF EV R LS++DG +LL+ A +G QTR + Sbjct: 64 QWEN-----TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRK 118 Query: 172 AHLPVILVVNKTDRPDARIAEVVEASHDLLLDVA----------------SDLDDEAAKA 215 +P I +NK D+ ++ V + + L ++ Sbjct: 119 MGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTV 178 Query: 216 AEHALGLPTLYASG------------RAGVAS-TEQPA-DGEVPAGENLDPLFDVLLEHI 261 E L Y SG + + P G +D L +V+ Sbjct: 179 IEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKF 238 Query: 262 PAPSGDPEAPLQALVTNLDASTFLGRLALIRIYNGKLRKGQQVAWMREVDGLPVITSAKI 321 + + ++ L V ++ S RLA IR+Y+G L V + KI Sbjct: 239 YSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVR-------ISEKEKIKI 291 Query: 322 TELLATEGVERSPTDEAIAGDIVAVAGLP---EIMIGDTLADPDHAHALPRITVDEPAIS 378 TE+ + E D+A +G+IV + ++GDT P I P + Sbjct: 292 TEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRER----IENPLPLLQ 347 Query: 379 VTIGTNTSPLAGKVPGHKLTARLVRNRLDQELVGNVSIRVVDIGRPDAWEVQGRGELALA 438 T+ + L L + + +R + G++ + Sbjct: 348 TTVEPSKPQQRE-----MLLDAL--LEISDS---DPLLRYYVDSATHEIILSFLGKVQME 397 Query: 439 VLVEQMRRE-GFELTVGKPQVV 459 V ++ + E+ + +P V+ Sbjct: 398 VTCALLQEKYHVEIEIKEPTVI 419 Score = 42.9 bits (101), Expect = 4e-06 Identities = 18/84 (21%), Positives = 33/84 (39%), Gaps = 1/84 (1%) Query: 466 QLHEPFEAMTIDCPEEFVGAITQLMAARKGRMEEMTNHAAGWVRMDFIVPSRGLIGFRTD 525 +L EP+ + I P+E++ + + T V + +P+R + +R+D Sbjct: 534 ELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVD-TQLKNNEVILSGEIPARCIQEYRSD 592 Query: 526 FLTITRGTGIANAVFDGYRPWAGE 549 T G + GY GE Sbjct: 593 LTFFTNGRSVCLTELKGYHVTTGE 616
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 30.3 bits (68), Expect = 0.008 Identities = 11/43 (25%), Positives = 22/43 (51%) Query: 208 RLATASADDVAAVVDDVLIAACADALGAARAVMDLAVEYAKTR 250 R+ S + A+++D+ +A G A++ A+E+AK Sbjct: 79 RIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKEN 121
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.2 bits (161), Expect = 1e-14 Identities = 41/203 (20%), Positives = 70/203 (34%), Gaps = 20/203 (9%) Query: 18 RRAEILATAASLIASSGLR-TSLQEIADAAGILPGSLYHHFESKEAILVELTRRYQEDLE 76 R IL A L + G+ TSL EIA AAG+ G++Y HF+ K + E+ ++ Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI---WELSES 68 Query: 77 RIGRAAQARLDEPDSRPVPEQIIELGSAIANCAVE-HRAALQMSFY---EGPGTDPELTK 132 IG + P+ L + + E R L + E G + + Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 133 LTRQRPVAIQEAMLQTLRAGRWSGYIKPDIDLPTLADRICQTMLQVGLDVMRHTASADP- 191 R + + + QTL+ + + D+ A + + + P Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG-----LMENWLFAPQ 183 Query: 192 ------VAELLCRIILQGLASRP 208 A I+L+ P Sbjct: 184 SFDLKKEARDYVAILLEMYLLCP 206 Score = 46.2 bits (109), Expect = 6e-08 Identities = 19/145 (13%), Positives = 40/145 (27%), Gaps = 9/145 (6%) Query: 240 DKAALVRAVARAEFGRRGYEVTTIRDIAAAAGLGTGTVYRVIGSKDELLDSIM-RSFGKK 298 + ++ A F ++G T++ +IA AAG+ G +Y K +L I S Sbjct: 12 TRQHILDV-ALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 299 VEAGWVSVLRSDATPTEKLDALSWVNVNALDQFSDEFRIQLAWMRLS------PPTANPG 352 E + P L + + + + Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 353 WSYATRLRQ-MKSLLSEGLRTGEIA 376 + ++ L + + Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLP 155
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 59.3 bits (143), Expect = 2e-12 Identities = 62/286 (21%), Positives = 102/286 (35%), Gaps = 71/286 (24%) Query: 10 DGKRALVVGGATGMGAAAAKSAAELGAEVIVLDYAPVTYDV-----------AKSIQVDL 58 +GK A + G A G+G A A++ A GA + +DY P + A++ D+ Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 59 RDPASIDAALEQLD---GPVHAVFSAAGIAE-GTTDLM---------AINFLGHRYLIER 105 RD A+ID +++ GP+ + + AG+ G + ++N G Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 106 LLERNQLPSGSAICFISSVAGMGWENDLDLLNEFLATPDFATAQEWVKAHEPE-GIIHYG 164 + + +I + S A P + Y Sbjct: 127 VSKYMMDRRSGSIVTVGSNP----------------------------AGVPRTSMAAYA 158 Query: 165 FSKKVVNAYVATQGYPLLKKGIRINAICPGPTDTPLAQANADLWLT----------FAQD 214 SK + G L + IR N + PG T+T + + LW + Sbjct: 159 SSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWS---LWADENGAEQVIKGSLET 215 Query: 215 YRDETG---SKVHTPEQMGDVMAFLNSAAAFGINGITLLVDYGHTM 257 ++ TG K+ P + D + FL S A I L VD G T+ Sbjct: 216 FK--TGIPLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGATL 259
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 32.4 bits (74), Expect = 9e-04 Identities = 24/164 (14%), Positives = 50/164 (30%), Gaps = 31/164 (18%) Query: 3 RVVIVGGHGKVALQLSAILTQRGDAVTSL---------FRNPDHADDVAATGAKPVVADI 53 + ++ G G + +S L + G V + + +A G + D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 54 ERLDTDALA------GHDAVVFSAGAGG-----GNPARTYAVDRDAAIRVVDAAARSGVK 102 D + + + V S NP + + +++ + ++ Sbjct: 62 A--DREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 103 RFVMVS---YFGAGP----DHGVPQDDPFFPYAESKAAAD--AH 137 + S +G D P YA +K A + AH Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAH 163
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.8 bits (67), Expect = 0.036 Identities = 38/234 (16%), Positives = 81/234 (34%), Gaps = 32/234 (13%) Query: 159 LAALFADGTGPVPELGTTIGLLPAWKIVLILLVLAVLG--LRDKVIFLAAR--------G 208 + ++ A G G P +G I W +L++ ++ ++ K++ R G Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKG 203 Query: 209 EVYASMAVTFLFGAPDMIVGSKVVFLVIWMGAATSKLNKHFPFVISTMMSNNPLVRPRWL 268 + S+ + F + FL++ + + FV +P V P Sbjct: 204 IILMSVGIVFFMLFTTS---YSISFLIVSVLS-------FLIFVKHIRKVTDPFVDPGLG 253 Query: 269 KRRFFEKFPDDLRPGRLSRWIAHLSTA-IEMLVPLPLFFCHGGWPVTVAAVVMVCFHLGI 327 K F G L I + A +VP + H + +V++ + + Sbjct: 254 KNIPFMI-------GVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSV 306 Query: 328 LVSIPMG---VPLEWNVFMIF-GVLSLFVAHTGIGLGDLRHPVVVAVLFVVIAG 377 ++ +G V ++++ GV L V+ + ++ V + G Sbjct: 307 IIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG 360
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 71.7 bits (176), Expect = 3e-15 Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 401 EALHAAERGEPVILVRDHTRPEDVSGMLA--ARGIVTEVGGAASHAAVVSRELGRVAVVG 458 E A E +++ + P D + + +G T++GG SH+A++SR L AVVG Sbjct: 146 ETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSRSLEIPAVVG 205 Query: 459 CGAGVAAMLAGRRITVDGAEGEV 481 + G + VDG EG V Sbjct: 206 TKEVTEKIQHGDMVIVDGIEGIV 228
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 66.2 bits (161), Expect = 1e-14 Identities = 53/206 (25%), Positives = 90/206 (43%), Gaps = 12/206 (5%) Query: 17 LQGKVAVITGGAGGIGRALGRRLGHEGMKVVLADVLADPLQEATRALADEGIEAAGVVTD 76 ++GK+A ITG A GIG A+ R L +G + D + L++ +L E A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 77 VTDYSSVEALAKEALRRFGAVDVVCNNAGTGAVSEGYLWEHDLADWRWGIDVNVLGVIHG 136 V D ++++ + R G +D++ N AG + G + +W VN GV + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGV--LRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 137 LKAFVPILLERGEGHVVNTCSGNGGFAPIARGAMGGPATAVYPMTKAAVLCLTESLYTHL 196 ++ +++R G +V S G + A Y +KAA + T+ L L Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAA--------YASSKAAAVMFTKCL--GL 173 Query: 197 EMTGTRVRAHVLFPGGFLNTGIWESW 222 E+ +R +++ PG W W Sbjct: 174 ELAEYNIRCNIVSPGSTETDMQWSLW 199
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 48.1 bits (114), Expect = 4e-09 Identities = 23/119 (19%), Positives = 45/119 (37%), Gaps = 13/119 (10%) Query: 19 ILGIVVDMLDTGGYEAVQLREVARRARVSMATIYKRYRTRDELIVAALEGWMDANRYARL 78 IL + + + G + L E+A+ A V+ IY ++ + +L E + + Sbjct: 16 ILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL-----SESNI 70 Query: 79 PSLIDELPGESMYSDLMHVMRTIFE-------PWERHPLMLRSYFQARSGPGGKRLIRR 130 L E + D + V+R I ER L++ F G ++++ Sbjct: 71 GELELEYQAK-FPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 87.8 bits (217), Expect = 1e-22 Identities = 75/275 (27%), Positives = 123/275 (44%), Gaps = 31/275 (11%) Query: 4 LDGKVAFITGVARGQGRSHAVRLAREGANIIGIDICADIAANGYPMACRAELDQTVALVE 63 ++GK+AFITG A+G G + A LA +GA+I +D E + V Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVD-------------YNPEKLEKVVSSL 52 Query: 64 EAGGKMLGTV-ADVRDFGQVKAALDAGVEQFGRLDIVLANAGIA-PLAFRQLSIEEELAQ 121 +A + ADVRD + + G +DI++ AG+ P LS E + Sbjct: 53 KAEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDE----E 108 Query: 122 WRAVTGVNLDGAYHTAWAAIPHLLAGNRGGVIIFTSSTAGIKGFGGLQGGGLGYAASKHG 181 W A VN G ++ + + +++ G ++ S+ AG+ + YA+SK Sbjct: 109 WEATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVP-----RTSMAAYASSKAA 163 Query: 182 IVGLMRTLADALAPLNIRVNTVHPTAVNTMMA----TNDDMIEFLQKNPGAGPHLQNPMP 237 V + L LA NIR N V P + T M +++ E Q G+ + +P Sbjct: 164 AVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAE--QVIKGSLETFKTGIP 221 Query: 238 VGML-EPEDVSAAIAYLVSDEARYVTGVTFPVDAG 271 + L +P D++ A+ +LVS +A ++T VD G Sbjct: 222 LKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 103 bits (259), Expect = 1e-28 Identities = 82/272 (30%), Positives = 123/272 (45%), Gaps = 27/272 (9%) Query: 10 VAGKRVLITGAARGMGRSHAVRLAEQGADCILVDICCTPTGLDYPLATEEDLNETVRLVE 69 + GK ITGAA+G+G + A LA QGA +DY E + +++ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHI---------AAVDYNPEKLEKVVSSLKAEA 56 Query: 70 KHGSRAVPKIVDVRDEAAMKAAVDAAVDELGGLDGAVANAGVLTVGTWDTTTAEQWRLVL 129 +H + A P DVRD AA+ E+G +D V AGVL G + + E+W Sbjct: 57 RH-AEAFP--ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATF 113 Query: 130 DVNLIGAWNTCAAALPHLIGGGGGSLVNISSSAGIKGTPL--HLPYTASKHGIVGMTLAL 187 VN G +N + +++ GS+V + S+ G P Y +SK V T L Sbjct: 114 SVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCL 171 Query: 188 ANELAAQNIRVNTVHPTGVATGMAPPGMHALIAEQ-------RPDLVPIFLNALPAPLIE 240 ELA NIR N V P T M +L A++ + L L + Sbjct: 172 GLELAEYNIRCNIVSPGSTETDM----QWSLWADENGAEQVIKGSLETFKTGIPLKKLAK 227 Query: 241 ASDVSNAVLYLISDESRYVTGLELKVDAGVTI 272 SD+++AVL+L+S ++ ++T L VD G T+ Sbjct: 228 PSDIADAVLFLVSGQAGHITMHNLCVDGGATL 259
>PERTACTIN#Pertactin signature. Length = 922 Score = 33.2 bits (75), Expect = 0.002 Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 1/77 (1%) Query: 22 GSEALVQAKVYHLPVAAPVRVLTQPPPPQSAALMLEAATPPQPPQALPNAGFAQLPA-RI 80 G +LV AK P AP P P + PPQPPQ P A Q PA R Sbjct: 558 GQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRE 617 Query: 81 QQAADQAAASGAALSVA 97 AA AA + + +A Sbjct: 618 LSAAANAAVNTGGVGLA 634
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 27.3 bits (60), Expect = 0.041 Identities = 12/79 (15%), Positives = 23/79 (29%), Gaps = 3/79 (3%) Query: 94 KVAPPKPSKLELFNAALAEAEGGPTT---EAAKPKKKAATSGAKKAAKAAEPEAAASEAA 150 +V+P + + A E PT E A + ++ E +E+ Sbjct: 1128 QVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTEST 1187 Query: 151 EPEAAAAPAEGGEQAESSA 169 + E E + Sbjct: 1188 TVNTGNSVVENPENTTPAT 1206
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 42.5 bits (100), Expect = 8e-07 Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 7/99 (7%) Query: 47 DLDSGQVLAGRDPNVAHPPASTIKTLLAQVVLDEV-----SLDATVVADAADTQVECNCV 101 DL SG+ L + P ST K +L VL V L+ + D V+ + V Sbjct: 46 DLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDL-VDYSPV 104 Query: 102 GIK-PGRSYTARQLLDALLLVSGNDAANTLAHMLGGPEA 139 K T +L A + +S N AAN L +GGP Sbjct: 105 SEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAG 143
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.7 bits (126), Expect = 7e-11 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%) Query: 1 MARTQQQRREETVARLLDASIATIIEVGYARASAAVITKRAGVSVGALFRHFDTMGDFMA 60 MAR +Q +ET +LD ++ + G + S I K AGV+ GA++ HF D + Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 ATASEVLRRQLESFTKRVADIPAD--QPVLEVVLGILRDLTSGP 102 E + A P D + E+++ +L + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEE 104
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 34.7 bits (80), Expect = 0.001 Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 24/106 (22%) Query: 18 DAMPYDVIIRDGLWFDGTGGAALTRTLGIRDGVLVDVAESLDEAGCP------------- 64 + D +I + L D G + +G++DG + ++ +AG P Sbjct: 64 EGGAVDTVITNALILDHWG--IVKADIGLKDGRIA----AIGKAGNPDMQPGVTIIVGPG 117 Query: 65 -EVIDAAGKWVLPGFIDVHTHYDAEVLLDPGLRESVRHGVTTVLLG 109 EVI GK V G +D H H+ ++ E++ G+T +L G Sbjct: 118 TEVIAGEGKIVTAGGMDSHIHFICPQQIE----EALMSGLTCMLGG 159
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 56.4 bits (136), Expect = 5e-10 Identities = 53/276 (19%), Positives = 101/276 (36%), Gaps = 39/276 (14%) Query: 144 QGDALANESVDAIRNIVEHTPP--PPGVKAYVT-GAAPLVTDQFEVGSKGIFKVTVITVL 200 A A ++ AI+ + P P G+K P V K +F+ ++ L Sbjct: 294 ATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFL 353 Query: 201 VILAMLLWVYRSVTAVFVLVTVIVEMAAARGIVAFLGSVGLIGLSTYATNLLTL--LVIA 258 V+ L +++ A + + V LG+ ++ Y+ N LT+ +V+A Sbjct: 354 VMYLFL----QNMRATLIPTIAVP--------VVLLGTFAILAAFGYSINTLTMFGMVLA 401 Query: 259 AGT--DYAIFFVGRYHEARHEGQD--RETAYYTMYRGTTHVVLGSGLTVAGAVLCLRF-- 312 G D AI V E + +E +M ++G + ++ + + F Sbjct: 402 IGLLVDDAIVVVENVERVMMEDKLPPKEATEKSM-SQIQGALVGIAMVLSAVFIPMAFFG 460 Query: 313 -TRLNYFQSLGIPAAIGIGVALAAALSLTPAVITV-------------GSLFGLFDPKRQ 358 + ++ I + +++ AL LTPA+ G FG F+ Sbjct: 461 GSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFD 520 Query: 359 MATRGWRRIGTAIVRWPGPILVVATG-VALVGLLAL 393 + + I+ G L++ VA + +L L Sbjct: 521 HSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFL 556 Score = 41.7 bits (98), Expect = 2e-05 Identities = 27/167 (16%), Positives = 62/167 (37%), Gaps = 17/167 (10%) Query: 760 DLLIAGIAALSLILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLVWQDILGIKLYWI 819 +++ A+ L+ L+M L +++ A ++ V + L +F + G + + Sbjct: 339 EVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAA-----FGYSINTL 393 Query: 820 CLALSVIILLAVGSDYNLLL--ISRFREEIHAGLNTGIIRSMAGSGAVVTSAGLVFAFTM 877 + V+ + + D +++ + R E +SM+ + +V Sbjct: 394 TMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMV---LS 450 Query: 878 ASFVSASLL------VLGQIGTTIALGLLFDTLIVRSFMTPSVAALL 918 A F+ + + Q TI + L+ TP++ A L Sbjct: 451 AVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALIL-TPALCATL 496
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 27.0 bits (60), Expect = 0.009 Identities = 10/59 (16%), Positives = 22/59 (37%), Gaps = 7/59 (11%) Query: 5 SIASLVKRG-WMVLVVVVVVGVAGFCVYRLHGIFGSHNNTSAAGGISDQTEPFSPKHIT 62 + + ++VL++ + + L G+F + +QT PF K + Sbjct: 3 DLVFAGNKALYLVLILSGWPTIVATIIGLLVGLF------QTVTQLQEQTLPFGIKLLG 55
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.7 bits (165), Expect = 3e-16 Identities = 29/163 (17%), Positives = 56/163 (34%), Gaps = 11/163 (6%) Query: 18 WSPREAEILAVTLRLLQEHGYDQLTVDAVAGAAHASKATVYRRWPSKAELVLAAFIEGVR 77 IL V LRL + G ++ +A AA ++ +Y + K++L + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 78 QV--AVPPNTGTLRGDLLALGETVCEQVGHHASTI--RAVMFEVSRHPAL-------NDA 126 + GD L++ + V T R ++ E+ H Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 127 LQHQFLDQRRALIEHVLHQAVDRGEISADAISDELWDLLPGYL 169 Q + IE L ++ + AD ++ ++ GY+ Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>CHLAMIDIAOM6#Chlamydia cysteine-rich outer membrane protein 6 signature. Length = 547 Score = 31.6 bits (71), Expect = 0.005 Identities = 15/39 (38%), Positives = 19/39 (48%) Query: 91 PPGSTVVVPADGYYQVRRHAAEDLAPAGVTVIEASSAQI 129 P + V G +R ED GVTV+EA+ AQI Sbjct: 332 PVEYVISVSNPGDLVLRDVVVEDTLSPGVTVLEAAGAQI 370
>PF06872#EspG protein Length = 398 Score = 30.8 bits (69), Expect = 0.008 Identities = 14/50 (28%), Positives = 26/50 (52%) Query: 163 PDAETTLLMIEATDEFRVPPPGPLGRHFPFDPSQATIPEPQALDDDPAHD 212 P+ E L+++EA ++ R+ P+ RH P+ T+P+ + D H Sbjct: 122 PNNEKFLVLLEANEQNRLLQSLPINRHMPYIQVHHTLPQEELTDLLSMHK 171
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 32.5 bits (74), Expect = 0.002 Identities = 19/84 (22%), Positives = 34/84 (40%), Gaps = 3/84 (3%) Query: 40 PKNKPSDTVLVFMHPIGGGAYLP--MINALARAGHHVIYCNSRFRGTDSALLMEKVVEDL 97 + +++F+ GG A L + L + G V+ +S + + V +D Sbjct: 45 ASSHTKPPLVIFLSGDGGWATLDKAVGGILQQQGWPVVGWSS-LKYYWKQKDPKDVTQDT 103 Query: 98 GECIKDAKKRLGYTKVVLAGWSGG 121 I + G KV+L G+S G Sbjct: 104 LAIIDKYQAEFGTQKVILIGYSFG 127
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 75.4 bits (185), Expect = 5e-19 Identities = 33/164 (20%), Positives = 56/164 (34%), Gaps = 9/164 (5%) Query: 14 AKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFADKEDLLAALAE-S 72 + ++TRQ I A +LF+++G T+L +I AAG + Y +F DK DL + + E S Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 73 FLHEVVTPSGLSVHLPDSPDD------DAFFTAVVTGYWNMFKQNIGIMIAVAQLAATQQ 126 + P P + VT + + I+ + Sbjct: 67 ESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT--EERRRLLMEIIFHKCEFVGEMA 124 Query: 127 RFAAVQNEFRRFGIDLVAASVRRAQEQGYGAELHPQHTAAAIAL 170 Q D + +++ E AA I Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMR 168
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.6 bits (64), Expect = 0.028 Identities = 15/111 (13%), Positives = 36/111 (32%), Gaps = 16/111 (14%) Query: 6 QAQAAAAAAGAPVPHILVADNSPAALGNPFLICDEIKGETIARRIQRRLDAADGHAARAH 65 +++ + V I+V + G+ L + E + Q L A R Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 66 LLGQCAHAVAAIHRAEIDRIQDPGLRR-------------QDQLTEWRQRL 103 +L + ++ E+ +P + ++Q + W+ + Sbjct: 155 IL---SRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQK 202
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.3 bits (138), Expect = 3e-12 Identities = 26/140 (18%), Positives = 47/140 (33%), Gaps = 2/140 (1%) Query: 12 RARIRHAALREFGEKGYEGATIRSIAAAAGVSSGLLRHHFGSKQELRQACDDYLVKTMRD 71 R I ALR F ++G ++ IA AAGV+ G + HF K +L + + + Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 72 LNAQVQDNAKRGDVHYVSARIPLGQHQDYITRALVEGGAGELFDALVSMTEEWLASADEH 131 L + Q + + + + + +T +F E Sbjct: 73 LELEYQAKFPGDPLSVLREIL-IHVLESTVTEERRRLLMEIIF-HKCEFVGEMAVVQQAQ 130 Query: 132 RAEPADVDAKSRATLITAMA 151 R + + TL + Sbjct: 131 RNLCLESYDRIEQTLKHCIE 150
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.6 bits (82), Expect = 2e-04 Identities = 29/138 (21%), Positives = 51/138 (36%), Gaps = 16/138 (11%) Query: 27 RNALRLILTAVLARGHILIEDLPGLGKTLIARS---FAAALGLQFTRVQ---FTPDLLPA 80 + R++ + ++I G GK L+AR+ + F + DL+ + Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIES 206 Query: 81 DLLG------STIYDMQSGRFAFRAGPIFTNLLLADEINRTPPKTQAALLEAMAEGQVSI 134 +L G + +GRF G L DEI P Q LL + +G+ + Sbjct: 207 ELFGHEKGAFTGAQTRSTGRFEQAEG----GTLFLDEIGDMPMDAQTRLLRVLQQGEYTT 262 Query: 135 DGETHRLPKPFIVLATDN 152 G + ++A N Sbjct: 263 VGGRTPIRSDVRIVAATN 280
>PERTACTIN#Pertactin signature. Length = 922 Score = 28.9 bits (64), Expect = 0.030 Identities = 18/54 (33%), Positives = 20/54 (37%) Query: 113 LARLFASHGLSPAPPPGTGASPPPHPAAPPAPPPQHPQRPRDGSQDTLGILLAG 166 L A PAP PG P P P PPQ PQ P+ + AG Sbjct: 562 LVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAG 615
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 45.8 bits (108), Expect = 5e-08 Identities = 21/94 (22%), Positives = 38/94 (40%), Gaps = 9/94 (9%) Query: 114 STPLHAYRRHFDIAVFAAYELMQRVCPDMIGAGGGAIINITSVASRLPGDGPYADRSGGV 173 S + F + + + V M+ G+I+ + S + +P Sbjct: 103 SLSDEEWEATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTS--------- 153 Query: 174 LPGYGGSKAALEHLTQCVAYDLADHRIAVNALSP 207 + Y SKAA T+C+ +LA++ I N +SP Sbjct: 154 MAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 73.5 bits (180), Expect = 3e-18 Identities = 30/183 (16%), Positives = 59/183 (32%), Gaps = 14/183 (7%) Query: 26 PGAGRPRDPRIDSAILSATAELLVQTGYSNISLAAVAERAGTTKSALYRRWSSKAELVHE 85 + IL L Q G S+ SL +A+ AG T+ A+Y + K++L E Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 86 AAFPTAPTALEAPAGDIAADMRMMIEATRDV----FTTPVVRAALPGLV------ADMTA 135 + E A + R++ + V L+ + Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 136 DPALNARVMSRFA-DLFTAVRVRLREAVDRGEAHRDVDPDRLIELIGGA---TMLRMLLR 191 + A+ + + + + L+ ++ D+ R ++ G M L Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181 Query: 192 PEE 194 P+ Sbjct: 182 PQS 184
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 41.7 bits (98), Expect = 1e-05 Identities = 43/189 (22%), Positives = 69/189 (36%), Gaps = 38/189 (20%) Query: 744 ILLTGATGFLGPFLLSSLLARTPYTVHALVRATDPGHGLDRIVA----SLRKAQLWTPAL 799 L+TGA GF+G + LL V G+D + SL++A+ L Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVV-----------GIDNLNDYYDVSLKQAR-----L 46 Query: 800 EAEVRARVRVICGDLAEPALGIGEPAFARLARD--VDAVVHNGAL--VNY-VRTYDALRP 854 E + + DLA+ L + V + V Y + A Sbjct: 47 ELLAQPGFQFHKIDLAD------REGMTDLFASGHFERVFISPHRLAVRYSLENPHAYAD 100 Query: 855 TNVEGTRELLRLAMTDHAKTFHLV--SSTFIYGWSTQPVVGEWDANEKMAGLDFGYSQTK 912 +N+ G +L H K HL+ SS+ +YG + + D+ + L Y+ TK Sbjct: 101 SNLTGFLNILEGC--RHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSL---YAATK 155 Query: 913 WVAEQLALA 921 E +A Sbjct: 156 KANELMAHT 164
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 55.4 bits (133), Expect = 4e-11 Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 26/204 (12%) Query: 14 GRTVIVTGANAGLGEVTARELARVGGHVILAVRNTDKGRAAADRMAGVATGRVEVRELDL 73 G+ +TGA G+GE AR LA G H+ N +K + A E D+ Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEAR-HAEAFPADV 66 Query: 74 QDLASVR----RFADGIDTVDVLVNNAGI--MATKHAVTVDGFEGQIGTNHLGHFALTNL 127 +D A++ R + +D+LVN AG+ H+++ + +E N G F + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 128 LLPKLTDR----VVTVSSLMHHFGYISLKDLNFRSRPYSAWLAYSQSKLANLLFTSELQR 183 + + DR +VTV S N P ++ AY+ SK A ++FT L Sbjct: 127 VSKYMMDRRSGSIVTVGS-------------NPAGVPRTSMAAYASSKAAAVMFTKCLG- 172 Query: 184 RLDAVPSSLRALAAHPGWSHTNLQ 207 L+ ++R PG + T++Q Sbjct: 173 -LELAEYNIRCNIVSPGSTETDMQ 195
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 30.9 bits (70), Expect = 0.009 Identities = 24/112 (21%), Positives = 45/112 (40%), Gaps = 21/112 (18%) Query: 161 QTITSIAEKVDPVKLNLTLSAAAQSLSGLGEKFGQSVVNANALLDDVNPRMPQA-----R 215 QTI I +DP K A+ LS L + +V AL+D +P + + Sbjct: 138 QTIALILSYLDPQK-------ASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLE 190 Query: 216 KDIQGLAALGDTYADASPDLFDFLNN-------AVITSRTINAQQKDLDQAL 260 K + L++ T A ++ + +N +I S + + +L + + Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIES--LEEEDPELAEEI 240
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 33.6 bits (76), Expect = 0.004 Identities = 26/66 (39%), Positives = 30/66 (45%), Gaps = 10/66 (15%) Query: 895 PGAGAAATNIQPTEGGAPAASPPANAPAPAVTPGSAP-PVAAP-------PVPDGSVTLS 946 PG+ A A N QP +PA +P AN PAP PG+ P P P P DG Sbjct: 317 PGS-AEAPNAQPLPEVSPAENP-ANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTR 374 Query: 947 PAKAAV 952 P AV Sbjct: 375 PDSPAV 380
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 72.4 bits (177), Expect = 4e-17 Identities = 50/190 (26%), Positives = 86/190 (45%), Gaps = 8/190 (4%) Query: 3 LNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPKLPGTVYTAAKELEEAGGQ 62 + GK FI+GA++GIG A+A+ A GA+IA + E K+ ++ A+ E Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE----- 60 Query: 63 ALPIVGDVRDPESVEAAVAKTIEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQVR 122 A P DVRD +++ A+ + G IDI VN A + G I + + ++ + Sbjct: 61 AFPA--DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNST 118 Query: 123 GTYAVSQACIPHLKGRENPHILTLSPPVLLGKEWLEPTAYMMAKFGMTLCALGIAEEMRE 182 G + S++ ++ R + I+T+ G AY +K + + E+ E Sbjct: 119 GVFNASRSVSKYMMDRRSGSIVTVGSNP-AGVPRTSMAAYASSKAAAVMFTKCLGLELAE 177 Query: 183 AGIASNTLWP 192 I N + P Sbjct: 178 YNIRCNIVSP 187
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 83.9 bits (207), Expect = 2e-21 Identities = 66/253 (26%), Positives = 93/253 (36%), Gaps = 27/253 (10%) Query: 13 VLVTGGTSGIGNAIATAFADSGAAVTVTGTRAAATGYPDIDLGAFSYRQ----CHIQDPE 68 +TG GIG A+A A GA + L A + ++D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 69 SVDALANSLSD----LDILVNNAGGPYPAG-DEYDPDGYVASVTQNMFGPMRLTMRCHDL 123 ++D + + +DILVN AG P + + A+ + N G + + Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS---RSV 127 Query: 124 LKSSRAAGGASVVNVVSMSAFRSAVFVPGYASSKMGLVALTMNLSRRWAGDGIRVNAIAP 183 K S+V V S A + YASSK V T L A IR N ++P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 184 GLIDTRMTHP-----------AMGIPEVMDVEIGFHTPLGRPGTPADCAGAALFLCTEAA 232 G +T M G E I PL + P+D A A LFL + A Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGI----PLKKLAKPSDIADAVLFLVSGQA 243 Query: 233 SYITGSTIAVDGG 245 +IT + VDGG Sbjct: 244 GHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (254), Expect = 4e-28 Identities = 71/266 (26%), Positives = 116/266 (43%), Gaps = 18/266 (6%) Query: 12 MGLRGLADKVAVVVGGATGIGAATAARLAGEGCRVVIGDVAVDAARQTADRIAAAGGTAT 71 M +G+ K+A + G A GIG A A LA +G + D + + + A A Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 72 QVAFDLADPASVATLIDCAATTYGGVDLLFNVGADMSTIRADTDVVDIDFDVWDRVMTVS 131 D+ D A++ + G +D+L NV + + + W+ +V+ Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIH----SLSDEEWEATFSVN 116 Query: 132 LRGYVAAMKYAIPRMLDRGGGAIVNMSSAAAFQGEPARPAYATAKAGIGALTRHVASRWG 191 G A + M+DR G+IV + S A + AYA++KA T+ + Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 192 KDNIRCNAVAPGFTATETIRSVPQWPELEAAALKRIRG-----------PRVGDPADVAT 240 + NIRCN V+PG T T+ S+ W + E A + I+G ++ P+D+A Sbjct: 177 EYNIRCNIVSPGSTETDMQWSL--WAD-ENGAEQVIKGSLETFKTGIPLKKLAKPSDIAD 233 Query: 241 LVAFLLSAEGDWINGQVINIDGGTVL 266 V FL+S + I + +DGG L Sbjct: 234 AVLFLVSGQAGHITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.4 bits (107), Expect = 3e-08 Identities = 18/143 (12%), Positives = 52/143 (36%), Gaps = 4/143 (2%) Query: 6 RSRRRDGDERRRQLCDAAIRVLAEHGSRGLTHGQVDRYAGVPEGTTSYYYRTRAALLQGV 65 R +++ E R+ + D A+R+ ++ G + G++ + AGV G ++++ ++ L Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS-- 60 Query: 66 GKRVAEIDVANLQSVIDEPLDPLSPFAHLARLTMMQASGPGLMLNRARHELLLGAARDPG 125 + E+ +N+ + E ++ + R L+ Sbjct: 61 --EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCE 118 Query: 126 LAETSQIFAGRINSMARDAIAHL 148 + ++ ++ + Sbjct: 119 FVGEMAVVQQAQRNLCLESYDRI 141
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 95.9 bits (238), Expect = 8e-26 Identities = 67/248 (27%), Positives = 106/248 (42%), Gaps = 11/248 (4%) Query: 5 QVAIVTGASSGIGLGCATRLAGTGMAVLGTGRDPKRLAELETAIGDPDRVA-TVAVDLTD 63 ++A +TGA+ GIG A LA G + +P++L ++ +++ R A D+ D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 64 DDAPRRIVDRALQRWGHIDFLINNAGVGSPKPLHETDDDTLDYFLNLMLRAPFRLAREVL 123 A I R + G ID L+N AGV P +H D+ + ++ F +R V Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 124 PHLPP--GSAIINVTSTFAVVGGLRGGAYSAAKGGLTALTTHIACQYGASGIRCNAVAPG 181 ++ +I+ V S A V AY+++K T + + IRCN V+PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 182 VTVTPM-----VEKRLQDPRFRKINTEM---TPHQRLGSVDDIAATVAFLCSPGGSFING 233 T T M ++ + + P ++L DIA V FL S I Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 234 QTIVVDGG 241 + VDGG Sbjct: 249 HNLCVDGG 256
>ENTEROTOXINA#Heat-labile enterotoxin A chain signature. Length = 258 Score = 29.2 bits (65), Expect = 0.039 Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 6/60 (10%) Query: 334 HTVGMLFSPGYPGFLRGVAASGPDEFVVTTSGGQISRYRPEASESEVLADG---FDQLYG 390 H G GY + V A+ P+ F V + Y P E EV A G + Q+YG Sbjct: 88 HLAGQSILSGYSTYYIYVIATAPNMFNVN---DVLGVYSPHPYEQEVSALGGIPYSQIYG 144
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 118 bits (297), Expect = 4e-34 Identities = 78/259 (30%), Positives = 122/259 (47%), Gaps = 15/259 (5%) Query: 8 LEGRVVVVSGAGGGGIGTTVTAMAARAGATVIAVSRSKENLDEHIAPLAARGLAVLPVAA 67 +EG++ ++GA G IG V A GA + AV + E L++ ++ L A A Sbjct: 6 IEGKIAFITGAAQG-IGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 68 DASTDEGIAAVIDQARRADGRLYGLVNVAGGAEPSTWMPSTRVSRTDWRKIFADNLETAF 127 D I + + R G + LVNVAG P +S +W F+ N F Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPG---LIHSLSDEEWEATFSVNSTGVF 121 Query: 128 FMSQAVAAELLARRLPGSIVSISSISGMNTAPFHIAYGTAKSAIAAMTRTMALELAQSAI 187 S++V+ ++ RR GSIV++ S AY ++K+A T+ + LELA+ I Sbjct: 122 NASRSVSKYMMDRR-SGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 188 RVNAVAPGVTETAASRTYVADDPDRDRR----------AIAMGRRGRPEEQAGAILFLLS 237 R N V+PG TET + AD+ ++ I + + +P + A A+LFL+S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 238 ELSSYVTGQTLLVDGGLDL 256 + ++T L VDGG L Sbjct: 241 GQAGHITMHNLCVDGGATL 259
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 80.9 bits (199), Expect = 8e-20 Identities = 54/192 (28%), Positives = 83/192 (43%), Gaps = 13/192 (6%) Query: 14 RVAVVTGAGRGLGRAYAHLLAARGAKVVVNDVGGALDGAGVDTGPAAQ--VVDEITAAGG 71 ++A +TGA +G+G A A LA++GA + A VD P VV + A Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHI-----------AAVDYNPEKLEKVVSSLKAEAR 57 Query: 72 DAVACTESVATPEGGRAIIETALARYGRLDVLVHNAGNVRRASLKQMSYEDFDAVLDVHL 131 A A V I G +D+LV+ AG +R + +S E+++A V+ Sbjct: 58 HAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNS 117 Query: 132 RGAFHVLRPAFPVMCRAGYGRIVLTSSIGGLYGNQGVANYAAAKAGVIGLSNVAALEGAA 191 G F+ R M G IV S +A YA++KA + + LE A Sbjct: 118 TGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE 177 Query: 192 EGVRCNVIVPAA 203 +RCN++ P + Sbjct: 178 YNIRCNIVSPGS 189
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 28.9 bits (65), Expect = 0.021 Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 4/60 (6%) Query: 17 MALVAPVGRGGASVPLPQPVPGIASILPANGAVVGVAHPIVVTFTAPAADRAAVERSIHV 76 AP+G AS+P PQPV P GA VTF + A+ A + + V Sbjct: 454 TIAAAPMGDPNASIPTPQPV----HYRPMFGAYGRSRTNSSVTFVSQASLDAGLAGRLGV 509
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 43.5 bits (102), Expect = 4e-07 Identities = 39/182 (21%), Positives = 67/182 (36%), Gaps = 31/182 (17%) Query: 44 RPCADSAALVLIDVQR---DFYADDAPMRVEGTSAALGAMAELARPFRRRELPIVHVVRL 100 P + A L++ D+Q D + A E + +L + +P+V Sbjct: 25 VPDPNRAVLLIHDMQNYFVDAFTAGASPVTE----LSANIRKLKNQCVQLGIPVV----- 75 Query: 101 YRADGSNADPVRRRFIEDGARVAVPGSPGSQ-IAPELLPKAVELDHQLLLSGGFQQIGPA 159 Y A + +P R + D + P + I EL P+ Sbjct: 76 YTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPE------------------DD 117 Query: 160 EHVMYKPRWGAFYGTKLVQHLRESGTDTLVFAGCNFPNCPRTSIYEASERDFRIVLVADA 219 + V+ K R+ AF T L++ +R+ G D L+ G + EA D + V DA Sbjct: 118 DLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDA 177 Query: 220 IS 221 ++ Sbjct: 178 VA 179
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 352 bits (904), Expect = e-114 Identities = 146/684 (21%), Positives = 268/684 (39%), Gaps = 74/684 (10%) Query: 23 IRNVVLVGPSGGGKTTLVEALLVAAGVLNRPGSVADGSTVCDYDEAEIRQQRSVGVAVAS 82 I N+ ++ GKTTL E+LL +G + GSV G+T D E ++ ++ + S Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 83 LSHDGVKVNLVDTPGYADFVGELRAGLRAADCALFVIAANEGVDEPTKLLWQECNQVGMP 142 + KVN++DTPG+ DF+ E+ L D A+ +I+A +GV T++L+ ++G+P Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 143 RAVVITKLDHARANYAEALAAAQNAFGDKVLPLYLPTGLPACTGLIGLLSQQRYAYADGK 202 I K+D + + + +++ Q+ Y + Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIK-----------------QKVELYPN-- 163 Query: 203 RAVRPPDPADAAQIEAARGTLIEGIIEESEDESLMERYLGGESIDETVLIADLERAVARG 262 + + ++ Q + T+IEG ++ L+E+Y+ G+S++ L + Sbjct: 164 --MCVTNFTESEQWD----TVIEG------NDDLLEKYMSGKSLEALELEQEESIRFHNC 211 Query: 263 SFFPVIPVCSSTGVGTLELLEVATRGFPSPMEHPLPEVFTQVGAPRAGLACDPDGPLLAE 322 S FPV + +G L+EV T F S L + Sbjct: 212 SLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH-------------------RGQSELCGK 252 Query: 323 VVKTTSDPYVGRVSLVRVFSGTIRPDATVHVSGHFASFFGTGNGNGHAHPDHDEDERIGV 382 V K R++ +R++SG + +V +S E +I Sbjct: 253 VFKIEYSEKRQRLAYIRLYSGVLHLRDSVRIS-------------------EKEKIKITE 293 Query: 383 LSFPLGKQQRPASAVVAGDICAIGKLSRAETGDTLSDKSEPLVLKPWTMPEPLLPVAIAA 442 + + + +G+I I + + L D + P PLL + Sbjct: 294 MYTSINGELCKIDKAYSGEI-VILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEP 352 Query: 443 HAKTDEDKLSVGLGRLAAEDPTLRIEQNQETHQIVLWCMGESHAGVVLDALANRYGVTVD 502 + L L ++ DP LR + TH+I+L +G+ V L +Y V ++ Sbjct: 353 SKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIE 412 Query: 503 TVELRLPLRETFAGKAKGHGRHVKQSGGHGQYAVCDIEVEPLPEGSGFEFVDKVVGGAVP 562 E + E KA+ + + +A + V PLP GSG ++ V G + Sbjct: 413 IKEPTVIYMERPLKKAE--YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLN 470 Query: 563 RQFIPSVEKGVRAQMEKGVHAGYPVVDIRVTLLDGKAHSVDSSDFAFQMAGALALREAAA 622 + F +V +G+R E+G++ G+ V D ++ G +S S+ F+M + L + Sbjct: 471 QSFQNAVMEGIRYGCEQGLY-GWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLK 529 Query: 623 ATKVVLLEPIDEISVLVPDDFVGAVMGDLSGRRGRVLGTDTAGHERTVVKAEVPQVELTR 682 LLEP + P +++ D ++ T +E ++ E+P + Sbjct: 530 KAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNE-VILSGEIPARCIQE 588 Query: 683 YAIDLRSLAHGAASFTRSFARYEP 706 Y DL +G + Y Sbjct: 589 YRSDLTFFTNGRSVCLTELKGYHV 612
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 46.9 bits (111), Expect = 5e-08 Identities = 30/167 (17%), Positives = 56/167 (33%), Gaps = 28/167 (16%) Query: 86 GTGIVIDPNGVVLTNNHVISGATE----ISAF------DVGNGQTYAV-DVVGYDRTQDI 134 +G+V+ + +LTN HV+ + AF D + + Y D+ Sbjct: 104 ASGVVVGKD-TLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDL 162 Query: 135 AVLQLRGAAGLPTATIGGEATVGEPIVALG---NVGGQGGTPNAVAGKVVALNQSV--SA 189 A+++ + +GE + N Q V G + + Sbjct: 163 AIVKF--------SPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWES 214 Query: 190 TDTLTGAQENLGGLIQADAPIKPGDSGGPMVNSAGQVIGVDTAATDS 236 +T + +Q D G+SG P+ N +VIG+ + Sbjct: 215 KGKITYLKGEA---MQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPN 258
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 123 bits (309), Expect = 2e-38 Identities = 37/145 (25%), Positives = 61/145 (42%), Gaps = 2/145 (1%) Query: 13 QAARLTELLQKQLSTYNDLHLTLKHIHWNVVGPNFIGVHEMIDPQVEAVRGFADDVAERI 72 + L QLS + L+ L HW V GP+F +HE + + D +AER+ Sbjct: 9 NQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERL 68 Query: 73 AALGASPQGTPGAIIKDRSWDDYSVGRDTVQAHLAALDLVYNGVIEDIRQYIDETDE-LD 131 A+G P T + S D + A ++ Y + + + I +E D Sbjct: 69 LAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVND-YKQISSESKFVIGLAEENQD 127 Query: 132 QVTQDLLIGQAAQLEKFQWFVRAHL 156 T DL +G ++EK W + ++L Sbjct: 128 NATADLFVGLIEEVEKQVWMLSSYL 152
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 90.5 bits (224), Expect = 1e-24 Identities = 31/172 (18%), Positives = 65/172 (37%), Gaps = 4/172 (2%) Query: 13 RPPAAKADETRQRIIQAARLVFSERGYDGATFQAIAARADLTRPAINHYFASKRALYQEV 72 R +A ETRQ I+ A +FS++G + IA A +TR AI +F K L+ E+ Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 73 MDETNEFVIG-VGIKEADRETTLVGRLTAFISAAVKANAENPAGSAFIFGGVLESQRHPE 131 + + + +A + L + +++ + + + E Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 132 W---NTAENDSVRIAREFLIRVVNDAIEHGEVAADIDASALVETLLVVMCGV 180 A+ + + + + + + IE + AD+ + + G+ Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.2 bits (65), Expect = 0.034 Identities = 19/102 (18%), Positives = 31/102 (30%), Gaps = 2/102 (1%) Query: 364 DAPAALDAAVPGSQPPPAPAEPAVLDVVNATTHDGLAAALEEALAGRGFTRGSATTAPTQ 423 + P + +P P P V V + + T + T+ T Sbjct: 85 EPPKEAPVVIEKPKPKPKPKPKPVKKVEQP--KRDVKPVESRPASPFENTAPARPTSSTA 142 Query: 424 AEDSSIEYGPGAEAAARLLADQLHLPATAQSAVAPGTVRLTV 465 +S A L +Q PA AQ+ G V++ Sbjct: 143 TAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 184
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 83.2 bits (205), Expect = 8e-21 Identities = 52/192 (27%), Positives = 84/192 (43%), Gaps = 9/192 (4%) Query: 3 GVQDRVIVVTGAGGGLGREYALTLAREGASVVVNDLGGARDGTGAGHNMADQVVKEIKDA 62 G++ ++ +TGA G+G A TLA +GA + D + ++VV +K Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEK---------LEKVVSSLKAE 55 Query: 63 GGRAVANYDSVAEPAGAENIIKTALDEFGAVHGVVSNAGILRDGTFHKMLFENWDAVLKV 122 A A V + A + I E G + +V+ AG+LR G H + E W+A V Sbjct: 56 ARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSV 115 Query: 123 HLYGGYNVIRAAWPHFREQSYGRVVVATSTSGLFGNFGQTNYGAAKLGLVGLINSLALEG 182 + G +N R+ + ++ G +V S Y ++K V L LE Sbjct: 116 NSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 183 AKYNIHANAIAP 194 A+YNI N ++P Sbjct: 176 AEYNIRCNIVSP 187
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 31.7 bits (72), Expect = 0.005 Identities = 24/112 (21%), Positives = 45/112 (40%), Gaps = 21/112 (18%) Query: 154 QTITSIAEKVDPVKLNLTLSAAAQSLSGLGEKFGQSVVNANALLDDVNPRMPQA-----R 208 QTI I +DP K A+ LS L + +V AL+D +P + + Sbjct: 138 QTIALILSYLDPQK-------ASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLE 190 Query: 209 KDIQGLAALGDTYADASPDLFDFLNN-------AVITSRTINAQQKDLDQAL 253 K + L++ T A ++ + +N +I S + + +L + + Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIES--LEEEDPELAEEI 240
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 28.7 bits (64), Expect = 0.018 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 8/59 (13%) Query: 152 ALDPQKVNTIATALVTVFQGQGG--------TINDILDQTAQLTSQLGERDQAIGEVIK 202 AL+ QK T +A VFQ GG I+ I+D +LT +LG I E+++ Sbjct: 22 ALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLR 80
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 31.5 bits (71), Expect = 0.006 Identities = 25/127 (19%), Positives = 34/127 (26%), Gaps = 9/127 (7%) Query: 392 LPRPDNPLPCAGAVTGPFGGPGFPAPVDVMTSPPNPAGLPPTPGIPIAGRPGDAPPDVPG 451 LP P P ++ P P + PP P P PI P +AP + Sbjct: 43 LPAPAQP------ISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEK 96 Query: 452 ---TPVPLPTQAPPGARTENLAPAGPVPPPSTFAPGAAAGSAGTPRAGQPVAGAVHQPRR 508 P P P + + P S F A A + Sbjct: 97 PKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Query: 509 DRRQRRS 515 R R+ Sbjct: 157 PRALSRN 163
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 31.1 bits (70), Expect = 0.010 Identities = 15/41 (36%), Positives = 17/41 (41%) Query: 492 APVPIPPPPPGPGVAPGPVAPTPAPVSAPAPNAGGPAAPAD 532 APV I P P P P PV P P PA+P + Sbjct: 90 APVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFE 130
>PF07328#T-DNA border endonuclease VirD1 Length = 144 Score = 29.3 bits (65), Expect = 0.015 Identities = 11/62 (17%), Positives = 21/62 (33%) Query: 241 ADTKQLLINAVDSVGRLSQAADQYLSEARGPLHTDLQALQCPLKELGKASPYLIGALKLI 300 A T +LL + ++ ++ +Q A + K LG L L + Sbjct: 65 AKTVELLRDMSRAIAGVATNINQIAKAANRTHDPAYHSFMAERKVLGLELSKLSAVLAPL 124 Query: 301 LT 302 + Sbjct: 125 ME 126
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.1 bits (91), Expect = 2e-05 Identities = 25/163 (15%), Positives = 62/163 (38%), Gaps = 1/163 (0%) Query: 44 ALPAIARNLQVSLVLVGTLLSWYALVAALTTIPLVRWTAHLPRRRVLVASLTCLTASQLI 103 +LP IA + + + + L ++ T + + L +R+L+ + +I Sbjct: 36 SLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVI 95 Query: 104 SALAPNFA-VLAAGRVLCAITHGLLWSVIAPIATRLVPPSHAGRATMSIYVGTSLALVVG 162 + +F +L R + +++ + R +P + G+A I ++ VG Sbjct: 96 GFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVG 155 Query: 163 SPLTAALSLMWGWRLAVVCVTVAAAVVTVAARLMLPEMVLTEH 205 + ++ W ++ + V +L+ E+ + H Sbjct: 156 PAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGH 198
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 39.6 bits (92), Expect = 1e-05 Identities = 20/101 (19%), Positives = 29/101 (28%), Gaps = 12/101 (11%) Query: 37 PALADPDPAPADPGAVAAPPGPPAPPDPLAPPPPPDPLAPPPPAAPPAPW---------- 86 PA +P A P P P P P P P + P P P P Sbjct: 52 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPK 111 Query: 87 --LPPAAQPAAAPAAGQDPTPFTGTPPFGPPTFVPKTGSTV 125 + P A+P P T + + + ++ Sbjct: 112 RDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASG 152 Score = 31.9 bits (72), Expect = 0.003 Identities = 22/92 (23%), Positives = 24/92 (26%), Gaps = 5/92 (5%) Query: 44 PAPADPGAVA--APPGPPAPPDPLAPPPPPDPLAPPPPAAPPAPWLPPAAQPAAAPAAGQ 101 PAPA P +V P P PP P P P P P P P Sbjct: 39 PAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 98 Query: 102 DPTPFTG---TPPFGPPTFVPKTGSTVGVAQP 130 P P P + S P Sbjct: 99 KPKPVKKVQEQPKRDVKPVESRPASPFENTAP 130
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 37.7 bits (87), Expect = 1e-05 Identities = 20/143 (13%), Positives = 55/143 (38%), Gaps = 3/143 (2%) Query: 2 RSPREKMVVSAALLIRERGAHATAISDVLEHSGAPRGSAYHYFPGGRTQLLCEAVDFAGE 61 + R+ ++ A L ++G +T++ ++ + +G RG+ Y +F ++ L E + + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHF-KDKSDLFSEIWELSES 68 Query: 62 YVAAVIAG--AESGSRLLDTLIDTYREQLRDSDFRAGCPVVAVAVEAGEQSDAERPVIER 119 + + A+ L L + L + ++ + + E V+++ Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 120 AAAAFDRWTDLIAQRFVADGIRR 142 A + ++ + I Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEA 151
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 68.3 bits (167), Expect = 1e-13 Identities = 42/227 (18%), Positives = 88/227 (38%), Gaps = 22/227 (9%) Query: 186 VILIVLLAVFGSLAAAAIPLALGICTVVVTMGLVYLLSAYTTMSVFVTSTVSMFGIALA- 244 ++ +V+ ++ A IP V V + + + A S+ +T++MFG+ LA Sbjct: 350 LVFLVMYLFLQNMRATLIPTI----AVPVVLLGTFAILAAFGYSI---NTLTMFGMVLAI 402 Query: 245 ---VDYSLFILMRFREELRSGR-QPREAVDAAMATSGLAVVLSGMTVIASLTGIYVINTP 300 VD ++ ++ + + P+EA + +M+ A+V M + A + Sbjct: 403 GLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGS 462 Query: 301 A---LKSMATGAILAVAVAMLTSTTLTPAALATFGRAAAK-----RSALLHWSRRPESTQ 352 + + + A+A+++L + LTPA AT + + + W Sbjct: 463 TGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHS 522 Query: 353 SKFWNRWIGWVMRRPWMSALAASLVLLVMAAPAASMVLGNSLLRQFD 399 + +G ++ L L+V + L +S L + D Sbjct: 523 VNHYTNSVGKILGSTGRYLLIY--ALIVAGMVVLFLRLPSSFLPEED 567
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 29.1 bits (64), Expect = 0.010 Identities = 25/58 (43%), Positives = 30/58 (51%), Gaps = 8/58 (13%) Query: 2 TSASAGRRRRIFAGLIAAALPGAAVAVLAGPPATGANDPCAASEVARTIGSVSKSMGD 59 +ASA I G A A GAAVAV AG ATG N + IG +SK++GD Sbjct: 63 LNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVN--------SVAIGPLSKALGD 112
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 57.9 bits (140), Expect = 2e-10 Identities = 35/233 (15%), Positives = 83/233 (35%), Gaps = 34/233 (14%) Query: 193 AVPMVAVVLFLVFGGAVAAGLPAIVGGLSIAGSLGILRLVAVFGPVHYFAQPVVSLIGL- 251 A+ +V +V++L A +P I + + G+ IL FG ++ +++ G+ Sbjct: 347 AIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAA---FG----YSINTLTMFGMV 399 Query: 252 ---GIAIDYGLFVVSRF-REEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIIASSASLLVL 307 G+ +D + VV R + + + A +++ + A+++ A + Sbjct: 400 LAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFF 459 Query: 308 P--QG-FVHSLTYAIFAAVGLAALLSITFLPACLGILGRHVDALGVRTAFRVPFLRNWKY 364 G + I +A+ L+ L+++ PA L L +A + Sbjct: 460 GGSTGAIYRQFSITIVSAMALSVLVALILTPALCATL------LKPVSAEHHENKGGF-- 511 Query: 365 SRAYLNWLADRLQKTKTREEVEAGFWGKLVNWVMRKPLAFAIPIAVGMILLVI 417 W + + V ++ + + A+ + +V+ Sbjct: 512 ----FGWFNTTFDHSVNH-------YTNSVGKILGSTGRYLLIYALIVAGMVV 553 Score = 50.6 bits (121), Expect = 3e-08 Identities = 39/209 (18%), Positives = 78/209 (37%), Gaps = 23/209 (11%) Query: 534 AKKIAELRAVNPPKGLNLYVGGTPALEQDSIHSLFDKAPLMLVLLLGATLLLMFLAFGSV 593 A + E A P G+ G E+ S ++AP ++ + L + + S Sbjct: 839 AMALMENLASKLPAGIGYDWTGMSYQERLS----GNQAPALVAISFVVVFLCLAALYESW 894 Query: 594 VLPIKAVLMSALTLGSTMGILTWIFVDGHLSGVLNFTPTPLMVVVIALVVAVGFGLATDY 653 +P+ +M + LG +L + MV ++ + GL+ Sbjct: 895 SIPV--SVMLVVPLGIVGVLLAATLFNQKND-------VYFMVGLLTTI-----GLSAKN 940 Query: 654 EVFLVSRMVEARER-GMSTAEAIRIGTATTGR--LITAAAMVLAVVASSFVFSD-LVLMK 709 + +V + E+ G EA + R L+T+ A +L V+ + Sbjct: 941 AILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQN 1000 Query: 710 YLAFGLMAALLLDATVVRMFLVPSVMKLL 738 + G+M ++ AT++ +F VP ++ Sbjct: 1001 AVGIGVMGGMVS-ATLLAIFFVPVFFVVI 1028
>PF06872#EspG protein Length = 398 Score = 29.7 bits (66), Expect = 0.018 Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 2/56 (3%) Query: 185 GVDVPAAARERLLDTLDLFGT--ALAIAAIRRGAGPAQLRTLLRRISGVDAVLAEI 238 GVD+PA A++ L +TL L T + + IR G +++ S + A + Sbjct: 219 GVDIPADAQKLLRNTLGLKDTNSSPDLNVIRNGIPRHYAEQIVKESSSTNEQKAAV 274
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 29.8 bits (67), Expect = 0.017 Identities = 23/149 (15%), Positives = 50/149 (33%), Gaps = 13/149 (8%) Query: 9 VLIGLVMYQRAMASADTKYPEFMQWLARLNSAAVEFVNGIGVVKAFGTPGVASRRFQE-- 66 L G+ + S +P V F + + K R + Sbjct: 51 TLNGVALL----LSMFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKY 106 Query: 67 VSRAFAHFFLD------WAKSTSVAAVIAETLLSPPSILVVVAGAGGALTANGKLPLDSF 120 R FF + + + T + + P ++ A A + + K+ + Sbjct: 107 SDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLY 166 Query: 121 IAFLVFGTVITAGLMTV-MMSIHPLVTAL 148 + F+V V+++ L+ + MM + P+ + Sbjct: 167 LPFVVVDLVVSSVLLALGMMMMSPVTIST 195
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.9 bits (67), Expect = 0.017 Identities = 18/65 (27%), Positives = 24/65 (36%), Gaps = 5/65 (7%) Query: 288 APAPEPVPATVADVPAPTSPPNQALPVAGIPSASTPASAPASAPATSATAPASAPAPAPA 347 P P+P P V V P ++P A A TS+TA A+ P + Sbjct: 98 KPKPKPKPKPVKKVEQPKRDVKPVE-----SRPASPFENTAPARPTSSTATAATSKPVTS 152 Query: 348 SAGSP 352 A P Sbjct: 153 VASGP 157 Score = 29.2 bits (65), Expect = 0.029 Identities = 15/116 (12%), Positives = 26/116 (22%), Gaps = 10/116 (8%) Query: 289 PAPEPVPATVADVPAPTSPPNQALPVAGIPSASTPASAPASAPATSATAPASAPAPAPAS 348 P P P + PP +A V P PAS Sbjct: 70 PEPVVEPEPEPEPIP--EPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPAS 127 Query: 349 AGSPVFGYLVGGGGGGESGPTLTGRSNATAPAGLAAASAAAAKAPTRDQTRSRRRR 404 + + +A+ A ++ + R++ R Sbjct: 128 PFENTAPARPTSSTATAAT--------SKPVTSVASGPRALSRNQPQYPARAQALR 175 Score = 28.8 bits (64), Expect = 0.043 Identities = 11/67 (16%), Positives = 17/67 (25%), Gaps = 2/67 (2%) Query: 288 APAPEPVPATVADVPAPTSPPNQALPVAGIPSASTPASAPASAPATSATAPA--SAPAPA 345 P PEP + P P P + S + P + Sbjct: 81 EPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSS 140 Query: 346 PASAGSP 352 A+A + Sbjct: 141 TATAATS 147
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 124 bits (314), Expect = 4e-33 Identities = 87/408 (21%), Positives = 159/408 (38%), Gaps = 27/408 (6%) Query: 27 FLMTLDITVVNVALPSIQKDLGASLEGLQWVVNAYVLAFAALLLTVGSVSDRLGRKRLFL 86 F L+ V+NV+LP I D WV A++L F+ G +SD+LG KRL L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 87 TGVAVFTVASALCVASRTESP-LIAARALQGIGGALVFGTCLALIADAYTDAEEEQRRKA 145 G+ + S + + LI AR +QG G A + ++A +E R KA Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVA---RYIPKENRGKA 140 Query: 146 VGLAMAAGAAAATLGPLIGGGLVEIGTWQWIFAINVPVGVALAICTALKVREPHAPHAAD 205 GL + A +GP IGG + W + + +P+ + + +K+ + Sbjct: 141 FGLIGSIVAMGEGVGPAIGGMIAH--YIHWSYLLLIPMITIITVPFLMKLLKKEVRI--- 195 Query: 206 NSRVDSVGAVVAIVVLFALNYGLLTGAAKGWGRGDVLAALAIGLAGGVGFVLHQLRRGSE 265 D G ++ V + T + + +++ L+ + FV H R+ ++ Sbjct: 196 KGHFDIKGIILMSVGIVFFMLF-TTSYSISF---LIVSVLSFLI-----FVKHI-RKVTD 245 Query: 266 ATLDLTLFRIPTFLAAIVLGFTVRALSFGVFPFLILWLAGAHGRSAFDIGLILSALALPL 325 +D L + F+ ++ G + G + + H S +IG + + P Sbjct: 246 PFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSV---IIFPG 302 Query: 326 MVCAVLSTSVARAV----GVRATMSIAMVITAAGLFLATLIRGDGSWTTILPALAVLGVG 381 + ++ + + G ++I + + A+ + SW + + VLG G Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-G 361 Query: 382 NGVAMPHLMNLAVDVVPSNKAGMATGAANTAFPLGTATGVAAFGVVLS 429 + + + +AG N L TG+A G +LS Sbjct: 362 LSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 43.5 bits (102), Expect = 8e-06 Identities = 17/66 (25%), Positives = 30/66 (45%) Query: 615 LAQHLAAMLGVEPYELAPDADLTTLGLTSMMTAQIVEWSSSQSRRLDFADLYAEPTLRSW 674 + + +A +L P ++ DL GL S+ +VE + + F +L PT+ W Sbjct: 235 IRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEW 294 Query: 675 QRLFDA 680 Q+L Sbjct: 295 QKLLTT 300
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 96.9 bits (241), Expect = 6e-25 Identities = 52/266 (19%), Positives = 96/266 (36%), Gaps = 30/266 (11%) Query: 90 AIGRTAAPPCPTAPLAVVVSVDQWGDIVSELGGACANVKTVLASSSVDPHDYEPSPADAA 149 A L VV + DI + G ++ + DPH+YEP P D Sbjct: 19 ACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLH-SIVPIGQDPHEYEPLPEDVK 77 Query: 150 DFMNAKLIVVNG----AGYDSWASKLAGSSASGA---PLVSAAAVTTTPDGA-------N 195 A LI NG G ++W +KL ++ + V + Sbjct: 78 KTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKED 137 Query: 196 PHLWYLPSAVTAVADAVTQELSRMEPPAAGYFSQRRAQFTSAT----RLYVNLIAKIKAE 251 PH W A + ++LS +P ++ + ++T + + KI AE Sbjct: 138 PHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAE 197 Query: 252 AAGKSYGATETVFDYQAQAAGLVNKTPAGYRRASANESEPSPGDVDAFLTALAGRHIDLL 311 K +E F Y ++A G+ A + E E +P + + L + L Sbjct: 198 --KKLIVTSEGAFKYFSKAYGV---PSAYIWEINT-EEEGTPEQIKTLVEKLRQTKVPSL 251 Query: 312 IYNTQTEGSIPEE-IRSAAEQSSVPV 336 E S+ + +++ ++ +++P+ Sbjct: 252 F----VESSVDDRPMKTVSQDTNIPI 273
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.038 Identities = 26/179 (14%), Positives = 56/179 (31%), Gaps = 32/179 (17%) Query: 218 ALSYLEEPEGPVAVAAVDGALAKALVLRAHVD---------EDSASEVLQDLYAAHPENE 268 L+ G + A + D +++A ++L + A P+ Sbjct: 18 VLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPDLP 77 Query: 269 QVEQALTDTSFGIVTTTAARIEAR-----TDPWDPETEPSAEDFVDPAAHERKAVLLHEA 323 L ++ T E P+D L E Sbjct: 78 ----VLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTE-----------LIGIIGRALAEP 122 Query: 324 ERQLAEFIGLEEVKNQVSRLKSSVAMELVRKQRGLAVAQRAHHLVFAGPPGTGKTTIAR 382 +R+ ++ ++ ++ + + S AM+ + + + ++ G GTGK +AR Sbjct: 123 KRRPSK--LEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT-GESGTGKELVAR 178
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 34.8 bits (80), Expect = 0.002 Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 11/67 (16%) Query: 24 IEAPPELP-RVIPPSF----LRRAMPYVLVI----LIVGMIVA--LFATGMRLISPQTLF 72 ++ P +P R++ P++ L+ A I LI+ +++A L A GM ++ P T+ Sbjct: 159 LQGPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIA 218 Query: 73 FPFVLLL 79 PF L+L Sbjct: 219 LPFKLML 225
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 28.8 bits (64), Expect = 0.048 Identities = 24/122 (19%), Positives = 34/122 (27%), Gaps = 8/122 (6%) Query: 279 AAPAEIAPVAAPAAITPVLASNKPPTLPAAVALAPSVATPAGAPASTVAAGSGASAAPAP 338 A P + VA PA + P A PP P A V P P Sbjct: 47 AQPISVTMVA-PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP 105 Query: 339 ------AAAAGNFAYLVAFGGDPDTGVGPTLSGRGGAKAPAATIPAAGAAAPARAEARAR 392 + + + P P A A + P A+ RA +R + Sbjct: 106 KPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSK-PVTSVASGPRALSRNQ 164 Query: 393 RR 394 + Sbjct: 165 PQ 166
>PERTACTIN#Pertactin signature. Length = 922 Score = 29.7 bits (66), Expect = 0.029 Identities = 17/51 (33%), Positives = 20/51 (39%) Query: 340 ADQRPEVGTQVVAPDNPPPPSAAPSPPPAAPVPAAPPPQAPVSPAPSPHSG 390 A P P P P PP P P PP + P +PAP P +G Sbjct: 565 AKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAG 615
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 39.6 bits (92), Expect = 1e-05 Identities = 21/61 (34%), Positives = 23/61 (37%), Gaps = 1/61 (1%) Query: 335 PSPNQNVVVAPTRPAPAAPAPAPVQVAPVPVPEAPAPAPAAPPPPPPAVAPIPVPIPLPI 394 P+P Q + V PA P A V P P P P PP A I P P P Sbjct: 39 PAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPI-PEPPKEAPVVIEKPKPKPK 97 Query: 395 P 395 P Sbjct: 98 P 98 Score = 33.0 bits (75), Expect = 0.002 Identities = 13/51 (25%), Positives = 15/51 (29%), Gaps = 1/51 (1%) Query: 339 QNVVVAPTRPAPAAPAPAPVQVAPVPVPEAPAPAPAAPPPPPPAVAPIPVP 389 V P P P P + P EAP P P P P+ Sbjct: 57 PPQAVQPPPEPVVEPEPEPEPIPEPP-KEAPVVIEKPKPKPKPKPKPVKKV 106 Score = 31.5 bits (71), Expect = 0.005 Identities = 16/60 (26%), Positives = 20/60 (33%), Gaps = 1/60 (1%) Query: 348 PAPAAPAPAPVQVAPVPVPEAPAPAPAAPPPPPPAVAPIPVPIPLPIPGLGGPGFGGPPG 407 PAPA P + V P + A P P P P P+P P + P Sbjct: 39 PAPAQPI-SVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK 97
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.041 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 17/87 (19%) Query: 1 MRCTVFGT-GYLGATHAVGMAELGHDVLGVDIDPGKVAKLAGGDIPFYEPGLRKLLNENL 59 M+ V G G++G + + E GH V+G+D L +Y+ L++ E L Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGID-------NLN----DYYDVSLKQARLELL 49 Query: 60 AAGRLRFTT----DYD-MAAGFADVHF 81 A +F D + M FA HF Sbjct: 50 AQPGFQFHKIDLADREGMTDLFASGHF 76
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 38.8 bits (90), Expect = 6e-05 Identities = 24/140 (17%), Positives = 30/140 (21%), Gaps = 32/140 (22%) Query: 778 AATPSPAAPFTPPAAPFTPPFMPPAAAPAPMPPAPADYTQQLFGYLQAWRQYLEQMAGAS 837 A P A PP P P P P PP A Sbjct: 58 ADLEPPQAVQPPPEPVVEP---EPEPEPIPEPPKEA------------------------ 90 Query: 838 SGSAQQPTAPPTAPPTMPPTMPPPPPPPSTPSTGGQAFGAAPPGQPGTSGDPTPGGSTPV 897 P P P A P + PT +T Sbjct: 91 -----PVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAA 145 Query: 898 SATAKGSTLTWPPPLLGLEP 917 ++ S + P L +P Sbjct: 146 TSKPVTSVASGPRALSRNQP 165
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 41.0 bits (96), Expect = 2e-05 Identities = 41/184 (22%), Positives = 67/184 (36%), Gaps = 30/184 (16%) Query: 550 AGRMLEGETAKLLRMEDEL--GKRVVGQKRAVQAVSDAVRRARAGVADPNRPTGSFMFLG 607 GR L + ++ED+ G +VG+ A+Q + + R + + M G Sbjct: 115 IGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR----LMQTDLTL---MITG 167 Query: 608 PTGVGKTELAKALADFLFDDKRAMVRIDMSEYGEKHSVARLVGAPPGYIGYDQGGQLTEA 667 +G GK +A+AL D+ V I+M+ + L G + G T A Sbjct: 168 ESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH--------EKGAFTGA 219 Query: 668 VRRRPYTV-------ILFDEIEKAHPDVFDVLLQVLDEG---RLTDGQGRTVDFRNTILI 717 R + DEI D LL+VL +G + D R ++ Sbjct: 220 QTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IV 276 Query: 718 LTSN 721 +N Sbjct: 277 AATN 280 Score = 30.2 bits (68), Expect = 0.034 Identities = 18/101 (17%), Positives = 39/101 (38%), Gaps = 14/101 (13%) Query: 125 LLTGHGASPQALREAFVKVRGSARVTSPDP-------EATYQALEKYSTDLTARAREG-K 176 +++ A++ A P P +AL + + + Sbjct: 80 VMSAQNTFMTAIKA----SEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQD 135 Query: 177 LDPVIGRDNEIRRVVQVLSRRTKNN-PVLI-GEPGVGKTAI 215 P++GR ++ + +VL+R + + ++I GE G GK + Sbjct: 136 GMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELV 176
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 31.6 bits (71), Expect = 0.003 Identities = 26/73 (35%), Positives = 32/73 (43%), Gaps = 11/73 (15%) Query: 201 PLPEETPQEAPA---APRNSSPSRPLAPAGRAELPPRRAQQDVAGLLGPDVQPGRRAAEP 257 PLPE +P E PA AP + +RP P +L P A D G QPG R P Sbjct: 327 PLPEVSPAENPANNPAPNENPGTRP-NPEPDPDLNP-DANPDTDG------QPGTRPDSP 378 Query: 258 VRRDQPRPEARPD 270 D+P R + Sbjct: 379 AVPDRPNGRHRKE 391
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 70.5 bits (172), Expect = 2e-16 Identities = 50/184 (27%), Positives = 86/184 (46%), Gaps = 4/184 (2%) Query: 5 VALITGPTSGIGAGYARRYASDGYDLVLVARDVDRLTALAGELRDRAGNIEILPADLGDA 64 +A ITG GIG AR AS G + V + ++L + L+ A + E PAD+ D+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 65 ADRQRVAERLA---AGVRVLVNNAGFATSGDFWHTDPALLQSQLDVNVTAVMHLTRAALP 121 A + R+ + +LVN AG G ++ VN T V + +R+ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 122 AMLDAGAGTVINIASIAGLLPGRG-STYSASKAWVISFSEGLSVGLQGTGVSVHAVCPGY 180 M+D +G+++ + S +P + Y++SKA + F++ L + L + + V PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 181 VRTE 184 T+ Sbjct: 190 TETD 193
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 479 bits (1234), Expect = e-172 Identities = 179/397 (45%), Positives = 250/397 (62%), Gaps = 20/397 (5%) Query: 9 RVLVINSGSSSLKFQLVDPEFGVAASTGIVERIGEESS---------------PVPDHDA 53 ++LVIN GSSSLK+QL++ + G + G+ ERIG S + DH Sbjct: 2 KILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKD 61 Query: 54 ALRRAFDMLAGD--GVDLNTAGLVAVGHRVVHGGNTFYRPTVLDDAVIARLHELSELAPL 111 A++ D L GV + + + AVGHRVVHGG F ++ D V+ + + ELAPL Sbjct: 62 AIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121 Query: 112 HNPPALQGIEVARRLLPDIAHVAVFDTGFFHDLPPAAATYAIDRELADRWQIRRYGFHGT 171 HNP ++GI+ +++PD+ VAVFDT F +P A Y I E +++IR+YGFHGT Sbjct: 122 HNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGT 181 Query: 172 SHRYVSEQAAAFLDRPLRGLKQIVLHLGNGCSASAIAGTRPLDTSMGLTPLEGLVMGTRS 231 SH+YVS++AA L++P+ LK I HLGNG S +A+ + +DTSMG TPLEGL MGTRS Sbjct: 182 SHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRS 241 Query: 232 GDIDPSIVSYLCHTAGMGVDDVESMLNHRSGVVGLSGV-RDFRRLREL-IESGDGAAQLA 289 G IDPSI+SYL + ++V ++LN +SGV G+SG+ DFR L + ++GD AQLA Sbjct: 242 GSIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQLA 301 Query: 290 YSVFTHRLRKYIGAYLAVLGHTDVISFTAGIGENDAAVRRDAVSGMEELGIVLDERRNLA 349 +VF +R++K IG+Y A +G DVI FTAGIGEN +R + G+E LG LD+ +N Sbjct: 302 LNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNKV 361 Query: 350 GGKGARQISADDSPITVLVVPTNEELAIARDCVRVLG 386 G+ A IS DS + V+VVPTNEE IA+D +++ Sbjct: 362 RGEEAI-ISTADSKVNVMVVPTNEEYMIAKDTEKIVE 397
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 48.0 bits (114), Expect = 4e-09 Identities = 22/44 (50%), Positives = 29/44 (65%) Query: 24 AKLSREGIIDGALTFLDREGWDALTINALATQLGTKGPSLYNHV 67 A+L+RE +ID AL L+ G D LT LA +LG + P+LY HV Sbjct: 2 ARLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHV 45
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 589 bits (1519), Expect = 0.0 Identities = 161/676 (23%), Positives = 311/676 (46%), Gaps = 71/676 (10%) Query: 12 KVRNIGIMAHIDAGKTTTTERILYYTGISYKIGEVHDGAATMDWMEQEQERGITITSAAT 71 K+ NIG++AH+DAGKTT TE +LY +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 72 TCFWNDNQINIIDTPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYDV 131 + W + ++NIIDTPGH+DF EV RSL VLDGA+ + K+GV+ Q+ ++ K + Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 132 PRICFVNKMDKIGADFYFSVRTMEERLGANVIPIQIPVGSEGDFEGVVDLVEMKAKVWSA 191 P I F+NK+D+ G D + ++E+L A ++ Q Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ------------------------- 156 Query: 192 EAKLGEKYDVVDIPADLQEKAEEYRTKLLEAVAETDEALLDKYLGGEELTIEEIKGAIRK 251 + +L V + ++E++ + V E ++ LL+KY+ G+ L E++ Sbjct: 157 KVELYPNMCVTNFT-----ESEQW-----DTVIEGNDDLLEKYMSGKSLEALELEQEESI 206 Query: 252 LTISSEAYPVLCGSAFKNKGVQPMLDAVIDYLPSPLDVPPAEGHVPGKEEELITRKPSTD 311 + +PV GSA N G+ +++ + + S Sbjct: 207 RFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH--------------------RGQ 246 Query: 312 EPFSALAFKVATHPFFGKLTYVRVYSGKVDSGSQVINSTKGKKERLGKLFQMHSNKENPV 371 FK+ +L Y+R+YSG + V S K K ++ +++ + + + Sbjct: 247 SELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-KITEMYTSINGELCKI 305 Query: 372 ETASAGHIYAVIG----LKDTTTGDTLSDPNHQIVLESMTFPDPVIEVAIEPKTKSDQEK 427 + A +G I + L GDT P E + P P+++ +EP +E Sbjct: 306 DKAYSGEIVILQNEFLKLNS-VLGDTKLLPQR----ERIENPLPLLQTTVEPSKPQQREM 360 Query: 428 LSLSIQKLAEEDPTFKVHLDQETGQTVIGGMGELHLDILVDRMRREFKVEANVGKPQVAY 487 L ++ ++++ DP + ++D T + ++ +G++ +++ ++ ++ VE + +P V Y Sbjct: 361 LLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIY 420 Query: 488 KETIRRKVENVEYTHKKQTGGSGQFAKVIINLEPFTGEDGATYEFENKVTGGRIPREYIP 547 E R ++ EYT + + +A + +++ P G+ ++E+ V+ G + + + Sbjct: 421 ME---RPLKKAEYTIHIEVPPNPFWASIGLSVSP--LPLGSGMQYESSVSLGYLNQSFQN 475 Query: 548 SVDAGAQDAMQYGVLAGYPLVNLKVTLLDGAFHEVDSSEMAFKIAGSQVLKKAAAQAQPV 607 +V G + + G L G+ + + K+ G ++ S+ F++ VL++ +A Sbjct: 476 AVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTE 534 Query: 608 ILEPIMAVEVTTPEDYMGDVIGDLNSRRGQIQAMEERSGARVVKAHVPLSEMFGYVGDLR 667 +LEP ++ ++ P++Y+ D I + ++ ++ +P + Y DL Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLT 594 Query: 668 SKTQGRANYSMVFDSY 683 T GR+ Y Sbjct: 595 FFTNGRSVCLTELKGY 610
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 79.5 bits (196), Expect = 4e-18 Identities = 54/160 (33%), Positives = 80/160 (50%), Gaps = 23/160 (14%) Query: 13 VNIGTIGHVDHGKTTLTAAITKVLHDKYPDLNESRAFDQI----------DNAPEERQRG 62 +NIG + HVD GKTTLT ++ L S A ++ DN ERQRG Sbjct: 4 INIGVLAHVDAGKTTLTESL----------LYNSGAITELGSVDKGTTRTDNTLLERQRG 53 Query: 63 ITINISHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHV 122 ITI +Q + +D PGH D++ + + +DGAIL+++A DG QTR Sbjct: 54 ITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILF 113 Query: 123 LLARQVGVPYILVALNKADMVDDEELLELVEMEVRELLAA 162 R++G+P I +NK D + L V +++E L+A Sbjct: 114 HALRKMGIPTI-FFINKIDQNGID--LSTVYQDIKEKLSA 150
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 118 bits (297), Expect = 3e-34 Identities = 84/273 (30%), Positives = 127/273 (46%), Gaps = 23/273 (8%) Query: 5 AGSLQGRVAFITGAARGQGRSHAVRLAAEGADIIACDICAPVSASVTYAPASPEDLDETA 64 A ++G++AFITGAA+G G + A LA++GA I A D +PE L++ Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVD-------------YNPEKLEKVV 49 Query: 65 RLVEDQGRKALTRVLDVRDDAALRELVADGMEQFGRLDVVVANAGVLSWGRVWELTDEQW 124 ++ + R A DVRD AA+ E+ A + G +D++V AGVL G + L+DE+W Sbjct: 50 SSLKAEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEW 109 Query: 125 DTVIGVNLTGTWRTLRATVPAMIEAGNGGSIVVVSSSAGLKATPGNGHYSASKHGLTALT 184 + VN TG + R+ M GSIV V S+ Y++SK T Sbjct: 110 EATFSVNSTGVFNASRSVSKYM-MDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFT 168 Query: 185 NTLAIELGEYGIRVNSIHPYSVETPM-----IEPEAMMEIFARHPSFVHSFPPMPVQPNG 239 L +EL EY IR N + P S ET M + ++ + +F + Sbjct: 169 KCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIK---GSLETF-KTGIPLKK 224 Query: 240 FMTADEVADVVAWLAGDGSGTLTGTQIPVDKGA 272 ++AD V +L +G +T + VD GA Sbjct: 225 LAKPSDIADAVLFLVSGQAGHITMHNLCVDGGA 257